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Albert Scott S Chemical and Biomolecular Engineering Department, Lafayette College, Easton, PA 18042, - - 2014
The structure and function of the renal artery ostium flow diverter on the caudal side of the renal branch point were previously reported; in this study, we further evaluate the diverter׳s possible functions. The protrusion of this structure into the abdominal aorta suggests that the diverter may preferentially direct blood ...
Cutajar Marica M Imaging and Biophysics Unit, UCL Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK, - - 2014
To investigate the reproducibility of arterial spin labelling (ASL) and dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) and quantitatively compare these techniques for the measurement of renal blood flow (RBF). Sixteen healthy volunteers were examined on two different occasions. ASL was performed using a multi-TI FAIR labelling scheme with a ...
Veenstra G G Medical Centre Leeuwarden, ICU, Leeuwarden, the Netherlands. Electronic address: - - 2014
Acute kidney injury (AKI) is a well-known complication in critically ill patients. Little is known about the timing and the ultrafiltration dose after initial resuscitation. In vivo microscopy of the microcirculation has been suggested as alternative for the assessment of volume status. Previous studies contribute to the understanding that intravascular ...
Frithiof Robert R Uppsala - - 2014
Hypertonic NaCl infused into the carotid arteries increases arterial blood pressure (AP) and changes sympathetic nerve activity (SNA) via cerebral mechanisms. We hypothesized that elevated sodium levels in the blood supply to the brain would induce differential responses in renal and cardiac SNA via sensors located outside the blood-brain barrier. ...
Aseem Obaidullah O Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina; Charleston, South Carolina, - - 2013
Cubilin is an endocytic receptor highly expressed in renal proximal tubules, where it mediates uptake of albumin and filtered forms of apoA-I/HDL. Cubilin deficiency leads to urinary loss of albumin and apoA-I; however, the consequences of cubilin loss on the homeostasis of blood albumin and apoA-I/HDL have not been studied. ...
Chowdhury Abeed H - - 2013
We compared the effects of intravenous administration of 6% hydroxyethyl starch (maize-derived) in 0.9% saline (Voluven; Fresenius Kabi, Runcorn, United Kingdom) and a "balanced" preparation of 6% hydroxyethyl starch (potato-derived) [Plasma Volume Redibag (PVR); Baxter Healthcare, Thetford, United Kingdom] on renal blood flow velocity and renal cortical tissue perfusion in ...
Klingensmith William C WC - - 2013
Testing the rate of creatinine clearance by measuring the level of creatinine in the blood and in a 24-h urine collection is a common method of evaluating renal function. The result is routinely normalized for body surface area (BSA). Alternatively, renal clearance can be measured by (99m)Tc-mercaptoacetyltriglycine (MAG3) renal imaging ...
Mitrou Nicholas Ga - - 2013
Renal autoregulation maintains stable renal blood flow in the face of constantly fluctuating blood pressure. Autoregulation is also the only mechanism that protects the delicate glomerular capillaries when blood pressure increases. In order to understand autoregulation, the renal blood flow response to changing blood pressure is studied. The steady-state response ...
Burban Melanie - - 2013
The relationships between systemic hemodynamics and renal blood flow and renal microcirculation are poorly known in sepsis. Norepinephrine (NE) infusion may add another level of complexity. Ventilated and anesthetized rats were submitted to various mean arterial pressure (MAP) steps by blood removal, in presence and absence of sepsis and/or NE. ...
Ramón de Fata F - - 2013
Percutaneous nephrolithotomy (PCNL) is the minimally invasive procedure of choice for removing renal stones larger than 2cm. This study has aimed to identify the different variables that might influence decrease of hemoglobin during the surgery performed in supine position. A prospective, multicenter, observational study of supine PCNL, based on the ...
Park Sung-Hong - - 2013
We implemented pseudo-continuous ASL (pCASL) with 2D and 3D balanced steady state free precession (bSSFP) readout for mapping blood flow in the human brain, retina, and kidney, free of distortion and signal dropout, which are typically observed in the most commonly used echo-planar imaging acquisition. High resolution functional brain imaging ...
Tirilomis Theodor - - 2013
Renal blood flow (RBF) may vary during cardiopulmonary bypass and low flow may cause insufficient blood supply of the kidney triggering renal failure postoperatively. Still, a valid intraoperative method of continuous RBF measurement is not available. A new catheter combining thermodilution and intravascular Doppler was developed, first calibrated in an ...
