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Zhang Jingwei J Department of Biomedical Engineering, Cornell University, Ithaca, NY, USA; Department of Radiology, Weill Cornell Medical College, New York, NY, - - 2014
To quantitatively map cerebral metabolic rate of oxygen ( CMRO2) and oxygen extraction fraction ( OEF) in human brains using quantitative susceptibility mapping (QSM) and arterial spin labeling-measured cerebral blood flow (CBF) before and after caffeine vasoconstriction. Using the multiecho, three-dimensional gradient echo sequence and an oral bolus of 200 ...
Henry E E The Women and Newborn's Clinical Program, Salt Lake City, UT, - - 2014
Objective:To compare neonatal red blood cell (RBC) transfusion rates in four large Intermountain Healthcare NICUs, all of which adhere to the same RBC transfusion guidelines.Study Design:This retrospective analysis was part of a transfusion-management quality-improvement project. De-identified data included RBC transfusions, clinical and laboratory findings, the anemia-prevention strategies in place in ...
Huang Shih-Han S SH Western University and London Health Sciences Centre, Department of Medicine, Nephrology Division, London, Ont., - - 2014
Background: It is important to know the relative clearances obtained when using single-needle versus double-needle cannulation techniques. Method: Twelve hemodialysis treatments were conducted using a machine that is capable of single-needle as well as double-needle cannulation. Single-needle and double-needle blood flow rates, as well as urea clearance, were compared. Results: ...
Huang Po-Hsun PH Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA. - - 2014
We present a programmable acoustofluidic pump that utilizes the acoustic streaming effects generated by the oscillation of tilted sharp-edge structures. This sharp-edge-based acoustofluidic pump is capable of generating stable flow rates as high as 8 μL min(-1) (~76 Pa of pumping pressure), and it can tune flow rates across a ...
Benyamine M M Laboratoire FIMAS, Université de Béchar, Boîte Postale 417, Béchar 08000, - - 2014
The discharge flow in a cylindrical and a rectangular silo using both monodisperse and bidisperse mixtures of spherical glass beads is studied experimentally. The flow rate is measured using a precision balance for a large range of particle diameters, size ratios, and outlet diameters. A simple physical model is proposed ...
Li Long L Department of Mechanical and Aerospace Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong - - 2014
We experimentally investigate the Poiseuille flows in nanochannels. It is found that the flow rate undergoes a transition between two linear regimes as the shear rate is varied. The transition indicates that the nonslip boundary condition is valid at low shear rate. When the shear rate is larger than a ...
Furman Matthew J MJ Division of Surgical Oncology, University of Massachusetts Medical Center, Worcester, - - 2014
Heated intraperitoneal chemotherapy (HIPEC) kills cancer cells via thermal injury and improved chemotherapeutic cytotoxicity. We hypothesize that higher HIPEC flow rates improve peritoneal heating and HIPEC efficacy. (1) A HIPEC-model (30.8 L cooler with attached extracorporeal pump) was filled with 37°C water containing a suspended 1 L saline bag (SB) wrapped in ...
Norquay Graham G Unit of Academic Radiology, Department of Cardiovascular Science, University of Sheffield, Sheffield, South Yorkshire, - - 2014
(129) Xe-blood NMR was performed over the full blood oxygenation range to evaluate (129) Xe relaxation and exchange dynamics in human blood. Hyperpolarized (129) Xe was equilibrated with blood and isolated plasma, and NMR was performed at 1.5 T. The (129) Xe relaxation rate was found to increase nonlinearly with ...
Kasraian Leila L Blood Transfusion Research Center, High Institute for Transfusion Research and Education, Shiraz, - - 2014
Knowledge of the reasons for donor deferral can help in planning more efficient recruitment strategies and evaluating donor selection criteria. This study aimed to investigate the rates and reasons for donor deferral. Retrospective study at Shiraz Blood Transfusion Center, Shiraz, Iran. 141,820 volunteers were interviewed confidentially by physicians before blood ...
Kim Seong Cheon SC a Department of Environmental Engineering , Chosun University , #375, Seosuk-dong, dong-gu, Gwang-ju 501-729 , Republic of - - 2014
A gliding arc plasma reactor was designed to destruct carbon dioxide (CO2), which is a major greenhouse gas. To increase the CO2 destruction rate with a high processing gas volume, an orifice baffle for gathering the gas flow at the centre of the electrodes was installed in the gliding arc ...
Lakkundi Anil A Neonatal Intensive Care Unit, John Hunter Children's Hospital, Newcastle NSW, Australia; University of Newcastle, Newcastle, - - 2014
Early respiratory management of very low birth weight infants has changed over recent years to a practice of early use of CPAP with early selective surfactant administration, and decreased use of mechanical ventilation. One strategy is to use the combination of surfactant and prompt extubation to nasal continuous positive airway ...
