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Becker Rolf - - 2012
OBJECTIVE: To assess the prevalence and detection rate of major anomalies (MAs) by applying first trimester anomaly scan (FTAS) including first trimester fetal echocardiography (FTFE) to all fetuses and discuss ethical implications. METHODS: The study group included 6879 consecutive fetuses with known outcome of pregnancy (follow-up: 98%), 6565 with 'normal' ...
Mamo Solomon - - 2012
Successful growth and development of the post-hatching blastocyst and pregnancy establishment are a result of the interaction between a competent embryo and a receptive uterine environment. We examined the global transcriptome profiles of the Day 16 bovine conceptus and pregnant endometrium tissues using RNA-Seq to identify genes that contribute to ...
Luria Oded - - 2012
OBJECTIVE: The authors aimed to study the contractility responses of normal and fetal growth restriction (FGR) placentas to prostaglandin E(2) (PGE(2) ) and to correlate the results to subsequent placental histological analysis. METHOD: A dual-perfused single cotyledon model was used. Placentas from pregnancies complicated by FGR and from normal pregnancies ...
Ghi Tullio - - 2012
OBJECTIVE: To standardize the evaluation of normal tentorium insertion and normal rotation of the cerebellar vermis over the brainstem, using two novel measurements: the brainstem-tentorium angle (BT angle) and the brainstem-vermis angle (BV angle). We also aimed to test the reproducibility of these measurements. METHODS: Prospective observational study including normal ...
Roberts James M - - 2012
The root cause of preeclampsia is the placenta. Preeclampsia begins to abate with the delivery of the placenta and can occur in the absence of a fetus but with the presence of trophoblast tissue with hydatidiform moles. In view of this, study of the placenta should provide insight into the ...
Mahmoudian Alireza - - 2012
The aim of the present study was to determine the effects of valerian (Valeriana officinalis) consumption in pregnancy on cortical volume and the levels of zinc and copper, two essential elements that affect brain development and function, in the brain tissues of mouse fetuses. Pregnant female mice were treated with ...
Liao S B - - 2012
Context:Tubal ectopic pregnancy (tEP) is currently the leading cause of pregnancy-related deaths during the first trimester. Our current knowledge on the molecular pathogenesis is limited.Objective:The objective of the study was to find out the possible role of adrenomedullin (ADM) in the pathogenesis of tEP.Design:This was an experimental in vitro study ...
Cetin I - - 2012
In the last 2 decades, a large proportion of studies have focused on the relationship between maternal periodontal disease and poor obstetric outcomes. The aim of the present review is to summarize the current knowledge about human studies on the pathogenetic mechanisms linking periodontal diseases with adverse pregnancy outcomes. A ...
Vargis Elizabeth E Department of Biomedical Engineering, Vanderbilt University, VU Station B, Box 351631, Nashville, TN 37235, - - 2012
The goal of this research is to determine whether Raman spectroscopy (RS), an optical method that probes the vibrational modes of tissue components, can be used in vivo to study changes in the mouse cervix during pregnancy. If successful, such a tool could be used to detect cervical changes due ...
Green Jacob C - - 2012
The objective was to determine if lactation affects fetal and placental development from day 28 to 42 of gestation. Bos taurus Holstein cows were assigned to one of two treatments immediately after parturition (lactating (n = 23) or nonlactating (dried off immediately after calving; n = 20)). Cows were inseminated ...
Enders A C - - 2012
Endotheliochorial placentas occur in orders from all four major clades of eutherian mammal. Species with this type of placenta include one of the smallest (pygmy shrew) and largest (African elephant) land mammals. The endotheliochorial placenta as a definitive form has an interhemal area consisting of maternal endothelium, interstitial lamina, trophoblast, ...
Luewan Suchaya - - 2012
OBJECTIVE: To establish normal reference ranges of inferior vena cava (IVC) Doppler velocities in normal singleton pregnancies from 14 to 40 weeks. METHODS: A prospective descriptive study was conducted on normal singleton pregnancies with confirmed gestational age. The sonographic measurements of IVC Doppler indices, including preload index, peak velocity index ...
Gourgiotis Demetrios - - 2012
Abstract Objective: To investigate bone and connective tissue collagen turnover in intrauterine-growth-restricted-(IUGR) pregnancies, by determining circulating markers of type I collagen synthesis (carboxy-terminal propeptide of type I procollagen [PICP], representing bone formation) and degradation (cross-linked telopeptide of type I collagen [ICTP], representing bone resorption), as well as type III collagen ...
