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Mohite Prashant N PN Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, London, - - 2014
The Synergy® CircuLite® micropump is a novel partial-support miniature left ventricular assist device that propels 2-3 l/min blood from the left atrium into the right subclavian artery. The ability of currently available investigative modalities to confirm Synergy pump malfunction is limited. The Synergy speed fluctuates periodically (at 10-s intervals) from ...
Chan Chris H H CH Institute of Life Science, College of Medicine, Swansea University, Swansea, Wales, - - 2014
Implantable ventricular assist devices (VADs) have proven efficient in advanced heart failure patients as a bridge-to-transplant or destination therapy. However, VAD usage often leads to infection, bleeding, and thrombosis, side effects attributable to the damage to blood cells and plasma proteins. Measuring hemolysis alone does not provide sufficient information to ...
Mayaud Cyril C University of Graz, Institute of Earth Sciences, NAWI Graz, Heinrichstraße 26, A-8010 Graz, - - 2014
A new MODFLOW package (Nonlinear Flow Process; NLFP) simulating nonlinear flow following the Forchheimer equation was developed and implemented in MODLFOW-2005. The method is based on an iterative modification of the conductance calculated and used by MODFLOW to obtain an effective Forchheimer conductance. The package is compatible with the different ...
Karolyi Florian F Department of Integrative Zoology, University of Vienna, Faculty of Life Science, Althanstrasse 14, 1090 Vienna, Austria. Electronic address: - - 2014
Female Pangoniinae in the tabanid fly genus Philoliche can display remarkably elongated proboscis lengths, which are adapted for both blood- and nectar-feeding. Apart from their role as blood-sucking pests, they represent important pollinators of the South African flora. This study examines the morphology of the feeding apparatus of two species ...
Bork Toralf T Codman Neuro Sciences Sàrl, Rue Girardet 29, 2400, Le Locle, - - 2014
The MedStream Programmable Infusion Pump, an intrathecal pump indicated for the treatment of chronic intractable pain and severe spasticity (CE-mark) or severe spasticity (US), has a highly accurate medication delivery (within 10 % of the programmed flow rate) and is certified for use in 3-Tesla magnetic resonance imaging systems (conditional). Performance ...
Biscotti Mauer M *Department of General Surgery, Columbia University Medical Center, New York, NY ¶Department of Cardiothoracic Surgery, Columbia University Medical Center, New York, - - 2014
Extracorporeal membrane oxygenation (ECMO) is used in the management of refractory cardiopulmonary failure. With improvements in technology, patients can be transferred between hospitals, ambulate, and be supported for extended periods of time while on ECMO. The SYNERGY CircuLite ™ micro-pump is a blood pump that has been used as a ...
Buciuc R R Radiology, Maimonides Medical Center, New York, NY, - - 2014
Currently endovascular navigation is performed by using fluoroscopy. This modality has some disadvantages such as, radiation, use of contrast and lack of visualization of brain parenchyma in "real time". The purpose of this study was to test the feasibility of navigating endovascular instruments on a flow model and in a ...
Ha Hojin H Department of Mechanical Engineering, Pohang University of Science and Technology, San 31, Hyoja-dong, Pohang 790-784, Republic of - - 2014
The existence of swirling flow phenomena is frequently observed in arterial vessels, but information on the fluid-dynamic roles of swirling flow is still lacking. In this study, the effects of pulsatile swirling inlet flows with various swirling intensities on the flow field in a stenosis model are experimentally investigated using ...
Gramigna V V a Bioengineering Unit, Magna Graecia University , Catanzaro , - - 2014
In the modern era, stroke remains a main cause of morbidity after cardiac surgery despite continuing improvements in the cardiopulmonary bypass (CPB) techniques. The aim of the current work was to numerically investigate the blood flow in aorta and epiaortic vessels during standard and pulsed CPB, obtained with the intra-aortic ...
Blum Martin M University of Hohenheim, Institute of Zoology, D-70593 Stuttgart, Germany. Electronic address: - - 2014
Asymmetric development of the vertebrate embryo has fascinated embryologists for over a century. Much has been learned since the asymmetric Nodal signaling cascade in the left lateral plate mesoderm was detected, and began to be unraveled over the past decade or two. When and how symmetry is initially broken, however, ...
