Search Results
Results 1 - 50 of 485
1 2 3 4 5 6 7 8 9 10 >
Gabbour Maya M Department of Medical Imaging #9, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 E. Chicago Ave., Chicago, IL, 60611, - - 2014
Doppler echocardiography (echo) is the reference standard for blood flow velocity analysis, and two-dimensional (2-D) phase-contrast magnetic resonance imaging (MRI) is considered the reference standard for quantitative blood flow assessment. However, both clinical standard-of-care techniques are limited by 2-D acquisitions and single-direction velocity encoding and may make them inadequate to ...
Gohean Jeffrey R JR *Windmill Cardiovascular Systems, Austin, Texas †Division of Cardiovascular Medicine, University of Texas Medical School at Houston and The Memorial Hermann Heart and Vascular Institute, Houston, Texas ‡Department of Mechanical Engineering, University of Texas at Austin, Austin, - - 2014
This paper describes the stroke volume selection and operational design for the TORVAD, a synchronous, positive-displacement ventricular assist device (VAD). A lumped parameter model was used to simulate hemodynamics with the TORVAD compared to those under continuous flow VAD support. Results from the simulation demonstrated that a TORVAD with a ...
Poudel Rajan - - 2014
In the fetus, there is a redistribution of cardiac output in response to acute hypoxemia, to maintain perfusion of key organs including the brain, heart and adrenal glands. There may be a similar redistribution of cardiac output in the chronically hypoxemic, intrauterine growth restricted (IUGR) fetus. Surgical removal of uterine ...
Gilchrist Philippe T PT McGill University, Canada. Electronic address: - - 2014
This study examined autonomic and hemodynamic processes associated with the development of naturally occurring vasovagal responses. Data from a study assessing the physiological correlates of an intervention to reduce vasovagal responses in blood donors were examined (Ditto et al., 2009). Ninety-eight participants were assigned randomly to groups that either practiced ...
Sakazaki Sayaka S Division of Pediatric Cardiology, Saitama Medical Center, Saitama Medical University, Kawagoe, Saitama, 350-8550, - - 2014
Hypoxia due to congenital heart diseases (CHDs) adversely affects brain development during the fetal period. Head circumference at birth is closely associated with neuropsychiatric development, and it is considerably smaller in newborns with hypoplastic left heart syndrome (HLHS) than in normal newborns. We performed simulation studies on newborns with CHD ...
Suwa Kenichiro K Division of Cardiology, Internal Medicine III, Hamamatsu University - - 2014
Background:The intra-left atrial (LA) blood flow from pulmonary veins (PVs) to the left ventricle (LV) changes under various conditions and might affect global cardiac function. By using phase-resolved 3-dimensional cine phase contrast magnetic resonance imaging (4D-Flow), the intra-LA vortex formation was visualized and the factors affecting the intra-LA flow dynamics ...
Wei Xufeng X Artificial Organs Laboratory, Department of Surgery, University of Maryland School of Medicine, Baltimore, MD 21201, - - 2014
Despite the significant contribution of the Fontan procedure to the therapy of complex congenital heart diseases, many patients progress to failure of their Fontan circulation. The use of ventricular assist devices (VADs) to provide circulatory support to these patients remains challenging. In the present study, a continuous axial-flow pump was ...
Midgett Madeline M Department of Biomedical Engineering and Knight Cardiovascular Institute, Center for Developmental Health, Oregon Health and Science University, 3303 SW Bond Avenue, CHH 13B, Portland, OR 97239, - - 2014
Altered blood flow during embryonic development has been shown to cause cardiac defects; however, the mechanisms by which the resulting haemodynamic forces trigger heart malformation are unclear. This study used heart outflow tract banding to alter normal haemodynamics in a chick embryo model at HH18 and characterized the immediate blood ...
Moraes José Mariano Soares de JM Botucatu Medical School, Sao Paulo State University, - - 2014
To verify the effects of different catecholamines on volemic expansion and on the autonomic nervous system in rabbits that were subjected to hemorrhage. Twenty four rabbits subjected to hemorrhage (with a 25% loss of blood volume) and were randomly divided into four experimental groups: 1) HEMO Group underwent replacement with ...
Marom Gil G Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY, - - 2014
The SynCardia total artificial heart (TAH) is the only Food and Drug Administration (FDA) approved device for replacing hearts in patients with congestive heart failure. It pumps blood via pneumatically driven diaphragms and controls the flow with mechanical valves. While it has been successfully implanted in more than 1300 patients, its ...
