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Results 101 - 150 of 1831
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Li Cheng Guo - - 2012
The healthcare system relies widely on biochemical information obtained from blood sample extracted via hypodermic needles, despite the invasiveness and pain associated with this procedure. Therefore, an alternative micro-scale needle for minimally invasive blood sampling is highly desirable. Traditional fabrication techniques to create microneedles do not generate needles with the ...
Gao Lian - - 2012
A computer simulation model based on an analytic flow velocity distribution is proposed to generate Doppler ultrasound signals from pulsatile blood flow in the vessels with various stenosis degrees. The model takes into account the velocity field from pulsatile blood flow in the stenosed vessels, sample volume shape and acoustic ...
Lidsky Michael E - - 2012
OBJECTIVE: Vascular malformations are uncommon but may confer significant morbidity. Limitations in diagnosis and treatment result from inadequate classification schema and diagnostic algorithms. The crucial distinction is between high-flow and low-flow lesions because this informs prognosis and treatment. This study assessed the utility of dynamic contrast-enhanced magnetic resonance imaging (dceMRI) ...
Sumiyoshi Akira - - 2012
The effects of oxygen availability on neurovascular coupling were investigated using simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI), in addition to the monitoring of physiological parameters, in 16 α-chloralose-anesthetized rats. Mild hypoxic hypoxia (oxygen saturation=83.6±12.1%) induced significant reductions in fMRI responses (P<0.05) to electrical stimulation in the forepaw, ...
Blicher Jakob U JU Research Unit, Hammel Neurocentre, Aarhus University Hospital, Hammel, Denmark. - - 2012
Evaluation of cortical reorganization in chronic stroke patients requires methods to accurately localize regions of neuronal activity. Blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) is frequently employed; however, BOLD contrast depends on specific coupling relationships between the cerebral metabolic rate of oxygen (CMRO(2)), cerebral blood flow (CBF), and ...
Quantin C - - 2012
BACKGROUND: Obstetric hemorrhages are a frequent cause of maternal death all over the world, but are not routinely monitored. Health systems administrative databases could be used for this purpose, but data quality needs to be assessed. OBJECTIVES: Using blood transfusion data recorded in administrative databases to estimate the frequency of ...
Collins S L - - 2012
OBJECTIVES: Our current knowledge of the physiological dilatation of spiral arteries in pregnancy, is based on histology. Real-time ultrasound visualisation of these changes may aid understanding of abnormal placentation. This study aimed to investigate if changes in the spiral artery blood flow can be followed 'in vivo' and explore the novel ...
O'Neil Michael P - - 2012
BACKGROUND: Controversy exists regarding the optimal perfusion modality during cardiopulmonary bypass (CPB). Here we compare the effects of pulsatile versus nonpulsatile perfusion on microvascular blood flow during and after CPB. METHODS: High-risk cardiac surgical patients were randomly assigned to have pulsatile (n = 10) or nonpulsatile (n = 10) flow ...
Cornet E - - 2012
INTRODUCTION: The complete blood count (CBC) with differential leukocyte count (DIFF) is an important part of clinical laboratory analyses and provides crucial data for clinicians. Delivery time after blood collection and conditions of storage is known to affect the reliability of results of some hematologic parameters. The aim of this ...
Perinetti G - - 2012
Perinetti G, Di Leonardo B, Di Lenarda R, Contardo L. Repeatability of gingival crevicular fluid collection and quantification, as determined through its alkaline phosphatase activity: implications for diagnostic use. J Periodont Res 2012.doi: 10.1111/j.1600-0765.2012.01508.x. © 2012 John Wiley & Sons A/S Background and Objective:  In spite of four decades of ...
Jepsen Micha Phill Grønholm - - 2012
Transfusion transmitted malaria (TTM) in non-endemic countries is reduced by questioning blood donors and screening of donated blood. Conventional screening is performed by Indirect Fluorescence Antibody Test (IFAT). This method is manual and difficult to standardize. Here we study the diagnostic performance of a multiplex assay for detection of antibodies ...
Cowan Aimee Q - - 2012
Elevated blood viscosity is an integral component of vascular shear stress that contributes to the site specificity of atherogenesis, rapid growth of atherosclerotic lesions, and increases their propensity to rupture. Ex vivo measurements of whole blood viscosity (WBV) is a predictor of cardiovascular events in apparently healthy individuals and studies ...
