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Results 201 - 248 of 248
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Lazarchick J - - 1986
It has been suggested that the basis for the marked discordance in factor VIII parameters in preeclampsia is the result of proteolysis of the factor VIII procoagulant component (VIII:C) owing to activation of the coagulation system. To investigate this further, levels were compared of factor VIII:C and VIII:C (Ag), the ...
Wong T - - 1986
Active and inactive renin were measured in individual juxtaglomerular apparatus (JGA) and in whole kidney homogenates. The morphology of the JGA was examined in microbiopsy glomerular specimens and in kidneys fixed by arterial perfusion. In rats on high and normal salt intake the total renin content of a single JGA ...
Daniels C R - - 1986
In healthy normotensive pregnancy, a complex functional network develops between the cardiovascular system, the volume and composition of the extracellular fluid and the renin-angiotensin system (RAS). Cardiac output and heart rate increase, but blood pressure is reduced. The kidneys increase in size and both the glomerular filtration rate and renal ...
Joels N - - 1985
The pressor responses to angiotensin II injections of 29, 117 and 468 pmol/kg and infusion at 54 pmol/kg per min were compared in near-term pregnant and matched non-pregnant rabbits. The responses to noradrenaline injections of 652, 2608 and 10 432 pmol/kg and infusion at 1185 pmol/kg per min were similarly ...
Holmes K K - - 1985
To explore of the association of bacterial vaginosis with anaerobic bacterial growth in the vagina, we measured the redox potential (Eh) at the vaginal epithelial surface of women with this syndrome. Among normal women, the value for Eh in the vagina ranged from +322 mV to +137 mV (mean, +170 ...
Apple J S - - 1985
Forty patients were randomized in a double-blind study to compare the safety and diagnostic quality of Hexabrix vs. Renografin-60 without epinephrine in knee arthrography. Hexabrix is a monoacidic dimer of meglumine and sodium salts of ioxaglic acid with a lower osmolality than conventional contrast agents of similar concentration (32% iodine). ...
Willoughby J S - - 1984
Pregnancy should not greatly alter the anaesthetic management of a patient with intracranial aneurysms. Controlled hypotension is the method of choice for meeting surgical requirements. Primary attention to the mother with judicious use of sodium nitroprusside is unlikely to compromise the foetus. Sodium nitroprusside is not teratogenic in animal experiments. ...
Lee J R - - 1984
To determine whether combinations of saline and surface-acting laxatives have any superior action over saline laxatives alone in cleansing the colon, patients having double-contrast barium enema examinations were randomly allocated to magnesium citrate alone and magnesium citrate with either oral or rectal bisacodyl. The addition of bisacodyl conferred no benefit ...
Paller M S - - 1984
The mechanism of decreased pressor responsiveness to pressor agents was examined serially throughout pregnancy in conscious rats. Rats, 15 and 20 days pregnant, showed marked blunting of the pressor response to graded doses of angiotensin, whereas after only 5 days of pregnancy there was a normal response and at 10 ...
Marklund S L - - 1984
A further characterization of human extracellular superoxide dismutase is reported. The study was especially aimed at the interaction with substances known to interfere with CuZn superoxide dismutase and other superoxide dismutases. Extracellular superoxide dismutase is efficiently inhibited by cyanide and is about 3 times more sensitive than is human CuZn ...
Mandelbaum F R - - 1984
Two hemorrhagic factors were isolated from the venom of Bothrops neuwiedi (jararaca pintada) by ammonium sulfate precipitation followed by chromatography on DEAE-Sephadex A-50 and DEAE-cellulose DE-32, gel filtration on Sephadex G-100 and polyacrylamide-gel electrophoresis. These factors were named neuwiedi hemorrhagic factors NHFa and NHFb. They are acidic proteins of pI ...
Linden S - - 1983
Because of possible teratogenicity, lithium should be used during the first trimester only if clinically essential. Lithium levels should be monitored throughout pregnancy and dosage adjusted as necessary. Sodium-restricted diets and diuretics should be used with caution. Lithium dose should be reduced with the onset of labor. Mothers who choose ...
