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Wu Tsung-Feng - - 2012
We demonstrated a unique optofluidic lab-on-a-chip device that can measure optically encoded forward scattering signals. From the design of the spatial pattern, we can measure the position and velocity of each cell in the flow and generate a 2-D cell distribution plot over the cross section of the channel. Moreover, ...
Santarcangelo Enrica L - - 2012
Abstract Mean values and the spectral variability of heart rate (HRV), blood pressure, and skin blood flow were studied in high and low hypnotizable subjects during simple relaxation. Similar subjective relaxation was reported by highs and lows. A parasympathetic prevalence (indicated by a higher High-Frequency component of HRV and a ...
Khoshrang Hossein - - 2013
Blood transfusion is an important part of the medical care service. As there has not been a regional study about blood requests for operations, this study was done to assess blood ordering for various types of elective urological surgery. In a descriptive, retrospective, cross-sectional study, blood requests for all patients ...
Kim Yangho - - 2012
INTRODUCTION: We present data from the Korean National Health and Nutrition Examination Survey 2008-2010 on the association between blood lead and hemoglobin levels in a representative sample of the adult South Korean population. METHODS: The analysis was restricted to participants ≥20 years of age who completed the health examination survey, including ...
Baskurt Oguz K - - 2012
It is well known that hemostatic-thrombotic mechanisms are influenced by hemodynamic factors, such as shear forces affecting platelets or red blood cell aggregation, in turn affecting flow in stenotic regions. Endothelial cell function is also significantly influenced by shear forces acting on the vessel wall. Further, the distribution of shear ...
Hu Lingzhi - - 2012
We present a novel blood flow-enhanced-saturation-recovery (BESR) sequence, which allows rapid in vivo T(1) measurement of blood for both (1) H and (19) F nuclei. BESR sequence is achieved by combining homogeneous spin preparation and time-of-flight image acquisition and therefore preserves high time efficiency and signal-to-noise ratio for (19) F ...
Soleimanifard Sahar - - 2012
In coronary magnetic resonance angiography, a magnetization-preparation scheme for T(2) -weighting (T(2) Prep) is widely used to enhance contrast between the coronary blood-pool and the myocardium. This prepulse is commonly applied without spatial selection to minimize flow sensitivity, but the nonselective implementation results in a reduced magnetization of the in-flowing ...
Wagner Marlies - - 2012
PURPOSE: To use T2'-mapping together with Pulsed Arterial Spin Labeling (PASL) providing quantitative information of deoxygenation level and cerebral blood flow (CBF) in the cerebral gray matter to obtain simultaneous information about the cerebral oxygen metabolism and the resulting cerebral vasoreactivity under normoxic and hyperoxic conditions. MATERIALS AND METHODS: Twelve ...
Shenkman Boris - - 2012
The relationship between tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA) function is not fully understood. The aim of this study was to compare in vitro the fibrinolytic activity of tPA and uPA and evaluate their possible interaction. Blood coagulation and fibrinolysis were conducted by rotation thromboelastometry, whereas blood ...
Garaci Francesco G - - 2012
Purpose:To investigate the relationship between chronic cerebrospinal venous insufficiency (CCSVI) and cerebral hemodynamic parameters and to disclose any possible involvement in the pathophysiology of multiple sclerosis (MS).Materials and Methods:The study was approved by the institutional review board, and written informed consent was obtained from all participants. The diagnosis of CCSVI ...
Pizov R - - 2012
BACKGROUND: /st>Variation in arterial pressure and plethysmographic waveforms has been shown to be predictors of cardiac output response to fluid challenge. The objective of this study was to evaluate the ability of arterial and plethysmographic waveform variables to predict hypotension during blood loss. METHODS: /st>Patients undergoing autologous haemodilution were studied. ...
Spector Sheldon Laurence - - 2012
Introduction. "Eosinophilic asthma" refers to an asthma phenotype characterized by predominance of eosinophils in the bronchial airways and corticosteroid responsiveness. Recent clinical trials of eosinophil-blocking agents have utilized a blood eosinophil count of 300 or 400 eosinophils/mm(3) or higher to identify subjects with moderate to severe asthma. We observed multiple ...
Lott Darline A - - 2012
Analytical base flow separation techniques are often used to determine the base flow contribution to total stream flow. Most analytical methods derive base flow from discharge records alone without using basin-specific variables other than basin area. This paper derives a power function for estimating base flow, the form being aQ(b) ...
