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Derks Jan B JB Department of Perinatology, University Medical Centre, 100 3584 CX Utrecht, The - - 2010
In complicated labor, neonatal outcome may depend not only on the extent of fetal asphyxia and acidosis but also on the effects on the fetal cardiovascular system of reactive oxygen species (ROS) generated during the ischemia-reperfusion (I/R) associated with repeated compressions of the umbilical cord. This study tested the hypothesis ...
Boat Anne - - 2010
To lower the incidence and severity of fetal cardiovascular depression during maternal fetal surgery under general anesthesia. We hypothesized that supplemental intravenous anesthesia (SIVA) with propofol and remifentanil would lower the need for high-dose inhalational anesthesia and provide adequate maternal depth of anesthesia and uterine relaxation. SIVA technique would minimize ...
van Oppenraaij R H F - - 2010
For normal fetal growth and development a well-developed chorionic villous vascularization is essential. The aim of this study is to investigate whether idiopathic second trimester fetal loss is associated with an underdeveloped chorionic villous vascularization. 38 placentas after late miscarriage, classified as idiopathic fetal loss (IFL, n=16) or as fetal ...
Tongprasert F - - 2010
To describe systematic cordocentesis training among maternal-fetal medicine (MFM) fellows. During their 2-year training period, five MFM fellows, who had completed systematic model training, performed 1116 midpregnancy diagnostic cordocentesis procedures (mean, 223 (range, 185-259) procedures each) under expert supervision. The details of the procedures were recorded prospectively. Multiple pregnancies and ...
Deprest Jan A - - 2010
Fetal diagnosis prompts the question for fetal therapy in highly selected cases. Some conditions are suitable for in utero surgical intervention. This paper reviews historically important steps in the development of fetal surgery. The first invasive fetal intervention in 1963 was an intra-uterine blood transfusion. It took another 20 years ...
De Silva K Ranil D - - 2010
The purpose of this study was to examine the degree of contribution from the vertebrobasilar and carotid systems to the origin of the PCA in fetal autopsy brains of last trimester of pregnancy and to compare with published data on the configuration of adult and fetal brains in a population ...
Vullings R - - 2010
The use of the non-invasively obtained fetal electrocardiogram (ECG) in fetal monitoring is complicated by the low signal-to-noise ratio (SNR) of ECG signals. Even after removal of the predominant interference (i.e. the maternal ECG), the SNR is generally too low for medical diagnostics, and hence additional signal processing is still ...
Holzmann Malin - - 2010
We performed a follow-up national survey concerning intrapartum fetal surveillance in Sweden to investigate if routines had changed since a previous survey in 1999, due to new data that have emerged since and technical developments. All labor wards throughout Sweden, with sizes varying from around 350 to more than 9,000 ...
Raicević Sasa - - 2010
Our aim was to investigate the relation between fetal distress and oxidative stress. Fetal distress was associated with increased concentration of superoxide in the fetal blood and with significant increase of the level of H2O2 in both maternal and fetal blood. The activity of superoxide dismutase was increased roughly sixfold ...
Guo Rong - - 2010
The prevalence of cerebral palsy (CP) shows little temporal or geographic variation and is associated with preterm birth, maternal/fetal infection/inflammation, and fetal growth restriction (IUGR), a potential surrogate for chronic fetal hypoxemia (CHX). We previously demonstrated CHX causes a fetal inflammatory response syndrome (FIRS). Herein, we test the hypothesis that ...
Kohl Thomas - - 2010
BACKGROUND: The availability of high-end endoscopic equipment, microcatheters, miniballoons, tiny laser fibers, and other devices has been instrumental in the development of minimally invasive fetoscopic interventions. These interventions are performed for a spectrum of fetal disease states that progress in severity over the course of gestation and have a huge ...
Cleal J K - - 2010
OBJECTIVE: To investigate whether a noninvasive fetal electrocardiography (fECG) system can identify cardiovascular responses to fetal hypoxaemia and validate the results using standard invasive fECG monitoring techniques. DESIGN: Prospective cohort study. SETTING: Biological research facilities at The University of Southampton. POPULATION OR SAMPLE: Late gestation ovine fetuses; n = 5. ...
