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Burger Huibert H Department of General Practice, University of Groningen, University Medical Centre Groningen, Hanzeplein 1, 9700 RB, Groningen, The Netherlands, - - 2015
There is ample evidence from observational prospective studies that maternal depression or anxiety during pregnancy is a risk factor for adverse psychosocial outcomes in the offspring. However, to date no previous study has demonstrated that treatment of depressive or anxious symptoms in pregnancy actually could prevent psychosocial problems in children. ...
Easterling Thomas R TR Department of Obstetrics and Gynecology, University of Washington, Seattle, WA 98195. Electronic address: - - 2014
Hypertension in pregnancy remains a significant public health problem. Pharmacological management of blood pressure in pregnancy is impacted by changes in maternal drug disposition and by the pharmacodynamic effects of specific agents. This article will review the impact of pregnancy on pathways of drug elimination and the associated clinical implications, ...
Fugel Hans-Joerg - - 2014
New techniques in assessing oocytes and embryo quality are currently explored to improve pregnancy and delivery rates per embryo transfer. While a better understanding of embryo quality could help optimize the existing "in vitro fertilization" (IVF) therapy schemes, it is essential to address the economic viability of such technologies in ...
Bayer Otmar - - 2014
Gestational weight gain (GWG) has been shown to be a risk factor for overweight in offspring.Aim of this study was to quantify the contributions of trimester-specific and total GWG on offspring's BMI and waist circumference (WC). This is of interest for the design of interventions targeted at women showing a ...
Visser Gerard H A GH Department of Obstetrics, University Medical Center, Utrecht, The - - 2014
Worldwide, there is a rapid increase in deliveries by cesarean section. The large differences among countries, from about 16% to more than 60%, suggest that the cesarean delivery (CD) rate has little to do with evidence-based medicine. In this review, the background for the increasing CD rate is discussed as ...
McNicholas Colleen C Division of Clinical Research, Washington University School of Medicine, St Louis, - - 2014
The Contraceptive CHOICE Project was a prospective cohort study of 9256 women in the St Louis area. The project provided no-cost reversible contraception to participants for 2 to 3 years with the goal of increasing uptake of long-acting reversible contraception and decreasing unintended pregnancy in the area. This manuscript will ...
Nevers Will - - 2014
I have a 30-year-old patient who had a kidney transplant 2 years ago. She is now planning a pregnancy. She has been treated with tacrolimus since her transplant. Will it be safe for the fetus if she continues to take it during the pregnancy or should she switch to a ...
Halpern Vera V Clinical Sciences, FHI 360, 359 Blackwell St, Suite 200, Durham, North Carolina, USA, - - 2014
Repeated use of postcoital hormonal contraception is not currently recommended due to the higher risk of side effects and lower contraceptive effectiveness compared to other modern methods of contraception. However, emerging evidence indicates renewed interest in a regular coitally-dependent method of oral contraception. We evaluated the existing data on safety ...
Korgavkar K K University of Michigan Medical School, Ann Arbor, - - 2014
Striae gravidarum (SG), or stretch marks developing during pregnancy, affect up to 90% of women. While not medically dangerous, SG can be disfiguring, causing emotional and psychological distress. However, studies specifically addressing the prevention of SG, especially during pregnancy, are sparse. Furthermore, the molecular pathogenesis of SG is unclear and ...
Micks Elizabeth E Department of Obstetrics and Gynecology, University of Washington, Seattle, - - 2014
More than 1 million abortions are performed annually in the United States. Women presenting for abortion care are often motivated by the pregnancy to use effective contraception; they are also at high risk for repeat unintended pregnancy. For these reasons, abortion represents an optimal time to initiate effective contraception. There ...
Cleland Kelly K *Office of Population Research, Princeton University, Princeton, New Jersey †Gynuity Health Projects ‡Family Care International, New York, New - - 2014
Several options for emergency contraception are available in the United States. This article describes each method, including efficacy, mode of action, safety, side effect profile, and availability. The most effective emergency contraceptive is the copper intrauterine device (IUD), followed by ulipristal acetate and levonorgestrel pills. Levonorgestrel is available for sale ...
