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Results 251 - 300 of 1727
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Houtchens Maria K - - 2012
For women with multiple sclerosis (MS) who become pregnant, the risks and benefits of ongoing therapy for the health of both the mother and the fetus must be carefully considered. Based on a literature review and our MS center's standard practices, we provide guidance to aid clinical decision making in ...
Ramphul Meenakshi - - 2012
OBJECTIVE: To establish the current practice of obstetricians with regard to assessment of women in labour before instrumental delivery. STUDY DESIGN: A national postal survey of obstetricians in consultant-led obstetric units in the United Kingdom and Ireland. Clinical assessment before instrumental delivery, factors associated with difficulty in determining the fetal ...
Bayram Merih - - 2012
Abstract Objective: The objective of the study is to evaluate whether there is a difference in serum soluble free acid synthesis (sFas)/sFasL levels between patients with preeclampsia, severe preeclampsia and normal healthy pregnancy. Methods: This is a case control study comparing serum sFas and sFasL concentrations in patients with mild ...
Amash Alaa - - 2012
Preeclampsia is a pregnancy-specific disorder characterized by hypertension and systemic endothelial dysfunction. Interleukin (IL)-1β is a possible mediator of maternal endothelial dysfunction in preeclampsia. Serum IL-1β as well as its natural inhibitor IL-1 receptor antagonist (IL-1Ra) were reported to be increased in women with preeclampsia. In the current study, we ...
Bakalis Spyros P - - 2012
Abstract Objective: To examine the potential value of maternal serum level of C-reactive protein (CRP) in the first trimester of pregnancy in the prediction of spontaneous early preterm delivery. Methods: Maternal serum concentration of high-sensitivity CRP at 11-13 weeks' gestation was measured in a case-control study of singleton pregnancies delivering ...
Fenzl Vanja - - 2012
PURPOSE: Due to increased metabolic requests, pregnancy can be considered as metabolic stress, especially if associated with oxidative stress triggered by disbalance of pro/antioxidants. The aim of the study was to determine serum concentrations of the trace elements iron (Fe), zinc (Zn) and copper (Cu) important in growth regulation and ...
Ropacka-Lesiak Mariola - - 2012
Aim: The study evaluated the applicability of Doppler ultrasonography in predicting the course of pregnancy and neonatal outcome in dichorionic pregnancy complicated by growth discordance. Methods: Doppler examination of the umbilical artery (UA) and middle cerebral artery (MCA) was performed in 106 twins. Abnormal values of the UA pulsatility index ...
Bakhireva Ludmila N LN Department of Pharmacy Practice and Administrative Sciences, University of New Mexico Health Sciences Center, MSC09 5360, Albuquerque, NM 87131, USA. - - 2012
Carbohydrate-deficient transferrin (%CDT) is a well-established and highly specific biomarker for sustained heavy consumption of alcohol. However, in pregnant women, the specificity of this biomarker might be affected by advanced gestational age, even after accounting for increased transferrin concentrations in pregnancy. The goal of this prospective study was to assess ...
Hofmann-Kiefer Klaus F - - 2012
Severe inflammation has been shown to induce a shedding of the endothelial glycocalyx (EGX). Inflammatory cytokines, such as tumor necrosis factor α (TNF-α), impede the thickness of the EGX. While a controlled inflammatory reaction occurs already in normal pregnancy, women with hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome ...
Suri Vanita - - 2012
AIM: To study the role of fetal surveillance in intrahepatic cholestasis of pregnancy. MATERIALS AND METHODS: A total of 69 women with obstetric cholestasis were included. Fetal surveillance began at 34 weeks or later at diagnosis and included daily maternal record of fetal movements, biophysical profile (i.e., non-stress test, amniotic fluid ...
Monia Malek-Mellouli - - 2012
In order to evaluate the status of zinc and copper in pregnant women and in preeclampsia, we conducted a prospective case-control study. It involved 56 pregnant women compared with 30 non-pregnant women selected as controls. For pregnant women, serum levels of zinc, copper and ceruloplasmin were determined quarterly. These same ...
Hochman Eldar - - 2012
Pregnancy detection is a common procedure in primary care and can be challenging in the setting of military primary care clinics. The objective of this study was to determine whether the introduction of urine pregnancy tests to military primary care clinics is associated with earlier pregnancy detection. We conducted a ...
So Michelle - - 2012
Background Hypothyroidism is a common endocrine disorder that mainly affects women and the elderly. Objective This article outlines the aetiology, clinical features, investigation and management of hypothyroidism. Discussion In the Western world, hypothyroidism is most commonly caused by autoimmune chronic lymphocytic thyroiditis. The initial screening for suspected hypothyroidism is thyroid ...