Perge Christophe C École Normale Supérieure de Lyon, Laboratoire de Physique, 46 allée d'Italie, 69364, Lyon cedex 07, - - 2014
Complex fluids such as emulsions, colloidal gels, polymer or surfactant solutions are all characterized by the existence of a "microstructure" which may couple to an external flow on time scales that are easily probed in experiments. Such a coupling between flow and microstructure usually leads to instabilities under relatively weak ...
Schmitz Kelly M KM 1  Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California 95616, - - 2014
Abstract From June to October 2010, 48 endangered riparian brush rabbits (Sylvilagus bachmani riparius) were trapped at a captive propagation site in central California with the intention of release into re-established habitats. During prerelease examinations, ticks and blood samples were collected for surveillance for Rickettsia spp., Anaplasma phagocytophilum, Borrelia burgdorferi, ...
Elawady Sanaa S From the Departments of *Clinical Pathology, †Medical Microbiology and Immunology, and ‡Paediatrics, Cairo University, and Ahmed Maher Teaching Hospital, Cairo, - - 2014
Sepsis in neonates hospitalized in the neonatal intensive care unit is a global problem and is a significant contributor to morbidity and mortality. Neutrophil surface CD64, the high-affinity Fc receptor, is quantitatively up-regulated during infection and sepsis. Our goal in this prospective study was to measure the neutrophil CD64 in ...
Djoufack-Momo Shelly M SM Department of Community Health, Wright State University, Dayton, Ohio, - - 2014
CO2 euthanasia is used widely for small laboratory animals, such as rodents. A common necessity in many animal research facilities is to euthanize mice in sequential batches. We assessed the effects of several variables on the time it took for CO2 to dissipate within a chamber. Using standard euthanasia time, ...
Song Wei W 1] Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA [2] Department of Physics, Harbin Institute of Technology, 92 West Da-Zhi Street Nangang District, Harbin, Heilongjiang 150080, China - - 2014
Quantitatively determining physiological parameters at a microscopic level in the retina furthers the understanding of the molecular pathways of blinding diseases, such as diabetic retinopathy and glaucoma. An essential parameter, which has yet to be quantified noninvasively, is the retinal oxygen metabolic rate (rMRO2). Quantifying rMRO2 is challenging because two ...
Czernik Christoph - - 2013
Alveolar--capillary membrane leaks can increase the amount of surfactant protein B (SP-B) in the bloodstream. The purpose of this study was to measure the concentration of C-proSP-B, a SP-B precursor that includes C-terminal domains, in various body fluids of newborn infants and determine its dependence on gestational age. C-pro-SPB was ...
Qu Guangbo - - 2013
Graphene oxide (GO) displays promising properties for biomedical applications including drug delivery and cancer therapeutics. However, GO exposure also raises safety concerns such as potential side effects on health. Here, the biological effects of GO suspended in phosphate buffered saline (PBS) with or without 1% nonionic surfactant Tween 80 were ...
Jugg B - - 2013
Context. Sulfur mustard is a blister agent that can cause death by pulmonary damage. There is currently no effective treatment. N-acetyl-L-cysteine (NAC) has mucolytic and antioxidant actions and is an important pre-cursor of cellular glutathione synthesis. These actions may have potential to reduce mustard-induced lung injury. Objective. Evaluate the effect ...
Atis Severine S Université Pierre et Marie Curie, 4 Place Jussieu, 75005 Paris, France and Université Paris-Sud, CNRS, Laboratoire FAST, Bâtiment 502, Campus Universitaire, Orsay F-91405, - - 2013
We analyze experimentally chemical wave propagation in the disordered flow field of a porous medium. The reaction fronts travel at a constant velocity that drastically depends on the mean flow direction and rate. The fronts may propagate either downstream and upstream but, surprisingly, they remain static over a range of ...
Fuchs H - - 2013
Background: Sustained lung inflations improve oxygenation but may impair hemodynamics. This study aimed to determine effects of short sustained inflations on cerebral blood flow and cerebral tissue oxygenation in experimental lung injury. Methods: Experiments were performed in 6 juvenile ventilated New Zealand white rabbits. The effects of a series of ...
Rey-Santano Carmen - - 2013
Background:Surfactant instillation may produce acute deleterious effects on gas exchange and both systemic and cerebral hemodynamics. Our aim was to compare the effects of aerosolized vs. bolus surfactant administration on gas exchange, lung mechanics, and cardiovascular function in premature lambs with respiratory distress syndrome (RDS).Methods:Fourteen preterm lambs (85% gestation) were ...