Tong Stephen S Translational Obstetrics Group, University of Melbourne, Department of Obstetrics and Gynaecology, Mercy Hospital for Women, Heidelberg, 3084, - - 2014
Ectopic pregnancies are a serious gynaecological emergency that can be fatal. As such, prompt diagnosis, and safe timely treatment is essential. Here we review the literature on the development of molecularly targeted diagnostics and therapeutics for ectopic pregnancy. A blood-based biomarker that accurately identifies an ectopic pregnancy could be used ...
Moreau Caroline C Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Gender, Sexual and Reproductive Health, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, Kremlin Bicêtre, France. Electronic address: - - 2014
To evaluate the effect of question wording on national estimates of pregnancy intentions. Data drawn from a national probability survey. The FECOND study in France in 2010. 5,272 women and 3,373 men who reported 11,603 pregnancies. Participants randomly assigned to answer 1 of 2 questions on whether they had planned or ...
Lamont Harriet F HF University of Southampton, Southampton General Hospital, Faculty of Medicine , Tremona Road, Southampton, SO16 6YD , - - 2014
Introduction: The extent of antibiotic use in pregnancy remains unknown but may occur in > 40% of pregnant women for various indications, at different gestational ages from different sources. Areas covered: Antibiotic resistance, alterations to the neonatal immune system causing allergy, asthma and atopic disease in later life and teratogenicity. ...
Garcia-Ispierto Irina I Department of Animal Production, Agrotecnio Center, University of Lleida, Lleida, - - 2014
This study compares in two experiments the responses of lactating dairy cows to four different progesterone-based protocols for fixed-time artificial insemination (FTAI) in terms of their effects on follicular/luteal dynamics and fertility. The protocols consisted of a progesterone intravaginal device fitted for five days, along with the administration of different ...
Muggli Evelyne - - 2014
Despite extensive research, a direct correlation between low to moderate prenatal alcohol exposure (PAE) and Fetal Alcohol Spectrum Disorders has been elusive. Conflicting results have been attributed to a lack of accurate and detailed data on PAE and incomplete information on contributing factors. The public health effectiveness of policies that ...
D'Ovidio Valeria V GI Unit, Department of Internal Medicine and Medical Specialties, Policlinico Umberto I, University of Rome "La Sapienza", Sapienza, University of Rome, - - 2014
Inflammatory bowel disease characteristically affects young adults in their reproductive ages. Thus the medication used for the treatment of active disease should not compromise fertility and, also, should not have teratogenic effect on baby. A lot of data are available about effects of steroids, antibiotics, and mesalazine but no data ...
St-Pierre Normand R NR Department of Animal Science, College of Food Agricultural and Environmental Sciences, The Ohio State University, Columbus, OH - - 2014
Objective-To provide an updated evaluation of the efficacy and safety of sometribove zinc suspension (rbST-Zn), a form of recombinant bovine somatotropin, in lactating dairy cows. Design-Meta-analysis. Sample-26 studies published in peer-reviewed journals or reviewed by a regulatory agency. Procedures-To be included, a study had to involve the use of the ...
Framarino-Dei-Malatesta M M Department of Gynecologic-Obstetrical and Urologic Sciences, University of Rome Sapienza, Rome, Italy. Electronic address: - - 2014
Mammalian target of rapamycin inhibitors (mTORi) are a promising new family of immunosuppressive drugs. No teratogenic effects have been reported to date. Their lipid and glucidic effects should not be underestimated, however, especially during pregnancy. Moreover, mTORi may affect fetal growth by mTOR placental activity. Our purpose was to highlight ...
Ben-Chetrit Eldad E Rheumatology Unit, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. - - 2014
To review the current available literature on the mutual effect of pregnancy or contraceptives and Behçet's disease (BD) in order to guide our patients more wisely before they take contraceptives or decide to conceive. We performed a systematic review of the literature regarding the above issues using PubMed, Cochrane and ...
Kovac Jason Ronald JR Urology of Indiana, Carmel, - - 2014
Varicoceles are a common cause of male infertility; repair can be accomplished using either surgical or radiological means. We compare the cost-effectiveness of the gold standard, the microsurgical varicocele repair (MV), to the options of a nonmicrosurgical approach (NMV) and percutaneous embolization (PE) to manage varicocele-associated infertility. A Markov decision-analysis ...
