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Results 201 - 250 of 410
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Strasburger Janette F - - 2005
Life-threatening fetal arrhythmias are rare and warrant sophisticated specialty prenatal care, often provided by maternal-fetal medicine obstetricians, and pediatric and adult cardiologists. This medical field is in quick transition, and new methods of diagnosis and treatment of the fetus with arrhythmias are emerging. In this article, the mechanisms of arrhythmias ...
Keswani Sundeep G - - 2005
OBJECTIVES: There are shifts in fetal hemodynamics during open fetal surgery that were not appreciated until the use of intraoperative fetal echocardiography. We have developed an intraoperative monitoring strategy to continuously assess fetal hemodynamics. We hypothesized that this approach would enhance intraoperative management and survival. METHODS: Medical records of open ...
Dildy Gary A GA - - 2005
The principal purpose of intrapartum fetal assessment is to detect hypoxemia-ischemia, which may lead to fetal jeopardy. A quarter century ago, electronic fetal monitoring replaced intermittent auscultation as the primary method of intrapartum fetal assessment in the United States. It seems that electronic fetal monitoring will continue to be the ...
Agrawala Geetika - - 2005
An isolated fetal ascites is a rare ultrasonographic finding. It is commonly diagnosed in association with fetal genitourinary or gastrointestinal conditions, mainly bowel obstruction. We present the sonographic features and neonatal outcome of a fetus with a large bowel obstruction, perforation and subsequent development of meconium peritonitis, prenatally diagnosed as ...
Sebe Philippe - - 2005
BACKGROUND: The aim of the study was to investigate the development of the human urethral sphincter complex during fetal development. METHODS: 23 human male fetal specimens were investigated. The histological sections were processed according to the epoxy resin-based plastination technology. RESULTS: At 9th week of gestation, a combined sphincteric primordium ...
Ellison Peter T - - 2005
The fetal origins hypothesis, or Barker hypothesis, is both stimulating and challenging for evolutionary human biologists. While evidence of a correlation between conditions around the time of birth and later health outcomes has been presented before, the more recent evidence of a connection between fetal growth and chronic disease risk ...
Robinson Julian N - - 2004
BACKGROUND: Antenatal surveillance is inefficient for accurately detecting fetal compromise. A noninvasive technique for assessing fetal metabolic status would be useful for clinical management. CASE: Fetal magnetic resonance spectroscopy was performed at 20 weeks in a pregnancy complicated by severe intrauterine growth restriction to determine if lactate, a metabolite associated ...
Harrison Michael R - - 2004
Today, the Fetal Treatment Center at the University of California, San Francisco is premier not only for its innovative and cutting-edge developments in fetal diagnosis and therapy, but in its delivery of excellent clinical care to patients from within and outside the United States. Indeed it is recognized as the ...
Singh Gautam K. - - 2004
Fetal tachyarrhythmias are an important cause of fetal morbidity and mortality. The majority of fetal tachyarrhythmias are due to atrioventricular reentrant type of supraventricular tachycardia and atrial flutter. Fetal echocardiography remains the main tool of diagnosing and discerning the mechanism of tachyarrhythmia. The goals of therapy for fetal arrhythmias are ...
Myers Laura B - - 2004
Fetal intervention for certain life-threatening conditions has progressed from being primarily experimental in nature to the standard of care in certain circumstances. While surgical techniques have advanced over the past few years, the anaesthetic goals for these interventions have remained the same; namely, minimizing maternal and fetal risk as well ...
Low James A - - 2004
This chapter documents the growing evidence of the occurrence and significance of antepartum fetal asphyxia. Perinatal mortality studies demonstrate that the majority of fetal deaths, including those due to asphyxia, occur in the antepartum period. Epidemiological studies of cerebral palsy conclude that a minority of cases of cerebral palsy are ...
Cox P Boris W - - 2004
PURPOSE OF REVIEW: Refined techniques and skills have enabled sophisticated prenatal diagnosis in utero and resulted in the newly evolving specialty of fetal surgery in a few centres worldwide. Most of the procedures performed today have been preceded by extensive experimental research in animals, whereas fetal anaesthesia is mainly based ...