Czabanski Robert - - 2010
Cardiotocography (CTG) is a biophysical method of fetal condition assessment based mainly on recording and automated analysis of fetal heart activity. The computerized fetal monitoring systems provide the quantitative description of the CTG signals, but the effective conclusion generation methods for decision process support are still needed. Assessment of the ...
Myatt Leslie - - 2010
The fetal membranes fulfill several functions during pregnancy. In addition to containing the products of conception and amniotic fluid, they presumably have barrier functions and fulfill paracrine signaling functions between the maternal (decidual) and fetal compartments. As the membranes are in an ideal place to receive both maternal and fetal ...
Romano Maria - - 2010
In this paper we describe an Italian experience of fetal home monitor, organized using a portable phonocardiography system (product by Pentavox, Hungary), and the method utilized to evaluate its effectiveness in providing quality services and patient satisfaction. Patient satisfaction is an important dimension in the evaluation of quality care delivery. ...
Ayres Allen W - - 2010
Background. A prenatally diagnosed fetal anomaly that could compromise the fetal airway at delivery can be managed safely with the ex utero intrapartum treatment (EXIT) procedure. Case. A 26-year-old healthy primigravida was diagnosed during her midtrimester anatomic ultrasound survey with a fetal oropharyngeal cystic structure located at the base of ...
Ayres-de-Campos Diogo - - 2010
Intrapartum fetal hypoxia remains an important cause of death and permanent handicap and in a significant proportion of cases there is evidence of suboptimal care related to fetal surveillance. Cardiotocographic (CTG) monitoring remains the basis of intrapartum surveillance, but its interpretation by healthcare professionals lacks reproducibility and the technology has ...
Santos J E P JE Department of Animal Sciences, University of Florida, Gainesville FL 32611, USA. - - 2010
The establishment and maintenance of pregnancy in lactating dairy cows is a complex biological event that is influenced by a multitude of factors, from the reproductive biology of the cow to managerial aspects of the dairy farm. It is often mentioned in the scientific literature that fertility in dairy cows ...
Day M L ML Department of Animal Sciences, The Ohio State University, Columbus, OH 43210, USA. - - 2010
Estrous synchronization and timed ovulation programs that permit AI at a predetermined time (timed AI) rather than as determined by detection of spontaneous estrus are requisite for increased adoption of AI in the beef cattle industry. In the past two decades, significant progress has been achieved in developing programs that ...
Akimoto Shimpei S Graduate School of Engineering, Chiba University, Chiba 263-8522, Japan. - - 2010
Since the diversification of the electromagnetic (EM) environment is spreading, it is essential to estimate the EM energy absorption rate [specific absorption rate (SAR)] of a pregnant woman's body and her fetus under various exposure situations. For example, if pregnant women work in jobs where they might wear business portable ...
Cheek Theodore G - - 2009
This monograph will review and update our understanding of the administration of anesthesia for nonobstetric surgery and its maternal and fetal effects. It begins with a summary of the subject and a short review of maternal physiologic changes during pregnancy with an emphasis on their anesthetic implications. Attention will be ...
Reed Casey A - - 2011
Near-infrared spectroscopy (NIRS) has been shown to provide reliable noninvasive monitoring of regional oxygenation in a variety of clinical settings. We set out to test its feasibility as a monitor of fetal and placental oxygenation during fetal cardiac surgery. Six ovine fetuses from 98-110 ds gestation were placed on fetal ...
Prout Andrew P - - 2010
OBJECTIVE: We hypothesized that repetitive umbilical cord occlusions (UCOs) with worsening acidosis will lead to a fetal inflammatory response. STUDY DESIGN: Chronically instrumented fetal sheep underwent a series of UCOs until fetal arterial pH decreased to <7.00. Maternal and fetal blood samples were taken for blood gases/pH and plasma interleukin ...
Kotas M - - 2010
The noninvasive fetal electrocardiography is a source of more precise information on the fetal heart activity than the measurements based on Doppler ultrasound signals. However, the clinical diagnostic applications of this technique are limited by difficulty with successful detection of small amplitude fetal QRS complexes. In this study, we investigate ...
Younes A Saleh - - 2009
Several viruses can pass the maternal-fetal barrier, and cause diseases of the fetus or the newborn. Recently, however, it became obvious, that viruses may invade fetal cells and organs through different routes without acute consequences. Spermatozoa, seminal fluid and lymphocytes in the sperm may transfer viruses into the human zygotes. ...
