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Erdo─čan D - - 1996
In this study, fetal joint abnormalities caused by cytosine arabinoside, caffeine, sodium salicylate, and retinyl acetate administration during pregnancy, were investigated. In the cytosine-arabinoside-administered group, complete disappearance of joint spaces in the forelimbs, and narrowing or complete disappearance of joint spaces in the hindlimbs was highly noticeable. In the caffeine ...
Tresham J J - - 1996
Reduced pressor responsiveness to angiotensin II (Ang II) during pregnancy and sodium depletion is a well-known but little understood phenomenon; whether the same mechanisms are involved in both situations is unclear. In pregnant humans, altered vascular reactivity to norepinephrine (NE) has also been demonstrated. Nitric oxide (NO) has been implicated ...
Lumbers E R - - 1995
1. From studies in chronically catheterized fetal sheep and other species, it can be shown that the renin-angiotensin system (RAS) is active during intra-uterine life. Levels of angiotensin II (AII) in fetal sheep are similar to maternal. 2. The fetal RAS plays a role in maintenance of arterial pressure. The ...
Ikewaki K - - 1995
HDLs are heterogeneous in their apolipoprotein composition. Apolipoprotein (apo) A-I and apoA-II are the major proteins found in HDL and form the two major HDL subclasses: those that contain only apoA-I (LpA-I) and those that contain both apoA-I and apoA-II (LpA-I:A-II). Substantial evidence indicates that these two subclasses differ in ...
Okamoto T - - 1995
The water and electrolyte balance was studied in 31 patients with ulcerative colitis (UC) and 22 with familial adenomatous polyposis (FAP) who underwent staged surgery involving colectomy and ileal J pouch-anal anastomosis (IAA), preoperatively, after terminal ileostomy, after high ileostomy, and after ileostomy closure. Serum electrolytes did not differ between ...
Janicka L - - 1995
We have investigated the effect of intraperitoneal gentamicin on dialysis efficiency in 10 intermittent peritoneal dialysis (IPD) patients. The following parameters were measured: net ultrafiltration (UF); concentration ratios (D/P) of urea, creatinine, potassium; peritoneal clearances (ml/min) of urea, creatinine, potassium; mass transfer of sodium (MTNa); sodium sieving index (SCNa). It ...
Atherton J C - - 1994
Pregnancy in the rat is accompanied by enhanced reabsorption of salt and water throughout most, if not all, of the gestational period. Many mechanisms have been suggested but definitive answers are still awaited. The major area of controversy centres around the detection of changes at term. There is general agreement ...
Li L - - 1994
Recent micropuncture studies showed the existence of high concentrations of angiotensin II (ANG II) in proximal tubular fluid. In the present study, we have examined the effect of luminal ANG II, alone and in combination with peritubular ANG II, on fluid transport (JV) in the isolated perfused rabbit proximal convoluted ...
Bolton L M - - 1994
OBJECTIVE: Our purpose was to describe the alterations in erythrocyte sodium pump kinetics and sodium content occurring during the puerperium. STUDY DESIGN: Twelve healthy primigravid women were studied serially from late pregnancy until 20 weeks after delivery. Erythrocyte sodium pump rate constant, maximum velocity, and sodium affinity were calculated from ...
Boyle M B - - 1994
The mechanisms responsible for the onset of vigorous contractile activity in uterine muscle at the time of parturition, reversing the obligatory quiescence of pregnancy, remain poorly understood. We here describe the expression in myometrium from human and from timed-pregnant rats of an mRNA species encoding a voltage-sensitive sodium channel. The ...
Marmor A - - 1993
RATIONALE AND OBJECTIVES: In a previous study, intrauterine injection of meglumine-sodium diatrizoate (high osmolar contrast media) during hysterosalpingography was found to induce lengthening of the QTc interval on electrocardiography. To evaluate the relationship between high osmolality and electrocardiographic changes during intrauterine injection, the authors evaluated the effect on QTc of ...
Didden M A - - 1993
To elucidate the physiology of active sodium transport (expressed as erythrocytic ouabian-sensitive sodium efflux rate constant = ERCos) in pregnancy and the influence of dietary sodium intake on that transport, active sodium transport was measured in 52 healthy pregnant women in week 16, 20, 24, 28, 32, 36 or week ...
