Search Results
Results 401 - 450 of 1244
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Mayr A - - 2005
In this study we investigated whether the direct interaction between Candida albicans CBS 5982 and 5-hydroxytryptamine (5-HT) alters candidial virulence. Hyphae elongation, phospholipase activity and the production of secreted aspartyl proteinases (Saps) following 5-HT treatment were investigated. 5-HT treatment of C. albicans significantly (P < 0.05) affected hyphal extension, phospholipase ...
Kanade A N - - 2005
To develop an activity questionnaire for objective and rapid assessment of maternal habitual physical activity with the aim of describing its relationship with birth size. Prospective observational study. Six villages near Pune, Maharashtra, India. Seven hundred and ninety-seven rural Indian mothers were studied after excluding abortions and termination of pregnancies, ...
Chen Chia-Hsin - - 2005
OBJECTIVES: To assess the influence of ankle position on pelvic floor muscle (PFM) activity in women with stress urinary incontinence. METHODS: A total of 39 women, ranging in age from 38 to 72 years and clinically diagnosed with stress urinary incontinence, participated in testing of PFM activity changes during various ...
Poudevigne Melanie S - - 2005
PURPOSE: To compare three physical activity (PA) measures in pregnant women and examine mood correlates of physical activity changes during pregnancy. METHODS: A sample of 12 pregnant women (PW) was recruited during their first trimester and 12 nonpregnant women (NPW) (baseline age = 30.7 +/- 4.4 yr) were matched to ...
Moon Hyo-Eun - - 2005
Hypoxia-inducible factor 1 (HIF-1) is a master transcription factor that mediates cellular and systemic homeostatic responses to reduce O2 availability, such as erythropoiesis, angiogenesis, and glycolysis. Using the yeast two-hybrid screening system, we found that the oxygen dependent degradation (ODD) domain of HIF-1alpha interacts with necdin, a growth suppressor. The ...
Xin Hua-Wen - - 2005
OBJECTIVE: The present study was undertaken to investigate the possible effects of various agents on thiopurine methyltransferase (TPMT) activity in red blood cells (RBCs) from patients with chronic inflammatory bowel disease (IBD). METHODS: In three groups of patients with very high, normal and intermediate TPMT activity (each n=6), the inhibitory ...
Conforti Filomena - - 2005
This study reports on the biological properties, antioxidant and antidiabetic, of two varieties of Amaranthus caudatus seeds, Oscar blanco and Victor red. Oil, squalene and phenolic contents were also determined. Seeds of both investigated varieties were found to possess very different levels of squalene (2.2% in Oscar blanco variety and ...
Kranenbarg Sander - - 2005
Lordosis in fish is an abnormal ventral curvature of the vertebral column, accompanied by abnormal calcification of the afflicted vertebrae. Incidences of lordosis are a major problem in aquaculture and often correlate with increased swimming activity. To understand the biomechanical causes and consequences of lordosis, we mapped the morphological changes ...
Wojcicka J - - 2005
OBJECTIVES: Intrahepatic cholestasis of pregnancy (ICP) is associated with increased perinatal mortality and morbidity. Alpha-hydroxybutyrate dehydrogenase (alpha-HBDH) is an enzyme that originates in the cytoplasm of hepatocytes and can be detected in the serum. The aim of this study was to determine the characteristics of alpha-HBDH activity in ICP. METHODS: ...
Vermeulen Henricus M - - 2005
OBJECTIVE: To translate and adapt the original English version of the Shoulder Rating Questionnaire (SRQ) into the Dutch language (SRQ-DLV) and evaluate its internal consistency, reliability, validity and responsiveness to clinical changes. DESIGN: Prospective study. SETTING: Outpatient departments of orthopaedics, radiology and physical therapy of an academic and a non-academic ...
Clarke P E - - 2005
OBJECTIVE: Few studies provide data regarding the integrated everyday activities of Western pregnant women. The study aimed to quantify changes in the daily activity of women during pregnancy and to examine whether pregnancy has a differential impact on different activity domains. DESIGN: A prospective, longitudinal study of maternal time allocation ...
Bai Yu - - 2005
Biomass and microbial activity in backwashing processes of a biofilter for tertiary treatment were investigated. The microbial groups revealed new distribution along the biofilter depth after low flow rate backwashing for a short time. Then the start-up process was accelerated by backwashing. The biomass profile and microbial activity profile both ...
Uchikova Ekaterina H - - 2005
OBJECTIVES: (1) To study the changes in the haemostatic variables during normal pregnancy, and (2) to compare them with the corresponding variables in a control group of nonpregnant women. SETTING: University Hospital. SUBJECTS: The study involves two groups of women: pregnant women (in 35th-40th gestational weeks (GW)) (N = 35) ...
