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Peng Giia-Sheun GS aDepartment of Neurology, Tri-Service General Hospital bDepartment of Biochemistry, National Defense Medical Center, Taipei cDepartment of Psychiatry, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City dDepartment of Nursing, Chang Gung University of Science and Technology, Taoyuan, - - 2014
It has been well documented that variant alleles of both ADH1B*2 of alcohol dehydrogenase (ADH) and ALDH2*2 of aldehyde dehydrogenase (ALDH) protect against the development of alcoholism in East Asians. However, it remains unclear whether ADH1B*2 contributes significantly toward the accumulation of systemic blood acetaldehyde and whether it plays a ...
Karakus Akan A a Ondokuz Mayıs University School of Medicine , Department of Medical Education , Ondokuz Mayıs Samsun , - - 2014
Objectives: Under existing Turkish Road Traffic Law, there are two different blood alcohol concentration (BAC) limits allowed for drivers in 2013: zero blood alcohol and ≤0.50 g/L. All public transport, taxi, commercial and official vehicle drivers must maintain a zero blood alcohol concentration level while driving in the traffic. Private vehicle ...
Kerr A R AR Assistant Professor, Department of Implant Dentistry & Periodontics; Assistant Director, Bluestone Center for Clinical Research, New York University College of Dentistry, New York, NY, USA. Electronic address: - - 2015
To compare measures of dry mouth following extended use of an alcohol-based mouthrinse (LISTERINE Antiseptic [LA]) and a non-alcohol-based mouthrinse (Crest Pro-Health Rinse [CPH]) on healthy adults with "normal" salivary flow. This single-site, randomized, observer-blinded, parallel study compared unstimulated whole salivary flow and perceived dryness following daily use at weeks ...
Lahti R A RA Department of Forensic Medicine, Hjelt Institute, University of Helsinki, Finland. Electronic address: - - 2014
In a large number of forensic autopsies (N=28,184) the concentrations of ethanol in femoral blood and bladder urine were determined and the urine-to-blood concentration ratios of ethanol were calculated. Based on the differences in ethanol concentration between urine and blood, the deaths were classified as having occurred during the absorptive, ...
Shah Sweta S Department of Microbiology & Infection Prevention, Kokilaben Dhirubhai Ambani Hospital and Research Institute, Mumbai, Maharashtra, - - 2014
A prospective study was undertaken to evaluate the use of 2% (w/v) alcoholic chlorhexidine gluconate (2% AlcCHG) in donor arm preparation, to monitor the contamination rate of blood products after the collection and to find incidence of transfusion associated bacteremia. Optimal skin antisepsis of the phlebotomy site is essential to ...
Wright Trista H - - 2013
Two deaths involving 3, 4-methylenedioxypyrovalerone (MDPV) are reported. MDPV is a synthetic cathinone stimulant found in "bath salts" with neurological and cardiovascular toxicity. Biological specimens were analyzed for MDPV by GC/MS and LC/MS. A White man was found dead with signs of nausea and vomiting after repeatedly abusing bath salts ...
Liu Kuan-Liang - - 2013
Experimental evidence revealed that the performance of nanopore-based biosensing devices can be improved by applying a salt concentration gradient. To provide a theoretical explanation for this observation and explore the mechanisms involved, we model the capillary osmosis (or diffusioosmosis) in a charged solid-state nanopore connecting two large reservoirs. The effects ...
Fernando M Rohan - - 2012
OBJECTIVE: To investigate whether a new blood collection device stabilizes cell-free RNA (cfRNA) in blood post-phlebotomy when compared to collection using K(3)EDTA tubes. Design and Methods Blood samples were drawn from healthy donors into K(3)EDTA tubes and Cell-Free RNA BCTs (BCTs) and stored at room temperature (20-25°C). At specified time ...