Soni Hitesh - - 2013
Renal expression of the peptide hormone urotensin II (UII) and its receptor (UTR) are dependent on kidney maturation and anatomical regions. However, renal regional hemodynamic effects of UII in neonates are unclear. Here, we investigated regional hemodynamic responses to acute intrarenal arterial administration of UII in newborn pigs. Western immunoblotting ...
Wentland Andrew L AL Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI, USA 53705-2275, USA. - - 2013
The aim of this study was to assess the repeatability and internal consistency of flow measurements in the renal arteries and pararenal aorta with the use of standard two-dimensional (2D) and novel four-dimensional (4D) phase contrast (PC) magnetic resonance imaging (MRI). Ten healthy volunteers were imaged with a radially undersampled ...
Maciel Alexandre Toledo - - 2013
ABSTRACT: Urinary sodium (NaU) is one of the oldest parameters used in the evaluation of azotemia and oliguria. Over the past years, however, it has progressively been considered as obsolete and useless, especially in sepsis. It is common sense that NaU frequently does not correlate well with global renal blood ...
Vricella Gino J - - 2013
WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: There is a paucity of population-based analyses of expected outcomes after renal surgery for kidney cancer. Reported blood transfusion rates after nephrectomy show considerable variability, probably as a result of the referral patterns that influence reports from tertiary academic ...
Lu Qian - - 2013
Translation elongation factor-1d (TEF-1δ) has been identified as a novel cadmium-responsive proto-oncogene. However, it is still unclear whether TEF-1δ could be a potential biomarker of cadmium exposure. Rats were treated with CdCl2 at different concentrations (high dose 1.225, mid-dose 0.612 and low dose 0.306 mg/kg body weight, respectively) for 14 ...
Maciel Alexandre Toledo AT Intensive Care Unit, Department of Medical Emergencies, Hospital das Clínicas University of São Paulo, São Paulo, Brazil. - - 2013
Sequential physicochemical alterations in blood and urine in the course of acute kidney injury (AKI) development have not been previously described. We aimed to describe these alterations in parallel to traditional renal and acid-base parameters. One hundred and sixty eight consecutive critically ill patients with no previous kidney disease, who ...
Charen Elliot E Division of Nephrology and Hypertension, Beth Israel Medical Center, New York, NY, USA. - - 2013
The case documented here represents the longest course of continuous-flow peritoneal dialysis (PD) reported in the literature. A 61-year-old man with hepatorenal syndrome type 1 and ascites presented with hypotension and bright red blood per rectum and was found to be in acute renal failure with severe anemia. Continuous-flow PD ...
Shimmer C C Department of Cardiothoracic and Thoracic Vascular Surgery, University Hospital Würzburg, Würzburg, - - 2013
To identify the impact of storage time and amount of transfused red blood cell units on renal function. Consecutive transfused patients (n=492), undergoing cardiac surgery at a single centre and receiving at least one red blood cell unit, were pooled in different groups depending on storage time and amount of ...
Amador Carolina C Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, United States, Ultrasound Research - - 2013
Elasticity imaging methods have been used to study kidney mechanical properties and have demonstrated that the kidney elastic modulus increases with disease state. However, studies in swine suggests that kidney elastic modulus is also affected by hemodynamic variables. A newly emerging method called Shearwave Dispersion Ultrasound Vibrometry (SDUV) offers a ...
Sugimori Hiroko - - 2012
Increased blood viscosity reduces blood flow and elevates vascular resistance in the cardiovascular system. The aim of this study was to elucidate how blood viscosity could affect renal function and eventually contribute to renal damage in essential hypertensives (EHT). In 164 untreated EHT without apparent renal damage (96 men, 56±12 ...
Kennedy-Lydon T M TM Urinary System Physiology Unit, Royal Veterinary College, London, - - 2013
Regulation of medullary blood flow (MBF) is essential in maintaining normal kidney function. Blood flow to the medulla is supplied by the descending vasa recta (DVR), which arise from the efferent arterioles of juxtamedullary glomeruli. DVR are composed of a continuous endothelium, intercalated with smooth muscle-like cells called pericytes. Pericytes ...
Rogachev Boris - - 2012
PURPOSE: The purpose of the present study is to investigate whether hemodialysis (HD) is effective in lowering blood glutamate levels. In addition, we examined the effect of HD on glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT) levels in the blood and described the rate and pattern of blood ...
