Search Results
Results 201 - 250 of 1843
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Kvaskoff David - - 2012
Dried blood spots (DBS) are a convenient collection and archiving method for blood specimens. The interest in screening certain analytes in neonatal DBS continues to increase for a variety of paediatric disorders. 25-Hydroxyvitamin D(3) (25OHD(3)) is one such analyte. We investigated potential factors that may affect the analysis of 25OHD(3) ...
Elbers Paul W G - - 2012
OBJECTIVE: This study tested the hypothesis that there is a discrepancy between global hemodynamic parameters and microvascular flow in patients before and after successful elective electrical cardioversion (ECV) for atrial fibrillation (AF). DESIGN: Prospective observational study. SETTING: Preanesthesia holding area in a teaching hospital. PARTICIPANTS: Adult patients who underwent successful ...
France Christopher R - - 2012
BACKGROUND: Written and video approaches to donor education have been shown to enhance donation attitudes and intentions to give blood, particularly when the information provides specific coping suggestions for donation-related concerns. This study extends this work by comparing Web-based approaches to donor preparation among donors and nondonors. STUDY DESIGN AND ...
Denier Niklaus - - 2012
We conducted a systematic review on resting state cerebral blood flow activities found in first-episode psychosis (FEP) and during acute effects of cannabinoids and opioids, mental states that can be profoundly different from normal functioning. A main goal was to identify connections of cerebral blood flow measure and regional brain ...
Ninivaggi Marisa - - 2012
BACKGROUND:The calibrated automated thrombogram (CAT) assay in plasma is a versatile tool to investigate patients with hypo- or hypercoagulable phenotypes. The objective was to make this method applicable for whole blood measurements.METHODS:Thin-layer technology and the use of a rhodamine 110-based thrombin substrate appear to be essential for a reliable thrombin ...
Kim Won - - 2012
Background: Elevated blood viscosity has been shown to be independently correlated with cardiovascular risk factors and associated with increased risk of major cardiovascular events, including death and acute myocardial infarction. The aim of the present study was to investigate changes in whole blood viscosity (WBV) at shear rates of 1, ...
de Oliveira Cristiane Alves - - 2012
Objectives- The aim of this study was to investigate the interobserver reliability for measuring ophthalmic artery Doppler indices. Methods- Healthy women (n = 30) were evaluated. The resistive index, pulsatility index, and peak ratio were determined by two independent observers who were blind to each other. A paired t test ...
Pottgiesser Torben - - 2012
Biomarker monitoring can be considered a new era in the effort against doping. Opposed to the old concept in doping control of direct detection of a prohibited substance in a biological sample such as urine or blood, the new paradigm allows a personalized longitudinal monitoring of biomarkers that indicate non-physiological ...
Okafor Chika C - - 2012
Objective-To determine whether an interferon (IFN)-γ response sufficient to categorize cattle as positive for tuberculosis can be detected in blood collected at commencement of exsanguination at slaughter. Animals-15 Holstein cows. Procedures-12 cows were experimentally sensitized by SC injection with inactivated Mycobacterium bovis in mineral oil, which induced an immune response ...
Al-Waleedi A A - - 2012
This study determined the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV ) and associated risk factors among blood donors in Aden city, Yemen. A systematic sample of 469 male blood donors was selected from those attending the national blood bank service in Aden between June and ...
Ates Sezen Canim - - 2012
Aims: According to the WHO, only 5-20% of the total cases of leishmaniasis are symptomatic leishmaniasis; the other cases are identified as asymptomatic leishmaniasis. In recent studies, it has been demonstrated that donor blood plays an important role in the epidemiology of asymptomatic leishmaniasis. However, the number of the studies ...
Brattwall Metha - - 2012
PURPOSE: The aim of this brief review is to provide an update on the theory regarding minimal fresh gas flow techniques for inhaled general anesthesia. The article also includes an update and discussion of the practical aspects associated with minimal-flow anesthesia, including the advantages, potential limitations, and safety considerations of ...
Ionita C - - 2012
Purpose: Flow diverters (FD) are new stent like devices used for selected intracranial aneurysms treatment. The devices are in their initial clinical use and the relation between device parameters, physiological implications and treatment outcome needs to be further investigated. Flow resistance is a parameter which could be used to characterize ...
