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Results 301 - 350 of 367
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Mitchell M D - - 1987
The formation of arachidonate lipoxygenase products by uterine and intrauterine tissues of sheep in the last third of gestation has been evaluated. Maternal and fetal cotyledon, myometrium and fetal membrane exhibited evidence of arachidonate 5-, 12-, and 15- lipoxygenase activities. The major lipoxygenase product formed by fetal membrane and fetal ...
Milley J R - - 1987
The goal of this study was to test the hypothesis that the rate of fetal protein synthesis decreases during fetal hypoxia. Catheters were inserted into 13 sheep fetuses under maternal spinal and local fetal anesthesia. Five days after surgery, an infusion of L-[1-14C]tyrosine (0.05-0.25 muCi/min) was begun. Measurements were first ...
Vintzileos A M - - 1987
The value of the fetal biophysical profile in determining fetal well-being has been well documented. The increasing clinical use of the fetal biophysical profile, however, has led to the recognition of frequent errors in the interpretation and application of this modality. These errors may result in unnecessary interventions or adverse ...
Pic P - - 1986
Decapitation performed at days 17-18 leads to a drastic drop (82%) in blood TSH of 19 and 21-day-old rat fetuses below the mother's level. 125I-TSH injected at 21 days into the mother's bloodstream is not found in fetal blood. The fetal hypophysis is the main source of fetal plasmatic TSH.
Yano F - - 1986
It is often impossible to determine the presence of the fetal QRS waves from leads on the maternal abdomen because the amplitude is small or noise interferes. Yet, clinically, confirmation is highly necessary. Clinicians face a great difficulty when the fetal QRS waves are not identifiable: when, for example, they ...
Bowen L W - - 1986
The purpose of this study was to determine if interpretation of fetal scalp pH values would be enhanced by concurrent measurement of maternal venous pH. The last fetal capillary pH obtained before delivery was compared with simultaneous maternal-fetal pH difference as predictors of neonatal outcome assessed by five-minute Apgar scores. ...
Ponto J A - - 1986
Fetal dose estimates from Tc-99m MAA and Tc-99m DTPA aerosol were calculated using two methods. These calculations show that the average fetal dose decreases as gestational age (or fetal size) increases. Although the resultant dose estimates exceed those previously reported by severalfold, the risk to mother and fetus from undiagnosed ...
Murray H G - - 1986
The fetal electrocardiogram (FECG) has been recorded from 155 women in labor using a fetal scalp electrode and a minicomputerized enhanced averaging technique. Fetal hypoxia, acidosis, and stress have been diagnosed by analysis of blood from the fetal scalp, and post delivery from full gas analysis from blood taken from ...
Huikeshoven F J - - 1985
To better understand the fetal circulation and its regulation we constructed a dynamic model of fetal circulation as a transport system. The fetal vascular system is divided into 16 compartments which incorporate the peculiarities of the fetal circulation that produce a difference in oxygen concentration in blood supplying the upper ...
Philipps A F - - 1985
Hyperglycemia in fetal sheep has been shown to increase the fetal metabolic rate. Fetal venous glucose infusion was performed in eight late gestation, chronically catheterized fetal lambs to assess any changes in substrate uptake by the ovine uterus and conceptus. Fetal glucose infusion (11.9 +/- 0.6 mg glucose X kg-1 ...
Philipps A F - - 1985
Maternal or fetal substrate infusions into chronically catheterized fetal lambs have recently been performed in order to examine the effects of excessive fetal substrate presentation on fetal metabolism and metabolic rate. The degree of maternal hyperglycemia in this animal model has been shown to relate to the degree of fetal ...
Moore E S - - 1985
During intrauterine life, fetal mineral accretion depends on active transfer from mother to fetus by the placenta. To evaluate the role of fetal production of 1,25-dihydroxyvitamin D in regulation of fetal phosphorus, calcium, and parathyroid homeostasis, studies were performed in ewes and their fetal lambs. Fetal nephrectomy caused a rise ...
