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Oppermann Marc M Institute for Clinical Teratology and Drug Risk Assessment in Pregnancy, Charité-Universitätsmedizin Berlin, 14050 Berlin, - - 2013
Angiotensin-II receptor 1 antagonists (AT₁-antagonists) may cause severe and even lethal fetopathy in late pregnancy. However, exposure still occurs in spite of warnings in package leaflets. This study aimed to assess the risk of fetopathy, the sensitive time window, and possible new symptoms in prospective as well as retrospective cases ...
Pouchieu Camille - - 2013
Information on dietary supplement (DS) use during pregnancy is largely lacking. Besides, little is known about the share of DS use as self-medication versus such use following a physician's advice/prescription. Our aim was to evaluate DS use and its socioeconomic, lifestyle and dietary correlates among pregnant women participating in the ...
Wall Kristin M KM Rwanda Zambia HIV Research Group, Department of Pathology & Laboratory Medicine, School of Medicine, Emory University, Atlanta, Georgia, United States of America ; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of - - 2013
We describe rates of unintended pregnancy among HIV positive couples in Lusaka, Zambia. We also identify factors associated with unintended pregnancy among oral contraceptive pill (OCP) using couples in this cohort. Data were analyzed from couples randomized in a factorial design to two family planning intervention videos. Rates of unintended ...
Köksal Ozlem O Department of Emergency Medicine, Faculty of Medicine, Uludag University, Bursa, - - 2013
This study aimed to determine the necessity of pregnancy test in women of reproductive age admitted to emergency department (ED) in routine practice. We retrospectively reviewed the records of patients who presented to the ED between January 1, 2006 and December 31, 2010 and received a pregnancy test. The median ...
Grillo-Mallo E - - 2012
A 38-year-old female, at 20-weeks gestation, experienced a sudden visual loss and visual-field abnormalities. The neuroimaging tests showed a craniopharyngioma. Surgical removal was performed with a successful outcome as regards the pregnancy and visual function. It is known that pituitary adenomas may grow during pregnancy; however this is unusual in ...
Brar Herb - - 2013
To determine the relationship between a priori risk for fetal trisomy and the fraction of fetal cell-free DNA (cfDNA) in maternal blood. A comparative analysis on fetal cfDNA amounts was performed in subjects stratified into a priori risk groups based on maternal age, prenatal screening results, or nuchal translucency measurement. ...
Reed Joanne H - - 2012
Maternal anti-Ro autoantibodies are associated with cardiac manifestations of neonatal lupus (cardiac NL), yet only 2% of women with this reactivity have an affected child. Identification of a more specific marker would channel intense monitoring to fetuses at greater risk. This study aimed to determine whether autoantibodies against Ro 52 ...
Gilead Rami - - 2012
Abstract OBJECTIVE: To investigate pregnancy outcomes, particularly cesarean delivery(CD), among women with "isolated" obesity (i.e. without additional co-morbidities). STUDY DESIGN: We conducted a retrospective population-based study between the years 1988-2010. The pregnancy outcomes of obese (pre-pregnancy BMI≥30 kg/m2) and non-obese patients were compared. Patients with chronic hypertension, pre-gestational diabetes mellitus, ...
Marchesi Dennis E - - 2012
As the use of assisted reproductive technologies (ART) continues to rise worldwide, it remains of the upmost importance to maintain the safety of those techniques used in ART. Many of these practices are unique to this discipline; as such, it becomes difficult to assess the true risks that the potential ...
Sánchez-Ferrer María Luisa - - 2012
We describe a rare case of complete hydatidiform mole with twin live fetus (CHMTF) confirmed by histopathology, flow cytometry, and polymerase chain reaction techniques. No malformations were observed, fetal karyotype was normal and β-human chorionic gonadotropin levels were increased (>100,000 IU/ml). Once the patient had been informed of the risks, ...
Koc Onder - - 2012
PURPOSE OF REVIEW: The article reviews the current evidence and the role of elective Cesarean section in the prevention of pelvic floor disorders (PFDs). RECENT FINDINGS: Recent studies have revealed that operative vaginal delivery is an important risk factor for PFDs. The cause of PFD is multifactorial. Pregnancy itself also ...
Tiitinen Aila - - 2012
The most important outcome of infertility treatment is a birth of a healthy baby. In many countries, in-vitro fertilisation treatments carry a high risk of twin pregnancy, which brings a higher risk to the mother and child than singleton pregnancies. Preterm delivery and low birth weight are the main factors ...
