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Burger Huibert H Department of General Practice, University of Groningen, University Medical Centre Groningen, Hanzeplein 1, 9700 RB, Groningen, The Netherlands, - - 2015
There is ample evidence from observational prospective studies that maternal depression or anxiety during pregnancy is a risk factor for adverse psychosocial outcomes in the offspring. However, to date no previous study has demonstrated that treatment of depressive or anxious symptoms in pregnancy actually could prevent psychosocial problems in children. ...
Essex Holly N HN Mental health and Addiction Research Group, Department of Health Sciences, University of York, Heslington, York, YO10 5DD, UK - - 2014
Smoking during pregnancy is the most important, preventable cause of adverse pregnancy outcomes including miscarriage, premature birth and low birth weight, with huge financial costs to the NHS. However, there are very few published economic evaluations of smoking cessation interventions in pregnancy and previous studies are predominantly US-based and do ...
Khan Nabeel N University of Pennsylvania Perelman School of Medicine, Department of Gastroenterology , Philadelphia, PA , USA - - 2014
Introduction: The highest incidence of inflammatory bowel disease (IBD) is seen between the second and fourth decades of life, which is the most fertile age for women. Increased disease activity has been shown to effect female fertility and pregnancy outcomes, stressing the need for drugs that can safely induce and ...
Diamond-Smith Nadia G NG Postdoctoral fellow, Global Health Group, University of California, San Francisco, 50 Beale Street, 12th Floor, San Francisco, CA 94105.. - - 2014
Although the rate of contraceptive use in France is high, more than one-third of pregnancies are unintended. We built a dynamic microsimulation model that applies data from the French COCON study on method switching, discontinuation, and failure rates to a hypothetical population of 20,000 women, followed for five years. We ...
Stout T A TA Faculty of Veterinary Medicine, Utrecht University, Utrecht, the - - 2014
Equine pregnancy is characterised by an unusually long pre-implantation period (40 days) during which the conceptus is entirely dependent on uterine secretions for nutrient provision; although glucose is an important nutrient during development post-blastocyst formation, little is known about its transport into the early horse conceptus. Equine embryos are also ...
Elguero Sonia S Division of Reproductive Endocrinology & Infertility, Department of Obstetrics & Gynecology, University Hospitals Case Medical Center , Cleveland, OH , USA - - 2014
Abstract Aim: To investigate the effect of empiric use of luteal phase progesterone supplementation to improve endometrial receptivity in women undergoing treatment with clomiphene citrate in combination with intrauterine insemination (CC-IUI). Design: Retrospective cohort analysis. Setting: University fertility center. Patients: 426 CC-IUI cycles from 292 patients with unexplained infertility. Interventions: ...
Roque Matheus M ORIGEN - Center for Reproductive Medicine, Av Rodolfo de Amoedo, 140 - Barra da Tijuca, 22520-350, Rio de Janeiro, Rio de Janeiro, Brazil, - - 2014
This publication will evaluate the available evidence in the literature comparing fresh embryo transfer (ET) and elective frozen-thawed embryo transfer (FET) regarding the possible interference of controlled ovarian stimulation (COS) in implantation and endometrial receptivity, IVF safety, and obstetric and perinatal outcomes. We performed a review in the literature of ...
Hong Yun-Chul YC Institute of Environmental Medicine, Medical Research - - 2014
The effects on postnatal growth of maternal exposure to low levels of lead during pregnancy have not been well established. In addition, information is limited regarding the protective effect of dietary calcium intake during pregnancy against the effect of lead for fetal and postnatal growth. We investigated the relationship between ...
Lee Jessica J University of Pittsburgh, Department of Obstetrics, Gynecology and Reproductive - - 2014
To assess how a checklist reminding clinicians to deliver a bundled intervention affects contraceptive knowledge and use 3 months after women seek walk-in pregnancy testing. Pre-intervention, an inner-city family planning clinic provided unstructured care; during the intervention period, clinic staff used a checklist to ensure women received needed services. Women ...
Selmeczi A - - 2014
Pregnancy is associated with increased risk of venous thromboembolism, especially in the presence of thrombophilia. However, there is no consensus on the optimal approach for thromboprophylaxis in this population. Recent evidence suggests that thrombin generation correlates with the overall procoagulant state of the plasma. Our aim was to evaluate thrombin ...