Meschia G - - 1985
The supply of O2 to fetal tissues depends upon a balance between factors that favor and hinder fetal oxygenation. Experiments in sheep have demonstrated that high rates of placental perfusion, high O2 affinity of fetal red cells and high rates of perfusion in fetal tissues compensate for an ineffective placental ...
Saini V D - - 1985
This paper describes a method for detecting low-level fetal ECG signals in maternal abdominal ECG recordings. Detection is based on a systematic application of the principle that the fetal ECG contains proportionately greater high-frequency components than does the maternal ECG. Adaptive subtraction of the maternal high-frequency components is used to ...
Singh N P - - 1984
In order to correlate the induction of sister-chromatid exchanges (SCE) to biological endpoints, and elucidate aspects of this relationships, 7,12-dimethylbenz[a]anthracene (DMBA) and methyl methanesulfonate (MMS), chemicals with different biological actions at different stages in development, have been evaluated for their ability to induce SCE at different gestational ages in the ...
Wallenburg H C - - 1984
Equatorial compression of the fetal head is known to occur during labor; its effect on trancutaneous scalp PO2 (PtCO2) was investigated in acute experiments in four fetal lambs. Fetal PtCO2, and oxygen tension (PaO2) and flow in a carotid artery were continuously measured. Equatorial head compression was obtained by inflating ...
Edelstone D I - - 1984
I have described how various maternal and fetal conditions can affect fetal oxygen delivery. It is clear from much of the recent experimental evidence that fetal oxidative metabolism can be sustained despite reductions in fetal O2 delivery of 40-50%. As long as fetal oxygen reserves are not depleted, fetal metabolic ...
Philipps A F - - 1984
Hyperglycemia has been shown to induce arterial hypoxemia in the chronically catheterized fetal sheep. To investigate the mechanism behind this glucose-induced hypoxemia, eight pregnant ewes and their fetuses were studied. Fetal glucose infusion (11.9 +/- 0.6 mg glucose/kg per min) was associated with a doubling of the fetal plasma glucose ...
Müller G - - 1984
Examination of 28 agitated, hyperventilating patients with fetal tachycardia showed that the mothers were in a hyperventilation-related state of hypocapnia and alkalosis. The mean maternal pCO2 was 17.48 +/- 6.79 mm Hg, the pH 7.54 +/- 0.14, which caused a reflex spasm of the umbilical veins, fetal acidosis and fetal ...
Hill L M - - 1984
Scalp sampling to evaluate fetal acid-base status was introduced 20 years ago. In most instances, adequate samples may be obtained without difficulty. Occasionally, however, a region of scalp free of hair cannot be found. As a result, the sample either diffuses along the hairs that are present or clots. Although ...
Kimura N - - 1983
Colony formation by multipotent hemopoietic precursors (CFUMIX) from human fetal liver was studied in a methylcellulose culture system containing erythropoietin (Ep) and media conditioned by leukocytes in the presence of phytohemagglutinin (PHA-LCM). The 15 fetal livers used were obtained from 13-23-week-old abortuses. Morphologic characteristics of the fetal mixed colonies were ...
Lev-Gur M - - 1983
The sonographic picture of fetal cyclopia at 33 weeks' gestation consists of a small fetal head, a central cavity replacing the cerebral lateral ventricles, lack of midline structures, absence of hemispheral vascular pattern and hydramnios. In addition, in our case a structure projecting from the fetal face correlated well with ...
Reppert S M - - 1983
Deoxyglucose labeled with carbon-14 was used in studying the utilization of glucose in the suprachiasmatic nuclei of fetal rats. The results showed that an entrainable circadian clock is present in the suprachiasmatic nuclei during fetal development and that the maternal circadian system coordinates the phase of the fetal clock to ...
Mueller-Heubach E - - 1983
Two patients with sonographically documented fetal ascites are described. Workup for immunologic or nonimmunologic causes was negative. Subsequent sonar examinations demonstrated disappearance of fetal ascites. At delivery, previous abdominal distention was apparent. Fetal ascites of unknown etiology in the late second trimester does not necessarily have a poor prognosis. Serial ...
O'Brien W F - - 1983
Prostaglandins have been detected in high levels in the fetal circulation. These substances are known to cause marked changes in the fetal and uterine circulations. The present study demonstrated an increase in fetal and maternal circulating levels of i prostaglandin F2 alpha in fetal lambs with acute acidosis. Both levels ...
