Search Results
Results 151 - 200 of 269
1 2 3 4 5 6 >
Parashuraman Seetharaman - - 2005
We investigated the mechanism by which Salmonella inhibits transport to lysosomes to survive in macrophages. We have purified the Salmonella-containing phagosomes from macrophages and determined the presence of different endocytic Rab proteins on the phagosomes. Our results have shown that live Salmonella-containing phagosomes recruit more Rab5 than dead Salmonella-containing phagosomes. ...
Castellá M - - 2004
BACKGROUND AND OBJECTIVES: A series of women with pregnancy-associated thrombotic thrombocytopenic purpura, is presented. This study will focus on the relationship between thrombotic thrombocytopenic purpura and pregnancy and on maternal and neonatal outcomes. MATERIALS AND METHODS: Among forty-six consecutive patients with thrombotic thrombocytopenic purpura, nine pregnant patients were identified. RESULTS: ...
Parton Robert G - - 2004
The endocytic trafficking of caveolae has been the subject of some controversy for many years. A new study (Pelkmans et al.) shows that budded caveolae can interact with both the caveosome and the early endosome and that caveolin-enriched regions of the early endosomal membrane form unusually stable domains that can ...
Schäfers Michael - - 2004
A myocardial remodeling in dilated cardiomyopathy (DCM) after partial left ventriculectomy (PLV) has been previously discussed. The aim of this study was to investigate the functional changes in the follow-up of patients with DCM undergoing PLV using electrocardiographically triggered perfusion SPECT (gated SPECT). METHODS: Twelve DCM patients (10 men, 2 ...
Sundram F - - 2004
Thrombotic thrombocytopenic purpura (TTP) is a rare condition but associated with 90% mortality if left untreated. The diagnosis is usually made when there is thrombocytopenia and microangiopathic haemolytic anaemia, although the full pentad also includes fever, renal impairment, and neurological dysfunction. A variety of underlying causes have been implicated in ...
Vesely Sara K - - 2004
BACKGROUND: Recurrent thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) during a subsequent pregnancy is an important concern because pregnancy may increase the risk for relapse. STUDY DESIGN AND METHODS: Outcomes of all pregnancies after recovery from TTP-HUS in the Oklahoma TTP-HUS Registry, a cohort of 301 consecutive patients during the period ...
McLeary J B - - 2004
Inhibition in Reversible Addition-Fragmentation chain Transfer (RAFT)-mediated polymerisations is currently a controversial issue; here we provide evidence that the slow "propagation" of the initiating and leaving group radicals during the early part (the period of consumption of the initial RAFT agent) of methyl acrylate RAFT-mediated polymerisation has characteristics similar to ...
Smets Koenraad - - 2004
A case of Möbius sequence after exposure to ergotamine during early development is reported. Vascular disruption is one of the theories explaining the pathogenesis of Möbius sequence. Ergotamine can cause vasospasm and a prolonged and marked increase in uterine tone. This is the second report suggesting a relation between maternal ...
Mayr Gerald - - 2004
We report on the oldest European songbird (Passeriformes), from the early Oligocene (30-34 million years ago) of Frauenweiler in Germany. The specimen represents the earliest associated remains of an early Tertiary passerine described so far. It ties the first appearance of Passeriformes in Europe to a minimum age of 30 ...
Koizumi Minako - - 2004
The clinical features of Schönlein-Henoch Purpura (SHP) consist of non-thrombocytopenic purpura in association with joint, gastrointestinal and renal involvements. Because it is uncommon in adults, there is little information on the effects of SHP on pregnancy in the literature. This report documents the clinical findings and outcome of an uncommon ...
Ducloy-Bouthors Anne-Sophie - - 2003
BACKGROUND: Thrombotic thrombocytopenic purpura (TTP) is a rare cause of severe thrombocytopenia in pregnancy. METHODS: Six pregnancies in five patients with TTP were followed prospectively over 5 years. Ultralarge von Willebrand factor (ULvWF) multimers and cleaving protease (cp) levels were measured. RESULTS: TTP relapsed, complicating four of the six pregnancies. ...
- - 2003
Some Fellows of the American College of Obstetricians and Gynecologists limit the scope of their practices solely to gynecology. The College considers early pregnancy complications (often up to 12-14 weeks of gestation) to be within the definition of gynecology. Liability insurance should cover the role of gynecologists in the management ...
