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Han Sileny N SN Gynecologic Oncology, University Hospitals Leuven, and Division of Oncology, KU Leuven, Herestraat 49, 3000, Leuven, Belgium, - - 2014
The diagnosis of a gynecological malignancy during pregnancy is rare but not uncommon. Cancer treatment during pregnancy is possible, but both maternal and fetal interests need to be respected. Different treatment plans may be justifiable and multidisciplinary treatment is advised. Clinical trials are virtually impossible, and current evidence is mainly ...
Martínez-Boví R R Departamento de Medicina y Cirugía Animal, Facultad de Veterinaria, Universidad CEU Cardenal Herrera, Alfara del Patriarca, - - 2014
The haemorrhagic anovulatory follicle (HAF) is the most common pathological anovulatory condition in the mare, but its cause remains unknown. An experimental model to induce luteinised unruptured follicles (LUF) with flunixin-meglumine (FM) has been developed. The LUF share similar morphological and hormonal characteristics with the HAF. To test the effect ...
Klein Jamie J Ben-Gurion University of the Negev, Soroka University Medical Center, Department of Obstetrics and Gynecology, Faculty of Health Sciences , POB 151, Beer Sheva 84101 , Israel - - 2014
Introduction: Gestational diabetes mellitus (GDM), defined as glucose intolerance with first recognition or onset during pregnancy, is steadily rising in prevalence. GDM affects ∼ 3 - 5% of pregnancies in the US and is associated with significant adverse perinatal and maternal outcomes. Diagnosing and treating GDM early in pregnancy is ...
Rac Martha W F MW University of Texas Southwestern Medical Center, Department of Obstetrics and - - 2014
 To construct a timeline for non-treponemal titer decline specific to pregnancy and evaluate factors associated with inadequate decline by delivery.  This was a retrospective chart review from September 1984 to June 2011 of women diagnosed with syphilis after 18 weeks of gestation. Women were treated according to stage of syphilis ...
Han Cha C Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, No. 154 Anshan Road, Heping District, Tianjin, 300052, People's Republic of - - 2014
Aerobic vaginitis (AV) is a newly defined clinical entity that is distinct from candidiasis, trichomoniasis and bacterial vaginosis (BV). Because of the poor recognition of AV, this condition can lead to treatment failures and is associated with severe complications, such as pelvic inflammatory disease, infertility, preterm birth and foetal infections. ...
Hiersch Liran L The Helen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, - - 2014
In the last three decades, systemic methotrexate (MTX) has become widely accepted as the primary treatment for unruptured tubal pregnancy. This has prompted investigations into the use of MTX in the management of interstitial pregnancy. To determine the effectiveness of methotrexate for treatment of interstitial pregnancy. We retrospectively reviewed 17 ...
van den Berg Joyce J Department of Obstetrics and Gynaecology, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands. Electronic address: - - 2014
Is treatment of early pregnancy failure (EPF) with sequential use of mifepristone and misoprostol more effective than treatment with misoprostol alone? In a retrospective cohort study at the Department of Obstetrics and Gynaecology of the Radboud University Medical Centre, 301 women with early pregnancy failure receiving medical treatment between January ...
Vadhera Rakesh B RB Department of Anesthesiology, University of Texas Medical Branch, Galveston, - - 2014
Hypertensive disorders of pregnancy complicate 7% to 10% of pregnancies and are among the major causes of maternal and perinatal morbidity and mortality. Recently American College of Obstetricians and Gynecologists Taskforce on Hypertension during Pregnancy modified the diagnosis and management of hypertension in pregnancy, recommending prompt diagnosis, admission, close monitoring, ...
Friedman E E Department of Animal Science, Faculty of Agriculture, Food and Environment, the Hebrew University, Rehovot 76100, - - 2014
Reduced conception rate (CR) during the hot summer and subsequent autumn is a well-documented phenomenon. Intensive use of cooling systems can improve summer and autumn reproductive performance, but is unable to increase CR to winter and spring levels. We examined whether combined hormonal treatments-to increase follicular turnover before artificial insemination ...
