Search Results
Results 1 - 50 of 1446
1 2 3 4 5 6 7 8 9 10 >
Uždavinienė, Diana
For the first time to our knowledge the distribution of magnesium and calcium between blood plasma and blood cells in hepatitis C infected samples has been analyzed. The character of the distribution depends very much on the metal and the duration of the infection, suggesting that there is a variety ...
Orbegozo Cortés D D Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik 808, 1070 Brussels, - - 2014
/st>Several different crystalloid solutions are available for i.v. fluid administration but there is little information about their specific advantages and disadvantages. /st>We performed a systematic search of MEDLINE, EMBASE, and CENTRAL up until May 17, 2012, selecting all prospective human studies that directly compared any near-isotonic crystalloids and reported any ...
Erlandsen Erland J EJ Department of Clinical Biochemistry, Viborg Regional Hospital , Viborg , - - 2014
Objective. The purpose of this study in humans was to examine the influence of the gastrointestinal tract and liver on the serum concentrations of cystatin C. Methods. Eighteen healthy volunteers and 28 patients suspected of having chronic intestinal ischemia underwent catheterization of the abdominal aorta and the central hepatic vein. ...
Mohajeri G G Department of Animal Science, College of Abouraihan, University of Tehran, P.O. Box 11365-4117, Tehran, - - 2014
The present study examines blood metals levels and health parameters in dairy cows reared in areas around a Pb-Zn industrial complex located near the city of Zanjan-Iran. Blood samples (n = 27) were collected from cows reared around the smelter. Blood samples (n = 25) were also collected from cows reared in areas where ...
Chang Jae H JH - - 2014
Atorvastatin is eliminated by CYP3A4, which follows carrier-mediated uptake into hepatocytes by OATP1B1, OATP1B3 and OATP2B1. Multiple clinical studies demonstrated that OATP inhibition by rifampin had a greater impact on atorvastatin systemic concentration than itraconazole - mediated CYP3A4 inhibition. If it is assumed that the blood and hepatocyte compartments are ...
Ng Chaan S CS From the Departments of *Diagnostic Radiology, †Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; ‡CT Research, GE Healthcare, Waukesha, WI; Departments of §Gastrointestinal Medical Oncology, and ∥Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, - - 2014
The objective of this study was to assess the effects of pre-enhancement set point (T1) positioning on computed tomographic perfusion (CTp) parameter values. The CTp data from 16 patients with neuroendocrine liver metastases were analyzed with distributed parameter modeling to yield tissue blood flow (BF), blood volume, mean transit time, ...
Vliegenthart Adriaan D B AD 1 British Heart Foundation Centre for Cardiovascular Science, The Queen's Medical Research Institute, The University of Edinburgh , Edinburgh, United Kingdom - - 2014
Abstract Paracetamol is the commonest cause of acute liver failure in the Western world and biomarkers are needed that report early hepatotoxicity. The liver-enriched microRNA (miRNA), miR-122, is a promising biomarker currently being qualified in humans. For biomarker development and drug toxicity screening, the zebrafish has advantages over rodents; however, ...
Shyamala V V Research Diagnostics, Inc., Bengaluru, - - 2014
The aim of the study was to assess the blood safety in India through prevalence in thalassaemic population. Safety of the blood supply is a subject of great concern for all recipients. This review attempts to assess the relevance and format of tests for viruses in the context of transfusion ...
Kilpatrick S S Division of Veterinary Clinical Sciences, The Roslin Institute, Royal (Dick) School of Veterinary Studies, Hospital for Small Animals, The University of Edinburgh, Roslin, Midlothian EH25 - - 2014
Increased whole blood manganese concentrations have been reported in humans with primary liver disease. Due to the neurotoxic effects of manganese, altered manganese homeostasis has been linked to the development of hepatic encephalopathy. Whole blood manganese concentrations are increased in cases of canine congenital portosystemic shunts, but it remains unclear ...
