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Kitau Jovin - - 2014
Long-lasting insecticide treated blankets (LLIBs) may provide additional protection against malaria where use of long lasting insecticidal nets (LLIN) is low or impractical such as in disaster or emergency situations. Initial efficacy testing of a new candidate LLIB was carried out at LSHTM and KCMUCo, before and after washing, in ...
Tripolino Cesare C Dipartimento di Medicina Sperimentale e Clinica, "Magna Græcia" University, Catanzaro, - - 2014
Peripheral artery occlusive disease (PAOD) is associated with increased cardiovascular risk (CVR). Recently it has been reported that also the increased stiffness of lower limb arteries is associated with increased CVR. In particular, subjects with poorly compressible arteries (PCA) appear to have a CVR even higher than that of subjects ...
Song Howard K HK Division of Cardiothoracic Surgery, Oregon Health & Science University, Portland, Oregon. Electronic address: - - 2014
Perioperative red blood cell transfusion is associated with adverse outcomes after cardiac operations. Although restrictive transfusion protocols have been developed, their safety and efficacy are not well demonstrated, and considerable variation in transfusion practice persists. We report our experience with a restrictive transfusion protocol. We analyzed the outcomes in 409 ...
Winfield Laramie S LS Steinbeck Country Equine Clinic, 15881 Toro Hills Ave, Salinas, CA - - 2014
Case Description-A 23-year-old Thoroughbred mare was evaluated because of a coagulopathy causing hemoperitoneum, hematomas, and signs of blood loss-induced anemia. Clinical Findings-The mare had tachycardia, pallor, hypoperfusion, and a large mass in the right flank. The mass was further characterized ultrasonographically as an extensive hematoma in the body wall with ...
Alotaibi Ghazi S - - 2014
Background Sickle cell disease (SCD) is associated with perioperative vascular (SCD-related) and non-vascular complications. To minimize perioperative complications during elective surgery, either exchange blood transfusion or simple blood transfusion can be used. We systematically reviewed the literature and meta-analyzed randomized and observational trials comparing exchange transfusion to simple transfusion, as ...
Junge Kristin M KM Helmholtz Centre for Environmental Research - UFZ, Leipzig, Department of Environmental Immunology, Germany; McMaster University, Division of Clinical Immunology and Allergy, Hamilton, ON, Canada. Electronic address: - - 2014
Cord blood eosinophil/basophil progenitor cells (Eo/B) of high risk infants have been shown to predict respiratory illnesses in infancy. Here we investigated this association in a population-based cohort. Furthermore, we analysed whether newborns Th1/Th2 balance and prenatal environmental exposure impact Eo/B recruitment. In a sub-cohort of the LINA study cord ...
Park Sung Jun SJ Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, - - 2014
The establishment of reliable markers to monitor adequate tissue perfusion during extracorporeal life support is clinically important to improve outcomes. We evaluated 115 consecutive adult patients (aged 61.7 ± 13.4 years, 59 female patients) undergoing extracorporeal life support to manage low cardiac output syndrome after major cardiac surgery. The blood ...
Phasomkusolsil Siriporn - - 2014
Colonization of members of the Anopheles Hyrcanus Group is required to facilitate a better understanding of their roles in the epidemiology, vector competence, transmission potential, and maintenance of vivax malaria in the Republic of Korea (ROK). A total of 158 resting blood-fed wild caught Anopheles species were collected on August ...
Braz Ana Carolina Garcia AC Universidade de São Paulo, Ribeirão Preto, SP, Brazil, Universidade de São Paulo (USP), Ribeirão Preto, SP, - - 2014
the Blood Donation Reactions Inventory (BDRI) scale was proposed as part of a study about the predictors of psychological reactions in volunteer blood donors, as uncomfortable reactions are associated with a lower probability to return for further donations. to translate the Inventory into Brazilian Portuguese and evaluate its psychometric properties ...
Loureiro Paula P Universidade de Pernambuco, Faculdade de Ciências Médicas, Recife, PE, Brazil, Faculdade de Ciências Médicas, Universidade de Pernambuco (UPE), Recife, PE, Brazil ; Fundação Hemope, Recife, PE, Brazil, Fundação Hemope, Recife, PE, - - 2014
The Retrovirus Epidemiology Donor Study (REDS) program was established in the United States in 1989 with the purpose of increasing blood transfusion safety in the context of the HIV/AIDS and human T-lymphotropic virus epidemics. REDS and its successor, REDS-II were at first conducted in the US, then expanded in 2006 ...