Vonk Alexander B - - 2012
The study compared the effects of three blood concentration techniques after cardiopulmonary bypass on clinical hemostatic and ex-vivo rheological parameters. Residual blood of patients undergoing elective cardiac surgery was processed by centrifugation, cell salvage or ultrafiltration, and retransfused (nā€Š=ā€Š17 per group). Study parameters included blood loss, (free) hemoglobin, hematocrit, fibrinogen ...
Lo Lun-Chien - - 2012
In this study, a Pseudo three-dimensional Vision-based Nail-fold Morphological and Hemodynamic Analysis (PTVNMHA) is proposed to automatically extract morphological/hemodynamic features from a microscopic nail-fold image sequence, reconstruct the corresponding pseudo three-dimensional microvascular models, and visualize the dynamic blood flow in the model constructed. The morphological features extracted include the number, ...
Tasaki Tetsunori - - 2012
Little information is available regarding the influence of non-ionic low-osmolar iodinated contrast medium (CM) in stored blood on the quality of blood components. We sought to evaluate the quality of such CM-contaminated blood in terms of the degree of hemolysis, production of microaggregates, level of iodine concentration, and RBC shape, ...
Ha Hojin - - 2012
The micro-particle tracking velocimetry (μ-PTV) technique is used to obtain the velocity fields of blood flow in the microvasculature under in vivo conditions because it can provide the blood velocity distribution in microvessels with high spatial resolution. The in vivo μ-PTV technique usually requires a few to tens of seconds ...
Gimbrone Michael A MA Jr Center for Excellence in Vascular Biology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. - - 2013
The localization of atherosclerotic lesion formation to regions of disturbed blood flow associated with certain arterial geometries, in humans and experimental animals, suggests an important role for hemodynamic forces in the pathobiology of atherosclerosis. There is increasing evidence that the vascular endothelium, which is directly exposed to various fluid mechanical ...
Zhou Yimin - - 2012
Aim To investigate the clinical features and ultrasound imaging of placental site trophoblastic tumor(PSTT) Methods Fourteen cases of PSTT were collected for study, and the clinical features and transvaginal ultrasound imaging were investigated. Results The most frequent symptoms of PSTT were abnormal vaginal bleeding and amenorrhea. The interval time from ...
Hartung-Knemeyer Verena - - 2012
OBJECTIVE: Pre-therapeutic blood dosimetry prior to a high-dose radioiodine therapy (RAIT) is recommended and a blood dose of 2 Gy is considered to be safe. In this study, changes in the blood cell count after radioiodine therapy of high risk differentiated thyroid carcinoma (DTC) were analyzed and compared with the results ...
Sharma Parul - - 2012
For comparative evaluation, a real time PCR assay was standardized by using TaqMan primer and probe targeting the internal transcribed spacer 1 (ITS-1) region of rRNA for Trypanosoma evansi and sensitivity was evaluated by using DNA, extracted from diethyleamino ethane cellulose purified trypanosomes and trypanosomes infected whole blood of mice. ...
Schumacher Y O - - 2012
INTRODUCTION: Dehydration, fluid shifts or changes in coagulation occurring during air travel can trigger distinct reactions in the haematological system. Athletes are concerned that these effects might impair sporting performance, increase the risk of thrombosis or cause abnormalities in blood values that might be mistaken for doping in the 'Athlete's ...
Berg Mary - - 2012
Nearly one-quarter of the nation's blood supply is transfused to surgical patients. In many institutions, blood management programs that include autotransfusion (perioperative blood salvage) have been developed to decrease the need for allogeneic transfusion in eligible surgical patients. This article reviews management concepts related to an autotransfusion service.
Pinto Márcio - - 2012
BACKGROUND: The tests used for anemia screening in blood donors are based on fingerstick samples, leading to discomfort and complaints. The aim of this study was to analyze the feasibility of occlusion spectroscopy method in blood banks and to compare the method with fingerstick hemoglobinometer and hemoglobin (Hb) determination on ...
Ortigosa Cristiane - - 2012
Abstract Objectives: To determine the correlation between ph at birth and venous Doppler parameters in pregnancies with placental dysfunction. Methods: This was a prospective cohort study of 58 pregnancies with the diagnosis of placental dysfunction between 26 and 34 weeks of gestation. Inclusion criteria were singleton pregnancies, abnormal umbilical artery ...
