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Suarez Jose I JI Division of Vascular Neurology and Neurocritical Care, Baylor College of Medicine, Baylor St Luke's Medical Center, 6501 Fannin ST, NB:302, Houston, TX, 77030, USA, - - 2015
The neuroprotective effects of human albumin have been studied in animal models of stroke and in humans with various intracranial disorders. We investigated the effect of 25 % human albumin (ALB) on mean cerebral blood flow velocities (MCBFV), delayed cerebral ischemia (DCI), and cerebral infarction. We studied patients from the ...
Adad Sheila Jorge SJ Discipline of Special Pathology, Universidade Federal do Triangulo Mineiro, Uberaba, MG, - - 2014
This study aimed to determine the existence of blood vessels within ganglia of the myenteric plexus of the human esophagus and colon. At necropsy, 15 stillborns, newborns and children up to two years of age, with no gastrointestinal disorders, were examined. Rings of the esophagus and colon were analyzed and ...
Waleckx Etienne - - 2014
To evaluate human risk for Chagas disease, we molecularly identified blood meal sources and prevalence of Trypanosoma cruzi infection among 49 Triatoma sanguisuga kissing bugs in Louisiana, USA. Humans accounted for the second most frequent blood source. Of the bugs that fed on humans, ≈40% were infected with T. cruzi, ...
Asadi Amran K AK University of California, San - - 2014
Hypoxic pulmonary vasoconstriction (HPV) is thought to actively regulate ventilation-perfusion (V̇A/Q) matching, reducing perfusion in regions of alveolar hypoxia. We assessed the extent of HPV in the healthy human lung using inhaled nitric oxide (iNO) under inspired oxygen fractions (FIO2) of 0.125, 0.21 and 0.30 (a hyperoxic stimulus designed to ...
Holm Karen Marie Dollerup KM Section of Forensic Chemistry, Department of Forensic Medicine, Faculty of Health Sciences, University of Copenhagen, Frederik V's Vej 11, DK-2100, Copenhagen, - - 2014
Knowledge concerning the distribution of methadone in postmortem human tissue and the effect of postmortem redistribution on methadone is today limited making the choice of a suitable substitute for femoral blood difficult when this is not available. Cardiac blood, femoral blood, muscle, and brain tissue concentrations of the enantiomers of ...
Martusevich A K AK Nizhny Novgorod Research Institute of Traumatology and Orthopedics, Nizhny Novgorod, Russia, - - 2014
We studied the influence of NO-containing gas phase on some parameters of energy metabolism in human erythrocytes. Whole blood samples were aerated with gas flows from the Plazon instrument (NO concentrations 800 and 80 ppm) and from the experimental generator (75 ppm). Activity of lactate dehydrogenase in direct and reverse ...
Vieira-Damiani Gislaine G Division of Dermatology, Department of Medicine, State University of Campinas (UNICAMP) Medical School, Campinas, SP, - - 2014
Human exposure to Bartonella clarridgeiae has only been reported on the basis of antibody detection. We report for the first time an asymptomatic human blood donor infected with B. clarridgeiae, as documented by enrichment blood culture, PCR and DNA sequencing.
Kolter Marise M Institute of Pharmacy and Molecular Biotechnology, University of Heidelberg, Heidelberg, Germany. Electronic address: - - 2014
Therapy of diseases of the central nervous system is a major challenge since drugs have to overcome the blood-brain barrier (BBB). A powerful strategy to enhance cerebral drug concentration is administration of drug-loaded poly(n-butylcyano-acrylate) (PBCA) nanoparticles coated with polysorbate 80 (PS80). This study evaluates the toxicity of PBCA-nanoparticles at the ...
Cui Jiwei J Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria, 3010, - - 2014
On page 7295, F. Caruso and co-workers report a mesoporous silica templating method for preparing super-soft PEG particles. The elasticity of the particles can be tuned to mimic the deformability behaviour of human red blood cells in a microfluidic blood-capillary model. These particles provide a new platform for investigating bio-nano ...
