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Results 601 - 650 of 761
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Machovich R - - 1986
Copolymers of poly/vinyl alcohol-acrylic acid/ with various content of sulphate and carboxyl groups have been synthetized and tested for their in vitro effect on blood coagulation. The results indicate that the sulphated copolymers display an inhibitory effect but there is a requirement in the charged groups of about 20% in ...
Zammit M - - 1986
The influence on healing of three materials for closure of interstices in a macroporous Dacron arterial prosthesis were evaluated by 56-day implantation in the canine descending thoracic aorta. The materials studied were: the nondenatured fibrin deposited as a result of a 4-step preclot with autogeneic blood (n = 6), heat-coagulated ...
Velasco F - - 1986
In order to assess the role of the kallikrein-kinin (K-K) system in the pathogenesis of the adult respiratory distress syndrome (ARDS) we have prospectively determined coagulation contact phase, blood gas and hemodynamic parameters in patients with ARDS at 0, 36 and 72 h from diagnosis. Compared to normal values, significantly ...
Wolfe J M - - 1986
In a tilt aftereffect (TAE) paradigm, 2 min of adaptation produced an aftereffect that decayed almost completely within 4 min. Four minutes of adaptation produced a TAE that lasted more than 2 wk. Two modes of adaptation contribute to the TAE and account for other aftereffects: short-term fatigue, produced very ...
Challoner T - - 1986
A study has been made of a number of haematological and haemorheological factors following venesection therapy. Haematocrit was very effectively reduced by the venesection regimen and led to a fall in whole blood viscosity in spite of the microcytosis that was eventually induced in all the subjects. No clinically significant ...
Gerber H - - 1986
Methods used for estimating in vivo diffusion velocity of thyroglobulin (Tgb), the factors affecting hydrodynamic properties of thyroidal colloid and the effects of changing diffusion properties on follicular function are briefly reviewed. The principal methods, besides pure in vitro techniques, are autoradiography of thyroid sections after in vivo labelling of ...
Schoeffel D - - 1986
We investigated selected coagulation parameters in 13 patients who had undergone open heart surgery with extracorporeal circulation (ECC). During ECC factor XIIa increased considerably to 38%. This may lead to intravascular coagulation, which is however inhibited during ECC by the administered heparin. The C1-inhibitor activity decreased to 12% during ECC, ...
Gralnick H R - - 1986
1-D-Amino(8-D-arginine)-vasopressin (DDAVP) infusion in three patients with type IIa von Willebrand's disease (vWD) resulted in a normalization of the factor VIII coagulant, factor VIII-related antigen, and von Willebrand factor (vWF) (ristocetin cofactor) activities and the bleeding time. The normalization of these hemostatic parameters persisted for four hours. Over the same ...
Colver G B - - 1986
The treatment of vascular naevi with lasers is widely practised. The concept of specific vascular damage was an early ideal but it is much harder to attain than had been anticipated. The favourable results achieved by coagulation necrosis of the epidermis and upper dermis with the argon and CO2 lasers ...
Pizzola P A - - 1986
The interpretation of bloodstain patterns at crime scenes has received increased attention in recent years. Important to an understanding of this is knowledge of the fundamentals of blood droplet formation and impact dynamics. A review of the literature reveals that a considerable amount of work has been done with aqueous ...
Kuroiwa T - - 1986
The effect of Nd:YAG and CO2 laser beams on cerebral microvasculature was examined in experimental animals. Soft x-ray microangiography and histological examination of the brain after Nd:YAG laser exposure revealed broad avascular or oligovascular zones in the irradiated and the surrounding edematous tissue, in which the surviving vessels were narrowed ...
Mustafa K Y - - 1985
Blood coagulation and fibrinolysis were assessed in 55 cases of heat stroke who presented with or without bleeding tendencies during the Makkah pilgrimage of 1983. 17 patients were identified to have evidence of disseminated intravascular coagulation (DIC). Bleeders with DIC had a higher incidence of shock and a higher mortality ...
Hatton P D - - 1985
A high performance aircraft test pilot who presented with acalculous cholecystitis was found to have a calcified omental hematoma adjacent to the gallbladder. Omental hematomas have not previously been linked to flight in high performance aircraft. Current prevailing hypotheses regarding etiologies of omental hematomas include rapid blood flow shifts and ...