Quillen E W EW - - 1992
To determine the effects of long-term changes in sodium intake on mean arterial pressure (MAP) regulation during pregnancy, nonpregnant (n = 16) and 110- to 140-day pregnant (n = 13) ewes received total daily sodium intakes of 10, 30, 100, 400, and 1,200 mmol for 7 days. The sheep were ...
MacPhail S - - 1992
OBJECTIVE: To determine if erythrocyte sodium pump function is altered with the onset of pregnancy induced hypertension. DESIGN: A prospective descriptive study. SUBJECTS: Thirty-two primigravid women with pregnancy-induced hypertension (17 had proteinuria) and 32 gestation-matched normotensive primigravid pregnant women were studied and measurements repeated 20 weeks after delivery. INTERVENTION: Erythrocyte ...
McInnes C - - 1992
The ability of low-frequency (200 Hz) acoustic energy to reduce the adherence of Actinomyces viscosus T14V to saliva-treated hydroxyapatite (SHA) disks was studied. An acoustic pressure range between 0 and 65 kPa and exposure durations between 0 and 8 min were used to study the levels necessary to significantly alter ...
Duckworth R M - - 1992
The aims of this work were (a) to assess the oral bioavailability of fluoride delivered from dentifrices and (b) to test for a possible link between the results and clinical data obtained with the same dentifrices. Oral fluoride concentrations were measured in samples of saliva and plaque taken from seven ...
Bloomfield S F - - 1992
Solutions of chlorine-releasing agents (CRAs) show varying activity against Bacillus subtilis spores; sodium hypochlorite (NaOCl) shows higher activity than sodium dichloroisocyanurate (NaDCC) which is more active than chloramine-T. Investigations with coat- and cortex-extracted spores indicate that resistance to CRAs depends not only on the spore coat but also the cortex. ...
Rutherford P A - - 1992
Erythrocyte sodium-lithium countertransport activity is increased in a subgroup of patients with essential hypertension but activity also rises temporarily during normal pregnancy. It is not known if the mechanism of raised activity is the same in both of these situations. Standard sodium-lithium countertransport activity and its kinetic characteristics (sodium affinity ...
Steegers E A - - 1991
OBJECTIVE: To study the possible pathophysiological implications of long continued dietary sodium restriction in pregnancy. DESIGN: Longitudinal prospective randomized study of the effects of a low sodium diet compared with unrestricted sodium intake in pregnancy. SETTING: Academic Department of Obstetrics and Gynaecology at Sint Radboud Hospital, Nijmegen, The Netherlands. SUBJECTS: ...
Caplain H - - 1991
A single blind placebo controlled, cross-over study comparing a new microencapsulated potassium chloride tablet (MET) with two reference formulations of oral potassium, potassium chloride solution (PS) and potassium chloride wax-matrix tablets (WMT), was performed in 12 normal healthy volunteers. Urinary potassium excretion was the main criterion of comparison. Results showed ...
Frankmann S P - - 1991
Following recovery from experimental sodium depletion, both the need-free and the future need-induced NaCl intakes of the rat are increased. The present experiments asked whether a naturally occurring episode of sodium need, pregnancy and lactation, would also enhance NaCl intake. The daily 0.3 M NaCl intake of Long-Evans rats increased ...
Schrier R W - - 1991
Primary peripheral arterial vasodilation with relative underfilling of the arterial circulation occurs in early pregnancy and leads to several consequences, including decreased systolic and diastolic blood pressures, enhanced cardiac output secondary to afterload reduction, stimulation of the renin-angiotensin-aldosterone axis, nonosmotic stimulation of thirst and vasopressin release, and renal sodium and ...
Eschenbacher W L - - 1991
Although it is recognized that inhalation of acid aerosols by subjects with asthma can cause bronchoconstriction, the effects of the inhalation of an alkaline aerosol are unknown. When supplemental inflatable restraints (automobile air bags) are deployed an alkaline aerosol is released. This aerosol is composed of particles of sodium carbonate ...
Kram H B - - 1991
In the present in vitro study, we investigated the duration of action and antibacterial effects of nonautologous fibrin glue (FG) combined with antibiotics (Abs) including Ciprofloxacin, Teicoplanin, Cefoxitin, and Gentamicin; the effect of FG alone on bacterial growth was also evaluated. The rate of Ab diffusion from combined FG-Ab clots ...
