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Shafique Ahmad Abdullah A Department of Anesthesiology, and Center for Translational Research in Neurodegenerative Disease, University of Florida College of Medicine, Gainesville, FL USA. Electronic address: - - 2014
Stroke is a leading cause of death and morbidity worldwide, yet effective treatments are lacking. The association of prostaglandin D2 and its DP1 receptor with vasculature and blood propelled us to examine whether the clinically tested DP1 receptor agonist BW245C had beneficial effects following stroke. To determine if BW245C affects ...
Berthet Carole C Department of Clinical Neurosciences, Neurology Service, Centre Hospitalier Universitaire Vaudois, Lausanne, - - 2014
The treatments for ischemic stroke can only be administered in a narrow time-window. However, the ischemia onset time is unknown in ~30% of stroke patients (wake-up strokes). The objective of this study was to determine whether MR spectra of ischemic brains might allow the precise estimation of cerebral ischemia onset ...
Ward Lucy L Jersey General Hospital in St Helier, - - 2014
I work in an emergency assessment unit, and have worked in several stroke units. Reading the CPD article updated my knowledge of the care of patients who have had a stroke, particularly in relation to blood glucose monitoring and management.
Stokes Ashley M AM Department of Radiology and Radiological Sciences, Vanderbilt University, Nashville TN 37232, USA; Institute of Imaging Science, Vanderbilt University, Nashville TN 37232, - - 2014
The goal of this study was to optimize and validate a combined spin- and gradient-echo (SAGE) sequence for dynamic susceptibility contrast (DSC)-MRI to obtain hemodynamic parameters in a preclinical setting. The SAGE EPI sequence was applied in phantoms and in vivo rat brain (normal, tumor, and stroke tissue). Partial and ...
Terabayashi Nobuo N Department of Orthopaedic Surgery, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, Gifu, 501-1194, Japan, - - 2014
Night pain is a particularly vexing symptom in patients with rotator cuff tear. It disturbs sleep and decreases quality of life, and there is no consensus regarding its etiology. Based on arthroscopic surgical observations of synovitis around the rotator interval or capsule surface in rotator cuff tear, we hypothesized that ...
Mohammed B M BM Coagulation Advancement Laboratory, Department of Pharmacotherapy and Outcomes Science, Virginia Commonwealth University, Richmond, VA, USA; Department of Clinical Pharmacy, Faculty of Pharmacy, Cairo University, 11562, Cairo, - - 2014
The thrombin generation assay (TGA) is an important global coagulation assay; however, it suffers from the lack of pre-analytical standardization. The addition of corn trypsin inhibitor (CTI) to blood collection tubes prior to TGA has been previously advocated to block the contact activation pathway. Emerging data, however, suggest that CTI ...
Yan Ronald R Department of Laboratory Medicine, Dr Everett Chalmers Regional Hospital, Horizon Health Network, Fredericton, New Brunswick, Canada Dalhousie Medical Program in New Brunswick, Saint John, New Brunswick, - - 2014
To investigate the suitability of newly developed Becton Dickinson Vacutainer rapid serum tube (RST) for therapeutic drug monitoring of antibiotics and anticonvulsants. Two pools of citrated whole blood were created by spiking high and low concentrations of gentamicin, vancomycin, phenytoin, lamotrigine and carbamazepine. After recalcification with 15 mmol/L calcium chloride, spiked ...
Kaminker V V Department of Chemistry, University of Alaska Anchorage, Anchorage 99508, Alaska, - - 2014
When a flowing fluid is channeled by chemical or physical precipitation, then tubular structures form. These patterns are common in nature, however, there have been few quantitative studies of their formation. Here, we report measurements of the radius, length, and internal pressure, as functions of time and flow rate, for ...
Hirose Keiko K Department of Otolaryngology, Washington University School of Medicine, 660 South Euclid Avenue, Campus, Box 8115, St. Louis, MO, 63110, USA, - - 2014
The blood vessels that supply the inner ear form a barrier between the blood and the inner ear fluids to control the exchange of solutes, protein, and water. This barrier, called the blood-labyrinth barrier (BLB) is analogous to the blood-brain barrier (BBB), which plays a critical role in limiting the ...