Sivojelezova Anna - - 2003
One of my patients presented with bacteriuria early in her pregnancy. Urine culture was positive for Escherichia coli. I would like to prescribe a trimethoprim-sulfamethoxazole combination because it worked well for her in the past. What is known about the safety of this medication during early pregnancy? Evidence-based studies report ...
Ratnasooriya W D - - 2003
The root extract of Salacia reticulata Wight (family: Celastraceae) is used in Sri Lanka by traditional practitioners as a herbal therapy for glycemic control even during pregnancy. It is recognized that some clinically used antidiabetic drugs have harmful effects on pregnancy but the effects of the S. reticulata root extract ...
Lazarus Alan H - - 2003
Infusion of large amounts of intravenous immunoglobulin (IVIG) or polyclonal anti-D can reverse thrombocytopenia in patients with idiopathic thrombocytopenic purpura within hours of the administration of these products. It has been suggested that the effects of IVIG appear to far outlast several half-lives of the product. Several mechanisms have been ...
Draper Jan - - 2003
This paper presents a theoretical analysis of men's experiences of pregnancy, birth and early fatherhood. It does so using a framework of ritual transition theory and argues that despite its earlier structural-functionalist roots, transition theory remains a valuable framework, illuminating contemporary transitions across the life course. The paper discusses the ...
Sommers Christopher H - - 2002
Ionizing radiation can be used to pasteurize ready-to-eat (RTE) meat products. Thermal processing of RTE meats that contain dextrose results in the production of antioxidants that may interfere with ionizing radiation pasteurization of RTE meat products. Beef bologna was manufactured with dextrose concentrations of 0, 2, 4, 6, and 8%. ...
Isbister G K - - 2002
BACKGROUND: Spider bite is a subject of much medical mythology with prevalent fears that spiders cause severe envenoming, with neurotoxic effects or necrotic ulcers. Clinical experience and small studies suggest otherwise, but this has not been confirmed by prospective studies of bites by identified spiders. AIM: To describe the clinical ...
Porat Naomi - - 2002
This paper reviews the numerical dates available for the late Lower Paleolithic and early Middle Paleolithic in the Levant. We also present here new electron spin resonance dates for the late Lower Paleolithic sites of Holon, Yabrud I and Oumm Qatafa. Irrespective of dating techniques used, the ages of these ...
Paulsen E - - 2002
The Compositae plant feverfew (Tanacetum parthenium) is an important sensitizer in Europe and has been suspected of causing airborne Compositae dermatitis. A previous investigation of substances emitted from feverfew plants detected no sesquiterpene lactones, however, but mainly monoterpenes. The aims of this study were to test whether feverfew-allergic patients were ...
Ackermann Rebecca Rogers - - 2002
Recent evaluation of Neanderthal and modern human ontogeny suggests that taxon-specific features arose very early in development in both lineages, with early, possibly prenatal, morphological divergence followed by parallel postnatal developmental patterns. Here we use morphometric techniques to compare hominoid facial growth patterns, and show that this developmental phenomenon is, ...
Mozdziak Paul E - - 2002
The effect of early posthatch starvation on myonuclear apoptosis was examined in chickens. Male broiler chickens were or were not provided feed for the first 3-d posthatch. Subsequently, all chickens were provided feed for an additional 4-d posthatch. Chickens were killed at 3- and 7-d posthatch, and the pectoralis thoracicus ...
Proia A - - 2002
Thrombotic thrombocytopenic purpura (TTP) is a severe disorder affecting the microcirculation of multiple organ systems. Plasma therapy has significantly reduced the mortality rate. Infections, pregnancy, cancers, drugs, and surgery were frequently associated with the initial episodes and relapses. Women who are either pregnant or in the postpartum period make up ...
Rageh Mona A E - - 2002
Immunocytochemistry utilizing a monoclonal antibody (BV1; blood vessel 1) highly reactive to the vasculature of the adult newt showed that a developing vasculature was present during early, pre-blastema, and early-bud blastema stages of forelimb regeneration in this species. Infusion of Prussian Blue and DiI into the brachial artery further delineated ...