Christensen Julie L - - 2004
The major site of hematopoiesis transitions from the fetal liver to the spleen and bone marrow late in fetal development. To date, experiments have not been performed to evaluate functionally the migration and seeding of hematopoietic stem cells (HSCs) during this period in ontogeny. It has been proposed that developmentally ...
Reuss James L - - 2004
Fetal pulse oximetry shares many problems with traditional pulse oximetry, but also poses unique challenges that may compromise accurate SpO2 determination and data availability. The purpose of this review is to characterize the factors that may influence fetal pulse oximetry and their relationship to sensor design. A review of the ...
Vrba J - - 2004
Accurate knowledge of the electromagnetic model of the fetal brain is required for quantitative fetal MEG (fMEG) signal analysis. The model is defined by the fetal head position, assuming that volume currents are confined to it. Head position can be located by 3D ultrasound. Since the ultrasound is presently not ...
Ishii Keisuke - - 2003
At 26 weeks of gestation, fetal tachyarrhythmias (about 250 bpm) and ascites were detected by ultrasonography, and oral treatment with propranolol (30 mg/day) was commenced. Within 10 h, the fetal heart rate changed to approximately 85 bpm. The averaged fetal magnetocardiogram triggered by R peaks showed P wave and QRS ...
Valensise H - - 2003
The recent efforts in the study of fetal compartments could help us to a better recognition of the proper fetal growth and well being. Fat content correlates directly with energy stores. Fat mass and lean body mass is often used in the nutritional assessment of the individual. Moreover chromosomal abnormalities ...
Schmidt Stephan - - 2003
The newly available modified laserspectroscopy for fetal physiologic measurements provides information about biochemical parameters and is potentially an additional technique for fetal surveillance. METHOD: Using laserspectroscopy it was possible to trace changes in absorbances at four different wavelengths and to calculate relative changes of HbO2, desaturated haemoglobin, total haemoglobin, and ...
Olofsson Per - - 2003
Two randomized controlled trials (RCT) on intrapartum fetal monitoring with cardiotocography (CTG) only versus CTG combined with automatic ST segment waveform analysis of the fetal ECG have been performed. In altogether 6826 randomized cases, the odds ratio for operative delivery for fetal distress (ODFD) was 0.65 (95% confidence interval 0.53-0.78) ...
Oi Shizuo - - 2003
It has been recognized that the morphological fetal CNS findings detected in early development are not always the final features: occasionally they may not be determined in diagnosis and may change developmentally or chronologically during the fetal life in utero. Certain factors of the fetal chronology of CNS anomalies can ...
von Koch Cornelia S - - 2003
Neonatal hydrocephalus is one of the most common congenital anomalies affecting the nervous system. Currently, ultrasonography allows for early detection of fetal ventriculomegaly and presents the family with several treatment options: termination of pregnancy, early delivery and neonatal shunting, and delivery at term followed by shunting. Despite ventricular decompression after ...
Van de Velde Marc - - 2003
PURPOSE OF THE REVIEW: The present manuscript reviews recent data on fetal intrapartum surveillance with special attention to new technologies. RECENT FINDINGS: Continuous fetal heart-rate monitoring, fetal blood sampling, intrapartum stimulation tests, fetal pulse oximetry and fetal electrocardiography will be reviewed. SUMMARY: From the available data it appears that to ...
Cole Charles - - 2003
Admission electronic fetal monitoring did not decrease neonatal morbidity and mortality compared with intermittent auscultation. Patients in the admission fetal monitoring group were more likely to receive continuous electronic monitoring and fetal blood sampling, but there were no significant differences in the rates of operative deliveries or episiotomy. Institutions not ...
Luttkus Andreas K - - 2003
BACKGROUND: Fetal pulse oximetry measures arterial oxygen saturation during delivery. The fetal electrocardiogram STAN S21 analyzes the repolarisation segment of ECG (ST) waveform, which is altered by the intramyocardial potassium release resulting from metabolic acidemia. This study aimed to evaluate the feasibility of a simultaneous application of pulse oximetry and ...
Graf Joy L - - 2003
Advances in prenatal diagnosis including improvements in ultrasonography have revealed the natural history of fetal sacrococcygeal teratomas, and this natural history differs substantially from that for postnatally diagnosed sacrococcygeal teratoma. A fetal sacrococcygeal teratoma may lead to perinatal morbidity and mortality by a variety of mechanisms. Adverse clinical sequelae of ...