Lara Beatriz - - 2012
Three percent of rare diseases are pneumopathies. Improvements in survival and quality of life have led to a new situation where patients with rare respiratory diseases want to plan their reproductive lives. The intention of this review is to present the experience accumulated in the field of the reproductive health ...
Griffiths P D - - 2012
It is widely accepted that the diagnosis of foetal central nervous system (CNS) abnormalities can be improved by performing MRI examinations in utero. Most of the published literature has concentrated on pregnancies in which a developmental abnormality has been detected (or suspected) on ultrasound in an otherwise low-risk pregnancy. In ...
Gong Yun-Hui - - 2012
Early onset severe preeclampsia is a specific type of severe preeclampsia, which causes high morbidity and mortality of both mothers and fetus. This study aimed to investigate the clinical definition, features, treatment, outcome and risk factors of early onset severe preeclampsia in Chinese women. Four hundred and thirteen women with ...
Al-Kadri Hanan M F - - 2012
PURPOSE: We aimed in this research to explore factors contributing to the occurrence of intra-uterine fetal death (IUFD). METHODS: The study was conducted between 1st January 2008 and 31st December 2009 in the Department of Obstetrics and Gynecology at King Abdulaziz Medical City, Riyadh, Saudi Arabia. Patients who were diagnosed ...
Wain Karen - - 2012
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular dysplasia characterized by epistaxis, mucocutaneous telangiectasias, and arteriovenous malformations (AVM) in the brain, lung, liver, gastrointestinal tract, or spine. While pregnant women with HHT are known to have increased risks due to pulmonary AVMs, little is known about any increased risk ...
Wlodarczyk Bogdan J BJ Department of Nutritional Sciences, Dell Pediatric Research Institute, The University of Texas at Austin, Austin, Texas 78723, USA. - - 2012
The treatment of epilepsy in women of reproductive age remains a clinical challenge. While most women with epilepsy (WWE) require anticonvulsant drugs for adequate control of their seizures, the teratogenicity associated with some antiepileptic drugs (AEDs) is a risk that needs to be carefully addressed. Antiepileptic medications are also used ...
Yang Yun Seok - - 2012
Aim:  Risk assessment for cesarean delivery is not a one-time assessment, but rather a procedure that continues throughout pregnancy and labor. The objective of this study was to develop models to determine risk factors of cesarean delivery in three stages in low-risk pregnancy. Material and Methods:  The period from pregnancy ...
Dejesus Allison Sandra O - - 2012
ABSTRACT: Multiple gestations are high-risk compared with singleton pregnancies. Prematurity and intrauterine growth restrictions are the major sources of morbidity and mortality common to all twin gestations. Monochorionic twins are at a higher risk for twin-twin transfusion, fetal growth restriction, congenital anomalies, vasa previa, velamentous insertion of the umbilical cord ...
Vink Joy - - 2012
Twin gestations face an increased risk of structural abnormalities compared with singleton gestations, as well as an increased risk of aneuploidy. Accordingly, there is a need for accurate prenatal diagnosis of fetal genetic disorders and structural anomalies in twin gestations. Given the increased risk of congenital anomalies, a detailed sonographic ...
Rogenhofer Nina - - 2012
OBJECTIVE: To study the possible contribution of paternal, in addition to maternal, carriage of M2/ANXA5 as a risk factor for recurrent pregnancy loss (RPL). DESIGN: Case-control study. SETTING: Academic research center. PATIENT(S): Couples presenting themselves to the Fertility Center, Ludwig-Maximilians-University Munich with two or more consecutive, unexplained miscarriages were selected ...
Pandey Shilpi - - 2012
BACKGROUNDEarlier reviews have suggested that IVF/ICSI pregnancies are associated with higher risks. However, there have been recent advances in the way IVF/ICSI is done, leading to some controversy as to whether IVF/ICSI singletons are associated with higher perinatal risks. The objective of this systematic review was to provide an up-to-date ...
Watson Lyndsey F - - 2012
OBJECTIVE: to provide an accessible list of individual and population-based risk factors associated with very preterm birth to assist care providers in planning appropriate pregnancy care. DESIGN: a population-based case-control study. SETTING: Victoria, Australia. PARTICIPANTS: women were recruited from April 2002 to 2004. Cases had a singleton birth between 20 ...
