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Results 351 - 400 of 484
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Wilcox L R - - 1991
This study used a special jig system, photography, and a sonic digitizer to evaluate the change in canal size and location after retreatment in 20 teeth with small or large curved canals (greater than 23 degrees). During initial instrumentation, small canals enlarged twice as much as large canals in the ...
Manabe Y - - 1991
We studied the tensile strength and collagen content of the amniotic membrane in the early and late second trimester and at term in specimens obtained after spontaneous, cesarean, and prostaglandin- and stretch-induced deliveries. No significant difference in either tensile strength or collagen content was found among any group of samples. ...
Ubelaker D H - - 1991
Occasionally, partial calvariae of hydrocephalic calves are found in forensic contexts and mistakenly identified as human. Such specimens can be properly identified through immunological assessment of associated soft tissue, microscopic analysis of associated hair, and morphological comparison with documented museum specimens. Morphological comparison should focus on the form of the ...
Kaidi R - - 1991
Post-partum involution of the bovine uterus was assessed by clinical examination and monitored biochemically by measuring the total urinary excretion of hydroxyproline and the collagen cross-link, pyridinoline. Uterine tissue contained 0.13 +/- 0.04 residues of pyridinoline per mole of collagen and negligible (less than 0.005 residues/mole) deoxypyridinoline. The pyridinoline/creatinine ratio ...
Mast B A - - 1991
The extracellular matrix (ECM) of fetal rabbit wounds contains an abundance of the glycosaminoglycan hyaluronic acid (HA) but is devoid of excessive collagen. Thus, fetal wounds heal without scarring, such that tissue repair grossly resembles regeneration. To obtain further insight into the process of fetal wound healing, the ECM of ...
Evanko S P - - 1990
Clear distinctions in morphology and proteoglycan composition have been described in regions of adult tendon that pass under bone and are subjected to compressive as well as tensional forces. In this study, developing bovine deep flexor tendon from early fetal stages through 6 months of age was examined biochemically and ...
Stern S J - - 1990
To study the vascular effects of a new photosensitizing agent independent of the influence of tumor growth, a cutaneous wound model was used. Six-week-old Harlan-Sprague-Dawley "Fuzzy" rats were surgically wounded in a standard fashion. The animals were then divided into three groups: the first group received chloroaluminum-sulfonated phthalocyanine only, the ...
Gruber H E - - 1990
The short rib polydactyly syndromes (SRP) are lethal neonatal skeletal dysplasias with a narrow chest, short limbs, and other abnormalities. Type II (Majewski) short rib polydactyly can be distinguished from the Type I/III (Saldino-Noonan) type on the basis of radiographic and histologic changes. Our previous transmission electron microscopic studies suggested ...
Burd D A - - 1990
Foetal wound healing occurs without scarring. A scar is a collagen-rich repair tissue, and the absence of scarring in the foetus has raised questions concerning the presence and nature of collagen deposition in foetal wounds. Studies of collagen deposition in foetal wounds in small animals, performed late in gestation, have ...
Burd D A - - 1990
The ability of fetal skin wounds to heal without scar formation is remarkable. The mechanisms that endow the fetus with this unique healing ability remain unknown. We have developed an in vitro explant model using fetal sheep skin to investigate fetal wound healing. This model eliminates the complex systemic mechanisms ...
Sharpe K L - - 1990
The proportions of Type I and Type III collagen were evaluated from gestational, postpartum-retained, and released bovine placental membranes. Placentomes were excised at 90, 150, 210, and 270 days of gestation (n = 32) and from postpartum-retained (2 and 12 h, n = 8) and released (2 h, n = ...
Longaker M T - - 1990
Recent clinical and experimental data indicate that fetal wound healing occurs without the accompanying inflammation and scar formation typical of postnatal wounds. The lack of scar tissue may have significant implications for craniomaxillofacial surgery. This report documents the development of a model for fetal cleft lip repair in rabbits. The ...