Ravenscroft J - - 2001
Photochemotherapy with psoralens and UVA (PUVA) is widely used in the treatment of psoriasis and many other skin conditions. Cutaneous adverse reactions to 8-methoxypsoralen (8-MOP) appear to be rare and may be difficult to distinguish from phototoxicity or UV-induced polymorphic light eruption. We describe a patient who had a systemic ...
Schou M - - 2001
The paper reviews briefly and comments in detail on selected events in the history of lithium treatment. The events include Cade's discovery of lithium's antimanic action, the discovery and establishment of its prophylactic action, the ensuing debate, amelioration and prevention of side effects and risks, use during pregnancy, non-compliance, selection ...
Elliott M A MA Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA. - - 2001
Thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS) are multisystemic disorders that are characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ischemic manifestations, resulting from platelet agglutination in the arterial microvasculature. Until the introduction of plasma-based therapy, TTP was associated with a mortality rate greater than 90%. Current outcomes of ...
Sendag F - - 2001
Splenectomy as a treatment for severe immunological thrombocytopenic purpura is rarely performed in the third trimester of pregnancy. We report a 28-year-old patient who presented at the 34th gestational week with severe immunological thrombocytopenic purpura resistant to both corticosteroid and intravenous immunoglobulin therapies. Splenectomy combined with delivery by cesarean section ...
Banon E - - 2001
Transcripts of early sessions for 7 personality-disordered male subjects participating in an ongoing naturalistic long-term dynamic psychotherapy project were rated for therapist interventions and alliance. Early transference interpretations were followed by increased defensiveness even when there was a solid alliance. Omitting transference interpretations in the face of an early negative ...
Kaseda S - - 2001
BACKGROUND AND OBJECTIVE: We have widely used a Ho:YAG laser to treat bullae thoracoscopically. STUDY DESIGN/MATERIALS AND METHODS: Bullae with broad necks were treated with a Ho:YAG laser thoracoscopically. Because one patient relapsed after application of fibrin glue in the early period, a DEXON (polyglycolic acid) mesh patch soaked in ...
Rosati P - - 2000
OBJECTIVE: To evaluate the acceptability of early transvaginal sonography by pregnant patients. METHODS: A questionnaire was completed by 246 patients and the resulting data were analysed. RESULTS: The incidence of discomfort was higher for the transabdominal than for the transvaginal route. Moreover, the transvaginal approach in early pregnancy, when compared ...
Churchill S E - - 2000
Implicit in much of the discussion of the cultural and population biological dynamics of modern human origins in Europe is the assumption that the Aurignacian, from its very start, was made by fully modern humans. The veracity of this assumption has been challenged in recent years by the association of ...
Margheritini F - - 2000
We present the outcome of a mould arthroplasty implanted for a congenital hip dysplasia in 1955 to revise a previous cup arthroplasty. This type of prosthesis, which has been developed on the basis of the concept of Smith-Peterson, by Prof. Marino-Zuco in Rome in the early 1940s, showed excellent results ...
Benton M J - - 1999
Recent claims from molecular evidence that modern orders of birds and mammals arose in the Early Cretaceous, over 100 million years (Myr) ago, are contrary to palaeontological evidence. The oldest fossils generally fall in the time range from 70-50 Myr ago, with no earlier finds. If the molecular results are ...
Fox R - - 1999
Recent improvements in the investigation of bleeding and pain in early pregnancy has led to simplified clinical guidelines. These in turn have created the opportunity for nurse-led early pregnancy assessment. We arranged for a gynaecology nurse-practitioner with experience to undergo additional training in early pregnancy care. She then took over ...
Blades B S - - 1999
During the past decade the chronology and hominin attributions of the Aurignacian have been revised or called into question. These controversies have coincided with an increased appreciation for the social complexity of Aurignacian culture in the realms of organic technologies and mobiliary and parietal manifestations of symbolic behavior. Lithic raw ...
Scott D B - - 1999
We have identified a new locus that regulates vegetative phase change and flowering time in Arabidopsis. An early-flowering mutant, eaf1 (early flowering 1) was isolated and characterized. eaf1 plants flowered earlier than the wild type under either short-day or long-day conditions, and showed a reduction in the juvenile and adult ...