Lee Gil Jun - - 2012
Oxygen has been widely used for chronic obstructive pulmonary disease (COPD) patients because long-term oxygen therapy (LTOT) can improve survival duration of COPD patients with severe hypoxemia. The typical oxygen delivery methods used for LTOT are continuous flow oxygen (CFO) and demand oxygen delivery (DOD). Currently, DOD is preferred to ...
Atlas Glen - - 2012
The esophageal Doppler monitor (EDM) is a minimally-invasive hemodynamic device which evaluates both cardiac output (CO), and fluid status, by estimating stroke volume (SV) and calculating heart rate (HR). The measurement of these parameters is based upon a continuous and accurate approximation of distal thoracic aortic blood flow. Furthermore, the ...
Magnussen K - - 2012
Background and Objectives  The literature contains little on the prevalence and causes of high predonation haemoglobin levels among blood donors. This study aimed to characterize and develop an algorithm to manage would-be donors with polycythaemia. Materials and Methods  Between November 2009 and November 2011, we offered haematology consultations to blood ...
Rajabi-Jagahrgh Ehsan E Mechanical Engineering Program, School of Dynamic Systems, University of Cincinnati, Cincinnati, Ohio, - - 2013
Arteriovenous fistula (AVF) nonmaturation is currently a significant clinical problem; however, the mechanisms responsible for this have remained unanswered. Previous work by our group and others has suggested that anatomical configuration and the corresponding hemodynamic endpoints could have an important role in AVF remodeling. Thus, our goal was to assess ...
Bächler Pablo - - 2012
OBJECTIVE: The purpose of this study was to analyze flow patterns in the pulmonary circulation of healthy volunteers by using 4D flow magnetic resonance imaging. MATERIALS AND METHODS: The study was approved by the local ethics committee and all subjects gave written informed consent. Eighteen volunteers underwent a 4D flow ...
Illies T - - 2012
BACKGROUND AND PURPOSE:4D MRA has been evolving as a noninvasive supplement for DSA. The purpose of this study was to evaluate the feasibility of a newly developed blood flow visualization technique for the classification of cerebral AVMs. We hypothesized that 4D-hMRA allows detection of different flow patterns within the nidus ...
Hitsumoto Takashi - - 2012
OBJECTIVES: Impairment of blood rheology has been reported to be associated with cardiovascular diseases. Recently, visible micro channel methods [micro channel array flow analyzer (MC-FAN)] have been developed to clinically evaluate blood rheology. The aim of this cross-sectional study is to clarify the factors important for impairment of blood rheology ...
Toth-Heyn Peter - - 2012
Sufficient organ blood flow of healthy newborn babies is maintained by relatively low systemic blood pressure. Premature infants are at an increased risk of systemic hypotension, often but not obviously, resulting in hypoperfusion of the cerebral, renal and intestinal vascular beds. Maintaining a stable blood pressure in preterm babies is ...
Ventura Walter - - 2012
OBJECTIVE: To explore the reliability of examining the external iliac artery (EIA) at 11+0 to 13+6 weeks of gestation with Doppler ultrasound and its relationship with maternal characteristics and uterine artery blood flow. STUDY DESIGN: Cross-sectional study of 451 pregnant women undergoing an ultrasound scan in the first trimester. Mean ...
Ercan Ertu Rul - - 2012
OBJECTIVE: Flow-mediated dilation (FMD) is used to evaluate endothelial functions. Computer-assisted analysis utilizing edge detection permits continuous measurements along the vessel wall. We have developed a new fully automated software program to allow accurate and reproducible measurement. METHODS: FMD has been measured and analyzed in 18 coronary artery disease (CAD) ...
Hutchison Joanna L JL School of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, TX 75080, - - 2013
The precise mechanisms that give rise to the blood-oxygen-level-dependent (BOLD) activation differences that accompany age-related cognitive slowing remain fundamentally unknown. We sought to isolate the origin of age-related BOLD changes by comparing blood-flow and oxygen-metabolic constituents of the BOLD response using dual-echo arterial spin labeling during visual stimulation and CO2 ...
Maunder C L - - 2012
OBJECTIVES: To assess the reliability of prothrombin time and activated partial thromboplastin time results generated from citrated whole blood samples following short-term storage at room temperature. METHODS: Clotting times were measured in blood samples from 40 dogs that showed a variety of clinical signs. Before measurement of prothrombin time and ...
