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Results 451 - 500 of 1845
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Blasi Annabel - - 2012
BACKGROUND: Rotation thromboelastometry (TEM) has been proposed as a convenient alternative to standard coagulation tests in guiding the treatment of coagulopathy during orthotopic liver transplantation (OLT). This study was aimed at assessing the value of TEM in monitoring blood coagulation and guide transfusion support in OLT. STUDY DESIGN AND METHODS: ...
Roca-Tey Ramon - - 2012
Introduction. Periodic blood flow (QA) measurement is the preferred way for arteriovenous fistula (AVF) surveillance in chronic hemodialysis (HD) patients. Objectives. 1) Assess the efficacy of the temperature gradient method (TGM) on the QA determinations using the Twister&trade; device and to compare the functional results with the Delta-H method. 2) ...
Sogawa Kenji - - 2012
PURPOSE: To investigate the relationship between the choroidal thickness and choroidal blood flow in healthy young subjects. DESIGN: Retrospective, cross-sectional study. METHODS: We examined 25 eyes of 25 healthy young Japanese subjects. The subfoveal choroidal thickness was measured by enhanced depth imaging optical coherence tomography (EDI-OCT). The total choroidal blood ...
Severo Cátia B CB Exercise Pathophysiology Research Laboratory (LaFiEx) and Cardiology Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, - - 2013
The use of androgenic anabolic steroids (AAS) may be associated with changes in atherothrombotic markers and endothelial function. The purpose of this study was to compare atherothrombotic markers and endothelial function of AAS users and non-users. Cross-sectional study. Ten athletes who were users of AAS (confirmed by urine analysis) and ...
Leen Edward - - 2012
Imaging is key in the accurate monitoring of response to cancer therapies targeting tumour vascularity to inhibit its growth and dissemination. Dynamic contrast enhanced ultrasound (DCE ultrasound) is a quantitative method with the advantage of being non-invasive, widely available, portable, cost effective, highly sensitive and reproducible using agents that are ...
Neale Joanne - - 2012
BACKGROUND: Although homelessness is a risk factor for HCV infection, there is a lack of research exploring the relationship between living in a hostel for homeless people and blood-borne viruses. The tendency to focus on risky injecting practices and HCV has also eclipsed the transmission risks potentially posed by spilt ...
Sætre C - - 2012
Measurement of multiphase flow of gas, oil and water is not at all trivial and in spite of considerable achievements over the past two decades, important challenges remain (Corneliussen et al., 2005). These are related to reducing measurement uncertainties arising from variations in the flow regime, improving long term stability ...
Cai Kejia K Center for Magnetic Resonance and Optical Imaging, Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA. - - 2012
Clinically, development of anti-angiogenic drugs for cancer therapy is pivotal. Longitudinal monitoring of tumour angiogenesis can help clinicians determine the effectiveness of anti-angiogenic therapy. Blood oxygen level dependent (BOLD) effect has been widely used for functional imaging and tumour oxygenation assessment. In this study, the BOLD effect is investigated under ...
Schmitges Jan - - 2012
To examine the homologous blood transfusion (HBT), autologous blood transfusion (ABT) and intraoperative blood conservation technique (IOBCT) rates and trends at open (ORP) and minimally invasive radical prostatectomy (MIRP). The Nationwide Inpatient Sample was queried. Multivariable logistic regression models focused on all three transfusion types. Covariables consisted of procedure specific ...
Sun Qi - - 2012
Purpose: Recently, image-based computational fluid dynamic (CFD) simulations have been proposed to investigate the local hemodynamics inside human cerebral aneurysms. It was suggested that the knowledge of the computed three-dimensional flow fields can be used to assist clinical risk assessment and treatment decision making. Therefore, it was desired to know ...
Lemoult Grégoire - - 2012
We present an experimental study of the transition to turbulence in a plane Poiseuille flow. Using a well-controlled perturbation, we analyze the flow by using extensive particle image velocimetry and flow visualization (using laser-induced fluorescence) measurements, and use the deformation of the mean velocity profile as a criterion to characterize ...
Barth David - - 2012
In today's age of advanced technology used in the diagnosis of many medical problems, the blood film stands out as an inexpensive and quick diagnostic tool that can generally be performed in most laboratories. Understanding when to perform a blood film and how it is made and having an organized ...
Moy Wesley J - - 2012
Current treatments of port-wine stain birthmarks typically involve use of a pulsed dye laser (PDL) combined with cooling of the skin. Currently, PDL therapy protocols result in varied success, as some patients experience complete blanching, while others do not. Over the past decade, we have studied the use of photodynamic ...
