The ability to terminate crying (quieting) without intervention was studied from 0 to 18 weeks. Two groups were involved: 11 newborns during the first hour after birth and a longitudinal group of 14 infants seen every 3 weeks from 3 to 18 weeks. Most newborns who cried showed quieting with ...

The newborn guanaco (Lama quanaco e ) is covered by an extra fetal membrane. It shares this characteristic with the newborns of old-world camelids. This membrane, which is lubricated by the watery amnionic fluid typical for camelids, facilitates the delivery of the conceptus. the newborn gets rid of this membrane ...

Skin disease in pregnancy generally produces increased concern among attending physicians. Not only is the diagnosis often a problem but the safety of the therapy may also be a concern. The author of this article presents three common skin problems and their treatments to illustrate the general principles used in ...

Newer techniques for diagnosing early pregnancy have shown that post-implantation embryo loss may be four times the accepted rate of 15%-20%. This article describes various causes of spontaneous abortion and its clinical evaluation and treatment, and proffers suggestions for answering the questions of women who have experienced this loss.

Purified lipopolysaccharide (LPS) obtained from isolates of Campylobacter fetus ss. fetus and Campylobacter jejuni impaired fetal development when administered to mice on day 13 of pregnancy. Strikingly more fetal resorption was produced by C. jejuni LPS than by similar amounts of C. fetus ss. fetus LPS. Three of the four ...

Transport technology in the last 35 years has created new environmental frontiers in which family physicians are, and will continue to be, involved both in research and in administering patient care. Some frontiers address basic physiological problems that cross over into others. In a series of four articles, the author ...

The role of endotoxin in newborn septic shock is reviewed. Metabolic and cardiovascular changes, as known to us, are described with special emphasis that the newborn is not a "small adult." Developmental or maturational changes are hypothesized to be the major cause of these differences between age groups. Finally, it ...

Over the last 35 years transport technology has created new environmental frontiers in which family physicians are, and will continue to be, involved both in research and in administering patient care. Some frontiers address basic physiological problems that cross over into others. In a series of four articles, the author ...

Over the last 35 years, transport technology has created new environmental frontiers in which family physicians are, and will continue to be, involved both in research and in administering patient care. Some frontiers address basic physiological problems that cross over into others. In a series of four articles, the author ...

C5a is an 11,000-Da complement-derived inflammatory glycoprotein that has been shown to mediate inflammatory reactions in vitro as well as in vivo in human skin. The C5a degradation product, C5a des Arg, is rapidly formed after exposure of C5a to serum carboxypeptidase N and may represent the relevant C5-derived inflammatory ...

In Canada today, the average family size is declining and the expectation of most couples regarding health for their children is rising. These trends are placing more "value" on each pregnancy. Couples who are concerned about future pregnancies are now more often seeking advice relating to their family history and ...

Over the last 35 years transport technology has created new environmental frontiers, both in research and in the administration of patient care, in which family physicians are, and will continue to be, involved. Some of these frontiers address basic physiological problems that become interconnected with others. The author describes six ...

A male newborn presented at birth with marked skin fragility and widespread erosions of the face, scalp, trunk and extremities. Abnormal associated findings included: cleft palate, hypoplastic low-set ears, bilateral synechiae of the first and second toes, incomplete fusion of both eyelids, and dystrophic nails. There was no evidence of ...

An 1,860 g baby girl was born spontaneously after a 38 weeks pregnancy with important foetal hypotrophy and died at 6 weeks of life. She had an inverted duplication of a small part of the short arm of chromosome 1p:46, XX, inv dup(1) (pter p31::p11p13::p31 ter). This observation is compared ...

The effect of milrinone on mechanical function was studied in the isolated arterially perfused heart of the fetal (28th day of gestation) and newborn rabbits. The inotropic effect of milrinone in the fetus was significantly less than in the newborn. After milrinone infusion, myocardial cyclic AMP levels increased significantly in ...

The ability of peripheral blood mononuclear cells derived from newborn infants, their mothers and healthy adults to produce interleukin 1 (IL-1) was examined. It was found that newborn and maternal mononuclear cells have a normal capacity to produce IL-1. In addition, a lower stimulatory activity of IL-1 production was found ...

This trial concerned an injury in a newborn child which was allegedly caused by an accident involving the mother during her pregnancy. The trial is widely accepted as a turning-point in law related to fetal injury, conferring the right of a child to claim compensation at birth for injuries inflicted ...

To determine the effects of aerobic fitness on pregnancy and the newborn, 20 primigravid subjects were studied throughout gestation and immediately postpartum. The subjects were classified as trained (T = 10) or untrained (UT = 10) based on the heart rate response to submaximal cycle ergometry testing done in each ...