Hosono Takayoshi - - 2002
OBJECTIVE: To demonstrate the coincidence of fetal magnetocardiography (FMCG) and fetal direct electrocardiography (FDECG) in a case of fetal atrial flutter (AF). METHODS: FMCG and FDECG using a fetal scalp electrode were recorded in the case of fetal AF at 41 weeks' gestation. RESULTS: FMCG revealed fetal AF with 2:1 ...
Chervenak Frank A - - 2002
The transition from innovation to standard of care for fetal surgery should be guided by ethical considerations. We provide an ethical framework that identifies criteria for the investigation of fetal surgery. This framework addresses the initiation and assessment of clinical trials to determine whether they establish a standard of care, ...
Erdag Gulsun - - 2002
In this study, we tested a non-permeating cryoprotectant, trehalose, in combination with dimethyl sulfoxide (Me(2)SO) in the cryopreservation of human fetal skin and compared it to Me(2)SO and glycerol, protocols that are routinely used by skin banks. The viability of fetal skin from four groups (fresh, and cryopreserved with glycerol, ...
East Christine E - - 2002
This article examines the current status of fetal pulse oximetry (FPO) as a means of intrapartum assessment of fetal wellbeing. FPO has been developed to a stage where it is a safe and accurate indicator of intrapartum fetal oxygenation. In general, sliding the FPO sensor along the examiner's fingers and ...
Hosono Takayoshi - - 2002
A case of fetal atrial flutter successfully recorded by magnetocardiography (MCG) is reported. Initial ultrasonography revealed frequent fetal atrial extrasystoles at 31 weeks of gestation. Fetal MCG was recorded using a multichannel MCG system at 31, 35 and 38 weeks of gestation. A series of fluctuations in the baseline of ...
Cauldwell Charles B - - 2002
Fetal surgery is the antenatal treatment of fetal malformations that cannot be adequately corrected after birth. Anesthesia for fetal surgery involves two patients, and issues of maternal safety, avoidance of fetal asphyxia, adequate fetal anesthesia and monitoring, and uterine relaxation are important. Communication with the surgeon to determine the surgical ...
Rijnders R J P - - 2002
OBJECTIVES: Fetal pulse oximetry was performed during labor in high-risk cases for fetal distress to determine the diagnostic value of this method. METHODS: The fetal SpO2 values were blinded from the obstetrician so that these values did not influence clinical decisions. Mean and lowest SpO2 measurements for the last 30 ...
Park H W - - 2001
Congenital malformations are one of the main topics, which must be addressed in the 21st century. Fetal surgery is expected to become a routine procedure for malformed fetal patients in the near future. This paper presents some important aspects of the embryological background required for fetal surgery and shows normal ...
J. G. Stinstra,M. J. ...
this paper results in an additional peak in front of the QRS-complex in the magnetocardiogram measured in the 21 week of gestation. Apart from this finding the magnetocardiogram is normal. Thus, the diagnosis of this congenital disease cannot be confirmed by fetal MCG
Flake A W - - 2001
Ethical issues in maternal-fetal surgery require special consideration because of the often-conflicting interests of the mother and fetus. Over the past 2 decades an ethical framework for fetal therapy and maternal-fetal surgery has been developed. This framework continues to evolve as new procedures are developed and new controversies arise. The ...
Schwartz D A - - 2001
The EXIT (ex utero intrapartum treatment) procedure is used to maintain fetal-placental circulation during partial delivery of a fetus with a potentially life-threatening upper airway obstruction. We performed the EXIT procedure on a fetus with a large intra-oral cyst. Sevoflurane was used as the anesthetic because of its rapid titratability. ...
Hosono T - - 2001
We report a case of fetal Wolff-Parkinson-White (WPW) syndrome diagnosed prenatally by magnetocardiography (MCG). At 32 weeks' gestation, the fetus was diagnosed to have a paroxysmal supraventricular tachycardia by ultrasonography and direct fetal electrocardiogram (ECG). Transplacental fetal therapy by maternal oral administration of propranolol resolved the fetal tachyarrhythmia. Although the ...
