Search Results
Results 751 - 800 of 872
< 8 9 10 11 12 13 14 15 16 17 18 >
Swierczek J S - - 1982
Human pancreatic polypeptide (HPP) was infused into 6 anesthetized dogs at a constant dose of 1.0 micrograms/kg/h over 60 min. Blood samples for RIA of pancreatic polypeptide were taken repeatedly from a carotid artery, jugular vein, femoral vein, renal vein and mesenteric vein. The calculated tissue removal of HPP in ...
Szabó G - - 1982
In the rabbit hindleg lymph and tissue fluid were collected before and during close intraarterial infusions of histamine (2.5 and 10 micrograms/min) or bradykinin (0.4 microgram/min). Protein concentration was higher in the tissue fluid than in the lymph. During the 2h of the experiment in the control animals protein concentration ...
Kramer G C - - 1981
We studied the effects of reducing the plasma protein concentration on flow and composition of pulmonary lymph in 12 unanesthetized sheep. Whole blood was removed while red cells were returned and lactated Ringers was infused at a rate sufficient to maintain pulmonary vascular pressures at baseline values. A 44-54% reduction ...
Renkin E M - - 1981
Hind paws of anesthetized dogs were exposed to moderate continuous heat (45--52 degrees C). Lymph flow (L) was increased to 5.61 (SD 3.26) times control levels, lymph:plasma concentration ratios for total plasma protein (RT) were increased to 3.23 (SD 1.33), and for exogenous Dextran-110 (RD) to 8.41 (SD 4.00) times ...
Drake R - - 1981
Many investigators have used the chronic sheep lung lymph preparation to collect caudal mediastinal node (CMN) efferent lymph. These investigators have assumed that the lymph collected with the preparation is almost pure lung lymph. We examined 17 sheep for possible systemic contamination to the lymph, and in each sheep we ...
Mayer J E JE - - 1981
The effects of transfusion of whole blood clot emboli and aged citrated platelet-poor plasma on pulmonary capillary permeability were investigated in anesthetized sheep by continuous collection of pulmonary lymph. Changes in lymph flow and lymph-to-plasma ratios (CL/CP) for albumin and globulin were utilized to detect changes in permeability. Infusion of ...
Inoue K - - 1981
Studies were conducted to investigate the relationship between development of fibrosis and hemodynamic changes in the pancreas in dogs. The basal blood flow rate in the atrophied, fibrotic pancreas was preserved at almost the same level as in the normal pancreas. Fibrotic pancreas responded to VIP with increased blood flow, ...
Konturek S J - - 1981
In five dogs with gastric fistulas, Heidenhain pouches, and pancreatic fistulas, the effects of substance P (SP) and its C-terminal hexapeptide (SP6-11) on gastric acid and pancreatic secretions were determined under basal conditions and in response to secretory stimulation. SP or SP6-11 infused alone in graded doses (0.25-2.0 nmol.kg-1.h-1) caused ...
Levitt M D - - 1981
The possible existence of an enteropancreatic circulation of amylase was investigated in the dog. Endogenous amylase concentration in pancreatic venous blood was consistently greater than that in arterial blood, indicating a net flux of amylase from the pancreas to blood. Less than 0.02% of the metabolic clearance of 125I-amylase was ...
Lawrence J A - - 1981
The effects of natural porcine and synthetic secretin, given by intravenous bolus or infusion, on intestinal lymph flow and protein composition in unanaesthetized rats were studied. Both forms of secretin increased lymph flow and protein output from the lymph fistula; dose-response relationships were determined. No change was observed in protein ...
Maruyama M - - 1981
In dog trachea in situ, perfused arterially with blood, isoprenaline, glyceryl trinitrate and N-nitroso-N-morpholinoamino-acetonitrile (SIN-1A) given intra-arterially, decreased tracheal tone which had been elevated by neostigmine and increased tracheal blood flow. Glyceryl trinitrate and SIN-1A were more effective on the tracheal musculature than on the tracheal vasculature whereas isoprenaline was ...
Otsuki M - - 1981
Pancreatic juice flow and amylase output, and the concentrations of immunoreactive secretin in portal and peripheral blood were simultaneously determined in anesthetized rats in response to intraduodenal instillation of 1-phenyl-1-hydroxy-n-pentane (PHP), a phenyl carbinol derivative induced from one of the constituents of Curcuma. PHP stimulated both pancreatic juice flow and ...