Kim Bo Hyun BH Department of Laboratory Medicine, College of Medicine, Chung-Ang University, Seoul, South - - 2014
An accurate determination of blood ethanol concentrations is important. To minimize ethanol degradation in blood samples, sodium fluoride (NaF) collection tubes have been recommended for use. In this study, we attempted to utilize the Olympus AU5421 chemistry analyzer for ethanol analysis based on the parameters established for the Toshiba 200FR. ...
Ip Hing Lung HL Divison of Neurology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, SAR, - - 2014
Recent advances in ischemic stroke enable a seamless transition of the patient flow from the prehospital setting to definitive reperfusion, without the arbitrary separation of therapeutic phases of ischemia based on time alone. In 2013, the framework to understand and directly address the pathophysiology of cerebral blood flow that determines ...
Peng Z Z Department of Clinical Laboratory, The Children's Hospital Zhejiang University School of Medicine, Hangzhou, - - 2014
The research demonstrated the way to compare performances of five capillary blood collection tubes for capillary blood collections among patients with pediatrics utilizing the Clinical and Laboratory Standards Institute (CLSI) document EP9-A2. A questionnaire survey was distributed to evaluate the accessibility and reliability of capillary blood collection tubes from different ...
Zanella Fabio F Department of Cardiac, Thoracic and Vascular Sciences, Cardiovascular Perfusion Unit, University of Padua, - - 2014
To conceive a method to deliver cold blood cardioplegia in neonates and young infants. The "tube-in-tube" circuit consists of a 3-mm line (bloodline) which is inserted inside a 1/2 -in tube where cold water flows continuously (waterline). This circuit includes a filling volume of 18 mL of static prime and ...
Ku A Sw AS Department of Paediatrics and Adolescent Medicine, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong - - 2014
Falsely elevated serum or plasma potassium level can be the result of mechanical injury to blood cells. We describe pseudohyperkalaemia caused by pneumatic tube transport of blood specimens from a patient with leukaemia. Clinicians should be aware of this possibility when interpreting the clinical significance of hyperkalaemia. In leukaemic patients, ...
Xu Xiangqun - - 2014
ABSTRACT. Our previous work demonstrated that an optical coherence tomography (OCT) technique was able to characterize the whole blood coagulation process. The 1/e light penetration depth (d1/e) derived from the profiles of reflectance versus depth was developed for detecting the whole blood coagulation process in static state. To consider the ...
Nagai Mirei M Department of Anesthesiology, Tokyo Women's Medical University, Tokyo, - - 2014
Thrombogenic reactions under multiple interactions of pharmacological agents, doses, and materials have not been well understood yet. The aim of this study was to investigate the ability to simultaneously compare thrombogenic reactions to different combinations of anticoagulants, doses, and blood-contacting materials, in a single human blood using an in vitro ...
Fobker Manfred - - 2014
Abstract Background: People with hyperglycemia, especially those who are pregnant, depend on accurate blood glucose measurements for correct diagnosis of diabetes and monitoring. Glycolysis after blood draw, however, decreases glucose concentrations in blood that is collected at room temperature in the absence of a stabilizer. Cold temperatures (4°C) inhibit glycolysis; ...
Hashiuchi Tomohisa T Department of Orthopedics, Nishinara Central Hospital, 1-15 Tsurumainishimachi, Nara, 631-0022, Japan, - - 2014
Superior labrum anterior and posterior (SLAP) lesions due to overuse by repeated pitching motion and trauma are often noted and usually. However, shoulder disorders with a chronic course are often accompanied by SLAP lesions. SLAP lesions are frequently observed during arthroscopic surgery of the shoulder joint for rotator cuff tear ...