Tran Minh-Ha MH Department of Pathology and Laboratory Medicine, UC Irvine School of Medicine, Irvine, - - 2014
Cardiothoracic surgery places significant demands on blood bank resources. Measures aimed at reducing intraoperative hemodilution were initiated as part of a blood conservation program. We initiated a series of measures aimed at reducing hemodilution volume: 1) reduction of intravenous fluid (IVF) volume, 2) reduction of circuit size, and 3) use ...
Le Noel Anne A Departments of aAnaesthesiology and Critical Care bEmergency Medicine and Surgery, Pitié Salpêtrière University Hospital cFaculty of Medicine, Pierre et Marie Curie University dVygon, Paris, - - 2014
Despite now being rarely used in the prehospital and emergency department arena because of their excessive length and low inner diameter, narrow-bore central venous catheters (CVC) are sometime used to perform fluid resuscitation using a rapid infusion pump to enhance delivered flow. In this bench study, we tested the hypothesis ...
Kanungo Lizy L Biosensor Laboratory, Department of Chemistry, BITS, Pilani-K. K. Birla Goa Campus, Goa, 403726, India, - - 2014
Label-free detection technique based on impedance was investigated for aflatoxin M1 (AFM1) and aflatoxin M2 (AFM2) analysis in milk products. The impedance change resulting from antigen-antibody interaction was studied using a two-electrode setup made up of silver (Ag) wire. Processed milk such as drinking yogurt and flavored milk samples were ...
Rossi Tommaso T *Eye Hospital of Rome, University of Cagliari, Cagliari, Italy, FAculty of Engineering, DICAT Department, Bietti Foundation IRCCS, Rome, Italy, Optikon 2000 Inc, Rome, Italy; †University of Cagliari, DICAAR; ‡Optikon 2000 Inc; and §Fondazione G.B. Bietti, - - 2014
To assess the efficacy of novel vitreous cutter blades compared with the regular guillotine by means of particle image velocimetry. Tested blades included a regular blade (RB) and newer designs where a circular (hole blade [HB]) or a slit aperture (slit blade [SB]) had been opened proximal to the cutting ...
McMillan Lindsay A LA Water Sciences Group, School of Geography, Earth & Environmental Sciences, University of Birmingham, Birmingham B15 2TT, UK. Electronic address: - - 2014
Pumped groundwater sampling evaluations often assume that horizontal head gradients predominate and the sample comprises an average of water quality variation over the well screen interval weighted towards contributing zones of higher hydraulic conductivity (a permeability-weighted sample). However, the pumping rate used during sampling may not always be sufficient to ...
Pirbodaghi Tohid T Group for Cardiovascular Engineering, ARTORG Center for Biomedical Engineering Research, University of Bern, Bern, Switzerland; Thoratec Corporation, Burlington, MA, - - 2014
We investigated the power consumption of a HeartMate III rotary blood pump based on in vitro experiments performed in a cardiovascular simulator. To create artificial-pulse mode, we modulated the pump speed by decreasing the mean speed by 2000 rpm for 200 ms and then increasing speed by 4000 rpm (mean speeds plus 2000 rpm) ...
Wang Dongfang D Cardiothoracic Surgery Division, Department of Surgery, University of Kentucky, Lexington, Ky. Electronic address: - - 2014
The Avalon Elite (Macquet, Rastatt, Germany) double-lumen cannula can provide effective cavopulmonary assistance in a Fontan (total cavopulmonary connection) sheep model, but it requires strict alignment. The objective was to fabricate and test a newly designed paired umbrella double-lumen cannula without alignment requirement. The paired membrane umbrellas were designed on ...
Bell James - - 2014
We evaluated the Hospira Plum A+ (HB) hyperbaric infusion pump under monoplace and multiplace hyperbaric conditions to test pump flow accuracy. Pump flow accuracy was tested in monoplace and multiplace hyperbaric chambers at different rates, fluid viscosities, pressures and volumes. Output was recorded from the pump (programmed) and from graduated ...