Miyasaki K T - - 1990
Neutrophil myeloperoxidase (MPO) adsorbs to bacteria as a pre-requisite for killing by the MPO/hydrogen-peroxide/chloride system. Three chromatographically distinct isoforms of MPO (MPO I, MPO II, and MPO III) have been isolated from human neutrophils. The purpose of this study was to determine whether oral bacteria--including Actinobacillus actinomycetemcomitans, Capnocytophaga sputigena, Haemophilus ...
Braga P C - - 1990
The topical tolerability of an intranasal salmon calcitonin spray preparation, of the excipients alone and of sodium taurocholate has been studied by assessment of the mucociliary transport velocity (MTV) on the frog's palate. The rate of mucus transport was investigated in 3 groups of animals (Rana esculenta; 6 frogs per ...
Poston L - - 1990
In blacks and whites of similar socioeconomic background, the incidence of pregnancy-induced hypertension (PIH) is probably the same. In underdeveloped countries, however. PIH is often a life-threatening complication of pregnancy. Recent theories as to the etiology of PIH include the suggestion that vascular tone may be increased as a result ...
Nicolaidis S - - 1990
The propensity to prefer and to consume salty foods varies considerably from person to person, and excessive salt intake has been linked to a number of pathological conditions. Extracellular dehydration occurs in humans after vomiting or diarrhea and is commonly observed during pregnancy. Because the hormonal responses to extracellular dehydration ...
Hines T - - 1989
It is known that the pressor response to intravenous angiotensin II (ANG II) is blunted in pregnancy. In the present study we examined the pressor response to intracerebroventricular ANG II to determine whether central ANG II effects are also attenuated in conscious pregnant rats. Two to three days before experimentation, ...
Stratta P - - 1989
The possibility of evaluating the ratio between aldosterone and atrial natriuretic peptide (ANP) instead of the two hormones by themselves in studying sodium handling in normal pregnancy and in preeclampsia in the steady state and following albumin infusion was examined in this study. In 32 normal pregnancies monitored monthly, the ...
Addy M - - 1989
For antimicrobials such as chlorhexidine antiplaque activity appears due to persistence of considerable antimicrobial action in the mouth. The substantivity of antimicrobial compounds can be evaluated by measuring the magnitude and duration of salivary bacterial counts following a single exposure. Such data has been shown to correlate with plaque inhibitory ...
Durbin P W - - 1989
The linear tetracarboxycatecholate ligand, 3,4,3-LICAM(C) (N1,N5,N10,N14-tetrakis(2,3-dihydroxy-4-carboxybenzoyl-tetraaza tet radecane, tetra sodium salt) injected within 1 h after injection of Pu(IV) citrate, removes about the same fraction of Pu from animals as CaNa3-DTPA (diethylenetriaminepentaacetate, calcium, sodium salt) but removes less inhaled Pu than CaNa3-DTPA and leaves a Pu residue in the renal ...
Tupker R A - - 1989
The rôle of different factors in the susceptibility of the skin to weak irritants was studied by means of multiple linear regression models. The skin of 37 healthy subjects was exposed to a solution of sodium lauryl sulphate of low molarity 2 x daily for 4 days. The condition of ...
Mehta A R - - 1989
Early pregnancy factor (EPF) is a pregnancy-associated protein detected in the maternal serum by using the rosette inhibition assay and by evaluating the suppression of adoptive transfer of contact sensitivity. Because of its inhibitory effect on the functional reactivity of immunocompetent cells, EPF is thought to be involved in immunoregulation ...
Valdés E - - 1989
Fillets of a hake, Merluccius merluccius hubbsi, were exposed to 2 kGy, 6 kGy, and 10 kGy of ionizing radIation from a Cobalt 60 source and were subsequently stored frozen at 0 degree C. Both these irradiated samples and control samples were examined to determine their bacterial counts and organoleptic ...
Brown M A - - 1988
To examine the short-term regulation of sodium excretion, plasma volume, and the renin-aldosterone system in pregnancy, women in their first pregnancy received either a high-salt (HS) (250 mmol/day) or a low-salt (LS) (20 mmol/day) diet for 7 days during the second and third trimester and after delivery (total 213 studies). ...
Shopova M - - 1988
The influence of the polarity of the medium on the efficiency of Type I and Type II photosensitization as carried out by hematoporphyrin and its derivative Photofrin II was studied by EPR techniques. Our results suggest that porphyrin aggregates do not participate as such in the photosensitized processes. Thus, the ...
