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Herbertson Luke H LH Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, - - 2014
Multilaboratory in vitro blood damage testing was performed on a simple nozzle model to determine how different flow parameters and blood properties affect device-induced hemolysis and to generate data for comparison with computational fluid dynamics-based predictions of blood damage as part of an FDA initiative for assessing medical device safety. ...
Jackups Ronald R Jr Department of Pathology & Immunology, Washington University School of Medicine, St Louis, - - 2014
Transfusion of ABO-incompatible platelets (PLTs) is associated with reduced PLT recovery and a risk of transfusion reactions. However, a policy of transfusing only ABO-identical PLTs may increase wastage due to product outdating. A prospective study attempting to compare the effects of different ABO compatibility strategies could be costly and disruptive ...
McNally Andrew A Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, Indiana - - - 2014
Arteriovenous graft patency is limited by terminal occlusion caused by intimal hyperplasia (IH). Motivated by evidence that flow disturbances promote IH progression, a modular anastomotic valve device (MAVD) was designed to isolate the graft from the circulation between dialysis periods (closed position) and enable vascular access during dialysis (open position). ...
Terada Yukinori Y Department of Neurosurgery, Tazuke Kofukai Medical Research Institute and Kitano Hospital; Osaka, Japan - - - 2014
Cerebral blood volume (CBV) can be measured using a C-arm flat detector angiographic system. The present report describes a case in which cerebral hyperperfusion was detected with the Neuro parenchymal blood volume (PBV) system (syngo Neuro PBV IR, Siemens Medical Solutions, Erlangen, Germany) during carotid artery stenting (CAS). An 89-year-old ...
Gould Bronwen B From the Division of Neurology (B.G., R.M., L.C.G., M.K., T.J., A.S., K.B.) and Department of Diagnostic Imaging (D.E.), University of Alberta, Edmonton, Alberta, Canada; Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada (M.D.H., S.B.C., A.M.D.); Division of Neurology, University of British Columbia, Vancouver, British Columbia, Canada (N.A.); and Division of Neurology, University of British Columbia, Ottawa, Ontario, Canada - - 2014
The Intracerebral Hemorrhage Acutely Decreasing Arterial Pressure Trial (ICH ADAPT) demonstrated blood pressure (BP) reduction does not affect mean perihematoma or hemispheric cerebral blood flow. Nonetheless, portions of the perihematoma and borderzones may reach ischemic thresholds after BP reduction. We tested the hypothesis that BP reduction after intracerebral hemorrhage results ...
Wu Yue - - 2014
Turbulent flows inherently feature 3D spatial structures and temporal dynamics. As a result, 4D experimental techniques have been long desired to fully resolve turbulent flows in all three spatial directions and time. This work describes the demonstration of such 4D measurements in two-phase flows using computed tomography and Mie scattering. ...
Tsai Chyong-Ying CY School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan (Tsai, LC Wang)Taipei Zoo, Taipei, Taiwan (Yu), National Chung Hsing University, Taichung, Taiwan (YW Wang)National Chiayi University, Chiayi City, Taiwan (Fan, - - 2014
Various staining methods are available for reptilian species blood cell quantification. However, these methods have shown inaccurate differentiation limitations. The current study evaluates staining effects and blood cell counting results using an alternative method, counting blood cells diluted with 0.45% sodium chloride solution and stained with crystal violet. Blood samples ...
Terao Junji J Department of Food Science, Institute of Health Biosciences, University of Tokushima Graduate School, Kuramoto3-18-15 Tokushima 770-8503 Japan. Electronic address: - - 2014
Prenylflavonoids are distributed widely in the plant kingdom and have attracted appreciable attention because of their potential benefits for human health. Prenylation may be a promising tool for applying the biological functions of flavonoids to clinical uses. The bioavailability and bioaccumulation of prenylflavonoids have not been clarified, but extensive studies ...
Prodanovic Srdjan S Dept. of Mech. Eng., Univ. of Rochester, 383 Quinby Rd., Rochester, NY 14623, - - 2014
The mechano-transduction of the mammalian cochlea occurs in the micro-fluid domain between the tectorial membrane and the reticular lamina called the subtectorial space. The subtectorial fluid bathes the bundled stereocilia of the inner hair cells (IHCs). These cells are responsible for the onset of neural impulses in the auditory nerve ...
Cheuvront Samuel N SN U.S. Army Research Institute of Environmental Medicine, Natick, - - 2014
Substituting whole blood osmolality for plasma osmolality could expedite treatments otherwise delayed by the time required to separate erythrocytes from plasma. The purpose of this study was to compare the measured osmolality (mmol/kg) and calculated osmolarity (mmol/l) of whole blood and plasma. The osmolality of whole blood and plasma was ...