Xin Nian - - 2012
Dragon's blood is a bright red resin obtained from Dracaena cochinchinensis. It is a traditional medicinal that is used for wound healing and to stop bleeding. Its main biological activity appears to be from phenolic compounds found in Dragon's blood. In this study, the radioprotective effects of Dragon's blood were ...
Günther Kalle - - 2012
BACKGROUND: Although important improvements of downstream molecular in vitro diagnostics assays based on RNA from blood were made, the pre-analytical workflow is still poorly defined. METHODS: We performed a multicenter study within the EU-granted SPIDIA project to investigate blood collection and shipping influence on the following RNA quality parameters: yield, ...
Matsuzaki Masayo - - 2010
Despite their being good markers of oxidative stress for clinical use, little is known about ubiquinol-10 (reduced coenzyme Q10) and ubiquinone-10 (oxidized coenzyme Q10) levels in foetuses and their mothers. This study investigates oxidative stress in 10 healthy maternal venous, umbilical arterial and venous bloods after vaginal delivery by measuring ...
Flo K - - 2010
To establish longitudinal reference ranges for the umbilical vein (UV) diameter, velocities and volume blood flow (Q(uv)) at a free loop of the umbilical cord and estimate the UV spatial velocity profile at this site. This was a prospective study of 53 low-risk pregnancies. The UV diameter and blood flow ...
Brunelli R - - 2010
Magnetic resonance imaging requested for a potentially serious indication, provided a unique opportunity to explore the intervillous circulation of placentas from pregnancies complicated by Intra Uterine Growth Restriction (IUGR) and to compare them to normal cases. This allowed an innovative characterization of in vivo utero-placental blood flow, correlating a compromised ...
Tejada-Martínez Andrés E - - 2011
Umbilical artery Doppler velocimetry waveform notching has long been associated with umbilical cord abnormalities, such as distortion, torsion, and/or compression (i.e., constriction). The physical mechanism by which the notching occurs has not been elucidated. Flow velocity waveforms (FVWs) from two-dimensional pulsatile flows in a constricted channel approximating a compressed umbilical ...
Flo Kari - - 2010
OBJECTIVE: To explore the relation between total utero-placental (TQ(uta)) and feto-placental (Q(uv)) blood flows and establish longitudinal reference ranges for the TQ(uta)/Q(uv) ratio and the mean uterine artery and umbilical artery pulsatility (UtaPI/UAPI) and resistance index (UtaRI/UARI) ratios. DESIGN: Prospective longitudinal observational study. SETTING: University hospital in Norway. POPULATION: Fifty-three ...
Thakor Avnesh S AS Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, - - 2010
Inadequate umbilical blood flow leads to intrauterine growth restriction, a major killer in perinatal medicine today. Nitric oxide (NO) is important in the maintenance of umbilical blood flow, and antioxidants increase NO bioavailability. What remains unknown is whether antioxidants can increase umbilical blood flow. Melatonin participates in circadian, seasonal, and ...
Baschat Ahmet Alexander - - 2010
To examine effects of fetoscopic laser occlusion of placental vascular anastomoses on umbilical venous volume flow in twin-to-twin transfusion syndrome. Absolute umbilical venous volume flow, measured preoperatively and 48 hours after fetoscopic laser occlusion was related to Doppler studies, bladder filling in donors, and anastomoses. Among 45 patients, recipients had ...
Malinger Gustavo - - 2011
Objective.?To study the association between fetal middle cerebral artery (MCA) Doppler-flow velocity waveforms and the lateral cerebral ventricular width in fetuses diagnosed with unilateral or bilateral ventriculomegaly. Methods.?A prospective cohort evaluation of the association between Doppler-flow velocity indices of the MCA and ventricular width in singleton fetuses referred because of ...
Hasegawa J - - 2010
To investigate whether umbilical venous velocity and venous velocity pulsation are associated with umbilical vein diameter, umbilical ring diameter and umbilical cord coiling index at midgestation. Two hundred and eighty pregnant women were enrolled in the study at between 18 and 24 weeks of gestation. The diameter of the umbilical ...