M Subha Palaneeswari - - 2012
In India, there is rising burden of chronic diseases like hypertension and diabetes. It has been estimated that 25-40% of these patients are likely to develop CKD, with a significant percentage requiring renal replacement therapy. Haemodialysis is the most common method which is used to treat advanced and permanent kidney ...
Schenker M C - - 2012
The flow in a confined container induced by an ultrasonic horn is measured by Particle Image Velocimetry (PIV). This flow is caused by acoustic streaming and highly influenced by the presence of cavitation. The jet-like experimentally observed flow is compared with the available theoretical solution for a turbulent free round ...
Alarifi Saud - - 2012
Gentamicin is an effective widely used antibiotic, but the risk of nephrotoxicity and oxidative damage limit its long-term use. Hence, the current study aims to elucidate such hazardous effects. To achieve the study aim male Wistar albino rats (Rattus norvegicus) were exposed to gentamicin to investigate the resultant blood chemical ...
Boryskina Olena P - - 2011
Comment on: Boryskina OP, et al. Eur Phys J-Appl Phys 2011; 55: 21101.
Heusch Gerd - - 2011
Activation of coronary vascular α-adrenoceptors results in vasoconstriction which competes with metabolic vasodilation during sympathetic activation. Epicardial conduit vessel constriction is largely mediated by α(1)-adrenoceptors; the constriction of the resistive microcirculation largely by α(2)-adrenoceptors, but also by α(1)-adrenoceptors. There is no firm evidence that α-adrenergic coronary vasoconstriction exerts a beneficial ...
Mohseni Michael - - 2011
Prior reports on metabolic derangements observed in distance running frequently have small sample sizes, lack prerace laboratory measures, and report sodium as the sole measure. Metabolic abnormalities-hyponatremia, hypokalemia, renal dysfunction, hemoconcentration-are frequent after completing a full or half marathon. Clinically significant changes occur in these laboratory values after race completion. ...
Zaky Saad - - 2011
The aim of this study was to investigate the effect of rectal ozone on portal vein oxygenation and the pharmacokinetic changes of propranolol in patients with liver cirrhosis. Fifteen patients with liver cirrhosis were included They were given a fixed oral dose of propranolol 80mg on the morning of day ...
Clark G T - - 2011
The use of dried blood spots (DBS) in preclinical studies has seen an enormous increase over the past two years. Despite its positive impact on the 3Rs (reduce, replace and refine), its uptake in exploratory drug discovery has been limited due mainly to protracted method development time in bioanalysis but ...
Herzog K - - 2011
The objectives of this experiment were to characterize luteal blood flow in pregnant and non-pregnant cows and to determine its value for early pregnancy diagnosis. Lactating dairy cows (n = 54), 5.2 ± 0.2 y old (mean ± SEM), average parity 2.4 ± 0.2, and ≥ 6 wk postpartum at ...
Johnson Andrew C - - 2010
Daily steroid estrogen concentrations as 17β-estradiol equivalents (E2 equiv.) were modeled from 1992 to 2008 for single locations on the well populated Thames and Soar rivers in England. The historic daily mean flow values which were the basis of this exercise came from a selected gauging site on each river. ...
Honnens Aenne - - 2011
The objective of this study was to investigate the relationships between uterine perfusion and estrogen, progesterone and the uterine nitric oxide synthase (NOS) system in five trotter mares during the estrous cycle. Color Doppler sonography for measurement of uterine blood flow and collection of blood for determination of plasma estrogen ...
Reho John J - - 2011
Background. The etiology of preeclampsia remains unclear. Animal modeling of preeclampsia has been useful; however, no model to date represents episodic changes in uteroplacental blood flow that may occur in preeclampsia. Objective. To develop a gravid rat model characterized by episodic reductions in uteroplacental blood flow. Method. Pregnant Sprague Dawley ...
Hussein Mostafa - - 2011
The main cause for discontinuation of depot medroxyprogesterone acetate (DMPA) use is irregular menstrual bleeding. The exact pathophysiological mechanisms of irregular bleeding have remained unclear. Transvaginal Doppler is a non-invasive method for studying changes in blood flow which may highlight the underlying pathology in those cases with irregular uterine bleeding. ...
