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Onderoglu L - - 1995
Although rheumatic diseases are reported to be almost eradicated in the developed countries, they still continue to contribute significantly to maternal mortality in the developing world. Surgical therapies need to be considered for those patients who do not respond satisfactorily to medication. However, valve replacement or valvulotomy during pregnancy carries ...
Coles F B - - 1995
Descriptive characteristics and clinical information from 322 cases of congenital syphilis were reviewed. The births (318 mothers) included 31 (10%) stillborn and 59 (18%) with clinical evidence of congenital syphilis. Only 60 (19%) had a complete laboratory workup, including radiographs of long bones and spinal fluid analysis. For a subset ...
Diaferia A - - 1995
Primary melanoma is the most malignant and the least frequent of all cutaneous tumors. Its incidence in pregnancy varies from 0.1 to 2.8/1000. Up to today, impact of pregnancy on melanoma's course is still a much debated question in the literature. Some earlier reports suggested a particularly serious prognosis for ...
Wenisch C - - 1994
A 59-year-old man with the diagnosis of endocarditis of the mitral valve due to Streptococcus mitis was treated with penicillin G, gentamicin, and later with clindamycin as inpatient for 3 weeks. Thereafter outpatient therapy with parenteral teicoplanin 3 x per week was initiated. After 17 days of teicoplanin treatment he ...
Goens J L - - 1994
The incidence of syphilis is increasing, predominantly among urban heterosexuals. Early recognition is important in preventing progression of the disease and transmission of Treponema pallidum to the fetus. Untreated primary syphilis is characterized by intervals of active disease punctuated by periods of latency. Not all patients progress through each phase, ...
ElTabbakh G H - - 1994
The incidence of congenital syphilis is on the rise. Penicillin continues to be the drug of choice for it during pregnancy. A penicillin-allergic woman with primary stage syphilis who was treated initially with erythromycin presented with fever and nonimmune fetal hydrops secondary to an intrauterine syphilitic infection. Following desensitization and ...
Young S A - - 1994
Five cases of macerated stillborn fetuses with congenital syphilis were studied. Despite severe maceration with visceral autolysis, spirochetes could be easily detected using Warthin-Starry stains. Clues that led to performing silver stains included the presence of an enlarged liver, spleen, chorioamnionitis, and nucleated red blood cells in villous capillaries. In ...
Khwa-Otsyula B O - - 1994
Two patients who had mitral valve replacement presented during the second trimester of pregnancy. Both had uneventful pregnancies ending in normal delivery of healthy female babies. Though patients who are haemodynamically stable tolerate pregnancy well, because of the substantial risks of anticoagulant therapy, it is prudent to advise against pregnancy ...
Rutgers S - - 1993
A medical audit was performed in Umzingwane District, Zimbabwe, to assess the quality of antenatal care in 1991 regarding detection and management of syphilis. Two thousand one hundred and sixty one women booked for antenatal care, 1433 (66 pc) received a RPR test result, 197 (14 pc) tests were positive. ...
Banning A P - - 1993
The outcome of unrelieved severe symptomatic aortic stenosis in pregnancy is poor. Though the valve lesion can be corrected surgically before delivery at a low risk to the mother, cardiopulmonary bypass during pregnancy carries a high risk to the fetus. Two patients in the second trimester of pregnancy were successfully ...
Driscoll M S - - 1993
The effect of pregnancy on the clinical course of malignant melanoma (MM) is unclear. Early clinical and laboratory evidence suggested a relation between hormones and MM and subsequently between pregnancy and MM. We reviewed the literature on MM and pregnancy to address three questions: What is the effect on prognosis ...
Kajdacsy-Balla A - - 1993
Female LSH hamsters infected with Treponema pallidum subsp, endemicum before pregnancy or during early pregnancy transmit a form of syphilis to the fetus that is similar to human congenital syphilis. The offspring develops rhinitis, skin rash, failure to thrive, and hepatosplenomegaly. T. pallidum is detectable in their livers, spleens, and ...