Ion Rachel R Obstetrics & Gynaecology, St Michael's Hospital, Bristol, United Kingdom - - 2014
Premature birth is a significant global problem and the leading cause of newborn deaths. Tobacco smoking has been associated with premature birth for over 50 years. The mechanisms through which smoking exerts its effects on pregnancy outcomes remain unclear. In this review, we discuss rates of prematurity and smoking in ...
Wen Huanhuan H Obstetrics and Gynecology/TCM, Fertility Clinic, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 725 South Wanping Road, Shanghai, 200032, China, - - 2014
Salpingitis is a major cause of infertility. Clinical studies about hydrotubation combined with Chinese herbal medicine (CHM) for salpingitic infecundity are increasing, while systematic reviews about its efficacy remain inexistent. Assessing the effectiveness of hydrotubation combined with CHM for salpingitic infecundity. Randomized controlled trials were retrieved from different seven databases. ...
Nardelli Alexa A - - 2014
Over the years, IVF/ICSI protocols have continued to evolve with efforts to improve outcomes. As a result, treatment success may be related to certain procedural factors, including number of embryos transferred and stage at which they are transferred. This review aims to assess the safety and effectiveness of IVF/ICSI in ...
Harper Lorie M LM The Maternal-Fetal Medicine Division, Department of Obstetrics and Gynecology, Center for Women's Reproductive Health at the University of Alabama at Birmingham, Birmingham, - - 2014
To determine the most cost-effective delivery timing in pregnancies complicated by gastroschisis using a decision-analytic model. We created a decision analytic model to compare planned delivery at 35, 36, 37, 38, & 39 weeks. Outcomes considered were stillbirth, death within 1 year of life, & respiratory distress syndrome (RDS). Probability ...
Ruifrok Anneloes E - - 2014
Pregnant women who gain excess weight are at risk of complications during pregnancy and in the long term. Interventions based on diet and physical activity minimise gestational weight gain with varied effect on clinical outcomes. The effect of interventions on varied groups of women based on body mass index, age, ...
Konomi Juna V JV Nutrition and Health Sciences, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, USA Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Emory University, Emory + Children's Healthcare of Atlanta Center for Developmental Lung Biology, Atlanta, GA 30322, - - 2014
(a) Establish the minimum number of weeks of chronic ethanol ingestion needed to perturb zinc homeostasis, (b) Examine intracellular zinc status in the alveolar macrophages (AMs) when ethanol ingestion is combined with pregnancy, (c) Investigate whether in vitro zinc treatment reverses the effects of ethanol ingestion on the AM. C57BL/6 ...
Yefet Enav E Resident, Department of Obstetrics & - - 2014
Quinolones and fluoroquinolones are highly efficient antibiotics. However, concerns regarding possible harmful effects have limited their use during pregnancy. Nevertheless, accumulating clinical data suggest that they may be safe during pregnancy. This review aimed to explore the mechanisms of action of the quinolones and fluoroquinolones, which set the stage for ...
Pope Eliza - - 2014
I have a pregnant patient who regularly consumes sugar substitutes and she asked me if continuing their use would affect her pregnancy or child. What should I tell her, and are there certain options that are better for use during pregnancy? Although more research is required to fully determine the ...
Bracamonte-Baran William - - 2014
Non-inherited maternal antigens (NIMA) are those protein products derived from polymorphic genes that the mothers express but not the offspring. During normal human pregnancy, a bidirectional regulation occurs in such a way that the maternal immune system tolerates the inherited paternal antigens (IPA) expressed by the fetus and the developing ...
Khan Nabeel N University of Pennsylvania Perelman School of Medicine, Department of Gastroenterology , Philadelphia, PA , USA - - 2014
Introduction: The highest incidence of inflammatory bowel disease (IBD) is seen between the second and fourth decades of life, which is the most fertile age for women. Increased disease activity has been shown to effect female fertility and pregnancy outcomes, stressing the need for drugs that can safely induce and ...