Murto Tiina T Department of Women's and Children's Health, Uppsala University, Uppsala, - - 2014
To study folic acid intake, folate status and pregnancy outcome after infertility treatment in women with different infertility diagnoses in relation to methylenetetrahydrofolate reductase (MTHFR) 677C>T, 1298A>C and 1793G>A polymorphisms. Also the use of folic acid supplements, folate status and the frequency of different gene variations were studied in women ...
Garcia-Velasco Juan A JA IVI-Madrid, Av Talgo, 68 28035 Madrid, Spain. Electronic address: - - 2014
Worldwide, gonadotrophin-releasing hormone (GnRH) antagonists are gaining ground, and the number of patients being treated for IVF with a GnRH antagonist is increasing. Cycle planning in GnRH antagonist IVF cycles has been a challenge. During the past 2 years, debate has been ongoing about the possible disadvantages of oral contraceptive ...
Nasu Takashi T Department of Pediatrics, Obihiro Kosei General Hospital, Obihiro, - - 2014
Infants often develop hypocarnitinemia and resultant hypoglycemia during long-term treatment with antibiotics that contain pivalic acid, but it is unknown whether maternal treatment with such agents during pregnancy induces hypocarnitinemia in fetuses or neonates. A woman at week 28 of pregnancy was prescribed cefcapene pivoxil for 84 consecutive days for ...
Bodur S S Department of Obstetrics and Gynecology, GATA Medical Faculty , Ankara , - - 2014
To determine the efficacy and safety of primary medical treatment with systemic methotrexate (MTX) in caesarean scar ectopic pregnancy, we conducted a Medline/PubMed search on the relevant English literature from January 1978 to January 2012. The search yielded 27 publications of 40 cases of caesarean scar ectopic pregnancy. The literature ...
Rabiu Kabiru Afolarin KA FWACS FMCOG, Department of Obstetrics and Gynaecology, Lagos State University College of Medicine, Ikeja, Lagos State, Nigeria - - 2014
We studied the practice of malaria prevention and treatment in pregnancy of 394 private medical practitioners in Lagos State, Nigeria using a self-administered pre-tested structured questionnaire. Only 39 (9.9%) respondents had correct knowledge of the World Health Organization (WHO) strategies. Malaria prophylaxis in pregnancy was offered by 336 (85.3%), but ...
Luyckx Mathieu M Gynecology Department, Cliniques Universitaires Saint-Luc, Brussels, Belgium. Electronic address: - - 2014
To study the pregnancy rate after ulipristal acetate (UPA) therapy for fibroids. Retrospective analysis of a series of 52 patients prospectively included in the PGL4001 (ulipristal acetate) Efficacy Assessment in Reduction of Symptoms Due to Uterine Leiomyomata (PEARL) II and III trials. Academic hospital. Among the 52 patients, 21 wished ...
- - 2014
Clinical trials testing infertility treatments often do not report on the major outcomes of interest to patients and clinicians and the public (such as live birth) nor on the harms, including maternal risks during pregnancy and fetal anomalies. This is complicated by the multiple participants in infertility trials which may ...
- - 2014
Clinical trials testing infertility treatments often do not report on the major outcomes of interest to patients and clinicians and the public (such as live birth) nor on the harms, including maternal risks during pregnancy and fetal anomalies. This is complicated by the multiple participants in infertility trials which may ...
Streuli Isabelle I University Hospitals of Geneva and the Faculty of Medicine of the Geneva University, Departement of Gynecology and Obstetrics, Unit for Reproductive Medicine and Gynecological Endocrinology , 30, boulevard de la Cluse, Geneva, 1205 , - - 2014
Introduction: Adenomyosis, characterized by the infiltration of the myometrium by ectopic endometrial islets, is a common condition that causes dysmenorrhea, abnormal uterine bleeding and infertility. Different treatment options exist, including medical and surgical treatments. The most commonly used medications are NSAIDs, progestogens and GnRH agonists (GnRHas). Areas covered: We conducted ...