Osnes M - - 1981
Recovery of pancreatic juice was studied by endoscopic cannulation of the main pancreatic duct, using a double-lumen catheter and infusion of a marker solution (57Co-labeled vitamin B12) into the pancreatic duct. Juice was collected by siphonage. Tracer amounts of 91Cr were infused into the duodenum through a separate catheter attached ...
Schröder T - - 1981
Acute pancreatitis was induced in 20 piglets. In the controls (10 piglets) no specific treatment was given, while in the experimental group the animals were treated with chlorpromazine, a potent phospholipase A2 inhibitor in vitro. Blood samples were taken from all animals for the assay of amylase, lipase, phospholipase A2, ...
Jansson L - - 1981
A technique is described for visualization of the pancreatic islets in the rat by simple dark field illumination of pieces of the frozen and thawed pancreas. By using this method, microspheres, injected for studies of the capillary blood flow, can be readily located and counted in both the islets and ...
Seeliger K - - 1981
We describe the feasibility of transjugular endovascular visualization and cannulation of the canine cervical thoracic duct using a flexible cholangioscope modified for lymphoscopy. The lymphoscope is composed of a prismatic side-view optic with a catheter guide channel attached by a metal cap to the terminal end. The technique has clinical ...
Lebenthal E - - 1980
It has been noted that from days 18 to 22 (birth) during the second intrauterine period of morphogenesis of the rat pancreas the accumulation of enzymes increases dramatically. We studied the effect of altered maternofetal blood flow on the development of the rat pancreas during the critical second period. Our ...
Inoue K - - 1980
The effects of synthetic chicken VIP (an octacosapeptide corresponding to the entire sequence of chicken VIP) on pancreatic blood flow and on systemic arterial pressure was examined in dogs. The relationship between pancreatic blood flow and systemic arterial pressure in response to synthetic chicken VIP was also investigated. Pancreatic blood ...
Lifson N - - 1980
Nonradioactive microspheres of various sized (mean batch diameters ranging from 6 microns ato 26 microns) were administered to unfasted rabbits under sodium pentobarbital anesthesia by a brief injection into the left ventricle. Flow rate per bead was determined by the reference organ method. After prompt death of the animal, the ...
Haberich F J - - 1980
1. Two surgical methods are described to derive bile and pancreatic juice separately by indwelling catheters in rats. 2. The secretes are always recirculated into the animals duodenum, the indwelling catheters forming an extracorporal loop. 3. The experiments are performed in the conscious animal. 4. The flow rate of the ...
Konturek S J - - 1980
Prostacyclin (PGI2), the major product of arachidonate metabolism in the gastrointestinal tract, was shown to affect gastric blood flow and gastric secretion, but it is unknown whether it also affects pancreatic secretion. This study was designed to determine the influence of PGI2 on pancreatic secretion under basal conditions and in ...
Donaldson L A - - 1980
A dog model was established to measure the hemodynamic changes occurring during experimental pancreatitis. The effect of treatment with Trasylol and vasopressin, beginning 60 minutes after induction of pancreatitis was assessed by their effect on the pancreatic hemodynamics. The pancreatic arterial blood flow fell by 72 per cent in the ...
McCaffrey C - - 1980
Furosemide 20 mg/kg was given intravenously to 12 anesthetized dogs with clamped renal pedicles. Thoracic duct lymph flow (TDLF) increased promptly by 38% (P less than 0.05), an increment that lasted 80 min. Because in 6 of 12 dogs there was a transient increase in splanchnic blood flow, in separate ...
Holst J J - - 1980
We studied the effect of varying oxygen supply on the endocrine and exocrine secretions of the isolated perfused porcine pancreas utilizing completely synthetic perfusion medium with and without the addition of erythrocytes. With synthetic medium oxygenated to a Po2 of 500 mmHg, oxygen consumption was constant for flow rates at ...
Kaufman H S - - 1980
The WBC and per cent polymorphonuclear cells in blood increased significantly during the approximately 3 hours of the experiments. The number of lymphocytes did not change significantly. Corresponding cellular components in RD and TD lymph were not significantly different. The per cent of T-rosettes in FVB was more than three ...