Zigdon-Giladi Hadar H Department of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus, Haifa, Israel; Research Institute for Bone Repair, Rambam Health Care Campus, Haifa, Israel; The Rappaport Family Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, - - 2014
Endothelial progenitor cells (EPC) participate in angiogenesis and osteogenesis therefore have the potential to enhance extra-cortical bone formation. To enhance extra-cortical bone formation following local transplantation of human peripheral blood derived EPC (hEPC) in a guided bone regeneration (GBR) nude rat calvaria model. hEPC were isolated from peripheral blood of ...
Forbes Shari L SL Centre for Forensic Science, University of Technology Sydney, PO Box 123, Broadway, NSW, 2007, Australia, - - 2014
Cadaver-detection dogs are used by the police to locate missing persons, victims of homicide, and human remains following mass disasters. Training is conducted using a variety of training aids including blood which can be hours, weeks or months old and stored under variable conditions. The aim of this study was ...
Grisendi Giulia G Division of Oncology, Department of Medical and Surgical Sciences for Children & Adults, University-Hospital of Modena and Reggio Emilia, Modena, - - 2014
During storage, red blood cells (RBC) undergo chemical and biochemical changes referred to as "storage lesions". These events determine the loss of RBC integrity, resulting in lysis and release of microparticles. There is growing evidence of the clinical importance of microparticles and their role in blood transfusion-related side effects and ...
Untenberger Markus M Biomedizinische NMR Forschungs GmbH am Max-Planck Institut für biophysikalische Chemie, Göttingen, - - 2014
To develop and evaluate a practical phase unwrapping method for real-time phase-contrast flow MRI using temporal and spatial continuity. Real-time phase-contrast MRI of through-plane flow was performed using highly undersampled radial FLASH with phase-sensitive reconstructions by regularized nonlinear inversion. Experiments involved flow in a phantom and the human aorta (10 ...
Endo Shunsuke S Department of General Thoracic Surgery, Jichi Medical University, Tochigi, - - 2014
To elucidate the role of fluid mechanical factors in the localized genesis and development of atherosclerotic lesions in man.METHODS: Flow patterns and preferred sites of atherosclerotic lesions in the human aortic arch were studied in detail using isolated transparent aortic trees prepared from humans postmortem and by means of flow ...
Sohrabi Salman - - 2014
To quantify the transport and adhesion of drug particles in a complex vascular environment, computational fluid particle dynamics (CFPD) simulations of blood flow and drug particulate were conducted in three different geometries representing the human lung vasculature: artificial, original and over-smoothed geometry. The flow boundary conditions used include both steady-state ...
Gürtler Ricardo E RE Laboratory of Eco-Epidemiology, Department of Ecology, Genetics and Evolution, Universidad de Buenos Aires-IEGEBA (CONICET-UBA), Buenos Aires, - - 2014
Triatoma infestans -the principal vector of the infection that causes Chagas disease- defies elimination efforts in the Gran Chaco region. This study identifies the types of human-made or -used structures that are key sources of these bugs in the initial stages of house reinfestation after an insecticide spraying campaign. We ...
Nowak Sascha S Institute of Inorganic and Analytical Chemistry, University of Münster, Corrensstrasse 30, 48149, Münster, Germany, - - 2014
Low gas flow ICP-OES with a total argon consumption below 0.7 L/min is introduced for the analysis of trace elements in blood samples to investigate the influence of samples containing an organic solvent in a demanding matrix on the performance of this plasma for the first time. Therefore, gadolinium was determined ...
Yonan K A KA Department of Biology and Chemistry and Department of Computer of Mathematical Sciences, New Mexico Highlands University, Las Vegas, New - - 2014
Non-invasive transcranial Doppler (TCD) is widely used for blood velocity (BV, cm/sec) measurements in the human middle cerebral artery (MCA). MCABV measurements are accepted as linear with MCA blood flow (MCABF). Magnetic resonance angiography (MRA) provides measurements of MCA lumen diameters that can be combined with TCD MCABV to calculate ...
Cui Jiwei J Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria, 3010, - - 2014
Super-soft PEG hydrogel particles with tunable elasticity are prepared via a mesoporous silica templating method. The deformability behavior of these particles, in a microfluidic blood capillary model, can be tailored to be similar to that of human red blood cells. These results provide a new platform for the design and ...