Grasser Erik Konrad EK Division of Physiology, Department of Medicine, Laboratory of Integrative Cardiovascular and Metabolic Physiology, University of Fribourg, Fribourg, Switzerland. Electronic address: - - 2014
The sale of energy drinks is often accompanied by a comprehensive and intense marketing with claims of benefits during periods of mental stress. As it has been shown that Red Bull negatively impacts human hemodynamics at rest, we investigated the cardiovascular and cerebrovascular consequences when Red Bull is combined with ...
Møller-Helgestad Ole K OK Department of Anaesthesiology & Intensive Care, Aarhus University Hospital, Denmark. Electronic address: - - 2014
Cardiogenic shock as a complication to an acute myocardial infarction has an unacceptably high death rate that has not changed for the last 15years. Mortality is partly related to organ hypoperfusion and mechanical assist devices are used for the most severe cases but we do not know which assist device ...
Kuan Yee Han YH a Department of Biomedical Engineering , National University of Singapore , - - 2014
The characterization of the bileaflet mechanical heart valves (BMHVs) hinge microflow fields is a crucial step in heart valve engineering. Earlier in vitro studies of BMHV hinge flow at the aorta position in idealized straight pipes have shown that the aortic sinus shapes and sizes may have a direct impact ...
Nemescu Dragos D Department of Obstetrics and Gynecology, University of Medicine and Pharmacy "Gr. T. Popa," Iasi, Romania; "Cuza Voda" Obstetrics & Gynecology Hospital, Iasi, Romania. Electronic address: - - 2014
We measured acoustic output, expressed as the thermal index (TI) and mechanical index (MI), during fetal echocardiography at the time of the first trimester scan. TI and MI were retrieved from the saved displays during gray-mode, high-definition color flow Doppler and pulsed-wave Doppler (tricuspid flow) ultrasound examinations of the fetal ...
Fleck Thilo T Department of Congenital Heart Disease/Pediatric Cardiology, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353, Berlin, Germany, - - 2014
Propofol is a short-acting, intravenously administered hypnotic agent which is used in procedural sedation in children. Propofol is known to decrease systemic vascular resistance, arterial blood pressure and can lead to desaturations and decreased systemic perfusion in children with cardiac shunting. This may result in a reduction in cerebral blood ...
Dori Guy G Department of Internal Medicine E, HaEmek Medical Center, Afula, Israel. Electronic address: - - 2014
Trans-mitral flow velocity (TMFV) examination is a standard echocardiographic measure for assessing diastolic function of the heart. Typically, the Doppler signal representing the early rapid filling phase of the left ventricle (LV), termed: E wave, is triangular. The ascending arm of the E wave (EWAA) represents blood accelerating into the ...
Abrams D D Division of Pulmonary, Allergy and Critical Care, Columbia University College of Physiciansand Surgeons, New York, New York, USA - - - 2014
Extracorporeal membrane oxygenation (ECMO) technology has undergone significant advancement in the last several years. These changes have led to more compact circuits that are increasingly efficient at gas exchange while decreasing the complication rates often associated with its use. The ability to remove carbon dioxide at relatively low flows has ...
Ramaswamy Sharan - - 2014
The ability to replicate physiological stress and hemodynamic conditions during in-vitro tissue development has been recognized as an essential aspect in the development of engineered heart valve tissues. Moreover, we have demonstrated that studies aiming to understand mechanical conditioning require separation of the major heart valve deformation loading modes: flow, ...
Hayakawa Akira A Department of Forensic Medicine, Hokkaido University Graduate School of Medicine, Sapporo, - - 2014
Previous studies have reported that thyroglobulin (Tg) concentrations in heart blood are high in cases of asphyxia caused by neck compression such as hanging, strangulation, and throttling and in those with fatal traumatic brain injuries. However, even in cases without these findings presumed to increase the Tg concentration in the ...
Moazami Nader N Department of Thoracic and Cardiovascular Surgery, Heart and Vascular Institute; Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address: - - 2014
Despite significant improved survival with continuous flow left ventricular assist devices (LVADs), complications related to aortic valve insufficiency, gastrointestinal bleeding, stroke, pump thrombosis, and hemolysis have dampened the long term success of these pumps. Evolution has favored a pulsatile heart pump to be able to deliver the maximum flow at ...