Lowery Curtis L CL Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, 4301 West Markham Street, #518, Little Rock, AR 72205, USA. - - 2009
SQUID Array for Reproductive Assessment is a unique magnetoencephalography device designed for the noninvasive recording of fetal brain activity. In this article, we provide a general overview of the technology and its potential application to fetal medicine. A large number of studies that have been conducted and published describing this ...
Fratelli Nicola - - 2009
OBJECTIVE: The purpose of this study was to assess the interobserver reproducibility of transabdominal 3-dimensional (3D) fetal neurosonography. METHODS: This was a prospective observational study. We studied 23 consecutive singleton pregnancies between 18 and 23 weeks' gestation. All cases had normal fetal neurosonographic examination findings, which were confirmed after birth. ...
Adzick N Scott - - 2010
After more than two decades of experimental and clinical work, fetal surgery is an accepted treatment option for highly selected fetuses with life-threatening anomalies. Fetal lung masses associated with hydrops are usually fatal. These lesions can be resected in utero if they are predominantly solid or multicystic. Fetal sacrococcygeal teratoma ...
Hirose Shinjiro - - 2009
Fetal intervention for myelomeningocele (MMC) may improve hydrocephalus and hindbrain herniation associated with the Arnold-Chiari II malformation and may reduce the need for ventriculoperitoneal shunting. As of now, there is little evidence that prenatal repair of MMC improves neurologic function. MMC is the first nonlethal disease under consideration and study ...
Sekar Priya - - 2009
In this review, the authors explore the role of noninvasive and invasive fetal interventions in fetal cardiovascular disease guided by observations at fetal echocardiography. They first review fetal cardiac lesions that may be ameliorated by fetal intervention and then review noncardiac fetal pathologic findings for which fetal echocardiography can provide ...
Farley Darren - - 2009
Fetal monitoring during pregnancy is used to prevent fetal death. This article addresses the goals of fetal monitoring during pregnancy. Methods of fetal surveillance are reviewed, as well as the meaning of abnormal fetal testing and how these results relate to fetal and neonatal outcome. Overall, pediatricians who understand the ...
Jancelewicz Tim - - 2009
Over the past 3 decades, fetal surgery for congenital disease has evolved from merely a fanciful concept to a medical field in its own right. Techniques for open hysterotomy, minimal-access hysteroscopy, and image-guided percutaneous fetal access have become well established, first in animal models and subsequently in humans. At the ...
SÅ‚odki Maciej - - 2009
Primary fetal hydrothorax is a relatively rare disorder, occurring in 1 out of 15,000 pregnancies, but connected with high perinatal mortality. In the event of little or no progress of the effusion or stable clinical course, conservative management seems to be the most appropriate course of action. In nearly half ...
Kulkarni Makarand - - 2009
MRI is increasingly being used in the diagnosis of fetal anomalies suspected on USG. The USG evaluation of fetal spinal anomalies is limited by acoustic shadowing, fetal position and the amount of liquor. Fetal MRI is able to show spinal anomalies well, as in our case of fetal diastematomyelia with ...
Mao Caiping C Perinatal Biology Center, Soochow University School of Medicine, Suzhou 215007, - - 2009
Since the concept of fetal origins of adult diseases was introduced in 1980s, the development of the renin-angiotensin system (RAS) in normal and abnormal patterns has attracted attention. Recent studies have shown the importance of the fetal RAS in both prenatal and postnatal development. This review focuses on the functional ...
Odeh Marwan - - 2009
Although sonographic fetal sex determination is feasible in most pregnancies, in some cases, it may pose difficulties. An attempt to determine the fetal sex should not be made before 12-weeks' gestation because this early, it is relatively inaccurate. After 13 weeks, it is accurate in 99% to 100% of cases ...
Schiermeier Sven - - 2009
OBJECTIVE: To determine whether short time variation (STV) of fetal heart beat correlates with scalp pH measurements during labor. PATIENTS AND METHODS: From 1279 deliveries, 197 women had at least one fetal scalp pH measurement. Using the CTG-Player, STVs were calculated from the electronically saved cardiotocography (CTG) traces and related ...