Pirazzoli Piero - - 2005
Ghrelin is a peptide with a potent capacity to release GH and other metabolic activities. An acyl modification is indispensable for biological activity. Acylated and desacylated forms of ghrelin are both present in the blood. No data exist about the ratio between active ghrelin and total ghrelin in the first ...
Kintraia Paliko I - - 2005
BACKGROUND: Very little is known about the perinatal genesis of circadian rhythmicity in the human fetus. Some researchers have found evidence of rhythmicity early on in fetal development, whereas others have observed a slow development of rhythmicity during several years after birth. METHOD: Rhythms of fetal heartbeat and locomotor activity ...
Nivsarkar Manish - - 2005
Many plants are known to possess antifertility activity. However, limited attempts have been made to scientifically evaluate these claims. Hibiscus rosa-sinensis flowers have been shown to possess antifertility and abortifacient activity. In this report, antiimplantation activity of water extract of leaves of H. rosa-sinensis was investigated. Pregnant female mice were ...
Hubatsch Ina - - 2005
The tripeptide amide glycyl-prolyl-glycinamide (GPG-amide) is a new antiretroviral drug candidate, but its absorption mechanism is unknown. In this investigation, the transport and metabolism of GPG-amide were studied in a model of the human intestinal epithelium, Caco-2 cell monolayers. The results show that when the tripeptide amide came into contact ...
Matthews Geoffrey M - - 2005
BACKGROUND: The purpose of the present paper was to assess the reproducibility of the (13)C-urea breath test ((13)C-UBT) and its ability to reflect the level of Helicobacter pylori-associated inflammation. METHODS: Asymptomatic H. pylori-positive subjects (n = 21) performed the (13)C-UBT six times. The H. pylori-positive symptomatic subjects (n = 55) ...
Tracy Timothy S - - 2005
OBJECTIVE: The purpose of this study was to determine whether drug metabolism (CYP1A2, CYP2D6 and CYP3A) activity varies in the pregnant state compared with the nonpregnant state. STUDY DESIGN: Subjects were studied at 14 to18 weeks of gestation, 24 to 28 weeks of gestation, and 36 to 40 weeks of ...
Zanata S M - - 2005
The participation of thiol-oxidoreductases such as thioredoxin during implantation, embryogenesis and fetal development has been extensively studied. Here, we analyzed the expression of the thioredoxin superfamily enzyme quiescin Q6/sulfhydryl oxidase (QSOX) during development. Results show that QSOX is present in fetal bovine serum (4 months' gestation), but its levels decrease ...
Venkateswarlu Kanamarlapudi - - 2005
IPCEF1 has been reported to interact with ADP-ribosylation factor GTP exchange factors of the cytohesin family and function by modulating the cytohesin 2 activity. This article describes methods used to study the interaction and activation of cytohesin GEFs by IPCEF1. The experimental approaches described here include physical and functional interaction ...
Malina Amanda A Magee-Womens Research Institute, Pittsburgh, PA 15213, - - 2005
System A amino acid transporter activity is reduced in placentas from small-for-gestational-age (SGA) compared to normal pregnancies. We compared the expression of the system A transporters between preeclamptic and control and between small-for-gestational-age and controls pregnancies. We used placental samples from 18 preeclamptic pregnancies matched with 17 normal pregnancies and ...
Gonzalez Eva M - - 2005
Endorepellin, the C-terminal domain of the heparan sulfate proteoglycan perlecan, possesses angiostatic activity. The terminal laminin-like globular (LG3) domain of endorepellin appears to possess most of the biological activity on endothelial cells. LG3 protein has been detected in the urine of patients with end-stage renal disease and in the amniotic ...
Lindseth Glenda - - 2004
This study was designed to examine the relationships of demographics, anthropometrics, prenatal physical activity, serum cholesterol, and nutrient intakes to symptomatic cholelithiasis (gallstone) occurrence in 128 northern plains pregnant women. Data collected at 14 and 26 weeks of pregnancy and 4 weeks after delivery, indicated 25.8% of the Native American ...
Sánchez-Luceros Analía - - 2004
ADAMTS13 dysfunction has been involved in the pathogenesis of Thrombotic Thrombocytopenic Purpura. This disorder occurs more frequently in women and, in 13% of them, is associated with pregnancy. However, there is little information on the protease behaviour in normal pregnancy. We studied von Willebrand factor and ADAMTS13 activity changes in ...