Mikkelsen Kasper S KS Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Aarhus, - - 2014
The galactose analog 2-(18)F-fluoro-2-deoxy-d-galactose ((18)F-FDGal) is a suitable PET tracer for measuring hepatic galactokinase capacity in vivo, which provides estimates of hepatic metabolic function. As a result of a higher affinity of galactokinase toward galactose, the lumped constant (LC) for (18)F-FDGal was 0.13 in healthy subjects. The aim of the ...
Sugimoto Katsutoshi K Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan. Electronic address: - - 2014
The aim of this study was to assess quantitatively the Kupffer-phase enhancement patterns of hepatic hemangiomas in contrast-enhanced ultrasound (CEUS) with Sonazoid. A total of 46 patients with 46 hepatic hemangiomas (17.1 ± 6.2 mm in diameter, 34 typical type and 12 high-flow type) underwent CEUS in the Kupffer phase. The lesion-to-liver contrast ...
Lee Heun H Department of Occupational and Environmental Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 682-060, South - - 2014
We herein used data from the Korean National Health and Nutritional Examination Survey (KNHANES) 2008-2012 to examine the associations between blood mercury levels and subclinical changes of liver function in a representative sample of the adult Korean population. This study was based on data obtained from KNHANES, in which a ...
Cantrell Frank Lee FL California Poison Control System, San Diego Division, 200 West Arbor Drive, San Diego, 92103-8925, CA; Department of Clinical Pharmacy, University of California San Francisco, 521 Parnassus Avenue, San Francisco, 94117, - - 2014
Methylphenidate (MPD) is a widely prescribed stimulant used primarily for the treatment for attention-deficit/hyperactivity disorder (ADHD). Suicide attempts involving MPD ingestion have been well described; however, deaths attributed solely to MPD ingestion have not been reported. A 62-year-old woman was found dead on her floor. The only discrepancy in among ...
Ott Peter P Department of Hepatology and Gastroenterology, Aarhus University Hospital, 8000C, Aarhus, Denmark, - - 2014
Hyperammonemia is necessary for development of the cerebral complications to liver disease including hepatic encephalopathy and cerebral edema but the mechanisms are unclear. Ammonia is taken up by the brain in proportion to its arterial concentration. The flux into the brain is most likely by both diffusion of NH3 and ...
Paroskie Allison A Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, United - - 2014
Acute non-hemolytic transfusion reactions, consisting of both allergic and febrile reactions, are common occurring in up to 10.2% of transfused blood products [1], however anaphylaxis, or severe allergic reactions, are rare following transfusion. The incidence of anaphylaxis is more common after the transfusion of plasma containing products with estimations from ...
Rahbari N N NN Department of General, Visceral and Transplant - - 2014
Various devices have been developed to facilitate liver transection and reduce blood loss in liver resections. None of these has proven superiority compared with the classical clamp-crushing technique. This randomized clinical trial compared the effectiveness and safety of stapler transection with that of clamp-crushing during open liver resection. Patients admitted ...
Saitoh Wataru W Medicinal Safety Research Laboratories, Daiichi Sankyo Co., Ltd., - - 2014
To clarify the relationship between arginine metabolism and hepatic injury, metabolomic analysis was performed in rats treated with 3 representative hepatotoxicants, monocrotaline (MCT), concanavalin A (ConA), and α-naphthyl isothiocyanate (ANIT); or a myotoxicant, tetramethyl-p-phenylenediamine (TMPD). A single dose of MCT, ConA, or ANIT dose-dependently induced hepatocellular necrosis accompanied by decreased ...
Ara C C General Surgery Department, Inonu University School of Medicine, Malatya, - - 2014
Intraoperative blood loss and red blood cell transfusion requirements have a negative impact on outcome after orthotopic liver transplantation. In this study we compared blood transfusion requirements, bile duct injury, and dissection of hepatic artery rates in the patients with or without partial cholecystectomy during recipient hepatectomy. From December 2008 ...
