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Keklik Muzaffer M Department of Hematology, Faculty of Medicine, Erciyes University, Kayseri, - - 2014
Blood component donations by apheresis have become more common in modern blood transfusion practices. We compared three apheresis instruments (Fenwal Amicus, Fresenius COM.TEC, and Trima Accel) with regard to platelet (PLT) yield, collection efficiency (CE), and collection rate (CR). The single-needle or double-needle plateletpheresis procedures of the three instruments were ...
Murray Katie N KN From the Faculty of Life Sciences (K.N.M., S.M.A.) and Centre for Imaging Science (L.M.P., S.R.W.), University of Manchester, Manchester, United Kingdom; Sainte-Justine Hospital Research Centre, University of Montreal, Canada (S.G.); Glasgow Experimental MRI Centre, The University of Glasgow, Glasgow, United Kingdom (W.M.H.); and University of Manchester, Manchester Academic Health Sciences Centre, United Kingdom - - 2014
Systemic inflammation contributes to diverse acute and chronic brain pathologies, and extensive evidence implicates inflammation in stroke susceptibility and poor outcome. Here we investigate whether systemic inflammation alters cerebral blood flow during reperfusion after experimental cerebral ischemia. Serial diffusion and perfusion-weighted MRI was performed after reperfusion in Wistar rats given ...
Emad Dehkordi S S Department of Land and Water Resources Engineering, Royal Institute of Technology (KTH), 100 44 Stockholm, - - 2014
The effect of array configuration, that is, number, layout, and spacing, on the performance of multiple borehole heat exchangers (BHEs) is generally known under the assumption of fully conductive transport. The effect of groundwater flow on BHE performance is also well established, but most commonly for single BHEs. In multiple-BHE ...
Taccone Fabio Silvio FS Department of Intensive Care, Erasmus Hospital, Université Libre de Bruxelles (ULB), Route de Lennik, 808, 1070, Brussels, Belgium, - - 2014
Hemodynamic monitoring is widely used in critical care; however, the impact of such intervention in patients with acute brain injury (ABI) remains unclear. Using PubMed, a systematic review was performed (1966-August 2013), and 118 studies were included. Data were extracted using the PICO approach. The evidence was classified, and recommendations ...
Kato Takaumi T Graduate School of Biomedical Engineering, Tohoku University, Sendai, 980-8579, - - 2014
Prevention and early detection of atherosclerosis are critical for protection against subsequent circulatory disease. In this study, an automated two-dimensional ultrasonic-measurement-integrated (2D-UMI) blood flow analysis system for clinical diagnosis was developed, and the feasibility of the system for hemodynamic analysis in a carotid artery was revealed. The system automatically generated ...
Kishimoto Satoru S Department of Artificial Organs, National Cerebral and Cardiovascular Center Research Institute, 5-7-1 Fujishiro-dai Suita, Osaka, 565-8565, Japan, - - 2014
We developed a novel controller for a continuous-flow left ventricular assist device (EVAHEART) that can change the pump's rotational speed (RS) in synchronization with a patient's myocardial electrocardiogram (ECG) with the aim of facilitating cardiac recovery. We previously presented various applications of this system in animal models, but there remained ...
Hamlin Shannan K SK Nursing Research and Evidence-Based Practice, Houston Methodist Hospital, MGJ 11-017, Houston, TX 77030, USA. Electronic address: - - 2014
The cardiovascular system (macrocirculation) circulates blood throughout the body, but the microcirculation is responsible for modifying tissue perfusion and adapting it to metabolic demand. Hemodynamic assessment and monitoring of the critically ill patient is typically focused on global measures of oxygen transport and utilization, which do not evaluate the status ...
Liu Xiao X Key Laboratory for Biomechanics and Mechanobiology of the Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, - - 2014
Helical flow in the human aorta is possibly a typical example of 'form follows function' in the vascular system. The helical blood flow may provide guaranties for the inner surface of the ascending aortic wall to get smooth and even washing by the blood so that atherosclerotic plaques can hardly ...