Murata Daiki - - 2012
We hypothesized that semi-quantitative determinations of changeable blood flows in granulation and scar tissues during tendon healing could be helpful for differentiation between the acute phase rich in blood vessels and the remodeling phase with fewer vessels. Ten Thoroughbreds with injured superficial digital flexor tendon (SDFT) in a forelimb were ...
Guangjun Wang - - 2012
Abstract Objectives: The objective of this study was to investigate the change of mean blood flux in Hegu acupoint after contralateral Hegu acupoint was stimulated. Methods: Healthy volunteers (N=140) were placed in a temperature-controlled room as a resting state for 60 minutes. Then the measurements of skin blood flow were ...
Stansifer Kyle J - - 2012
OBJECTIVE: To describe and compare the intraoperative blood loss in children who underwent tonsillectomy and/or adenoidectomy during a transition from using electrocautery to a microdebrider. METHODS: Retrospective case series of a single pediatric otolaryngologist at an urban general hospital. Patients aged 2-20 years who had tonsillectomy, adenoidectomy, or adenotonsillectomy over ...
Heusch Philipp - - 2012
PURPOSE: To evaluate the impact of renal blood flow on apparent diffusion coefficients (ADC) and fractional anisotropy (FA) using time-resolved electrocardiogram (ECG)-triggered diffusion-tensor imaging (DTI) of the human kidneys. MATERIALS AND METHODS: DTI was performed in eight healthy volunteers (mean age 29.1 ± 3.2) using a single slice coronal echoplanar ...
van Kraaij Marian G J - - 2012
BACKGROUND: Since 2007, large outbreaks of Q fever occurred in the Netherlands. The unprecedented number of Q fever infections resulted in the need for the Dutch blood transfusion service to evaluate the risk of transmission of Coxiella burnetii via blood. STUDY DESIGN AND METHODS: A lookback procedure (recipient tracing) was performed for ...
Horstmann Wieger G - - 2012
Postoperative maintenance of high haemoglobin (Hb) levels and avoidance of homologous blood transfusions is important in total hip arthroplasty (THA). The introduction of a postoperative drainage autologous blood transfusion (ABT) system or no drainage following THA has resulted in reduction of homologous blood transfusion requirements compared with closed-suction drains. The ...
Bock Gregory L - - 2012
This paper explores the scriptural and theological reasons given by Jehovah's Witnesses (JWs) to refuse blood transfusions. Julian Savluescu and Richard W Momeyer argue that informed consent should be based on rational beliefs and that the refusal of blood transfusions by JWs is irrational, but after examining the reasons given ...
Quante Mirja - - 2012
BACKGROUND: The criteria for erythrocyte transfusion in stable premature infants are currently controversial. Haemodynamic measurements are not common in transfusion practice. The purpose of this study was to determine whether haemodynamic measurements could be helpful as objective criterion for transfusion decisions. We, therefore, evaluated clinical and haemodynamic changes in stable, ...
Kotani Yasuhiro - - 2012
BACKGROUND: This study evaluated the effect of a new measurement-superior vena cava (SVC) flow-and anatomic factors on postoperative arterial oxygen saturation and clinical outcome in patients who underwent bidirectional cavopulmonary shunt (BCPS). METHODS: We reviewed 19 patients who underwent a BCPS between January 2009 and May 2011 who also had ...
Kubota Keisuke - - 2012
The HyperEye Medical System is a newly developed device that allows for the visualization of the fluorescent image of indocyanine green enhanced by near-infrared light among the surrounding vivid color images. We recently applied this system to confirm the blood flow of an esophageal substitute, and for sentinel node navigation ...
Wang Ze Z Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. - - 2012
Denoising is critical to improving the quality and stability of cerebral blood flow (CBF) quantification in arterial spin labeled (ASL) perfusion magnetic resonance imaging (MRI) due to the intrinsic low signal-to-noise-ratio (SNR) of ASL data. Previous studies have been focused on reducing the spatial or temporal noise using standard filtering ...
Ene-Iordache Bogdan - - 2012
BackgroundEarly failure of the vascular access for haemodialysis (HD) after the surgical creation of a radial-cephalic arteriovenous fistula (AVF) occurs mainly due to a juxta-anastomotic stenosis. Even if elevated blood flow induces high wall shear stress, we have recently shown that disturbed flow, characterized by low and reciprocating flow, may ...
Songjaroen Temsiri - - 2012
A microfluidic paper-based analytical device (μPAD) for the separation of blood plasma from whole blood is described. The device can separate plasma from whole blood and quantify plasma proteins in a single step. The μPAD was fabricated using the wax dipping method, and the final device was composed of a ...