Bukiet F - - 2013
AIM: To assess the influence of concentration, temperature and surfactant addition to a sodium hypochlorite solution on its dynamic viscosity and to calculate the corresponding Reynolds number to determine the corresponding flow regimen. METHODOLOGY: The dynamic viscosity of the irrigant was assessed using a rotational viscometer. Sodium hypochlorite with concentrations ...
Kobayashi Ken K Laboratory of Dairy Food Science, Research Faculty of Agriculture, Hokkaido University, Sapporo, Japan. - - 2013
Mastitis, inflammation of the mammary gland, is the most costly common disease in the dairy industry, and is caused by mammary pathogenic bacteria, including Escherichia coli. The bacteria invade the mammary alveolar lumen and disrupt the blood-milk barrier. In normal mammary gland, alveolar epithelial tight junctions (TJs) contribute the blood-milk ...
Sempels Wouter W Department of Chemistry, KU Leuven, University of Leuven, Celestijnenlaan 200F, B-3001 Leuven, - - 2013
The deposition of material at the edge of evaporating droplets, known as the 'coffee ring effect', is caused by a radially outward capillary flow. This phenomenon is common to a wide array of systems including colloidal and bacterial systems. The role of surfactants in counteracting these coffee ring depositions is ...
Czynski Adam J AJ Department of Pediatrics, Division of Neonatology, Loma Linda University School of Medicine, Loma Linda, California, United States of - - 2013
Cerebral vessels in the premature newborn brain are well supplied with adrenergic nerves, stemming from the superior cervical ganglia (SCG), but their role in regulation of blood flow remains uncertain. To test this function twelve premature or two-week-old lambs were instrumented with laser Doppler flow probes in the parietal cortices ...
Christodoulopoulos G - - 2012
'Salivary abomasum disease' is a common syndrome in Greece affecting lambs and kids from three to 17 days of age. In this case series, we present clinical and laboratory findings from 37 affected lambs presented alive and subsequently euthanased for welfare reasons and necropsied, and also from 24 other lambs ...
Mussap Michele - - 2012
Soluble CD14 subtype (sCD14-ST), also named presepsin, is a 13 kDa truncated form of soluble CD14 (sCD14), consisting of 64 amino acid residues. Systemic inflammation and sepsis are characterized by an early, significant increase in sCD14-ST presepsin blood concentration and thus, this small polypeptide has been proposed as a novel, reliable ...
Aghajani Mahdi - - 2012
Artificial neural networks (ANNs) were used in this study to determine factors that control the polydispersity index (PDI) in an acetaminophen nanosuspension which was prepared using nanoprecipitation in microfluidic devices. The PDI of prepared formulations was measured by dynamic light scattering. Afterwards, the ANNs were applied to model the data. ...
Hernandez Jennifer S - - 2012
Objective To evaluate trends of emergency peripartum hysterectomy over two decades.Study Design This was a retrospective cohort study of peripartum hysterectomies at one institution from 1988 to 2009. Medical records were reviewed and data from the first 11 years were compared with data from the second 11 years.Results During the ...
Brearton C - - 2012
Cell salvage is increasingly used in the management of major obstetric haemorrhage. Its financial considerations were evaluated over a 5-year period. Cell salvage was introduced in the Liverpool Women's NHS Foundation Trust in 2006. Data were collected from all cases in which it was set-up and included the volume of ...
Wong K F - - 2012
OBJECTIVE. To review our experience in virtual blood banking for intra-operative transfusion in Hong Kong. DESIGN. Retrospective study. SETTING. Three major acute hospitals and a specialised centre for joint replacement surgery with installation of an Operating Theatre Blood Transaction System. PATIENTS. Patients undergoing surgery under anaesthesia and requiring intra-operative transfusion ...
Glasgow S M - - 2012
Mass casualty events (MCE) present health systems with a sudden demand on key services. The overall objective of this study was to describe the experience of the National Blood Service (NBS) following the largest UK MCE in recent times. Data was collated from the NBS database and directly from the ...
Joseph Julie T - - 2012
Babesiosis is usually acquired from a tick bite or through a blood transfusion. We report a case of babesiosis in an infant for whom vertical transmission was suggested by evidence of Babesia spp. antibodies in the heel-stick blood sample and confirmed by detection of Babesia spp. DNA in placenta tissue.
Carrie D W - - 2012
In many teleost fish, catecholamines activate a red blood cell (RBC) Na(+)/H(+) exchanger (βNHE), raising RBC intracellular pH to protect haemoglobin-O(2) loading. The present study tested the hypothesis that RBC intracellular carbonic anhydrase (CA) contributes to this adrenergic response. The pH of rainbow trout (Oncorhynchus mykiss) blood was monitored continuously ...
Finney Simon J - - 2012
ABSTRACT: In the previous issue of Critical Care, Vermeulen Windsant and colleagues demonstrate that transfusion of packed red cells is associated with a transient increase in plasma free haemoglobin and scavenging of nitric oxide in vitro. They also demonstrate that older units of blood have more free haemoglobin in their ...