Knox Robert V RV Department of Animal Sciences, University of Illinois, 1207 West Gregory Avenue, Urbana, IL, USA 61801. Electronic address: - - 2014
Frozen-thawed boar sperm (FTS) has reduced fertility compared to liquid semen. Exogenous prostaglandin administered at insemination has been reported to improve cases of low fertility. This experiment tested the effect of number of FTS and addition of prostaglandin (PGF2α) on fertility. The experiment was performed in replicates using weaned sows ...
Pompili Maurizio M Department of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Center, Sant'Andrea Hospital, Sapienza University of Rome, 1035-1039, Via di Grottarossa, 00189, Rome, - - 2014
Pharmacological treatment of severe psychiatric disorders during pregnancy is complicated by the potential harmful effects of treatment for the fetus. Electroconvulsive therapy (ECT) has been demonstrated to be effective for the treatment of several mental disorders. The aim of this study was to investigate the safety of ECT in the ...
Washington Chantel I CI Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address: - - 2014
To determine if immediate postpartum (PP) intrauterine device (IUD) placement prevents pregnancy and is cost-effective compared with routine placement. We developed a decision-analysis model to determine the number of pregnancies prevented and the cost-effectiveness of immediate PP IUD placement defined as within the first 10 minutes of placental expulsion compared with ...
Garor Roni R Infertility and IVF Unit, Beilinson's Women Hospital, Rabin Medical Center, Petach Tikva, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, - - 2014
To assess the impact of oocyte aspiration, denudation, and sperm injection timing in relation to oocyte hCG exposure time on intracytoplasmic sperm injection (ICSI) outcome. Cohort study. Tertiary medical center. A total of 614 consecutive ICSI cycles were performed in 421 patients aged <38 years with at least three aspirated oocytes ...
Odedra Katy Mara KM Imperial College Healthcare NHS Trust, St Mary's Hospital, - - 2014
Rhinitis, a condition involving inflammation and irritation of the nasal membranes, is a common condition that can be allergic or non-allergic in origin. Pre-existing rhinitis can worsen during pregnancy, and new rhinitis can occur. Rhinitis has a significant effect on quality of life. Where rhinitis co-exists with asthma, it is ...
De Long Nicole E NE McMaster University, Department of Obstetrics and Gynecology , RM HSC-3N52, 1280 Main Street West, Hamilton, Ontario, L8S 4K1 , Canada +1 905 525 9140 ext. 22130 ; +1 905 524 2911 ; - - 2014
Introduction: Worldwide, 10 to 35% of pregnant women smoke. It is clear that smoking cessation has positive impacts for both the mother and child, yet many women are still unable to quit due to the addictive properties of nicotine. There are limited data surrounding their safety and efficacy in pregnancy. ...
Servey Jessica J Uniformed Services University of the Health Sciences, Bethesda, MD, - - 2014
Many pregnant women take over-the-counter (OTC) medications despite the absence of randomized controlled trials to guide their use during pregnancy. Most data come from case-control and cohort studies. In 1979, the U.S. Food and Drug Administration began reviewing all prescription and OTC medications to develop risk categories for use in ...
Easterling Thomas R TR Department of Obstetrics and Gynecology, University of Washington, Seattle, WA 98195. Electronic address: - - 2014
Hypertension in pregnancy remains a significant public health problem. Pharmacological management of blood pressure in pregnancy is impacted by changes in maternal drug disposition and by the pharmacodynamic effects of specific agents. This article will review the impact of pregnancy on pathways of drug elimination and the associated clinical implications, ...
Fugel Hans-Joerg - - 2014
New techniques in assessing oocytes and embryo quality are currently explored to improve pregnancy and delivery rates per embryo transfer. While a better understanding of embryo quality could help optimize the existing "in vitro fertilization" (IVF) therapy schemes, it is essential to address the economic viability of such technologies in ...
Bayer Otmar - - 2014
Gestational weight gain (GWG) has been shown to be a risk factor for overweight in offspring.Aim of this study was to quantify the contributions of trimester-specific and total GWG on offspring's BMI and waist circumference (WC). This is of interest for the design of interventions targeted at women showing a ...