Demir A - - 2012
The objective of this study was to find a possible correlation between Down syndrome and amniotic fluid leptin. We compared 2nd trimester amniotic fluid leptin levels of fetuses with normal karyotype and with trisomy 21. We retrospectively found 15 fetuses with Down syndrome and we randomly selected 48 fetuses with ...
Stevenson J S - - 2012
Our objectives were to determine characteristics (size, number, and stayability) of luteal structures formed in response to human chorionic gonadotropin (hCG) administered on d 7 after timed artificial insemination (AI) and the influence of hCG on returns to estrus and pregnancy outcome. Holstein cows (n=328), milked 3 times daily, previously ...
Kim M W - - 2012
The purpose of this study is to evaluate the relationship between maternal and/or cord blood folate/homocysteine concentrations and adverse pregnancy outcomes. The study population included a random sample of singleton pregnant women in whom we measured total homocysteine and folic acid in maternal or cord blood at deliveries. A total ...
Fiorini T - - 2012
Fiorini T, Susin C, da Rocha JM, Weidlich P, Vianna P, Moreira CHC, Bogo Chies JA, Rösing CK, Oppermann RV. Effect of nonsurgical periodontal therapy on serum and gingival crevicular fluid cytokine levels during pregnancy and postpartum. J Periodont Res 2012; doi: 10.1111/j.1600-0765.2012.01513.x.© 2012 John Wiley & Sons A/S Background ...
Kaitu'u-Lino Tu'uhevaha J - - 2012
A shift from type 1 to type 2 immune bias is essential for successful implantation and pregnancy. ST2 is a receptor present on type 2 immune cells and IL-33 was recently discovered to be its ligand. We measured serum levels of soluble ST2 (sST2) and IL-33 across the mid-first trimester ...
Loureiro Teresa - - 2012
Objective: To determine if in fetuses with aneuploidies the diameter of the fourth cerebral ventricle at 11-13 weeks' gestation is different from euploid fetuses. Methods: The fourth ventricle at 11-13 weeks' gestation was assessed in 62 cases of trisomy 21, 32 of trisomy 18, 10 of trisomy 13, and 12 ...
Barbato Olimpia - - 2012
The relationship between the concentration of plasma progesterone (P4) during embryo attachment or at recognition of pregnancy, and that of pregnancy-associated glycoprotein (PAG) was assessed in dairy cows. The outcome of artificial insemination (AI) was classified as positive (AI+), negative (AI-), or late embryonic mortality (EM) by measuring circulating PAG ...
Saito Felipe Hiroshi - - 2013
We evaluated associations between the concentrations of heat shock proteins (hsp60 and hsp70) and their respective antibodies, alterations in maternal reproductive performance, and fetal malformations in pregnant rats with hyperglycemia. Mild diabetes (MD) or severe diabetes (SD) was induced in Sprague-Dawley rats prior to mating; non-treated non-diabetic rats (ND) served ...
Feng Guixue - - 2012
Selective single-blastocyst transfer (SBT) in fresh cycles has been effective in reducing multiple pregnancies. However, we do not know whether this successful strategy of fresh transfer cycles is suitable for cryopreserved cycles. The present study was undertaken to evaluate the feasibility and value of SBT in vitrified-warmed cycles. Clinical pregnancy ...
Honnma Hiroyuki - - 2012
We used logistic regression analysis to investigate the relationship between serum anti-Mullerian hormone (AMH) levels and the rate of ongoing pregnancy. Retrospective data were collected from 1043 women who had undergone their first cycle of in vitro fertilization (IVF), including 540 cycles of fresh embryo transfer and 503 cycles of ...
Younis Abdelmoneim - - 2012
We investigated the activities and relevance of a validated panel of antioxidant enzymes, cytokines, specific lipid peroxidation end products and six fatty acids by correlational analyses with peak E(2) levels and pregnancy outcome after ovarian stimulation for IVF or IUI. Blood samples obtained from 15 patients undergoing ovarian stimulation with ...
Glynn Anders - - 2012
We investigated temporal trends of blood serum levels of 13 perfluorinated alkyl acids (PFAAs) and perfluorooctane sulfonamide (FOSA) in primiparous women (N=413) from Uppsala County, Sweden, sampled 3 weeks after delivery 1996-2010. Levels of the short-chain perfluorobutane sulfonate (PFBS) and perfluorohexane sulfonate (PFHxS) increased 11%/y and 8.3%/y, respectively, and levels ...