Manjappa Bhagyalakshmi B aDepartment of Studies and Research in Biochemistry and Centre for Bioscience and Innovation, Tumkur University, Tumkur, Karnataka bDepartments of Studies in Biochemistry, University of Mysore, Manasagangothry, Mysore, India cDepartments of Studies in Biochemistry, Kuvempu University, Shankaraghatta, Shimoga, Karnataka, India dDepartments of Sericulture, Yuvaraja's College, University of Mysore, Mysore, - - 2014
The current study explores the anticoagulant and fibrin clot-hydrolyzing properties of Momordica charantia seed extract (MCSE). MCSE hydrolyzed casein with the specific activity of 0.780 units/mg per min. Interestingly, it enhanced the clot formation process of citrated human plasma from control 146 to 432 s. In addition, the intravenous injection of MCSE ...
Riezzo Irene I Department of Forensic Pathology, University of Foggia, Ospedale C. D'Avanzo, Viale degli Aviatori 1, 71100 Foggia, FG, - - 2014
Dogs are commonly used to detect explosives, narcotics, and other illegal materials. In the forensic setting, cadaver dogs are trained to detect and locate concealed human remains or fluids due to the high sensitivity and selectivity of the canine olfactory system and the relative ease with which dogs can be ...
Stevens Lori L Department of Biology, College of Arts and Sciences, University of Vermont, Burlington, Vermont, United States of - - 2014
Triatoma dimidiata, currently the major Central American vector of Trypanosoma cruzi, the parasite that causes Chagas disease, inhabits caves throughout the region. This research investigates the possibility that cave dwelling T. dimidiata might transmit the parasite to humans and links the blood meal sources of cave vectors to cultural practices ...
Shalaby Sherif S Department of Vascular Surgery, Yale University School of Medicine, New Haven, - - 2014
Extracellular signal-regulated kinase 5 (ERK5) has been reported to regulate endothelial cell integrity and protect from vascular dysfunction under continuous laminar flow. However, the effect of flow on ERK5 levels has not been determined. Confluent human umbilical vein endothelial cells (HUVECs) were seeded on fibronectin coated glass slides and serum ...
Killeen Gerry F - - 2014
Eliminating malaria requires vector control interventions that dramatically reduce adult mosquito population densities and survival rates. Indoor applications of insecticidal nets and sprays are effective against an important minority of mosquito species that rely heavily upon human blood and habitations for survival. However, complementary approaches are needed to tackle a ...
Acharya Saraswati S Department of Natural Sciences (Mathematics), School of Science, Kathmandu University, Nepal. Electronic address: - - 2014
Skin temperature is a common physiological parameter that reflects thermal responses. Blood perfusion is an important part of the physiological processes that the human body undergoes in order to maintain homeostasis. This study focuses on the effect of perfusion on the temperature distribution in human males and females body in ...
Babayemi Joshua J Department of Chemistry, Faculty of Science, University of Ibadan, Ibadan, - - 2014
This study investigated the material/substance flow of polybrominated diphenyl ethers listed in the Stockholm Convention (SC) as persistent organic pollutant (POP-PBDEs) in the most relevant plastic fractions in Nigeria. Considering the prohibition of production and the use of POP-PBDEs and knowing that these pollutants are still contained in electrical and ...
Kim Minyoung Kevin MK Department of Chemistry, Princeton University, Princeton, NJ - - 2014
Biofilms are surface-associated conglomerates of bacteria that are highly resistant to antibiotics. These bacterial communities can cause chronic infections in humans by colonizing, for example, medical implants, heart valves, or lungs. Staphylococcus aureus, a notorious human pathogen, causes some of the most common biofilm-related infections. Despite the clinical importance of ...
Park Hyun-Seok HS Busan-Ulsan Regional Cardio-Cerebral Vascular Center, Dong-A University Hospital, Busan, Republic of - - 2014
In this study, we evaluated the relationship between the rCBV (regional cerebral blood flow volume) ratio on perfusion-weighted imaging (PWI) and the extent of collateral flow on conventional angiography. We recruited 98 patients with AIS (within 24h after ischemic events). All the patients were evaluated by MRI, including PWI and ...
Falcone Franco H FH Division of Molecular and Cellular Science, The School of Pharmacy, The University of Nottingham, Boots Science Building, Science Road, Nottingham, NG7 2RD, UK, - - 2014
The purification of basophils from peripheral blood has represented a formidable challenge for researchers since they were discovered by Paul Ehrlich in 1879. From the first published attempts in the late 1960s, it took half a century to develop robust protocols able to provide sufficient numbers of pure, functionally unimpaired ...