Baliarsingh S - - 2014
Potassium levels in stored blood bags increases as they age. Hyperkalemia in transfused blood has undesirable cardiac effects. Within a 19-month period, baseline and weekly samples from 15 CPDA-1 whole blood bags were collected till 28 days of storage and analysed for potassium, sodium, uric acid, albumin and whole blood haemoglobin. ...
Burgess W Patrick WP MD Scientific, LLC, 1214 Wareham Court, Charlotte, NC 28207, - - 2014
Nephropathy following contrast media (CM) exposure is reduced by administration before, during, and after the contrast procedure of either isotonic sodium chloride solution (Saline) or isotonic sodium bicarbonate solution (IsoBicarb). The reasons for this reduction are not well established for either sodium salt; probable mechanisms are discussed in this paper. ...
Adriaens Antita A Department of Medicine and Clinical Biology of Small Animals, Faculty of Veterinary Medicine, Ghent University, Merelbeke, - - 2014
To gain insights into the working mechanism of morphine, regional cerebral blood flow (rCBF) patterns after morphine administration were assessed in dogs. In a randomized cross-over experimental study, rCBF was estimated with 99mTc-Ethylcysteinate Dimer single photon emission computed tomography in 8 dogs at baseline, at 30 minutes and at 120 ...
Kron Susanne - - 2013
Recording the relative blood volume is a standard feature of modern dialysis devices, enabling feedback guidance of ultrafiltration and dialysate conductivity. Technically, the process is based on optical or ultrasonic methods. On the grounds of clinical evidence suggesting a malfunction of the optical hemoglobin (Hb)-dependent absorbance method in the presence ...
Owen Bethan E - - 2013
To determine more conclusively whether intravenous (IV) administration of 3% saline is more efficacious than oral administration in reversing below normal blood sodium concentrations in runners with biochemical hyponatremia. Randomized controlled trial. 26 hyponatremic race finishers participating in the 161-km Western States Endurance Run were randomized to receive either an ...
Boulton F E - - 2013
The pioneers of transfusion medicine around the turn of the 19th into the 20th centuries struggled with the awkward propensity of shed blood to clot. This article, a companion to a previous one (Boulton, 2013, Submitted for publication), describes in more detail how they recognised a potential for chemical anticoagulants ...
Cleary Maureen - - 2013
Fluctuations in blood phenylalanine concentrations may be an important determinant of intellectual outcome in patients with early and continuously treated phenylketonuria (PKU). This review evaluates the studies on phenylalanine fluctuations, factors affecting fluctuations, and if stabilizing phenylalanine concentrations affects outcomes, particularly neurocognitive outcome. Electronic literature searches of Embase and PubMed ...
Birgisdottir B E - - 2013
The first aim of the study was to evaluate calculated dietary intake and concentrations measured in blood or urine of essential and toxic elements in relation to nutritional and toxicological reference values. The second aim was to identify patterns of the element concentrations in blood and urine and to identify ...
Zeng Rong - - 2013
Abstract Background: A national cross-sectional survey on the reporting of critical values was conducted to provide suggestions on monitoring of the quality indicator and obtain the goal of quality improvement. Methods: All clinical laboratories participating in the external quality assessment (EQA) programs of chemistry, blood gas, and hematology tests organized ...
Olson Jordan - - 2013
Storing packed red blood cells (pRBCs) increases the potassium concentration. This effect is characterized in citrate phosphate dextrose/citrate phosphate dextrose adenine units but not published for Adsol (AS-5) units. The change in whole-blood potassium concentration in pediatric patients during routine transfusion is also poorly characterized. In this study, pediatric patients ...
Black Katherine Elizabeth - - 2013
Blood sodium concentration of tetraplegics during exercise has not been investigated. This study aimed to measure blood sodium changes in relation to fluid intakes and thermal comfort in tetraplegics during wheelchair rugby training. Twelve international male wheelchair rugby players volunteered, and measures were taken during 2 training sessions. Body mass, ...
Xie Liangxia - - 2013
We proposed here a potassium selective optode incorporating NaYF(4):Er,Yb upconverting nanorods and chromoionophore ETH 5294 together in hydrophobic polymer matrixes and the response of the optode is based on changes in the upconverting luminescence intensity induced from the absorption change of the proton sensitive chromoionophore. The optode was used for ...
Buckley Erin M EM Division of Neurology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA. - - 2013
Sodium bicarbonate (NaHCO3) is a common treatment for metabolic acidemia; however, little definitive information exists regarding its treatment efficacy and cerebral hemodynamic effects. This pilot observational study quantifies relative changes in cerebral blood flow (ΔrCBF) and oxy- and deoxyhemoglobin concentrations (ΔHbO2 and ΔHb) due to bolus administration of NaHCO3 in ...