Cohain Judy Slome - - 2012
The belief that hospital birth for low risk pregnancies has better outcomes than planned, attended homebirth is an urban legend. The choice of low-risk women to deliver in hospital is a result of the dominant and irrational human propensities to gossip, to follow the crowd and to cling to irrational ...
Bustamante-Aragonés Ana - - 2012
Prenatal diagnosis (PD) is available for pregnancies at risk of monogenic disorders. However, PD requires the use of invasive obstetric techniques for fetal-sample collection and therefore, involves a risk of fetal loss. Circulating fetal DNA in the maternal bloodstream is being used to perform non-invasive prenatal diagnosis (NIPD). NIPD is ...
Sen Sarbattama - - 2012
Obesity has reached near epidemic proportions in the developed world. As reproductive age women are a part of this trend, the effect of maternal obesity on the developing fetus must be investigated. In this review, we evaluated the experimental evidence relating maternal nutritional status and eating behavior before and during ...
Cassina Matteo - - 2012
Clinical hyperthyroidism has been associated with an increased risk of maternal, fetal, and neonatal complications. The available antithyroid drugs are methimazole/carbimazole and propylthiouracil. Several case reports and some epidemiologic studies suggest that methimazole/carbimazole exposure during the first trimester of pregnancy is associated with an increased risk of congenital malformations, including ...
Weissmann-Brenner Alina - - 2012
Objective. To compare maternal and neonatal outcomes of term large-for-gestational age (LGA) pregnancies and adequate-for-gestational age (AGA) pregnancies. Design. Retrospective analysis. Setting. Large university research medical center. Population. All term singleton LGA (birthweight ≥90(th) percentile) and AGA pregnancies (birthweight 10.1-89.9(th) percentile) delivering between 2004 and 2008. Methods. Data collected included ...
Chernick Lauren - - 2012
Emergency departments (EDs) care for adolescent females with unmet reproductive health care needs. Our objective was, among adolescents presenting to a pediatric ED, to estimate pregnancy risk, describe pregnancy intentions, and identify potentially modifiable factors associated with pregnancy risk. Using a paper-based questionnaire, we surveyed females aged 15-19 years presenting ...
Janssen Patricia A - - 2012
Commentary on: Birthplace in England Collaborative Group. Perinatal and maternal outcomes by planned place of birth for healthy women with low risk pregnancies: the Birthplace in England national prospective cohort study. BMJ 2011;343:d7400.
Azim M A - - 2012
The objectives of this study were to assess the sociodemographic profile and to identify the risk factors of ante-partum fetal death which occurs after the age of viability of fetus. This prospective observational study was conducted in the Obstetrics department of Ad-din Women Medical College Hospital during the period of ...
Hoffmann Elise - - 2012
Objective. To assess morbidity and mortality in twin pregnancy deliveries, according to chorionicity and mode of delivery. Design. Population-based retrospective cohort. Setting. Fourteen obstetric departments in Denmark. Population. One thousand one hundred and seventy-five twin pregnancies with two live fetuses at 36(+0) weeks of gestation. Methods. Pregnancy outcomes assessed according ...
Corrêa-Silva Eloisa P - - 2012
OBJECTIVE: To establish reference values for Doppler velocimetry of the ophthalmic artery (OA) and the central retinal artery (CRA) in low-risk pregnancy. METHOD: Between January 2008 and March 2009, 63 low-risk pregnant women underwent an ultrasound scan every 2weeks at the Women's Hospital, Campinas, Brazil, to determine the resistance index ...
Oyebode Femi - - 2012
INTRODUCTION: Perinatal psychiatric disorders are important because of their adverse effects on pregnancy outcomes. The aim of this review is investigate psychotropic drugs in the management of antenatal psychiatric disorders with emphasis on the risk of harmful effects. METHOD: A systematic review of published electronic literature between January 2000 and ...
Walsh Jennifer M - - 2012
Fetal macrosomia is associated with significant maternal and neonatal morbidity. In the long term, infants who are large for gestational age are more likely than other infants to be obese in childhood, adolescence and early adulthood, and are inherently at higher risk of cardiovascular and metabolic complications in adulthood. With ...
Brosens Ivo - - 2012
Bleeding from endometriotic implants is now an established cause of acute hemoperitoneum in pregnancy. However, the adverse impact of pelvic endometriosis on uterine function before conception may also interfere with subsequent deep placentation, accounting for the increased risk of obstetrical complications, including preterm birth and antepartum hemorrhage.
