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Cahill Lindsay S LS Mouse Imaging Centre, The Hospital for Sick Children, Toronto, Ontario, - - 2014
Mice reproduce many features of human pregnancy and have been widely used to model disorders of pregnancy. However, it has not been known whether fetal mice reproduce the physiologic response to hypoxia known as brain sparing, where blood flow is redistributed to preserve oxygenation of the brain at the expense ...
Masoller N N BCNatal - Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Clínic and Hospital Sant Joan de Déu), IDIBAPS, University of Barcelona, and Centre for Biomedical Research on Rare Diseases (CIBER-ER), Barcelona, - - 2014
The aim of our study was to evaluate the association of CHD on head biometry and cerebrovascular blood flow dynamics at the time of diagnosis in the second trimester of pregnancy. 95 consecutive fetuses diagnosed with CHD. At the time of diagnosis of CHD, we assessed fetal biometry and brain ...
García-Esquinas Esther E Environmental and Cancer Epidemiology Unit, National Centre for Epidemiology, Carlos III Institute of Health (Instituto de Salud Carlos III-ISCIII), C/ Sinesio Delgado 6, 28029, Madrid, Spain, - - 2014
This study is part of the BioMadrid Project, a bio-monitoring study designed to assess pollutants in the environment surrounding children born in the Madrid region. Our aim in this report is to evaluate the association between prenatal lead exposure and fetal development using three biological samples (maternal and paternal blood ...
Choi Gyuyeon G College of Medicine, Soonchunhyang University, Seoul, Republic of - - 2014
Polybrominated diphenyl ethers (PBDEs) are of growing public health concern because of their potential toxicities which range from endocrine disruption to neurodevelopment. However, information on their exposure among sensitive human populations is limited. The objectives of this study were to determine the levels of major PBDEs in blood sera of ...
Noh Eun Ji EJ Department of Obstetrics and Gynecology, Chonnam National University Medical School, Gwangju, - - 2014
The purpose of our study was to investigate the effect of the mode of delivery on the oxidant and antioxidant system in umbilical cord blood. We performed gas analysis of umbilical venous blood and umbilical arterial blood immediately after delivery in 38 women; eighteen women had a vaginal delivery while ...
Katheria Anup C AC Department of Neonatology, Sharp Mary Birch Hospital for Women and Newborns, San Diego, CA. Electronic address: - - 2014
To determine whether umbilical cord milking (UCM) improves systemic blood flow and reduces neonatal morbidities compared with immediate cord clamping (ICC). Women admitted to a tertiary care center and delivering before 32 weeks' gestation were randomized to receive UCM or ICC. Three blinded serial echocardiograms were performed in the first ...
Camacho L E LE Department of Animal Sciences, North Dakota State University, Fargo, North Dakota, - - 2014
The objective was to examine the effect of maternal nutrient restriction followed by realimentation during midgestation on uterine blood flow (BF). On Day 30 of pregnancy, lactating, multiparous Simmental beef cows were assigned randomly to treatments: control (CON; 100% National Research Council; n = 6) and nutrient restriction (RES; 60% of CON; ...
Hasegawa Junichi J Department of Obstetrics and Gynecology, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan, - - 2014
To clarify whether maternal anemia could reduce placental volume in the early gestation. A prospective cross-sectional study was conducted. Consecutive women who visited at 11-13 + 6 weeks' gestation were enrolled. Subjects were divided into two groups by maternal hemoglobin concentration. Cases with maternal anemia were defined as a hemoglobin level less than ...
Su H H Department of Obstetrics and Gynecology Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, - - 2014
Objective:To perform a quantitative review of the evidence on the diagnostic value of inflammatory markers in maternal serum or umbilical cord blood for the diagnosis of early-onset neonatal sepsis (EONS).Study Design:We searched multiple databases for studies published through March 2013 that evaluated the diagnostic performance of procalcitonin (PCT), C-reactive protein ...
Khatib Nizar N The Ultrasound Division, Department of Obstetrics and Gynecology, Rambam Medical Center, Haifa, Israel. Electronic address: - - 2014
The brain sparing phenomenon in the fetus is a protective mechanism aimed at maintaining sufficient blood flow towards the brain during chronic or acute fetal stress, such as that caused by hypoxemia or utero-placental insufficiency. In this study we investigated whether the brain sparing effect can also be elicited by ...
Helbig Anne A Norwegian Resource Centre for Women's Health, Oslo University Hospital, Oslo, Norway ; Department of Obstetrics, Oslo University Hospital, Oslo, - - 2014
Antenatal maternal psychological distress may be associated with reduced placental circulation, which could lead to lower birthweight. Studies investigating this in humans show mixed results, which may be partially due to type, strength and timing of distress. In addition, the arterial vascular resistance measures often used as outcome measures do ...