Lebowitz R L - - 1983
Maternal ultrasonography makes it possible to easily detect hydronephrosis in the fetus, and therefore fetal "screening" should be part of every obstetrical ultrasonogram. However, the mere presence of fetal hydronephrosis virtually never means that either fetal intervention or early delivery is warranted. The importance of fetal case-finding is that it ...
Momma K - - 1983
Transplacental fetal ductal constriction was studied for 24 NSAIDs in full-term pregnant rats. All 16 acidic NSAIDs constricted the fetal ductus, but considerable differences in the grade of effect were noticed with the clinical doses of each NSAID. Six of the eight basic NSAIDs did not constrict the fetal ductus. ...
Rayburn W F - - 1982
The monitoring of fetal motion in high-risk pregnancies has been shown to be worthwhile in predicting fetal distress and impending fetal death. The maternal recording of perceived fetal activity is an inexpensive surveillance technique which is most useful when there is chronic uteroplacental insufficiency or when a stillbirth may be ...
Mackenzie T B - - 1982
Advances in fetal monitoring and research linking events in utero with subsequent fetal morbidity are elucidating the effects of maternal behavior on fetal well-being. Progress in these areas will generate medical and legal questions about the physicians' role in detecting and managing maternal behavior that threatens fetal well-being. These issues ...
Jaskoll T - - 1982
Recently it was suggested that some cases of premature closure of the sagittal suture in humans may be due to fetal head constraint. Using various modifications of the procedure for long-term shell-less cultivation of chick embryos, we sought to test the hypothesis that fetal head constraint may result in abnormalities ...
Ogburn P L PL - - 1982
Synchronized direct current (DC) cardioversion was used successfully for treatment of a pharmacologically refractory supraventricular tachycardia during pregnancy. No maternal or fetal complications or ill effects occurred. Although few cases have been reported, a review of the literature supports the use of synchronized DC countershock therapy for the treatment of ...
Moss M L - - 1982
The data above, and the literature reviewed, demonstrate that in 4 significant morphological characteristics the neuro-skeletal topology of the human basicranial regions is unique, and does not resemble that of any extant non-human primate at any fetal or postnatal age. These characteristics are: 1. the shape of the cranial base; ...
Löfgren O - - 1981
Continuous transcutaneous oxygen (PtcO2) monitoring is a noninvasive technique for recording changes in central oxygenation. PtcO2 monitoring has been for some years a routine method in neonatal and adult intensive care. The technique is a potential tool in fetal surveillance during labor. Some recently published studies which have been critical ...
Sampaio L O - - 1981
The changes of sulfated mucopolysaccharides and mucopolysaccharidases during bovine fetal development were analyzed. It is shown that chondroitin sulfate C increases in concentration up to the 50th day of fetal development and then decreases progressively until its complete disappearance in most adult tissues. Likewise, hyaluronidase also reaches a peak on ...
Link M P - - 1981
Fetal-like erythropoiesis frequently accompanies marrow stress conditions such as Diamond-Blackfan syndrome and aplastic anemia. In contrast, patients with transient erythroblastopenia of childhood have erythrocytes which lack fetal characteristics at the time of diagnosis. This report describes nine children with transient erythroblastopenia of childhood in whom transient, fetal-like erythropoiesis was observed ...
Sara V R - - 1981
A radioreceptor assay utilizing human fetal brain plasma membrane as matrix and somatomedin A as ligand (fetal brain RRA-SMA) was developed. Increased levels of fetal brain RRA-SMA were found in the fetal circulation. The concentration was approximately 4-fold higher in the fetal as compared to the adult human. At birth, ...
Wagner P G - - 1981
Measurement of fetal scalp pH can aid in the detection of fetal acidosis. In order to evaluate fetal status further and possibly reduce fetal and neonatal mortality and morbidity, as well as reduce unnecessary cesarean section, continuous assessment of fetal pH is being investigated. Discussion of a six-month experience with ...