Ren Rendong - - 2013
Laminaria japonica is traditionally eaten in Japan as a beneficial food for thrombosis. The alga contains two specific ingredients, a xanthophyll fucoxanthin (FX) and a polysaccharide, F-fucoidan (FD). The aim of the present study was to investigate whether FX or FD exhibited anti-thrombotic effects. For this purpose, three types of ...
Leung Anne Kit-Hung - - 2013
Background. The emergence of a commercially prepared citrate solution has revolutionized the use of RCA in the intensive care unit (ICU). The aim of this study was to evaluate the safety profile of a commercially prepared citrate solution. Method. Predilution continuous venovenous hemofiltration (CVVH) was performed using Prismocitrate 10/2 at ...
Woodhams Reiko - - 2013
To evaluate the feasibility and usefulness of imipenem/cilastatin sodium (IPM/CS) as an embolic agent for intestinal bleeding from neoplasms. Seven patients who underwent 11 transarterial embolisations (TAEs) using IPM/CS as an embolic material for duodenal or small/large intestinal tumour bleeding from January 2004 to December 2011 were retrospectively evaluated. A ...
Fallahi L L MSc of Biochemistry, Payam nor University, Taft, Yazd, - - 2013
Blood transfusion is associated with side effects caused by residual leukocytes in blood and blood components. Using leukodepleted blood components can decrease some of these adverse effects. Among the various methods to remove leukocytes in blood components, prestorage leukoreduction has been most efficient, but the evidence of clinical side effects ...
Sousa Rejane S - - 2012
BACKGROUND: The economic consequences from mortality of sheep after blood loss can be considerable. To date there are no reports addressing hematologic, blood gas, and biochemical changes in ovine blood stored in CPDA-1 bags. OBJECTIVES: The aim of this study was to investigate hematologic, blood gas, and biochemical alterations resulting ...
Tvermoes Brooke E - - 2012
Recently, there has been an increase in the marketing and sales of dietary supplements, energy drinks, and other consumer products that may contain relatively high concentrations of essential elements. Cobalt-containing supplements are readily available in the U.S. and have been marketed to consumers as energy enhancers. However, little information is ...
Black Katherine Elizabeth KE a Department of Human Nutrition , University of Otago , Dunedin , New - - 2014
Abstract Current hydration guidelines are designed to address the fine balance between minimising dehydration while reducing the risk of hyponatremia. During prolonged cycling events small discrepancies between drinking behaviour and fluid requirements may be detrimental to health and performance. The present study aimed to investigate the hydration practices of competitors ...
Pichiorri Floriana - - 2012
Objectives- To determine whether intermittent theta burst stimulation influences cerebral hemodynamics, we investigated changes induced by intermittent theta burst stimulation on the middle cerebral artery cerebral blood flow velocity and vasomotor reactivity to carbon dioxide (CO(2)) in healthy participants. The middle cerebral artery flow velocity and vasomotor reactivity were monitored ...
Kindler Jochen - - 2012
BACKGROUND: Transcranial magnetic stimulation (TMS) is a novel therapeutic approach, used in patients with pharmacoresistant auditory verbal hallucinations (AVH). To investigate the neurobiological effects of TMS on AVH, we measured cerebral blood flow with pseudo-continuous magnetic resonance-arterial spin labeling 20 ± 6 hours before and after TMS treatment. METHODS: Thirty ...
Catena Emanuele - - 2012
BACKGROUND: Hypothermia in combination with selective cerebral perfusion is a well-documented technique for cerebral protection during aortic arch surgery. However, such complex surgery is still accompanied by a considerable incidence of neurological events. AIM: This study describes the advantages of transcranial color Doppler ultrasound (TCDU) as a noninvasive real-time method ...
Ravelet F - - 2012
We provide experimental and numerical evidence of in-blades vortices in the von Kármán swirling flow. We estimate the associated kinematic α-effect tensor and show that it is compatible with recent models of the von Kármán sodium (VKS) dynamo. We further show that depending on the relative frequency of the two impellers, the ...
Staikou C - - 2012
Laparoscopic surgery is possibly associated with a risk of intracranial pressure (ICP) increase due to pneumoperitoneum in patients with ventriculoperitoneal shunts (VPS). Invasive techniques for shunt pressure monitoring are not routinely used because of the possible complications. Transcranial Doppler (TCD) is a non-invasive, safe method which gives accurate information about ...
Lopez Juan Carlos - - 2012
Severe lithium poisoning is a frequent condition in the intoxicated intensive care unit population. Dialysis is the treatment of choice, but no clinical markers predicting higher requirement for dialysis have been identified to date. We analyze the characteristics of lithium overdose patients needing dialysis to improve lithium clearance, and identify ...