Al-Gubory Kaïs H - - 2004
The activities of copper, zinc-superoxide dismutase (SOD1), manganese SOD (SOD2), glutathione peroxidase (GPX), glutathione reductase (GSSG-R) and glutathione S-transferase (GST) were studied in sheep corpora lutea (CL) obtained on days 15, 40, 60, 80 and 128 of pregnancy. Maintained enzymatic activity of SOD1, SOD2, GPX, GSSG-R and GST were found ...
Shojaati Kushiar - - 2004
BACKGROUND: In normal pregnancy, an increased aldosterone (Aldo) concentration coincides with volume expansion. In preeclampsia, Aldo levels are low despite intravascular volume depletion. The present investigation aimed to characterize the compromised Aldo synthesis in preeclampsia, and to identify the molecular basis hereof. METHODS: We recruited 66 pregnant women (24 uneventful, ...
Waite Leslie L - - 2005
We previously described activators of peroxisome proliferator-activated receptor gamma (PPAR gamma) in the serum of pregnant women. We have also characterized this activating component by using a hexane-extracted serum fraction to examine PPAR activator levels in normal and preeclamptic (PE) pregnancies. In this study we report that the pregnancy PPAR ...
Yang Jun - - 2004
Epidemiological studies have indicated that the consumption of fruits and vegetables is associated with a reduced risk for the development of chronic diseases, such as cardiovascular disease and cancer. Phytochemicals, including phenolics and flavonoids, are suggested to be the major bioactive compounds contributing to the health benefits of fruits and ...
Skornicka Erin L - - 2004
A successful pregnancy can only occur when the maternal immune system fails to attack the allogeneic fetus. Two plasma proteins with described immunoregulatory activities, pregnancy zone protein (PZP) and placental protein-14 (PP14; also known as glycodelin-A), increase dramatically during pregnancy, prompting us to examine their potential role in mediating fetal ...
Keshri Govind - - 2004
Ethanolic extract of Ferula assafoetida and chloroform fraction of Melia azedarach, both devoid of estrogenic activity, were examined for their pregnancy interceptive property. Treatment of rats from days 1 to 7 of pregnancy with either of the plant extracts resulted in pregnancy failure in about 65-85% of the animals. The ...
Mousa Hatem A - - 2004
We investigated changes in both thrombin activatable fibrinolysis inhibitor (TAFI) antigen levels and its functional effect on in vitro fibrinolysis in normal pregnancy. 152 pregnant women and 31 women in the immediate postpartum period were studied, with pregnancy divided into 6 windows at 4 weekly intervals. As TAFI influences and ...
Moore Ayana - - 2004
Mitotic centromere-associated kinesin (MCAK) is a microtubule (MT)-destabilizing molecular motor. In the present study we show that the final 8 amino acids of the C-terminus of MCAK inhibit lattice-stimulated ATPase activity of the motor. Surprisingly, loss of this C-terminal 'tail' (MCAK-Q710) leads to more rapid depolymerization of MTs relative to ...
Chasan-Taber Lisa - - 2004
The effect of physical activity during pregnancy on maternal and fetal health remains controversial and studies have yet to identify the optimal dose of physical activity associated with favorable pregnancy outcomes. The aim of this study was to develop and validate a pregnancy physical activity questionnaire (PPAQ). To ascertain the ...
Rodríguez Ileana I - - 2004
As part of an ongoing program to explore the chemical constituents of Caribbean marine invertebrates, a family of 13 new diterpene glycosides, pseudopterosins P-Z (1-11) and seco-pseudopterosins H (12) and I (13), have been isolated from the organic extracts of two collections of the sea whip Pseudopterogorgia elisabethae procured near ...
Zhou Yiqiang - - 2005
Epoxyeicosatrienoic acids (EETs), which belong to cytochrome P-450 (CYP)-derived eicosanoids, have been implicated to vasodilate renal arterioles, inhibit sodium transport in the nephron, and regulate blood pressure in several animal models. Because pregnancy is associated with changes of blood pressure, the aim of this study was to examine whether renal ...
Lee Neung-Kee - - 2004
When hesperidin isolated from pericarpium of Citrus unshiu (family Rutaceae) was incubated with human intestinal microflora, its main metabolite was hesperetin, which was a main metabolite in urine of orally hesperidin-administered rats. The antiallergic activity of hesperidin and its metabolite hesperetin were investigated. Hesperidin did not inhibit the histamine release ...
