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Results 251 - 300 of 1843
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Kim Heezoo - - 2012
Background:The activated clotting time (ACT) is widely used for monitoring heparin anticoagulation during cardiac surgery. Celite-based ACT values are prolonged when aprotinin is administered. MDCO-2010, a novel serine protease inhibitor, is currently being evaluated as a possible alternative to aprotinin. Therefore, we evaluated the in vitro effects of this novel ...
Ilizaliturri-Hernández César Arturo - - 2012
The Coatzacoalcos Region in Veracruz, Mexico houses one of the most important industrial complexes in Mexico and Latin America. Lead is an ubiquitous environmental pollutant which represents a great risk to human health and ecosystems. Amphibian populations have been recognized as biomonitors of changes in environmental conditions. The purpose of ...
Kawaguchi Hiroshi - - 2012
The aim of the present study was to test the hypothesis that cortical surface arteries and parenchymal blood flow are independently regulated depending on the perturbation. To this end, a novel image-based analytical method for quantitatively measuring vessel diameters and flow dynamics was developed. The algorithm relies on the spatiotemporal ...
Schroeder Christiane - - 2012
Object The aim of this study was to evaluate and compare CSF flow after endoscopic third ventriculostomy (ETV) and endoscopic aqueductoplasty (EAP) in patients presenting with obstructive hydrocephalus caused by aqueductal stenosis. Methods In patients harboring aqueductal stenosis who underwent EAP (n = 8), ETV (n = 8), and both ...
Qiu Deqiang D Department of Radiology, Stanford University, CA, USA. - - 2012
Functional MRI (fMRI) brain studies performed in the presence of a steady-state or "blood pool" contrast agent yields activation maps that are weighted for cerebral blood volume (CBV). Previous animal experiments suggest significant contrast-to-noise ratio (CNR) improvements, but these studies have not yet been performed in humans due to the ...
Münster P - - 2012
Johne's disease is caused by Mycobacterium avium ssp. paratuberculosis (MAP) and has been recognized as an important bacterial infection in ruminants. Although MAP has been detected in semen and within the reproductive organs of bulls, the bacterial distribution and shedding patterns are currently not well characterized. Our investigation was performed ...
Patil Vishal V Department of Radiology, Center for Biomedical Imaging, New York University School of Medicine, New York 10016-3295, USA. - - 2013
The accuracy of perfusion measurements using dynamic, susceptibility-weighted, contrast-enhanced MRI depends on estimating contrast agent concentration in an artery, i.e., the arterial input function. One of the difficulties associated with obtaining an arterial input function are partial volume effects when both blood and brain parenchyma occupy the same pixel. Previous ...
Gao Bin - - 2012
The intra-aorta pump is a novel continuous flow (CF) left ventricular (LV) device. According to literatures, the pulsatile flow LV device can provide superior LV unloading and circulatory support compared with CF LV assist devices at the same level of ventricular assist device flow. Therefore, a pulsatile control algorithm for ...
Bunck Alexander C - - 2012
OBJECTIVE: To analyse cerebrospinal fluid (CSF) hydrodynamics in patients with Chiari type I malformation (CM) with and without syringomyelia using 4D magnetic resonance (MR) phase contrast (PC) flow imaging. METHODS: 4D-PC CSF flow data were acquired in 20 patients with CM (12 patients with presyrinx/syrinx). Characteristic 4D-CSF flow patterns were ...
Navickis Roberta J - - 2012
The effects of hydroxyethyl starch on bleeding after cardiopulmonary bypass were determined. A meta-analysis was performed of postoperative blood loss in randomized clinical trials of hydroxyethyl starch versus albumin for fluid management in adult cardiopulmonary bypass surgery. Impacts of hydroxyethyl starch molecular weight and molar substitution were assessed. Randomized trials ...
Krieger Steffen Norbert - - 2012
Cerebral blood volume (CBV) changes significantly with brain activation, whether measured using positron emission tomography, functional magnetic resonance imaging (fMRI), or optical microscopy. If cerebral vessels are considered to be impermeable, the contents of the skull incompressible, and the skull itself inextensible, task- and hypercapnia-related changes of CBV could produce ...
Degarege Abraham - - 2012
Studies elucidate conflicting results about the relationships between ABO blood groups and Plasmodium infection outcomes in humans. This study examined association between ABO blood group and Plasmodium falciparum (P. falciparum) malaria related outcomes among 1065 malaria suspected febrile patients who attended Dore Baafano Health Center, southern Ethiopia, between December, 2010 ...