Derbyshire Emily R ER Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, - - 2013
Drugs that target both malaria's liver and blood stages will be needed to reduce the disease's substantial worldwide morbidity and mortality. Evaluation of a 259-member library of compounds that block proliferation of the blood stage of malaria revealed several scaffolds - dihydroquinazolinones, phenyldiazenylpyridines, piperazinyl methyl quinolones, and bis-benzimidazoles - with ...
Nagengast Andrea K AK Department of Surgery, University of Louisville, Louisville, Kentucky, - - 2013
Total hepatic blood flow (HBF) via the hepatic artery and portal vein is highly dependent on gastrointestinal perfusion. During postprandial hyperemia, intestinal blood flow depends on nutrient composition, gastrointestinal location, and time. Immune-enhancing diets (IEDs) containing n-3 polyunsaturated fatty acids (PUFAs) selectively augment blood flow in the ileum at 60-120 ...
He Yong Y Malcom Randall VAMC, Gainesville, Fla; Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, College of Medicine, University of Florida, Gainesville, - - 2013
After vascular interventions, unidentified mechanisms disrupt the homeostasis of a focal narrowing to initiate an intimal thickening response. We hypothesize that perturbations in the hemodynamic microenvironment are the initiating event for this disruption of homeostasis and intimal thickening in vein bypass grafts. The objective of this study was to investigate ...
Wang Yinghuan Y Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, - - 2014
Benalaxyl as a xylem-systemic fungicide is usually direct sprayed on the soil surface, which is potential harm to the animals lived in the soil. However, the stereoselectivity of benalaxyl in reptiles have rarely been studied. In this study, Chinese lizards (Eremias argus) were firstly used to evaluate the stereoselectivity in ...
Hao Xue-Jia - - 2013
Assessment of tumor response after argon-helium cryoablation is critical in guiding future therapy for unresectable hepatocellular carcinoma. This study aimed to evaluate liver hemodynamics in hepatocellular carcinoma after argon-helium cryoablation with computed tomography perfusion. The control group comprised 40 volunteers without liver disease. The experimental group was composed of 15 ...
Cucchetti A - - 2013
Background: The possibility of outlining a risk profile for perioperative blood transfusion of cirrhotic patients submitted to hepatic resection can help to rationalize transfusion policy. Methods: Data from 323 hepatic resections, performed in cirrhotic patients, were reviewed. Bootstrap and a leave-one-out logistic regressions were applied to test the accuracy of ...
Alvarez J - - 2013
Liver dysfunction due to a low cardiac output state after cardiac surgery is associated with a poor prognosis, but whether one inotrope is superior to another in improving hepatic perfusion remains uncertain. This study compared the systemic and hepatic haemodynamic effects of levosimendan to dobutamine in patients with a low ...
Baig Mukhtiar M Mukhtiar Baig, PhD, Professor in Clinical Biochemistry, Faculty of Medicine Rabigh, King Abdulaziz University, Jeddah, Kingdom of Saudi - - 2013
Objective: To determine the knowledge, misconceptions and motivations towards blood donation among university students in KSA. Methods: This cross sectional study was carried out at the King Abdulaziz University, Rabigh campus, Jeddah, KSA. A total of 326 adult males were interviewed and each individual completed a questionnaire in Arabic language ...
Noiret L - - 2013
Hyperammonaemia is a common complication of chronic liver failure. Two main factors are thought to underlie this complication: a loss of hepatic detoxification function and the development of portosystemic shunting. However few studies have tried to quantify the importance of portosystemic shunting. Here we used a theoretical approach to test ...
Taouli Bachir - - 2013
OBJECTIVE. The objective of our study was to report our initial experience with dynamic contrast-enhanced MRI (DCE-MRI) for perfusion quantification of hepatocellular carcinoma (HCC) and surrounding liver. SUBJECTS AND METHODS. DCE-MRI of the liver was prospectively performed on 31 patients with HCC (male-female ratio, 26:5; mean age, 61 years; age ...