Schrauf Christine M - - 2014
It is not surprising that there is no documented evidence supporting a standard for safe infusion of recirculated saline or blood in hemodialysis. A number of factors affect the bacteriologic and pyrogenic quality of recirculated saline and how individuals will physiologically respond to the final product. Attention to strict asepsis ...
Balogun T M TM Department of Haematology and Blood Transfusion, Lagos State University Teaching Hospital, P.M.B 21105 Ikeja, Lagos, - - 2014
This study was undertaken to determine the prevalence of hepatitis C virus antibodies (anti- HCV) among transfused patients with haematological disorders. and correlate this with the units of blood or blood products received This was a cross sectional study. Patients with haematological disorders who had received two or more units ...
Stonemetz Jerry L JL Department of Anesthesiology/Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, - - 2014
Blood utilization has become an important outcome measure for surgical patients because of the recognized risks and costs associated with transfusion. However, comparisons of blood utilization between providers or institutions are difficult, because there is no standard method for risk adjustment when assessing surgical blood requirements. We examined whether accepted ...
Aramaki Osamu O Department of Digestive Surgery, Nihon University School of Medicine, 30-1 Ohyaguchikami-machi, Itabashi-ku, Tokyo, 173-8610, - - 2014
The correlation between blood loss and the risk of postoperative complications was unclear in patients undergoing resection of hepatocellular carcinoma (HCC). We studied 539 patients who had resection of HCC. Postoperative complications were recorded according to the modified Clavien-Dindo classification. Variables were compared between patients with grade III to V ...
Appassakij Hatsadee H Department of Pathology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, - - 2014
Asymptomatic Chikungunya fever (CHIKF)-viremic blood donors could be a potential threat of spreading the disease unwittingly through contaminated blood transfusions. The relatively low prevalence of Chikungunya virus antibodies in the population and the records of more than 9000 suspected CHIKF cases raised concern about the potential transfusion-associated CHIKF during the ...
Holowaychuk Marie K MK Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, - - 2014
Objective-To determine whether the number, volume, or age of transfused packed RBC units; volume of other blood products; or pretransfusion PCV was a risk factor for transfusion-associated complications or nonsurvival in dogs. Design-Retrospective case series. Animals-211 client-owned dogs receiving stored packed RBC transfusions. Procedures-Information collected or calculated from the medical ...
Demirtas Sinan S Department of Cardiovascular Surgery, Medical School of Dicle University, Diyarbakir, - - 2014
ObjectiveThe aim of the present study is to evaluate whether blood count parameters differ according to the stages of Fontaine's classification and to investigate the relationship between hemogram parameters and the severity of the disease.MethodEighty-two peripheral arterial disease patients were examined prospectively. Patients were classified according to the Fontaine classification ...
Figuero Elena E Oral Research Laboratory, Faculty of Odontology, University Complutense, Madrid, - - 2014
Background: The aim of this investigation was to quantify periodontal pathogens (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Campylobacter rectus and Tannerella forsythia) in vascular, blood and subgingival samples. As secondary objective, two molecular bacterial identification methods [nested-polimerase chain reaction (PCR) and quantitative PCR (qPCR)] were compared. Methods: Seventy consecutive patients provided a ...
Cywinski Jacek B JB From the Departments of *General Anesthesiology and Transplant Center, †Quantitative Health Sciences, and ‡Hepato-pancreato-biliary and Transplant Surgery, Cleveland Clinic, Cleveland, - - 2014
Predicting blood product transfusion requirements during orthotopic liver transplantation (OLT) remains difficult. Our primary aim in this study was to determine which patient variables best predict recipient risk for large blood transfusion requirements during OLT. The secondary aim was to determine whether the amount of blood products transfused during OLT ...
Klatte Tobias T Department of Urology, Medical University of Vienna, Vienna General Hospital, Vienna, - - 2014
ABO blood type is an inherited characteristic that has been associated with the prognosis of several malignancies, but there is little evidence in urothelial carcinoma of the bladder (UCB). The purpose of this study was to evaluate the effect of ABO blood type on mortality in patients with UCB treated ...