Sun Zi-Qiao - - 2012
This study presented the first in vivo animal experiments of using nano-cryosurgical modality to completely freezing tumor tissues embedded with large blood vessels, which is a tough issue to tackle otherwise. Three-dimensional theoretical simulations were also performed on the complex freezing problems by considering flow and heat transfer of blood ...
Liu Han-Ping - - 2012
This study aimed to assess the specificity of auricular acupoints in responding to changes of qi and blood which, in traditional Chinese medicine, are considered as the fundamental substances in the human body for sustaining normal vital activity. A miniature fiber optic system was used to invasively measure the diffuse ...
Vazquez Alberto L - - 2012
The dynamic properties of the cerebral metabolic rate of oxygen consumption (CMR(O2)) during changes in brain activity remain unclear. Therefore, the spatial and temporal evolution of functional increases in CMR(O2) was investigated in the rat somato-sensory cortex during forelimb stimulation under a suppressed blood flow response condition. Temporally, stimulation elicited ...
Zenchenko T A - - 2012
We analyze the results of daily laser Doppler flowmetry monitoring of blood microcirculation parameters in 9 healthy volunteers performed in 2006-2009. Dependence of microcirculation and BP parameters on geomagnetic activity was analyzed separately in each volunteer (the influence of ambient temperature was previously excluded). Significantly increased parameters of microcirculation in ...
Yu Yang - - 2012
An ultrasonic flow meter for small pipes is presented. For metal pipe diameter smaller than 10 mm, clamp-on ultrasonic contrapropagation flow meters may encounter difficulties if cross talk or the short acoustic path contributes to large uncertainty in transit time measurement. Axial inline flow meters can avoid these problems, but ...
Elgendi Mohamed - - 2012
Photoplethysmography (PPG) is used to estimate the skin blood flow using infrared light. Researchers from different domains of science have become increasingly interested in PPG because of its advantages as non-invasive, inexpensive, and convenient diagnostic tool. Traditionally, it measures the oxygen saturation, blood pressure, cardiac output, and for assessing autonomic ...
Colquhoun Douglas A - - 2012
The ability of practitioners to assess the adequacy of global oxygen delivery is dependent on an accurate measurement of central venous saturation. Traditional techniques require the placement of invasive central venous access devices. This study aimed to compare two non-invasive technologies for the estimation of regional venous saturation (reflectance plethysmography ...
Genét Gustav Folmer - - 2012
Background: Rapid identification of clinically relevant coagulopathies in, acute coagulopathy of trauma shock (ACOTS) has led to the development of faster point-of-care viscoelastic whole-blood-based tests like rapid thrombelastography (RapidTEG). The sensitivity of RapidTEG to detect hyperfibrinolysis, as compared to standard KaolinTEG, is unknown. To investigate this, the ability of RapidTEG, ...
Pichler Gerhard - - 2012
C reactive protein (CRP) is a sensitive marker of acute inflammation of infectious and non-infectious origin. Aim was to use near-infrared spectroscopy (NIRS) to analyse peripheral oxygenation and perfusion in term and preterm neonates with elevated CRP levels, at a time when routine haemodynamic variables are still normal. Prospective observational ...
Das L K - - 2012
This study was focussed on identifying a cost-effective method for delimitation, monitoring and evaluation in bancroftian filariasis. Finger prick blood samples were collected between 20.00 and 23.00 hours for the detection of microfilariae (mf) from the available population in a village which was endemic for lymphatic filariasis. Simultaneously, from each ...
Mandak Jiri - - 2012
Aim. The aim of this study was to compare the impact of standard cardiopulmonary bypass (CPB) with mini CPB on peripheral tissue perfusion. Methods. 24 patients with ischemic heart disease scheduled for CPB were randomised to two groups: Group A (12 patients, standard CPB) and Group B (12 patients, mini ...
Stramer Susan L - - 2012
There have been anecdotal reports of influenza viremia since the 1960s. We present an assessment of the prevalence of seasonal and 2009 H1N1 influenza viremia (via RNA testing) in blood donor populations using multiple sensitive detection assays. Several influenza RNA amplification assays, including transcription-mediated amplification (TMA) and 2 reverse-transcription polymerase ...