Putchakayala Krishna - - 2013
Despite increased use of acute hemodilution (AH) to reduce perioperative blood transfusion in patients undergoing partial hepatectomy, there is a lack of data on safety in those with comorbid medical illness. We performed a retrospective review of 96 patients undergoing partial hepatectomy with AH and low central venous pressure (CVP) ...
Harimoto Norifumi N Department of Surgery, Iizuka Hospital, Fukuoka, Japan. - - 2013
Stroke volume variation (SVV), which is measured by analyzing arterial blood pressure waveform characteristics, is a simple and sensitive indicator of fluid responsiveness. The current retrospective study was to investigate SVV and central venous pressure (CVP) during hepatic resection under clamping of both the infrahepatic inferior vena cava (IVC) and ...
Shiba Hiroaki - - 2013
Background/Aims: Because recent studies have reported that allogenic blood transfusion exerts negative immunomodulatory effects, we tried decreasing the use of blood products in perioperative management of hepatic resection since 2003. We retrospectively assessed the changes in our blood transfusion policy on hepatic resection for hepatocellular carcinoma (HCC). Methodology:Subjects were 78 ...
Kaibori Masaki M Department of Surgery, Hirakata Hospital, Kansai Medical University, Hirakata, Osaka, Japan. Electronic address: - - 2013
Excessive intraoperative blood loss and the possible requirement for blood transfusion are major problems in hepatic resection for liver tumors. The decrease of blood loss is a goal in liver surgery, and several technical developments have been introduced for this purpose. The aim of this prospective randomized study was to ...
Stankovic Zoran - - 2013
To evaluate influence of variation in spatio-temporal resolution and scan-rescan reproducibility on three-dimensional (3D) visualization and quantification of arterial and portal venous (PV) liver hemodynamics at four-dimensional (4D) flow MRI. Scan-rescan reproducibility of 3D hemodynamic analysis of the liver was evaluated in 10 healthy volunteers using 4D flow MRI at ...
Chen Jin Hui - - 2013
The pharmacokinetics of diniconazole enantiomers in quail (Coturnix coturnix japonica) were investigated by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Quails were exposed to racemic diniconazole in capsule by oral at dose of 10 mg/kg (body weight). The maximal concentrations observed in blood, heart, liver, and kidney were 3.18, 11.35, 12.32, 15.03 ...
Li Mao-Qin - - 2013
We sought to study the clinical efficacy of various combined blood purification techniques in patients with non-viral acute liver failure complicated by multiple organ dysfunction syndrome (MODS). For this purpose, 19 patients diagnosed of mid- or late-stage liver failure with MODS score-4 were randomly divided into 3 treatment groups of ...
Sauter Alexander W - - 2013
The heterogeneity of splenic computed tomography (CT) attenuation is still not fully understood. A differentiation of these enhancement patterns and other conditions such as diffuse spleen infiltration can be challenging. To understand the underlying physiological mechanisms of flow heterogeneity in normal and cirrhosis patients by quantifying perfusion parameters such as ...
Tralhão José Guilherme - - 2013
To investigate the impact of selective hepatic artery clamping (SHAC) in hepatocellular function. Three groups of Wistar male rats were subjected to SHAC ischemia period of 60min: Group A continuous SHAC were subjected to SHAC ischemia period of 60min, Group B intermittent SHAC of 30min with 5min of reperfusion and ...
Ozmen Ozlem - - 2013
This study describes the parasites and related pathologic observations in the house sparrow (Passer domesticus). In total, 48 birds were examined and 41 sparrows were found to be infected with one or more endoparasites (85.4%). The most common parasites were liver trematodes identified as Brachydistomum microscelis and Brachydistomum gracupicae. In ...
Choi Seong-Soo - - 2013
The safety of healthy living donors undergoing hepatic resection for living-donor liver transplantation is of paramount concern. Although blood transfusions have been associated with morbidity and mortality after hepatectomy, there is limited information about the risk factors associated with blood transfusion in living liver donors. We retrospectively analyzed 2344 donors ...