Devin Jessica K JK Department of Medicine, Vanderbilt University Medical Center, Nashville, TN (J.K.D., - - 2014
Dipeptidyl-peptidase 4 (DPP4) inhibitors improve glycemic control in patients with diabetes mellitus by preventing the degradation of glucagon-like peptide-1 (GLP-1). GLP-1 causes vasodilation in animal models but also increases sympathetic activity; the effect of GLP-1 in the human vasculature and how it is altered by DPP4 inhibition is not known. ...
Reverón Rafael Romero - - 2014
Herophilus (c335 - c280 B.C.) was the founder of the school of anatomy of Alexandria, and was among the first physicians to conduct anatomical dissections in public. He made extraordinary anatomical discoveries and developed standards for measuring the flow of blood from the heart through the arteries. Erasistratus (c310- c250 ...
Toh Rou Jun RJ 1] Division of Chemistry &Biological Chemistry School of Physical and Mathematical Sciences, Nanyang Technological University, 637371, Singapore [2] BioSystems &Micromechanics IRG (BioSyM), Singapore-MIT Alliance for Research and Technology (SMART) Centre, 1 CREATE Way, #04-13/14 Enterprise Wing, 138602, - - 2014
The electrochemical behavior of iron ion in haemoglobin provides insight to the chemical activity in the red blood cell which is important in the field of hematology. Herein, the detection of haemoglobin in human red blood cells on glassy carbon electrode (GC) was demonstrated. Red blood cells or raw blood ...
Bernardoni Juliana L JL Laboratório de Imunopatologia, Instituto Butantan, São Paulo, SP, - - 2014
Snake venom metalloproteinases (SVMPs) are major components in most viperid venoms that induce disturbances in the hemostatic system and tissues of animals envenomated by snakes. These disturbances are involved in human pathology of snake bites and appear to be essential for the capture and digestion of snake's prey and avoidance ...
Dyson Rebecca M RM Mothers and Babies Research Centre, Hunter Medical Research Institute, Newcastle, NSW, Australia (R.M.D., H.K.P., J.L.L., I.R.W.) Discipline of Paediatrics and Child Health, School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia (R.M.D., J.L.L., I.R.W.) Graduate School of Medicine and Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW, Australia (R.M.D., - - 2014
Dysfunction of the transition from fetal to neonatal circulatory systems may be a major contributor to poor outcome following preterm birth. Evidence exists in the human for both a period of low flow between 5 and 11 h and a later period of increased flow, suggesting a hypoperfusion-reperfusion cycle over ...
Karabinus David S DS Genetics & IVF Institute, 3015 Williams Dr, Fairfax, VA 22031, USA. - - 2014
Flow cytometric sorting can be used to separate sperm based on sex chromosome content. Differential fluorescence emitted by stained X- vs. Y-chromosome-bearing sperm enables sorting and collection of samples enriched in either X- or Y-bearing sperm for use to influence the likelihood that the offspring will be a particular sex. ...
Nordling Sofia S Department of Immunology, Genetics and Pathology, Uppsala - - 2014
The majority of all known diseases are accompanied by disorders of the cardiovascular system. Studies into the complexity of the interacting pathways activated during cardiovascular pathologies are, however, limited by the lack of robust and physiologically relevant methods. In order to model pathological vascular events we have developed an in ...
Mücke Thomas - - 2013
The end-to-side anastomosis is frequently used in microvascular free flap transfer, but detailed rheological analyses are not available. The purpose of this study was to introduce a new modified end-to-side (Opened End-to-Side, OES-) technique and compare the resulting flow pattern to a conventional technique. The new technique was based on ...
Brut V - - 2013
BACKGROUND: Canine atopic dermatitis can be a result of exposure to aeroallergens or trophallergens. Hemodynamic alterations occur in dogs with food hypersensitivity. HYPOTHESIS/OBJECTIVES: To evaluate if hemodynamic alterations occur in dogs with NFICAD with lowered resistance to diastolic flow at fasting, after feeding, or both. ANIMALS: Ten healthy dogs and ...