Ely Craig R CR Alaska Science Center, U.S. Geological Survey, 4210 University Drive, Anchorage, AK, 99508, USA, - - 2014
Tundra swans (Cygnus columbianus) like many waterfowl species are susceptible to lead (Pb) poisoning, and Pb-induced mortality has been reported from many areas of their wintering range. Little is known however about Pb levels throughout the annual cycle of tundra swans, especially during summer when birds are on remote northern ...
Lu Jun J Intensive care unit, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, 155 Hanzhong Road, Nanjing 210029, Jiangsu Province, - - 2014
Severe acute pancreatitis is a life-threatening disease. Patients with peripancreatic necrotic infection often require surgical removal of necrotic infected tissue and a wide debridement will cause blood loss and worsen the condition. To assess whether treatment with NovoSeven, a recombinant activated FVII (rFVIIa), could improve coagulation function and therefore reduce ...
Rogers Natasha M NM Vascular Medicine Institute; Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA - - 2014
Cardiovascular homeostasis and health is maintained through the balanced interactions of cardiac generated blood flow and cross-talk between the cellular components that comprise blood vessels. Central to this cross-talk is endothelial generated nitric oxide (NO) that stimulates relaxation of the contractile vascular smooth muscle (VSMC) layer of blood vessels. In ...
Monneret Guillaume G Hospices Civils de Lyon, Immunology Laboratory, Hôpital E, Herriot, 5 place d'Arsonval, 69437, Lyon, cedex 03, France. - - 2014
The best marker for the monitoring of immune alterations in critically ill patients (sepsis, trauma, pancreatitis, surgery, burns) so far remains decreased HLA-DR expression on monocytes measured by flow cytometry as it regularly provides valuable information in terms of mortality prediction or evaluation of risk for secondary infections. As shown ...
Mafirakureva Nyashadzaishe N Unit of Pharmaco-Epidemiology & Pharmaco-Economics (PE2), Department of Pharmacy, University of Groningen, Groningen, The Netherlands National Blood Service Zimbabwe, Harare, - - 2014
Haemovigilance hinges on a systematically structured reporting system, which unfortunately does not always exist in resource-limited settings. We determined the incidence and pattern of transfusion-related adverse events reported to the National Blood Service Zimbabwe. A retrospective review of the transfusion-event records of the National Blood Service Zimbabwe was conducted covering ...
Chahine Lama M - - 2014
There is a pressing need for biomarkers to diagnose Parkinson's disease (PD), assess disease severity, and prognosticate course. Various types of biologic specimens are potential candidates for identifying biomarkers - defined here as surrogate indicators of physiological or pathophysiological states - but blood has the advantage of being minimally invasive ...
Jones Allison R AR RICH Heart Program, University of Kentucky College of Nursing (Dr Frazier), University of Kentucky College of Nursing (Ms Jones), - - 2014
Hemorrhage is a preventable cause of death among patients with trauma, and management often includes transfusion, either whole blood or a combination of blood components (packed red blood cells, platelets, fresh frozen plasma). We used the 2009 National Trauma Data Bank data set to evaluate the relationship between transfusion type ...
Goodall E E Operating Department, Glasgow Caledonian University. - - 2014
Transfusion associated circulatory overload (TACO) is a serious but under-recognised complication of blood transfusion. While the exact incidence rate is unknown the associated morbidity and mortality make this a transfusion reaction worthy of attention. This article provides details of a critical incident involving TACO followed by a literature review and ...
Danninger Thomas T 0000-0002-0933-5312 Department of Anesthesiology, Hospital for Special Surgery, Weill Medical College of Cornell University, 535 East 70th Street, New York, NY 10021, - - 2014
Background. Various studies have raised concern of worse outcomes in patients receiving blood transfusions perioperatively compared to those who do not. In this study we attempted to determine the proportion of perioperative complications in the orthopedic population attributable to the use of a blood transfusion. Methods. Data from 400 hospitals ...
Eboumbou Moukoko Carole Else CE Department of Biological Sciences, Faculty of medicine and pharmaceutical sciences, University of Douala, BP 2701 Douala, Cameroon. - - 2014
Transfusion-transmissible infections (TTIs) pose a major health risk in Cameroon given the high prevalence of such pathogens and increased demands for blood donations in the local communities. This study aims at establishing the prevalence of commonly encountered TTIs among blood donors and transfusion-related complications among recipients in an urban center ...