Capron Thibaut T Aix-Marseille Université, UMR 7339, CNRS, CRMBM (Centre de Résonance Magnétique Biologique et Médicale), 13385, Marseille, - - 2014
Although arterial spin labeling (ASL) has become a routinely performed method in the rodent heart, its application to the human heart remains challenged by low tissue blood flow and cardiac and respiratory motion. We hypothesized that an alternative steady-pulsed ASL (spASL) method would provide more efficient perfusion signal averaging by ...
Zhou Shan S Shan Zhou, Ian Welsby, Department of Anesthesiology, Duke University Medical Center 3094, Durham, NC 27710, United - - 2014
ABO blood type is one of the most readily available laboratory tests, and serves as a vital determinant in blood transfusion and organ transplantation. The ABO antigens are expressed not only on red blood cell membranes, determining the compatibility of transfusion, but also on the surface of other human cells, ...
Fadel Bahaa M BM King Faisal Specialist Hospital & Research Center, Riyadh, Saudi - - 2014
The flow pattern in the hepatic veins (HVs) is dependent on the cardiac cycle and right heart hemodynamics and influenced by the respiratory cycle and the liver parenchyma. Most disease states that affect the right heart alter the HV Doppler in a manner independent of the respiratory cycle. Some diseases ...
Chasovskyi K K Perfusiology, Ukrainian Children's Cardiac Center, Kyiv, Ukraine - - 2014
This study evaluates the hemoglobin-oxygen relationship and tissue perfusion during cardiopulmonary bypass (CPB) in neonates undergoing open-heart surgery using autologous umbilical cord blood or donor blood components. We compared perioperative hematocrit (Hct), fetal hemoglobin (HbF), p50O2, pH, pCO2, serum lactate, duration of mechanical ventilation and intensive care unit (ICU) length ...
Punn Rajesh R All authors: Division of Pediatric Cardiology, Department of Pediatrics, Stanford University School of Medicine, Lucile Packard Children's Hospital, Palo Alto, - - 2014
Currently, there are no established echocardiographic or hemodynamic predictors of mortality after weaning venoarterial extracorporeal membrane oxygenation in children. We wished to determine which measurements predict mortality. Over 3 years, we prospectively assessed six echo and six hemodynamic variables at 3-5 circuit rates while weaning extracorporeal membrane oxygenation flow. Hemodynamic ...
Salinas Manuel M Tissue Engineering, Mechanics, Imaging, and Materials Laboratory, Department of Biomedical Engineering, Florida International University, Miami, FL, - - 2014
Previous efforts in heart valve tissue engineering demonstrated that the combined effect of cyclic flexure and steady flow on bone marrow derived stem cell-seeded scaffolds resulted in significant increases in engineered collagen formation [Engelmayr et al. Cyclic flexure and laminar flow synergistically accelerate mesenchymal stem cell-mediated engineered tissue formation: Implications ...
Fadel Bahaa M BM King Faisal Specialist Hospital & Research Center, Riyadh, Saudi - - 2014
Doppler interrogation of blood flow in the hepatic veins (HVs) is a part of any comprehensive echocardiographic examination. Data derived from the HV Doppler provide a useful tool for the assessment of right heart function. Beyond its dependence on the cardiac cycle, right heart hemodynamics, and compliance of the liver ...
Ritman Erik L EL Mayo Clinic College of Medicine - - 2014
During WW2 Earl Wood was charged with elucidating the biomedical factors in acceleration-induced loss of consciousness (G-LOC) experienced by pilots in high performance aircraft. For this he developed devices for measurement and recording of blood pressure and tissue blood content. Those data lead to the design and fabrication of successful ...
Feeley Kyle P KP Department of Pathology, Division of Molecular and Cellular Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, - - 2014
Cardiovascular disease (CVD) is the leading cause of death worldwide and it exhibits a greatly increasing incidence proportional to aging. Atherosclerosis is a chronic condition of arterial hardening resulting in restriction of oxygen delivery and blood flow to the heart. Relationships between mitochondrial DNA damage, oxidant production, and early atherogenesis ...
Andrikopoulos Georgios K GK Sotirios P Gartaganis, Georgios K Andrikopoulos, Department of Ophthalmology, University of Patras Medical School, 26504 Patras, - - 2014
Pseudoexfoliation (PEX) syndrome is a well-recognized late-onset disease caused by a generalized fibrillopathy. It is linked to a broad spectrum of ocular complications including glaucoma and perioperative problems during cataract surgery. Apart from the long-known intraocular manifestations, PEX deposits have been found in a variety of extraocular locations and they ...