Visser Gerard H A GH Department of Obstetrics, University Medical Center, Utrecht, The - - 2014
Worldwide, there is a rapid increase in deliveries by cesarean section. The large differences among countries, from about 16% to more than 60%, suggest that the cesarean delivery (CD) rate has little to do with evidence-based medicine. In this review, the background for the increasing CD rate is discussed as ...
McNicholas Colleen C Division of Clinical Research, Washington University School of Medicine, St Louis, - - 2014
The Contraceptive CHOICE Project was a prospective cohort study of 9256 women in the St Louis area. The project provided no-cost reversible contraception to participants for 2 to 3 years with the goal of increasing uptake of long-acting reversible contraception and decreasing unintended pregnancy in the area. This manuscript will ...
Nevers Will - - 2014
I have a 30-year-old patient who had a kidney transplant 2 years ago. She is now planning a pregnancy. She has been treated with tacrolimus since her transplant. Will it be safe for the fetus if she continues to take it during the pregnancy or should she switch to a ...
Kurzynska A A Department of Animal Physiology, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland. - - 2014
In the present study we investigated the effect of peroxisome proliferator activated receptor (PPAR) ligands on progesterone (P4) and 17β-estradiol (E2) secretion and 3b-hydroxysteroid dehydrogenase/Δ(5)-Δ(4) isomerase (3β-HSD) mRNA abundance in porcine corpora lutea (CL) collected on days 10-12 and 14-16 of the estrous cycle or pregnancy. The PPAR agonists reduced ...
Suri Rita R UCLA Mood Disorders Research Program, 300 Medical Plaza, Ste 1544, Los Angeles, CA 90095-7057 - - 2014
The authors reviewed the published literature on the acute and long-term neurobehavioral effects on infants and children of either in utero exposure to maternal depression or in utero exposure to antidepressants. The PubMed electronic database was searched to locate 292 English-language studies from the first available year to October 2013 ...
Halpern Vera V Clinical Sciences, FHI 360, 359 Blackwell St, Suite 200, Durham, North Carolina, USA, - - 2014
Repeated use of postcoital hormonal contraception is not currently recommended due to the higher risk of side effects and lower contraceptive effectiveness compared to other modern methods of contraception. However, emerging evidence indicates renewed interest in a regular coitally-dependent method of oral contraception. We evaluated the existing data on safety ...
Korgavkar K K University of Michigan Medical School, Ann Arbor, - - 2014
Striae gravidarum (SG), or stretch marks developing during pregnancy, affect up to 90% of women. While not medically dangerous, SG can be disfiguring, causing emotional and psychological distress. However, studies specifically addressing the prevention of SG, especially during pregnancy, are sparse. Furthermore, the molecular pathogenesis of SG is unclear and ...
Micks Elizabeth E Department of Obstetrics and Gynecology, University of Washington, Seattle, - - 2014
More than 1 million abortions are performed annually in the United States. Women presenting for abortion care are often motivated by the pregnancy to use effective contraception; they are also at high risk for repeat unintended pregnancy. For these reasons, abortion represents an optimal time to initiate effective contraception. There ...
Cleland Kelly K *Office of Population Research, Princeton University, Princeton, New Jersey †Gynuity Health Projects ‡Family Care International, New York, New - - 2014
Several options for emergency contraception are available in the United States. This article describes each method, including efficacy, mode of action, safety, side effect profile, and availability. The most effective emergency contraceptive is the copper intrauterine device (IUD), followed by ulipristal acetate and levonorgestrel pills. Levonorgestrel is available for sale ...
Tong Stephen S Translational Obstetrics Group, University of Melbourne, Department of Obstetrics and Gynaecology, Mercy Hospital for Women, Heidelberg, 3084, - - 2014
Ectopic pregnancies are a serious gynaecological emergency that can be fatal. As such, prompt diagnosis, and safe timely treatment is essential. Here we review the literature on the development of molecularly targeted diagnostics and therapeutics for ectopic pregnancy. A blood-based biomarker that accurately identifies an ectopic pregnancy could be used ...