Urbanova Barbora B Department of Neurology, 2nd Faculty of Medicine, Motol University Hospital, Charles University , Prague , Czech - - 2014
There has been a growing interest in vascular impairment associated with Alzheimer's disease (AD). This interest was stimulated by the findings of higher incidence of vascular risk factors in AD. Signs of vascular impairment were investigated notably in the field of imaging methods. Our aim was to explore ultrasonographic studies ...
Olszewski Adam - - 2014
Minimisation of blood transmitted diseases is a basic element of all blood transfusion strategies. Civilian health service standards used in peacetime may be difficult to implement in a battlefield. The risk of blood-borne diseases depends on the applied donor qualification procedures and the epidemiological situation in the areas of military ...
Damiens David D Université catholique de Louvain, Earth and Life Institute, Biodiversity Research Centre, Louvain-la-Neuve, Belgium; Insect Pest Control Laboratory, International Atomic Energy Agency, Vienna, - - 2014
When accidentally introduced in a new location, a species does not necessarily readily become invasive, but it usually needs several years to adapt to its new environment. In 2009, a national mosquito survey (MODIRISK) reported the introduction and possible establishment of an invasive mosquito species, Aedes j. japonicus, in Belgium. ...
Cheng Lesley L Department of Biochemistry and Molecular Biology, The University of Melbourne, Melbourne, Australia ; Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, - - 2014
microRNA (miRNA) are small non-coding RNA species that are transcriptionally processed in the host cell and released extracellularly into the bloodstream. Normally involved in post-transcriptional gene silencing, the deregulation of miRNA has been shown to influence pathogenesis of a number of diseases. Next-generation deep sequencing (NGS) has provided the ability ...
Sarkari Bahador B Basic Sciences in Infectious Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. - - 2014
Toxoplasma gondii is a protozoan parasite which can be transmitted to human through a variety of routes including blood transfusion. This cross sectional study aimed to evaluate the seroprevalence of Toxoplasma infection and related epidemiological features among healthy blood donors. A total of 1,480 healthy blood donors from five blood ...
Santhanam Anand A Department of Radiation Oncology, University of California, Los - - 2014
The aim of this paper is to enable a simulation tool for cardiovascular blood flow in order to better understand normal and hemorrhage conditions. A second order partial differential model for cardiovascular blood flow is employed. The individual components of the model is represented as an RLC circuit representation. Injury ...
Vivekanantham Sayinthen S Faculty of Medicine, Imperial College London, London, - - 2014
A 55-year-old woman with a background of vascular disease presented with signs of bilateral limb ischaemia. Following elective axillobifemoral bypass and hospital discharge, accidental axillary trauma causing a chest wall haematoma, the patient underwent an emergency graft repair. Postextubation, she reported with absent sensation in her legs. Spinal cord infarction ...
Brick Thomas T Paediatric Intensive Care Unit, Great Ormond Street Hospital NHS Foundation Trust, Great Ormond Street, London WC1N 3JH, UK. - - 2014
Severe anemia contributes significantly to child mortality in sub-Saharan Africa. Blood transfusion is used in emergencies but carries risks. In BMC Medicine, Olupot-Olupot and colleagues report the findings of a phase II trial in children with severe anemia in Eastern Uganda. They provide important early safety and efficacy data supporting ...
Spada Eva E Veterinary Transfusion Unit (REV), Department of Health, Animal Science and Food Safety (VESPA), University of Milan, Via G. Celoria 10, 20133 Milan, - - 2014
Data from potential feline blood donors presented at two university blood banks in Italy were recorded. Blood typing was performed using an immunochromatographic method. Over the three years of the study 357 cats representing 15 breeds, 45.3% female and 54.7% male, with a mean age of 3.8 years were evaluated. ...
Szalai Alexander J AJ Division of Clinical Immunology and Rheumatology, Department of Medicine, The University of Alabama at Birmingham, 1825 University Boulevard, SHEL 214, Birmingham, Al 35294-2182, - - 2014
Raised blood C-reactive protein (CRP) level is a predictor of cardiovascular events, but whether blood CRP is causal in the disease process is unknown. The latter would best be defined by pharmacological inhibition of the protein in the context of a randomized case-control study. However, no CRP specific drug is ...