Arcaniolo Davide D Department of Urology, University of Federico II, Naples. - - 2014
Infertility affects 15% of couples in fertile age. Male factor is a cause of infertility in almost half of cases, mainly due to oligoasthenoteratozoospermia (OAT). The purpose of this study is to review the effects of nutritional supplements as medical treatment for idiopathic male infertility. A Pub Med and Medline ...
Petersen Irene I Department of Primary Care and Population Health, UCL, Rowland Hill St., London NW3 2PF, United Kingdom. Electronic address: - - 2014
Women prescribed antipsychotics face the dilemma on whether to continue medication in pregnancy in terms of balancing risks and benefits. Previous research on other psychotropic medications suggests that many women discontinue treatment in early pregnancy. However, very limited evidence exists on discontinuation of antipsychotic medication. We identified 495,953 pregnant women ...
Kalliala Ilkka I Department of Obstetrics and Gynaecology, Kätilöopisto Hospital, Helsinki University Central Hospital, Sofianlehdonkatu 5 A, 00029 HUS, Helsinki, - - 2014
We performed a retrospective cohort study of 3530 women treated for cervical intraepithelial neoplasia (CIN) in Helsinki University Central Hospital, Finland, to investigate whether CIN treatment itself affects pregnancy incidence and outcome. We estimated the incidence of live births, miscarriages, extrauterine pregnancies, molar pregnancies, and termination of pregnancies (TOPs) before ...
Martin Caitlin E CE Department of obstetrics and gynecology, University of North Carolina hospitals. Electronic address: - - 2014
Prescription opioid abuse is a significant and costly public health problem among pregnant women in the United States. We investigated recent trends in substance abuse treatment admissions for prescription opioids during pregnancy using the Treatment Episodes Data Set. From 1992 to 2012 the overall proportion of pregnant admissions remained stable ...
Moutou C C Université de Strasbourg, Hôpitaux Universitaires de Strasbourg, Service de la Biologie de la Reproduction, CMCO, 19, Rue Louis Pasteur, BP120, 67303 Schiltigheim, - - 2014
How do data in the 12th annual data collection (Data XII) of the European Society of Human Reproduction and Embryology Preimplantation Genetic Diagnosis (PGD) Consortium compare with the cumulative data for collections I-XI? Since the beginning of the data collections, there has been a steady increase in the number of ...
Andrés G G Laboratory of Animal Biotechnology, Faculty of Agronomy, University of Buenos Aires, Buenos Aires, C1417DSE, - - 2014
The current limitations for obtaining ovaries from slaughterhouses and the low efficiency of in vivo follicular aspiration necessitate a complete understanding of the variables that affect oocyte developmental competence in the equine. For this reason, we assessed the effect on equine oocyte meiotic competence and the subsequent in vitro cloned ...
Nekuei Nafisehsadat N Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Isfahan, - - 2014
Preconception interventions in infertile couples can increase the chance of pregnancy and lower its complications. The success in infertility treatment and achieving a successful pregnancy is of great importance among infertile couples compared to others. This study has tried to investigate necessary preconception interventions before beginning of infertility treatment cycle ...
Nargund G G The Centre for Reproduction and Advanced Technology (CREATE Fertility) St Georges House, 3-5 Pepys Road, West Wimbledon, London SW20 - - 2014
A case is reported of a patient with critically low anti-mullerian hormone (AMH) having successful 'rescue' oocyte retrieval in natural in vitro fertilization (IVF) cycle 24 hours after the initial procedure had resulted in no oocyte being collected. Following administration of 10,000 units human chorionic hormone (hCG) a second retrieval ...
Kyrgiou Maria M Institute of Reproductive and Developmental Biology, Department of Surgery & Cancer, Faculty of Medicine, Imperial College, London W12 0NN, UK - - 2014
To determine the impact of cervical excision for cervical intraepithelial neoplasia on fertility and early pregnancy outcomes. Systematic review and meta-analysis of cohort studies. Medline and Embase. Studies assessing fertility and early pregnancy outcomes in women with a history of treatment for cervical intraepithelial neoplasia versus untreated women. We classified ...