Yoon Hye Jin HJ Maria Reproductive Center, Department of Obstetrics and Gynecology, Maria Fertility Hospital, Seoul, - - 2014
The effect of artificial oocyte activation (AOA) with a calcium ionophore on intracytoplasmic morphologically selected sperm injection (IMSI) was examined in patients with histories of repeated failed implantation attempts. Four singleton pregnancies and one twin pregnancy were obtained after embryos transfer (5/14, 35.7%). Therefore, AOA combined with IMSI can be ...
Mekinian Arsene A AP-HP, Hôpital Saint-Antoine, service de médecine interne and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Sorbonne Universités, UPMC Univ Paris 06, F-75012, Paris, France. Electronic address: - - 2014
The use of the conventional APS treatment (the combination of low-dose aspirin and LMWH) dramatically improved the obstetrical prognosis in primary obstetrical APS (OAPS). The persistence of adverse pregnancy outcome raise the need to find other drugs to improve obstetrical outcome. Hydroxychloroquine is widely used in patients with various autoimmune ...
Riester Anna A A Riester, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, - - 2014
Primary aldosteronism (PA) is the most common cause of secondary hypertension. In this review we discuss the diagnosis and management of PA during pregnancy based on the literature. As aldosterone and renin are physiologically increased during pregnancy and confirmation tests are not recommended, the diagnosis of PA during pregnancy relies ...
Schuit E E Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, the Netherlands; Department of Obstetrics and Gynaecology, Academic Medical Centre Amsterdam, Amsterdam, the - - 2014
In twin pregnancies, the rates of adverse perinatal outcome and subsequent long-term morbidity are substantial, and mainly result from preterm birth (PTB). To assess the effectiveness of progestogen treatment in the prevention of neonatal morbidity or PTB in twin pregnancies using individual participant data meta-analysis (IPDMA). We searched international scientific ...
Pallivalappila Abdul Rouf AR Institute of Medical Sciences, The University of Aberdeen, Aberdeen AB24 3FX, - - 2014
To determine the prevalence and explore predictors of Complementary and Alternative Medicine (CAM) use during early pregnancy. A questionnaire survey of pregnant women (500) attending for mid trimester scan at the maternity services in Grampian, North-East Scotland. Outcome measures included; CAM used; vitamins and minerals used; independent predictors of use; ...
Guttuso Thomas T Jr Departments of Neurology and Obstetrics & Gynecology, University at Buffalo, 3435 Main Street, 97 Farber Hall, Buffalo, NY, USA. Electronic address: - - 2014
Restless legs syndrome (RLS) and nausea and vomiting of pregnancy (NVP) are both common maternal conditions affecting quality of life. Gabapentin is currently FDA-approved for treating RLS and preliminary results have shown it may be effective for treating the most severe form of NVP, hyperemesis gravidarum (HG). Because NVP and ...
Church Sarah S School of Health, The University of Northampton , Northampton , - - 2014
This paper seeks to explore midwives' experiences of pregnancy and childbirth. It draws on interviews with nine midwives who completed their midwifery training prior to becoming mothers, to discuss how midwives use their professional knowledge to exercise agency (the choices made about their own care), and assume autonomy (the control ...
Prins Jelmer R JR Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, PO Box 30001, Hanzeplein 1, 9700 RB Groningen, The Netherlands. Electronic address: - - 2014
Recurrent miscarriage is a reproductive disorder affecting many couples. Although several factors are associated with recurrent miscarriage, in more than 50% of the cases the cause is unknown. Maladaptation of the maternal immune system is associated with recurrent miscarriage and could explain part of its pathophysiology. Modulating the maternal immune ...
- - 2014
Postterm pregnancy refers to a pregnancy that has reached or extended beyond 42 0/7 weeks of gestation from the last menstrual period (LMP), whereas a late-term pregnancy is defined as one that has reached between 41 0/7 weeks and 41 6/7 weeks of gestation (). In 2011, the overall incidence ...