Negrini Rômulo - - 2011
To analyze and compare the vascular flow in different parts of the placenta of normal pregnant women between 22 and 34 weeks of gestation through three-dimensional power Doppler ultrasonography (3D power Doppler) vascular indices. This is a cross-sectional study involving 55 normal pregnant women with gestational ages between 22 and 34 weeks. ...
Sehgal A - - 2011
Patent ductus arteriosus in extremely premature babies is associated with major neonatal morbidities, such as necrotizing enterocolitis and intraventricular hemorrhage. This may be attributable, at least in part, to systemic hypoperfusion secondary to ductal steal. A hemodynamically significant ductus arteriosus (HSDA) is known to be associated with altered systemic blood ...
Nyberg M K - - 2010
In humans, fetal breathing movements affect blood velocities in the umbilical vein and artery, but it is not known whether fetal respiratory activity is associated with increased fetal blood flow through the placenta. We therefore tested this hypothesis in the present study. One-hundred and ten women with low-risk singleton pregnancies ...
Cruz-Martinez Rogelio - - 2010
OBJECTIVE: The objective of this study was to compare the temporal sequence of fetal brain hemodynamic changes in near-term small-for-gestational-age fetuses as measured by spectral Doppler indices or by fractional moving blood volume. STUDY DESIGN: Cerebral tissue perfusion measured by fractional moving blood volume, cerebroplacental ratio, anterior cerebral artery, and ...
Rizzo Giuseppe - - 2010
OBJECTIVE: To establish reference intervals for fetal umbilical vein (UV) diameter, UV time averaged maximum velocity (TAMXV) and UV flow (UVBF) at 11 + 0 to 13 plus; 6 weeks of gestation and to determine the intraobserver reliability of these measurements. METHODS: We considered, in a cross-sectional study, 162 fetuses ...
de Mooij Yolanda M - - 2010
OBJECTIVE: We sought to assess blood flow in relation to jugular lymphatic distension in fetuses with increased and normal nuchal translucency (NT). STUDY DESIGN: In all, 72 fetuses with normal NT and 71 fetuses with NT >95th percentile were evaluated. NT size, jugular lymphatic sacs (JLS), jugular vein and ductus ...
Kasdaglis T - - 2010
OBJECTIVE: Placental growth factor (PlGF) is a potent angiogenic factor that impacts on early placental vascular development. It was our aim to clarify relationships between PlGF and first-trimester maternal/placental factors that are related to placental development. METHODS: Prospectively enrolled patients at 11-14 weeks' gestation had serum PlGF measurement by enzyme-linked ...
Matias A - - 2010
OBJECTIVES: A discrepancy in crown-rump length (CRL) and/or nuchal translucency thickness (NT) between monochorionic twins has been found to be associated with an increased risk of twin-twin transfusion syndrome (TTTS). As one of the most plausible mechanisms for increased NT is hemodynamic imbalance and cardiac dysfunction, indirectly manifested by abnormal ...
Hofstaetter C - - 2010
Objective. To examine venous blood flow velocity in different types of fetal hydrops and its value in the prediction of outcome of pregnancies. Methods. Venous Doppler sonography was performed in 100 hydropic fetuses from 15 to 37 weeks of gestation. Blood velocity was recorded in the right hepatic vein (HV), ...
McElhinney Doff B DB Department of Cardiology, Children's Hospital Boston, and Pediatrics, Harvard Medical School, Boston, MA, USA. - - 2010
Children with hypoplastic left heart syndrome (HLHS) are at risk for neurodevelopmental dysfunction; prenatal factors may play a role in this predilection. Cerebral blood flow profiles are abnormal in fetuses with HLHS, raising the possibility that cerebral hemodynamics in utero may be related to neurodevelopmental abnormalities. Prenatal aortic valvuloplasty for ...