McNeel Anthony K - - 2013
Placental separation is complex physiological event in reproductive physiology and the underlying molecular mechanisms remain unclear. When comparing different experiments the timing of tissue collections is a significant consideration due to the variability in time between fetal expulsion and expulsion of the placenta (30 min->24 h). This makes comparison of ...
Huilaja Laura L Deparment of Dermatology and Oulu Center for Cell-Matrix Research, University of Oulu, Oulu University Hospital, Oulu, - - 2013
Gestational pemphigoid (PG), a very rare pregnancy-associated bullous dermatosis, is associated with adverse pregnancy outcome (miscarriage, preterm delivery, foetal growth restriction). The major antigen in PG is collagen XVII (BP180). PG autoantibodies cross-react with collagen XVII in the skin and have been suggested to cause placental failure. On this basis, ...
Whitehead Nedra S - - 2012
PURPOSE: Pregnancy and childbirth are normal conditions, but complications and adverse outcomes are common. Both genetic and environmental factors influence the course of pregnancy. Genetic epidemiologic research into pregnancy outcomes could be strengthened by the use of common measures, which would allow data from different studies to be combined or ...
Zhou Qiongjie - - 2012
OBJECTIVES: This study's aim was to evaluate the effect of preeclampsia and intrauterine growth restriction (IUGR) on fetal cardiac function, and the relationship of the latter with adverse pregnancy outcomes. MATERIAL AND METHODS: We did a cross-sectional study of 132 women with uncomplicated singleton pregnancies, 34 with preeclampsia without IUGR, ...
Gracia Rebeca - - 2012
Fomepizole has been utilized with remarkable success for ethylene glycol and methanol poisonings in children and adults. However, very little information is available regarding the safe and effective use of fomepizole in pregnancy. The goal of this research was to utilize an animal model to investigate the kinetics of fomepizole ...
Wells Sarah Melissa - - 2012
There is growing evidence that heart valves are not passive structures, but can remodel with left ventricular dysfunction. To determine if these tissues remodel under non-pathological conditions, we examined the mirtal valve anterior leaflet during the volume loading and cardiac expansion of pregnancy using a bovine model. We measured leaflet ...
Salamanca Alberto - - 2012
PURPOSE: To provide additional information about embryo morphology sonographic assessment and its correlation with yolk sac. METHODS: A systematic study in 200 consecutive cases of missed abortion <10 weeks diagnosed by transvaginal ultrasound. RESULTS: In 104 gestations of embryos with morphological abnormalities, 88 (84.6 %) were at least 1 week smaller than expected ...
Weintraub Adi Y - - 2012
Abstract Objective: To investigate whether obstetrical complications are increased in pregnancies with a normal karyotype and an abnormal triple test (TT) (≥1:380 or more) where all anylates were within the normal range. Methods: A retrospective cohort study of women who underwent a TT and delivered in a tertiary medical center, ...
Hata Toshiyuki - - 2012
BACKGROUND: Our objective is to present our experience of normal embryonic development and fetal anatomy and fetal anomalies reconstructed employing the three-dimensional (3D) and four-dimensional (4D) HDlive rendering mode. METHODS: A total of 18 normal embryos and fetuses and 21 abnormal fetuses (one case each of thoracic meningocele, thickened nuchal ...
Stamatopoulos Nicole - - 2012
To study whether Chlamydia trachomatis is absent or persists in a latent state in the fallopian tube at the time of laparoscopic salpingectomy for tubal ectopic pregnancy (EP). We examined tissue of the fallopian tubes for the presence of C. trachomatis from women who underwent laparoscopic salpingectomy for EP. Presence or ...
Sakai Atsuhiko - - 2012
A 29-year-old woman was diagnosed with a cervico-isthmic pregnancy based on ultrasound findings at 8 weeks of gestation. At 30 weeks of gestation, placenta previa was confirmed. During cesarean section at 37 weeks, the placenta did not spontaneously detach from the uterus; therefore, we decided to leave it in the ...