Throckmorton Amy L - - 2012
Failing single ventricle physiology represents an ongoing challenge in mechanical assist device development, requiring pressure augmentation in the cavopulmonary circuit, reduction of systemic venous pressure, and increased cardiac output to achieve hemodynamic stabilization. To meet these requirements, we are developing a percutaneously-placed, axial flow blood pump to support ailing single ...
Noticewala Manish S - - 2012
Total knee arthroplasty (TKA) can lead to substantial blood loss. To avoid the high costs of autologous blood predonation programs and efficiently allocate limited blood resources, we sought to identify preoperative and intraoperative factors associated with allogeneic blood transfusion (AllTx) after primary TKA and, subsequently, develop a model to predict ...
Oronsky Bryan T - - 2012
This review attempts to move beyond the traditional borders of antiangiogenesis and toward the dynamic, evolving strategies of vascular modulation. This repositioning entails a two-fold paradigm shift: conceptually, to a view of antiangiogenesis as only one part of a larger story, and therapeutically, to approaches which attempt to modulate tumor ...
Dewhirst Elisabeth - - 2012
Preoperative phlebotomy can minimize the need for allogenic blood products. Frequently, removed blood is replaced with intravenous fluids to maintain euvolemia (acute normovolemic hemodilution [ANH]). During cardiopulmonary bypass (CPB), ANH may present problems when the circuit prime causes further hemodilution and unacceptably low hemoglobin. This investigation aimed to demonstrate that ...
Curtis Donald A - - 2012
Purpose: Although changes in blood perfusion have been described as being associated with temporomandibular disorder (TMD) myofascial pain, very little is known about blood flow levels in the deep and superficial masseter muscle. This study investigated blood flow in deep and superficial sites of six healthy female particpants at baseline ...
Vucinic Aleksandra Anic - - 2012
Effective wastewater purification in subsurface flow constructed wetlands must include adequate pretreatment and ensure a sufficient amount of dissolved oxygen. In a pilot-scale operation, a subsurface flow constructed wetland (CW) consisted of a primary settlement tank, a trickling filter for pretreatment and two serially assembled basins. The trickling filter was ...
Yu Hongbo - - 2012
Context.-Several automated digital imaging systems have been introduced in recent years to improve turnaround time and proficiency in examining peripheral blood smears in hematology laboratories. Objective.-To evaluate a new automated digital imaging system, Nextslide Digital Review Network (Nextslide), for examination of peripheral blood smears. Design.-We evaluated 479 peripheral blood smears, ...
Samson Edward B - - 2012
Malaria affects over 200 million individuals annually, resulting in 800,000 fatalities. Current tests use blood smears and can only detect the disease when 0.1-1% of blood cells are infected. We are investigating the use of photoacoustic flowmetry to sense as few as one infected cell among 10 million or more ...
Lim C - - 2012
Centralised laboratories routinely determine blood types by serological and molecular methods. Current practices have limitations in terms of cost, time and accessibility. Miniaturised microfluidic platforms offer an alternative to conventional genotyping methods, since they consume fewer reagents, provide faster analysis and allow for complete integration and automation. As these 'lab-on-a-chip' ...
Rowland Kathryn J - - 2012
Massive small bowel resection (SBR) results in villus angiogenesis and a critical adaptation response within the remnant bowel. Previous ex vivo studies of intestinal blood flow after SBR are conflicting. We sought to determine the effect of SBR on intestinal hemodynamics using photoacoustic microscopy, a noninvasive, label-free, high-resolution in vivo ...
Zhang Zhang - - 2012
Coronary flow reserve (CFR) and fractional flow reserve (FFR) are important physiological indexes for coronary disease. The purpose of this study was to validate the CFR and FFR measurement techniques using only angiographic image data. Fifteen swine were instrumented with an ultrasound flow probe on the left anterior descending artery ...
Odenwald Tobias T Centre for Cardiovascular Imaging, UCL Institute of Cardiovascular Science & Great Ormond Street Hospital for Children, London, - - 2012
Systemic to pulmonary collaterals (SPCs) represent an additional and unpredictable source of pulmonary blood flow in patients with single ventricle physiology following bidirectional superior cavopulmonary connection (BCPC). Understanding their influence on patient outcomes has been hampered by uncertainty about the optimal method of quantifying SPC flow. To quantify SPC flow ...