Knobloch Verena - - 2012
Time-resolved three-dimensional flow measurements are limited by long acquisition times. Among the various acceleration techniques available, k-t methods have shown potential as they permit significant scan time reduction even with a single receive coil by exploiting spatiotemporal correlations. In this work, an extension of k-t principal component analysis is proposed ...
Detterich Jon J Division of Cardiology, Children's Hospital Los Angeles, California 90027, USA. - - 2013
Simple chronic transfusion therapy (CTT) is a mainstay for stroke prophylaxis in sickle cell anemia, but its effects on hemodynamics are poorly characterized. Transfusion improves oxygen-carrying capacity, reducing demands for high cardiac output. While transfusion decreases factors associated with vasoocclusion, including percent hemoglobin (Hb)S, reticulocyte count, and circulating cell-free Hb, ...
Stembirek J - - 2012
Many different surgical and non-surgical techniques are used for the treatment of temporomandibular joint (TMJ) hypermobility. One of these methods is autologous blood injection into the TMJ. The fate of the autologous blood used for treatment of recurring condylar dislocation is still not completely understood. The authors used 12 pigs ...
Grandahl Kasper - - 2012
International studies have shown blood lead at levels causing health concern in recreational indoor shooters. We hypothesized that Danish recreational indoor shooters would also have a high level of blood lead, and that this could be explained by shooting characteristics and the physical environment at the shooting range. This was ...
Sadeghian Mohammad Hadi - - 2012
BACKGROUND: The frequency of Human T lymphotropic Virus-1 (HTLV 1) is 2-3% in the general population and 0.7% in blood donors in northeast Iran. It is very important that we recognize the contributing factors in the pathogenesis of this virus. There are many reports that show that susceptibility to some ...
Massaú Aline - - 2012
This study investigates the frequency of Torque teno virus (TTV) infection in 150 blood donors and 77 patients requiring haemodialysis in southern Brazil. Plasma samples were screened for TTV DNA using polymerase chain reaction (PCR). The prevalences of TTV among blood donors and patients requiring haemodialysis were 73.3% and 68.8%, ...
Velden Joanne Van der - - 2012
ABSTRACT Background: Increases in blood vessel density and vascular area are now recognized as important features of remodeled airways in asthma. However, the time sequence for these vascular changes and whether they resolve in the absence of continued antigenic exposure is not well elucidated. The aim of the present study ...
Sørensen Henrik - - 2012
Perioperative optimization of spatially resolved near-infrared spectroscopy determined cerebral frontal lobe oxygenation (scO2) may reduce postoperative morbidity. Norepinephrine is routinely administered to maintain cerebral perfusion pressure and, thereby, cerebral blood flow, but norepinephrine reduces the scO2. We hypothesized that norepinephrine-induced reduction in scO2 is influenced by cutaneous vasoconstriction. Fifteen healthy ...
Granegger Marcus - - 2012
Estimation of instantaneous flow in rotary blood pumps (RBPs) is important for monitoring the interaction between heart and pump and eventually the ventricular function. Our group has reported an algorithm to derive ventricular contractility based on the maximum time derivative (dQ/dt(max) as a substitute for ventricular dP/dt(max) ) and pulsatility ...
He D - - 2012
What is believed to be the first fully integrated two-dimensional complementary metal oxide semiconductor (CMOS) imaging array for laser Doppler blood flow imaging is demonstrated. The sensor has 64×64 pixels and includes both analog and digital on-chip processing electronics. This offers several potential advantages over commercial sensors as the processing ...
Sobieski Michael A - - 2012
Mechanical circulatory assist devices that provide temporary support in heart failure patients are needed to enable recovery or provide a bridge to decision. Minimizing risk of blood damage (i.e., hemolysis) with these devices is critical, especially if the length of support needs to be extended. Hematologic responses of the RotaFlow ...
Koehn S - - 2012
The study aimed to examine 1) the validity of the nine-factor flow model in tennis competition; 2) differences in flow state between athletes who won or lost their competition match; 3) the link between flow and subjective performance; and 4) flow dimensions as predictors of performance outcome The sample consisted ...
Carroll Patrick D - - 2012
The development of anemia after birth in very premature, critically ill newborn infants is a universal well-described phenomenon. Although preventing anemia in this population, along with efforts to establish optimal red blood cell (RBC) transfusion and pharmacologic therapy continue to be actively investigated, the present review focuses exclusively on nonpharmacological ...