Dietrich Ann-Christin AC Institute of Biochemistry and Biology, University of Potsdam, Karl-Liebknecht-Straße 24-25, 14476 Potsdam, Germany; Institute for Molecular Biology, Medizinische Hochschule Hannover, Carl-Neuberg Straße 1, 30625 Hannover, Germany; Max Delbrück Center for Molecular Medicine, Robert-Rössle Straße 10, 13125 Berlin, - - 2014
During heart development, the onset of heartbeat and blood flow coincides with a ballooning of the cardiac chambers. Here, we have used the zebrafish as a vertebrate model to characterize chamber ballooning morphogenesis of the endocardium, a specialized population of endothelial cells that line the interior of the heart. By ...
O'Brien K M KM University of Alaska Fairbanks, Institute of Arctic Biology, PO Box 757000, Fairbanks, AK 99775, USA. Electronic address: - - 2014
Creatine kinase (CK; EC 2.7.3.2) functions as a spatial and temporal energy buffer, dampening fluctuations in ATP levels as ATP supply and demand change. There are four CK isoforms in mammals, two cytosolic isoforms (muscle [M-CK] and brain [B-CK]), and two mitochondrial isoforms (ubiquitous [uMtCK] and sarcomeric [sMtCK]). Mammalian oxidative ...
Delorme Yann T YT School of Mechanical Engineering, Purdue University, Lafayette, IN, United - - 2014
Univentricular heart disease is the leading cause of death from any birth defect in the first year of life. Typically, patients have to undergo three open heart surgical procedures within the first few years of their lives to eventually directly connect the superior and inferior vena cavae to the left ...
Alizadeh Mansour M Department of Mechanical Engineering, Iran University of Science & Technology, Tehran, - - 2014
The purpose of this study is to investigate the hemodynamic parameters of blood flow in a balloon as a part of a new type of cardiac assist device named AVICENA, which is implanted into the descending aorta to improve the strength of pumping blood flow in a poor-performing left ventricle. ...
Tsounis Michael M Department of Otorhinolaryngology/Head and Neck Surgery (M.T.), Queen's Medical Centre, Nottingham, United - - 2014
The aim of this study was to ascertain the most reliable objective measurement for the assessment of nasal patency by investigating the relationship between peak nasal inspiratory flow, peak oral inspiratory flow, and the nasal patency index in relation to the patient's subjective perception regarding nasal obstruction. Prospective cohort study. ...
Kobayashi Yoshiki - - 2014
Objective: Most asthmatics have been found to have rhinosinusitis (RS). Patients with ethmoid sinusitis, in particular, often suffer from an impaired sense of smell; this is clinically important and necessitates concurrent treatment for both asthma and RS. As a rational therapeutic strategy, we focused on a fine particle HFA-134abeclomethasone dipropionate ...
Nobahar Mohammad Rezvan MR Department of Cardiac Anesthesia (Anesthesiology in Cardiac Surgery), Shahid Modares Hospital, Saadat Abad, Tehran, - - 2014
Acute normovolemic hemodilution (ANH) and preoperative autologous blood donation (PABD) have questionable efficacy, viral and bacterial infection risks, intermittent blood shortages as homeostasis problem, electrolyte and hemodynamic disturbances. In this cross sectional survey, we studied 70 patients undergoing open heart coronary artery bypass grafts [CABG] and different valvular replacement 1 ...
Ghezzi Chiara E CE Department of Mining and Materials Engineering, McGill University, Montreal, Quebec, Canada H3A - - 2014
Airway tracts serve as a conduit of transport in the respiratory system. Architecturally, these are composed of cartilage rings that offer flexibility and prevent collapse during normal breathing. To this end, the successful regeneration of an airway tract requires the presence of differentiated chondrocytes and airway smooth muscle cells. This ...
Zhao Kai K Monell Chemical Senses Center, Philadelphia, PA; Department of Otolaryngology, Thomas Jefferson University, Philadelphia, - - 2014
Nasal airflow is essential for the functioning of the human nose. Given individual variation in nasal anatomy, there is yet no consensus what constitutes normal nasal airflow patterns. We attempt to obtain such information that is essential to differentiate disease-related conditions. Computational fluid dynamics (CFD) simulated nasal airflow in 22 ...