Wood V E - - 1990
Congenital fossae, skin pits, or dimples can form about the shoulder. Little has been written about congenital supraspinous fossae or dimples. They are thought to result from the catching of tissues between a sharp bony post and the uterine wall. The skin and structures become compressed and adherent, and when ...
Cintron C - - 1990
We used a staining procedure specific for sulfated glycosaminoglycans, cuprolinic blue dye (CBD), and immunohistochemical techniques to determine the histological distribution and ultrastructural organization of proteoglycans in developing rabbit cornea. We found several types of CBD-stained structures located throughout the corneal stroma, indicative of the distribution and perhaps the chemical ...
Nuñez L - - 1990
A counterimmunoelectrophoretic (CIE) technique was developed to detect botulinic toxin type A, and the method was compared with the mouse bioassay. A 100 LD50 concentration was detected within 2 h. Crossed reactions were observed with antitoxins of types B and F. As regards other Clostridium species, precipitin lines were seen ...
Hinderer U T - - 1990
The early reaction to the injection of silicone, collagen, and lyophilized heterologous fetal connective and cartilage tissues into the limiting zone deep dermis-superficial subcutaneous tissue was histologically examined in the pig and compared with clinical results. The inflammatory reaction to lyophilized heterologous fetal tissue is considerably more intense than that ...
Xu D Q - - 1990
The distribution of collagen type IV and VI, laminin and nidogen was investigated by immunofluorescence microscopy in the livers of marmosets (Callithrix jacchus) at various stages of development, i.e. on days 93, 111, 116 and 134 of gestation, 1 day postpartum and at the mature stage. Large amounts of collagen ...
Vadillo-Ortega F - - 1990
Collagen content, acid-soluble collagen, degradation activity, and collagen biosynthesis were measured in 22 normal and 20 prematurely ruptured membranes from pregnancies near term (37 weeks or more). Although no significant differences were found in the collagen content, a clear correlation was found between this value and the interval from premature ...
Myers D B - - 1990
Collagen concentrations at implantation sites in the rat uterus were found to be significantly decreased compared with concentrations in adjacent non-involved uterine tissue in early pregnancy (75% by Day 11). The decrease in collagen was most marked in primary decidua and was also observed to a lesser extent (20%) in ...
Yoshida Y - - 1990
The occurrence of dissociation in cervical collagenous tissue during pregnancy and delivery is widely recognized. We performed a morphologic study of the collagenous tissue of the amnion at various stages of pregnancy and during delivery. After 15 weeks of pregnancy, including the period after delivery, the collagenous fibers of the ...
Rukosuev V S - - 1990
The indirect immunofluorescence method was used to study the human term placenta in pathological pregnancy for the distribution of collagen types I, III, IV, V, and fibronectin in fibrosis stromatis villi. All collagen types and fibronectin were shown to participate in fibrosis villorum formation. Fibronectin was also detected in the ...
Longaker M T - - 1990
The mechanisms that underlie the lack of scarring in fetal wounds are unknown, but probably relate to the control of collagen fibrillogenesis. The role of collagen in the fetal wound matrix is controversial, and several wound implant models have been used to evaluate collagen deposition in fetal wounds. Unfortunately, these ...
Offringa P J - - 1989
Abdominal pregnancy is rare; conjoined twins are also rare. The diagnosis of abdominal pregnancy is easily missed and often not made until near full-term. Similarly conjoined twins are not diagnosed until late in gestation or during parturition. In this case, the diagnosis of conjoined twins and abdominal pregnancy was only ...
Petrikovsky B M - - 1989
The sonographic characteristics and the frequency of the presence or absence of fetal hair in the occipital region was determined from 16 weeks to 42 weeks of menstrual age. Our results suggest that the ultrasonic appearance of occipital hair is first noted at approximately 24 weeks of menstrual age and ...
Williams R O - - 1989
In order to discover whether changes in the nature of the humoral response to type II collagen occur during pregnancy we compared, by enzyme-linked immunosorbent assay (ELISA), the anti-type II collagen antibody titres and isotype profiles of pregnant and virgin DBA/1 mice immunized with type II collagen. Significant reductions in ...