Oster Richard T RT University of Alberta, Edmonton, Alberta, Canada - - 2014
We conducted a focused ethnography with 12 First Nations women who had had diabetes in pregnancy to understand their real-life experiences and find ways to improve care for those with diabetes in pregnancy. We carried out unstructured interviews that were recorded, transcribed, and subject to qualitative content analysis. The experience ...
Rakhshani Abbas A a Department of Life Sciences , Svyasa University , Bengaluru , - - 2014
The prevalence of pregnancy complications are on the rise globally with sever consequences. According to the World Health Organization, every minute, at least one woman dies and twenty are affected by the complications related to pregnancy or childbirth. While the root cause of pregnancy complications is unclear, it likely has ...
Bryant Amy G AG Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC. Electronic address: - - 2014
Most states with 24-h waiting periods prior to abortion provide state resource directories to women seeking abortion. Our objective was to evaluate the information on abortion provided on the websites of crisis pregnancy centers listed in these resource directories. We performed a survey of the websites of crisis pregnancy centers ...
Phillips Jennifer - - 2014
To determine the completeness and readability of information found in Wikipedia for leading dietary supplements and assess the accuracy of this information with regard to safety (including use during pregnancy/lactation), contraindications, drug interactions, therapeutic uses, and dosing. Cross-sectional analysis of Wikipedia articles. The contents of Wikipedia articles for the 19 ...
Bacci Maria Laura ML Department of Veterinary Medical Sciences, DIMEVET, University of Bologna, Via Tolara di Sopra 50, Ozzano dell'Emilia, 40064 Bologna, Italy. Electronic address: - - 2014
Hair analysis has been proposed as a minimally invasive technique capable of furnishing information regarding the stress response during medium- and long-term periods. Bristle samples were collected from the rump region of sows at three key physiological phases (before delivery - BD; weaning time - WT; pregnancy diagnosis - PD) ...
Frawley Jane J 1 Australian Research Centre in Complementary and Integrative Medicine (ARCCIM), Faculty of Health, University of Technology Sydney , Ultimo, New South Wales, Australia - - 2014
Abstract Objectives: Up to 87% of women are using some form of complementary and alternative medicine (CAM) during their pregnancy, and this study was conducted to investigate the information sources that these women find influential in relation to such use. Design: The study sample was obtained via the Australian Longitudinal ...
Kavanagh Phillip S PS School of Psychology, Social Work and Social Policy, University of South Australia, Adelaide, South Australia, - - 2014
There are alarming rates of fetal alcohol spectrum disorder (FASD) in the Kimberley region of Western Australia despite numerous international studies demonstrating the links between alcohol consumption during pregnancy and FASD. The aim of this research was to help determine factors that may be associated with correct knowledge about safe ...
Lim Li Min LM Department of Obstetrics and Gynaecology, National University Hospital, NUHS Tower Block, Level 12, 1E Kent Ridge Road, Singapore 119228, - - 2014
Induced abortion is one of the most commonly performed gynaecological procedures in the world. Medical and surgical methods are available for both first- and second-trimester abortions. Generally, for women presenting between 7 and 14 weeks gestation, vacuum aspiration is an appropriate method. Medical method of abortion is otherwise recommended for ...
Cheong M A - - 2014
In the management of complex medical cases such as a multifetal pregnancy, knowledge of the ethical and legal implications is important, alongside having competent medical skills. This article reviews these principles and applies them to scenarios of multifetal pregnancy and fetal reduction. Such a discussion is not solely theoretical, but ...
Bertoldo Michael J MJ Unité de Physiologie de la Reproduction et des Comportements, Institut National de la Recherche Agronomique, Centre Val de Loire, UMR85, 37380 Nouzilly, - - 2014
Metformin is an oral anti-hyperglycemic drug that acts as an insulin sensitizer in the treatment of diabetes mellitus type 2. It has also been widely used in the treatment of polycystic ovary syndrome (PCOS) and gestational diabetes. This drug has been shown to activate a protein kinase called 5' AMP-activated ...