Huang Tzung-Chi - - 2012
BACKGROUND: Digital subtraction angiography (DSA) provides detailed hemodynamic information. However, the imaging interpretation is mainly based on the physician's experience and observation. We aimed to quantitatively study the peritherapeutic blood flow changes of a cerebral arteriovenous malformation (AVM) treated by embolization using optical flow estimation on DSA. METHODS: A 37-year-old ...
Mansoor G Farooq - - 2012
BACKGROUND: The purpose of this study was to assess functionality and resources of facilities providing blood collection and transfusion services in Afghanistan. STUDY DESIGN AND METHODS: This national cross-sectional assessment included facilities collecting or transfusing blood identified through official data sources and private key informants. At each facility, study representatives ...
Hautvast Gilion G Imaging Systems—MR, Philips Healthcare, Best 5684 PC, Netherlands. - - 2012
We have evaluated the use of deconvolution using an exponential approximation basis for the quantification of myocardial blood flow from perfusion cardiovascular magnetic resonance. Our experiments, based on simulated signal intensity curves, phantom acquisitions, and clinical image data, indicate that exponential deconvolution allows for accurate quantification of myocardial blood flow. ...
O'Toole Amanda C AC Fish Ecology and Conservation Physiology Laboratory, Department of Biology, Carleton University, 1125 Colonel By Dr., Ottawa, Ontario, Canada K1S 5B6. - - 2012
Ciguatera in humans is typically caused by the consumption of reef fish that have accumulated Ciguatoxins (CTXs) in their flesh. Over a six month period, we captured 38 wild adult great barracuda (Sphyraena barracuda), a species commonly associated with ciguatera in The Bahamas. We sampled three tissues (i.e., muscle, liver, ...
Kalaska Bartlomiej - - 2012
Heparin is a natural polymer widely used in medicine especially during the treatment of cardiovascular diseases since it is a potent blood anticoagulant. In case of emergency, e.g., massive hemorrhage, the anticoagulant activity of heparin has to be quickly stopped by the administration of a heparin reversing agent. Currently protamine ...
Hahn Andreas - - 2012
Image-derived input functions (IDIFs) represent a promising technique for a simpler and less invasive quantification of PET studies as compared to arterial cannulation. However, a number of limitations complicate the routine use of IDIFs in clinical research protocols and the full substitution of manual arterial samples by venous ones has ...
Janko Marek - - 2012
Changes in elasticity and structures of red blood cells (RBCs) are important indicators of disease, and this makes them interesting for medical studies. In forensics, blood analyses represent a crucial part of crime scene investigations. For these reasons, the recovery and analysis of blood cells from ancient tissues is of ...
Gottesman Rebecca F - - 2012
Anemia has been associated with elevated cerebral blood flow (CBF) in animal models and certain clinical conditions (eg, renal disease), but whether hemoglobin level variations across a relatively normal range are associated with local or diffuse CBF changes is unclear. We investigated whether lower hemoglobin is associated with regional increases ...
Mendez Sarah J - - 2012
As part of a scheduled policy and procedure review, the department of nursing education at a large urban academic medical center conducted a literature review to determine the most up-to-date evidence for central venous access device (CVAD) blood draws. The literature review revealed that the dead space blood draw was ...
Seruya Mitchel - - 2012
Object Controlled hypotension is routinely used during open repair of craniosynostosis to decrease blood loss, although this benefit is unproven. In this study the authors analyzed the longitudinal relationships between intraoperative mean arterial pressure (MAP) and calculated blood loss (CBL) during frontoorbital advancement (FOA) for craniosynostosis. Methods The authors reviewed ...
Doenitz Christoph A - - 2012
The aim of this study was to demonstrate whether it is possible to objectively assess the effects of acupuncture by microcirculation-related parameters in the given clinical scenario, to evaluate the significance of the status of capillary perfusion prior to acupuncture for the treatment of a clinical cold pattern, and to ...
Konokhova Anastasiya I - - 2012
We describe a novel approach to study blood microparticles using the scanning flow cytometer, which measures light scattering patterns (LSPs) of individual particles. Starting from platelet-rich plasma, we separated spherical microparticles from non-spherical plasma constituents, such as platelets and cell debris, based on similarity of their LSP to that of ...