Ssemaganda Aloysius A Uganda Virus Research Institute - International AIDS Vaccine Initiative, Entebbe, - - 2014
We have previously shown that in successful pregnancies increased arginase activity is a mechanism that contributes to the suppression of the maternal immune system. We identified the main type of arginase-expressing cells as a population of activated low-density granulocytes (LDGs) in peripheral blood mononuclear cells and in term placentae. In ...
Shaw C J CJ Imperial College London, , Hammersmith Campus, Du Cane Road, London W12 0HS, - - 2014
High-intensity focused ultrasound (HIFU) is a non-invasive technology, which can be used occlude blood vessels in the body. Both the theory underlying and practical process of blood vessel occlusion are still under development and relatively sparse in vivo experimental and therapeutic data exist. HIFU would however provide an alternative to ...
Hussein Ayad Ahmed AA Bone Marrow and Stem Cell Transplantation Program, King Hussein Cancer Center, Amman, - - 2014
Cord blood transplant is an accepted treatment for many malignant and non-malignant diseases. We sought to determine the feasibility of collecting cord blood in Jordan and the effect of maternal and fetal factors on the quality of the cord blood units. A total of 124 cord blood units were collected, ...
Olsen Richelle N RN Department of Reproductive Medicine, University of California, San Diego, CA, - - 2014
Objective. Abnormal umbilical artery Doppler (UAD) studies are associated with poor neonatal outcomes. We sought to determine if postnatal measures of systemic blood flow (SBF), as measured by functional echocardiography (fECHO), could identify which fetuses with abnormal UAD were at the highest risk of adverse outcomes. Study Design. This is ...
- - 2013
The aims were to assess the placental and fetal circulation during nifedipine tocolysis within the first 48 hours of therapy. Placental and fetal circulation was assessed in Doppler ultrasound examination prior to nifedipine administration and then after 24 and 48 hours. Maternal heart rate and PI in uterine arteries were ...
- - 2013
The aims were to investigate whether there are any changes in placental and fetal circulation during Atosiban tocolysis within the first 48 hours of therapy. Detailed Doppler evaluation of placental and fetal circulation was performed prior to Atosiban administration and thereafter at 24 and 48 hours. Maternal heart rate and ...
Mutlu Ilknur I * Department of Obstetrics and Gynaecology, Elazig Training and Research Hospital , Elazig , - - 2013
Objectives To evaluate the predictive value of uterine artery Doppler characteristics in predicting copper intrauterine device (IUD)-induced side effects such as dysmenorrhoea and menorrhagia, and worsening of dyspareunia. Methods One hundred and twenty regularly menstruating women were enrolled in the study. All underwent transvaginal uterine artery Doppler analysis in the ...
Asıcıoglu Osman O Department of Obstetrics and Gynecology, Sisli Etfal Training and Research Hospital, Istanbul, - - 2013
Objective This study compared two methods of expanding the uterine incision at the time of cesarean delivery, which is associated with the risk of unintended extension. Study Design This randomized trial included 1,076 women who underwent elective cesarean delivery. The primary outcome measure was the incidence of unintended extension related to the ...
- - 2013
The aims were to evaluate whether any changes in blood flow in fetal inferior vena cava (IVC) are observed during Atosiban tocolysis within the first 48 hours of therapy. Detailed Doppler evaluation of blood flow in fetal IVC was performed prior to Atosiban administration and after 24 and 48 hours ...
Nishida Yoshihiro - - 2013
Abstract Objective. The aim is to evaluate intrapartum fetal oxidative stress in real-time by umbilical cord blood dimethyl sulfate (DMSO)-induced ascorbyl free radical (AFR) measured by an electron spin resonance (ESR) method. Methods. 75 mothers delivering at gestational age after 37 weeks were recruited. They were divided into three groups: ...
Bendon Robert W - - 2013
Abstract Objective: Intrapartum fetal heart rate decelerations and bradycardia are often attributed to umbilical cord occlusion without knowing the anatomic basis of that occlusion. We hypothesized that umbilical cord twisting while looped around fetal parts could occlude blood flow. Methods: Using an in vitro preparation, human umbilical cord veins were ...
Fittschen M - - 2013
The aim of the present cross-sectional prospective study was to establish Doppler reference ranges for blood flow velocity waveforms (V max, V mean and V min) and resistance indices (PI, RI) of the fetal pulmonary arteries using the new pulsed-wave color advanced dynamic flow (ADF) Doppler technique. Data were collected ...
