Search Results
Results 451 - 500 of 1842
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Leen Edward - - 2012
Imaging is key in the accurate monitoring of response to cancer therapies targeting tumour vascularity to inhibit its growth and dissemination. Dynamic contrast enhanced ultrasound (DCE ultrasound) is a quantitative method with the advantage of being non-invasive, widely available, portable, cost effective, highly sensitive and reproducible using agents that are ...
Severo Cátia B CB Exercise Pathophysiology Research Laboratory (LaFiEx) and Cardiology Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, - - 2013
The use of androgenic anabolic steroids (AAS) may be associated with changes in atherothrombotic markers and endothelial function. The purpose of this study was to compare atherothrombotic markers and endothelial function of AAS users and non-users. Cross-sectional study. Ten athletes who were users of AAS (confirmed by urine analysis) and ...
Sætre C - - 2012
Measurement of multiphase flow of gas, oil and water is not at all trivial and in spite of considerable achievements over the past two decades, important challenges remain (Corneliussen et al., 2005). These are related to reducing measurement uncertainties arising from variations in the flow regime, improving long term stability ...
Neale Joanne - - 2012
BACKGROUND: Although homelessness is a risk factor for HCV infection, there is a lack of research exploring the relationship between living in a hostel for homeless people and blood-borne viruses. The tendency to focus on risky injecting practices and HCV has also eclipsed the transmission risks potentially posed by spilt ...
Cai Kejia K Center for Magnetic Resonance and Optical Imaging, Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA. - - 2012
Clinically, development of anti-angiogenic drugs for cancer therapy is pivotal. Longitudinal monitoring of tumour angiogenesis can help clinicians determine the effectiveness of anti-angiogenic therapy. Blood oxygen level dependent (BOLD) effect has been widely used for functional imaging and tumour oxygenation assessment. In this study, the BOLD effect is investigated under ...
Yu Yang - - 2012
An ultrasonic flow meter for small pipes is presented. For metal pipe diameter smaller than 10 mm, clamp-on ultrasonic contrapropagation flow meters may encounter difficulties if cross talk or the short acoustic path contributes to large uncertainty in transit time measurement. Axial inline flow meters can avoid these problems, but ...
Sun Qi - - 2012
Purpose: Recently, image-based computational fluid dynamic (CFD) simulations have been proposed to investigate the local hemodynamics inside human cerebral aneurysms. It was suggested that the knowledge of the computed three-dimensional flow fields can be used to assist clinical risk assessment and treatment decision making. Therefore, it was desired to know ...
Zenchenko T A - - 2012
We analyze the results of daily laser Doppler flowmetry monitoring of blood microcirculation parameters in 9 healthy volunteers performed in 2006-2009. Dependence of microcirculation and BP parameters on geomagnetic activity was analyzed separately in each volunteer (the influence of ambient temperature was previously excluded). Significantly increased parameters of microcirculation in ...
Liu Han-Ping - - 2012
This study aimed to assess the specificity of auricular acupoints in responding to changes of qi and blood which, in traditional Chinese medicine, are considered as the fundamental substances in the human body for sustaining normal vital activity. A miniature fiber optic system was used to invasively measure the diffuse ...
Barth David - - 2012
In today's age of advanced technology used in the diagnosis of many medical problems, the blood film stands out as an inexpensive and quick diagnostic tool that can generally be performed in most laboratories. Understanding when to perform a blood film and how it is made and having an organized ...
Lemoult Grégoire - - 2012
We present an experimental study of the transition to turbulence in a plane Poiseuille flow. Using a well-controlled perturbation, we analyze the flow by using extensive particle image velocimetry and flow visualization (using laser-induced fluorescence) measurements, and use the deformation of the mean velocity profile as a criterion to characterize ...
Schmitges Jan - - 2012
To examine the homologous blood transfusion (HBT), autologous blood transfusion (ABT) and intraoperative blood conservation technique (IOBCT) rates and trends at open (ORP) and minimally invasive radical prostatectomy (MIRP). The Nationwide Inpatient Sample was queried. Multivariable logistic regression models focused on all three transfusion types. Covariables consisted of procedure specific ...
Sun Zi-Qiao - - 2012
This study presented the first in vivo animal experiments of using nano-cryosurgical modality to completely freezing tumor tissues embedded with large blood vessels, which is a tough issue to tackle otherwise. Three-dimensional theoretical simulations were also performed on the complex freezing problems by considering flow and heat transfer of blood ...