Weissberg P L - - 1983
In a cross sectional study of 137 women of childbearing age (16-40) the effects of normal pregnancy, hypertensive pregnancy, and oral contraceptives on red cell electrolyte content and sodium efflux rates were examined and the results compared with values in a control group of normotensive, non-pregnant women. Efflux rate constants ...
Caldwell J R - - 1983
One hundred forty-one subjects with osteoarthritis completed this double-blind, multicenter, crossover trial comparing four nonsteroidal anti-inflammatory (NSAI) agents after single-blind aspirin stabilization. Preferences of both patients and physicians showed the following rank order from most to least preferable: tolmetin sodium, naproxen, ibuprofen, fenoprofen calcium. By all but three of more ...
Perentesis G P - - 1983
The stability of bretylium tosylate when mixed with large-volume parenteral (LVP) solutions was assessed over a four-week period, and the compatibility of bretylium tosylate when mixed with eight frequently used drugs was evaluated. Bretylium tosylate admixtures of approximately 1 mg/ml were prepared in both polyvinyl chloride (PVC) bags and glass ...
Jaspers W J - - 1983
Angiotensin II (A-II) sensitivity was determined in 23 nonmedicated nulliparas in the third trimester of pregnancy, before and after a 7- to 10-day period of bed rest and a strongly sodium-restricted diet (maximal 20 mmol Na+/24 hr). Seventeen nulliparous women had pregnancy-induced hypertension (PIH). The effective pressor dose (EPD), that ...
Boyd R D - - 1983
The volumes of distribution of 22Na and 24Na, 51Cr-EDTA and albumin labelled with 131I and 125I were measured in cotyledons and skeletal muscle taken from pregnant sheep and the fetuses near term. Radiolabelled substances were injected through chronically implanted catheters 0.5-3.2 hr before removal of tissues in 'short-term' experiments and ...
Jakinovich W W - - 1983
The sugar methyl 4,6-dichloro-4,6-dideoxy-alpha-D-galactopyranoside (DiCl-gal) is a new type of inhibitor of the gerbil's electrophysiological taste response to sucrose or saccharin. Saturated solutions of this compound alone barely stimulate the gerbil's taste nerve. But, when mixed with sucrose or saccharin, DiCl-gal suppresses the gerbil's taste response to these two sweeteners. ...
Horton R J - - 1983
The comparative safety and efficacy of the orally active gold compound, auranofin, and parenteral gold compounds, principally gold sodium thiomalate, are reviewed. No difference in efficacy was detected in eight of the 12 published studies which compared auranofin and gold sodium thiomalate. Two studies favoured auranofin and two gold sodium ...
Hinton D E - - 1982
Studies on isolated perfused tubules of the tiger salamander (Ambystoma tigrinum) have shown that the distal nephron is heterogeneous with respect to function (Stoner, 1977). In this study, the initial portion of the distal tubule (diluting segment) exhibited a voltage, positive in the lumen, and a net absorption of chloride. ...
Normann S J - - 1982
Pregnancy inhibits macrophage accumulation within the peritoneal cavity of Wistar rats when inflammation is induced by phytohaemagglutinin (PHA). The inhibition of macrophages was considerably greater than that of polymorphonuclear leucocytes (PMNs) induced by sodium caseinate. Pregnancy did not significantly alter macrophage accumulation to PHA injected into the pleural space or ...
Rapoport J - - 1982
We wished to compare the natriuretic and diuretic effect of extracellular volume expansion (ECVE) with 0.9% NaCl to that obtained with up-to-the-neck immersion (NI) in healthy volunteers. Clearance techniques during maximal antidiuretic hormone suppression were utilized to pinpoint the sites of tubular NaCl reabsorption. Mean glomerular filtration rate (GFR) did ...
Lindbloom G - - 1982
The Rotter, Adult Nowicki-Strickland, and Levenson IE scales were completed by 175 undergraduate students. Factor analyses reconfirmed the factor structure of the Levenson IE scale. Partial correlation analyses showed that the portion of common variance shared by the Rotter IE and the Adult Nowicki-Strickland IE scales associated closely with Levenson's ...