Yang Feng - - 2014
The addition of an intra-aortic balloon pump (IABP) during peripheral venoarterial extracorporeal membrane oxygenation (VA ECMO) support has been shown to improve coronary bypass graft flows and cardiac function in refractory cardiogenic shock after cardiac surgery. The purpose of this study was to evaluate the impact of additional IABP support ...
Suzuki Kenji K Department of Cardiovascular Surgery, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, - - 2014
The algorithm for the physiological control provided by left ventricular assist devices (LVADs) has been controversial. In particular, little is known about the physiological control algorithm (such as for achieving physiological circadian rhythms) in continuous-flow LVADs. To investigate the existence of circadian variation, we retrospectively evaluated the LVAD flow-correlated motor ...
Rezaienia Mohammad Amin MA School of Engineering and Materials Science, Queen Mary University of London, London, - - 2014
This study investigates the novel approach of placing a ventricular assist pump in the descending aorta in series configuration with the heart and compares it with the two traditional approaches of left-ventricle-to-ascending-aorta (LV-AA) and left-ventricle-to-descending-aorta (LV-DA) placement in parallel with the heart. Experiments were conducted by using the in-house simulator ...
Mohseni Masood M Department of Anesthesiology, Rasoul Akram Medical Center, Iran University of Medical Sciences, Tehran, - - 2014
One of the frequent applications of elastomeric infusion pumps is postoperative pain management. In daily practice, the disposable pumps get refilled with modified medication combinations in the successive days; although, the accuracy of infusion rates is unknown to clinicians. Our aim was to evaluate the effect of repeated filling on ...
Sonntag Simon J SJ Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, RWTH Aachen University and University Hospital Aachen, Aachen - - - 2014
Purpose: For blood pumps with long term indication, blood stagnation can result in excessive thromboembolic risks for patients. This study numerically investigates the washout performance of the left pump chamber of a pulsatile total artificial heart (TAH) as well as the sensitivity of the rotational orientation of the inlet bileaflet ...
Yang Cheng-Zhang CZ Laboratory of Analytical Biochemistry and Bioseparation, Key State Laboratory of Microbial Metabolism, School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, - - 2014
Uneven flow in free-flow electrophoresis (FFE) with a gravity-induced fraction collector caused by air-bubbles in outlets and/or imbalance of the surface tension of collecting tubes would result in a poor separation. To solve these issues, this work describes a novel collector for FFE. The collector is composed of a self-balance ...
Teman Nicholas R NR University of Michigan, Department of Surgery, ECLS Laboratory 5153, B560 MSRB II, 1150 W. Medical Center Drive, Ann Arbor, MI 48109 University of Michigan, Department of Cardiac Surgery, Cardiovascular Center, 1500 E. Medical Center Drive, Ann Arbor, MI 48109 MC3 Inc, 3526 W. Liberty, Ann Arbor, MI - - 2014
It has been suggested that pulsatile blood flow is superior to continuous flow in cardiopulmonary bypass (CPB). However, adoption of pulsatile flow (PF) technology has been limited due to practically and complexity of creating a consistent physiologic pulse. A pediatric pulsatile rotary ventricular pump (PRVP) was designed to address this ...
Pfluecke C C University of Technology Dresden, Heart Center Dresden, University Hospital, Dresden, - - 2014
The current goal of treatment after acute ischemic stroke is the increase of cerebral blood flow (CBF) in ischemic brain tissue. Intra-aortic balloon pump (IABP) counterpulsation in the setting of cardiogenic shock is able to reduce left ventricular afterload and increase coronary blood flow. The effects of an IABP on ...
Park M M Research and Education Institute, Sírio Libanês Hospital, São Paulo, - - 2014
Transmembrane pressure drop reflects the resistance of an artificial lung system to blood transit. Decreased resistance (low transmembrane pressure drop) enhances blood flow through the oxygenator, thereby, enhancing gas exchange efficiency. This study is part of a previous one where we observed the behaviour and the modulation of blood pressure ...