Carey Satterfield M - - 2012
The global incidence of human obesity has more than doubled over the past three decades. An ovine model of obesity was developed to determine effects of maternal obesity and arginine supplementation on maternal, placental, and fetal parameters of growth, health, and well being. One-hundred-twenty days prior to embryo transfer, ewes ...
Zaher H - - 2012
The combined thickness of the uterus and placenta (CTUP) is one of the characteristics that can be used to assess fetal development and/or placental function in bovine. The current study was designed to establish reference values for the CTUP throughout pregnancy in normal pregnant buffalo-cows. The CTUP at the intracotyledonary ...
D'Ippolito Silvia - - 2012
Latter half of pregnancy is characterized by a "physiological diabetogenic state" since changes in insulin-sensitivity have been well documented. These changes ensure continuous supply of nutrients to the growing fetus. In the last years the role of adipocyte-derived signaling molecules, collectively known as adipokines has been object of different in ...
Onugoren Onur - - 2012
Abstract Objective: Tissue-tracking echocardiography (TTE) is a method for quantitative assessment of myocardial contraction and relaxation. The purpose of this study was to assess the feasibility of TTE in fetuses and investigate fetal myocardial properties in normal pregnancies. Methods: Two hundred thirty pregnant women participated in the study. Fetal four-chamber-view ...
Elmstedt Nina - - 2012
Present data regarding how the fetal heart works and develops throughout gestation is limited. However, the possibility to analyze the myocardial velocity profile provides new possibilities to gain further knowledge in this area. Thus, the objective of this study was to evaluate human fetal myocardial characteristics and deformation properties using ...
Mendez Natalia - - 2012
Surprisingly, in our modern 24/7 society, there is scant information on the impact of developmental chronodisruption like the one experienced by shift worker pregnant women on fetal and postnatal physiology. There are important differences between the maternal and fetal circadian systems; for instance, the suprachiasmatic nucleus is the master clock ...
Kodandapani Sreelakshmi S Department of Obstetrics and Gynecology, Kasturba Medical College, Manipal University, Manipal 576104, - - 2012
Chorioangioma is a benign angioma of placenta arising from chorionic tissue. Large chorioangioma has unfavourable effects on both mother and fetus. We describe a case with large chorioangioma that had a poor outcome on the fetus. We also reviewed the literature on prognostic factors affecting fetal outcome.
Azargoon Azam A Department of Gynecology and Obstetrics, Semnan University of Medical Sciences, Semnan, - - 2012
Clomiphen citrate (CC) is the first line therapy for women with infertility and poly cystic ovary syndrome( PCOS). However, 20-25% of women are resistant to CC and do not ovulate. The objective of this study was to evaluate the efficacy of sequential treatment of metformin and incremental doses of letrozole ...
Sekeroglu Hande Taylan HT From the Department of Ophthalmology, Cukurova University, Adana, - - 2012
To present a case of frosted branch angiitis in a pregnant woman. A 27-week pregnant 18-year-old woman was presented with bilateral decreased visual acuity. Fundoscopy showed typical appearance of frosted branch angiitis. A good spontaneous clinical improvement was observed during systemic evaluation. No treatment was started. Frosted branch angiitis may ...
Shirasawa A - - 2011
Recipient animals for bovine embryo transfer (ET) are routinely selected according to the morphology of the corpus luteum (CL) estimated by rectal palpation. However, rectal palpation is not a precise method of diagnosing the functional status of a CL. Ovarian ultrasonography (US) may be used to improve such diagnoses. The ...
Grattan Dave - - 2011
Prolactin is a pregnancy hormone that is essential for development of the mammary gland for milk production. In addition, prolactin exerts important actions in the maternal brain, resulting in changes in maternal physiology and behaviour that help the mother cope with the new demands of pregnancy, childbirth and lactation. Hence, ...
Woo Chit Shing Jackson - - 2011
Ochratoxin A (OTA) is one of the most frequent mycotoxins detected in human blood worldwide. Apart from its well known nephrotoxicity, OTA-induced teratogenicity and carcinogenicity proven in animals are potential effects also in humans. Pregnant women have been exposed to this food contaminant via dietary exposure in a continuous and ...