Lima-Oliveira Gabriel G 1 Laboratory of Clinical Biochemistry, Department of Life and Reproduction Sciences, University of Verona , Verona, Italy - - 2014
Background: The preanalytical phase is considered the most vulnerable phase in biopreservation, biobanking, and laboratory diagnostics. Accurate mixing after blood collection is claimed to be important and recommended by the manufacturers. Objective: To evaluate whether it is really necessary to mix the primary blood tubes immediately after blood collection by ...
Pichler M M Clinical Unit for Herd Health Management for Ruminants, University Clinic for Ruminants, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine Vienna, 1210 Vienna, - - 2014
Metabolic disorders, especially hyperketonemia, are very common in dairy sheep. The whole-blood concentrations of β-hydroxybutyrate (BHBA) and glucose can be determined by commercially available electronic hand-held devices, which are used in human medicine and for the detection of ketosis in dairy cows. The aim of this study was to evaluate ...
Kara Hasan H Hasan Kara, Selcuk University, Faculty of Medicine, Department of Emergency Medicine, Konya, - - 2014
The frequency of hemolysis of blood samples may be increased by transport in a pneumatic tube system. The purpose of this study was to evaluate the effect of pneumatic tube system transport on hemolysis of blood samples. Blood samples were transported from the emergency department to the hospital laboratory manually ...
Wiest Roland R Support Center for Advanced Neuroimaging (SCAN), Institute for Diagnostic and Interventional Neuroradiology, University Hospital Inselspital and University of Bern, Bern, - - 2014
Unilateral ischemic stroke disrupts the well balanced interactions within bilateral cortical networks. Restitution of interhemispheric balance is thought to contribute to post-stroke recovery. Longitudinal measurements of cerebral blood flow (CBF) changes might act as surrogate marker for this process. To quantify longitudinal CBF changes using arterial spin labeling MRI (ASL) ...
Al-Riyami A Z AZ Department of Hematology, Sultan Qaboos University Hospital, Muscat, - - 2013
Effect of the pneumatic tube system (PTS) on sample quality is controversial. Herein we aim at evaluating the impact of sample transportation via the PTS on complete blood count (CBC) results. Duplicate CBC samples from normal donors and anemic patients were sent in parallel to the laboratory for testing through ...
Sladkevicius Povilas P Department of Obstetrics and Gynecology, Skåne University Hospital Malmö, Lund University, Malmö, - - 2013
To assess if B-flow ultrasound (BF) improves visualization of flow of contrast medium in the Fallopian tubes during hystero-salpingo-contrast sonography (HyCoSy) compared to gray scale (GS) ultrasound. This prospective observational study includes160 women referred for HyCoSy as part of infertility work-up between January 2011 and September 2012. In each woman, ...
Lippi Giuseppe G Laboratory of Clinical Chemistry and Hematology, Academic Hospital of Parma, Parma, Italy. Electronic address: - - 2013
Spurious hemolysis is the leading source of nonconformities that can be recorded in diagnostic samples, especially those collected in the emergency department (ED). The aim of this study was to assess whether the shift from regular to low volume blood collection tubes may reduce the rate of hemolysis in a ...
Zhang Qiyang Q Department of Chemistry, Wichita State University, Wichita, Kansas, 67260, - - 2013
Integrated microfluidic systems coupled with electrophoretic separations have broad application in biologic and chemical analysis. Interfaces for the connection of various functional parts play a major role in the performance of a system. Here, we developed a rapid prototyping method to fabricate monolithic poly(dimethylsiloxane) (PDMS) interfaces for flow-gated injection, online ...
Conroy Ellen R - - 2013
Resonance tubes are commonly used in voice therapy. These devices modify supraglottal impedance, potentially decreasing the aerodynamic power necessary for phonation. We modeled phonation with resonance tubes in excised larynges and evaluated the effects of varying tube width, tube length, and flow input on phonation threshold pressure (PTP) and phonation ...
Bowen Raffick A R - - 2013
Several previous studies have described the effects of interfering substances on clinical assay results; however, the effects of exogenous substances, particularly additives from blood collection tubes on quality control (QC) specimens and serum specimens have not been well examined. This study examines the effects of blood-collection tube additives on total ...