Zhang Bo B Graduate School of Science and Engineering, Waseda University, Tokyo, Japan. - - 2009
The clinical target of this study is intrauterine patch coverage of fetal myelomeningocele. We propose a new surgical robotic system for intrauterine fetal surgery with patch-stabilizer and laser manipulator. The target disease of the fetal surgery is spina bifida or myelomeningocele, which is incomplete closure in the spinal column and ...
De Buck Frederik - - 2008
PURPOSE OF REVIEW: To look at different anesthetic approaches to different surgical techniques used in fetal procedures and the influence of maternal and fetal factors on anesthetic management. RECENT FINDINGS: Fetal surgery is evolving rapidly in the field of mainly ex-utero intrapartum treatment procedures, where new indications are found and ...
Limperopoulos Catherine C Fetal-Neonatal Neurology Research Program, Department of Neurology, Children's Hospital Boston and Harvard Medical School, Boston, MA, USA. - - 2008
The first objective of our study was to describe the prevalence and spectrum of posterior fossa anomalies over 5 years in a major fetal care center where the referral diagnosis (by fetal sonography) was investigated by fetal MRI and, if confirmed, by postnatal MRI if possible. The second objective was ...
Lv Juanxiu J Perinatal Research Laboratory, Soochow University School of Medicine, Suzhou, - - 2008
Previous studies have suggested that prenatal exposure to nicotine is associated with abnormal development in fetuses, including fetal brain damage. The present study determined the effect of maternal administration of nicotine during different gestational periods on brain nicotine receptor subunits in fetal rats. Subcutaneous injections of nicotine in maternal rats ...
Smith James F JF - - 2008
PURPOSE OF REVIEW: The assessment of fetal health has occupied our professional attention for many years. As the development of technologies for prenatal diagnostic techniques has progressed, applications of such technologies have aided in the overall assessment of fetal well-being. RECENT FINDINGS: Fetal heart-rate monitoring remains the main form of ...
Nørgaard J V - - 2008
Milk yield is reduced by pregnancy, and the present experiment was conducted to study the biological basis for the negative effect of pregnancy on milk yield. A total of 16 dairy cows were fed at either a normal or a low feeding level (eight cows per treatment), and half of ...
Teichert Russell W - - 2008
Although the neuromuscular nicotinic acetylcholine receptor (nAChR) is one of the most intensively studied ion channels in the nervous system, the differential roles of fetal and adult subtypes of the nAChR under normal and pathological conditions are still incompletely defined. Until recently, no pharmacological tools distinguished between fetal and adult ...
Chourasia Vijay S - - 2008
Over the past few years, various devices and techniques have been developed for electronic fetal monitoring (EFM), which is performed during pregnancy or continuously during labor to ensure normal delivery of a healthy baby. We reviewed and analyzed the performance of currently used EFM techniques with the goal of determining ...
Mao Caiping - - 2008
Prenatal exposure to nicotine can be associated with fetal abnormal development and brain damage. This study determined the effect of administration of nicotine with associated in utero hypoxia in maternal rats from early, middle, and late gestation on fetal blood hemoglobin, and expression of cholinergic receptor subtypes in the fetal ...
Amer-Wahlin I - - 2007
ST waveform analysis of fetal electrocardiogram (ECG) for intrapartum surveillance (STAN) is a newly introduced method for fetal surveillance. The purpose of this commentary is to assist in the proper use of fetal ECG in combination with cardiotocography (CTG) during labour. Guidelines and recommendations concerning CTG and ST waveform interpretation ...
Su Lin-Lin - - 2007
INTRODUCTION: Intrapartum fetal monitoring is essential for the identification of fetal hypoxia to reduce perinatal morbidity and mortality. Cardiotocography is associated with low specificity for fetal acidosis and poor perinatal outcome leading to unnecessary operative deliveries. ST waveform analysis of the fetal electrocardiogram has been shown to be a promising ...
Buczinski Sébastien M C - - 2007
Cloning technology is associated with multiple losses throughout pregnancy and in the neonatal period. Any maternal or fetal disease can compromise pregnancy. A paucity of data are available on bovine fetal well-being in late pregnancy; development of well-being assessment methods might augment early diagnosis of abnormal pregnancy or fetal distress, ...
Farrell Jody A - - 2007
It is important to recognize that it is only during our lifetime, the last decades of the 20th century, that the fetus has become a patient, with much of the credit due to the powerful imaging and sampling techniques now available. The secret life of the fetus has been revealed ...
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