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Lafeuillade Bruno B Direction of Advanced Therapies, Human Products and Vaccines, French National Agency of Medicine and Health Products Safety-ANSM (ex Afssaps), Saint-Denis, - - 2014
Regarding blood safety, transfusion-transmitted bacterial infection (TTBI) remains the most frequent infectious risk. The incidence of these episodes needs to be assessed and updated frequently to accurately manage this risk. TTBIs were reported by the French network of local correspondents in each hospital and blood center. The regional coordinator managed ...
Dhariwal Sukhjit K - - 2014
An important cause of maternal morbidity and direct maternal death is obstetric haemorrhage at caesarean section. Concerns regarding allogeneic blood safety, limited blood supplies and rising health costs have collectively generated enthusiasm for the utility of methods intended to reduce the use of allogeneic blood transfusion in cases of haemorrhage ...
Winstanley H F HF MACSI, Department of Mathematics and Statistics, University of Limerick, Limerick, Republic of Ireland, - - 2014
We present a model of biofilm growth in a long channel where the biomass is assumed to have the rheology of a viscous polymer solution. We examine the competition between growth and erosion-like surface detachment due to the flow. A particular focus of our investigation is the effect of the ...
Li Aihong A Department of Medical Biosciences, Clinical Chemistry, Umeå University Hospital, Umeå University , Umeå , - - 2014
Background. The Sysmex XE-5000 offers automated quantification of red blood cells and white blood cells (WBCs) in body fluids, with differentiation of polymorphonuclear cells (PMNs) and mononuclear cells (MNCs). Methods. We evaluated automated WBC counting in cerebrospinal fluid (CSF) using the body fluid mode on the Sysmex XE-5000, comparing it ...
Rau Mandy Kim MK Department of Neuroradiology, Eberhard Karls University, Hoppe-Seyler-Str. 3, 72076, Tübingen, - - 2014
Several studies evaluated the predictive value of dynamic susceptibility contrast enhanced (DSC) imaging and arterial spin labeling (ASL) with regard to histological grade. Yet still less is known about their significance in terms of patients prognosis. Our purpose was to evaluate the agreement between them and the prognostic value of ...
Berra Lorenzo L Massachusetts General Hospital, Anesthesia & Critical Care , 55 Fruit Street , Boston, Massachusetts, United States, Harvard Medical School ; - - 2014
Rationale: Transfusion of erythrocytes stored for prolonged periods is associated with increased mortality. Erythrocytes undergo hemolysis during storage and after transfusion. Plasma hemoglobin scavenges endogenous nitric oxide leading to systemic and pulmonary vasoconstriction. Objectives: We hypothesized that transfusion of autologous blood stored for 40-days would increase the pulmonary artery pressure ...
Wang Miao M Department of Anesthesiology, West China Hospital, Sichuan University, No 37, Guo-xue-xiang Street, Chengdu, 610041, Sichuan, - - 2014
As the blood flow volume in non-dependent lung composed the primary part of the intrapulmonary shunt during one-lung ventilation (OLV), the shunt fraction (SF) during OLV can be represented by the ratio of blood flow volume in non-dependent lung to the bilateral lung. The purpose of this study is to ...
Müller M M Clinic of Small Animal Medicine, Ludwig Maximilians University, Veterinaerstrasse 13, 80539 Munich, - - 2014
The occurrence of nucleated red blood cells (NRBC) in the peripheral blood of critically ill human patients is associated with increased mortality. In dogs, the presence of NRBCs in peripheral blood has been used as a sensitive and specific marker of complications and outcome associated with heatstroke. However, no study ...
Keir Amy - - 2014
Adverse transfusion reactions in the neonatal population are poorly understood and defined. The incidence and pattern of adverse effects due to red blood cell (RBC) transfusion are not well known, and there has been no systematic review of published adverse events. RBC transfusions continue to be linked to the development ...