Goodlin R C - - 1981
This case report of fetal asphyxia and related studies suggest that fetal endorphins play a role in fetal pain tolerance and cardiovascular asphyctic responses. Elevated fetal endorphin levels may, like narcotics, produce abnormally "flat" fetal heart rate patterns intrapartum and fetal tolerance to pain. Although naloxone hydrochloride was used with ...
Melnick M - - 1981
Using three congenic strains, C57BL/10Sn(H-2b), B10.A/SnSg(H-2a), and B10.D2/nSn(H-2d), we sought to investigate the possible association of H-2 haplotype with the number of implants, fetal survival, and fetal weight, as well as to analyze the possible effects of hybrid vigor and maternal-fetal histoincompatibility in primigravidae mice. The results of this study ...
Cowan D B - - 1980
Fetal distress is defined. The pathophysiology of fetal distress is discussed and tretment is recommended. The principles of intrapartum fetal resuscitation are proposed, with particular reference to the inhibition of uterine activity.
Ron M - - 1980
Two cases of uncomplicated fetal baseline tachycardia in postterm pregnancies that resulted in fetal death are reported. The tachycardia was the only sign of fetal distress in both cases. Although the condition is not usually considered and ominous sign of fetal outcome, the authors recommend immediate cesarian section in postterm ...
Graham J M JM - - 1980
Two instances of metopic craniosynostosis provide dramatic experiments of nature which implicate fetal head constraint as one cause of early sutural fusion. The presumed restriction of growth stretch at the metopic suture in one instance was due to a bicornuate uterus in which the fetal head was markedly constrained. The ...
Freedman L J - - 1980
A case is reported of fetal survival after maternal listeremia. Transplacental fetal infection may have been prevented by early delivery. Review of the literature suggests that management be based on cultures of the maternal and fetal compartments. We believe that the considerations for immediate delivery as opposed to medical therapy ...
Arias J W - - 1980
An instance of fetal intestinal obstruction uncovered during serial sonography in a pregnancy complicated by previous jejunoileal bypass is discussed. The presence of abnormal cystic structures with a gravity-dependent sediment layering effect within the fetal abdomen provided a useful, and possibly specific, sign in the diagnosis of fetal gastrointestinal obstruction.
Gogolák-Oláh E - - 1979
Comparative studies on three-dimensional models give new possibilities in examination of the internal and external evolution of the thymus, phenomena that occur concomitantly with the histogenesis of the organ during the fetal life period. During the antenatal period, the invasion and burgeoning of capillaries represent a strong potential of biostimulation ...
Maynard D E - - 1979
The monitoring of fetal EEG during labour can assist in identifying the effects on the fetus of anaesthetic and other drugs administered to the mother. Additionally it assists in detecting inadequate cerebral perfusion. One unsuccessful and one successful method are described of removing fetal EKG from the fetal EEG signal, ...
Young B K - - 1978
Fifty-one women in labor had continuous monitoring of fetal scalp tissue pH, fetal heart rate by ECG, and uterine contractions. A miniature pH electrode secured by a double spiral fetal ECG electrode was used for measurement of fetal pH every 15 seconds. The results were correlated with fetal scalp blood ...
LaMont J T - - 1978
Microsomal galactosyltransferase activity of fetal rat colon increased fourfold between 18 and 22 days of gestation and then more slowly during neonatal life reaching adult levels after 14 days. The Km for uridinediphosphate- (UDP) galactose, pH optimum, cation, and detergent requirements were identical in fetal and adult galactosyltransferase. Cytidine 5'-diphosphate-choline ...
Biehl D - - 1978
To investigate whether fetal acidosis increases the placental transfer of lidocaine, resulting in higher fetal blood levels of the drug, lidocaine was infused intravenously into ten pregnant ewes to maintain plasma levels of 2-4 microgram/ml. After maternal-fetal equilibrium was reached, the fetus was made acidotic by infusing lactic acid intravenously. ...
Lauersen N H - - 1978
Microfilming of fetal monitoring records has, at our institution, been found to be a practical method for storage of recording papers from fetal monitoring. This system permits a reduction of the records by a factor of 20:1 and up to 7.64 hours of fetal monitroing records will fit into a ...
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