El Behery Manal M - - 2011
To evaluate the effect of umbilical vein (UV) blood flow measured by color-directed pulsed-wave Doppler on perinatal outcome of fetuses with lean and/or hypocoiled umbilical cord after 24 weeks of gestation. Two hundred and forty-four women with singleton fetus after 24 weeks of gestation were studied. Umbilical cord area, umbilical vessel cross-sectional ...
Liu Jing - - 2010
To explore whether or not the umbilical blood levels of cytokines can be used to indicate the adverse outcomes of hypoxic-ischemic encephalopathy (HIE) patients. Umbilical artery blood and peripheral venous blood samples were collected on the 1st, 3rd and 7th days after birth to detect the levels of IL-1 beta, ...
Hernandez-Andrade E - - 2009
OBJECTIVES: To evaluate the predictive value for perinatal death of the myocardial performance index (MPI) and aortic isthmus flow index (IFI), as isolated parameters and in a combined model including currently used Doppler indices, in preterm growth restricted (IUGR) fetuses. METHODS: Umbilical artery, fetal middle cerebral artery (MCA) and ductus ...
Miller Suzanne L - - 2009
OBJECTIVE: The objective was to characterize the effect of glucocorticoid treatment on fetal organ blood flow and regional cerebral blood flow in normally grown fetuses and fetuses with intrauterine fetal growth restriction (IUGR). STUDY DESIGN: Studies were undertaken in both control and IUGR fetal sheep; growth restriction was induced by ...
Ngan Kee Warwick D - - 2009
BACKGROUND: Use of ephedrine in obstetric patients is associated with depression of fetal acid-base status. The authors hypothesized that the mechanism underlying this is transfer of ephedrine across the placenta and stimulation of metabolism in the fetus. METHODS: A total of 104 women having elective Cesarean delivery under spinal anesthesia ...
Flo K - - 2009
OBJECTIVE: The umbilical vein (UV) is a single vessel and theoretically the volume of blood flowing through it should be equal whether it is measured at the intra-abdominal portion (IA) or a free loop of the umbilical cord (FL). However, the reported values vary considerably depending on the technique and ...
Cruz-Martinez Rogelio - - 2009
OBJECTIVE: The purpose of this study was to evaluate changes in cerebral blood perfusion and middle cerebral artery (MCA) Doppler in full-term small-for-gestational-age fetuses (SGA) and to explore their association with neonatal neurobehavioral performance. STUDY DESIGN: Frontal brain perfusion that was measured by fractional moving blood volume (FMBV) and MCA ...
Nomura Roseli Mieko Yamamoto - - 2009
OBJECTIVES: The aim of this study was to determine the correlation between ductus venosus (DV) Doppler velocimetry and fetal cardiac troponin T (cTnT). STUDY DESIGN: Between March 2007 and March 2008, 89 high-risk pregnancies were prospectively studied. All patients delivered by cesarean section and the Doppler exams were performed on ...
Rizzo Giuseppe - - 2009
Objective. To establish reference intervals for fetal umbilical vein (UV) diameter, UV time averaged maximum velocity (TAMXV) and UV flow (UVBF) at 11 + 0 to 13 plus; 6 weeks of gestation and to determine the intraobserver reliability of these measurements. Methods. We considered, in a cross-sectional study, 162 fetuses ...
Bartha Jose L - - 2009
The objective of the present study was to evaluate fetal cerebral circulation by using three-dimensional (3D) power Doppler ultrasound in normal and growth-restricted fetuses. A total of 100 normal grown fetuses were compared with other 25 with growth restriction (FGR). Three-dimensional power Doppler ultrasound was used to assess fetal cerebral ...
Aoekkasit Orapun - - 2009
OBJECTIVE: To investigate the flow of normal fetal pericardial fluid (PF) with increasing gestational age using Doppler velocimetry. METHOD: Ninety-five fetuses between 18 and 37 weeks of gestation with PF within the normal range were studied. PF was measured in 4-chamber view using M-mode or real-time ultrasound. Color Doppler was ...