Ben Romdhane Neila - - 2012
Background: Blood transfusion is a high risk activity. Aim: To evaluate transfusion safety in planned cardiac surgery. Methods: This study was conducted in the blood bank of the Rabta Hospital in two phases: a phase to observe transfusion acts followed by corrective actions and a phase to evaluate the impacts ...
Li Fumin - - 2012
Dried blood spots can be a convenient and ethical means of sampling when analyzing compounds in blood. As with any analytical technique, success of the resulting analyses hinge on the precision and accuracy of sample collection, handling and extraction. In this Special Feature, a new method for dried blood spot ...
Wei Hou Han - - 2012
Sepsis is an adverse systemic inflammatory response caused by microbial infection in blood. This paper reports a simple microfluidic approach for intrinsic, non-specific removal of both microbes and inflammatory cellular components (platelets and leukocytes) from whole blood, inspired by the invivo phenomenon of leukocyte margination. As blood flows through a ...
Spinella Philip C - - 2012
BACKGROUND: Blood operations are constrained by many limitations in combat settings. As a result there are many challenges that require innovative solutions. STUDY DESIGN AND METHODS: This is a descriptive overview of blood product usage and transfusion medicine adaptations that have been employed by the US military to support combat ...
Eren B - - 2012
The aim of the article was to present and discuss the phenomenon of delayed fatal spleen rupture case. A 13-year-old boy was referred to hospital because of his poor general condition, convulsions, tachypnea, shallow breathing, severe paleness, abdominal tenderness, decrease in blood pressure, low blood hemoglobin levels, leukocytosis. Abdominal pain ...
Saha Ratan K - - 2012
A theoretical model investigating the dependence of optoacoustic (OA) signal on blood oxygen saturation (SO(2)) is discussed. The derivations for the nonbandlimited and bandlimited OA signals from many red blood cells (RBCs) are presented. The OA field generated by many RBCs was obtained by summing the OA field emitted by ...
Plag Camille - - 2012
Blood coagulation is a series of biochemical reactions resulting in the mechanical transformation of liquid blood into a gel. As a consequence, ultrasound, being mechanical waves, can provide specific details on the dynamics of coagulation. In fact, previous high-frequency ultrasound monitoring studies have shown drastic changes in ultrasound velocity and ...
Friesen Kristina M - - 2012
Reproductive potential was assessed for stable fly cohorts fed cattle, chicken, or horse blood. Flies provided chicken blood oviposited 20% more eggs per day than did those fed cattle or horse blood. However, flies provided cattle or horse blood were fecund 50% longer. When both egg viability and number of ...
Sasaki Nobuhiko - - 2012
Oxygen transport is believed to primarily occur via capillaries and depends on the oxygen tension gradient between the vessels and tissues. As blood flows along branching arterioles, the O2 saturation drops, indicating either consumption or diffusion. The blood flow rate, the O2 concentration gradient, and Krogh's O2 diffusion constant (K) ...
Park Michael Yong - - 2012
The purpose of this article is to examine the effect of different beam-flow angles on the accuracy of Doppler ultrasound velocity measurements in modern ultrasound systems. A flow phantom was used to create a steady flow of water in a 4.3-mm-diameter tube. Using three different modern university-grade ultrasound systems, flow ...
Lakshminarayanan Subitha - - 2012
Physical activity of moderate intensity for 30 minutes a day, on most days substantially reduces the risk of many chronic diseases. To assess the effect of regular physical activity on blood pressure and blood sugar levels in a rural Indian community This community-based study was carried out in Periakattupalayam and ...
Ray Aniruddha - - 2012
The determination of oxygen levels in blood and other tissues in vivo is critical for ensuring proper body functioning, for monitoring the status of many diseases, such as cancer, and for predicting the efficacy of therapy. Here we demonstrate, for the first time, a lifetime-based photoacoustic technique for the measurement ...
Campbell Ian C - - 2012
Patient-specific computational fluid dynamics (CFD) is a powerful tool for researching the role of blood flow in disease processes. Modern clinical imaging technology such as MRI and CT can provide high resolution information about vessel geometry, but in many situations, patient-specific inlet velocity information is not available. In these situations, ...
Petrofsky Jerrold Scott - - 2012
Measurement of resting blood flow to the skin and other organs is an important indicator of health and disease and a way to assess the reaction to various stimuli and pharmaceutical interventions. However, unlike plasma ions such as sodium or potassium, it is difficult to determine what the proper value ...
