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Higashi Yuko - - 2013
We present a 39-year-old pregnant woman with Behçet's disease who was treated successfully with granulocyte and monocyte adsorption apheresis (GMA). There were no complications or adverse effects during her pregnancy and delivery. The neonate manifested no abnormalities.
Elad David - - 2013
Maternal-to-fetal transfer of nutrient and other substances occurs across the placental barrier (PB) which is made up of endothelial cells (EC) on the fetal side and the syncytiotrophoblast (STB) on the maternal side. Numerous studies were conducted to explore the transport characteristics across the STB layer, which is also considered ...
Robertson Hugh - - 2013
We present a case of diffuse sphenoid bone cavernous hemangioma in a 22-year-old primigravid woman. Her disease first manifested clinically as progressively decreasing vision in her left eye during her third trimester of pregnancy. We also discuss the known causes and some theoretical causes of cavernous hemangioma enlargement during pregnancy.
Kazama Itsuro - - 2013
Background: Prostaglandin (PG)-specific organic anion transporter (OAT-PG) is a recently identified renal transporter involved in the local clearance of prostaglandin E2 (PGE2). Since the renal biosynthesis of PGE2 is not increased during pregnancy, this transporter expression would affect the gestational changes in the renal PGE2 content. Methods: Kidneys from rats ...
Freeman S L - - 2013
Persistence of free fluid in the uterine lumen of bitches with endometrial hyperplasia appears to be diagnostic for mating-induced endometritis and is associated with reduced chances of pregnancy. This study investigated the possibility that reduced fertility might be associated with an effect of uterine fluid on sperm. Uterine lavage fluid ...
Jones C J P - - 2013
Blood vessel glycosylation at the fetomaternal interface of four near-term specimens of tammar wallaby, Macropus eugenii, has been examined at days 23-26 of the 26.5 day pregnancy and compared with that of other species. A panel of 23 lectins was used to compare vasculature in tammar with non-mammalian (shark, skink) ...
Einarsdottir Helga - - 2013
The neonatal receptor (FcRn) extends the half-life of human immunoglobulin (Ig)G and transports it across the placenta, providing the newborn with humoral immunity. Of the four subclasses, IgG3 stands out with strong effector functions, short half-life (7 days vs. 21 days for other subclasses), and poor placental transport. We recently described ...
Pritchett-Corning Kathleen R - - 2013
Although rats in various stages of pregnancy are routinely shipped by vendors, the effects of shipping on pregnancy outcomes have not been reported. This study examined the effects of shipping rats 1 day after mating. Two outbred stocks, (Crl:CD(SD), Crl:WI(Han)) and one inbred strain (F344/Crl) of rats (n = 300/strain) ...
Ravangard Samadh F - - 2013
Placenta membranacea is a rare placental disorder characterized by the presence of fetal membranes (complete or partially) covered by chorionic villi. A 35-year-old woman, gravida 1, was admitted for preterm labor at 24 weeks and 5 days. She subsequently developed heavy vaginal bleeding and underwent a classical cesarean delivery for suspected abruption. ...
Simmons D G - - 2013
Sulfate is an important nutrient for fetal growth and development. The fetus has no mechanism for producing its own sulfate and is therefore totally reliant on sulfate from the maternal circulation via placental sulfate transport. To build a model of directional sulfate transport in the placenta, we investigated the relative ...
Andersen Stine Linding - - 2013
BACKGROUND: Placental transport of iodide is required for fetal thyroid hormone production. The sodium iodide symporter (NIS) mediates active iodide transport into the thyroid and the lactating mammary gland, and is also present in placenta. NIS is competitively inhibited by thiocyanate from maternal smoking, but compensatory autoregulation of iodide transport ...
Ahmadimoghaddam Davoud - - 2013
In our previous study, we described synchronized activity of organic cation transporter 3 (OCT3/SLC22A3) and multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter in the passage of organic cations across the rat placenta and the role of these transporters in fetal defense; in this study we hypothesized that changes in placental ...