Knutsson Linda - - 2013
PURPOSE: To evaluate whether a non-linear blood ΔR(2)*-versus-concentration relationship improves quantitative cerebral blood flow (CBF) estimates obtained by dynamic susceptibility contrast (DSC) MRI in a comparison with Xe-133 SPECT CBF in healthy volunteers. MATERIAL AND METHODS: Linear as well as non-linear relationships between ΔR(2)* and contrast agent concentration in blood ...
Pugliesi G - - 2012
The beginning of functional luteolysis in cattle ranges from Days 16-19 (Day 0=ovulation). During functional luteolysis, luteal size and blood flow decrease in heifers. The wide range of beginning of luteolysis and the low sensitivity of quick progesterone (P4) assays preclude targeting an individual for a specific period of luteolysis. ...
Liotta Janice L - - 2012
Abstract An examination was made of Giemsa-stained microfilariae in thin blood films from dogs naturally or experimentally infected with Dirofilaria immitis or Dirofilaria repens. The blood was from 9 dogs infected with D. immitis and 9 dogs infected with D. repens. Measurements (total length, length of cephalic space, anterior end ...
Jaspers Karolien - - 2012
To validate a novel semi-automatic segmentation algorithm for MR-derived volume and function measurements by comparing it with the standard method of manual contour tracing. The new algorithms excludes papillary muscles and trabeculae from the blood pool, while the manual approach includes these objects in the blood pool. An epicardial contour ...
Rojo Naiara - - 2012
The bacteriostatic properties of carbon disulphide (CS(2)) hamper its biodegradation in conventional biofilters. The response of four biofilters operating in downflow mode and reverse-flow mode was compared in a laboratory-scale plant treating CS(2) under sudden short-term changes in operating conditions. A process shutdown for 24 h, an inlet concentration increase and ...
Khiabani Reza H - - 2012
Total cavopulmonary connection is the result of a series of palliative surgical repairs performed on patients with single ventricle heart defects. The resulting anatomy has complex and unsteady hemodynamics characterized by flow mixing and flow separation. Although varying degrees of flow pulsatility have been observed in vivo, non-pulsatile (time-averaged) boundary ...
Wang Xiaohua - - 2012
Cell salvage devices are routinely used to process red blood cells (RBCs) shed during cardiac surgery. The purpose of this study was to evaluate three commercially available cell saver (CS) devices in terms of erythrocyte function and the quality of washed RBCs during cardiopulmonary bypass (CPB). Thirty patients undergoing CPB ...
Håkansson Andreas - - 2012
Direct determination of hydrodynamic radius from retention time is an advantage of the field-flow fractionation techniques. However, this is not always completely straight forward since non-idealities exist and assumptions have been made in deriving the retention equations. In this study we investigate the effect on accuracy from two factors: (1) ...
Zheng Wenfu - - 2012
This microfluidic flow-stretch chip integrates fluid shear stress (FSS) and cyclic stretch (CS), two major mechanical stimulations in cardiovascular systems, for cultured cells. The model chip can deliver FSS and CS simultaneously or independently to vascular cells to mimic the haemodynamic microenvironment of blood vessels in vivo. By imposing FSS-only, ...
Sparrow Rosemary L RL Research and Development, Australian Red Cross Blood Service, Melbourne, Victoria, Australia. - - 2012
Microparticles (MPs) are shed from normal blood cells and may contribute to the coagulation potential of plasma. Transfusion of fresh frozen plasma (FFP) is used to correct coagulopathies and blood loss in trauma or major surgery. The role of MPs in FFP clinical efficacy is unknown. Regulations that govern the ...
Watanabe Mayumi - - 2012
Mycoplasma arginini, an organism usually recovered from mammals, was isolated from the blood of a febrile patient with advanced non-Hodgkin lymphoma. The patient's condition improved without administration of antimycoplasmal drugs. Simulation of blood culture showed that automated blood culture instruments may fail to detect the organism.
van de Hoef Tim P - - 2012
The assessment of functional coronary lesion severity using intracoronary physiological parameters such as coronary flow velocity reserve and the more widely used fractional flow reserve relies critically on the establishment of maximal hyperemia. We evaluated the diagnostic accuracy of the stenosis resistance index during nonhyperemic conditions, baseline stenosis resistance index, ...
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