Hasegawa Junichi - - 2012
Placenta previa poses a high risk for massive hemorrhage, from the antenatal period until after Cesarean section. This condition increases the risk of maternal and neonatal mortality and morbidity. In cases of placenta previa, the prenatal prediction of sudden bleeding during pregnancy and blood loss during Cesarean section, and the ...
Chin Helen B - - 2012
Adolescent pregnancy, HIV, and other sexually transmitted infections (STIs) are major public health problems in the U.S. Implementing group-based interventions that address the sexual behavior of adolescents may reduce the incidence of pregnancy, HIV, and other STIs in this group. Methods for conducting systematic reviews from the Guide to Community ...
Valdiviezo Carolina - - 2012
More women than men die each year of cardiovascular disease, which remains the leading cause of death in the United States. Sex-specific factors, including pregnancy-related disorders, should be considered when assessing cardiovascular (CV) risk in women. Hypertensive disorders of pregnancy have been associated with CV risk later in life and ...
Koren Gideon - - 2012
Antidepressants are used commonly in pregnancy. Physicians who provide health care for pregnant women with depression must balance maternal well-being with potential fetal risks of these medications. Over the last decade, scores of original and review articles have discussed whether selective serotonin reuptake inhibitors-selective serotonin norepinephrine reuptake inhibitors possess risks ...
Torricelli Michela - - 2012
Abstract Preterm delivery and preeclampsia represent the main "obstetric syndromes", caused by multiple conditions, and characterized by complex pathogenesis. Nonetheless, recent evidences attest that deregulation of the immune system and exaggeration of inflammatory processes, taking place in the feto-placental unit, represent common central mechanisms occurring in both diseases. Tertiary prevention ...
Fraser Abigail A Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Oakfield House, Oakfield Grove, Bristol, United Kingdom. - - 2012
The nature and contribution of different pregnancy-related complications to future cardiovascular disease (CVD) and its risk factors and the mechanisms underlying these associations remain unclear. We studied associations of pregnancy diabetes mellitus, hypertensive disorders of pregnancy, preterm delivery, and size for gestational age with calculated 10-year CVD risk (based on ...
Hochner Hagit H Hebrew University-Hadassah, Braun School of Public Health, Jerusalem, Israel. - - 2012
Accumulating evidence demonstrates that both maternal prepregnancy body mass index (mppBMI) and gestational weight gain (GWG) are associated with adult offspring adiposity. However, whether these maternal attributes are related to other cardiometabolic risk factors in adulthood has not been comprehensively studied. We used a birth cohort of 1400 young adults ...
Jelliffe-Pawlowski Laura L - - 2012
Although maternal serum α-fetoprotein (AFP), human chorionic gonandotropin (hCG), and estriol play important roles in immunomodulation and immunoregulation during pregnancy, their relationship with the development of bronchopulmonary dysplasia (BPD) in young infants is unknown despite BPD being associated with pre- and postnatal inflammatory factors. We found that these serum biomarkers ...
Kiesewetter Barbara - - 2012
PURPOSE: To determine the efficacy and maternal complication rates of induction of labor, and to identify a concrete point in time for induction with the lowest possible risk for adverse events. METHODS: We designed a retrospective data analysis of all births at the general hospital of Vienna from 2003 to ...
- - 2012
Many pregnant women drink varying quantities of alcohol, although several guidelines recommend total abstinence. What is known of the dangers of alcohol for the outcome of pregnancy and for the unborn child? To answer this question, we conducted a review of the literature using the standard Prescrire methodology. Fetal alcohol ...
- - 2012
When there is a major risk of alcohol withdrawal symptoms in a pregnant woman, a 7-day course of benzodiazepine therapy has a positive harm-benefit balance. Medications designed to help maintain abstinence are not sufficiently effective to warrant initiating treatment during pregnancy.
Matlow Jeremy - - 2012
Some of my pregnant patients are afraid to take their antiepileptic drugs during pregnancy because of the known risk of malformations and the neurodevelopmental problems associated with valproic acid. Are there similar concerns with carbamazepine? Similar to valproic acid, carbamazepine increases the risk of neural tube defects; however, it does ...
Anderson Jane E - - 2012
This article reviews one of the less common but most dreaded complications of labor and delivery, shoulder dystocia, an infrequent but potentially devastating event that results from impaction of the fetal shoulders in the maternal pelvis. Shoulder dystocia occurs most commonly in patients without identified risk factors, and can result ...
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