Tomimatsu Takuji - - 2012
During pregnancy, and especially during labor, the maternal carbon dioxide level declines considerably. Maternal carbon dioxide levels show a close relation with fetal carbon dioxide levels. The latter affects fetal cerebral oxygenation by regulating cerebral blood flow and shifting the oxyhemoglobin dissociation curve. In addition, maternal hypocapnia appears to impair ...
Eskild Anne - - 2012
OBJECTIVE: To study the association of maternal prepregnancy body mass index (BMI) with serum concentrations of hCG in early pregnancy. DESIGN: Cross-sectional study. SETTING: Oslo University Hospital, Norway, 1996-2010. PATIENT(S): Among 3,301 pregnancies with live-born offspring conceived after assisted reproductive techniques, 2,611 women had information on serum hCG concentrations on ...
McCarthy A - - 2012
Anti-NMDA-R encephalitis has been described as a cause of acute psychosis in young females. It is rare during pregnancy. We describe a primigravida 32-year-old woman with acute onset psychosis during the first trimester. Eight weeks after becoming pregnant, the patient became psychotic with associated catatonia and autonomic disturbance. Serum anti-NMDA-R ...
Akinlade F - - 2012
To investigate the levels of tumour markers CA 19-9 and CA 15-3 in the first trimester maternal serum of euploid control and trisomy 21 pregnancies. Maternal serum marker levels of 69 trisomy 21 and 388 euploid controls were quantified by the Kryptor analyser, and levels were compared between the two ...
Twina Guy - - 2012
Abstract Objective: Alpha-1 antitrypsin (AAT) is an anti-protease, anti-inflammatory and tissue-protective molecule. Normal circulating levels are <3.5 mg/dl and rise during pregnancy. Although AAT deficiency is associated with several pregnancy and placental disorders, little is known regarding AAT levels and preeclampsia. Since unopposed inflammation might contribute to preeclampsia, we studied ...
Siklósi György S - - 2012
PURPOSE: To re-evaluate the role of folliculo-luteal function (FLF) in recurrent miscarriage (RM) on the basis of new hormonal diagnostic criteria. METHODS: A prospective, randomized, single-blinded, placebo-controlled study was carried out at 110 apparently healthy patients with three or more miscarriages not related to any presumable predisposing factors of RM ...
Luo Zhong-Cheng - - 2012
It remains uncertain whether leptin and adiponectin levels are correlated in maternal versus fetal circulations. Little is known about whether leptin and adiponectin affect insulin sensitivity during fetal life. In a prospective singleton pregnancy cohort (n=248), we investigated leptin and adiponectin concentrations in maternal (at 24-28 weeks and 32-35 weeks ...
Clark Dinah M DM Division of Genetics, The Children's Hospital of Philadelphia, and Department of Pediatrics, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania 19104-4318, - - 2012
Cornelia de Lange Syndrome (CdLS) is a multisystem developmental disorder characterized by growth retardation, cognitive impairment, external and internal structural malformations, and characteristic facial features. Currently, there are no definitive prenatal screening measures that lead to the diagnosis of CdLS. In this study, documented prenatal findings in CdLS syndrome were ...
Hahn Sinuhe - - 2012
Introduction: Newly developed non-invasive prenatal diagnostic techniques, using maternal blood samples, have the potential to reduce or obviate the need for invasive prenatal diagnostic practices such as amniocentesis or chorionic villous sampling. This will lead to a change in how obstetric care is extended by health care providers to pregnant ...
Kachewar Sushil G - - 2012
PURPOSE: Fetal middle cerebral artery peak systolic velocity (MCA-PSV) is now an established method of noninvasive diagnosis of moderate to severe fetal anemia of different origins. This being a population-based parameter, it may have different values in individuals from different locations. A standard local reference range of normal individuals specific ...
Shapiro Bruce S - - 2012
The current study assessed the relationship between serum concentrations of human chorionic gonadotrophin (HCG) measured in the peri-implantation period and various outcome measures following blastocyst transfer in IVF cycles. The study group included 767 autologous IVF cycles, each with the transfer of two fresh blastocysts in a 6-year study period, ...
Ugur Mete Gurol - - 2012
PURPOSE: To compare total serum sialic acid (SA) levels between singleton pregnant women diagnosed with preterm labor between 24th and 36th weeks of pregnancy, singleton pregnant women at term, and their gestational age-matched controls. METHODS: Thirty pregnants diagnosed with preterm labor (group I), 30 gestational age-matched control pregnants (group II), ...