Hao Lu L Chinese PLA General Hospital, Beijing 100853, - - 2013
Hyperhomocysteinemia and abnormal blood lipids are independent risk factors for stroke. However, whether both factors exert a synergistic effect in the onset of stroke remains unclear. The present study is a retrospective analysis of 2 089 cases of stroke and 2 089 control cases of simple intervertebral disk protrusion using ...
Sone Michihiko - - 2013
To evaluate vascular activity in ears with otosclerosis by intraoperative measurement of blood flow using laser Doppler flowmetry and to compare the data with densitometry on computed tomography (CT). Retrospective case series. University hospital. Thirty-nine ears from 33 patients who underwent surgery for otosclerosis. The subjects were divided into fenestral ...
Kumagai Youichi - - 2013
Construction of a gastric tube that is well perfused with blood during esophagectomy is the most important factor in avoiding anastomotic leakage. We clarified the hemodynamics of the reconstructed gastric tube with indocyanine green (ICG) fluorescence. In 20 patients undergoing gastric tube reconstruction during esophagectomy, we evaluated blood flow in ...
Gaur Rajiv L RL Department of Pathology, Stanford University School of Medicine, Stanford, California, - - 2013
Gamma interferon (IFN-γ) release assays (IGRAs) are functional assays used serially to measure the efficacy of novel tuberculosis (TB) vaccines and to screen health care workers for latent tuberculosis infection (LTBI). However, studies have shown nonreproducible IGRA results. In this study, we investigated the effects of blood volume (0.8, 1.0, ...
Benoit Julien - - 2013
We report the discovery of three isolated primate petrosal fragments from the fossiliferous locality of Chambi (Tunisia), a primate-bearing locality dating from the late early to the early middle Eocene. These fossils display a suite of anatomical characteristics otherwise found only in strepsirhines, and as such might be attributed either ...
Hellberg Victoria - - 2013
Objective: Cisplatin produces toxic lesions to outer hair cells in the cochlear base but not in the apex. The objective of this study was to compare the pharmacokinetic profile of cisplatin in scala tympani perilymph in the cochlear base and apex respectively. Study Design: In vivo animal study. Methods: Forty-seven ...
Zhong Rui - - 2013
This paper reports the results of an in vitro investigation into the blood response of medical grade poly (vinyl chloride) (PVC), and two types of plasticized PVC in tubing or sheet form, with di-(2-ethylhexyl)phthalate (DEHP) and di(isononyl) cyclohexane-1,2-dicarboxylate (HEXAMOLL(®) DINCH) as plasticizer, were selected for assessment of complement activation, coagulation ...
Rohani Mina - - 2013
A self-driven flow was observed in Nafion and other hydrophilic tubes immersed in water. The intratubular flow was generated when water came in contact with the tube's hydrophilic surfaces. Flow characteristics were studied in tubes of varying size, exposed to light of different intensities and wavelengths. The results lead to ...
Heiligers-Duckers Connie - - 2013
OBJECTIVES: In-vitro hemolysis is a great challenge to emergency departments where blood is drawn from intravenous catheters (IVC). Although high quality samples can be obtained by straight needle venipuncture, IVC are preferred for various reasons. The aim of this study was to identify blood collection practices that reduce hemolysis while ...
Grayson Samuel - - 2013
Abstract Ear reconstruction with autologous rib cartilage is performed in stages. Restitution of blood flow between the separate stages is crucial to obtain a good result. Laser Doppler perfusion imaging (LDPI) and local temperature were measured in reconstructed and normal ears in response to indirect heating. Ten persons who had ...
Jørgensen Pelle - - 2013
Using simulation as an approach to display and improve internal logistics at hospitals has great potential. This study shows how a simulation model displaying the morning blood-taking round at a Danish public hospital can be developed and utilized with the aim of improving the logistics. The focus of the simulation ...