Liao Lun-De LD National Chiao Tung University, Department of Electrical Engineering, Hsinchu, - - 2012
The specificity of the hemodynamic response function (HRF) is determined spatially by the vascular architecture and temporally by the evolution of hemodynamic changes. Here, we used functional photoacoustic microscopy (fPAM) to investigate single cerebral blood vessels of rats after left forepaw stimulation. In this system, we analyzed the spatiotemporal evolution ...
Greenberg Jacob A JA Department of Biology, University of New Mexico, Albuquerque, New Mexico 87131, - - 2012
We assessed the post-blood meal flight distance of four mosquito species in a unique environment using blood meal analysis. Mosquitoes were trapped at the Rio Grande Zoo in Albuquerque, NM, and the blood source of blood-engorged mosquitoes was identified. The distance from the enclosure of the animal serving as a ...
Cheng Ran - - 2012
Spontaneous low frequency oscillations (LFOs) around 0.1Hz have been observed in mean arterial pressure (MAP) and cerebral blood flow velocity (CBFV). Previous studies have shown that cerebral autoregulation in major arteries can be assessed by quantification of the phase shift between LFOs of MAP and CBFV. However, many cerebral diseases ...
Uhlmann Eric Luis - - 2012
Three empirical studies document the intuitive spillover of moral taint from a person who engages in immoral acts to another individual who is related by ties of blood kinship. In Study 1, participants were more likely to recommend that the biological grandchild of a wrongdoer, compared to a non-biological grandchild, ...
Liu Yupin - - 2012
A multitude of evidence suggests that iodinated contrast material causes nephrotoxicity; however, there have been no previous studies which use arterial spin labeling (ASL) blood flow magnetic resonance imaging (MRI) to investigate the alterations in effective renal plasma flow between normointensive and hypertensive rats following injection of contrast media. This ...
Fjeld Bente - - 2012
PURPOSE: Reanalyses are frequently requested in forensic toxicology, and knowledge of the stability of drugs in biological samples is of major importance for the interpretation of the toxicological findings. Currently, the literature on stability of gammahydroxybutyrate (GHB) in blood samples from living subjects and in post-mortem blood is limited. The ...
Nagamatsu Yoshinori - - 2012
Neutrophil elastase has been reported to play an important role in acute lung injury, which is a major cause of postoperative mortality after pulmonary resection. Neutrophil elastase released in the lungs reaches the peripheral circulation via the pulmonary veins. This study was performed to compare neutrophil elastase activity in pulmonary ...
Nchinda E C - - 2012
Background: Blood availability is an issue of concern in countries of sub-Saharan Africa where both the demand and discard rates of blood are high. Although some degree of attention is paid when transfusion reactions occur in recipients, no information is available on donor reactions in this setting. Objectives: This study ...
de Castro Therese - - 2012
Bloodstain pattern analysis (BPA) is the investigation and interpretation of blood deposited at crime scenes. However, the interaction of blood and apparel fabrics has not been widely studied. In this work, the development of bloodstains (passive, absorbed and transferred) dropped from three different heights (500, 1,000, 1,500 mm) on two cotton ...
Kiessling A-H - - 2012
Objectives: Haemodilution resulting from crystalloid priming of the cardiopulmonary bypass circuit represents a major risk factor for blood transfusions in high-risk cardiac surgery patients. We designed this study to evaluate the effects of antegrade autologous priming (AAP) on reducing perioperative blood transfusion and markers of the inflammatory response in older ...
Rhee Christopher J - - 2012
Hypotension and shock are risk factors for death, renal insufficiency, and stroke in preterm neonates. Goal-directed neonatal hemodynamic management lacks end-organ monitoring strategies to assess the adequacy of perfusion. Our aim is to develop a clinically viable, continuous metric of renovascular reactivity to gauge renal perfusion during shock. We present ...
Wang Xiaoqi X Department of Physics, Washington University in St. Louis, Saint Louis, MO 63110, - - 2013
Quantitative blood oxygenation level dependent technique provides an MRI-based method to measure tissue hemodynamic parameters such as oxygen extraction fraction and deoxyhemoglobin-containing (veins and prevenous part of capillaries) cerebral blood volume fraction. It is based on a theory of MR signal dephasing in the presence of blood vessel network and ...