Kikuchi Hiromi - - 2010
The purpose of this study was to evaluate mechanisms underlying the action of selective serotonin reuptake inhibitors on the improvement of negative mood symptoms in premenstrual syndrome. We assessed relationships between serotonin (5-HT) levels in the brain (estimated from 5-HT concentrations in whole blood) and negative mood states during the ...
Thuring A - - 2010
OBJECTIVE: To investigate the possibility of recording Doppler flow signals from the maternal uterine veins (UtVs) during pregnancy and to assess the relationship between UtV signals and other Doppler parameters as well as pregnancy outcomes. METHODS: Transabdominal Doppler ultrasound examination of the UtVs on both sides of the uterus was ...
Lee Dong-Yun - - 2010
OBJECTIVE: The aim of this prospective study was to evaluate the changes in the ovarian environment after hysterectomy based on ovarian arterial blood flow indices and serum anti-Müllerian hormone (AMH) levels. STUDY DESIGN: Ovarian arterial blood flow indices (pulsatile and resistance indices) by Doppler ultrasonography and serum AMH levels were ...
Bollwein H - - 2010
The goal of this study was to determine the effects of the length of the preovulatory phase on genital blood flow and mRNA expression of endometrial hormone receptors in cattle (Bos Taurus). Ovulation was synchronized in 50 Holstein-Friesian cows using a modified Ovsynch (ovulation synchronization) protocol, in which the second ...
Herzog K - - 2010
The objective of this study was to assess the reliability of luteal blood flow (LBF) as recorded by color Doppler sonography to monitor luteal function during the estrous cycle of dairy cows and to compare the results with that for the established criterion luteal size (LS) as determined by B-mode ...
Pates Jason A - - 2010
OBJECTIVE: The purpose of this study is to determine the feasibility of measuring total uterine blood flow in pregnancy using magnetic resonance imaging (MRI) technique. METHODS: Uterine blood flow was determined in pregnant women in whom MRI was being carried out to assess a fetal anomaly. A two-dimensional time-of-flight magnetic ...
Wilczak M - - 2010
Detection of neoplastic changes in the pelvis minor in early stages is a critical prognostic factor for patients suffering from uterine carcinoma. Due to the problem presented, the evaluation of clinical usefulness of ultrasonographic examination including color Doppler in the process of detecting pathologic changes within the endometrium was the ...
Siddiqui M A R - - 2010
Changes in echotexture and blood flow in the wall of preovulatory follicles in heifers were studied in relation to the LH surge and ovulation in gonadotrophin-releasing hormone-induced (n = 7; Experiment 1) and spontaneous (n = 8; Experiment 2) ovulators. Ultrasonographic examinations and blood sampling were performed either every hour ...
Aberdeen Graham W - - 2010
Although estrogen regulates important aspects of maternal cardiovascular physiology, the role of estrogen on uteroplacental and fetal blood flow is incompletely understood. This study tested the hypothesis that chronically suppressing endogenous estrogen production during the second half of baboon pregnancy alters uterine and fetal blood flow dynamics assessed by ultrasonography. ...
Rehfuss Alexandra - - 2010
There are a number of lower urinary tract dysfunctions (LUTD) that occur primarily in women. Our hypothesis is that cyclical estrogen will produce LUTD in part by the generation of free radicals and oxidative damage to cellular and subcellular membranes. Twenty female rabbits were divided into five groups: control, ovariectomized ...
Deurloo Koen L - - 2009
OBJECTIVE: The purpose of this study was to examine the longitudinal relationship between Doppler flow velocity waveforms of the spiral artery (SA) and uterine artery (UA) in pregnant women. METHODS: Ninety-seven primigravidas with uncomplicated singleton pregnancies were analyzed. Spiral artery and combined UA velocity waveforms were assessed by transabdominal color ...
Rigano S - - 2010
The primary aim of this pilot study was to study uterine artery (UtA) blood flow volume in uneventful human pregnancies delivered at term, at mid and late gestation by means of 3D and bi-dimensional ultrasound imaging with angio-Doppler combined with fluid-dynamic modeling. Secondary aims were to correlate flow volume to ...
Sekhavat Leila - - 2010
The purpose of this study was to determine whether the method used to expand the uterine incision (sharp vs. blunt) for cesarean section (CS) affects maternal blood loss. A prospective study conducted on 200 nulliparous who underwent lower segment transverse CS divided into two groups. One hundred women were assigned ...
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