Vazquez Alberto L - - 2012
The dynamic properties of the cerebral metabolic rate of oxygen consumption (CMR(O2)) during changes in brain activity remain unclear. Therefore, the spatial and temporal evolution of functional increases in CMR(O2) was investigated in the rat somato-sensory cortex during forelimb stimulation under a suppressed blood flow response condition. Temporally, stimulation elicited ...
Moy Wesley J - - 2012
Current treatments of port-wine stain birthmarks typically involve use of a pulsed dye laser (PDL) combined with cooling of the skin. Currently, PDL therapy protocols result in varied success, as some patients experience complete blanching, while others do not. Over the past decade, we have studied the use of photodynamic ...
Elgendi Mohamed - - 2012
Photoplethysmography (PPG) is used to estimate the skin blood flow using infrared light. Researchers from different domains of science have become increasingly interested in PPG because of its advantages as non-invasive, inexpensive, and convenient diagnostic tool. Traditionally, it measures the oxygen saturation, blood pressure, cardiac output, and for assessing autonomic ...
Das L K - - 2012
This study was focussed on identifying a cost-effective method for delimitation, monitoring and evaluation in bancroftian filariasis. Finger prick blood samples were collected between 20.00 and 23.00 hours for the detection of microfilariae (mf) from the available population in a village which was endemic for lymphatic filariasis. Simultaneously, from each ...
Mandak Jiri - - 2012
Aim. The aim of this study was to compare the impact of standard cardiopulmonary bypass (CPB) with mini CPB on peripheral tissue perfusion. Methods. 24 patients with ischemic heart disease scheduled for CPB were randomised to two groups: Group A (12 patients, standard CPB) and Group B (12 patients, mini ...
Pichler Gerhard - - 2012
C reactive protein (CRP) is a sensitive marker of acute inflammation of infectious and non-infectious origin. Aim was to use near-infrared spectroscopy (NIRS) to analyse peripheral oxygenation and perfusion in term and preterm neonates with elevated CRP levels, at a time when routine haemodynamic variables are still normal. Prospective observational ...
Colquhoun Douglas A - - 2012
The ability of practitioners to assess the adequacy of global oxygen delivery is dependent on an accurate measurement of central venous saturation. Traditional techniques require the placement of invasive central venous access devices. This study aimed to compare two non-invasive technologies for the estimation of regional venous saturation (reflectance plethysmography ...
Genét Gustav Folmer - - 2012
Background: Rapid identification of clinically relevant coagulopathies in, acute coagulopathy of trauma shock (ACOTS) has led to the development of faster point-of-care viscoelastic whole-blood-based tests like rapid thrombelastography (RapidTEG). The sensitivity of RapidTEG to detect hyperfibrinolysis, as compared to standard KaolinTEG, is unknown. To investigate this, the ability of RapidTEG, ...
Stramer Susan L - - 2012
There have been anecdotal reports of influenza viremia since the 1960s. We present an assessment of the prevalence of seasonal and 2009 H1N1 influenza viremia (via RNA testing) in blood donor populations using multiple sensitive detection assays. Several influenza RNA amplification assays, including transcription-mediated amplification (TMA) and 2 reverse-transcription polymerase ...
Varela Marta M Imaging Sciences Department, Imperial College London, London, - - 2012
Alterations in cerebral blood flow (CBF) are believed to be linked to many of the neurological pathologies that affect neonates and small infants. CBF measurements are nonetheless often difficult to perform in this population, as many techniques rely on radioactive tracers or other invasive methods. In this study, mean global ...
Ciarrocca Manuela - - 2012
OBJECTIVES: This is the first research study to compare among female, non-smoker workers: (a) the exposure to benzene, toluene and xylenes (BTXs) in urban air during work in the street (traffic policewomen, TP) vs. work in vehicles (police drivers, PD); (b) the exposure to BTXs in urban environments (in street ...
Borges Boniek Castillo Dutra - - 2012
Abstract Aim. This study aimed to characterize the morphology of filler particles and to analyze the effect of shortened and extended photoactivation times on hardness (VHN) and cross-link density (CLD) of resin-based low-viscosity materials. Methods. Sixteen commercially available materials were tested: four fissure sealants (Alpha Seal, Fluroshield Yellowed, Bioseal and ...