Ilagan N B - - 1993
Increasing rates of congenital syphilis have been reported in recent years despite the availability of adequate therapy. In our perinatal-neonatal center, approximately 1.5% of newborns have reactive serologic tests for syphilis. Untreated or partly treated maternal syphilis can adversely affect neonatal outcome since the treponeme can cross the placenta at ...
Garavoglia M - - 1993
The myoelectric activity of 25-30 cm ileal loops interposed isoperistaltically or antiperistaltically between colon and rectum was investigated 1-3 and 20-22 weeks after surgery, in growing pigs chronically fitted with intraparietal electrodes on the loop and the ileum. The fundamental motor profile of the small intestine consisting of migrating myoelectric ...
Trahair J F - - 1993
Experimental obstruction of the fetal small intestine resulted in massive hypertrophy of the segment proximal to the site of obstruction. Villus morphology was grossly abnormal. Enterocytes developed many irregular features, most notably cytoplasmic extensions (pseudopods, or blebs) from their apical surface. Distal to the site of obstruction, morphological anomalies which ...
Kim Y K - - 1992
Acquired tufted angioma is a distinctive condition that is different from other types of acquired vascular proliferation. Despite the progressive spread of these angiomas, they appear to be benign, and malignant change has not been encountered. We describe a case of recurrent acquired tufted angioma associated with pregnancy, an association ...
Piper J M - - 1992
The dismal prognosis of dilated cardiomyopathy and its resulting tachyarrhythmias has recently been improved by technical advances such as the automatic implantable cardioverter defibrillator. We report a successful pregnancy in a patient with chronic cardiomyopathy and malignant tachyarrhythmias necessitating use of this device, with a documented defibrillator discharge and monitored ...
Björk V O - - 1992
Two 5-year observations of goats with microporous surfaced Björk-Shiley Monostrut mitral heart valves without anticoagulation show the important point that one went through four the other two normal pregnancies with delivery of fourteen kids. Furthermore, the local findings on the valves suggest that the porous surface should be used only ...
Kuppens E - - 1992
A 35-year old woman developed six primary cutaneous melanomas during her third pregnancy. She had received clomiphene treatment for nearly 2 years previously. She developed two more primary melanomas 15 and 21 months after giving birth. All melanomas were histologically associated with preexisting dysplastic naevi. The patient showed the characteristic ...
Stephen S J - - 1992
The findings in rheumatic mitral stenosis appear to have undergone changes, probably in association with improved socioeconomic conditions, in developing countries. The objective of this study was to assess such changes and to adapt strategies of management. The clinical and pathologic features, mortality rate, long-term functional class and restenosis rate ...
Oikawa M - - 1992
To elucidate the pathomorphogenesis of extremely shortened small-intestinal villi, occurring spontaneously in neonatal foals, the morphology of the small intestine with stunted villi was studied in eight cases. All intestinal wall elements and the villi were poorly developed. Most villi were found to be extremely short throughout the entire length ...
Chow W H - - 1992
Percutaneous balloon mitral valvotomy (PBMV) using the Inoue balloon catheter was performed successfully in 2 patients with severe mitral stenosis refractory to medical treatment during pregnancy. Because of its unique design and ease of manipulation, we recommend the Inoue balloon catheter for performing PBMV in selected patients with mitral stenosis ...
Slingluff C L CL - - 1992
Among 100 patients diagnosed with melanoma during pregnancy and followed a mean of 6.8 years, when compared with a nonpregnant female population, there was a significantly shorter disease-free interval for the pregnant group. Median disease-free intervals were 5.8 and 11.9 years, respectively. The time to development of lymph node metastases ...
Braverman A C - - 1991
A previously healthy young woman who developed the new onset of symptomatic sustained ventricular tachycardia during pregnancy is described. Evaluation revealed mitral valve prolapse with minimal mitral regurgitation, and normal left ventricular size and function. The arrhythmia resolved after delivery, but recurred nine months later in a nonsustained form. Electrophysiologic ...
Shields C L - - 1991
A review of 3706 consecutive patients with uveal melanoma over a 17-year period revealed that 16 patients (0.4%) were pregnant women at the time of diagnosis. The mean age at presentation in this group was 30 years and the mean months of gestation at the time of diagnosis of the ...
