A group of clinical senile dementia patients underwent a series of cerebrovascular examinations. Some of them were standard examinations (fundus oculi, electroencephalogram, rheoencephalogram, cerebral angiogram and pneumonencephalogram) while the others were studying regional cerebral blood flow (rCBF) and modification of flow under fonctional tests (hypercapnia, hypocapnia and intravenous injection of ...

Cerebral oxygen uptake was correlated with electroencephalographic (EEG) frequency and amplitude in 87 isolated canine brains. Group I (71 brains) was perfused with diluted blood and Group II (16 brains) was perfused with whole blood equilibrated with oxygen at various partial pressures. The EEG's were classified as follows: A, highest ...

The effect of prostaglandin E1 on regional cerebral blood flow (rCBF) was studied with the intra-arterial 133Xe method in ten awake patients under local anesthesia. Measurements were taken from 16 areas of a hemisphere in seven patients, from 35 areas of a hemisphere in two patients and from 256 areas ...

In 32 chronic patients the EEG in temporal and occipito-parietal bipolar leads was analyzed with a manual method giving a period frequency index. The cerebral oxygen uptake (CMRO2) was calculated from the arteriovenous oxygen difference between samples from the internal carotid artery and the jugular bulb respectively, and from measurement ...

A change of the heart rate in patients with complete AV-block and externally controllable cardiac pace-makers was earlier shown to influence cerebral function, as measured by psychological tests. To determine whether this influence manifests itself in the EEG, 9 patients aged 43-83 years were examined, all having complete AV-block and ...

EEG and neuropsychological evaluation of 66 polydrug users revealed that 43% had EEG abnormalities and 45% had neuropsychological impairment 3 weeks after admission to a polydrug study unit. At 5-month follow-up, 27% of 30 retested subjects were still impaired neuropsychologically. Impairment may be related to extensive involvement with sedatives, alcohol, ...

Blood levels and electroencephalographic (EEG) data were collected for 2 hr after single oral doses of bromazepam (9 mg), diazepam (10 mg), and placebo in 13 male adult volunteers. Both drugs caused an increase in beta activity (above 13 Hz) and a decrease in alpha activity (9 to 11 Hz) ...

Interictal regional cerebral blood flow was determined in 11 adult patients with partial epilepsy and lateralized electroencephalographic abnormalities by means of the xenon 133 intracarotid injection method. A hemispheric area demonstrating significantly low regional cerebral blood flow values as compared with the hemispheric mean cerebral blood flow was observed in ...

A model is described for study of the cerebral edema associated with the contusion of closed head injury. A Remington Humane Stunner was used to deliver blows to the skulls of anesthetized cats. Forty-eight hours after impact, those cats demonstrating a one-sided contusion were tested for cerebral edema by measurement ...

A boy with intractable siezures that had progressed to about 30 a day underwent complete disconnection of the cerebral hemispheres in January 1972. Using microsurgical technique, we followed the path described by Bogen and Vogel requiring division of the corpus callosum from rostrum to splenium, the anterior commisure, one fornix, ...

Cranial blood flow, mean cranial transit time and cranial blood volume were measured by the intravenous RISA technique in 10 patients with cerebral transient ischemic attacks (TIA) at the various time intervals from the onset of last attack. Cranial blood flow was subnormal in 5 out of 11 determinations and ...

Twenty-four patients of comparable age, blood pressure, and degree of dementia were classified by an "Ischemic Score" based on clinical features into "multi-infarct" and "primary degenerative" dementia. Regional cerebral blood flow (CBF) was measured by the intracarotid xenon 133 method. Both groups showed a decreased proportion of rapidly clearing brain ...

This critical survey of the current means of determining cerebral death has indicated certain shortcomings in each of the sets of criteria currently in use. It is apparent that criteria applied at a point in time and based upon a single organ system-clinical history and findings, EEG examinations or cerebral ...

The effects of positive acceleration on the CNS were studied by applying negative pressure to the lower body (LBNP) of unanesthetized rabbits. The LBNP which can simulate well the effects of positive acceleration induced high voltage slow bursts with amplitude 600-800 microV and frequency of 2-3 Hz in the EEG ...

A highly purified preparation of staphylococcal enterotoxin B was administered intravenously, 1 mg/kg, to rhesus monkeys. Electroencephalograms (EEG) were recorded from electrodes attached to the skin or implanted on the dura. The dose of toxin employed consistently produced a sequence of vascular collapse followed by death; in control studies, animals ...