Nakada Tsutomu T Tsutomu Nakada, Center for Integrated Human Brain Science, Brain Research Institute, University of Niigata, 1-757 Asahimachi, Niigata, 951-8585, Japan, - - 2014
Recent studies have strongly indicated that the classic circulation model of cerebrospinal fluid (CSF) is no longer valid. The production of CSF is not only dependent on the choroid plexus but also on water flux in the peri-capillary (Virchow Robin) space. Historically, CSF flow through the Virchow Robin space is ...
Qiao Heyuan - - 2014
In the cryopreservation of blood, removing cryoprotectants from the cryopreserved blood safely and effectively is always being focused on. In our previous work, a dilution-filtration system was proposed to achieve the efficient clearance of cryoprotectants from the cryopreserved blood. In this study, a theoretical method is presented to optimize the ...
Arfvidsson Berndt - - 2014
Abstract Background: Our aim was to test the hypothesis that metabolic and inflammatory responses of the brain perioperatively during carotid endarterectomy (CEA) might affect blood brain barrier (BBB) integrity. Methods: Twenty patients with >70% stenosis of internal carotid artery (ICA) were prospectively included. Surgery was performed under general anaesthesia. Blood ...
Vahidnia Ali A Molecular Diagnostic Laboratory, Atal-Medial Medical Diagnostic Center, Jan Tooropstraat 138, 1061 AD, Amsterdam, the Netherlands. Electronic address: - - 2014
The purpose of this study is to introduce a high-throughput system, Aurora FLOW, for the simultaneous detection of 3 clinically relevant pathogens of sexually transmitted infections. Comparative evaluation with other systems revealed an overall concordance of 97.9% for Chlamydia trachomatis and comparable performance for Neisseria gonorrhoeae and Trichomonas vaginalis.
Bilgili Mustafa Gökhan MG Department of Orthopedics and Traumatology, Bakırköy Dr. Sadi Konuk Research and Training Hospital, İstanbul, - - 2014
Blood loss and replacement is still a controversial issue in major orthopaedic surgery. Allogenic blood transfusion may cause legal problems and concerns regarding the transmission of transfusion-related diseases. Cellsaver Systems (CSS) were developed as an alternative to allogenic transfusion but CSS transfusion may cause coagulation, infection and haemodynamic instability. Our ...
Aalaei Shokoufeh S Student Research Committee, Department of Medical Informatics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, - - 2014
Storage and transportation of red blood cells (RBCs) outside the standard temperature range as defined by guidelines can lead to hemolysis. One of the main factors believed to cause hemolysis is temperature.Infusion of the corrupted RBCs leads to haemolytic reactions which are severe and life-threatening. We developed a temperature monitoring ...
Slee Joshua B JB Division of Cardiology, Department of Pediatrics, The Children's Hospital of Philadelphia; University of Pennsylvania Perelman School of - - 2014
The foreign body reaction occurs when a synthetic surface is introduced to the body. It is characterized by adsorption of blood proteins and the subsequent attachment and activation of platelets, monocyte/macrophage adhesion, and inflammatory cell signaling events, leading to post-procedural complications. The Chandler Loop Apparatus is an experimental system that ...
He Wenbo W School of Energy and Power Engineering, Xi'an Jiaotong University, Xi'an 710049, Shaanxi, - - 2014
Generating an artificial blood flow in a circle system is an important step in hemodynamic research; thus, the influence of circle system components on the pulsatile flow wave forms should be investigated. In this study, a circle system was built, in which two solenoid valves were controlled by a timer ...
Zhang Yang Y Department of Fluid Machinery and Engineering, Xi'an Jiaotong University, Xianning Western Road 28, Xi'an 710049, - - 2014
A novel Particle Tracking Velocimetry (PTV) algorithm based on Voronoi Diagram (VD) is proposed and briefed as VD-PTV. The robustness of VD-PTV for pulsatile flow is verified through a test that includes a widely used artificial flow and a classic reference algorithm. The proposed algorithm is then applied to visualize ...