DePalma R L - - 1989
Fetal response to injury has been characterized by the deposition of a matrix that is not primarily collagen. This study was designed to identify this matrix, in order to better understand the fetal mechanism of tissue repair. Silastic/polyvinyl alcohol sponge (PVA) wound implants were placed paravertebrally in 24-day gestation (31 ...
Chung J H - - 1989
The effect of topically applied 1% and 2% sodium hyaluronate was studied on the healing of a standardized rabbit corneal alkali wound. The healing of the epithelium, the stroma, and the endothelium was evaluated separately by applying quantitative methods. The healing was followed for 8 weeks. Both 1% and 2% ...
Halaburt J T - - 1989
Fetal membranes obtained from second-trimester abortions, elective Caesarean sections and after normal deliveries were studied. The hydrolytic activity against a DNP-peptide expressing the collagen turn-over was found to be very high in the second trimester and relatively high at term of pregnancy. The activity in the chorion was twice that ...
Murray L W - - 1989
A description of an abnormal segment-long-spacing crystallite (SLS) pattern has been reported for type II collagen from patients with diastrophic dysplasia (Stanescu et al., 1982 a), a disorder that is characterized by large collagen fibrils in the cartilage matrix. The abnormal SLS consisted of an altered electron density between bands ...
Okumura Y - - 1989
In order to elucidate the phenomenon of vibrations of the mandible, a simplified plaster model was prepared and the fundamental vibrations were investigated. Studies using either dried human skulls or in situ mandible yielded similar results. The results obtained were as follows: 1. The vibrations generated by tapping a simplified ...
Antonelli D - - 1989
Female conjoined twins were delivered after 42 weeks' gestation, but they died within a few minutes of birth. They were dicephalus, dibrachius and dipus conjoined twins with two separate spines and fusion of the trunk and the pelvis. The pericardial sac was common, and the heart was a single structure. ...
Seegmiller R E - - 1988
The severe lethal chondrodystrophies in man result in a common clinical syndrome including shortening of the face, mandible, and limbs. Studies of three lethal chondrodystrophic mutants in mice, viz., chondrodysplasia (cho), cartilage matrix deficiency (cmd), and disproportionate micromelia (Dmm), which share this syndrome, were performed with the aim of identifying ...
Trépanier H - - 1988
Serial undecalcified cross sections were examined in order to establish the distribution of calcified cartilage, woven and lamellar bones in the nasal ventral conchae of piglets aged between birth and six weeks. The distribution of the mineralized tissues varied according to the age of the piglets and to the level ...
Hallock G G - - 1988
The absence of apparent scar formation following the creation of surgical wounds in utero appears to be a phenomenon peculiarly privileged as a sequela of fetal wound healing. Little information exists to explain this disparity from our knowledge of adult wound healing. Therefore, following creation of surgical wounds in fetal ...
Hultcrantz M - - 1988
Pregnant CBA/CBA mice were exposed to 0.5, 1 and 2 Grey (Gy), (1 Gy = 100 rad) in single doses with whole body gamma-irradiation on the 12th, 13th and 16th gestational days, respectively. The animals were tested at an age of one month for vestibular and cochlear function. Thereafter the ...
Arnoczky S P - - 1988
To evaluate the ability of a fibrin clot to stimulate and support a reparative response in the avascular portion of the meniscus, two-millimeter-diameter full-thickness lesions in the avascular portion of the medial meniscus of twelve adult dogs were filled with an exogenous fibrin clot that had been prepared from each ...
Aplin J D - - 1988
Changes in the organisation and composition of extracellular matrix in human endometrium during the menstrual cycle and early pregnancy have been assessed by immunofluorescence. Amongst interstitial components, type-III and type V-collagens and fibronectin are present in endometrial stroma throughout the menstrual cycle as well as in first trimester decidua. Type ...
Olerud J E - - 1988
The purpose of this study was to document a timetable for selected events of epidermal repair in standard partial thickness incised wounds on the legs of normal elderly human subjects. A Simplate-II bleeding-time device was used for producing the wounds, and immunohistochemical techniques were employed for evaluation of the wounds. ...