The disposition of the N-cyanoethyl analogue of tranylcypromine (TCP) and the TCP formed from it have been studied in the rat brain following intraperitoneal (ip) administration (0.1 mmol/kg) and the resultant data compared with those obtained following an equimolar dose of TCP. Brain concentrations of the neurotransmitter amines dopamine (DA) ...

A chronic suppression of Igh-1b and Igh-3b (IgG2a and IgG2b of b haplotype) allotype expression has been induced by injecting T splenocytes from normal BALB/c or BC8 mice into newborn F1 hybrids of appropriate Igh congenic strains: BALB/c into (BALB/c Igha X CB20 Ighb)F1 and BC8 into (BC8 Igha X ...

Pre-term neonates are at increased risk for neurological dysfunction. Several investigators have found scalp recorded somatosensory evoked potential studies (SSEPs) after median nerve stimulation useful in the evaluation of newborn infants with asphyxiation and the effects of other adverse prenatal and perinatal factors. In order to evaluate the entire developing ...

Immunity against tetanus in newborn and in mother-newborn couples was studied in a sample of population from the Siena area, Italy. Mother-newborn antitetanus antibody transfer and the decrease of passively acquired antitoxin, in newborn after birth, were evaluated too. Antitetanus immunity was detected by a passive haemagglutination assay. A high ...

This report describes a new fetal hemoglobin variant, Hb F-Xinjiang, which was observed in a newborn baby of the Han nationality. Its electrophoretic mobility at pH 8.6 was slower than that of Hb D. Structural analyses identified the variant as A gamma T25(B7)Gly----Arg. Heat stability test showed that the variant ...

The aspartate aminotransferase (AST) and alanine aminotransferase (ALT) serum activities were evaluated in the first 12 hrs of life in 26 newborns small-for-gestational age, and correlated with birth weight and gestational age. We found a positive correlation between the ALT serum activity and both birth weight and gestational age of ...

Applications of electromyographic and endoscopic manometric techniques in experimental and clinical studies have enhanced our knowledge of the normal physiology and motility disturbances of the sphincter of Oddi. The sphincter of Oddi has an active role in coordinating the time and rate of secretion of biliopancreatic juice into the duodenum. ...

By age 16 one in three adolescents have experienced sexual intercourse. Because one-third of these sexually active teens never use contraception, they have a five-times greater risk of pregnancy than teenagers who take contraceptive measures. In 1982, one in 23 Canadian teenage girls became pregnant. Teenagers' reasons for not using ...

Acetylcholinesterase staining and double labeling techniques were used to study the subdivision of the lateral posterior nucleus (LP) of the thalamus in newborn kittens. The LP was divided into acetylcholinesterase-positive and -negative parts, which densely project onto the lateral and medial banks of the lateral suprasylvian area, respectively. These results ...

A newborn with female pseudohermaphroditism (profound masculinization of the external genitalia and preservation of the internal female genitalia) is presented. During pregnancy progressive hirsutism was noted in the mother, and polycystic ovaries were found at cesarean section. The serum testosterone level in the cord blood was elevated markedly (1,232 ng./dl). ...

This article describes an obstetrical chart review that covered a seven-year period from April 30, 1978 to March 31, 1984. This review includes both pre- and intra partum transfers and involves two main topics: referral pattern and rate of intervention during labour. The practice was involved in 60% of all ...

Most standard obstetrical and gynecological textbooks ignore the subject of sexuality during and after pregnancy, and physicians who practise obstetrics tend to pay scant attention to this aspect of their patients' well-being. Since 1966, when Masters and Johnson's studies were published, relatively little information about pregnancy and sexuality has appeared ...

Estrogen and progesterone receptors were characterized in the fetal and newborn vagina of guinea pig. The concentrations of estrogen receptor (total sites, cytosol plus nuclei) which were very high [7090 +/- 1700 (+/- SD) fmol/mg DNA] in the fetal vagina (62-64 days gestation) decreased significantly after birth and increased slightly ...

Immunoglobulin G antibodies are the most frequent type of red blood cell isoantibodies. They possess the ability to traverse the placenta and may cause hemolytic disease in newborn infants. Of the four subclasses, IgG1 and IgG3 are effective at binding erythrocytes to monocyte-macrophages and therefore are potentially destructive to erythrocytes. ...

A fifth-month fetus and a newborn with amniogenic band anomalies were examined at autopsy. Both specimens were obtained from women who had undergone oophorectomy during early pregnancy. The dead male fetus was aborted spontaneously, and had a micrognathia, a right club foot, and a constriction ring on the left lower ...

Free calcium ion concentration (mmol/l) and pH were determined in whole blood using a semiautomatic electrode system (ICA-1 Radiometer, Copenhagen, Denmark) in 37 normal women, 90 pregnant women (30 from each trimester of gestation), 28 mothers at delivery and their respective newborns. The blood samples from normal controls, pregnant women, ...