Louis Elan D - - 2013
Parkinson's disease (PD) is a late-life neurodegenerative disease. Genetic and environmental factors play an etiological role. Harmane (1-methyl-9H-pyrido[3,4-b]indole) is a potent tremor-producing neurotoxin that shows structural resemblance to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). In 2002 and 2007, we demonstrated elevated blood harmane concentrations [HA] in essential tremor (ET) cases. We now assessed whether ...
Bolat Ahmet A Department of Pediatrics, Gulhane Military Medical Academy and Medical Faculty, Ankara, - - 2013
The aim of this study was to investigate the changes in the peripheral blood of newborns of hypertensive mothers. The umbilical cord blood from newborns of 31 hypertensive mothers and 32 healthy mothers were examined. In all subjects, complete blood count, peripheral blood smear, reticulocyte count, vitamin B12, folate, ferritin ...
Fujishima Hiroshi - - 2013
Eosinophils appear to be key cells in the pathogenesis of conjunctival inflammation in atopic keratoconjunctivitis (AKC). Chemoattractant receptor homologous molecule expressed on TH2 cells (CRTH2) mediates prostaglandin D2 (PGD2)-dependent migration of eosinophils. However, it is unclear whether CRTH2/PGD2-dependent eosinophil migration is upregulated in allergic diseases. To compare the chemotactic responses ...
Pitini Vincenzo - - 2013
A previously healthy 14-years old male was admitted to hospital with a 10 day history of remittent fever. Physiscal examination showed moderate hepatosplenomegaly and generalized lymphadenopathy. Laboratory tests revealed AST 490 IU/L, ALT 596 IU/L, and pancytopenia (haemoglobin 101 g/l, WBC 2.1 x10(9) /l, platelets 86x10(9) /l). Morphologic examination of ...
Asenso-Mensah Kwame - - 2013
BACKGROUND: In sub-Saharan Africa (SSA) confirmed viral marker prevalence between family donors (FDs) and first-time volunteer nonremunerated donors (VNRDs) is similar. In a blood service collecting 10 units/1000 inhabitants, a questionnaire examined FD donation conditions and willingness of becoming repeat VNRDs. STUDY DESIGN AND METHODS: Four areas were explored: circumstances ...
Kwak Rhokyun R Department of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, - - 2013
We consider electroconvective fluid flows initiated by ion concentration polarization (ICP) under pressure-driven shear flow, a scenario often found in many electrochemical devices and systems. Combining scaling analysis, experiment, and numerical modeling, we reveal unique behaviors of ICP under shear flow: a unidirectional vortex structure, its height selection, and vortex ...
Schrag Anette E - - 2013
The neurobiological basis of psychogenic movement disorders remains poorly understood and the management of these conditions difficult. Functional neuroimaging studies have provided some insight into the pathophysiology of disorders implicating particularly the prefrontal cortex, but there are no studies on psychogenic dystonia, and comparisons with findings in organic counterparts are ...
Mast Alan E - - 2013
Dietary iron absorption is regulated by hepcidin, an iron regulatory protein produced by the liver. Hepcidin production is regulated by iron stores, erythropoiesis and inflammation, but its physiology has not been characterized when repeated blood loss occurs. Hepcidin was measured in plasma samples obtained from 114 first-time/reactivated (no blood donations ...
Fujiwara Keiko - - 2013
Since 1990, Boron Neutron Capture Therapy (BNCT) has been used for over 400 cancer patients at the Kyoto University Research Reactor Institute (KURRI). After BNCT, the patients are radioactive and their (24)Na and (38)Cl levels can be detected via a Na-I scintillation counter. This activity is predominantly due to (24)Na, ...
Robbins Amy Moorman - - 2013
Against previous critics' readings of Stein's Blood on the Dining-Room Floor as a failed attempt at the hard-boiled genre, this article argues for the many ways in which the novel re-writes the gothic/domestic detective story in a brilliant tour de force that frames all that is un-natural about heteronormative Victorian ...
