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Results 101 - 150 of 1233
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Makhlouf Michel - - 2013
Ultrasound use has become ubiquitous in pregnancy. We review the evidence regarding the benefits of routine ultrasound use during pregnancy. Routine ultrasound use before 24 weeks improves detection of undiagnosed twins, reduces postdates inductions, and allows detection of fetal anomalies before birth. Wide variations exist in the sensitivity of ultrasound ...
Giussani D A DA 1 Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, - - 2013
It is now recognized that the quality of the fetal environment during early development is important in programming cardiovascular health and disease in later life. Fetal hypoxia is one of the most common consequences of complicated pregnancies worldwide. However, in contrast to the extensive research effort on pregnancy affected by ...
Barrientos Gabriela - - 2013
BACKGROUNDAfter recognition of its pivotal contribution to fetomaternal tolerance, the study of galectin-1 (gal-1) functions in the context of pregnancy became an attractive topic in reproductive medicine. Despite considerable advances in the understanding of the immuno- and growth-regulatory properties of gal-1 at the fetal-maternal interface, many functional aspects of this ...
Hill Martin - - 2013
This is an EDITORIAL on SPECIAL ISSUE ON PREGNANCY AND STEROIDS:, This special issue of Journal of Steroid Biochemistry and Molecular Biology covers several topics, concerning the relevance of steroids in the physiology and pathophysiology of pregnancy.The studies, discussed herein provide better understanding the relevance of bioactive steroids in pregnancy, ...
Hasegawa Junichi - - 2013
To clarify whether openning of the uterine isthmus between 11 and 13weeks' gestation adversely affects the placental development. The uterine cervix and isthmus lengths were measured prospectively using transabdominal ultrasound at 11 to 13+6weeks' gestation. Following delivery, the pregnancy and delivery course were reviewed. The associations between the conditions of ...
Porciúncula Lisiane O - - 2013
Caffeine is certainly the psychostimulant substance most consumed worldwide. Over the past years, chronic consumption of caffeine has been associated with prevention of cognitive decline associated to aging and mnemonic deficits of brain disorders. While its preventive effects have been reported extensively, the cognitive enhancer properties of caffeine are relatively ...
Rich-Edwards Janet W - - 2013
Growing evidence indicates that women with a history of common pregnancy complications, including fetal growth restriction and preterm delivery (often combined as low birth weight), hypertensive disorders of pregnancy, and gestational diabetes, are at increased risk for cardiovascular disease later in life. The purpose of this paper was to review ...
Colmant Claire - - 2013
Early prenatal diagnosis of fetal sex is necessary to optimize pregnancy management in families known to be at risk of some heritable disorders. The demonstration of cell-free fetal DNA (cffDNA) in the mother's blood has made it possible to identify Y chromosome sequences in maternal blood and to determine fetal ...
Aparicio B - - 2013
Efforts aimed at improving pregnancy rates have focused on the search for additional markers of viability to supplement current criteria for embryo selection. Time-lapse technology represents a powerful tool in assisted reproduction for evaluating embryos dynamically. Whilst standard methods of embryo assessment are based on subjective morphology evaluation at discrete ...
Mogos Mulubrhan F - - 2013
This study aimed to review studies that addressed the impact of previous reproductive cancer diagnosis on selected fetal birth outcomes. We searched PubMed and Web of Knowledge to identify peer-reviewed articles published from January 1992 to December 2012, investigating the association between reproductive cancer and birth outcomes. After applying exclusion ...
- - 2013
We sought to review indications, technical aspects, risks, and recommendations for fetal blood sampling (FBS). A systematic review was performed using MEDLINE, PubMed, EMBASE, and Cochrane Library using the terms "fetal blood sampling," "percutaneous umbilical blood sampling," and "cordocentesis." The search was restricted to English-language articles published from 1966 through ...
Chen Qian - - 2013
Our aim was to describe the standard operating procedure for transcranial Doppler investigation of the ophthalmic artery in pregnancy, determine the interobserver and intraobserver variability using power M-mode technology, and review the existing literature. Accordingly, 27 healthy pregnant or immediately postpartum women were enrolled and underwent transcranial Doppler investigation of ...