Findik Rahime Bedir - - 2012
PURPOSE: Gestational diabetes (GDM) is a metabolic disease characterized by the impairment of glucose tolerance during pregnancy. Sialic acid (SA) is a component of glycolipid and glycoproteins found in hormone and enzymes in serum and tissues and high serum SA levels are observed in diabetic patients. METHODS: Serum SA levels ...
Khalafallah Alhossain A - - 2012
BACKGROUND: To date there is minimal data available on D-Dimer levels at different stages of pregnancy. PATIENTS AND METHODS: We prospectively measured D-Dimer levels in 632 consecutive pregnant women from March 2007 to January 2009. The median age of the participants was 31years (range; 18-42) with a median weight of ...
Julania Shital - - 2012
A 31-year-old woman presented to the emergency department with sudden onset left upper quadrant pain radiating to the left shoulder. Urine β-hCG test was positive. Transvaginal sonography was suggestive of ruptured ectopic pregnancy with a large amount of free fluid in the pouch of Douglas. The patient was then taken ...
Baardman Maria E - - 2012
OBJECTIVE: Cholesterol is crucial for fetal development. To gain more insight into the origin of the fetal cholesterol pool in early human pregnancy, we determined cholesterol and its precursors in the amniotic fluid of uncomplicated, singleton human pregnancies. STUDY DESIGN: Total sterols were characterized by gas chromatography-mass spectrometry in the ...
Ball Susan - - 2012
Objective: Investigate gestational age dependent effects of racial origin, smoking status and mode of conception on maternal serum levels of free ß-human chorionic gonadotropin (β-hCG) and pregnancy associated plasma protein-A (PAPP-A) at 7-14 weeks' gestation. Methods: Data arise from prospective first-trimester combined screening for aneuploidies in singleton pregnancies, with serum ...
Sarunić Alenka Vukelić - - 2012
Pregnancy induced hypertension (PIH) is major contributor to maternal death in developing countries. Endothelin-1 (ET-1) is the most potent vasoconstriction agent known and its serum levels are increased in PIH. Therefore it is important to elucidate maternal and neonatal factors which influence endothelin-1 serum levels. 100 pathological pregnancies and 88 ...
Givens Vanessa M - - 2012
The declining death rate from ectopic pregnancy over the last 30 years has resulted not from improvements in operative technique, anesthesia, or blood banking but primarily due to more rapid diagnosis that allows for earlier treatment. Algorithms have been developed to eliminate delays in ordering the various diagnostic tests in ...
Hanita O - - 2012
Early pregnancy failure is a common pregnancy complication. In clinical practice, the time delay to distinguish viable from nonviable pregnancy is often distressing to patients and doctors. A highly sensitive and specific biomarker that accurately discriminates between viable and nonviable pregnancy would be useful for early intervention. Progesterone has been ...
Gervasi Maria-Teresa - - 2012
Intra-amniotic inflammation is traditionally defined as an elevation of amniotic fluid interleukin (IL)-6. Previous case control studies have suggested an association between an elevated midtrimester amniotic fluid IL-6 and preterm delivery, although such an association has been recently challenged. Intra-amniotic inflammation can also be defined by an elevation of the ...
Rausch Mary E ME Department of Obstetrics and Gynecology, Center for Human Reproduction, North Shore University Hospital, Manhasset, New York, USA. - - 2012
Unless an ectopic pregnancy is visible by ultrasound, diagnosis can be a challenge. Differentiating ectopic pregnancies from intrauterine pregnancies can be impossible without intervention or follow-up. This poses a clinical dilemma to the practitioner given the inherent danger to the mother of tubal rupture of an ectopic pregnancy versus the ...
Olausson Hanna H MRC Human Nutrition Research, The Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, - - 2012
Pregnancy and lactation are times of additional demand for Ca. Ca is transferred across the placenta for fetal skeletal mineralisation, and supplied to the mammary gland for secretion into breast milk. In theory, these additional maternal requirements could be met through mobilisation of Ca from the skeleton, increased intestinal Ca ...
Gu Hui - - 2012
The discovery of placental microRNAs (miRNAs) in maternal serum has opened up new possibilities for noninvasive prenatal diagnosis. However, the expression of miRNAs in the serum of pregnant women with fetuses with neural tube defects (NTDs) has not been characterized. In this paper, we explored serum miRNAs as potential biomarkers ...
Richardson A - - 2012
Abstract AIMS: The study was concerned with the medical management of ectopic pregnancy; specifically, (i) whether there is a significant increase in follow-up duration when the serum βhCG is greater than 3000iu/l and (ii) an association between the serum βhCG concentration at presentation and the need for a repeat dose ...
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