Panerai Ronney B - - 2012
Neural activation induces changes in cerebral blood flow velocity (CBFV) with separate contributions from resistance-area product (V(RAP)) and critical closing pressure (V(CrCP)). We modelled the dependence of V(RAP) and V(CrCP) on arterial blood pressure (ABP), end-tidal CO(2)(EtCO(2)) and cognitive stimulation to test the hypothesis that VRAP reflects myogenic activity whilst ...
Satoh-Kuriwada Shizuko - - 2012
OBJECTIVE: Minor salivary gland flow rate (MF) has been proposed as a key feature of xerostomia (subjective feeling of dry mouth). To assess its diagnostic performance, MF was compared in xerostomia and control subjects. DESIGN: Sixty-six subjects with xerostomia and 30 controls were enrolled. MF was measured in the lower ...
Takahashi Shun - - 2012
The subgenual anterior cingulate cortex (Cg25) has been reported to be a node of mood-regulatory networks. Using a responder and a non-responder of repetitive transcranial magnetic stimulation (rTMS) for depression, we examined pre/post-treatment cerebral blood flow (CBF) in the Cg25 and treatment-related CBF changes in cortical/subcortical regions. In the responder, ...
Harty Niall J NJ Lahey Clinic, Burlington, MA 01805, - - 2012
What's known on the subject? and What does the study add? Lumagel™ is a reverse thermosensitive polymer (RTP) that has previously been described in the literature as providing temporary vascular occlusion to allow for bloodless partial nephrectomy (PN) while maintaining blood flow to the untargeted portion of the kidney. At ...
Schumacher Sarah N - - 2012
The objective of this study was to develop a simple, cost-effective method of HbF determination potentially useable in underdeveloped countries to determine sickle cell patient response to hydroxyurea treatment. Normal adult blood (HbA), cord blood (HbF), and a 50:50 mixture (HbA+F) were the three sample types used in procedure development. ...
Yamazaki Hajime - - 2012
Stellate ganglion block (SGB) is a widely used procedure for treatment of pain in the head and upper body, but the clinical signs used to verify the effectiveness of SGB can be ambiguous or variable in some patients. We observed the chronological changes in perfusion index (PI) from pulse oximetry ...
Hijikata W - - 2011
In the field of rotary blood pumps, contactless support of the impeller by a magnetic bearing has been identified as a promising method to reduce blood damage and enhance durability. The authors developed a two-degrees-of-freedom radial controlled magnetic bearing system without a permanent magnet in the impeller in order that ...
Lefrère Jean-Jacques - - 2011
Originally pasted on walls and on locations reserved specially for that purpose, the poster is a medium for advertising and promotion to be seen on the streets and in public places. More recently, it has spread, in a smaller format, on dedicated indoor sites: billboards, columns, street furniture, and so ...
Forner Lone L Department of Anaesthesia, Centre of Head and Orthopaedics, Copenhagen University Hospital, Blegdamsvej 9, DK-2100 Copenhagen Ø, Denmark. - - 2011
Irradiated head and neck cancer survivors treated in the Hyperbaric Oxygen (HBO) Unit, Copenhagen University Hospital, spontaneously reported improvement of radiation-induced dry mouth feeling. The aim of this pilot study was to evaluate salivary flow rate and xerostomia before and after HBO in irradiated head and neck cancer patients. Eighty ...
Borges Boniek Castillo Dutra - - 2011
The aim of this study was to evaluate the depth of curing of 10 contemporary blue light-activated dental flowable materials at several opacities, influenced by different irradiation times using FT-IR spectroscopy. Fifty-five specimens (n = 5) with a 5-mm diameter and 1-mm thickness of translucent (Opallis Flow T), yellowed (Master ...
Zarybnicka Lenka - - 2011
Purpose: The large white pig is a useful experimental model to compare in vivo, in vitro and ex vivo sensitivity of peripheral blood leukocytes to ionising radiation. Such studies are impossible to perform in humans and laboratory rodents due to ethical reasons and body size, respectively. We analysed dose- and time-dependent changes of ...
Schreiner Leonhard - - 2011
The function of phagocytic and antigen presenting cells is of crucial importance to sustain immune competence against infectious agents as well as malignancies. We here describe a reproducible procedure for the quantification of phagocytosis by leukocytes in whole blood. For this, a pH-sensitive green-fluorescent protein- (GFP) like dye (Eos-FP) is ...
Bak Jimmy - - 2011
We have demonstrated that it is possible to launch UVC LED light into bacterial contaminated polymer tubes/catheters and disinfect the intraluminal space of these tubes. This can be achieved by UVC treatment of the catheters on a regular basis. Catheters are in the distal end equipped with an exit hole ...
Sloan Steven R - - 2011
In addition to the issues concerning blood transfusions in general, special considerations apply to transfusing neonates. Young infants' plasma may contain maternal antibodies to ABO blood group antigens instead of the naturally occurring anti-ABO antibodies normally present in older patients. This facilitates the transplant of hearts across ABO boundaries but ...
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