Esteves C A - - 1991
During pregnancy, medically refractory congestive heart failure due to mitral stenosis continues to present a clinical challenge and optimal management remains controversial. Thirteen women underwent balloon mitral valvotomy for control of functional class III or IV congestive heart failure due to mitral stenosis during pregnancy. The mean gestational age at ...
McBride A - - 1991
The clinical features of 100 dysplastic nevi were tabulated. Although certain characteristics were present in most or all of these melanocytic nevi, there was a marked heterogeneity of other clinical features. The preponderant type of large (greater than or equal to 8 mm) melanocytic nevus in patients with classic dysplastic ...
Frecentese D F - - 1991
In the United States, the incidence of acquired syphilis has increased thirty four percent in the last decade with young, black, urban dwelling, drug dependent females representing the highest risk group. Concomitantly, congenital syphilis has increased causing spontaneous abortions, stillbirths, and neonatal morbidity and longterm neurologic sequela. Because physicians are ...
McIvor R A - - 1991
Severe aortic stenosis may potentiate sudden life threatening complications during pregnancy. We report a case of successful percutaneous balloon aortic valvuloplasty in a pregnant patient with severe symptomatic aortic stenosis due to congenital bicuspid aortic valve at 14 weeks' gestation. Use of percutaneous valvuloplasty allowed asymptomatic progression of the pregnancy ...
Damiba A E - - 1991
Recent trends in reported primary genital syphilis and genital ulcer disease (GUD) were assessed in Burkina Faso using incidence data reported to the Ministry of Health. From 1978 to 1983 the yearly reports of genital syphilis and GUD rose by 42%. A single period moving average was calculated for each ...
Rawstron S A - - 1991
A pregnant women with secondary syphilis received appropriate therapy with penicillin in the last trimester of pregnancy. At delivery, her titre had fallen fourfold, and the baby had a non-reactive cord blood titre at birth. However, the treatment failed to prevent infection in the infant, and the baby had developed ...
MacKie R M - - 1991
To determine the effect of pregnancy on prognosis in melanoma we investigated 388 women treated for stage 1 primary cutaneous disease during their childbearing years. 85 women had been treated before any pregnancy, 92 during pregnancy, 143 after they had completed all pregnancies, and 68 between pregnancies. Women who had ...
Colloby P S - - 1991
We have assessed the degree of observer variation of both Breslow depth and Clark's level in a series of 50 thin malignant melanomas. Our findings are similar to those of previous international studies in the Breslow depth is the more reproducible measure. Significant intra- and inter-observer variation exists and in ...
Huang C C - - 1991
A 31-year-old woman who presented with a thymoma and myasthenia gravis during pregnancy is reported. The thymoma showed an increase in size during the next 1.5 months. The pregnancy was terminated and a total thymothymectomy was performed with beneficial results. Pathology revealed a lymphoepithelial type with capsule invasion. Thymoma occurring ...
Chen C R - - 1990
The first 71 patients with rheumatic mitral stenosis who successfully underwent single rubber-nylon balloon (Inoue balloon) percutaneous mitral valvuloplasty (PMV) from November 1985 to August 1988 had a mean follow-up period of 27.1 +/- 11.6 months (range, 14 to 48 months). Functional status before PMV was New York Heart Association ...
Harkin K P - - 1990
A 29 year old expectant mother was critically ill at 27 weeks gestation with disseminated metastatic malignant melanoma and was treated with dacarbazine. A dramatic remission was induced and at 38 weeks gestation she went into labour spontaneously and delivered a healthy infant. She relapsed and died eight weeks post ...
Deshpande A D - - 1990
A case of recurrent Bell's palsy occurring in two successive pregnancies in a 37-year-old woman is presented. The causes of facial nerve paralysis of the lower motor neurone type are discussed. The rate of recurrence of Bell's palsy during pregnancy is unknown. Treatment with corticosteroids of Bell's palsy during pregnancy ...
Hira S K - - 1990
Despite availability of simpler serologic tests for syphilis and near cure with penicillin, unacceptably high prevalence of infectious maternal syphilis exist in many developing countries, including Zambia. It is the foremost risk factor for mid-trimester abortions, stillbirths, prematurity and morbidity and mortality among infants born with congenital syphilis in Zambia. ...
