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Brezina Paul R PR Fertility Associates of Memphis, 80 Humphreys Center, Suite 307, Memphis, TN 38120, USA. Electronic address: - - 2014
There are few conditions in medicine associated with more heartache to patients than recurrent pregnancy loss (RPL). The management of early RPL is a formidable clinical challenge for physicians. Great strides have been made in characterizing the incidence and diversity of this heterogeneous disorder, and a definite cause of pregnancy ...
Godbole Koumudi - - 2013
Abstract Aim: To correlate and compare prenatal ultrasound with fetal autopsy examination to detect structural births defects and provide specific diagnoses. Methods: 141 second trimester fetuses (<20 weeks and <500 Gm) where pregnancy was terminated for structural birth defects and /or severe IUGR or intra-uterine death, referred to our tertiary ...
Saravelos Sotirios H SH Department of Obstetrics and Gynaecology, St Mary's Campus, Imperial College London, Mint Wing, South Wharf Road, London W2 1PG, - - 2014
Women with unexplained recurrent pregnancy loss (RPL) represent a highly heterogeneous group of patients. Past studies have investigated systemic endocrine and immunologic mechanisms as potential causes for pregnancy loss in unexplained RPL, while exciting new work has focused on spermatozoal, embryonic, and endometrial characteristics to explain the regulation of implantation ...
Hepner David L - - 2013
The prevalence of anaphylaxis occurring during pregnancy is approximately 3 cases per 100,000 deliveries. The management of anaphylaxis occurring during the third trimester of pregnancy may be challenging because of the additive effects of aortocaval compression and cardiovascular disturbances of anaphylaxis. In this review, we identify the clinical signs of ...
Cohen Stephanie E - - 2013
Syphilis is a complex, systemic disease caused by the spirochete Treponema pallidum. Syphilis is most commonly transmitted sexually or congenitally and can involve nearly every organ system. Its clinical progression involves several well-characterized stages: an incubation period, a primary stage, a secondary stage, a latent stage, and a late or ...
Bergman Hagit - - 2013
Some of my pregnant patients complain about pruritus. Are there conditions in pregnancy that present with pruritus that might put the mother or fetus at risk? Although most cases of pruritus can be attributed to itchy dry skin, there are conditions unique to pregnancy that involve pruritus as a leading ...
- - 2013
To the Editor: In their Perspective article, Morain et al. (Aug. 8 issue)(1) say that commercial companies have not met reasonable standards for demonstrating clinical validity. This is not correct. In five independent cohorts, researchers have examined 463 pregnancies with fetuses with Down's syndrome, 187 with trisomy 18, and 37 ...
Ashwood Edward R - - 2013
To the Editor: In their Perspective article, Morain et al. (Aug. 8 issue)(1) say that commercial companies have not met reasonable standards for demonstrating clinical validity. This is not correct. In five independent cohorts, researchers have examined 463 pregnancies with fetuses with Down's syndrome, 187 with trisomy 18, and 37 ...
Sehnert Amy J - - 2013
To the Editor: In their Perspective article, Morain et al. (Aug. 8 issue)(1) say that commercial companies have not met reasonable standards for demonstrating clinical validity. This is not correct. In five independent cohorts, researchers have examined 463 pregnancies with fetuses with Down's syndrome, 187 with trisomy 18, and 37 ...
Almashhrawi Ashraf A AA Ashraf A Almashhrawi, Khulood T Ahmed, Rubayat N Rahman, Ghassan M Hammoud, Jamal A Ibdah, Division of Gastroenterology and Hepatology, University of Missouri-Columbia, Columbia, MO 65212, United - - 2013
Pregnancy is a special clinical state with several normal physiological changes that influence body organs including the liver. Liver disease can cause significant morbidity and mortality in both pregnant women and their infants. Few challenges arise in reaching an accurate diagnosis in light of such physiological changes. Laboratory test results ...
Ahmed Khulood T KT Khulood T Ahmed, Ashraf A Almashhrawi, Rubayat N Rahman, Ghassan M Hammoud, Jamal A Ibdah, Division of Gastroenterology and Hepatology, University of Missouri-Columbia, Columbia, MO 65212, United - - 2013
Pregnancy is a special clinical state with several normal physiological changes that influence body organs including the liver. Liver disease can cause significant morbidity and mortality in both pregnant women and their infants. This review summarizes liver diseases that are unique to pregnancy. We discuss clinical conditions that are seen ...
Blumer Ian - - 2013
Objective: Our objective was to formulate a clinical practice guideline for the management of the pregnant woman with diabetes. Participants: The Task Force was composed of a chair, selected by the Clinical Guidelines Subcommittee of The Endocrine Society, 5 additional experts, a methodologist, and a medical writer. Evidence: This evidence-based ...