Broussard Cheryl S CS National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, - - 2014
To address information gaps that limit informed clinical decisions on medication use in pregnancy, the Centers for Disease Control and Prevention (CDC) solicited expert input on a draft prototype outlining a systematic approach to evaluating the quality and strength of existing evidence for associated risks. The draft prototype outlined a ...
Porteous Helen E HE Nutrition and Dietetics, Logan Hospital, Queensland Health, Meadowbrook, QLD 4131, - - 2014
A demonstrated link exists between maternal diet and maternal and infant health outcomes during and after pregnancy. A dietetic maternity service (0.6FTE for 3500 births) was introduced in 2012 at our hospital in a socially-disadvantaged area. We needed to develop evidence-based, patient-oriented improvements to nutrition services within resource limitations. This ...
Azizi Fereidoun F Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, - - 2014
Maternal hyperthyroidism in pregnancy is associated with adverse impacts on both mother and fetus. Recently, the American Thyroid Association and the Endocrine Society have published guidelines for the management of thyroid diseases in pregnancy. We aimed to disclose the impact of these guidelines in current practices of Asian members of ...
Theron Kathrine E KE School of Anatomical Sciences, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown 2193, South Africa; Department of Medical Sciences, Public Health and Health Promotion, School of Health Sciences, Faculty of Health Sciences, University of Limpopo, Private Bag X1106, Sovenga 0727, South Africa. Electronic address: - - 2014
RU486 is a partial progesterone and estrogen receptor antagonist, functioning to actively silence progesterone receptor gene-associated transcription. For this reason, it has been used as both a contraceptive and an abortive agent. In the present study, cellular and gene specific effects of RU486 were investigated in a rat model of ...
Cea Soriano Lucia L Spanish Centre for Pharmacoepidemiologic Research (CEIFE), Madrid, Spain; Department of Epidemiology, Harvard School of Public Health, Boston, MA, - - 2014
This study aimed to describe the management of antihypertensive medications in pregnancy by general practitioners in the UK and compare it with current guidelines. We used electronic medical records from The Health Improvement Network database from 1996 to 2010 to identify completed pregnancies. The study cohort included the first pregnancy ...
Stohl Hindi E HE UCLA David Geffen School of Medicine, Torrance, - - 2014
Shoulder dystocia is an unpredictable obstetric emergency with the potential for significant morbidity. Accurate and comprehensive documentation is critical for clinical decision-making and risk management. This study evaluates physicians' shoulder dystocia delivery notes to assess for comprehensiveness and identify potential areas for improvement. Physician narrative delivery notes for vaginal deliveries ...
Miller Lauren A LA Exempla Saint Joseph's Hospital & Tufts University School of Public Health, Denver, - - 2014
There are 57,000 opiate-exposed pregnancies every year in the United States. Buprenorphine is a promising therapy for opiate addiction during pregnancy, but there have been no investigations to date to determine the position of obstetricians regarding buprenorphine. This study surveyed obstetricians to assess their knowledge of buprenorphine and their current ...
Aftab Alam Haji Muhammad HM Department of General Medicine1 / Pulmonology2, Military Hospital, Mall Road, - - 2014
Snakebite in pregnant women is rarely reported in medical literature. It is almost non-existent to the best of our knowledge involving common krait (Bungarus caeruleus). The case reported here involved a 30 weeks pregnant young women from Rawalpindi (Pakistan), with myasthenia-like syndrome. The protocol employed in her treatment to cure ...
Kwon So-Young SY Department of Anesthesiology and Pain medicine, St.Vincent Hospital, Catholic University of Korea, Suwon, Republic of - - 2014
Pain is the most common complication of leiomyoma in pregnancy (1). Severe abdominal pain can occur if a leiomyoma undergoes degeneration, which occurs in 5-8% of leiomyomas during pregnancy (2, 3). We wish to call attention to successful severe pain management by epidural administration of a local anesthetic via a ...
Taheri M M 1Department of Obstetrics and Gynaecology, St Mary's - - 2014
Our national survey demonstrates increased use of medical and laparoscopic management of ectopic pregnancy in the UK. In the UK in 2000, 35% of cases were managed by laparoscopy, 63% by laparotomy and 1% with medication. A recent review in the USA revealed increasing rates of medical management and decreasing ...
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