Kennaway David J - - 2011
Circadian rhythms impact on a wide range of physiological systems and this impact extends to fertility, such that disruptions to timing systems can impact upon reproductive capacity. This is highlighted most obviously in mutant mouse models whereby deletion or mutation of single genes results not only in disrupted circadian rhythmicity, ...
Carlomagno G - - 2011
Diet is a critical factor for the development of both embryo and fetus, as well as maternal health. In particular, two natural molecules have been shown to exert beneficial effects on fertility, pregnancy wellness and embryo development: myo-inositol and melatonin, whose requirements increase during pregnancy. In the present review, we ...
Su Yi-Ju - - 2011
OBJECTIVE: To investigate the effect of pregnancy on the pulse wave of the mother. PATIENTS AND METHODS: Pulse waveforms recorded via a pulse oximeter from the left index finger of non-pregnant women and pregnant women in the three trimesters of pregnancy were Fourier transformed into power spectra. Spectral indices of ...
Swelum A A - - 2011
The objective of this work was to evaluate the possibility of substituting glycerol for ethylene glycol when cryopreserving buffalo semen. Semen of eight buffalo bulls was mixed, pooled, and frozen in one of these four diluents: centrifuged Tris egg yolk glycerol; centrifuged Tris egg yolk ethylene glycol; centrifuged Milk egg ...
Bazer Fuller W - - 2011
I became interested in biology as an undergraduate in a premedical curriculum but developed a passion for the field of reproductive biology because of a course in physiology of reproduction taken to meet requirements for admission to veterinary school. My career path changed, and I entered graduate school, obtained the ...
Benagiano Giuseppe - - 2011
Information on early embryo wastage is relevant for debating the status of human embryos. Two main points of view confront each other. Theists hold that human embryos should be treated as human persons from the moment of conception because, even accepting that human beings are the fruit of evolution, they ...
Papacleovoulou Georgia - - 2010
Nuclear receptor signalling is essential for physiological processes such as metabolism, development, and reproduction. Alterations in the endocrine state that naturally occur during pregnancy result in maternal adaptations to support the feto-placental unit. A series of studies have shown that nuclear receptor signalling is involved in maternal adaptations of bile ...
Galbally Megan - - 2010
To undertake a systematic review of the effects of exposure to mood stabilizer medication in pregnancy, evaluating teratogenicity and other outcomes for mother and child. This was one of three concurrent systematic reviews of psychotropic medication exposure in pregnancy. A systematic search was carried out of electronic databases, reference books ...
Fekete Andrea - - 2011
Plasma volume (PV) expansion is required for optimal pregnancy outcomes; however, the mechanisms responsible for sodium and water retention in pregnancy remain undefined. This study was designed to test the "arterial underfill hypothesis" of pregnancy which proposes that an enlarged vascular compartment (due to systemic vasodilation and shunting of blood ...
Yang Weili - - 2010
Hypoxia in pregnancy may induce fetal growth restriction and cause functional abnormalities during development. The present study determined the long-term influence of hypoxia in fetal life on dipsogenic behavior linked to central angiotensin (Ang) network in the offspring rats. Fetal blood pO(2) and body weight were decreased by hypoxia during ...
Schrier R W - - 2010
There are several mysteries about the normal physiology of pregnancy (1). Renal sodium and water reabsorption occurs despite an increase in total blood volume. Moreover, the renin-angiotensin-aldosterone system (RAAS) is also stimulated in normal pregnancy, even though an increase in total blood volume normally suppresses the RAAS and increases sodium ...
Cacciatore Alessandra - - 2010
Pregnancy can affect the lower genitourinary tract through physiologic changes, or traumatic injury tissue stretching and tearing, besides neurologic and vascular compression and compromise, and muscle strain are inevitable during childbirth.The levator ani complex of the pubococcygeus, puborectalis, and iliococcygeus muscles must allow passage of the fetus. The perineal body ...
Sasser Jennifer M - - 2010
It has been suggested that the phosphodiesterase-5 (PDE5) inhibitor sildenafil may be useful in the treatment of hypertension during pregnancy. However, we have reported a selective increase in renal inner medullary PDE5 that participates in the sodium retention of pregnancy. Therefore, the purpose of this study was to determine whether ...
Fonti Ylenia - - 2009
Pelvic-perineal dysfunctions, are the most common diseases in women after pregnancy. Urinary incontinence and genital prolapsy, often associated, are the most important consequences of childbirth and are determined by specific alterations in the structure of neurological and musculo-fascial pelvic support.Causation is difficult to prove because symptom occur remote from delivery.Furthermore ...