Oats J N - - 1982
In a prospective study the interactions between ACE and the renin-angiotensin system in 18 primigravid normotensive women were investigated throughout pregnancy. ACE activity was found to be depressed throughout pregnancy, rising in the last trimester and returning to non-pregnant values by 6 weeks post partum. No significant differences were found ...
Oney T - - 1982
Normal pregnancy is associated with refractoriness to the pressor effects of i.v. administered angiotensin II (A II). In pre-eclampsia, this refractoriness to A II is lost several weeks prior to the increase of blood pressure. Infusions of 200 ml of 3% saline or of 40% sorbitol over 30 min, or ...
Atherton J C - - 1981
1. Glomerular filtration rate (G.F.R.) and salt and water reabsorption were measured in age-matched (12- to 13-week-old) virgin rats and rats at different stages of pregnancy and infused with saline at 37.5 and 200 microliters/min. 2. G.F.R. and salt and water reabsorption were significantly higher in early pregnancy and remained ...
Rickwood A M - - 1980
Phimosis, defined as scarring of the tip of the prepuce, was studied prospectively in a series of 23 boys aged 4 to 11 years. There was little to support the contention that the condition is caused by trauma, or by ammoniacal or bacterial inflammation of the prepuce, nor could any ...
Machin S J - - 1980
This paper describes two family members who have a combined hereditary deficiency of factors VII and VIII. The propositus, a 16-year-old male, presented with recurrent gastrointestinal bleeding. He and his mother had moderate defects of factors VII and VIII. The propositus received factor VIII cover, during and after a laparatomy. ...
Koller L D - - 1979
Polycythemia developed in progeny from mothers who were exposed during pregnancy to a combination of methylmercury chloride plus ethylurea and sodium nitrite. The polycythemia occurred as early as one month of age and as many as 24% of the offspring developed the polycythemic condition. Many features of this condition are ...
Matsusaki K - - 1979
Methods for removal of the chloride interferences in determination of aluminium by atomic-absorption spectrometry with a graphite furnace have been investigated. Two mechanisms of chloride interference have been established. The first arises from co-ordination of the chloride to aluminium. This interference can be removed by preventing the co-ordination. The other ...
Dyer R S - - 1979
Two types of AD and post-AD sequences are described. Type 1, which were most common (83%), are followed by a profound post-ictal depression (PID). PIDs can be quantitatively measured by integrating the EEG. The post-ictal EEG power normally returned to 75% of its prestimulation power within 4-5 min. PIDs are ...
Isichei U P - - 1978
Serum and urine electrolyte changes were studied in 55 primigravid African women during pregnancy and the postnatal period. The findings suggest that there is a fall in the serum sodium in the first trimester, which is followed by a gradual and steady rise throughout pregnancy. The serum potassium did not ...
Donchin Y - - 1978
A 25-year-old woman in the 7th month of pregnancy was operated upon for a ruptured cerebral aneurysm. Sodium nitroprusside was used to achieve effective controlled hypotension. Signs of foetal distress were transient. Subsequent delivery was spontaneous and uneventful. Development of the child at 2 yr was satisfactory. The various physiological ...
Barry R E - - 1978
The author points out that because a high intake of Vitamin D and calcium is normally encouraged in pregnancy, care should be taken in the prescription of certain antacids likely to cause alkalosis. Calcium-containing antacids are probably best avoided because of nocturnal acid rebound. Because of undesirable fluid retention in ...
Ala-Huikku K - - 1977
The occurrence of C. botulinum on two Finnish rainbow trout farms were studied. C. botulinum type E toxin was detected from samples of fish intestines in 10% and 4% of the samples and in 0% and 100% of dam bottom sediments, respectively. The toxin formation of inoculated C. botulinum type ...