Louis Elan D ED Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA. - - 2013
Environmental correlates for essential tremor (ET) are largely unexplored. The search for such environmental factors has involved the study of a number of neurotoxins. Harmane (1-methyl-9H-pyrido[3,4-b]indole) is a potent tremor-producing toxin. In two prior case-control studies in New York, we demonstrated that blood harmane concentration was elevated in ET patients ...
Yu Xuerong - - 2012
ABSTRACT: Study Design. A retrospective cohort study.Objective. To identify predictors of massive blood loss after scoliosis surgery.Summary of Background. Scoliosis surgery may be associated with considerable blood loss. Many blood conservation techniques have been used to reduce the allogeneic transfusion. An ability to identify patients with high risk for massive ...
Mutzbauer Till S - - 2012
Impairment of Eustachian tube function has been observed after hyperbaric oxygen treatment as well as after diving on oxygen used as breathing gas. The aim of the present study was to evaluate the influence of hyperbaric oxygen exposure on Eustachian tube ventilatory function and airflow characteristics of the nose. Six ...
Lee K F KF Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, - - 2012
The intermittent Pringle manoeuvre (IPM) is commonly applied during liver resection. Few randomized trials have addressed its effectiveness in reducing blood loss and the results have been conflicting. The present study investigated the hypothesis that IPM could reduce blood loss during liver resection by 50 per cent. Between May 2008 ...
Anders Katherine L - - 2012
Non-invasive specimens for dengue diagnosis may be preferable where venous blood is difficult to collect and/or process, such as community-based or remote settings or when sampling from young children. We evaluated the performance of oral swabs and dried blood spots (DBS), compared with plasma, in diagnosing acute dengue and screening ...
Wang Shen-Chih - - 2012
Plasma-containing products are given during the preanhepatic stage of liver transplant surgery to correct abnormal Thromboeslastogram (TEG) values and prevent blood loss due to coagulation defects. However, evidence suggests that abnormal TEG results do not always predict bleeding. We questioned what effect using higher TEG values to initiate treatment would ...
Imai Norio - - 2012
In this study, we evaluated the hemostatic effects of tranexamic acid (TNA), an antifibrinolytic drug, by examining the timing of its administration during total hip arthroplasty. One hundred seven patients being treated for osteoarthritis of the hip joint were randomly divided into 5 groups based on the timing of TNA ...
Elsedeek Mervat S-E-A - - 2012
OBJECTIVE: To evaluate the effect of preoperative administration of rectal misoprostol on blood loss during and after elective cesarean delivery. METHODS: A randomized controlled trial was conducted among 400 women scheduled for elective cesarean delivery. The study group (n=200) received 400μg of misoprostol. The control group (n=200) received placebo. Study ...
Zhang Wenjing - - 2012
The microenvironment of the cochlea is maintained by the barrier between the systemic circulation and the fluids inside the stria vascularis. However, the mechanisms that control the permeability of the intrastrial fluid-blood barrier remain largely unknown. The barrier comprises endothelial cells connected to each other by tight junctions and an ...
Achavanuntakul Kajohn - - 2012
PURPOSE: To evaluate the effect of clinical and tumor factors on operative blood loss during open radical hysterectomy and pelvic lymphadenectomy for early-stage cervical cancer. METHODS: Clinical, pathological, and operative data of 456 women with cervical cancer stage IA2-IIA who had open radical hysterectomy with bilateral pelvic lymphadenectomy (RHPL) from ...
Scully Christopher G - - 2012
Background:We designed this study to determine if 900 mL of blood withdrawal during spontaneous breathing in healthy volunteers could be detected by examining the time-varying spectral amplitude of the photoplethysmographic (PPG) waveform in the heart rate frequency band and/or in the breathing rate frequency band before significant changes occurred in ...
Clavé A - - 2012
Perioperative blood loss is a frequent cause of complications in total hip replacement (THR). The present prospective study assessed the efficacy of tranexamic acid (Exacyl(®)) in reducing blood loss in primary THR associated to rivaroxaban (Xarelto(®)) thromboprophylaxis. Tranexamic acid associated to rivaroxaban reduces blood loss. A prospective case-control study included ...