Lin Ting-Yu - - 2013
In this paper, the scale effects are specifically addressed by conducting experiments with air flow in different microtubes. Three stainless steel tubes of 962, 308, and 83 μm inner diameter (ID) are investigated for friction factor, and the first two are investigated for heat transfer. Viscous heating effects are studied in ...
Eckmann David M DM Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA 19104, USA. - - 2013
This study was undertaken to evaluate the effects of thin film hyaluronic acid and dextran surface coatings to blunt cellular activation in a laboratory model of extracorporeal blood circulation. The inner lumen surface of polyurethane (PU) and poly(vinyl) chloride (PVC) tubing was grafted with hyaluronic acid and dextran. Surfaces were ...
Lippi Giuseppe - - 2013
OBJECTIVES: Samples drawn through intravenous catheters are frequently hemolyzed. We planned a prospective, randomized study to establish whether hemolysis in samples drawn from intravenous catheters may be reduced using the S-Monovette® collected by manual aspiration as compared with standard vacuum tubes. Design and Methods We studied 52 consecutive patients admitted ...
Waters Jon - - 2013
Laboratory tests can be done on the cellular or fluid portions of the blood. The use of different blood collection tubes determines the portion of the blood that can be analyzed (whole blood, plasma or serum). Laboratories involved in studying the genetic basis of human disorders rely on anticoagulated whole ...
Fujii Chieko - - 2013
The purpose of this study was to assess specific vacuum-venipuncture skills and the influence of the time involved in skin puncture and blood collection. Thirty subjects undergoing venipuncture in which video analysis was possible were included. These procedures were carried out by four nurses and recorded with a digital camera. ...
Lippi Giuseppe G U.O. di Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero-Universitaria di Parma, Italy. - - 2013
In vitro hemolysis can be induced by several biological and technical sources, and may be worsened by forced aspiration of blood in vacuum tubes. This study was aimed to compare the probability of hemolysis by drawing blood with a commercial evacuated blood collection tube, and S-Monovette used either in the ...
Lippi Giuseppe G Clinical Chemistry Laboratory, Academic Hospital of Parma, Parma, Italy. - - 2013
Blood collection through intravenous lines frequently causes spurious hemolysis. Due to specific structure, the tube holder Holdex (Greiner Bio-One GmbH, Kremsmuenster, Austria) is supposed to prevent erythrocyte injury in samples collected from catheters, so that we planned a specific study to support this hypothesis. Blood was collected from emergency department ...
Lima-Oliveira Gabriel G Laboratory of Clinical Biochemistry, Department of Life and Reproduction Sciences, University of Verona, Verona, Italy. - - 2013
Procedures involving phlebotomy are critical for obtaining diagnostic blood specimens and represent a well known and recognized problem, probably among the most important issues in laboratory medicine. The aim of this report is to show spurious hyperkalemia and hypocalcemia due to inadequate phlebotomy procedure. The diagnostic blood specimens were collected ...
Yavaş Soner S Türkiye Yüksek İhtisas Education and Research Hospital, Cardiovascular Surgery Clinic, Ankara, - - 2012
Coagulation tests are influenced by pre-analytic conditions such as blood collection systems. Change of glass collection tubes with plastic ones will cause alteration of the test results. The aim of this study was to compare three plastic blood collection tubes with a standard glass blood collection tube and each plastic ...
Pazzagli M - - 2012
The diagnostic use of in vitro molecular assays can be limited by the lack of guidelines for collection, handling, stabilization and storage of patient specimens. One of the major goals of the EC funded project SPIDIA (www.spidia.eu) is to develop evidence-based quality guidelines for the pre-analytical phase of blood samples ...
Gros Nataša - - 2012
Abstract Background: An inappropriate anticoagulant concentration in a blood sample can cause cell shrinkage and affect the haematocrit and mean corpuscular volume (MCV). In evacuated blood-collection tubes there are two parameters affecting the quality of the product: the anticoagulant amount introduced into the tube during its production and the internal ...
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