Abid A - - 1990
Between 1977 and 1987, seven pregnant women (mean age 28 years) had closed mitral valvotomy through a left lateral thoracotomy during their first (3 cases), second (2 cases) or third (2 cases) trimester. Surgery was necessary either because of acute heart failure with pulmonary edema not responding to medical treatment ...
Klein V R - - 1990
Thirty-three gravidas with syphilis were monitored with hourly vital signs and examinations for 24 hours after treatment with benzathine penicillin G. Fifteen (45%) of the subjects had a Jarisch-Herxheimer reaction, including all three, 12 of 20 (60%), and none of ten of those with primary, secondary, and latent syphilis, respectively. ...
Char D H - - 1990
We retrospectively reviewed ultrasonographic data on 32 uveal melanomas that had been studied both at a referral institution and at our centre within a six-week period. Generally there were good correlations between ultrasonographic measurements of tumour thickness. The mean absolute difference in ultrasound measurements of tumour thickness was 0.64 mm ...
Duthie S J - - 1990
Between 1984 and 1988 inclusive 34 patients with syphilis during pregnancy were identified in this unit by routine serological screening. There were 2 stillbirths in this group of patients giving a perinatal mortality rate of 59 per 1,000 total births. Analysis of the patients' history and physical examination findings did ...
McManamny D S - - 1989
Treatment of the pregnant woman with melanoma is contentious. With the aid of a computerized melanoma register, in which pregnancy data can be recorded, 290 women with melanoma were reviewed (249 alive and 41 dead). Overall, 23 patients were pregnant at the time of diagnosis of melanoma, and another 23 ...
Bowell P - - 1989
Between 1983 and 1987, 62 out of 76519 pregnancies in 51 mothers had a positive miniaturised Treponema pallidum haemagglutination assay (TPHA) test--1 in 1234, or 0.81 per 1000 births. About two thirds of these mothers had syphilis and the remainder non-venereal treponematoses such as yaws or pinta. Antenatal screening identified ...
Wyshak G - - 1989
A higher risk of reproductive system disorders, (which include benign tumors, endometriosis, dilation and curettage, hysterectomy, and other disorders requiring gynecologic biopsies) exist among women with cutaneous melanoma as compared to women with skin cancers: The odds ratio (OR) is 3.2, 95% confidence limits (1.0, 10.1), p = 0.049; as ...
Wong J H - - 1989
The clinical course of 66 patients with stage I melanoma, diagnosed during pregnancy, treated in the Division of Surgical Oncology at UCLA, was retrospectively reviewed. These patients were compared with 619 nonpregnant female patients with melanoma. There was no significant difference between the pregnant population and control population with respect ...
Walsted A - - 1989
A patient is described with two primary malignant melanomas which developed during consecutive pregnancies four years apart. The first melanoma was of the cutaneous nodular type located on the arm. The second, of the superficial spreading type, was located in the oral mucosa near the right tonsil. The influence of ...
Ichihashi M - - 1989
An experimental study of the relative biological effectiveness (RBE) of thermal neutron capture therapy (TNCT) for melanoma cell inactivation using 10B1-paraboronophenylalanine (10B1-BPA) was carried out to demonstrate a high therapeutic effect of TNCT, compared with that of fast neutron. Cells preincubated with or without 10B1-BPA at a concentration of 50 ...
Phaosavasdi S - - 1989
The intramuscular injection of benzathine penicillin G 2.4 million units weekly for 3 consecutive weeks to syphilitic pregnant women was again confirmed to be clinically effective for prevention of their neonates from congenital syphilis and well accepted as treatment for syphilis in pregnancy. It was administered to 184 cases, or ...
Parker C R CR - - 1988
Several pregnancy complications that are thought to cause chronic intrauterine stress have been found to lead to inappropriate fetal development and reductions in estrogen production. In the current study we sought to evaluate the fetoplacental unit in pregnancies complicated by maternal syphilis (n = 37), with and without fetal infection. ...
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