Moreau Caroline C Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Gender, Sexual and Reproductive Health, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, Kremlin Bicêtre, France. Electronic address: - - 2014
To evaluate the effect of question wording on national estimates of pregnancy intentions. Data drawn from a national probability survey. The FECOND study in France in 2010. 5,272 women and 3,373 men who reported 11,603 pregnancies. Participants randomly assigned to answer 1 of 2 questions on whether they had planned or ...
Lamont Harriet F HF University of Southampton, Southampton General Hospital, Faculty of Medicine , Tremona Road, Southampton, SO16 6YD , - - 2014
Introduction: The extent of antibiotic use in pregnancy remains unknown but may occur in > 40% of pregnant women for various indications, at different gestational ages from different sources. Areas covered: Antibiotic resistance, alterations to the neonatal immune system causing allergy, asthma and atopic disease in later life and teratogenicity. ...
Garcia-Ispierto Irina I Department of Animal Production, Agrotecnio Center, University of Lleida, Lleida, - - 2014
This study compares in two experiments the responses of lactating dairy cows to four different progesterone-based protocols for fixed-time artificial insemination (FTAI) in terms of their effects on follicular/luteal dynamics and fertility. The protocols consisted of a progesterone intravaginal device fitted for five days, along with the administration of different ...
Muggli Evelyne - - 2014
Despite extensive research, a direct correlation between low to moderate prenatal alcohol exposure (PAE) and Fetal Alcohol Spectrum Disorders has been elusive. Conflicting results have been attributed to a lack of accurate and detailed data on PAE and incomplete information on contributing factors. The public health effectiveness of policies that ...
D'Ovidio Valeria V GI Unit, Department of Internal Medicine and Medical Specialties, Policlinico Umberto I, University of Rome "La Sapienza", Sapienza, University of Rome, - - 2014
Inflammatory bowel disease characteristically affects young adults in their reproductive ages. Thus the medication used for the treatment of active disease should not compromise fertility and, also, should not have teratogenic effect on baby. A lot of data are available about effects of steroids, antibiotics, and mesalazine but no data ...
St-Pierre Normand R NR Department of Animal Science, College of Food Agricultural and Environmental Sciences, The Ohio State University, Columbus, OH - - 2014
Objective-To provide an updated evaluation of the efficacy and safety of sometribove zinc suspension (rbST-Zn), a form of recombinant bovine somatotropin, in lactating dairy cows. Design-Meta-analysis. Sample-26 studies published in peer-reviewed journals or reviewed by a regulatory agency. Procedures-To be included, a study had to involve the use of the ...
Framarino-Dei-Malatesta M M Department of Gynecologic-Obstetrical and Urologic Sciences, University of Rome Sapienza, Rome, Italy. Electronic address: - - 2014
Mammalian target of rapamycin inhibitors (mTORi) are a promising new family of immunosuppressive drugs. No teratogenic effects have been reported to date. Their lipid and glucidic effects should not be underestimated, however, especially during pregnancy. Moreover, mTORi may affect fetal growth by mTOR placental activity. Our purpose was to highlight ...
Ben-Chetrit Eldad E Rheumatology Unit, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. - - 2014
To review the current available literature on the mutual effect of pregnancy or contraceptives and Behçet's disease (BD) in order to guide our patients more wisely before they take contraceptives or decide to conceive. We performed a systematic review of the literature regarding the above issues using PubMed, Cochrane and ...
Kovac Jason Ronald JR Urology of Indiana, Carmel, - - 2014
Varicoceles are a common cause of male infertility; repair can be accomplished using either surgical or radiological means. We compare the cost-effectiveness of the gold standard, the microsurgical varicocele repair (MV), to the options of a nonmicrosurgical approach (NMV) and percutaneous embolization (PE) to manage varicocele-associated infertility. A Markov decision-analysis ...
Yoon Hye Jin HJ Maria Reproductive Center, Department of Obstetrics and Gynecology, Maria Fertility Hospital, Seoul, - - 2014
The effect of artificial oocyte activation (AOA) with a calcium ionophore on intracytoplasmic morphologically selected sperm injection (IMSI) was examined in patients with histories of repeated failed implantation attempts. Four singleton pregnancies and one twin pregnancy were obtained after embryos transfer (5/14, 35.7%). Therefore, AOA combined with IMSI can be ...
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