Kirtsreesakul Virat V Department of Otolaryngology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, - - 2014
Although nasal peak flow measurements have been proposed as a simple alternative method to assess nasal patency, which of nasal peak expiratory flow or nasal peak inspiratory flow (NPEF/NPIF) or the peak expiratory flow index or peak inspiratory flow index (PEFI/PIFI; the ratios between nasal and oral PEF or nasal ...
Hirose Kayo K Department of Pharmacology, Institute of Health Biosciences, the University of Tokushima Graduate - - 2014
A 71-year-old woman had an episode of syncope due to hypoglycemia of 27 mg/dl. She was diagnosed with insulinoma and scheduled for laparoscopic enucleation along with the use of an artificial endocrine pancreas (STG-22, Nikkiso Co., Ltd., Tokyo, Japan). Anesthesia was maintained with sevoflurane and remifentanil. Her blood glucose level ...
Linask Kersti K KK Department of Pediatrics, Morsani College of Medicine, Children's Research Institute, University of South Florida Health St. Petersburg, FL, - - 2014
Analyses of cardiovascular development have shown an important interplay between heart function, blood flow, and morphogenesis of heart structure during the formation of a four-chambered heart. It is known that changes in vitelline and placental blood flow seemingly contribute substantially to early cardiac hemodynamics. This suggests that in order to ...
Wang Yong Y Department of Mechanical & Aerospace Engineering, University of California, Irvine, CA 92697, - - 2013
The fluid dynamical properties of the air flow in the upper airway (UA) are not fully understood at present due to the three-dimensional (3D) patient-specific complex geometry of the airway, flow transition from laminar to turbulent and flow-structure interaction during the breathing cycle. It is quite difficult at present to ...
Oreroğlu Ali Rıza AR Plastic Reconstructive and Aesthetic Surgery Department, Prof. Dr. A. İlhan Özdemir Giresun State Hospital, Atatürk Blvd. No. 323, 28100, Teyyaredüzü, Giresun, Turkey, - - 2013
The combination of dorsal nasal reconstruction and camouflage of surface irregularities is an important step in rhinoplasty. We hereby present our technique of delivering diced cartilage in combination with bone dust to the nasal dorsum using the patient's blood as a carrier. We advocate use of an autologous material (blood) ...
Miller Vincent J - - 2013
Traditionally, pausing chest compressions during airway management in a cardiac arrest has been the accepted norm. However, updated American Heart Association and the European Resuscitation Council guidelines for Advanced Cardiac Life Support emphasize reducing pauses in chest compressions, often referred to as "no-flow time," to improve return of spontaneous circulation. ...
Rubin Sarah - - 2013
High-flow humidified nasal cannula is often used to provide noninvasive respiratory support in children. The effect of high-flow humidified nasal cannula on effort of breathing in children has not been objectively studied, and the mechanism by which respiratory support is provided remains unclear. This study uses an objective measure of ...
Yadav Santosh K SK Department of Neurobiology, University of California at Los Angeles, Los Angeles, CA 90095, - - 2013
Obstructive sleep apnea (OSA) is a condition characterized by upper airway muscle atonia with continued diaphragmatic efforts, resulting in repeated airway obstructions, periods of intermittent hypoxia, large thoracic pressure changes, and substantial shifts in arterial pressure with breathing cessation and resumption. The hypoxic exposure and hemodynamic changes likely induce the ...
Ryan Clodagh M - - 2013
Both obstructive sleep apnoea (OSA) and impaired cerebrovascular reactivity (CVR) are associated with an increased risk of stroke. We therefore hypothesised that CVR would be decreased in OSA patients. Since OSA is associated with altered endothelial function and this dysfunction may in turn lead to impaired CVR, we further hypothesised ...
Lintermann Andreas - - 2013
The flow in the human nasal cavity is of great importance to understand rhinologic pathologies like impaired respiration or heating capabilities, a diminished sense of taste and smell, and the presence of dry mucous membranes. To numerically analyze this flow problem a highly efficient and scalable Thermal Lattice-BGK (TLBGK) solver ...
Paspala Asimina - - 2013
Bilateral vocal cord paralysis can produce severe airway obstruction, leading to acute respiratory failure. Discriminating the pathology of the upper airway from chronic obstructive diseases of the lower airways often presents a challenge for clinicians in the Emergency Department. To underlie the value of clinical examination and flow-volume loops in ...
1 2 3 4 5 6 7 8 9 10 >