Kang Y G - - 1985
The blood coagulation system of 66 consecutive patients undergoing consecutive liver transplantations was monitored by thrombelastograph and analytic coagulation profile. A poor preoperative coagulation state, decrease in levels of coagulation factors, progressive fibrinolysis, and whole blood clot lysis were observed during the preanhepatic and anhepatic stages of surgery. A further ...
Niwa M - - 1985
Wakan-Yakus (traditional herbal drugs) such as Akyoh (Glutinum), Gaiyoh (Artemisiae folium), Sanshishi (Gardeniae fructus), Kizutsu (Aurantii fructus), and Taisoh (Zizyphi fructus) were studied in relation to their effects on blood coagulation-fibrinolysis. (1) All of the water extracts of the Wakan-Yakus prolonged aPTT and PT. The potency of the effectiveness on ...
Tauber R - - 1985
Until now the forceps used for biopsy of the bladder has required a second procedure to coagulate the bleeding resulting from tissue removal. A new biopsy forceps is described, which makes it possible to perform the biopsy and coagulation simultaneously, thus, eliminating the inconvenience of having to change instruments during ...
Hewson J R - - 1985
A retrospective review of 64 patients receiving more than 10 units of red cell concentrate plus crystalloid within 12 h revealed two consecutive patterns of elevation of the partial thromboplastin time (PTT). The PTT at 3 to 4 h (PTT3-4) correlated with the number of liters of crystalloid (LC) infused ...
Schrems W - - 1985
The therapeutic effect of topically applied prostaglandin inhibitors on the laser-induced disruption of the blood-aqueous barrier was investigated in six series of five rabbits each. One series was not coagulated and served as baseline, and in a reference group laser coagulation was performed without pretreatment with a prostaglandin inhibitor. In ...
Ariga T - - 1985
FPA disappeared from the circulating blood along a double-exponential decay curve consisting of an initial phase (t 1/2 = 1.8 min) and a late phase (t 1/2 = 34.7 min). The rapid decrease in blood FPA was due to the large extravascular space, the size of which was estimated to ...
Levin J - - 1985
The Limulus Test for bacterial endotoxins was developed as the result of investigations of the effects of Gram-negative bacteria on blood coagulation in the horseshoe crab Limulus polyphemus. Analysis of the factors required for blood coagulation (all of which are contained within Limulus amebocytes) has revealed marked similarities between blood ...
Zondag A C - - 1985
Differences in the coagulation patterns between humans and dogs and the lack of reagents in the veterinary field to control haemostasis require a modification of existing screening techniques. The adaptations which were applied and which are described in this paper consist of greater dilutions of the samples. Two modified screening ...
De Wit C A - - 1985
Levels of blood coagulation factors were measured monthly in hedgehogs kept at 20 degrees C under a natural-light schedule for 1 yr using prothrombin time and the P & P method. Hedgehogs display a circannual cycle of blood coagulation factors in the absence of temperature cues, with high levels corresponding ...
Kaibara M - - 1985
In order to attempt in vitro evaluation of antithrombogenecity for materials of artificial blood vessel tube, a new type of rheometer was developed. The rheometer originally consists of a cylindrical tube suspended from a torsion wire and filled with blood. The tube is excited in torsional oscillation and subsequent damped ...
Dahlman T - - 1985
Blood coagulation and fibrinolysis variables have been studied in the normal puerperium in order to facilitate the decision to discontinue thrombosis prophylaxis after delivery. 16 women were followed longitudinally from the 1st to the 6th week post partum. Factor VIII activity and related antigen, fibrinogen, fibrinopeptide A, antithrombin III, plasminogen, ...
Lenihan D J - - 1985
Platelet activating factor (PAF) and 1-O-alkyl-linked choline-containing phosphoglycerides have been identified in the blood of the lizard, Anolis carolinensis. The level of PAF in the blood of chronically stressed lizards is 250% higher than in that of controls; the blood contains sufficient 1-O-alkyl-linked choline-containing phosphoglycerides to support the synthesis of ...
van Vliet K J - - 1985
The normal blood coagulation in Cyprinus carpio and Oreochromis mossambicus was investigated by thrombelastography and standard thrombelastographs were obtained for each species. The effect of stress on blood coagulation was thereafter determined. The thrombelastograms indicated hypercoagulability under stress conditions. A prominent observation is the differences in the elasticity of the ...