Rudra Samar S Department of Obstetrics and Gynecology, Maharishi Markendeshwar Institute of Medical Sciences and Research, Ambala, - - 2013
A broad ligament pregnancy is an extremely rare condition. Diagnosis is often missed and finally made during laparotomy. We present a case which remained undiagnosed throughout her pregnancy till she reached term and unfortunately had intrauterine foetal demise when she reported to our hospital. On clinical suspicion, ultrasound and magnetic ...
Kondo Rogerio Nabor RN State University of Londrina, Regional University Hospital of the North of Paraná, LondrinaPR, - - 2013
Impetigo herpetiformis is a rare dermatosis of pregnancy with typical onset during the last trimester of pregnancy and rapid resolution in the postpartum period. Clinically and histologically, it is consistent with pustular psoriasis. This similarity has led some authors to name the disease "the pustular psoriasis of pregnancy". We report ...
Greco Ermanno - - 2013
To evaluate the role of co-transfer of embryos derived from vitrified oocytes accumulated during the previous modified natural cycles and an embryo developed from the last one as an alternative to repetitive single embryo transfer ina fresh modified natural cycle. Thirty-six patients underwent ICSI procedure with three frozen natural oocytes ...
Galofré Juan Carlos - - 2013
Special considerations are warranted in management of thyroid nodule and thyroid cancer during pregnancy. The diagnostic and therapeutic approach of thyroid nodules follows the standard practice in non-pregnant women. On the other hand, differentiated thyroid cancer management during pregnancy poses a number of challenges for the mother and fetus. The ...
Boregowda Geethanjali - - 2013
This chapter on the gastrointestinal and hepatic systems in pregnancy focusses on those conditions that are frequent and troublesome (gastro-oesophageal reflux and constipation), distressing (hyperemesis gravidarum) or potentially fatal (obstetric cholestasis, acute fatty liver of pregnancy and HELLP (haemolysis, elevated liver enzymes, low platelets) syndrome). It also highlights the clinical ...
Ray Shona - - 2013
The use of antidepressant medications during pregnancy has stimulated much professional and public debate. As a consequence, considerable data on the reproductive safety of antidepressants has been generated that exceeds the available information for most, if not all, other classes of medications that may be used in the perinatal period. ...
Thompson Stephanie Marshall - - 2013
To determine which characteristics of blastocyst embryo morphology may predict clinical pregnancy and live birth rates. A retrospective analysis of data from 3,151 cycles of fresh, non-donor eSET cycles from 2008 to 2009 was performed. Data were obtained from the Society for Assisted Reproductive Technologies (SART) underwent. All eSET were performed ...
Koyama Shinsuke - - 2013
Anorectal symptoms and complaints caused by hemorrhoids or anal fissures are common during pregnancy. It is known that one-third of pregnant women complain of anal pain in the third trimester. Anal pain may be caused by a wide spectrum of conditions, but if it begins gradually and becomes excruciating within ...
Tannetta Dionne - - 2013
Preeclampsia remains a significant obstetric risk worldwide. The pathophysiology of preeclampsia is complex, with multiple stages involving maladaptations in both placental and maternal physiology. The placenta links the pre-clinical stage of impaired remodeling of the uterine vasculature, occurring in early pregnancy, to the later clinical stages characterised by the maternal ...
Kirk E - - 2013
BACKGROUNDA diagnosis of ectopic pregnancy (EP) is primarily achieved using transvaginal ultrasonography (TVS). Pregnancy of unknown location (PUL) is the term used to categorize a pregnancy in a woman with a positive pregnancy test when no pregnancy has been visualized using TVS. This review appraises current tools for the diagnosis ...
Sivabalan Somu - - 2013
Autoimmune polyendocrinopathy syndrome type 1 (APS-1) is characterized by the presence of at least two out of three clinical features, which include chronic mucocutaneous candidiasis (CMC), Addison's disease and hypoparathyroidism. The authors' present an one and a half year old girl with recurrent oral thrush who presented with generalised afebrile ...
Papafragkakis Haris - - 2013
Acute fatty liver of pregnancy is a rare but serious and potentially fatal complication of pregnancy. It typically presents in the third trimester with microvesicular fatty infiltration of the liver and can lead to multiorgan failure and death. Differentiation from hemolysis-elevated liver enzymes-low platelets syndrome can guide management. A high ...
Dashe Jodi S - - 2013
The diagnosis of placenta previa has shifted from clinical examination of the dilated cervix to sonographic assessment of the closed internal os, resulting in terminology confusion. If the cervix is closed, the distinction between a placental edge at the cervical margin and one partially covering the os is neither reliable ...