Kumpel Belinda - - 2013
Quantitation of fetomaternal hemorrhage (FMH) is performed to determine the dose of prophylactic anti-D (RhIG) required to prevent D immunization of D- women. Flow cytometry (FC) is the most accurate method. However, maternal white blood cells (WBCs) can give high background by binding anti-D nonspecifically, compromising accuracy. Maternal blood samples ...
Heppelmann M - - 2013
The objective of this study was to investigate the effects of puerperal uterine disease on uterine blood flow using trans-rectal Doppler sonography. Lactating Holstein Friesian cows (n=44) were divided into two groups based on whether they were healthy (UD-; n=23) or had uterine disease (UD+; n=21) defined as retained fetal ...
Savini Vincenzo - - 2013
Enterococcus hirae is rarely collected from man, while it is a common pathogen in mammals and birds. We describe the first isolation of the organism (strain DSM 27815) from human umbilical cord blood (UCB), thus emphasizing the risk of contamination of UCB units for clinical use. In this context, we ...
van Besien Koen - - 2013
Abstract The 11th international Cord Blood Meeting was devoted to advances in umbilical cord blood research and transplantation. Results of cord blood transplant (UCB-SCT) for congenital storage disease and hemoglobinopathies are encouraging, but UCB-SCT may also be useful for older adults with hematologic malignancies and UCB have potential in regenerative ...
Grzesiak Mariusz M Department of Feto-Maternal Medicine and Gynecology, "Polish Mother" Memorial Research Institute, Lodz, Poland. - - 2013
OBJECTIVEs: The aims were to investigate whether any changes in placental and fetal circulation were observed during fenoterol tocolysis within the first 48 hours of therapy. Doppler evaluation of placental and fetal circulation was performed prior to fenoterol administration and then after 24 and 48 hours. Maternal heart rate and ...
Grzesiak Mariusz M Department of Feto-Maternal Medicine and Gynecology, "Polish Mother" Memorial Research Institute, Lodz, Poland. - - 2013
to investigate whether any changes in the preload index (PLI) occur within the first 48 hours of fenoterol intravenous tocolysis. Doppler evaluation of placental and fetal circulation was performed in 36 pregnant women prior to fenoterol administration and after 24/48 hours. Measurements were obtained from a longitudinal section of the ...
Beharier Ofer - - 2013
S100B is a brain damage biomarker. When measured immediately after birth it reflects neonatal brain damage following asphyxia. In this study we used feticide as a novel model of fetal brain damage. We examined whether such damage is reflected by a rise in S100B in maternal blood before delivery. Eight ...
Deng Li - - 2013
To reduce massive and potentially fatal hemorrhage during cesarean section (CS) delivery because of the transverse incision through the lower uterine segment and placenta in central placenta previa (CPP), especially the type in which the placenta attaches to the anterior wall of the uterus. Thirty-four patients with CPP were enrolled ...
Dzięcioł Michał - - 2013
The aim of the study was to evaluate the influence of the Sildenafil citrate on the blood flow in the uterus of cows during dioestrus. Uterine blood flow was examined in five, healthy, adult cows. Between day 6-8 of the ovarian cycle, each cow received 200mg of sildenafil diluted in ...
Csorba Roland - - 2013
Previous studies have dealt with maternal blood rheology in preeclampsia (PE), but only a few focused on the fetal rheological parameters in this maternal state. PE is one of the most common severe complications of pregnancy world-wide associated with high maternal morbidity and mortality and intrauterine fetal growth restriction. Our ...
Drury Paul P - - 2013
Preterm brain injury is partly associated with hypoxia-ischemia starting before birth. Excessive nitric oxide production during HI may cause nitrosative stress, leading to cell membrane and mitochondrial damage. We therefore tested the hypothesis that therapy with a new, selective neuronal nitric oxide synthase (nNOS) inhibitor, JI-10 (0.022mg/kg bolus, n=8), given ...
Cohen Marta Cecilia - - 2013
Abstract Release of nucleated red blood cells (nRBCs) into the peripheral blood occurs in stillbirths/neonates with a probable hypoxic mode of death and antenatal stress. We correlate the number of nRBCs in the placenta with the occurrence of intradural (IDH) and subdural hemorrhage (SDH) and its potential link with fetal ...
Karagiorgou Louiza Z - - 2013
Umbilical cord blood supplies in Greece are not sufficient to meet the high transfusion needs. This study was designed to determine Greeks' opinion about umbilical cord blood, identify the reasons for the lack of motivation to donate umbilical cord blood and allow experts to establish better recruitment campaigns to enrich ...
Flo K - - 2013
To compare uterine artery volume blood flow (Quta ), vascular resistance (Ruta ), pulsatility index (Uta PI), and the fraction of maternal cardiac output (CO) distributed to the uteroplacental circulation in pregnant women with and without a previous caesarean section. Cross-sectional observational study. University hospital in Norway. Thirty-two pregnant women with ...