Vinot C C EA 3620, Université Paris Descartes, Paris, - - 2013
Nowadays, antiretroviral therapy is recommended during pregnancy to prevent mother-to-child transmission of HIV. However, for many antiretroviral drugs, including maraviroc, a CCR5 antagonist, very little data exist regarding placental transfer. Besides, various factors may modulate this transfer, including efflux transporters belonging to the ATP-binding cassette (ABC) transporter superfamily. We investigated ...
Ideta Atsushi - - 2013
Cryopreservation methods using liquid nitrogen (LN(2)) for gametes and embryos are prevalent in mammalian artificial reproduction. However, the pregnancy rate from frozen embryos has not improved over the past two decades because freeze-thawing causes significant damage. The strict regulation of transportation of LN(2) containers by airlines also limits exchange between ...
Grinschgl Isabella - - 2012
Morphology in combination with flow cytometry is an inexpensive and fast tool to characterize important reasons for early gestational loss. Early partial hydatidiform moles are especially difficult to identify as not all have developed the typical histological features of central cistern formation and trophoblastic hyperplasia of the chorionic villi. Angiomatoid ...
Takeda Akihiro - - 2012
A 26-year-old primigravida patient was referred with suspicion of ectopic pregnancy 39 days after her last menstrual period. Her serum β-human chorionic gonadotropin value was 3812 mIU/mL. As we suspected the existence of ectopic pregnancy with bilateral dermoid cysts, laparoendoscopic single-site surgery was performed. After dissection of dense pelvic adhesion, ...
Neves R C - - 2012
The objective was to compare reproductive performance with management programs based on an automated activity monitoring (AAM) system or a synchronized breeding program under field conditions. In total, 1,429 Holstein cows from 3 commercial herds in Ontario, Canada, were enrolled over 1 yr in a randomized controlled trial. At each ...
Montouchet Calypso C School of Public Health, Imperial College London, W2 1NY, UK. - - 2013
Here we estimate the direct medical costs to the National Health Service (NHS) of unintended pregnancies in 2010 and identify populations at risk for unintended pregnancies. The number of unintended pregnancies in England in 2010 was estimated based on the number of induced and spontaneous abortions, live births and ectopic ...
Sholapurkar S L - - 2012
A recent opinion survey of British Obstetricians revealed 'early' fetal heart rate (FHR) decelerations as the commonest type in their practice. This contrasts with the guidelines by the National Institute for Health and Clinical Excellence, UK (NICE 2007) that 'true uniform early decelerations are rare and most decelerations are variable'. ...
Heller Debra S - - 2012
Context.-Chronic histiocytic intervillositis is an uncommon and poorly recognized lesion associated with poor perinatal outcomes, including intrauterine growth retardation and stillbirth. It has a high recurrence rate. Objective.-To evaluate utility of CD68 immunostaining in the evaluation of chronic histiocytic intervillositis. Design.-Institutional review board-approved retrospective review was performed. Cases were selected ...
Hill James B - - 2012
Evidence-based guidelines regarding intrapartum fetal surveillance from three countries (United States, Canada, and Australia/New Zealand) were reviewed. The similarities in the three national guidelines (purported etiology, management of periodic changes, and intermittent auscultation for low-risk women) are understandable. Differences in recommendations (role of fetal admission test, amnioinfusion for variable decelerations, ...
Donaldson J F - - 2012
OBJECTIVE: Surgery, ionising radiation and anaesthesia in the presence of an undetected pregnancy could be harmful. British guidelines state that female patients of 'childbearing age' should have their pregnancy status established before surgery. Approaching this topic with an adolescent girl can be challenging. DESIGN: The authors conducted an observational study ...
Yoon Jeong - - 2011
Since IVF program was first established, various types of media and culture systems have been developed either in-house or commercially. The aim of this study was to compare the efficacy of in-house Maria Research Center (MRC) media to that of commercially available Sydney IVF media in human day 3 embryo ...
Serva Waldmiro Antônio Diégues - - 2011
To describe the course of migraine without aura and migraine with aura during pregnancy and factors that could influence its course, among migraine sufferers before pregnancy. A cross sectional study undertaken at the IMIP, Brazil. Out of 686 consecutively assisted women, at the first postnatal week, 266 were identified as ...
Shaw Julie L V - - 2012
As part of successful human reproduction, the Fallopian tube must provide a suitable environment for pre-implantation development of the embryo and for efficient transport of the embryo to the uterus for implantation. These functions are coordinated by paracrine interactions between tubal epithelial, smooth muscle and immune cells and the cells ...