Cederholm-Williams S A - - 1984
Examination of coagulation factors in menstrual fluid collected from women with normal menstrual blood less (less than 80 ml) showed the absence of thrombin generating enzymes. Factor X, pro-thrombin and free thrombin were absent from menstrual fluid. No difference was found between days 1 and 2 of menstruation. Thus activation ...
Lartigue-Mattei C - - 1984
The blood and plasma kinetics of intravenously administered 3H-labelled PAF-acether were determined in seven rabbits. PAF-acether was rapidly distributed and slowly eliminated. Individual variations were very small. The main route of metabolism involves deacetylation of the PAF-acether into lyso-PAF-acether, leading to an equilibrium between the two molecules (10%/90%). This equilibrium, ...
Jackson R E - - 1984
Regional cerebral cortical blood flow (rCCBF) in 15 large dogs was determined using the double thermistor dilution method during standard closed-chest massage (CCM), CCM with an epinephrine infusion at 30 micrograms/kg/min (CCM + Epi), and open-chest cardiac massage (OCCM). As a percentage of prearrest flow values, the rCCBF was 9.8% ...
Bennett J S - - 1984
The hemostatic mechanism has evolved to provide efficient protection from traumatic blood loss and yet maintain the blood in a fluid state in the circulation as a whole. Recent advances in biochemistry have provided both detailed understanding of hemostasis and clinically useful coagulation assays to exploit this understanding. Clinicians now ...
Vignolo-Scalone W H - - 1984
Disseminated intravascular coagulation is often characterized by organ failure and bleeding. By use of light microscopy, previous studies have shown extensive fibrin deposition in vessels. However, quantification of fibrin deposition using ultrastructural methods has not been reported. In this study dogs were infused with thrombin, and disseminated intravascular coagulation developed. ...
Chohan I S - - 1984
Yoga is known to induce beneficial effects on physiological, biochemical and mental functions in man. Its effects on blood coagulation are not known. A study was conducted in seven previously untrained male adults who underwent a combination of yogic exercises, daily for one hour, over a period of four months. ...
Prandota J - - 1984
In rabbits intravenous injection of subtoxic doses of E. coli endotoxin serotype 02:K1 (10 micrograms/kg), resulted in the activation of intrinsic and extrinsic pathways of blood coagulation and, in some animals, simultaneous fall of the fibrinolytic activity which was manifested by hypercoagulability and intravascular coagulation already at the initial stage ...
Inkster M - - 1984
Antithrombin III (AT-III) is the major inhibitor of thrombin, Factor Xa, and other coagulation enzymes. Congenital and acquired deficiencies of AT-III are thought to contribute to thrombosis and disseminated intravascular coagulation. Because a recent report suggested reduced AT III in stored blood, we evaluated blood bank storage effects. Serial samples ...
Ferencz C - - 1984
In a population-based study on congenital cardiovascular malformations (CCVM), the occurrence of heritable coagulopathies among case parents and not among controls raised the possibility of an etiologic association of CCVM with blood disorders. The literature was searched for evidence that such an association could be biologically plausible. Reported embryologic and ...
Schultz R E - - 1983
Extravasation of glycine irrigant during percutaneous ultrasonic lithotripsy has caused a transurethral resection syndrome consisting of hypertension, confusion and hyponatremia. With a rabbit model this complication is recreated with the intraperitoneal instillation of 1.5 per cent glycine solution tagged with 14carbon-glycine. Significant quantitative absorption of glycine into blood and other ...
Köstering H - - 1983
Blood coagulation studies were performed on 60 Hanover domestic pigs ready for slaughter and a total of 84 Goettingen minipigs. A tendency to hypercoagulability was found in these pigs, expressed in a shortened PTT, r- and k-time in the thromboelastogram and a slightly reduced plasminogen and plasmin level. Many values ...