Donaldson L A - - 1980
There is no accepted specific treatment for acute pancreatitis in man in spite of extensive investigations. Evidence is presented based on histology, vascular and blood flow studies to support the hypothesis that acute pancreatitis is unlike most inflammatory conditions since a rapid and severe ischaemia develops in the pancreas. In ...
Nyman U - - 1980
Injections of non-ionic monomeric (metrizamide, C29 and iohexol) and monoacidic dimeric (ioxaglate) contrast media into the femoral artery of dogs caused significantly less increase in the rate of femoral blood flow than the more hypertonic ionic monomeric compound metrizoate at equivalent iodine concentrations. The effect of metrizoate was similar to ...
Falls R - - 1980
The adult respiratory distress syndrome has been associated with acute pancreatitis in 5-8% of patients. to determine, in a quantitative manner, the effects of acute, hemorrhagic pancreatitis on alveolar epithelial permeability, we studied two groups of dogs (group 1 - sham-operated, 7 dogs; group 2 - surgically induced pancreatitis, 7 ...
Hartmann W - - 1980
In the anesthetized cat duodenal perfusion with Na-taurocholate (TC, 0.2 M, pH 6.1, 290 mosmol, 45 ml x h-1) stimulated pancreatic volume (0 to 326 +/- 236 mg x 10 min-1) and bicarbonate secretion (0 to 34.2 +/- 4.1 mumol x 10 min-1), whereas pancreatic enzyme output was sparse. Simultaneously ...
Tønder K J - - 1980
The present summary is a review and a discussion of the following papers (I-V), submitted as partial fulfillment of the requirements for the degree of Doctor Odontologiae at the University of Bergen. I. Blood flow in the dental pulp in dogs measured by local H2 gas desaturation technique. Arch. Oral ...
Jonsson C E - - 1979
Leg lymph was collected from pentobarbital anaesthetized rabbits before and after scalding injury of the paw (75 degrees C for 20 s), and the contents of cyclic AMP (cAMP), prostaglandin E2 (PGE2) and PGF2 alpha and thromboxane B2 (TXB2) in lymph were determined. After injury lymph flow increased about four ...
Ekino S - - 1979
The fine distribution of lymph vessels in the bursa of Fabricius and the efferent lymph vessels coming from the bursa were demonstrated. The lymph vessels never entered lymphoid follicles, whereas the blood vessels pierced the cortex of lymphoid follicles and formed a network at the boundary between the cortex and ...
Donaldson L A - - 1979
A canine model was devised to measure the oxygen consumption of the pancreas in experimentally induced pancreatitis. Over the 120 minute investigation period the oxygen consumption fell by 63% in the presence of a diminishing pancreatic blood flow and constant arteriovenous percentage saturation across the pancreas. Dextran 40 has been ...
Merikanto J - - 1979
Lymphocytes obtained from thymus, spleen and heart blood of 33-day-old guinea-pig foetuses and from lymph nodes of 48-day-old foetuses onwards were stimulated by phytohaemagglutinin (PHA). concanavalin A (Con A) and dextran sulphate (DxS). The results, based on the analysis of ninety-five foetuses, indicated that the mitogenic responses of the guinea-pig ...
Fahrenkrug J - - 1979
The role of nerves that liberate vasoactive intestinal polypeptide (VIP) in the porcine pancrease as mediators of the atropine-resistant action of the vagus on flow and bicarbonate (HCO3) secretion was examined. Efferent electrical stimulation of the vagus in atropinized pigs produced a profuse flow of pancreatic juice with high HCO3 ...
Gee M H - - 1979
In animals with edema, pulmonary and systemic lymphatics may function to remove accumulated extravascular fluid in addition to responding to events as they occur in the exchanging vessels. We tested this hypothesis by measuring the flow rate and composition of thoracic duct and right duct lymph in anesthetized dogs made ...
Michael L H - - 1979
The cardiac lymphatic duct was cannulated in dogs and the exteriorized cannula allowed chronic collection of lymph during the awake state for as long as 3 wk. The surgical methodology and inherent difficulties in the technique are describ:d. Cardiac lymph flow ranged from 0.45--5.6 ml/h in the control state in ...