Waclawik Agnieszka - - 2011
Ovarian progesterone induces essential changes leading to a temporary state of uterine receptivity for conceptus implantation. Estrogens secreted by the porcine conceptus on day 11 and 12 of pregnancy, provide the initial signal for maternal recognition of pregnancy and maintenance of a functional corpus luteum (CL) for continued production of ...
Keenan Jeffrey A - - 2011
Ulipristal acetate is the first selective progesterone receptor modulator approved for postcoital contraception in the US. It appears to be significantly more effective in inhibition of ovulation than other forms of emergency contraception. However, ulipristal acetate is structurally similar to mifepristone, and several lines of evidence suggest that a postfertilization ...
Shin David S - - 2011
The objective of this article is to describe the CT and MRI findings of early intrauterine pregnancy. Early pregnancy should be considered when CT or MRI shows a fluid-filled cystlike structure in the uterus of a woman of reproductive age especially if there is a coexistent ovarian corpus luteum cyst.
Le A - - 2011
This work aimed to study the features of primary fallopian tube carcinoma during pregnancy and to improve the understanding of clinical gynecologists. The clinical features of a case of primary fallopian tube carcinoma during pregnancy were analyzed. The final diagnosis was Stage IA fallopian tube cancer after cesarean delivery. It ...
Valenzano Menada Mario - - 2010
We describe a rare case of transplacental-transmitted maternal melanoma to the placenta and foetus during the second pregnancy of a 28-year-old woman. She was aware of a greyish-brown nodular lesion on the right gluteus during her first pregnancy. On histological examination, this lesion resulted to be an amelanocitic melanoma. Breast ...
Lejeune B - - 2011
A 2-year-old Red Holstein cow was presented with uterine torsion at 235 days of pregnancy. The fetus extracted by cesarean section had weak vital signs and marked abdominal distention. An edematous pouch that contained tubular structures with peristaltic activity was associated with the umbilical cord. Because of poor prognosis, both ...
Nelson David B - - 2010
BACKGROUND: Neurofibromatosis is a rare pregnancy complication that can present with rapidly enlarging masses that have malignant potential. CASE: A 19-year-old primagravid woman with a known history of neurofibromatosis presented in her first trimester with pulmonary complaints. A malignant mediastinal mass was diagnosed and resected, with additional treatment options declined. ...
Rac Martha W F - - 2010
BACKGROUND: The Jarisch-Herxheimer reaction is an acute systemic event that can occur during the treatment of spirochetal infections. During pregnancy, it can cause signs and symptoms in both the mother and fetus, including fever, tachycardia, uterine contractions, and fetal heart rate pattern changes. CASE: A pregnant woman with limited prenatal ...
Cleuziou Julie - - 2010
Pregnancy in women with biological heart valve prosthesis might lead to a faster degeneration of the prosthesis. We analyzed the rate of prosthesis replacement and the outcome of pregnancies in women with biological valve prosthesis. Between 1976 and 2006, 100 female patients aged 18-40years at time of the study, underwent ...
Gupta Amie - - 2010
The issue of whether hormones influence malignant melanoma (MM) has been controversial for many years. Although early case reports demonstrated a negative effect of hormones, recent evidence has not supported a potential role for hormones in MM. We address whether exogenous and endogenous hormones influence a woman's risk for MM ...
Brady Mary S - - 2010
Objective: There exists a strong belief among physicians and the lay public that pregnancy adversely affects survival in patients with melanoma. The authors asked if there was any evidence to support this in patients with clinically localized disease. Methods: The authors reviewed the published literature on MEDLINE. Results: The authors ...
Osime O C - - 2010
Intussusception in pregnancy is rare and making a preoperative diagnosis is extremely difficult. The objective of this paper is to report a case of intussusception in a pregnant woman and to review the literature on the subject with a view to highlighting the peculiarities of this condition. The case file ...
Paradela Sabela - - 2010
Melanoma is an uncommon tumour in childhood. Only isolated cases in pregnant patients younger than 18 years old have been previously described, therefore the biological behaviour of cutaneous melanoma in this group of age remains largely unknown. We report a single-institution experience with three patients who developed cutaneous melanoma before ...