Abramowicz Jacques S - - 2013
Ultrasound is, arguably, the most commonly used diagnostic procedure in obstetrics. It is convenient, painless, yields immediate, extensive results, and is widely considered to be safe. Some (but not all) benefits described in the literature have been validated by evidence-based analysis, such as pregnancy dating. Others are considered clinically useful, ...
Sim Jae Eun JE Department of Neurology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, - - 2013
GNE myopathy is characterized by early-adult-onset distal myopathy sparing quadriceps caused by mutations in the GNE gene encoding UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, an enzyme in the sialic-acid synthesis pathway. A 27-year-old Korean woman presented a rapid deterioration in strength of the distal lower limbs during her first pregnancy. She was diagnosed ...
Emerson G G Human Assisted Reproduction Ireland, Rotunda Hospital, - - 2013
The first pregnancy after vitrification of a human blastocyst (day 5 of embryo culture) was reported by Yokota et al. in 2000. Since then more attention has been given to the technique of vitrification and its safe application in ART. To the best of our knowledge, this is the first ...
Sorbi Flavia F Department of Science for Woman and Child Health, University of Florence, Florence, - - 2013
Primary choriocarcinoma of the uterine cervix is an extremely rare disease. The clinical diagnosis of cervical choriocarcinoma is difficult, because of its rarity and being non-specific abnormal vaginal bleeding the most common symptom. In the present report, the authors present a case of cervical choriocarcinoma, which was initially misdiagnosed as ...
Unnikrishnan Ambika Gopalakrishnan AG Department of Endocrinology and Diabetes, Chellaram Diabetes Institute, Pune, - - 2013
It is well known that thyroid disorders commonly affect women. The care of pregnant women affected by thyroid disease is an important clinical challenge for endocrinologists. Hypothyroidism is the commonest problem, and maternal hypothyroxinemia has been linked to adverse feto-maternal outcomes. This article would discuss the controversy regarding first-trimester thyroid ...
Aflatoonian Nastaran N Madar Hospital, Yazd, - - 2013
Cryopreservation of embryos has been an usual component of clinic in assisted reproductive technology (ART) programs. Recently the dramatic increase in cryobiology activity in the clinical centers has enhanced methods of freezing and improved vitrification protocols are being developed. The aim of our study was to assess the effect of ...
Torabizadeh Aalie A Department of Obstetrics and Gynecology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, - - 2013
Ovarian hyperstimulation syndrome (OHSS) is the most serious and potentially life-threatening iatrogenic complication associated with ovarian stimulation during Assisted Reproductive Technology (ART) protocols. OHSS typically is a result of ovarian expression of vascular endothelial growth factor (VEGF) which increases vascular permeability. Comparison of albumin and cabergoline in the prevention of ...
Capone Fioravante - - 2013
Low back pain (LBP) is a very common complaint in pregnancy. For this reason, it is often considered directly attributable to the pregnancy rather than a medical problem requiring diagnostic workup. Pregnancy-related LBP should be differentiated from the rare cases of LBP associated with serious spinal diseases. Hemangioblastoma is a ...
Hadar Eran - - 2013
The various strategies to diagnose gestational diabetes mellitus (GDM), starting from O'sullivan, followed by numerous opinions and recommendations and up to the recently published International association of diabetes and pregnancy study groups criteria, have been and still are the subject of extensive and ongoing debate, since the 1960s, and holding, ...
Evbuomwan Isaac - - 2013
Abstract Severe Ovarian Hyperstimulation Syndrome (OHSS), with an incidence of 1-2% of superovulation cycles, remains one of the most important complications of gonadotrophin use in assisted reproductive technologies because of its associated morbidity and rarely, mortality. Despite the wealth of scientific and clinical interest that this iatrogenic complication has generated, ...
Vidaković Snezana S Clinic for Gynaecology and Obstetrics, Clinical Center of Serbia, Belgrade, - - 2013
Transvaginal sonography and human chorionic gonadotropin (hCG) testing are cornerstones of modern clinical practice in cases with the suspected ectopic pregnancy. In unclear cases, if the level of hCG is above the discriminatory zones, the use of uterine curettage is recommended.There is an increasing concern that strict observation of the ...
Ottonello Giovanni G Neonatal Intensive Care Unit, Puericulture Institute and Neonatal Section, University of Cagliari, - - 2013
An eleven-day boy neonate with a fetal anamnesis of grade 1 bilateral hydronephrosis according to the grading of the Society for Fetal Urology (SFU), came to our attention for an acute osteoarthritis secondary to urosepsis. In the urological follow-up, a severe bilateral vesico-ureteral reflux (VUR) was diagnosed. An early post-natal, ...