Warrington Junie P JP Department of Physiology & Biophysics, University of Mississippi Medical Center, Jackson, - - 2014
Cerebrovascular events contribute to ~40% of preeclampsia/eclampsia-related deaths, and neurological symptoms are common among preeclamptic patients. We previously reported that placental ischemia, induced by reducing utero-placental perfusion pressure, leads to impaired myogenic reactivity and cerebral edema in the pregnant rat. Whether the impaired myogenic reactivity is associated with altered cerebral ...
Pietrzak Bronisława - - 2014
Transfusion-related acute lung injury (TRALI) is a rare, but potentially fatal, complication of blood product transfusion, manifesting as acute respiratory distress syndrome. In most cases, TRALI is associated with massive transfusion of fresh frozen plasma and platelets. A 38-year-old-woman at 40 weeks gestation was admitted to hospital with spontaneous labor ...
Pearson G A GA Department of Obstetrics and Gynaecology, Plymouth Hospitals NHS Trust, Plymouth, PL6 8DH, United Kingdom. Electronic address: - - 2014
Attitudes to acute blood loss and transfusion have changed during the last 40 years. This study observed the trends in blood loss and transfusion rates at caesarean section during that period to identify any trends between 1976 and 2006. Prospective analysis of clinical notes of women delivered by caesarean sections ...
Li Li L Department of Psychology, The University of Hong Kong, Hong Kong, Special Administrative Region of the People's Republic of China - - 2014
Although previous studies have shown that people use both optic flow and target egocentric direction to walk or steer toward a goal, it remains in question how enriching the optic flow field affects the control of heading specified by optic flow and the control of target egocentric direction during goal-oriented ...
Baby Prathap Moothamadathil PM Department of Physiology, Melaka Manipal Medical College, Manipal campus, Manipal University, Karnataka, - - 2014
Blood volume measurement though important in management of critically ill-patients is not routinely estimated in clinical practice owing to labour intensive, intricate and time consuming nature of existing methods. The aim was to compare blood volume estimations using trivalent chromium [(51)Cr(III)] and standard Evans blue dye (EBD) method in New ...
Del Pozzi Andrew T AT Departments of Pediatrics and Physiology, New York Medical College, - - 2014
Hyperventilation and reduced cerebral blood flow velocity can occur in postural tachycardia syndrome (POTS). We studied orthostatically intolerant patients, with suspected POTS, with a chief complaint of upright dyspnea. On the basis of our observations of an immediate reduction of cerebral blood flow velocity with orthostasis, we hypothesize that the ...
Wieling W W Departments of Internal Medicine, Academic Medical Centre University of Amsterdam, Amsterdam, The - - 2014
Standing upright challenges the cardiovascular system as the pull of gravity displaces about 70% of the circulating blood volume to below heart level, much of it to the compliant veins of the dependent limbs and the pelvic organs. In patients with autonomic failure due to neurodegenerative diseases, the normal cardiovascular ...
Kaya Zekeriya Z Department of Cardiology, Faculty of Medicine, Harran University; Şanlıurfa-Turkey. - - 2014
To investigate mean platelet volume (MPV) levels in patients with coronary slow flow (CSF). 465 stable angina pectoris cases with angiographically normal coronary arteries were recruited [coronary slow flow group (n=76), control group (n=389)] in the observational retrospective cohort study. Clinical, biochemical and demographic variables including MPV were noted and ...
Rose Jason P JP University of Toledo, Toledo, - - 2014
Blood is a valuable resource, but most people do not donate. One deterrent to blood donation is the anticipation of vasovagal symptoms (e.g., dizziness, nausea, and fainting), despite the fact that such symptoms typically affect a small proportion of donors. The current research examined norm perceptions regarding vasovagal symptom experiences ...
Ditto Blaine - - 2014
Objective: Observing or hearing about illness in another person can lead to reports of similar symptoms. Reports can occasionally be widespread. However, it has been difficult to document whether this is the result of genuine illness or the expression of anxiety with physical terminology. This study examined the effects of ...