Guan Junchang - - 2009
The renin-angiotensin system (RAS) has an important role in cardiovascular homeostasis. This study determined the influence of water deprivation during pregnancy on the development of the RAS in rats, and examined blood pressure (BP) in the adolescent offspring. Pregnant rats were water deprived for 3 days at late gestation, and ...
Adam Gamal K - - 2009
OBJECTIVE: To investigate maternal and perinatal outcomes when pregnant women with visceral leishmaniasis (VL, also known as kala-azar) are treated with the antimonial sodium stibogluconate. METHOD: Forty-two pregnant women with VL were treated with sodium stibogluconate at Gadarif Hospital, Gadarif, Sudan, and mother and child were followed up for 1 ...
Bermúdez-Millán Ángela Á Connecticut NIH EXPORT Center of Excellence for Eliminating Health Disparities among Latinos, Center for Community Nutrition, Hispanic Health Council, Hartford, Connecticut, USA. - - 2009
Proper nutrition during gestation is important to prevent adverse pregnancy outcomes. Eggs contain many important nutrients necessary for fetal development and human survival. Three focus groups were conducted with Latina women living in Connecticut to identify cultural beliefs toward egg consumption during pregnancy, traditional egg dishes, and methods of preparation. ...
Ruamrak C - - 2009
Acne vulgaris impairs the appearance of an individual and causes psychological irritation. Inflammatory acne lesion is caused by multifactor incorporates in each step of acne pathogenesis. In an attempt to archive inflammatory lesion treatment with the promise of prevention of acne vulgaris, randomized and double-blind studies on the comparison of ...
Escher Geneviève - - 2009
Aldosterone is a key regulator of electrolyte and water homeostasis and plays a central role in blood pressure regulation. Hormonal changes during pregnancy, among them increased progesterone and aldosterone production, lead to the required plasma volume expansion of the maternal body as an accommodation mechanism for fetus growth. This review ...
Adair C D CD Section on Maternal-Fetal Medicine, Department of Obstetrics & Gynecology, The Wake Forest University School of Medicine, Winston Salem, NC, USA. - - 2009
Elevated blood levels of endogenous digitalis-like factors (EDLF) may decrease erythrocyte sodium pump activity in preeclampsia. As the highest EDLF levels might be expected in severe preeclampsia, we investigated sodium pump activity in that group of patients. Erythrocyte sodium pump activity was determined by (86)Rubidium uptake (in nM per hour ...
Waters Thaddeus P - - 2008
OBJECTIVE: This study was undertaken to characterize the course of bacterial vaginosis in pregnancy and to discern the bacterial morphotypes responsible for infection. STUDY DESIGN: Vaginal secretions were obtained in each trimester of pregnancy and were evaluated for bacterial vaginosis by Gram stain, categorized as normal or any of the ...
Afoakwa Emmanuel Ohene - - 2008
Chocolate characters not only originate in flavor precursors present in cocoa beans, but are generated during post-harvest treatments and transformed into desirable odor notes in the manufacturing processes. Complex biochemical modifications of bean constituents are further altered by thermal reactions in roasting and conching and in alkalization. However, the extent ...
Lan C C 1Infertility Center, Qilu Hospital, Shandong University, Jinan, 250012, - - 2008
To evaluate mesometrial transplantation of frozen-thawed ovarian tissue in rabbit and to choose the optimized fertilization method for oocytes retrieved from grafts by investigating the capability of oocyte fertilization and further development. Forty rabbits were divided into three groups randomly: control group, fresh tissues transplantation group and frozen-thawed tissues transplantation ...
Hård Anna-Lena - - 2008
Blockage of the renin-angiotensin system (RAS) during pregnancy is known to cause serious dysfunction of many organs of the foetus and newborn. Angiotensin II is an angiogenic factor and angiotensin-converting enzyme (ACE) inhibitors prevent retinal neovascularisation and their use in preventing proliferative retinopathy of prematurity has been suggested. We report ...
Coulthurst Sarah J - - 2008
Erwinia carotovora subsp. atroseptica is an enterobacterial phytopathogen causing economically significant soft rot disease. Pathogenesis is mediated by multiple secreted virulence factors, many of which are secreted by the type II (Out) secretion system. DsbA catalyzes the introduction of disulfide bonds into periplasmic and secreted proteins. In this study, the ...
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