Nilsson L - - 1983
Whole blood and plasma drawn into plastic bags containing citrate-phosphate-dextrose (CPD) and stored at 4 degrees C for various periods were studied for variations of coagulation factor and fibrinolytic activity. The blood was collected and processed in the conventional way. The most labile component, factor VIII coagulant activity, decreased to ...
Arai H - - 1983
Dynamic fluctuations of biological activities and antigen amounts of antithrombin III (AT-III) in acute cerebrovascular diseases were analyzed and evaluated. (1) AT-III levels assayed by both biological and immunological methods showed a gradual decrease with increasing age, and levels in patients with cerebral thrombosis were lower than those in patients ...
d'Onofrio G - - 1983
Using an automated cytochemical analyzer used for routine differential counts, we have been able to demonstrate acquired myeloperoxidase deficiency in 102 patients at our institution. Clinical and laboratory data on these patients showed a high incidence of diabetes mellitus (25.5%) and thrombotic diseases (24.5%), as well as a strikingly constant ...
Nemerson Y - - 1983
Factor VII, a single-chain zymogen, has sufficient proteolytic activity to initiate blood coagulation. The reason that coagulation does not occur continuously is that the zymogen like its 2-chain derivative enzyme, factor VIIa, absolutely requires tissue factor. The latter, a lipid-dependent glycoprotein, is not normally present in the blood. Upon tissue ...
Chernukh A M - - 1983
It is important to emphasize that the biochemical systems participating in humoral hemodynamic regulation may function at any level of the circulatory homeostasis: in the blood as a biological fluid constantly circulating along the vessels, at the microcirculatory bed where the exchange with tissues is realized, on the tonic activity ...
Marcel G A - - 1983
For Virchow vessel wall, coagulability and flow were the three eventual culprits of thrombogenesis. Pharmacological progress in the three fields has not been parallel. Strangely enough they have found possible therapy in the order of their description: first the vessel wall with vasodilators. Then 'coagulability' with anticoagulants, thrombolytics, antiaggregants. It ...
Carlebjörk G - - 1983
Blood collected into different anticoagulants was stored in small tubes at +4 degrees C for up to 26 h. Seven blood coagulation analyses were performed under standardized conditions. High yield and stability of factor VIII:C were found for ACD and CPD-adenine. No changes could be found in the other six ...
Srivastava A K - - 1983
Exposure of a freshwater teleost, Heteropneustes fossilis, to a concentration of 14 . 625 mg per 1 (0.9 of 96 h LC50) fenthion induced muscle and hepatic glycogenolysis with concomitant hyperglycaemia at 2, 6, 12 and 48 h after treatment. The pesticide evoked an initial fall (at 2 and 6 ...
Sohmer P R - - 1982
Extension of the time within which whole blood may be separated into components offers logistic advantages for the operation of remote mobile drawing teams. We evaluated the effect of an 8-hour hold of whole blood at room temperature before preparation of components. Plasma coagulation activity and opsonic factor content were ...
Hellings J A - - 1982
To evaluate the extent of denaturation of factor VIII-coagulant activity (VIII: C) during production of factor VIII concentrates, the factor VIII-coagulant antigen (VIII: CAg)/VIII: C ratio was measured in plasma, cryoprecipitate and cryosupernatant from fresh and stored blood. This ratio was close to unity for both cryoprecipitate and other concentrates, ...
Carney L G - - 1982
The blinking patterns of 20 normal subjects were examined under controlled experimental conditions. While the mean blink rate was 12.55 blinks/min, there were marked variations between individuals. As well, each subject displayed a characteristic pattern of blinking, mixing inter-blink periods of shorter and longer durations in a regular fashion.
Hondow J A - - 1982
The complete coagulation profile of citrate phosphate dextrose (CPD) stored blood has been studied during 21 days storage at 4 degrees C. Ten donations were studied at zero, one, seven, 14 and 21 days. One donation contained small clots and was studied separately. Activities of factors I, II, IX, XII ...
Teitel J M - - 1982
We have evaluated the efficacy of utilizing radioimmunoassays (RIAs) for prothrombin activation fragments (F2/F1 + 2) and for thrombin--antithrombin complex (TAT) in purified systems and in whole blood. During venipuncture, appropriate anticoagulants were employed in order to prevent the generation of thrombin and factor Xa. The RIAs were shown to ...
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