Bhaskar Balu - - 2012
BACKGROUND: Despite the proven benefits in hemorrhagic shock, blood transfusions have been linked to increased morbidity and mortality. The short-term adverse effects of blood transfusion in cardiac surgical patients are well documented but there are very few studies that adequately assess the long-term survival. This study was undertaken to evaluate ...
Randriamanantany Z A - - 2012
This study assessed the phenotypic and allelic profiles of ABO and Rhesus D blood group system among first time blood donors at the National Centre of Blood Supply of Antananarivo. We collected through this retrospective study all data registered during 7 years of practice (from 2003 to 2009). Age and sex ...
Bajd Franci - - 2012
Objectives:  Outcome of the thrombolytic treatment is dependent on biochemical reactions of the fibrinolytic system as well as on hemodynamic conditions. However, understanding of the interaction between these two processes is still deficient. Methods:  Model blood clot thrombolysis in an artificial perfusion system, was studied by stroboscopic optical microscopy. The ...
Kubio Chrysantus - - 2012
BACKGROUND: Blood transfusion in rural sub-Saharan Africa presents special challenges. Transfusions are primarily given for emergencies-life-threatening blood loss or anemia; blood is usually collected from family or replacement donors; and facilities to store an adequate reserve in a hospital bank are constrained. We report the everyday and organizational practices in ...
Golan Lior - - 2012
Optical microscopy of blood cells in vivo provides a unique opportunity for clinicians and researchers to visualize the morphology and dynamics of circulating cells, but is usually limited by the imaging speed and by the need for exogenous labeling of the cells. Here we present a label-free approach for in ...
White Sean M SM Department of Biomedical Engineering, University of California, Irvine, CA 92697, - - 2012
The functionality of vascular networks within implanted prevascularized tissues is difficult to assess using traditional analysis techniques, such as histology. This is largely due to the inability to visualize hemodynamics in vivo longitudinally. Therefore, we have developed dynamic imaging methods to measure blood flow and hemoglobin oxygen saturation in implanted ...
Franchini M - - 2012
While a number of studies have analysed the relationship between ABO blood group and vascular thrombosis [1], especially venous thromboembolism (VTE) [2], only few data have been published on the association between ABO blood group and haemorrhagic disorders [3]. However, as plasma von Willebrand factor levels are 25-35 percent lower ...
Schytz Henrik W - - 2012
There is a need for real-time non-invasive, continuous monitoring of cerebral blood flow (CBF) during surgery, in intensive care units and clinical research. We investigated a new non-invasive hybrid technology employing ultrasound tagged near infrared spectroscopy (UT-NIRS) that may estimate changes in CBF using a cerebral blood flow index (CFI). ...
Clendenen Steven R - - 2012
BACKGROUND:: A persistent cerebrospinal fluid leak after spinal surgery can be associated with both meningitis and/or pneumocephalus. Therefore, early active intervention is recommended with surgical exploration, lumbar subarachnoid drain, and less commonly epidural blood patch. In the absence of a ligamentum flavum, the use of high-resolution ultrasound (US) spine imaging ...
Stark Heiko - - 2012
An interesting problem in hemorheology is to calculate that volume fraction of erythrocytes (hematocrit) that is optimal for transporting a maximum amount of oxygen. If the hematocrit is too low, too few erythrocytes are present to transport oxygen. If it is too high, the blood is very viscous and cannot ...
Higashi Haruhiko - - 2012
Adaptive servo ventilation (ASV) is reported to be effective for the treatment of heart failure. We treated a patient with idiopathic dilated cardiomyopathy using ASV and assessed the effects on hemodynamics, coronary flow, and flow reserve before and after ASV therapy. This case suggests that ASV might decrease myocardial oxygen ...
Zaouter Cédrick - - 2012
The pulse CO-oximeter (Rad-57 Masimo Corporation, Irvine, CA) allows non-invasive and instantaneous measurement of carboxyhemoglobin (COHb) and methemoglobin (MetHb) percentage level using a finger probe. However, the accuracy and reliability of the Rad-57 against the gold standard of venous or arterial blood samples have not been clearly established. Thus, the ...
Arnold Ryan C - - 2012
PURPOSE: Recent studies reported that microcirculatory blood flow alterations occur in patients with circulatory shock independent of arterial pressure but typically lack baseline microcirculatory data before the insult and after recovery. We selected cardiopulmonary bypass (CPB) patients with expected and rapidly reversible hemodynamic instability to test the hypothesis that microcirculatory ...
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