Campbell J P - - 2012
Haemorrhage remains an important cause of maternal mortality worldwide. Cell salvage carries a theoretical risk of amniotic fluid embolus syndrome and is too expensive for use in many parts of the world. To explore cheaper options, we investigated whether a leucocyte depletion filter alone removes components of pure amniotic fluid. ...
Pooh Ritsuko K - - 2012
Fetal brain is rapidly developing and changing its appearance week by week during pregnancy. It is quite difficult to observe detailed structure of the brain by conventional transabdominal sonography. Transvaginal high-resolution ultrasound and three-dimensional (3D) ultrasound have been establishing sonoembryology in the first trimester as well as neurosonography. It is ...
Resi Veronica - - 2012
Changes in adipose tissue metabolism are central to adaptation of whole body energy homeostasis to pregnancy. To gain insight into the molecular mechanisms supporting tissue remodeling, we have characterized the longitudinal changes of the adipose transcriptome in human pregnancy. Healthy nonobese women recruited pregravid were followed in early (8-12 wk) ...
Tehli Ozkan - - 2012
Background: The structural changes in filum terminale (FT) may be responsible for tethered cord syndrome (TCS) in children. Although the histological changes in FT related to TCS are well-known, there is no comparative study of the changes which occur in TCS and normal fetal FT samples. The aims of this ...
Sugawara Atsushi - - 2012
Preimplantation genetic diagnosis (PGD) is a genetic screening of embryos conceived with assisted reproduction technologies (ART). A single blastomere from an early-stage embryo is removed and molecular analyses follow to identify embryos carrying genetic defects. PGD is considered highly successful for detecting genetic anomalies, but the effects of blastomere biopsy ...
Savelli Luca - - 2012
We herein report the case of two young nulliparous women with no history of amenorrhea who came to our attention due to the finding of a hypervascularized solid adnexal mass. In both cases a malignant tumor of tubal origin was suspected at transvaginal sonography. Eventually the masses turned out to ...
McLean Kelley C - - 2012
Normal pregnancy results in a prothrombotic state. Studies that have investigated the capacity of pregnant women to generate thrombin are limited. Our aim was to evaluate thrombin generation longitudinally from the preconception period, through pregnancy, and after pregnancy. We evaluated young, healthy nulligravid women (n = 20) at 4 time ...
Nanovskaya Tatiana N TN Department of Obstetrics & Gynecology, University of Texas Medical Branch, Galveston, TX 77555-0587, - - 2012
Determine the bidirectional transfer of oseltamivir carboxylate (OC) across term human placenta and its distribution between the tissue, maternal and fetal circuits. The technique of dual perfusion of placental lobule (DPPL) in its recirculating mode was utilized to determine the transfer of the drug. OC (350 ng/mL) was co-perfused with ...
Rădulescu Micaela - - 2012
Neural tube defects (NTD) are a heterogeneous group of malformations resulting from failure of normal neural tube closure before the fourth and fifth week of embryologic development. The three most common forms of NTD are: anencephaly, encephalocele and spinal dysraphism. Less common forms of neural tube defects include iniencephaly, amniotic ...
Santos T C - - 2012
The histomorphometric and proliferative characteristics of the collared peccary (Tayassu tajacu) placenta and uterus were analyzed. The material was examined by standard histological techniques and histochemistry (PAS, Perls and Alcian Blue pH 0.5 and 2.5%) and the cellular proliferation by AgNORs and flow cytometry. All the analyzed morphometric variables differed ...
Alwasel S H SH Zoology Department, College of Science and Centre of Excellence in Biotechnology Research, King Saud University, Saudi - - 2012
Studies of pregnancies complicated by preeclampsia led to the suggestion that the surface of the placenta is aligned along two axes, measured by its breadth and length. It was hypothesised that tissue along the breadth serves as a nutrient sensor, responding to the mother's nutritional state and fetal nutritional demands, ...
Comas Montse - - 2012
Objective: Tissue Doppler echocardiography is being increasingly used in fetal medicine as a clinical and research tool. The objective of this study was to review the current status of tissue Doppler imaging (TDI) techniques applied to the fetus. Methods: Fetal cardiac function was evaluated using spectral and color TDI modes ...
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