Tisdale A S - - 1988
The sequence of development of the components of the corneal adhesion complex (hemidesmosomes, basal lamina and anchoring fibrils) was studied in rabbit and human fetal corneas using electron microscopy and histochemical localization of type VII (anchoring fibril) collagen. In the rabbit, basal lamina was present at 15 days gestation, followed ...
Muzzarelli R - - 1988
Reparative processes are reconstructive phenomena in which cellular elements and extracellular matrix glycoproteins interact to build the injured tissue. Biomaterials can be used to improve or stimulate reconstruction. In the present experimental investigation, tissue repair induced by chitosan, an 86.8% deacetylated poly(GlcNAc), was monitored by morphological analysis. To evaluate its ...
Morris J E - - 1988
Heparan sulfate proteoglycans (HSPGs) and dermatan sulfate/chondroitin sulfate proteoglycans may be extracted from the uterine epithelium of immature mice by a 1-min exposure of the luminal surface of excised uteri to 1% Nonidet P-40 detergent. In mice that are treated with estradiol there is a marked increase in free heparan ...
Salisbury J R - - 1988
Intervertebral discs, formed from notochord cell expansions during embryogenesis, are known to contain proteoglycans bearing keratan sulphate chains. Keratan sulphate has previously been demonstrated in Xenopus and chick notochords and in human fetal cartilage. In contrast, we have been unable to demonstrate keratan sulphate in human fetal notochord using two ...
Aspden R M - - 1988
A theory is presented that relates changes in the mechanical properties of the uterine cervix during pregnancy and the puerperium to changes in biochemical composition. The cervical connective tissue is considered as a fibre-reinforced composite material in which collagen fibres are embedded in a gel-like ground substance. Theories derived from ...
al-Zaid N S - - 1988
Collagen from the chorioamnion units from premature and term pregnancies was solubilized by limited pepsin digestion and subjected to SDS-PAG electrophoresis. Collagen types were quantitated by densitometry. It was found that collagen type III decreases and collagen type V tends to increase as gestational age advances. Investigating the relative abundance ...
Smeele L E - - 1988
The temporomandibular joint disk was investigated in fetal and adult human specimens in a morphological study. The dorsal aspect of the disk appears to be composed of a superior, an intermediate and an inferior lamina, thus forming a trilaminar zone. The intermediate lamina continues via the petrotympanic fissure into the ...
Pan X X - - 1988
The ability of Li+ to promote the assembly of actin has been compared with the more common cations used in actin assembly assays, K+, Mg2+, and Ca2+. The principal assay of actin assembly utilized was fluorescence photobleaching recovery (FPR), from which it is possible to determine the fraction of actin ...
Ghosh P - - 1987
It is now well established that the meniscus performs a number of roles that are important to the efficient performance of the knee joint. Of particular importance is the recognition of its load-bearing function and its stabilization of the joint during flexion-extension. The compression of the wedge-shaped meniscus during loading ...
Clarkson T W - - 1987
A massive outbreak of methylmercury poisoning took place in the winter of 1971-1972 due to the consumption of homemade bread contaminated with a methylmercury fungicide. The longitudinal analysis of the mother's head hair, collected after delivery of the baby, provided a means of recapitulating exposure to methylmercury during pregnancy. Methylmercury ...
Marsh D O - - 1987
Pregnant women consumed bread that was prepared from methylmercury-treated wheat. Single strands of maternal head hair were analyzed by x-ray fluorescence spectrometry. The index of fetal exposure was the maximum hair mercury concentration during gestation. Effects were measured by the frequency of psychomotor retardation, seizures, and neurological signs in the ...
Schellenberg J C - - 1987
The ontogenesis of elastin (desmosine), collagen (hydroxyproline), and DNA concentrations and their rates of increase were studied in fetal sheep lungs from day 60 until term. Elastin increased 13-, 17-, 63- and 11- fold in nondissected parenchyma, dissected (free of tubular structures of greater than 0.1 mm diameter) parenchyma, pleura, ...
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