Tyrosine hydroxylase-(TH)-like and Substance-P-(SP)-like immunoreactivity has been tentatively located in the retina of 24-29 week-old fetuses, newborn infants, 2-8-month-old children, and adults. The first TH immunoreactive cells were demonstrated as early as 24 weeks of fetal life, while SP immunoreactivity appeared a little later, between 24 and 29 weeks. Thus ...

This article has presented a psychoanalytic perspective on the process of becoming a father. It began with a discussion of the neglect of the father during pregnancy and briefly considered evidence as to the unique contributions made by fathers of the newborn. Nine psychodynamically based wishes emerging throughout the developmental ...

The authors describe their experience with methadone treatment in pregnancy. Thirteen abuser pregnant women were studied under defined obstetrical and toxicological protocol. Newborns were also included in this study. In some cases a complete adherence to therapeutic program, allowing labour under very low methadone dosage (5 mg/day), minimized toxicological neonatal ...

Newborn mice exposed to 241Am or 237Pu during gestation and whose mothers were given Zn-DTPA at various times before parturition contained less radioactivity than comparable newborn mice given identical 241Am or 237Pu exposure without Zn-DTPA treatment of the mothers. There was no net increase in radionuclide transfer from mothers to ...

A model for congenital syphilis in rabbits was developed based on multiple intravenous injections of pregnant does with high concentrations of Treponema pallidum. A total of 48 pregnant does and 394 newborns were evaluated. Indications of in utero infection included a 7- to 10-fold increase in fetal mortality and a ...

We compared simultaneous healing processes in fetal, newborn, and maternal rabbits using a miniaturized wound cylinder of expanded Gore-Tex tubing. The tubing was placed subcutaneously in fetal and maternal rabbits on day 23 of pregnancy (term = 31 to 32 days), and in 7-day-old newborn rabbits. At specific intervals, the ...

The substrate and oxygen uptake by some organs in intact developing animals has been described, however, the kidney has not been studied. To examine substrate and oxygen uptake by the kidney, we implanted polyvinyl catheters into the renal vein, descending aorta, inferior vena cava, and urinary bladder of 11 fetal ...

We report a case of an extremely large granular cell epulis situated on the maxillary alveolar ridge of a newborn. It obstructed the infant's mouth and caused polyhydramnios. The lesion was detected in utero by ultrasonography and removed after birth in the delivery room, with satisfactory results. It is evident ...

A new method of measuring bleeding time using an Autolet device is described. Normal ranges of bleeding time and volume of blood used in the test have been defined in a population including preterm babies. Abnormal values have been shown in newborns with a variety of problems, and an abnormality ...

Following i.v. injection of Nb-95 into pregnant rats, fetuses and newborns were dissected and measured for radioactivity after several time intervals. At any time only a small quantity of the administered radioactivity was transferred to fetus and newborn and the fetal tissue concentrations were always lower than the maternal ones. ...

The incidence of isolated, nonsyndromatic craniosynostosis in a newborn population was found to be 0.6 per 1,000 live births. The distribution by anatomic types was metopic suture, 50%; sagittal suture, 28%; coronal suture, 16.5%; and lambdoid suture, 5.5%. We found a higher incidence of trigonocephaly than has been reported previously.

Following its addition to a suspension of rabbit neutrophils, leukotriene B4 is rapidly (less than 1 min) recovered from the cytoskeletal fraction (Triton X-100 insoluble pellet) of these cells. The association of leukotriene B4 with the cytoskeleton can be competed with by leukotriene B4 itself and by 20-OH leukotriene B4 ...

Newborn and maternal hair samples were obtained from subjects occupationally exposed to heavy metals and from matched controls. The geometric means of levels of cadmium and lead in hair from exposed mothers and of cadmium in hair from transplacentally exposed newborns were twice as high as levels present in samples ...

Serum thyroglobulin (Tg) was measured in the cord blood of 635 newborns and serum thyroxine (T4) reverse triiodothyronine (rT3), TSH and T3 were measured in about 200 of them. Cord Tg was detectable in all newborns with a mean +/- SE value (50 +/- 1.3 ng/ml) higher than that found ...

The data implicating prostaglandin synthesis inhibitors as an etiology for PPHN are reviewed. Consideration is given to the pharmacology of prostaglandin synthesis inhibitors in the fetus and newborn, the role of prostaglandins in the fetal and neonatal circulation, and the effect of closure of the ductus arteriosus on the fetal ...

In the dorsal epidermis of both C57BL/10J (black, BB) and C57BR/cdJ (brown, bb) mice, the number of melanocytes positive to the dopa reaction (melanocyte population) increases from birth to day 3 or 4, and then gradually decreases. However, the number of melanoblasts plus melanocytes positive to the combined dopa-premelanin reaction ...