Milligan S R - - 1988
Vascular permeability in the uterus and other tissues of mice was assessed using the accumulation of 125I-human serum albumin 30 min after its intravenous injection. The anaesthetic agent employed for the 125I-albumin injection differentially affected the estimates of vascular permeability: intraperitoneal (i.p.) tribromoethanol of pentobarbitone sodium produced significantly higher values ...
Brown M A - - 1988
One hundred fifty-eight intravenous saline solution infusions (3 mmol Na per kilogram body weight) were performed in (1) normal primigravid women during the second and third trimesters and post partum, after 1 week of either a high, low, or ad libitum salt intake; (2) normotensive primigravid women during midpregnancy who ...
Brown M A - - 1988
Twelve women in their first 3 months of pregnancy received an i.v. saline load (3 mmol sodium/kg) and a graded infusion of angiotensin II (Ang II; i.e. 4, 8 and 16 ng/kg per min). As controls, twelve comparable pregnant subjects received the saline infusion alone. Eight non-pregnant women underwent both ...
Gallery E D - - 1988
1. Active electrolyte transport was examined in erythrocytes from women in the second and third trimesters of pregnancy and post partum, and compared with that in ovulating women. 2. There was a significant reduction in intracellular sodium ([Na]i) and increase in intracellular potassium ([K]i) in pregnancy with a return towards ...
Atherton J C - - 1988
1. Sodium and water reabsorption were determined in virgin controls and rats at 9 and 20 days of pregnancy during a water diuresis induced and maintained by infusion of 2.5% dextrose and in normally hydrated women during the third trimester and again 2-3 months after delivery. 2. Reabsorption from the ...
Borg K - - 1988
Brown trout, Salmo trutta, were exposed to water containing 0.1 microgram/l 203Hg2+, alone or with potassium ethylxanthate (PEX), sodium isopropylxanthate (SIX), sodium diethyldithiophosphate (SEP), sodium diisopropyldithiophosphate (SIP), sodium dimethyldithiocarbamate (SMC), sodium diethyldithiocarbamate (SEC) or sodium pyridinethione (SPyr), respectively. After 1 week the uptake and distribution of the 203Hg2+ in the ...
Michell A R - - 1988
Sodium preference was examined in three groups of sheep which had all sustained two consecutive pregnancies and lactations on either adequate sodium intakes (group C) or low sodium diets (B and C). Group B received a potassium supplement as well as a low sodium diet during the present experiment. No ...
Gallery E D - - 1987
In this chapter are outlined the many factors involved in the regulation of sodium and volume homeostasis in normal human pregnancy and their interrelationships. New developments concerning the role of sodium/potassium ATPase, atrial natriuretic peptide, arginine vasopressin and angiotensin II as regulatory forces are outlined, together with a review of ...
Illowsky B P - - 1987
Considerable controversy has followed the recent publication of studies indicating that central pontine myelinolysis is caused by rapid correction of hyponatraemia. Alternative suggestions have been that myelinolysis is due to uncorrected hyponatraemia, that it occurs only with over-correction of hyponatraemia or that it is due to coincidental hypoxia. The following ...
Schrier R W - - 1987
With pregnancy, the expansion of plasma and extracellular fluid volume, increased cardiac output, and increased glomerular filtration rate (GFR) and renal blood flow (RBF) are compatible with primary renal sodium and water retention with secondary enlargement of the vascular compartment (overfill hypothesis). Alternatively, a primary enlargement of the vascular compartment ...
Gallery E D - - 1987
Sodium and water retention are normal accompaniments of pregnancy achieved by many significant and complex interrelated alterations in homeostatic forces. Furthermore, potentially harmful derangements in sodium and volume control are found in women with pregnancy-associated hypertension (P-AH, preeclampsia). None of these alterations is completely understood, and many of them appear ...
Barron W M - - 1987
This article reviews alterations in volume and sodium handling during rat pregnancy, noting similarities and contrasts to events in human gestation. Gravid rodents undergo extracellular and plasma volume increases of 50% to 70%, and these changes accompany a marked cumulative sodium retention shared by both dam and fetuses. Pregnancy alters ...
Schindler M - - 1987
Whole rat liver nuclei were reacted with UDP-[14C]galactose in the presence of bovine beta(1----4) galactosyltransferase. The reaction mixture was electrophoresed on a reducing sodium dodecyl sulfate-polyacrylamide gel. Autoradiograms of the gel demonstrated a major labeled broad band migrating with an apparent molecular weight of 65,000-66,000. A number of other less ...
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