Domoki Ferenc - - 2012
A new laser speckle-contrast analysis (LASCA) technique based on multi-exposure imaging was employed to simultaneously study pial arteriolar responses with cerebrocortical perfusion changes to various vasodilator (5-10% CO(2) ventilation, bradykinin (1-10μM), N-methyl-d-aspartate (100μM)) vasoconstrictor (10-100μM noradrenaline, 1M KCl), or neutral (2.1% H(2) ventilation) stimuli as well as to asphyxia in ...
Al-Khazraji Baraa K - - 2012
Objectives:  1) Develop a valid experimental method for quantifying blood flow in continuously branching skeletal muscle arterioles, and 2) derive an empirical relationship between velocity ratio (V(Max) /V(Mean) ) and arteriolar diameter. Methods:  We evaluated arteriolar trees using intravital video microscopy of rat gluteus maximus muscle and developed a method ...
Heggelund Julie E - - 2012
Cholera is a disease which shows a clear blood group profile, with blood group O individuals experiencing the most severe symptoms. For a long time, the cholera toxin has been suspected to be the main culprit of this blood group dependence. Here, we show that both El Tor and classical ...
Xydas Steve - - 2012
OBJECTIVE: The study objective was to determine the effects of implementing a blood conservation algorithm on blood product use and outcomes in a community cardiac surgery program. METHODS: A blood management strategy including lower hemoglobin transfusion threshold and algorithm-driven decisions was adopted. Intraoperatively, point-of-care testing was used to avoid inappropriate ...
Celere M S - - 2012
Objective: Evaluation of the antimicrobial effect of skin disinfection techniques is essential to avoid the transmission of infectious agents during blood transfusion. The aim of this study was to examine the effectiveness of two methods of arm skin disinfection used in blood donors at a Hemotherapy Center in Brazil that ...
Skogstrand Kristin K Department of Clinical Biochemistry and Immunology, Statens Serum Institut, Copenhagen, Denmark. - - 2012
In vitro stimulation of whole blood or isolated blood cells with specific antigens is used for several purposes. Immediately following incubation with antigens, samples have to be centrifuged to stop the reactions by remaining cells and the supernatant refrigerated or analysed directly to preserve the analytes of interest, which makes ...
Wang Yuedong - - 2012
BACKGROUND: Intraoperative blood salvage can reduce or avoid perioperative allogeneic blood transfusion. Salvaging the blood in the portal hypertension-induced enlarged spleen becomes an issue of concern during devascularization surgery because an enlarged spleen accommodates a large red cell pool. We report 20 cases of laparoscopic splenectomy and azygoportal disconnection and ...
Wehrli Gay - - 2012
Therapeutic Apheresis Medicine Services work closely with Blood Banking and Transfusion Medicine Services (BBTMS). The BBTMS performs patient testing and provides blood components for patients undergoing therapeutic apheresis procedures. This article will provide an overview of blood component descriptions, patient testing, and blood component options and preparations for therapeutic apheresis ...
Järhult Susann J - - 2012
Background:  Systolic to diastolic blood flow velocity (SDFV) ratio in the brachial artery recently proved to be related to cardiovascular risk and carotid atherosclerosis. We hypothesized that the SDFV ratio was related to established markers of vascular function and global atherosclerosis. Methods:  Established markers of endothelial function in forearm resistance ...
Shenkman Boris - - 2012
Glanzmann's thrombasthenia (GT) is characterized by increased bleeding risk. The treatment options in GT are limited. The aim of this study was to test the effect of GT blood supplementation with fibrinogen and factor XIII on thrombin generation, blood clotting, and fibrinolysis. Whole blood samples of GT patients and normal ...
Roca-Tey Ramón - - 2012
Purpose: To report experience over five years of vascular access (VA) stenosis surveillance. Methods: We prospectively monitored the blood flow rate (QA) of 145 VA in 131 ESRD (age 62.6 ±13.5 y) patients (pts). QA measurement: within the first hour of the hemodialysis (HD) session by the Delta-H method using ...
Davidson Josy - - 2012
BACKGROUND: Oxygen therapy is an important therapeutic resource for patients with hypoxemia. When changing oxygen flowmeters, we have observed that sometimes even with the same oxygen flow setting as before, a different pulse oxygen saturation is obtained. OBJECTIVE: To analyze the precision and accuracy of flowmeters used in hospital settings. ...
Kneubuehl Beat P - - 2012
When analysing blood spatters, traces often occur which regarding the collision angle, cannot be allocated to any supposed centre of origin. Drops following highly curved (ballistic) trajectories usually form these types of traces. The reconstruction of such trajectories requires knowledge of the mass, the diameter (of which approximations are known) ...