Kimura Sumito S Department of Pediatric Cardiology, Oregon Health and Science University, 3181 SW Sam Jackson Park Dr, L608, Portland, OR 97239-3098 USA. - - 2014
Objectives- The aim of this study was to assess the accuracy, feasibility, and reproducibility of determining stroke volume from a novel 3-dimensional (3D) color Doppler flow quantification method for mitral valve (MV) inflow and left ventricular outflow tract (LVOT) outflow at different stroke volumes when compared with the actual flow ...
Borges Alessandra B AB Department of Restorative Dentistry, Universidade Estadual Paulista, São José dos Campos, - - 2014
This study investigated the effect of a calcium lactate prerinse on sodium fluoride protection in an in vitro erosion-remineralization model simulating two different salivary flow rates. Enamel and dentin specimens were randomly assigned to 6 groups (n = 8), according to the combination between rinse treatments - deionized water (DIW), ...
Shahraki Zahra Hashemi ZH * Lecturer at Mechanical department (Biomechanics group) of Islamic Azad University of Najafabad † Assistant Professor at Mechanical department (Biomechanics group) of Sahand University of - - 2014
Hemolysis and Thrombus formation which are critical concerns in designing a long-term implantable ventricular assist device (VAD) have impeded the widespread use of VADs. In this study, thus, the 3D fluid domain of blood flow in a small bi-chamber positive displacement VAD (25cc) with a magnetically levitated moving pusher plate ...
Chopski Steven G SG BioCirc Research Laboratory, Department of Mechanical and Nuclear Engineering, School of Engineering, Virginia Commonwealth University, Richmond, VA, - - 2014
A mechanical blood pump specifically designed to increase pressure in the great veins would improve hemodynamic stability in adolescent and adult Fontan patients having dysfunctional cavopulmonary circulation. This study investigates the impact of axial-flow blood pumps on pressure, flow rate, and energy augmentation in the total cavopulmonary circulation (TCPC) using ...
Bottrell S S 1Perfusion Department, Royal Children's Hospital, Melbourne, Victoria, - - 2014
One challenge in providing extracorporeal circulation is to supply optimal flow while minimising adverse affects, such as haemolysis. To determine if the recent generation constrained vortex pumps with their inherent design improvements would lead to reduced red cell trauma, we undertook a study comparing three devices. Utilizing a simulated short-term ...
Li Zida Z Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong, China. - - 2014
We report a new method to display the minute fluctuations induced by syringe pumps on microfluidic flows by using a liquid-liquid system with an ultralow interfacial tension. We demonstrate that the stepper motor inside the pump is a source of fluctuations in microfluidic flows by comparing the frequencies of the ...
Liu Guangmao - - 2014
The properties of blood flow in the outflow cannula of an axial blood pump play a critical role in potential thrombus formation and vascular injury. In this study, an in vitro flow visualization technique using particle image velocimetry (PIV) was applied to investigate the flow characteristics in the outflow cannula ...
Kang Can - - 2014
Rotary blood pump (RBP) is a kind of crucial ventricular assist device (VAD) and its advantages have been evidenced and acknowledged in recent years. Among the factors that influence the operation performance and the durability of various rotary blood pumps, medium property and the flow features in pump's flow passages ...
Xu Ying Y School of Energy and Architecture, Harbin University of Commerce, Harbin 150028, - - 2014
The flow characteristics of raw sewage directly affect the technical and economic performance of sewage-source heat pump systems. The purpose of this research is to characterize the flow characteristics of sewage by experimental means. A sophisticated and flexible experimental apparatus was designed and constructed. Then the flow characteristics of the ...
Wenhua Qian Q Department of Computer Science and Engineering, School of Information Science and Engineering, Yunnan University, Kunming 650091, - - 2014
The paper presents an NP-video rendering system based on natural phenomena. It provides a simple nonphotorealistic video synthesis system in which user can obtain a flow-like stylization painting and infinite video scene. Firstly, based on anisotropic Kuwahara filtering in conjunction with line integral convolution, the phenomena video scene can be ...