Temel Sevilay - - 2013
Although the evidence for the associations between preconceptional risk factors and adverse pregnancy outcomes is extensive, the effectiveness of preconceptional interventions to reduce risk factors and to improve pregnancy outcomes remains partly unclear. The objective of this review is to summarize the available effectiveness of lifestyle interventions prior to pregnancy ...
Chen Chih-Ping - - 2013
We present rapid aneuploidy diagnosis of distal 9p deletion by array comparative genomic hybridization using uncultured amniocytes in a pregnancy associated with an abnormal maternal serum screening result and intrauterine growth restriction (IUGR) in the fetus. We review the literature of prenatal diagnosis of distal 9p deletion, and add abnormal ...
Haas Tara L - - 2013
Extensive vascular adaptations occur during pregnancy, and these result in the formation of a low resistance placental circulation that maintains high blood flow to the developing fetus. These adaptations encompass both functional and structural alterations, including altered vasoreactivity of resistance vessels, arterial remodeling and angiogenesis. This Special Topics Issue presents ...
Gizzo Salvatore - - 2013
This study aimed to identify the best management options in decision making in cases of cervicoisthmic and cesarean scar pregnancies and rare forms of ectopic pregnancies with high rates of pregnancy-related morbidity in the first trimester, more commonly associated with assisted reproductive medicine. We performed a literature review of the ...
Chevrier Jonathan J Center for Environmental Research and Children's Health, School of Public Health, University of California-Berkeley, 1995 University Avenue, Berkeley, CA 94720-7392, USA. - - 2013
Thyroid hormones play a fundamental role in fetal and child development. While iodine deficiency-related maternal and child hypothyroidism may cause severe mental retardation, recent evidence suggests that milder forms of maternal hypothyroidism and hypothyroxinemia during pregnancy are also associated with altered neurodevelopment. On the other hand, hyperthyroidism during pregnancy has ...
Liu Joseph - - 2013
Second-trimester tubal pregnancy is rarely encountered and published cases are limited. There are no established sonographic criteria to differentiate it from abdominal pregnancy; however, differences in their medical management make this distinction important. We report a case of a 14-week 5-day tubal pregnancy that presented near rupture. Sonography demonstrated many ...
Sienas Laura - - 2013
Objective: The objectives of this study were to survey the current research and provide an update on the uses and benefits of erythropoietin (EPO) in pregnancy and the postpartum period. Data Sources: A review of MEDLINE (1947 to present) was performed. Search terms included "erythropoietin," "pregnan*," with subheadings of "administration ...
Peck Jeremy W - - 2013
Pigmentary demarcation lines are common, especially in individuals with darker skin types. Type B pigmentary demarcation lines (Futcher lines) involve the posterior lower extremities and can be associated with pregnancy, often with spontaneous resolution after delivery. The pathogenesis of pigmentary demarcation lines remains unknown; however, neurogenic inflammation and/or mosaicism are ...
Tamblyn J A - - 2013
Villitis of unknown etiology (VUE) represents a common placental inflammatory lesion, primarily, but not exclusively, identifiable T lymphocytes at term. Despite considerable evidence to contest that this simply represents a benign pathological finding, VUE remains a significantly undervalued diagnosis. Given its association with adverse pregnancy outcomes; including fetal growth restriction, ...
Brennan Lesley J - - 2013
Preeclampsia is a multifaceted disorder of human pregnancy which affects millions of women worldwide (approximately 5% of all pregnancies) each year [reviewed in 129]. It is a leading cause of maternal morbidity and mortality, accounting for an estimated 50,000 deaths annually [reviewed in 40]. Preeclampsia is complex, affecting multiple systems, ...
Lautatzis Maria-Elena - - 2013
Metformin is an effective oral anti-hyperglycemic agent that is widely used to manage diabetes mellitus type 2 in the general population and more recently, in pregnancy. However, as metformin crosses the placenta, its use during pregnancy raises concerns regarding potential adverse effects on the mother and fetus. i) To provide ...
Wolf H T - - 2013
Today, pre-eclampsia (PE) is one of the leading causes of maternal and perinatal morbidity and mortality. It has been proposed that leisure time physical activity (LTPA) is associated with a decreased risk of PE. The objective of this study was to perform a systematic literature review examining the association between ...