Carhart-Harris Robin L RL Neuropsychopharmacology Unit, University of Bristol, Bristol BS8 2BN, United - - 2012
Psychedelic drugs have a long history of use in healing ceremonies, but despite renewed interest in their therapeutic potential, we continue to know very little about how they work in the brain. Here we used psilocybin, a classic psychedelic found in magic mushrooms, and a task-free functional MRI (fMRI) protocol ...
Bahra M M William Harvey Research Institute, Centre for Clinical Pharmacology, Barts & the London School of Medicine and Dentistry, Queen Mary University of London, London, United - - 2012
Ingestion of inorganic nitrate elevates blood and tissue levels of nitrite via bioconversion in the entero-salivary circulation. Nitrite is converted to NO in the circulation, and it is this phenomenon that is thought to underlie the beneficial effects of inorganic nitrate in humans. Our previous studies have demonstrated that oral ...
Mandeville Joseph B JB MGH/MIT/HMS Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA. - - 2012
Changes in cerebral blood volume (CBV) and blood magnetization each induce changes in the transverse relaxation rate of MRI signal that are associated with changes in cerebral activity. BOLD signal, the preeminent method for non-invasive localization of task-induced brain function in human subjects, reflects a combination of changes in CBV ...
Huisman Sander G - - 2012
The flow structure of strongly turbulent Taylor-Couette flow with Reynolds numbers up to Re_{i}=2×10^{6} of the inner cylinder is experimentally examined with high-speed particle image velocimetry (PIV). The wind Reynolds numbers Re_{w} of the turbulent Taylor-vortex flow is found to scale as Re_{w}∝Ta^{1/2}, exactly as predicted by Grossmann and Lohse ...
Dong Lixin - - 2012
This study explored using a novel diffuse correlation spectroscopy (DCS) flow-oximeter to noninvasively monitor blood flow and oxygenation changes in head and neck tumors during radiation delivery. A fiber-optic probe connected to the DCS flow-oximeter was placed on the surface of the radiologically/clinically involved cervical lymph node. The DCS flow-oximeter ...
Van Kruchten Roger - - 2012
Custom-made and commercial parallel-plate flow chambers are widely used for studies of platelet activation and thrombus formation in whole blood at defined shear rates. When used in a reproducible way, such flow chamber devices give valuable information on the thrombogenic potential of human, mouse, or rat blood. This article aims ...
Wolf Stefan - - 2012
Since its introduction into clinical practice, the Bowman Hemedex® regional cerebral blood flow (CBF) monitor has provided a valuable tool for the bedside assessment of CBF in neurointensive care. The purpose of our study was to estimate the accuracy of CBF measurements between automatically performed self-calibration cycles at regular intervals. ...
Dyson Rebecca M - - 2012
Introduction:Microvascular dysfunction, characterized by inappropriate vasodilatation and high blood flow in the peripheral microcirculation, is linked to physiologic instability and poor outcome in neonates. Specifically, preterm neonates have significantly higher levels of baseline microvascular blood flow than term neonates at 24 h postnatal age. Because of similarities between human and ...
Kumbasar Karaosmanoglu Hayat - - 2012
In this study, we aimed to compare the HBV seroprevalances of voluntary blood donors and the healthy persons who required premarital screening. HBsAg ELISA results were collected retrospectively from the records of 9,949 blood donors and 954 healthy persons who required premarital screening. HBsAg was detected in 182 of 9,949 (%1.8) ...
Chou Wen-Cheng - - 2012
According to the principles of traditional Chinese medicine, channels and collaterals within the body provide pathways through which qi and blood travel, and each channel or collateral is linked with a specific organ. The Yinlingquan (spleen 9, SP9) and Ququan (liver 8, LR8) acupoints represent the sea points of the ...
Collopy Kevin T - - 2012
The administration of oxygen is safe and effective for patients who are in respiratory distress or who are hypoxic. Never feel that oxygen needs to be withheld. However, keep in mind that there are real consequences to the long-term utilization of high-flow oxygen. To help prevent potential complications from oxygen ...
Christensen Dawn M - - 2012
The use of mechanical pumps for circulatory support started in the mid-1950s. The evolution of these devices has led to the present-day use of continuous-flow pumps to take over the function of a patient's failing heart. The physiology associated with rotary blood pump use is quite different from normal cardiovascular ...
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