Phillips Aaron A AA 1University of British - - 2014
Individuals with spinal cord injury (SCI) above the T6 spinal segment suffer from orthostatic intolerance. How cerebral blood flow (CBF) responds to orthostatic challenges in SCI is poorly understood. Furthermore, it is unclear how interventions meant to improve orthostatic tolerance in SCI influence CBF. This study aimed to examine: 1) ...
Tugba Barsan B 1 Department of Pediatric Cardiology, Eskisehir Osmangazi University, Eskisehir, - - 2014
Introduction: We aimed to evaluate changes in the cerebral blood supply in children during vasovagal syncope and to clarify the diagnostic value of transcranial Doppler for vasovagal syncope. Materials and methods: Patients were divided into three groups. Group 1 consisted of 31 patients who were symptomatic and whose head-up tilt ...
Cheng Ran R University of Kentucky, Department of Biomedical Engineering, Lexington, Kentucky - - 2014
ABSTRACT. Significant drops in arterial blood pressure and cerebral hemodynamics have been previously observed during vasovagal syncope (VVS). Continuous and simultaneous monitoring of these physiological variables during VVS is rare, but critical for determining which variable is the most sensitive parameter to predict VVS. The present study used a novel ...
Sirek Adam S AS Wyle Integrated Science and Engineering, Houston, TX, USA. - - 2014
Ocular changes have been noted during long-duration spaceflight; we studied central retinal artery (CRA) blood flow using Doppler before, during, and after long-term microgravity exposure in astronauts compared with data from a control group of nonastronauts subjected to head-down tilt (HDT). Available Doppler spectra of International Space Station (ISS) crewmembers ...
Endo Ayumi A Department of Pediatrics and Child Health, Nihon University School of Medicine, 30-1 Oyaguchi-Kamicho, Itabashi-ku, Tokyo, 173-8610, - - 2014
Orthostatic dysregulation (OD) has been classified into subtypes by heart rate and blood pressure; however, the hemodynamics of brains have not yet been revealed. Therefore, we investigated changes in cerebral blood flow and oxygenation during an active standing test to clarify the pathophysiology of two subtypes: postural tachycardia syndrome (POTS) ...
Miyake Takahiro T Department of Rehabilitation Medicine, Wakayama Medical University, School of Medicine, 811-1 Kimiidera, 641-8509 Wakayama City, Wakayama, - - 2014
The purpose of this study was to define common carotid blood flow (CBF), cardiovascular and endocrine responses during head-up tilt (HUT) in patients with acute cerebrovascular diseases (CVD). In 31 male patients with acute CVD (damage of the supratentorial area) and 21 age-matched control male subjects, we measured CBF, mean ...
Borzova Elena E BMRC, University of East Anglia, Norwich, - - 2014
The absolute basophil count (cells/L) can be determined by manual counting of peripheral blood smears or using cell-counting chambers as well as by automated hematology analyzers and fluorescence flow cytometry. Manual basophil counting of peripheral blood smears is currently regarded as the reference method, although the limitations of this method ...
Wankah Paul Nji PN Faculty of Medicine and Biomedical Sciences Yaoundé, University of Yaoundé 1, P.O Box 1364, Yaoundé, - - 2014
Abnormal hemograms are common manifestations and important predictive tools for morbidity in the human immunodeficiency virus (HIV) infection. Few studies have been reported on the blood profile of HIV antiretroviral therapy (ART) naive subjects, therefore this study aimed to quantitatively and qualitatively describe the blood cell profile of HIV ART ...
Alavi-Moghaddam Mostafa M Department of Emergency Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, - - 2014
Background. Blood transfusion is the cornerstone of therapy for many serious and common diseases. This study was performed to assess blood transfusion practice before and after implementation of type and screen protocol in emergency department of a university affiliated hospital in Iran, 2012-2013. Methods. An audit was studied before and ...