Chung Kwang Hyo - - 2012
We present a novel blood filter unit that is designed to separate blood plasma from whole blood by simple magnetic actuation. A non-diluted blood sample is dropped into the filter unit and magnetic attraction is applied to squeeze out only blood plasma while blood particles are filtered by membranes stacked ...
Tinegate Hazel - - 2012
BACKGROUND: An understanding of current and changing patterns of red blood cell (RBC) use will help predict future demands and aid future planning for transfusion services. It can also highlight areas where efforts to optimize RBC use are most likely to be productive. STUDY DESIGN AND METHODS: Surveys were conducted ...
Sajwani F H - - 2012
A cross-match to transfused unit ratio of less than 2.0 is frequently used to assess performance in many hospital blood banks. This brief report was initiated to evaluate the practice at a local hospital and to emphasize the importance of regular educational sessions to improve blood transfusion practice. Retrospective data ...
Spidlen Josef - - 2012
FlowRepository.org is a Web-based flow cytometry data repository provided by the International Society for Advancement of Cytometry (ISAC). It supports storage, annotation, analysis, and sharing of flow cytometry datasets. A fundamental tenet of scientific research is that published results should be open to independent validation and refutation. With FlowRepository, researchers ...
Christensen Robert D - - 2012
Like many treatments available to small or ill neonates, erythrocyte transfusions carry both benefits and risks. This review examines recent publications aimed at better defining those benefits and those risks, as means of advancing evidence-based neonatal intensive care unit transfusion practices. Since decisions regarding whether to not to order an ...
Strandenes Geir - - 2012
BACKGROUND: Bleeding is a major cause of death in combat settings, and combat casualties in shock may benefit from fresh whole blood (FWB) transfusion. "Buddy transfusion" is a well-known lifesaving intervention, but little is known about donor combat safety aspects immediately after blood donation. The objectives of this study were ...
Francis Richard O RO Department of Pathology and Cell Biology, Columbia University Medical Center-New York Presbyterian Hospital, New York, New York 10032, USA. - - 2013
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is characterized by red blood cell (RBC) destruction in response to oxidative stress. Although blood donors are not routinely screened for G6PD deficiency, the transfusion of stored G6PD-deficient RBCs may have serious adverse outcomes. By measuring G6PD enzyme activity of RBC units from a large metropolitan ...
Massicotte Luc - - 2012
BACKGROUND: Orthotopic liver transplantation (OLT) has been associated with major blood loss and the need for blood product transfusions. During the last decade, improved surgical and anesthetic management has reduced intraoperative blood loss and blood product transfusions. A first report from our group published in 2005 described a mean intraoperative ...
McClain Colt M - - 2012
BACKGROUND: Quality indicators in transfusion medicine are necessary for patient safety and customer satisfaction. The turnaround time (TAT) of issuing red blood cells (RBCs) has emerged as a quality indicator but is not an established benchmark. We examined the TAT for issuing RBCs from the blood bank to the operating ...
Meny Geralyn M - - 2012
The American Rare Donor Program (ARDP), headquartered in Philadelphia, Pennsylvania, maintains a comprehensive database of donors with "rare blood types." The ARDP secures blood and blood products for difficult-to-transfuse patients. Remarkably, a significant number of physicians, both in the United States and abroad, remain unaware of the unique and critical ...
Jaime-Perez Jose C - - 2012
BACKGROUND: Umbilical cord blood (UCB) represents an alternative source of stem cells for transplantation for the treatment of hematologic malignancies and genetic disorders. There is scarce information detailing cord blood bank (CBB) collection and transplantation activities from developing countries. We documented our experience at a public university hospital in northeast ...
Geißler R Georg - - 2012
BACKGROUND: Demographic data illustrate clearly that people in highly developed countries get older, and the elderly need more blood transfusions than younger patients. Additionally, special extensive therapies result in an increased consumption of blood components. Beyond that the aging of the population reduces the total number of preferably young and ...
Young Carolyn - - 2012
BACKGROUND: Babesiosis is the most common transfusion-transmitted infection reported to the Food and Drug Administration (FDA). We developed and implemented the first laboratory-based blood donor screening program for Babesia microti to help reduce and prevent transfusion-transmitted babesiosis (TTB) and report results for the initial year. STUDY DESIGN AND METHODS: Selective ...
Tazi-Mokha A - - 2012
Objectives: We trace the history of blood donors and the recruitment strategies developed between 1988 and 2008 in the regional blood transfusion centre of Rabat. Beside, we draw a distribution map of the blood donors' population in Morocco during the year 2008. Background: Limited resource countries face considerable obstacles to ...
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