Lawrence S M SM Department of Pediatrics, Section of Neonatal-Perinatal Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, - - 2014
Transfusion Associated Necrotizing Enterocolitis (TANEC) is defined as the onset of necrotizing enterocolitis (NEC) within 48 hours of receiving a blood transfusion in preterm neonates. We wanted to determine if hematocrit changes following blood transfusions were associated with disease development. This is a case-control analysis of inborn neonates ≤32 weeks' ...
Schutte Hermien Janneke HJ Section of Geriatric Medicine, Department of Medicine, Academic Medical Center, Amsterdam, The - - 2014
Recent studies have shown that an increased bleeding tendency can be caused by Selective Serotonin Reuptake Inhibitors (SSRI) use. We aimed to investigate the occurrence and risk of blood transfusion in SSRI users compared to non-SSRI users in a cohort of patients admitted for hip-surgery. We conducted a retrospective cohort ...
Chawes Bo L BL Copenhagen Prospective Studies on Asthma in Childhood, Health Sciences, University of Copenhagen, Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, - - 2014
Epidemiological studies have suggested an association between maternal vitamin D dietary intake during pregnancy and risk of asthma and allergy in the offspring. However, prospective clinical studies on vitamin D measured in cord blood and development of clinical end-points are sparse. To investigate the interdependence of cord blood 25-hydroxyvitamin D ...
Jones Caroline N CN The BioMEMS Resource Center, Department of Surgery, Massachusetts General Hospital; Harvard Medical School; Shriners Burns - - 2014
Neutrophils play an essential role in protection against infections and their numbers in the blood are frequently measured in the clinic. Higher neutrophil counts in the blood are usually an indicator of ongoing infections, while low neutrophil counts are a warning sign for higher risks for infections. To accomplish their ...
Wang Jie J Department of Cardiology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beixiange 5, Xicheng District, Beijing 100053, - - 2014
Aspirin plays a crucial physiological and pathophysiological role in cardiovascular diseases and cerebrovascular diseases by irreversibly inhibiting thromboxane A2. However, some patients may be "resistant" to its effect. The resistance has close association with adverse cardiovascular outcomes and increased mortality, so that resolving the problem of aspirin resistance (AR) is ...
de Ceglia Francesco Paolo - - 2014
The aim of this paper is to reconstruct the way in which early modem science questioned and indirectly influenced (while being in its turn influenced by) the conceptualization of the liquefaction of the blood of Saint Januarius, a phenomenon that has been taking place at regular intervals in Naples since ...
Kumar Naresh N National University Health System, Singapore, Singapore. Electronic address: - - 2014
Metastatic spine tumour surgery (MSTS) and metastatic musculoskeletal tumour surgery (MMTS) are associated with substantial blood loss. Allogeneic blood transfusion is the present method used to replenish this blood. Intraoperative cell salvage (IOCS) is a viable alternative, but is contraindicated in tumour surgery because of the risk of tumour dissemination. ...
Gálvez Jorge A JA Department of Anesthesiology & Critical Care, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, - - 2013
Children are a vulnerable population in the operating room, and are particularly at risk of complications from unanticipated hemorrhage. The decision to prepare blood products prior to surgery varies depending on the personal experience of the clinician caring for the patient. We present the first application of a data visualization ...
Zhao-Yu Chen C Department of Orthopedics, Third Hospital of Hebei Medical University, Shijiazhuang, 050051, People's Republic of - - 2013
The purpose of the study is to conduct a meta-analysis of randomized, controlled trials evaluating the efficacy and safety of intra-articular injection of tranexamic acid (TXA) for reducing blood loss and transfusion in patients undergoing total knee arthroplasty (TKA). A meta-analysis was conducted of RCTs published before March 2013, identified ...
David Mazer C C Department of Anesthesia, St Michael's Hospital, University of Toronto, Keenan Research Centre for Biomedical Science and Li Ka Shing Knowledge Institute of St. Michael's Hospital, 30 Bond Street, Toronto, Ontario M5B 1W8, Canada; Department of Physiology, University of Toronto, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada. Electronic address: - - 2013
Bleeding related to cardiac surgery is an important clinical problem. Perioperative anemia and transfusion of allogeneic blood products have both been associated with adverse outcome including mortality and major morbidity. Guidelines exist to help determine when the risks of anemia outweigh the risks of transfusion. Perioperative bleeding may be related ...
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