Robillard J E - - 1977
The maturation of the glomerular filtration rate (GFR) and the interrelationship between the GFR and the renal transport of sodium and chloride have been evaluated during the last trimester of gestation with the use of long-term experiments in fetal lambs. An increase in GFR (milliliters per minute) parallel to the ...
Halla J T - - 1977
During gold sodium thiomalate (GST) therapy, 15% of 100 unselected patients described recurring postinjection reactions (PIRs), consisting of transient stiffness, arthralgias, myalgias, and constitutional symptoms. Six patients with more severe reactions requested discontinuation of chrysotherapy and for these, gold thioglucose (GTG) substitution abolished or amelioriated the reactions. The major significance ...
Marsico A R - - 1976
In an attempt to evaluate and improve the Goeckerman treatment of psoriasis, combinations of tar and ultraviolet (UV) light were studied. The effects of UV irradiation alone, of curde coal tar (CCT) ointment alone, and of UV irradiation with 1% CCT ointment and with 6% CCT ointment on psoriatic lesions ...
Börzsönyi M - - 1976
Swiss mice at different stages of pregnancy were treated intragastrically with the pesticide Carbendazim (MBC, BCM, methyl-2-benzimidazole carbamate) together with sodium nitrite. Lymphomas developed in 33.3% of young mice whose mothers were treated in the first week of pregnancy, in 53.3% of whose mothers were treated during the second week, ...
Sechser T - - 1976
Embryotoxic properties of Shigella dysenteriae and Clostridium perfringens toxins, of E. coli endotoxin, V. cholerase and E. coli enterotoxins were compared in mice. E. coli endotoxin has embryotoxic effects at all stages of pregnancy. E. coli enterotoxin V. cholerae enterotoxin and Shigella dysenteriae toxin are most effective mainly at earlier ...
Fedrick J - - 1973
To assess the significance of the length of time between two pregnancies on the outcome of the second we used information collected by the British Perinatal Mortality Survey of 1958. From questionnaires on the 16,994 singleton births in the first week of March 1958 and the 7,117 singleton stillbirths and ...
Ehrlich E N - - 1972
The role of augmented aldosterone production in pregnancy is poorly understood. Whereas some consider aldosterone secretion in pregnancy excessive, others suggest that this is a compensatory phenomenon. According to yet another view, mechanisms other than the renin-angiotensin-aldosterone system control sodium homeostasis in pregnancy. Metabolic balance studies were performed on 14 ...
Wormald P J - - 1970
In an established burns centre which moved from an old building to new purpose-designed premises, colonization rates of patients' burns with Staphylococcus aureus, Pseudomonas aeruginosa and other Gram-negative bacilli were not reduced. Colonization rates with Streptococcus pyogenes increased but the increase was mainly due to multiple importations in the new ...
Schiller K F - - 1970
In a study of 2,149 emergency admissions because of haematemesis or melaena during a 15-year period, the sex ratio, age distribution, and main diagnostic groups showed no major change. Various factors affected the prognosis, such as the age of the patient, the underlying diagnosis, a low blood pressure on arrival ...
Masson G M - - 1966
After a short period of tachyphylaxis, there is a marked and sustained enhancement of pressor re sponses to renin and angiotensin during chronic administration of renin.
Dainty J - - 1966
1. Estimates of the magnitudes of the unstirred regions associated with isolated frog skin in sulphate Ringer's solution have been made under different stirring conditions.2. The method of investigation was an analysis of the time course of the p.d. transients which occurred when external sodium concentration and internal potassium concentration ...
GIESE A C - - 1960
X-rays and ultraviolet radiations delay regeneration and division of Blepharisma undulans. Irradiated blepharisma which have not been cut divide once or twice fairly soon after the controls then they cease dividing for a period of time (stasis) which may last for many hours or even days. Once they recover from ...
MOE A E - - 1955
Even small losses of gastrointestinal secretions when combined with reduced intake of electrolytes may seriously disturb electrolyte balance. Knowledge of the ionic composition of secretions lost is essential in planning therapy. Loss of gastric contents usually results in excessive loss of chloride; in achlorhydria this is not the case. Loss ...
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