White Pam - - 2009
A 7-month-old female, spayed border collie was referred to the Ontario Veterinary College due to a continuous murmur noted by the referring veterinarian prior to ovariohysterectomy. Auscultation confirmed a grade VI/VI continuous murmur. An echocardiogram confirmed patent ductus arteriosus (PDA). An Amplatz canine ductal occluder device was successfully placed for ...
Vimpeli T - - 2009
OBJECTIVES: To measure serial changes in cardiac output (CO) and its fraction distributed to the placenta at 11-20 weeks of gestation. METHODS: Blood flow velocities, and diameters of the aorta, pulmonary artery and umbilical vein, were measured longitudinally in 143 fetuses using pulsed-wave Doppler and two-dimensional ultrasound examination. RESULTS: Volume ...
Robertson Marcus C - - 2009
OBJECTIVE: To investigate whether persistently absent umbilical artery end-diastolic flow in the intrauterine growth-restricted fetus after betamethasone administration is associated with altered perinatal outcomes. METHODS: This is a retrospective cohort study of 92 pregnancies complicated by intrauterine growth restriction (IUGR) and absent end-diastolic flow in which antenatal betamethasone was given. ...
Spellacy William N - - 2009
OBJECTIVE: To determine the correlation of histological chorioamnionitis (CA) with and without clinical CA with umbilical cord blood gases, erythropoietin (EPO), and interleukin-6 (IL-6) levels. METHODS: Umbilical artery blood gas analysis (pH, pO(2), pCO(2), BE) and umbilical vein EPO and IL-6 levels were measured in 202 infants from normal, histological, ...
Acharya Ganesh - - 2009
OBJECTIVE: To measure oxygen uptake of term human fetuses and compare the values between those delivered vaginally following normal labor and those delivered by cesarean section before the onset of labor. DESIGN: This was a prospective cross-sectional study. SETTING: University teaching hospital. SAMPLE: Twenty healthy pregnant women at term (38-42 ...
Figueras F - - 2009
OBJECTIVES: To explore in growth-restricted fetuses the sequence of changes in aortic isthmus and ductus venosus blood flow in relation to other arterial Doppler parameters commonly used to evaluate fetal wellbeing. METHODS: Umbilical and middle cerebral arteries, ductus venosus and aortic isthmus were explored serially by means of pulsed Doppler ...
Guorong Lv - - 2009
OBJECTIVE: The aim of this study was to determine whether the type of congenital heart disease (CHD) or heart function influence fetal cerebrovascular blood flow dynamics. METHODS: Doppler flow velocimetry was performed in the umbilical artery (UA) and middle cerebral artery (MCA), and the ratio of the UA pulsatility index ...
Eixarch E - - 2008
OBJECTIVE: To assess the neurodevelopmental outcome at 2 years of age of children who had been small-for-gestational-age (SGA) term babies with cerebral blood flow redistribution. METHODS: Perinatal outcome was assessed in a cohort of 97 term singleton appropriate-for-gestational-age and 125 term singleton SGA fetuses with normal umbilical artery Doppler, stratified ...
Tchirikov M - - 2008
OBJECTIVES: To measure changes in cardiac output (CO) after partial cord occlusion in fetal sheep in order to investigate pathophysiological fetal adaptation mechanisms in a simulated acute placental insufficiency model under standardized conditions, with the aim of finding relevant methods for monitoring human fetuses during stress situations. METHODS: We used ...
Ebbing Cathrine C Department of Obsterics and Gynecology, Haukeland University Hospital, N-5021 Bergen, Norway. - - 2009
To establish longitudinal reference ranges for the fetal superior mesenteric artery (SMA) flow velocity and pulsatility index (PI(SMA)). Also to examine the hemodynamic relationship to venous liver perfusion and umbilical flow distribution in the liver, to other splanchnic arteries, and more generally to the middle cerebral and umbilical artery. Prospective ...
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