Hashimdeen S H - - 2013
This study investigates the effect of print head design on the electrohydrodynamic printed resolution of silk fibroin. Needles with large orifices measuring at 800μm were used to build five different print heads. The print heads were manufactured, tested, and optimized using four different silk fibroin solution concentrations of 10wt.%, 15wt.%, ...
Phillips Aaron A - - 2013
Significant cardiovascular and autonomic dysfunction occurs following a spinal cord injury (SCI). Two major conditions arising from autonomic dysfunction are orthostatic hypotension and autonomic dysreflexia (i.e., severe acute hypertension). Effective regulation of cerebral blood flow (CBF) is essential to offset the potential drastic alterations in cerebral perfusion pressure. In the ...
Mezei Zsolt - - 2013
Demyelination in multiple sclerosis (MS) may cause damage to the vegetative nervous system. Our objective was to examine cerebral autoregulation assessed via blood pressure and cerebral blood flow velocity fluctuations during head-up tilt table testing. We also investigated the effects of high-dose intravenous corticosteroid treatment. Transcranial Doppler registration of middle ...
Ichikawa D - - 2013
The incidence of orthostatic intolerance is elevated in endurance-trained individuals. We sought to test the hypothesis that aerobic endurance training is associated with an attenuated control of the cerebral vasculature. Endurance trained (ET, n = 13) and age-matched untrained (UT, n = 11) individuals (peak O2 consumption, mean ± SEM; 63 ± 1 vs 42 ± 1 mL/min/kg, P < 0.05) were examined ...
Perlmuter Lawrence C LC Department of Psychology, Rosalind Franklin University of Medicine and Science, North Chicago, IL, - - 2013
The magnitude of increase in systolic blood pressure in response to the shift from supine to upright posture is considered to reflect the adequacy of orthostatic regulation. Orthostatic integrity is largely maintained by the interaction between the skeletal muscle pump, neurovascular compensation, neurohumoral effects, and cerebral blood flow regulation. Various ...
Stewart Julian M JM Departments of Pediatrics, Physiology, and Medicine, The Maria Fareri Children’s Hospital, NY, USA. - - 2013
The autonomic nervous system, adequate blood volume, and intact skeletal and respiratory muscle pumps are essential components for rapid cardiovascular adjustments to upright posture (orthostasis). Patients lacking sufficient blood volume or having defective sympathetic adrenergic vasoconstriction develop orthostatic hypotension (OH), prohibiting effective upright activities. OH is one form of orthostatic ...
van Dijk J Gert - - 2013
The definition of syncope has clinical and pathophysiological parts. The clinical part is that syncope is a form of transient loss of consciousness (TLOC), while the pathophysiological element is that syncope differs from other forms of TLOC by virtue of the basis of true syncope - specifically cerebral hypoperfusion. As ...
Davis Philip - - 2013
An activity profile of competitive 3 × 2-min novice-level amateur boxing was created based on video footage and postbout blood [La] in 32 male boxers (mean ± SD) age 19.3 ± 1.4 y, body mass 62.6 ± 4.1 kg. Winners landed 18 ± 11 more punches than losers by applying ...
Foulkes Andrew J - - 2013
Here we examine the relationship between the perception of heading and flow parsing. In a companion study we have investigated the pattern of dependence of human heading estimation on the quantity (amount of dots per frame) and quality (amount of directional noise) of motion information in an optic flow field. ...
Kountouriotis Georgios K GK Institute of Psychological Sciences, University of Leeds, Leeds LS2 9JT, UK; and Institute for Transport Studies, University of Leeds, Leeds LS2 9JT, UK; e-mail: - - 2013
Optic flow can be used by humans to determine their direction of heading as well as controlling steering. Dot-flow displays have been widely used to investigate these abilities but it is unclear whether photorealistic textures would provide better information for controlling high-speed steering. Here, we examine the accuracy of heading ...
Tsai Keng-Kuang - - 2012
The regulation of nasal mucosa blood flow (NMBF) is affected by multiple factors, such as the autonomic nervous system, medications, temperature, humidity, endocrine, even emotional stress and vision. The effects of postural changes on NMBF have been described in numerous studies. However, the results are far from consistent due to ...