Bergeron Kimberly G - - 2004
The main focus of this review is the management of active and latent tuberculosis in pregnancy in industrialized countries. The review is geared towards the healthcare professional taking care of the obstetric patient. The epidemiology of active and latent tuberculosis in the USA and recommendations for the screening of tuberculosis ...
DesMarais Vera - - 2004
Both the Arp2/3 complex and cofilin are believed to be important for the generation of protrusive force at the leading edge; however, their relative contributions have not been explored in vivo. Our results with living cells show that cofilin enters the leading edge immediately before the start of lamellipod extension, ...
Bujan-Nunez M C - - 2004
Brownian dynamics simulations were performed to determine the first collision and recollision rates of spherical reagent particles in a reaction medium made heterogeneous by the presence of randomly located inert spherical obstacles in a continuum solvent. The recollision rate vp (and hence the overall reactive collision rate when activation energy ...
Jenkin G - - 2004
In this review, our knowledge, gleaned from a range of species, of what determines gestation length, how fetal maturation and birth are synchronized and how the uterotonic mechanisms are activated at birth are discussed. Accumulated data indicate that fetal glucocorticoids are involved in, but do not necessarily play a causative ...
Gimenez Alejandro Piris - - 2004
There is a considerable body of evidence supporting the role of secretory type II-A phospholipase A(2) (sPLA(2)-IIA) as an effector of the innate immune response. This enzyme also exhibits bactericidal activity especially toward Gram-positive bacteria. In this study we examined the ability of sPLA(2)-IIA to kill Bacillus anthracis, the etiological ...
Fulford Jonathan - - 2004
Previous studies have demonstrated the practicality of using functional magnetic resonance imaging (fMRI) techniques to assess fetal brain activity. The purpose of this study was to compare the fetal hemodynamic response to that of the adult. Seventeen pregnant subjects, all of whom were at more than 36 weeks gestation were ...
Miyoshi M - - 2004
The objective of this study was to evaluate the distribution and phagocytotic function of macrophages in bovine caruncles during pregnancy. Pregnant Holstein caruncles obtained at a slaughterhouse and by Caesarean section just before the onset of parturition were used. Macrophages in these caruncles were observed immunohistochemically and histochemically. Macrophages were ...
Kellis Eleftherios - - 2004
PURPOSE: To examine knee joint kinematics, electromyographic (EMG) activity patterns and ground reaction forces (GRF) during an instep soccer kick from three different approaches relative to the ball. METHODS: Ten male soccer players performed maximum kicks from 0 rad (K0), 0.81 rad (K45), and 1.62 rad (K90) angle between the ...
Walther Thomas - - 2004
OBJECTIVES: To investigate the role of neutral endopeptidase in the turnover of atrial (ANP) and brain (BNP) natriuretic peptides and their N-terminal fragments in human fetal circulation. DESIGN: Retrospective case-control study. SETTING: Department of Obstetrics and Gynaecology, University of Leipzig, Germany. SAMPLE: Nine control pregnancies and nine pregnancies with rhesus ...
DenkbaĊŸ Emir B - - 2004
The aim of this study was the preparation and characterization of chitosan sponges including a model antibiotic (i.e., norfloxacin). The chitosan sponges were prepared by a solvent evaporation method. The matrix was also cross-linked during the preparation. The results indicated that the chitosan sponges were in the fibrillar structure. The ...
Gertsch Jürg - - 2004
The shrub Phyllanthus piscatorum Kunth (Euphorbiaceae) is cultivated by various ethnic groups of the Amazon because of its piscicidal properties. During ethnobotanical fieldwork among the Yanomamï Amerindians in Venezuela we observed that Phyllanthus piscatorum was exclusively cultivated and used by the women. Aerial parts of this herbaceous shrub are employed ...
Huisman M A MA Department of Obstetrics and Gynaecology, University Hospital Groningen, CMC V, 4th floor, Y4187, PO Box 30001 Hanzeplein 1, 9700 RB Groningen, The - - 2004
Trophoblast invasion is partly regulated by matrix-metalloproteinases (MMPs). Aberrations in MMP-activity in early pregnancy are thought to play a role in the pathophysiology of pregnancy associated conditions like pre-eclampsia and intra-uterine growth restriction (IUGR). A direct relation however, has not been published. We tested the hypothesis that MMP activity in ...
Pan Zhen-Qiang - - 2004
This review summarizes recent advances concerning the Nedd8 regulatory pathway in four areas. One, substantial progress has been made in delineating the role of cullin family proteins, the only known substrates of the Nedd8 modification system. Cullins are molecular scaffolds responsible for assembling the ROC1/Rbx1 RING-based E3 ubiquitin ligases, of ...
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