Groenewoud Eva R - - 2013
BACKGROUNDFrozen-thawed embryo transfer (FET) enables surplus embryos derived from IVF or IVF-ICSI treatment to be stored and transferred at a later date. In recent years the number of FET cycles performed has increased due to transferring fewer embryos per transfer and improved laboratory techniques. Currently, there is little consensus on ...
de Aguiar M M - - 2013
The aim of this study was to systematically review the safety and efficacy of inhaled beclomethasone for asthma treatment in pregnant women. We performed a systematic review in Medline, LILACS and SciELO electronic databases in December 2012. A total of 3433 articles were found by using the keywords asthma, pregnancy ...
Brunet-Possenti F - - 2013
We report the observation of cutaneous Kaposi's sarcoma (KS) worsening during the second trimester of pregnancy in 2 African women. Both patients were tested seronegative for HIV. They had no complication during their pregnancy, and no evidence of extracutaneous disease was found, allowing therapeutic abstention. They gave birth to healthy ...
Hussein Brwa A - - 2013
May-Hegglin anomaly (MHA) is an autosomal dominant disorder, characterized by a variable degree of thrombocytopaenia, large platelets and inclusion bodies in white blood cells. Bleeding manifestations are generally mild, but severe bleeding episodes have been reported. This is a systematic review of literature for MHA during pregnancy. The review revealed ...
Iyoke C A - - 2013
Although ultrasonography was introduced into Obstetrics and Gynaecology by a British Gynaecologist over five decades ago, the requirements for formal training in its use by gynecologists in Nigeria is just beginning to catch on, despite its indispensible role in various aspects of our clinical practice. To describe the role of ...
Bajwa Sukhwinder Kaur SK Department of Obstetrics and Gynaecology, Gian Sagar Medical College and Hospital, Ram Nagar, Banur, Punjab, - - 2013
The gap between the developed and developing nations with regards to maternal mortality and morbidity may have narrowed but still a lot of dedicated work is required to bridge these differences. Obstetrical haemorrhage is the leading cause of maternal deaths in these developing nations especially in India. The most common ...
Webster Louise M - - 2013
Most recommended obstetric therapeutic agents are not licensed for their purpose. There is a lack of funding for research and little development of new therapeutic agents for use in the treatment of pregnancy-related disorders. Current therapeutics used in maternal health and their licensing status are reviewed and suggestions for these ...
Donoso Patricio - - 2013
Assisted reproductive techniques can lead to medical complications such as multiple pregnancy and ovarian hyperstimulation syndrome. A critical appraisal and strategies to reduce the occurrence of these complications are discussed in this manuscript.
Soyka Michael - - 2013
Pregnancy in opioid users poses a number of problems to treating physicians. Most guidelines recommend maintenance treatment to manage opioid addiction in pregnancy, with methadone being the gold standard. More recently, buprenorphine has been discussed as an alternate medication. The use and efficacy of buprenorphine in pregnancy is still controversial. ...
van der Pligt P - - 2013
Postpartum weight retention can predict future weight gain and long-term obesity. Moreover, failure to lose weight gained during pregnancy can lead to increased body mass index for subsequent pregnancies, increasing the risk of adverse maternal and foetal pregnancy outcomes. This systematic review evaluates the effectiveness of lifestyle interventions aimed at ...
Melse-Boonstra Alida - - 2013
Iodine deficiency affects an estimated 241 million school-aged children in the world. Little is known about iodine deficiency in relation to auditory function, except for the fact that deaf-mutism is one of the features of cretinism. In the present review, we documented the scientific knowledge on the role of iodine ...
Nishikawa Ai - - 2013
An increasing number of women with severe endometriosis have conceived through assisted reproductive technology, but endometriosis can cause life-threatening complications for both the mother and baby during pregnancy. We describe a case of endometriosis-induced spontaneous ileal perforation in pregnancy with massive intestinal haemorrhage that required caesarean section, right hemicolectomy and ...
Sesti Francesco - - 2013
The minimally invasive laparoscopic approach in the surgical treatment of diseases during pregnancy has become progressively more accepted and applied. In an attempt to overcome the potential adverse effects of pneumoperitoneum on the fetus, gasless laparoscopic surgery (GLS) has been developed. This article reviews the evidence available for the role ...