Ogawa Yojiro - - 2013
Diuretic-induced mild hypovolemia with hemoconcentration reportedly improves dynamic cerebral autoregulation, whereas central hypovolemia without hemoconcentration induced by lower body negative pressure (LBNP) has no effect or impairs dynamic cerebral autoregulation. This discrepancy may be explained by different blood properties, by degrees of central hypovolemia, or both. We investigated the effects ...
Zhang Hong-Liang - - 2012
OBJECTIVE: Cerebral autoregulation (CA) is the mechanism by which constant cerebral blood flow is maintained despite changes in cerebral perfusion pressure. CA can be evaluated by dynamic monitoring of cerebral blood flow velocity (CBFV) with transcranial Doppler sonography (TCD). The present study aimed to explore CA in chronic anxiety. METHODS: ...
Nagatani Kimihiro - - 2012
Data on the optimal head position for patients with acute ischemic stroke are unavailable. We evaluated the effects of mild head-down tilt (HDT) on cerebral blood flow (CBF) in mice during bilateral common carotid artery occlusion (BCCAO). We used mice with BCCAO (35 minutes) and divided these into 2 groups ...
Nagafusa Yuko - - 2012
BACKGROUND: Single-photon emission computed tomography (SPECT) is used as an ancillary diagnostic tool in clinical psychiatry. A variety of SPECT studies has been conducted on the findings and the factors that affect the findings, and there is a possibility that age has an effect on cerebral blood flow. We used ...
Warren Paul A PA School of Psychological Sciences, The University of Manchester, Manchester, UK. - - 2012
We have recently suggested that neural flow parsing mechanisms act to subtract global optic flow consistent with observer movement to aid in detecting and assessing scene-relative object movement. Here, we examine whether flow parsing can occur independently from heading estimation. To address this question we used stimuli comprising two superimposed ...
Slapak Colleen - - 2011
ATSO is in a unique position to break down organizational silos between hospitals and blood centers through the development of a collaborative relationship between the two entities. Use of the TSO as blood center staff centralizes the role into a consultative position thereby retaining the independence of the hospitals. The ...
Que Yanhong - - 2011
The aim of this study is to evaluate the contrast-enhanced ultrasound (CEUS) features of peritoneal metastases. Unenhanced ultrasound and CEUS were conducted in 25 patients who had confident diagnoses of peritoneal metastases after ultrasound-guided biopsies of peritoneum. B-mode sonograms, color Doppler, CEUS pattern and quantitative analysis of blood perfusion in ...
Varma Neelam - - 2011
Applications of flow cytometry in pediatric cancers have expanded substantially in recent years. In acute leukemias, the commonest childhood cancer, flow cytometry can now define complex antigenic profiles that are associated with specific cytogenetic/molecular defects and can also directly identify BCR-ABL fusion protein. Flow cytometry based scoring system has been ...
Bommer Martin - - 2011
BACKGROUND: Cerebrospinal fluid samples with doubtful morphologic interpretation are a common problem in the workup of patients with clinical signs for leptomeningeal disease. The authors report on the combination of morphology and flow cytometry in the diagnosis of leptomeningeal disease in patients with radiological, clinical, or cytological findings suspicious for ...
Schmidt René - - 2011
Preoperative embolization of vertebral metastases has been shown to lower intraoperative blood loss. Nevertheless, excessive up to life-threatening blood loss can occur despite embolization. We therefore decided to evaluate possible parameters for predicting significant blood loss in a surgically homogeneous group of patients with vertebral metastases. Patients with vertebral metastases ...
Yang Dal Mo - - 2010
The purpose of this study was to describe the sonographic findings of acute vasitis. This was a retrospective analysis of 12 cases of acute vasitis. The following gray scale and color Doppler sonographic features were analyzed: location, echogenicity of the lesion, presence of hydrocele, epididymal involvement, and blood flow within ...
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