Bittencourt Ricardo R Maternity Carmela Dutra, Hospital Naval Marcílio Dias, Santa Catarina, Brazil. - - 2012
With the surgical and anesthetic technology advance the indications for intervention are expanding, as well as the need for blood transfusions. Because of its great scientific value, the content to be exposed is subject for endless discussions that provide different guidelines in various clinical and laboratory aspects. The objective of ...
Bijari Payam B PB Biomedical Simulation Laboratory, Department of Mechanical & Industrial Engineering, and Institute of Biomaterials and Biomedical Engineering, University of Toronto, 5 King's College Road, Toronto, ON, Canada M5S - - 2012
Arterial geometry has long been considered as a pragmatic alternative for inferring arterial flow disturbances, and their impact on the natural history and treatment of vascular diseases. Traditionally, definition of geometric variables is based on convenient shape descriptors, with only superficial consideration of their influence on flow and wall shear ...
Tancredi Felipe B - - 2012
PURPOSE: To compare the performance of pulsed and pseudocontinuous arterial spin-labeling (PASL and pCASL) methods in measuring CO(2) -induced cerebrovascular reactivity (CVR). MATERIALS AND METHODS: Subjects were scanned using both ASL sequences during a controlled hypercapnia procedure and visual stimulation. CVR was computed as the percent CO(2) -induced increase in ...
Vercaigne M - - 2012
Aims: Catheter-related thrombosis is a frequent complication of providing hemodialysis via central venous catheters. The primary aim of this study was to compare the efficacy of an alteplase &ldquo;dwell&rdquo; protocol over 30 minutes (with an additional 90 minutes where necessary) to a new 30 minute &ldquo;push&rdquo; protocol in restoring function ...
De Buyst Julie - - 2012
OBJECTIVE: To determine the hemodynamic impact of fluid restriction in preterm newborns with significant patent ductus arteriosus. STUDY DESIGN: Newborns ≥24 and <32 weeks' gestational age with significant patent ductus arteriosus were eligible for this prospective multicenter observational study. We recorded hemodynamic and Doppler echocardiographic variables before and 24 hours ...
Jeffus Susanne - - 2012
This article provides a concise overview of blood banking and transfusion medicine (BBTM) for the therapeutic apheresis medicine practitioner. It addresses the complete pathway from blood donor qualification to blood collection, to processing and storing blood components, to patient testing, to ordering blood components for therapeutic apheresis (TA) procedures, to ...
Frank Steven M - - 2012
BACKGROUND:: Data can be collected for various purposes with anesthesia information management systems. The authors describe methods for using data acquired from an anesthesia information management system to assess intraoperative utilization of blood and blood components. METHODS:: Over an 18-month period, data were collected on 48,086 surgical patients at a ...
Masaki Nami - - 2012
The purpose of this study was to evaluate the differences in heel blood flow during loading and off-loading in bedridden adults older than 65 years. The patients were divided into three groups based on ankle-brachial pressure index (ABI) and transcutaneous oxygen tension (tcPO(2)): (1) patients with an ABI ≥ 0.8 ...
Baart A Mireille - - 2012
BACKGROUND: Each year, approximately 5% of the invited blood donors is eventually deferred from donation because of low hemoglobin (Hb) levels. Estimating the risk of Hb deferral in blood donors can be helpful in the management of the donation program. We developed and validated a prediction model for Hb deferral ...
Yücel Meryem A MA Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA. - - 2012
Multimodal imaging improves the accuracy of the localization and the quantification of brain activation when measuring different manifestations of the hemodynamic response associated with cerebral activity. In this study, we incorporated cerebral blood flow (CBF) changes measured with arterial spin labeling (ASL), Diffuse Optical Tomography (DOT) and blood oxygen level-dependent ...
Jagadeesan B D - - 2012
SUMMARY:We retrospectively identified 9 consecutive children, 3 males and 6 females (age 5.2 ± 6.3 years, range 1 day to 18 years), with known or suspected AVGs who underwent MR imaging, including SWI, at our institution between January 2007 and March 2011. On the SWI sequence, arterialized blood flow was ...
Rutkowska G - - 2012
BACKGROUND AND PURPOSE:Flow simulations in patient-specific models of the subarachnoid space characterize CSF flow in more detail than MR flow imaging. We extended previous simulation studies by including cyclic CSF flow and patient-specific models in multiple patients with Chiari I. We compared simulation results with MR flow measurements.MATERIALS AND METHODS:Volumetric ...
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