Bates Shannon M - - 2013
Approximately half of all pregnancy-related venous thromboembolic events are associated with thrombophilia. Although the most compelling data for a link between thrombophilia and other adverse pregnancy outcomes derive from women with antiphospholipid antibodies, some studies also suggest an association between these pregnancy complications and hereditary thrombophilias. Management of thrombophilia often ...
McCall Christina A - - 2013
"Therapeutic" bed rest continues to be used widely, despite evidence of no benefit and known harms. In this commentary, we summarize the Cochrane reviews of bed rest and propose an ethical argument for discontinuing this practice. Cochrane systematic reviews do not support "therapeutic" bed rest for threatened abortion, hypertension, preeclampsia, ...
Slattengren Andrew H - - 2013
When bleeding or pain occur in early pregnancy and ultrasound is inconclusive, a single progesterone test can often answer that question.
Park Tae Chul - - 2013
A woman in early pregnancy was referred due to severe pelvic pain. Vaginal examination showed a severely protruding left vaginal wall with severe tenderness. A transvaginal ultrasound showed a double uterus and a mixed echogenic mass next to the cervix of the left uterus. After creating an opening in the ...
Lane Barton F - - 2013
Vaginal bleeding is not uncommon in the first trimester of pregnancy. Ultrasound is the foremost modality for evaluating normal development of the gestational sac and embryo and for discriminating the causes of bleeding. While correlation with quantitative βHCG and clinical presentation is essential, sonographic criteria permit diagnosis of failed pregnancies, ...
Kasuga Yoshifumi - - 2013
During feto-placental development, chorion-amnion fusion occurs in early second trimester and persistent separation of the membranes beyond 17 weeks' gestation is considered abnormal (1). Several reports have shown that complete chorion-amnion separation, defined as the amnion being separated from the chorion on at least three sides of the gestational sac, ...
- - 2013
The care of the unborn child is of tremendous interest to many specialties, with anaesthesiology now gaining a distinct role as part of fetal multidisciplinary care. This book is an impressive collective effort of not less than 85 internationally renowned scientists and clinicians that compile their knowledge and expertise in ...
Johnson Chris - - 2013
There is growing recognition of the role that osteopathy can play in the treatment of women during pregnancy (King et al 2003; Sandler 1996; Green 2000). It is usual for the osteopathic training colleges to run a pregnancy clinic and give students the opportunity to focus on the particular changes ...
Mukherjee Soma - - 2013
Ludwig's angina is an infectious process involving submandibular, sublingual, and submental spaces that can rapidly progress to hemodynamic instability and airway obstruction. A 38-year-old unbooked multipara of low socioeconomic status with a poor oral and dental hygiene presented with bilateral submandibular cellulitis and intrauterine fetal demise. She delivered vaginally, and ...
Ferschl Marla M Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA, - - 2013
Recently published results suggest that prenatal repair of fetal myelomeningocele is a potentially preferable alternative when compared to postnatal repair. In this article, the pathology of myelomeningocele, unique physiologic considerations, perioperative anesthetic management, and ethical considerations of open fetal surgery for prenatal myelomeningocele repair are discussed. Open fetal surgeries have ...
Kattah Andrea G AG Department of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN 55905, - - 2013
Hypertensive pregnancy disorders complicate 6% to 8% of pregnancies and cause significant maternal and fetal morbidity and mortality. The goal of treatment is to prevent significant cerebrovascular and cardiovascular events in the mother without compromising fetal well-being. Current guidelines differentiate between the treatment of women with acute hypertensive syndromes of ...
Naljayan Mihran V MV Renal, Molecular, and Vascular Medicine Divisions, Department of Medicine, Beth Israel-Deaconess Medical Center, Harvard Medical School, Boston, MA, - - 2013
Preeclampsia affects 3% to 5% of all pregnancies and is a major cause of maternal and perinatal morbidity and mortality worldwide. This disorder is characterized by a constellation of signs and symptoms, most notably new-onset hypertension and proteinuria during the last trimester of pregnancy. In this review, the molecular mechanisms ...
Elzanaty Saad - - 2013
Ten to fifteen percent of infertile men are azoospermic, and sixty percent of these men have been classified as having non-obstructive azoospermia (NOA). NOA results from testicular failure, and one of the causes of this is the presence of varicocele. Varicocele is observed in 5-10 % of men with NOA. This ...
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