Varela Marta M Imaging Sciences Department, Imperial College London, London, - - 2012
Alterations in cerebral blood flow (CBF) are believed to be linked to many of the neurological pathologies that affect neonates and small infants. CBF measurements are nonetheless often difficult to perform in this population, as many techniques rely on radioactive tracers or other invasive methods. In this study, mean global ...
Borges Boniek Castillo Dutra - - 2012
Abstract Aim. This study aimed to characterize the morphology of filler particles and to analyze the effect of shortened and extended photoactivation times on hardness (VHN) and cross-link density (CLD) of resin-based low-viscosity materials. Methods. Sixteen commercially available materials were tested: four fissure sealants (Alpha Seal, Fluroshield Yellowed, Bioseal and ...
Ciarrocca Manuela - - 2012
OBJECTIVES: This is the first research study to compare among female, non-smoker workers: (a) the exposure to benzene, toluene and xylenes (BTXs) in urban air during work in the street (traffic policewomen, TP) vs. work in vehicles (police drivers, PD); (b) the exposure to BTXs in urban environments (in street ...
Heggelund Julie E - - 2012
Cholera is a disease which shows a clear blood group profile, with blood group O individuals experiencing the most severe symptoms. For a long time, the cholera toxin has been suspected to be the main culprit of this blood group dependence. Here, we show that both El Tor and classical ...
Domoki Ferenc - - 2012
A new laser speckle-contrast analysis (LASCA) technique based on multi-exposure imaging was employed to simultaneously study pial arteriolar responses with cerebrocortical perfusion changes to various vasodilator (5-10% CO(2) ventilation, bradykinin (1-10μM), N-methyl-d-aspartate (100μM)) vasoconstrictor (10-100μM noradrenaline, 1M KCl), or neutral (2.1% H(2) ventilation) stimuli as well as to asphyxia in ...
Al-Khazraji Baraa K - - 2012
Objectives:  1) Develop a valid experimental method for quantifying blood flow in continuously branching skeletal muscle arterioles, and 2) derive an empirical relationship between velocity ratio (V(Max) /V(Mean) ) and arteriolar diameter. Methods:  We evaluated arteriolar trees using intravital video microscopy of rat gluteus maximus muscle and developed a method ...
Xydas Steve - - 2012
OBJECTIVE: The study objective was to determine the effects of implementing a blood conservation algorithm on blood product use and outcomes in a community cardiac surgery program. METHODS: A blood management strategy including lower hemoglobin transfusion threshold and algorithm-driven decisions was adopted. Intraoperatively, point-of-care testing was used to avoid inappropriate ...
Skogstrand Kristin K Department of Clinical Biochemistry and Immunology, Statens Serum Institut, Copenhagen, Denmark. - - 2012
In vitro stimulation of whole blood or isolated blood cells with specific antigens is used for several purposes. Immediately following incubation with antigens, samples have to be centrifuged to stop the reactions by remaining cells and the supernatant refrigerated or analysed directly to preserve the analytes of interest, which makes ...
Celere M S - - 2012
Objective: Evaluation of the antimicrobial effect of skin disinfection techniques is essential to avoid the transmission of infectious agents during blood transfusion. The aim of this study was to examine the effectiveness of two methods of arm skin disinfection used in blood donors at a Hemotherapy Center in Brazil that ...
Wang Yuedong - - 2012
BACKGROUND: Intraoperative blood salvage can reduce or avoid perioperative allogeneic blood transfusion. Salvaging the blood in the portal hypertension-induced enlarged spleen becomes an issue of concern during devascularization surgery because an enlarged spleen accommodates a large red cell pool. We report 20 cases of laparoscopic splenectomy and azygoportal disconnection and ...
Wehrli Gay - - 2012
Therapeutic Apheresis Medicine Services work closely with Blood Banking and Transfusion Medicine Services (BBTMS). The BBTMS performs patient testing and provides blood components for patients undergoing therapeutic apheresis procedures. This article will provide an overview of blood component descriptions, patient testing, and blood component options and preparations for therapeutic apheresis ...
Shenkman Boris - - 2012
Glanzmann's thrombasthenia (GT) is characterized by increased bleeding risk. The treatment options in GT are limited. The aim of this study was to test the effect of GT blood supplementation with fibrinogen and factor XIII on thrombin generation, blood clotting, and fibrinolysis. Whole blood samples of GT patients and normal ...
Järhult Susann J - - 2012
Background:  Systolic to diastolic blood flow velocity (SDFV) ratio in the brachial artery recently proved to be related to cardiovascular risk and carotid atherosclerosis. We hypothesized that the SDFV ratio was related to established markers of vascular function and global atherosclerosis. Methods:  Established markers of endothelial function in forearm resistance ...