Beethe Amy B - - 2013
A 10 year old, 25 kggirl, who was formerly a conjoined twin at the heart, diaphragm, liver, duodenum, bile ducts, and intestine, was admitted for a repeat liver, small bowel, pancreas, and kidneymultivisceral transplant after having intestinal and liver failure. Intraoperatively, the patient had excessive bleeding, coagulopathy, and acidosis.Pulse Cooximetrywas ...
Martins Yuri Chaves - - 2013
Despite the abundance of information on cerebral malaria (CM), the pathogenesis of this disease is not completely understood. At present, two nonexclusive dominant hypotheses exist to explain how the neurological syndrome manifests: the sequestration (or mechanical) hypothesis and the inflammatory hypothesis. The sequestration hypothesis states that sequestration of Plasmodium falciparum-parasitized ...
Greaves Alana K - - 2013
Perfluorooctane sulfonate (PFOS) is a globally distributed persistent organic pollutant that has been found to bioaccumulate and biomagnify in aquatic food webs. Although principally in its linear isomeric configuration, 21-35% of the PFOS manufactured via electrochemical fluorination is produced as a branched structural isomer. PFOS isomer patterns were investigated in ...
Yang Ying-Ying - - 2013
Antivascular endothelial growth factor receptor (VEGFR) agents improve hepatic fibrosis and portal hypertension in cirrhosis. Detail interactions among recruited/activated leucocytes, hepatic angiogenesis and fibrogenesis, splanchnic blood pooling, decreased hepatic veins to fluctuated splanchnic blood volume (hepatic venous dysregulation), portal hypertensive syndrome and ascites have never explored in cirrhosis. Our study ...
Maruyama Hitoshi - - 2013
The inferior mesenteric vein (IMV) is detected in more than 90% of computed tomography images. Little is known about the hemodynamic features of IMV as a collateral vessel in portal hypertension, or its effects in clinical presentation and outcome. We investigated the roles of the IMV in portal hemodynamics, clinical ...
Khatun M - - 2013
A minimally invasive biopsy technique was evaluated for udder tissue collection in dairy cows with Escherichia coli mastitis. Meanwhile, the effect of taking repeated liver and udder biopsies on the systemic and local acute phase response (APR) of the dairy cows was investigated during the disease. The cows were divided ...
Adouani B - - 2013
To calculate the hepatitis B surface antigen (HBsAg) reactive rate for 2011 blood donors (BD) across Morocco. In addition, to monitor the profile of donors bearing the HBsAg during 2000 and 2011, we calculated the percentage of the prevalence in both sexes, in different age groups and in first-time replacement ...
Xu Chenyu - - 2013
Hepatitis E virus (HEV) infection has become relevant to blood transfusion practice because isolated cases of blood transmission have been reported and because HEV has been found to cause chronic infection and severe liver disease in immunocompromised patients. We tested for immunoglobulin (Ig)G and IgM antibodies to the HEV and ...
Iimuro Yuji - - 2013
While portal hemodynamics largely affects the liver regeneration after partial hepatectomy, whether the remnant liver homogeneously regenerates is unclear, especially in humans. We hypothesized that change in flow distribution varies in each remnant portal branch after liver resection in humans and the liver consequently regenerates heterogeneously. Twenty-two patients who underwent ...
Moore Deana L - - 2013
Aflatoxin is a widely occurring and harmful mycotoxin produced by strains of Aspergillus spp. growing on vegetable matter. We investigated the concentration of aflatoxin needed to impair normal physiologic responses and induce acute morbidity and mortality in Northern Bobwhites (Colinus virginianus). Ten wild-caught adult bobwhites (five males and five females) ...
Arshad Freeha - - 2013
In patients with cirrhosis, the synthesis of coagulation factors can fall short, reflected by a prolonged prothrombin time. Although anticoagulants factors are decreased as well, blood loss during orthotopic liver transplantation can still be excessive. Blood loss during orthotopic liver transplantation is currently managed by transfusion of red blood cell ...
1 2 3 4 5 6 7 8 9 10 >