Gaddum Nicholas R NR Division of Imaging Sciences and Biomedical Engineering, St. Thomas' Hospital, King's College London, London, - - 2013
The application of rotary left ventricular (LV) assist devices (LVADs) is expanding from bridge to transplant, to destination and bridge to recovery therapy. Conventional constant speed LVAD controllers do not regulate flow according to preload, and can cause over/underpumping, leading to harmful ventricular suction or pulmonary edema, respectively. We implemented ...
Hong Sungmin - - 2013
We developed a microfluidic flow-control system capable of dynamically generating various flow patterns on demand. The flow-control system is based on novel magnetoactive sponges embedded in microfluidic flow channels. Applying a non-uniform magnetic field compresses the magnetoactive sponge, significantly reducing porosity and hydraulic conductivity. Tuning the applied magnetic field can ...
Tuzun Egemen - - 2013
The effects of the continuous-flow output on renal and intestinal microcirculation have not been extensively studied. To address this, the Heartware HVAD pump loaded with continuous and intermittent reduced speed (IRS) modes was implanted in four sheep and then operated at low and high speeds to mimic partial and complete ...
Bakouri Mohsen A - - 2013
Clinically adequate implementation of physiological control of a rotary left ventricular assist device requires a sophisticated technique such as the recently proposed method based on the Frank-Starling mechanism. In this mechanism, the stroke volume of the heart increases in response to an increase in the volume of blood filling the ...
Cohn William E - - 2013
We evaluated the effects of steady state flow and perfusion on end-organ function in a long-term calf model. The animal received a continuous-flow total artificial heart (CFTAH) that we created from two axial-flow ventricular assist devices. Pump flow, blood pressure, and other pump parameters were monitored throughout the study, as ...
Wang Shigang - - 2013
The objective of this study was to evaluate the pump performance of the third-generation Medos diagonal pump, the Deltastream DP3, on hemodynamic profile and pulsatility in a simulated pediatric mechanical circulatory support (MCS) system. The experimental circuit consisted of a Medos Deltastream DP3 pump head and console (MEDOS Medizintechnik AG, ...
Leme Juliana - - 2013
A new model of centrifugal blood pump for temporary ventricular assist devices has been developed and evaluated. The design of the device is based on centrifugal pumping principles and the usage of ceramic bearings, resulting in a pump with reduced priming (35 ± 2 mL) that can be applied for up to 30 ...
Koochaki Mojtaba - - 2013
Considering small thoracic space, using implantable ventricular assist device requires reduction in a pump size. Among many available blood pumps, axial blood pumps have attracted greatly because of their small size. In this article, a new miniature axial blood pump has been designed and studied which can be easily implanted ...
Banthitkhunanon P - - 2013
To determine the effect of enamel and dentine thickness on laser Doppler blood-flow (LDF) signals recorded from dental pulp. Observations were made on 18 human premolars that had been extracted from young patients during orthodontic treatment. The apical 2/3 of the root was cut off and the remaining pulp removed. ...
da Silva Cibele - - 2013
The Spiral Pump (SP), a centrifugal blood pump for cardiopulmonary bypass (CPB), has been developed at the Dante Pazzanese Institute of Cardiology/Adib Jatene Foundation laboratories, with support from Sintegra Company (Pompeia, Brazil). The SP is a disposable pump with an internal rotor-a conically shaped fuse with double entrance threads. This ...
Geers A J - - 2013
Computational fluid dynamics (CFD) simulations can be employed to gain a better understanding of hemodynamics in cerebral aneurysms and improve diagnosis and treatment. However, introduction of CFD techniques into clinical practice would require faster simulation times. The aim of this study was to evaluate the use of computationally inexpensive steady ...
Lal Cerine - - 2013
Blood flow velocity and red blood cell concentration are of vital importance in assessing tissue microcirculation. Laser speckle contrast analysis is being considered as a promising tool in the qualitative assessment of flow velocity as well as scatterer concentration in different body fluids, though the quantification part still remains challenging. ...
Repa A - - 2013
Blood transfusions are required by the majority of extremely premature infants. Packed red blood cells (PRBCs) are usually applied via simple peripheral cannulas. In situations where no peripheral venous access is achievable, 27 Gauge (G) neonatal PICC lines - that are ideally exclusively dedicated to application of parenteral nutrition - ...
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