Scott G W - - 1979
The canine cystic duct, like that in man, has an extremely thin layer of muscle deep to the mucosal layer, surrounded by a dense layer of collagen fibers. The resistance to flow through the duct was studied in 16 anesthetized dogs by perfusing the duct with saline solution at constant ...
Ottaway C A - - 1979
The relationship of alterations in blood flow with changes in cell distribution has been studied in an inflammatory site and its draining lymph node during the induction of an immune reaction with oxazolone in mice. The cells which move to the site of inflammation are predominantly lymphoblasts and their increased ...
Caflisch C R - - 1979
An improved pCO2 microelectrode has been evaluated and used to investigate whether a significant barrier to diffusion of CO2 exists in the rabbit pancreas. The results of this study show the improved Carter and Caflisch pCO2 microelectrode to be an accurate and reliable tool for measuring pancreatic venous and ductal ...
Thommesen P - - 1979
In 10 out of 12 patients, there was a significantly stimulatory effect on lymph flow during taste and in 9 out of 10 patients there was a significant stimulatory effect on lymph flow during mastication. The stimulatory effect of mastication could be a parallel to the conditions observed in the ...
Mountford R A - - 1979
Pathologically enlarged lymph nodes have been examined with a commercially available 10 MHz continuous-wave Doppler flowmeter. Many enlarged lymph nodes gave rise to significant Doppler-shift signals indicating increased blood flow. The signals have been spectrum analysed and the large diastolic flow components suggest that there is considerable arterio-venous shunting within ...
Alteveer R J - - 1979
Surgical procedures are detailed that have yielded for the first time an in vivo vascularly isolated, autoperfused preparation of the entire pancreas in anesthetized dogs. Previous studies had isolated only part of the pancreas or had resorted to blood-flow techniques not requiring pooled pancreatic venous blood, necessary for metabolic studies ...
Engeset A - - 1979
The passage from blood to peripheral lymph of 131I-labeled human serum albumin has been studied in 6 male patients (30-70 years) with malignancies without metastases. On the first day the concentration of radio-labeled albumin in the blood was kept almost constant by repeated i.v. injections. Lymph was collected continuously from ...
Herman P G - - 1979
We have assessed the effects of antigenic stimulation on the regional blood flow of the lymph node. In seventeen New Zealand white rabbits, the regional blood flow to the popliteal lymph nodes was determined using 9 and 15 micron microspheres at 16, 40, and 144 h following antigen administration. The ...
Szwed J J - - 1979
1. Simultaneous thoracic duct and hepatic lymph flows were measured in 29 mongrel dogs before and after the intravenous administration of mannitol, ethacrynic acid, frusemide and chlorothiazide in separate experiments. 2. Thoracic duct lymph flow increased significantly after each diuretic agent was administered. 3. Hepatic lymph flow increased only after ...
Gaffney G R - - 1979
Furosemide has been reported to cause pathological changes in the intestines as a consequence of the decrease in splanchnic blood flow that it produces. In view of the pancreatic toxicities of this diuretic, it was of interest to examine the effect of the agent on blood flow to this organ. ...
Beijer H J - - 1979
Time-effect relationship and sensitivity of pancreatic exocrine secretion and pancreatic blood flow were established, to test the supposition that blood flow to the pancreas is controlled by the secretory process. Pancreatic exocrine secretion rate was stimulated by incremental iv doses of secretin (Karolinska, 0.001--4 U/kg) in pentobarbital anesthetized dogs. Arterial ...
Szabó G - - 1979
The effect of several diuretic agents on thoracic duct and right lymph trunk lymph flow, and on some other parameters was examined in normal dogs and dogs with ascites produced by the constriction of inferior cava vein. In normal animals furosemide and etacrynic acid in diuretic doses did not influence ...
Orlov V - - 1978
Three chief components of the kallikrein-kinin system (kallikrein, kininogen, kininase) were studied in the blood of 42 patients with acute pancreatitis. Significant increase in content of kallikrein, decrease in level of kininogen, and increase of kininase activity were observed. The highest values for kallikrein, kininogen and kininase activity were found ...
< 8 9 10 11 12 13 14 15 16 17 18 >