White Christopher R H - - 2013
There is growing support for umbilical cord blood gas analysis (UCBGA) to be conducted at delivery. A recent study in a tertiary level obstetric unit found that universal UCBGA was associated with improved perinatal outcomes, but there is less evidence of benefit in lower-risk environments. In such settings, lactate analysis ...
Hoffman-Zacharska Dorota D Department of Medical Genetics, Institute Mother and Child, 01-211 Warsaw, Kasprzaka 17, - - 2013
Uterine and umbilical blood flow measurements are reviewed in terms of studies carried out in uncomplicated human pregnancies. The review includes the perspective of how those estimates of flow fit with current knowledge of human fetal O2 consumption and uterine O2 and glucose consumption. From the consideration of both the ...
Battaglia Frederick C FC University of Colorado School of Medicine, Pernatal Research Center, 13243 East 23rd Avenue, F441, Aurora, CO 80045 USA, - - 2013
Uterine and umbilical blood flow measurements are reviewed in terms of studies carried out in uncomplicated human pregnancies. The review includes the perspective of how those estimates of flow fit with current knowledge of human fetal O2 consumption and uterine O2 and glucose consumption. From the consideration of both the ...
Yang Juan - - 2013
The precise quantitation of smoking during pregnancy is difficult in retrospective studies. Routinely collected blood specimens from newborns, stored as dried blood spots, may provide a low-cost method to objectively measure maternal smoking close to the time of delivery. This article compares cotinine levels in dried blood spots to those ...
Lee A I AI Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. Electronic address: - - 2013
There are currently no standard recommendations regarding the dose, rate, or duration of intravenous oxytocin administration for the active management of the third stage of labor in the USA. In 2008, we initiated a standardized postpartum oxytocin protocol for active management of the third stage of labor. In cesarean deliveries, ...
Karnpean Rossarin - - 2013
Introduction: With the lack of fetal blood specimens in routine practice, little is known about red blood cell (RBC) parameters of fetuses with various thalassemia syndromes. This study aimed to describe these in various forms of thalassemia. Materials and Methods: The study was performed on 93 fetal blood specimens obtained ...
Nalbant Demet - - 2013
Background:Study of the pathophysiology and treatment of anemia of prematurity is facilitated by direct measurement of red cell volume (RCV) utilizing microliter quantities of blood samples. Our objective was to compare concurrent measurements of multiple direct RCV methods in infants.Methods:Eighteen preterm infants receiving clinically indicated transfusions had concurrent flow cytometric ...
Gupta Anshu A Department of Pharmacology, MMIMSR, Ambala, - - 2013
Postpartum hemorrhage is most common cause of maternal mortality. Active management of third stage of labor minimizes the risk of postpartum hemorrhage. To compare the effect of methylergonovine and 15-methyl prostaglandin F2α (15-methyl PGF2α) in active management of third stage of labor. A randomized open labelled parallel study with 50 ...
Prior Tomas - - 2013
To investigate the distribution of umbilical venous flow rates, measured in early labour, in a cohort of normal term pregnancies, and to establish the relationship between umbilical venous flow and subsequent intra-partum outcome. Five hundred and eighty nine women with uncomplicated, term, singleton pregnancies, were recruited to this prospective observational ...
Venditti Carolina C - - 2013
End- tidal breath carbon monoxide (CO) is abnormally low in women with preeclampsia (PE), while women smoking during pregnancy have shown an increase in CO levels and a 33% lower incidence of PE. This effect may be in part due to lowered sFLT1 plasma levels in smokers, and perhaps low- ...
Poret-Bazin H - - 2013
Contrast enhanced ultrasound (CEUS) was used to quantify the dynamic changes in uteroplacental blood flow before and after the interruption of fetal villus circulation resulting from feticide during a second trimester pregnancy termination in a patient with complete placenta previa. Quantitative analysis was performed on time-intensity curves acquired 24 h before ...
Herberth Gunda - - 2013
There is evidence that microRNAs (miRNAs) are sensitive to environmental stressors, including tobacco smoke. On the other hand, miRNAs are involved in immune regulation, such as regulatory T (Treg) cell differentiation. The aim of the present study was to investigate the association between prenatal tobacco smoke exposure, miRNAs, and Treg ...
El-Mazny Akmal - - 2013
To evaluate uterine artery blood flow using pulsed Doppler, and endometrial and subendometrial microvascularization using three-dimensional (3D) power Doppler, in women with unexplained infertility. In a prospective clinical trial at a university teaching hospital, 40 women with unexplained infertility were compared to 40 fertile parous controls. In the mid-luteal (peri-implantation) ...
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