Bouzguenda Racem - - 2013
Multiple myeloma (MM) is a systemic disease in the elderly. Its incidence in patients younger than 40 years old and especially in pregnant women is extremely rare. MM may involve extraosseous sites, and only in rare cases it is observed in the breast. We describe the case of a 39-year-old woman ...
Prochnau Dirk D Department of Internal Medicine I, Jena University Hospital, Erlanger Allee 101, 07747, Jena, Germany. - - 2013
The role of hormonal changes during pregnancy in Brugada syndrome is unknown. Only rare case reports of Brugada syndrome during pregnancy have been published. In this article, we describe a patient with first clinical manifestation of Brugada syndrome during pregnancy. The definitive diagnosis could only be achieved by drug challenge ...
Dain Lena - - 2013
To evaluate the combined effect of endometrial thickness and anatomic uterine factors on clinical outcome in oocyte donation recipients. Retrospective analysis of oocyte donation cycles conducted between 2005 and 2010. Two private IVF centers. A total of 737 donor oocyte cycles. None. Clinical pregnancy and live birth rates. No statistically significant ...
James Daphne J - - 2013
The ionizing radiation used in diagnostic nuclear medicine procedures has the potential to cause biologic harm to a fetus. Although the risks are relatively small, it is recommended that all female patients of childbearing age be questioned regarding their pregnancy status before administration of the radiopharmaceutical. This can be a ...
Aydin Yunus - - 2013
To compare the clinical pregnancy rates between intrauterine insemination (IUI) simultaneously or 34-36h following hCG injection in gonadotropin-stimulated IUI cycles. Randomized, prospective, controlled, study conducted in a university infertility clinic. Of 923 infertile couples, 220 couples with unexplained infertility or mild male factor infertility were included to the study. Before ...
Nankervis Alison - - 2013
Recommendations to change the diagnostic criteria for gestational diabetes mellitus (GDM) are controversial. Two sets of criteria are currently in use in Australia, which has led to considerable confusion. This article discusses the rationale behind the proposed changes to the diagnostic criteria, and aims to clarify the current approach to ...
Valayatham V - - 2013
Analyze indications and type of prenatal diagnostic procedures performed. Method: This retrospective audit was conducted at a dedicated fetal medicine center in Petaling Jaya. All invasive prenatal diagnosis procedures performed from 2003 up until 2010 (amniocentesis, chorionic villous sampling and fetal blood sampling) were analyzed. A total of 1560 invasive ...
Suciu N - - 2013
Abstract Fetal tumors are rare and can be difficult to diagnose in utero. In this presentation, we report an infantile hemangiopericytoma of the tongue, and also review the clinical characteristics, imaging appearances, perinatal differential diagnosis, and potential treatments of this tumors. Prenatal diagnosis of lingual fetal tumors with two-dimensional (2D) ...
Reynolds Kasey A KA Department of Obstetrics and Gynecology, Washington University School of Medicine, 4444 Forest Park Ave., Ste. 3100, St Louis, MO 63108, - - 2013
Does a luteal estradiol (LE) stimulation protocol improve outcomes in poor responders to IVF? LE priming is associated with decreased cycle cancellation and increased chance of clinical pregnancy in poor responders Poor responders to IVF are one of the most challenging patient populations to treat. Many standard protocols currently exist ...
Ramirez J O - - 2013
Restless legs syndrome (RLS) is a common neurologic disorder. Secondary RLS includes pregnancy and iron deficiency. Prevalence of RLS in pregnancy ranges from 11% to 27%. We aimed to assess the frequency and characteristics of RLS in pregnancy in a Peruvian population and to evaluate the possible pregnancy or delivery ...
Virkus Rie Adser - - 2013
The aim of this study was to describe venous thromboembolism (VTE) in pregnancy and the puerperal period and to validate diagnoses of VTE. Historical cohort study. All pregnancies in Denmark from 1995 to 2009. VTE diagnoses were retrieved from national registries. Positive predictive value of a VTE diagnoses diagnosed during ...
Erman Akar Munire - - 2013
To present the first clinical pregnancy after uterus transplantation. Case study. Tertiary center. A 23-year-old Mayer-Rokitansky-Kuster-Hauser syndrome patient with previous vaginal reconstruction and uterus transplantation. Eighteen months after the transplant, the endometrium was prepared for transfer of the thawed embryos. Implantation of embryo in an allografted human uterus. The first ...
Bellver José - - 2013
To analyze the reproductive outcome of recipients of donated ova according to their body mass index (BMI). Twelve-year retrospective cohort analysis. Fertility clinics. 9,587 first cycles of ovum donation with ova from normoweight donors. Recipients divided according to their BMI to analyze IVF laboratory and outcome parameters: lean with BMI ...
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