Chan May P - - 2010
BACKGROUND: Changes in the clinical appearance of benign dermal nevi during pregnancy may be concerning for malignant transformation. Because the hormonal milieu of pregnancy has not proven to alter their banal behavior, histologic characterization is needed to prevent over-diagnosis and unnecessary treatment. METHODS: Dermal nevi excised from pregnant women (n ...
Ferrarini Alessandra - - 2009
We report on two familial cases from a non-consanguineous marriage, presenting multiple intestinal and choanal atresia. Massive hydramnios and dilatation of the bowel were observed at 29 weeks of gestation during routine ultrasound scan of a healthy mother. The fetal karyotype was normal and cystic fibrosis screening was negative. Regular ...
Hameed Afshan B - - 2009
Mitral stenosis is one of the more commonly seen valve lesions encountered in pregnancy. The pathophysiologic implications, management strategies, and a comprehensive review of literature over the past 20 years for optimal timing of catheter balloon commissurotomy during pregnancy are discussed. Mechanical relief of obstruction is indicated for cases of ...
Lomotey Chaylah J - - 2009
OBJECTIVES: A study was conducted to assess the prevalence of maternal syphilis and estimate the rate of congenital syphilis in five rural villages surrounding Jeremie, Haiti. METHODS: This research was a retrospective observational study. Data were extracted from the Haitian Health Foundation's public health database and verified through original clinical ...
Miller Ehud - - 2010
Malignant melanoma (MM) was considered a hormone-sensitive tumour, and pregnancy was thought to increase its risk and cause faster progression and earlier metastasis. Several controlled studies demonstrated similar survival rates between pregnant and non-pregnant patients and concluded that early reports of advanced MM of pregnancy were probably due to late ...
Boccuzzi Giacomo - - 2009
A 26-year-old woman was admitted to our hospital because of exertional dyspnea (New York Heart Association III), general fatigue and palpitations over the past 2 months. She had normal psychosomatic development until adulthood, no previous pregnancies and a history of rheumatic fever at young age. Although she referred a slow ...
Nading Mary Alice MA Division of Dermatology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, - - 2009
Large congenital nevi carry a slightly increased risk of melanoma. Pregnancy poses an additional challenge in the monitoring of these patients because little is known regarding the effects of increased estrogen levels on congenital nevi. A young woman was observed to have clinical lightening of her garment nevus and satellite ...
Pag?s C - - 2010
BACKGROUND: Although metastatic melanoma occurrence during pregnancy challenges the physician in several ways, only a few studies have been published. OBJECTIVES: Our aim was to investigate therapeutic management together with maternal and fetal outcomes in pregnant women with advanced melanoma. METHODS: A French national retrospective study was conducted in 34 ...
Wolff Tracy - - 2009
BACKGROUND: In 2004, the U.S. Preventive Services Task Force strongly recommended that clinicians screen all pregnant women for syphilis infection. PURPOSE: To update the evidence on screening pregnant women for syphilis infection. DATA SOURCES: MEDLINE searches from 1 January 2003 through 31 July 2008, recent systematic reviews, reference lists of ...
Driscoll Marcia S - - 2009
Multiple difficult questions arise when a pregnant woman presents to the dermatologist with a changing melanocytic nevus or melanoma. Our review of the literature provides some insight into these issues. We recommend that a changing pigmented lesion in the pregnant woman should be biopsied promptly and can be safely performed. ...
Ali Unzila - - 2009
For women requiring valve replacement surgery, it is unclear which type of valve offers the greatest chance of a healthy pregnancy. This case describes a successful pregnancy outcome following the Ross procedure, which involves replacing the aortic valve with an autologous pulmonary valve. Due to left ventricular outflow tract obstruction, ...
Korkmaz Askin A - - 2008
Mechanical heart valve thrombosis during pregnancy is a challenging condition. We present a pregnant patient with stuck mechanical mitral valve. During the 36th week of pregnancy, she was admitted to our emergency clinic because of aggravated dyspnea, tachypnea, and cyanosis. Echocardiography revealed stuck mechanical valve in mitral position and she ...
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