Gaynes Bruce - - 2012
To evaluate the feasibility of conjunctival hemodynamic measurements based on assessment of reproducibility, validity, and response to acute hypotension. Image sequences of the conjunctival microvasculature of rabbits were captured using a slit lamp biomicroscope under a steady-state condition, after topical administration of phenylephrine, and after intravenous administration of esmolol. Venous ...
Doctor Allan A Division of Pediatric Critical Care Medicine, Washington University School of Medicine, St Louis Children's Hospital, St Louis, MO 63110, USA. - - 2012
Red blood cell (RBC) transfusion is indicated to improve oxygen delivery to tissue, and for no other purpose. We have come to appreciate that donor RBCs are fundamentally altered during processing and storage in a manner that both impairs oxygen transport efficacy and introduces additional risk by perturbing both immune ...
Atasever BektaƟ - - 2012
BACKGROUND: After cardiac surgery, red blood cell (RBC) transfusion may improve systemic hemodynamics and thereby microvascular blood flow and O(2) delivery (DO(2) ). STUDY DESIGN AND METHODS: In a nonrandomized prospective observational study on post-cardiac surgery patients, systemic hemodynamics and microvascular blood flow, vascular density (sidestream dark-field imaging), hemoglobin (Hb) ...
Gonçalez Thelma T TT Blood Systems Research Institute, San Francisco, California; the Fundação Pró-Sangue Hemocentro de São Paulo, São Paulo, Brazil. - - 2013
The safety of the blood supply is ensured through several procedures from donor selection to testing of donated units. Examination of the donor deferrals at different centers provides insights into the role that deferrals play in transfusion safety. A cross-sectional descriptive study of prospective allogeneic blood donors at three large ...
Cheraghali A M - - 2012
Afghanistan is a country with population of over 28million. The long term conflicts have devastated country's qualified resources including human resources. ANBSTS was established by MoPH as the country national blood service. Currently in addition to central and regional blood centers of ANBSTS many other hospitals have their own transfusion ...
Shibata Masanori - - 2012
Blood color of dialysis patients can be seen routinely. Darkened blood color is often observed in critically ill patients generally because of decreased oxygen saturation, but little is known about the other factors responsible for the color intensity. In addition, quantitative blood color examination has not been performed yet. Therefore, ...
Gaddum Nicholas Richard NR Critical Care Research Group, The Prince Charles Hospital, Brisbane, Queensland, Australia. - - 2012
Long-term rotary left ventricular assist devices (LVADs) are increasingly employed to bridge patients with end-stage heart failure to transplant or as a destination therapy. Significant recent device development has increased patient support times, shifting further development focus toward physiologically sensitive control of the pump operation. Sensorless control of these devices ...
Meldal B H M - - 2012
Background and Objectives  Hepatitis E virus (HEV) infection is emerging as a potential new threat to blood safety after several cases of transfusion-transmission were reported from non-epidemic countries. On the basis of seroprevalence data, HEV is endemic in Ghana where poor sanitary conditions and regular flooding are prevalent. However, no ...
Gauthier Marianne - - 2012
To evaluate the sources of variation influencing the microvascularization parameters measured by dynamic contrast-enhanced ultrasonography (DCE-US). Firstly, we evaluated, in vitro, the impact of the manual repositioning of the ultrasound probe and the variations in flow rates. Experiments were conducted using a custom-made phantom setup simulating a tumor and its ...
Marshall Randolph S - - 2012
Cerebral hemodynamic impairment has come under examination over the years as an independent cause for cognitive dysfunction, but only recently has the advance of imaging and ultrasound technology permitted a fuller investigation of physiopathology. Beyond the impact of fixed structural lesions such as infarction and white matter hyperintensities, hemodynamic dysfunction, ...
De Backer Daniel - - 2012
One of the main goals of hemodynamic support is to preserve tissue perfusion. However issue perfusion is related more to microvascular perfusion than aortic blood flow. Monitoring the microcirculation has long been difficult. Recent technologic advances have made feasible monitoring of the microcirculation at bedside of critically ill patients. In ...
François Christopher J - - 2012
OBJECTIVE: The purpose of this study was to evaluate alterations in flow patterns in thoracic aortic dissections using 4-dimensional, flow-sensitive magnetic resonance imaging. METHODS: This prospective study was conducted at 2 academic tertiary referral medical centers. Thirteen 4-dimensional flow magnetic resonance imaging studies were performed in 12 subjects (4 female, ...
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