Tan K H KH Department of Maternal Fetal Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, Singapore, 229899. - - 2001
Manual fetal manipulation has been suggested to improve the efficiency of antepartum fetal heart rate testing. The objective of this review was to assess the merits or adverse effects of the use of manual fetal manipulation in conjunction with tests of fetal wellbeing. We searched the Cochrane Pregnancy and Childbirth ...
Zourabian A - - 2000
Pulse oximetry (oxygen saturation monitoring) has markedly improved medical care in many fields, including anesthesiology, intensive care, and newborn intensive care. In obstetrics, fetal heart rate monitoring remains the standard for intrapartum assessment of fetal well being. Fetal oxygen saturation monitoring is a new technique currently under development. It is ...
Gratacós E - - 2000
Fetoscopy has consolidated its position in fetal medicine, thanks to a combination of insight into the pathophysiology of selected conditions that are amenable to fetal surgery and the technical innovations in endoscopic equipment. In clinical practice, two types of fetoscopy can be discerned: Obstetrical Endoscopy and Endoscopic Fetal Surgery. The ...
Quintero R A - - 2000
OBJECTIVE: Vesicoamniotic shunting may be difficult or impossible in selected cases of fetal lower obstructive uropathy. The purpose of this article is to describe the performance of fetal hydrolaparoscopy and endoscopic fetal cystotomy in two fetuses with complicated lower obstructive uropathy. STUDY DESIGN: Fetal hydrolaparoscopy-endoscopic fetal cystotomy was performed in ...
Jacques S L - - 2000
The possibility of optical oximetry of the blood in the fetal brain measured across the maternal abdomen just prior to birth is under investigation. Such measurements could detect fetal distress prior to birth and aid in the clinical decision regarding Cesarean section. This paper uses a perturbation method to model ...
Gogarten W - - 2000
Major improvements in the diagnosis and treatment of fetal malformations, including in-utero surgical repair, have occurred in the past decade. As opposed to anaesthesia for caesarean sections, a high placental drug transfer is warranted to provide adequate fetal anaesthesia and immobility, strongly favouring the use of general anaesthesia for these ...
Jibodu O A - - 2000
Intrapartum hypoxia was thought to contribute to the incidence of cerebral palsy, seizures and mental retardation. Electronic fetal monitoring was expected to prevent or reduce this incidence. Electronic fetal monitoring has a high false positive rate and fetal blood sampling, which is an invasive procedure, only allows an intermittent assessment. ...
Young A D - - 2000
A critical component in the conduct of a prenatal developmental toxicity study is the evaluation of fetal skeletal development. As the developing rodent fetus is typically evaluated at gestation day 20, at a time when ossification of the skeleton is incomplete, a thorough assessment of skeletal development would include both ...
Yam J - - 2000
Fetal pulse oximetry has been advocated as a means of improving the specificity of cardioto-cography in intrapartum fetal surveillance. The objective of this article, the first of two reviewing the current literature on fetal pulse oximetry, is to discuss the principles of this new and evolving technology, its development, and ...
Yam J - - 2000
Part II continues by discussing the clinical application of fetal pulse oximetry in intrapartum fetal surveillance as reviewed in the literature. It profiles the predictive ability of fetal pulse oximetry and its correlation with conventional methods of fetal monitoring. In addition, an account is made of its limitations, safety, and ...
Corda M - - 2000
Haemoglobin (Hb) J-Sardegna [alpha50(CE8)His-->Asp] is a haemoglobin variant characteristic of subjects from the island of Sardinia. Here we report a study of the functional properties of both fetal and adult Hb J-Sardegna. The results indicate that adult Hb J-Sardegna displays an oxygen affinity that is higher than that of adult ...
- - 2000
The goal of antepartum fetal surveillance is to prevent fetal death. Antepartum fetal surveillance techniques based on assessment of fetal heart rate patterns have been in clinical use for almost three decades. More recently, real-time ultrasonography and Doppler velocimetry have been used to evaluate fetal well-being. Antepartum fetal surveillance techniques ...
Maeda K - - 1999
We have presented that fetal surveillance may be enhanced by use of the fetal actocardiogram and by computerized processing of fetal motion as well as fetal B-mode ultrasound imaging. Ultrasonic Doppler fetal actogram is a sensitive and objective method for detecting and recording fetal movements. Computer processing of the actograph ...
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