Ngai Shirley P C - - 2012
Abstract Objectives: Application of transcutaneous electrical nerve stimulation over acupuncture points (Acu-TENS) is a noninvasive intervention that has recently been shown to alleviate dyspnea in patients with stable chronic obstructive pulmonary disease (COPD). This case report aims to explore the role of Acu-TENS in patients diagnosed with COPD during the ...
Takuwa Hiroyuki - - 2012
Elucidating the mechanisms underlying the regulation of cerebral blood flow (CBF) is important to understanding the hemodynamic changes measured by positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) signals. The purpose of this study was to explore changes in hemodynamic characteristics during resting and sensory stimulation in awake ...
Rigby Lin - - 2012
LBH589 is one of the many histone deacetylase inhibitors (HDACi) that are currently in clinical trial. Despite their wide-spread use, there is little literature available describing the typical levels of histone acetylation in untreated peripheral blood, the treatment and storage of samples to retain optimal measurement of histone acetylation nor ...
Biancari Fausto - - 2012
BACKGROUND: Increased troponin levels after coronary artery bypass surgery are associated with increased risk of early and late mortality. We hypothesized that perioperative blood transfusion is associated with increased postoperative troponin release. METHODS: Complete data on perioperative blood transfusion and troponin I were available for 140 patients who underwent isolated, ...
Kim Yangho - - 2012
OBJECTIVES: We present data from the Korean National Health and Nutrition Examination Survey 2008-2009 regarding the association between blood lead and mercury levels and periodontitis in a representative sample of the adult South Korean population. METHODS: The analysis was restricted to participants ≥20 years of age who completed the health examination ...
Bugge H F - - 2012
Background and objectives  Severe anaemia is an important cause of mortality in developing countries. However, few studies have explored the use of and possibilities for blood transfusion services. The aims of this study are to explore the use of blood transfusion services at a hospital in sub-Saharan Africa and to ...
Bello G - - 2012
Severe sepsis and septic shock are still the leading cause of mortality and morbidity in the intensive care unit. The inflammatory response to infection is associated with an impressive, systemic release of pro- and antiinflammatory mediators, which results in generalized endothelial damage, multiple organ failure and altered cellular immunological responsiveness. ...
Bunck Alexander C - - 2012
PURPOSE: 4D phase contrast flow imaging is increasingly used to study the hemodynamics in various vascular territories and pathologies. The aim of this study was to assess the feasibility and validity of MRI based 4D phase contrast flow imaging for the evaluation of in-stent blood flow in 17 commonly used ...
Winch Peter D - - 2012
Many strategies, including intraoperative acute normovolemic hemodilution (ANH) and pharmacologic agents, exist to minimize the use of allogeneic blood products in pediatric congenital heart surgery. Recombinant activated factor VIIa (rFVIIa) is a hemostatic agent approved for the treatment of bleeding episodes and prevention of bleeding in surgical interventions in patients ...
Hambleton Victoria Lerma - - 2012
INTRODUCTION: Our aim was to evaluate the equivalence between analytic parameters from blood samples obtained from a saline solution lock device used for the infusion of drugs and those from venipuncture. In our emergency department, patients bearing a saline solution lock device have blood extracted by venipuncture to avoid possible ...
Perles-Barbacaru Adriana T - - 2012
This work demonstrates how the rapid steady state T(1) MRI technique for cerebral blood volume fraction (BVf) quantification can be used with intraperitoneal Gd-DOTA injections in mice at 4.7 T. The peak signal amplitude after intravenous administration (0.7 mmol/kg) and the steady state signal amplitude reached 15 min after intraperitoneal ...
Mendes Jason - - 2012
Magnetization prepared rapid acquisition gradient echo (3D MPRAGE) has been shown to be a sensitive method to image carotid intraplaque hemorrhage. As the MPRAGE sequence used to identify potential intraplaque hemorrhage does not utilize cardiac gating, it is difficult to optimize the inversion times due to the dynamic nature of ...
Yang Zhi-Gao - - 2012
Total knee arthroplasty is associated with substantial blood loss and the risks of transfusion. Conflicting reports have been published regarding the effectiveness and safety of tranexamic acid in reducing postoperative blood loss in total knee arthroplasty. We performed a meta-analysis to investigate the effectiveness and safety of tranexamic acid in ...
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