Kneubuehl Beat P - - 2012
When analysing blood spatters, traces often occur which regarding the collision angle, cannot be allocated to any supposed centre of origin. Drops following highly curved (ballistic) trajectories usually form these types of traces. The reconstruction of such trajectories requires knowledge of the mass, the diameter (of which approximations are known) ...
Roca-Tey Ramón - - 2012
Purpose: To report experience over five years of vascular access (VA) stenosis surveillance. Methods: We prospectively monitored the blood flow rate (QA) of 145 VA in 131 ESRD (age 62.6 ±13.5 y) patients (pts). QA measurement: within the first hour of the hemodialysis (HD) session by the Delta-H method using ...
Carhart-Harris Robin L RL Neuropsychopharmacology Unit, University of Bristol, Bristol BS8 2BN, United - - 2012
Psychedelic drugs have a long history of use in healing ceremonies, but despite renewed interest in their therapeutic potential, we continue to know very little about how they work in the brain. Here we used psilocybin, a classic psychedelic found in magic mushrooms, and a task-free functional MRI (fMRI) protocol ...
Davidson Josy - - 2012
BACKGROUND: Oxygen therapy is an important therapeutic resource for patients with hypoxemia. When changing oxygen flowmeters, we have observed that sometimes even with the same oxygen flow setting as before, a different pulse oxygen saturation is obtained. OBJECTIVE: To analyze the precision and accuracy of flowmeters used in hospital settings. ...
Bahra M M William Harvey Research Institute, Centre for Clinical Pharmacology, Barts & the London School of Medicine and Dentistry, Queen Mary University of London, London, United - - 2012
Ingestion of inorganic nitrate elevates blood and tissue levels of nitrite via bioconversion in the entero-salivary circulation. Nitrite is converted to NO in the circulation, and it is this phenomenon that is thought to underlie the beneficial effects of inorganic nitrate in humans. Our previous studies have demonstrated that oral ...
Mandeville Joseph B JB MGH/MIT/HMS Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA. - - 2012
Changes in cerebral blood volume (CBV) and blood magnetization each induce changes in the transverse relaxation rate of MRI signal that are associated with changes in cerebral activity. BOLD signal, the preeminent method for non-invasive localization of task-induced brain function in human subjects, reflects a combination of changes in CBV ...
Huisman Sander G - - 2012
The flow structure of strongly turbulent Taylor-Couette flow with Reynolds numbers up to Re_{i}=2×10^{6} of the inner cylinder is experimentally examined with high-speed particle image velocimetry (PIV). The wind Reynolds numbers Re_{w} of the turbulent Taylor-vortex flow is found to scale as Re_{w}∝Ta^{1/2}, exactly as predicted by Grossmann and Lohse ...
Dong Lixin - - 2012
This study explored using a novel diffuse correlation spectroscopy (DCS) flow-oximeter to noninvasively monitor blood flow and oxygenation changes in head and neck tumors during radiation delivery. A fiber-optic probe connected to the DCS flow-oximeter was placed on the surface of the radiologically/clinically involved cervical lymph node. The DCS flow-oximeter ...
Putnam Andrea - - 2012
The characterization of unwinding reactions by RNA helicases often requires the determination of rate constants that are too fast to be measured by traditional, manual gel-based methods. Stopped-flow fluorescence measurements allow access to fast unwinding rate constants. In this chapter, we outline strategies and experimental considerations for the design of ...
Versluis Bas - - 2012
The aim of this work was to develop a MRI method to determine arterial flow reserve in patients with intermittent claudication and to investigate whether this method can discriminate between patients and healthy control subjects. Ten consecutive patients with intermittent claudication and 10 healthy control subjects were included. All subjects ...
Crowley Caitlin - - 2012
Hemoglobin (Hb) concentration is the central diagnostic indicator for anemia, including nutritional anemia. The objective of this study was to compare the Hb values determined by two portable, non-invasive devices across a wide Hb spectrum against formal laboratory measurements, and with each other. Eighty Guatemalan adults (40 highland men, 40 ...
Kulej Mirosław - - 2012
The aim of this paper is to evalute perioperative blood loss associated with total cemented knee joint alloplasty, with special regard to specific factors that may influence this loss. Additionally, the significance of postoperative autotransfusion in these procedures is assessed. The study group consisted of 85 patients (61 females and ...
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