Shiva Kumar V - - 1999
Vulval varicosities reportedly occurs in pregnant women. We report a case of vulval varicosities with associated varicosities of the breast and saphenous veins, which regressed completely post partum with conservative management.
Kostova E K - - 1999
Chronobiology and biometeorology have developed since ancient times of world history (China, Greece, etc.). Different authors have studied the origin and early development of medicine and related sciences in Bulgaria (Apostolov et al 1982, Georgiev 1987, etc.). They have reported that early medical postulates have incorporated the notion of temporal ...
Vianelli N - - 1998
Severe neonatal thrombocytopenia occurs in about 15% of deliveries from women with immune thrombocytopenic purpura (ITP). Conflicting data exist about the real usefulness of percutaneous umbilical blood sampling (PUBS) in evaluating the fetal platelet count. We report successful experience, using PUBS, in the management of 12 pregnant women with ITP.
Young E D - - 1998
Ultraviolet laser microprobe analyses of a calcium-aluminum-rich inclusion (CAI) from the Allende meteorite suggest that a line with a slope of exactly 1.00 on a plot of delta (17)O against delta (18)O represents the primitive oxygen isotope reservoir of the early solar nebula. Most meteorites are enriched in (17)O and ...
Highman T J - - 1998
OBJECTIVE: We sought to evaluate the longitudinal changes in maternal serum leptin concentrations, body composition, and resting metabolic rate during pregnancy. STUDY DESIGN: Ten women were evaluated before pregnancy, in early pregnancy (12 to 14 weeks), and in late pregnancy (34 to 36 weeks). Leptin concentrations were measured by radioimmunoassay, ...
Gilbert V E - - 1997
Early physicians diagnosed pleural effusion by detecting shifting percussion dullness of the chest. However, the lateral decubitus positions have not been routinely used to distinguish this condition from atelectasis or pneumonia. In this report, postural alterations of percussion dullness established the diagnosis of pleural effusion in a 49-year-old patient with ...
Bastian L A LA Department of Internal Medicine, Duke University Medical Center, Durham, NC, USA. - - 1997
This review addresses a common problem facing the clinician: "When treating or evaluating a woman of childbearing years, what is the value of historical or physical examination features in determining the probability of early pregnancy?" We focus on the clinical examination findings that may help the clinician rule in or ...
Byrne J D - - 1997
Idiopathic thrombocytopenic purpura in pregnancy is usually treated with prednisone or intravenous immune globulin. Because of the fetal risk, there are few good alternatives for women who do not respond. We report a case of refractory idiopathic thrombocytopenic purpura successfully treated with pulsed high-dose oral dexamethasone, which offered ease of ...
Waters M R - - 1997
Lower Paleolithic artifacts have been recovered from a single occupation surface within stratified deposits at Diring Yuriakh, an archaeological site in central Siberia. Thermoluminescence age estimates from eolian sediments indicate that the cultural horizon is greater than 260,000 years old. Diring Yuriakh is an order of magnitude older than documented ...
Borzini P - - 1997
BACKGROUND AND OBJECTIVES: Autoantibodies to CD36, a platelet glycoprotein, have been found in patients with thrombotic thrombocytopenic purpura, and in those with lupus-like anticoagulant with thrombotic complications. MATERIALS AND METHODS: Conventional hematologic and laboratory methods were used. The patient was a pregnant woman, who had had two early fetal losses ...
Ahmad M - - 1996
In a screen for early-flowering mutants, a number of mutants that were early flowering under both short and long days were isolated. One such mutant, pef1, was selectively insensitive to both red and far-red light in the inhibition of hypocotyl elongation response; a classic phytochrome phenotype mediated by both PHYA ...
Hull P - - 1996
Pharmaceutical companies often maintain a bibliographic database of published articles on their products. Although such databases share the common purpose of providing the company with a centralized source of published information, the databases themselves vary in scope, uses, and technologies. In order to explore the current status of these databases, ...
Ezra Y - - 1996
Thrombotic thrombocytopenic purpura (TTP) is a severe multisystem disorder of unknown pathogenesis, with preference to women. The mortality rate of patients with TTP was 90% until the introduction of plasma therapy that increased the survival rate to 70-80%, with minimal or no sequelae. Of the survivors, 30-60% suffer from relapses, ...
1 2 3 4 5 6 >