Radovanovic Ingrid - - 2012
Currently, there is very limited literature on the effect of long-term anticoagulants on total knee arthroplasty. The primary purpose of this study was to determine the effect of warfarin and clopidogrel on the transfusion rate, intra-operative blood loss, and postoperative blood loss for total knee arthroplasty. The secondary purpose was ...
McNally Stephen J SJ Department of Clinical Surgery, University of Edinburgh, Edinburgh, UK. - - 2012
Excessive blood loss during liver surgery contributes to postoperative morbidity and mortality and the minimizing of blood loss improves outcomes. This study examines pre- and intraoperative factors contributing to blood loss and identifies areas for improvement. All patients who underwent elective hepatic resection between June 2007 and June 2009 were ...
Stahl D L - - 2012
Surgical blood loss predicts peri-operative outcomes. We have developed and validated Blood Loss Scores to estimate peri-operative blood loss during major abdominal surgery. Surgical blood loss and changes in haemoglobin concentration were recorded intra- and postoperatively for 48 h in 100 patients undergoing radical prostatectomy. Data from the first group ...
McConnell Jamie - - 2012
Perioperative blood loss was compared in 136 patients (2 groups of 68 patients) who underwent total knee arthroplasty (TKA). Blood loss was significantly lower when using a computer-navigated technique in comparison to a method employing intramedullary femoral rods. Total blood loss was calculated from body weight, height and haematocrit change, ...
Heerwagen Søren T - - 2012
Purpose: The purpose of this study was to investigate if the immediate hemodynamic outcome of an endovascular intervention on a dysfunctional hemodialysis arteriovenous fistula is a prognostic factor for primary patency. Methods: This was a prospective observational study including 61 consecutive patients with dysfunctional arteriovenous fistulas referred to our endovascular ...
Schmutzhard Joachim - - 2012
Experimental murine malaria has been shown to result in significant hearing impairment. Microscopic evaluation of the temporal bones of these animals has revealed regular morphology of the cochlea duct. Furthermore, the known vascular pathologic changes being associated with malaria could not be found. Immunohistochemistry for ICAM1 showed a strong marking ...
Peach G - - 2011
INTRODUCTION: Kinking and endofibrosis of the iliac arteries are uncommon and poorly recognized conditions affecting young endurance athletes. Deformation or progressive stenosis of the iliac artery may reduce blood flow to the lower limb and adversely affect performance. The aim of this review was to examine the existing literature relating ...
Godin Gaston - - 2011
Findings about the efficacy of interventions promoting blood donation are scattered and sometime inconsistent. The aim of the present systematic review was to identify the most effective types of interventions and modes of delivery to increase blood donation. The following databases were investigated: MEDLINE/PubMed, PsycINFO, CINAHL, EMBASE, and Proquest Dissertations ...
Zhang Haoran - - 2011
PURPOSE: Studies have shown that tranexamic acid (TXA) reduces blood loss and transfusion need in patients undergoing total knee arthroplasty (TKA). However, no single study has been large enough to definitively determine whether the drug is safe and effective. We report a systematic review and meta-analysis of randomised controlled trials ...
Wikkelsoe A J - - 2011
Thrombelastography (TEG) and Thrombelastometry (ROTEM) are viscoelastic whole-blood assays evaluating the haemostatic capacity of blood. These devices are used in algorithms to guide transfusion of haemostatic blood components. The methods used for this study were systematic reviews with meta-analyses and trial sequential analyses of randomised clinical trials (RCTs) of TEG/ROTEM-based ...
Holly Crystal D - - 2011
BACKGROUND: Despite the ongoing need for blood donation, few people give blood. A common reason is concern about vasovagal symptoms. PURPOSE: The aim of this study was to evaluate the effectiveness of applied tension in reducing vasovagal symptoms during blood donation and the mechanisms of action. METHOD: Two hundred eighty-two ...
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