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Results 251 - 300 of 484
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Boischio A A - - 1998
Mercury releases from gold mining occurred during the 1980s in the Upper Madeira river, a Southern tributary of the Amazon. Downstream from these areas, riverside residents rely on fish consumption for subsistence. In July of 1993, hair samples were collected for mercury analysis from a group of mothers and their ...
Akiyama M - - 1998
Harlequin ichthyosis (HI) is a severe congenital ichthyosis in which newborn infants are covered with a thick plate of stratum corneum. We examined skin specimens from a variety of regions of the body including the scalp, face, tongue, trunk, upper and lower extremities, digits, palms, and soles of three fetuses ...
Westergren-Thorsson G - - 1998
During pregnancy and involution, an extensive remodelling of the human cervical connective tissue occurs. This cervical ripening is one of the most pronounced physiological remodelling processes known in human connective tissue. To investigate how the remodelling is accomplished, the levels of mRNA for collagen I and III, versican and three ...
Agren M S - - 1998
Hydrogel dressings are gaining increased clinical acceptance as a wound management modality. The purpose of this study was to compare the effect of three amorphous hydrogels with occlusive, control treatment (Tegaderm) on healing of experimental wounds. Eight partial-thickness cutaneous wounds (2.5 cm x 2.5 cm x 0.04 cm) were made, ...
James V J - - 1998
Low-angle synchrotron X-ray diffraction studies of human fetal extensor tendon and skin collagen, centred in time about the period of first major movement by the fetus, indicate that alignment of the tendon collagen fibrils occurs about this time. At this stage there appears to be no detectable structural difference between ...
Iwahashi M - - 1998
AIM: To provide some insight into the aetiology of spontaneous abortion, the contents of type V collagen was investigated in human decidual tissues in spontaneous abortion and normal pregnancy. METHODS: Collagens were extracted from decidual tissues in spontaneous abortion (n = 19) and normal pregnancy (n = 25). The different ...
Namba R S - - 1998
A fetal lamb model was developed to investigate the capacity of fetal articular cartilage for repair after the creation of a superficial defect. Superficial defects, 100 micrometers deep, were made in the articular cartilage of the trochlear groove in the distal aspect of the femur in eighteen fetal lambs that ...
Blecher A M - - 1998
Transient laxity was documented around the end of pregnancy in a woman who had undergone anterior cruciate ligament (ACL) reconstruction 2 months before conception. This temporary laxity in the 3rd trimester and a few months postpartum corresponded to a time when substantial remodeling from large diameter to small diameter collagen ...
Watanabe M - - 1997
The process of the arrangement of D-periodic collagen fibrils and their growth in maturing tail tendon of mice were studied with the association of type VI collagen, from fetal day 10 to 10 weeks after birth. In tail tendons, the amount of collagen fibers gradually increased along with the diameters ...
Shibata S - - 1997
We investigated the immunohistochemical localisation of types II and X collagen as well as the cytochemical localisation of alkaline phosphatase in the developing condylar cartilage of the fetal mouse mandible on d 14-16 of pregnancy. On d 14 of pregnancy, although no immunostaining for types II and X collagen was ...
Arbeláez L F - - 1997
The binding of matrix metalloproteinases-2 and -9 to pregnancy zone protein and alpha2-macroglobulin was studied. The binding was demonstrated by formation of dimeric as well as tetrameric complexes of pregnancy zone protein and by the formation of alpha2-macroglobulin complexes with fast and intermediate mobility in native gel electrophoresis. The complex ...
Stelnicki E J - - 1997
We have developed a new in vivo model for the study of fetal wound healing. Fetal ICR mice (total gestation, 21 days) received a full-thickness incisional wound in the hind limb at gestational day 14 (N = 100). The wound was made with a 28.5-gauge needle that was passed transplacentally ...
Mast B A - - 1997
Fetal wound healing proceeds rapidly with minimal inflammation and fibroplasia and little or no scar formation. These observations have led to the hypothesis that fetal wound healing more closely resembles regeneration rather than adult wound repair. To test this hypothesis, this study used ultrastructural analysis of fetal and adult fibroblasts ...
Cass D L - - 1997
The scarless repair capabilities of the fetus are influenced by the size of the wound and the gestational age of the fetus. Whereas small wounds heal scarlessly, large wounds in the same fetus heal with scar. Myofibroblasts are specialized fibroblasts that express alpha-smooth muscle actin (alpha-SMA), a contractile cytoskeletal protein. ...
Spitz L - - 1997
This report describes separation of thoraco-omphalopagus conjoined twins and management of the hepatobiliary complications that ensued. The livers were fused and, although both infants had gallbladders, the extrahepatic biliary trees were fused. After separation, obstructive jaundice developed in one twin and she required a biliary diversion. The other twin had ...
Donley T G - - 1997
Controlled-release, tetracycline-impregnated periodontal fibers offer a promising treatment for recurrent adult periodontitis when they are used as an adjunct to scaling, root planing and surgery. In the conventional placement technique, the surface tissue topography is changed by the layer of set adhesive holding the fiber in place, and patients often ...
Cass D L - - 1997
The early-gestation fetus heals incisional skin wounds rapidly and scarlessly. The morphology with which the fetus heals excisional skin wounds remains unclear. To characterize excisional fetal wound repair, and to determine whether there is a developmentally regulated wound-size threshold beyond which fetal skin heals with scar, the authors created excisional ...
Meng J - - 1997
Evidence of hair from several extinct mammals has been recovered from a rich accumulation of fossil excrement from the Late Palaeocene beds of Inner Mongolia, China. This highly unusual and previously undocumented depositional occurrence consists of hundreds of mammalian carnivore coprolites (fossil faeces) and a lesser number of probably raptorial ...
Agren M S - - 1997
BACKGROUND: Little objective information is available on the influence of occlusive dressings on the healing of cutaneous full-thickness wounds. OBJECTIVE: Our purpose was to examine the effects of three occlusive dressings-two hydrocolloid dressings (Comfeel Ulcer Dressing, Coloplast A/S, Espergaerder, Denmark [hydrocolloid dressing A] and DuoDERM; ConvaTec, Princeton, N.J. [hydrocolloid dressing ...
Sawai T - - 1997
Fetal wound healing proceeds without fibrosis or scar formation in contrast to adult wound healing. The mechanisms responsible for this remarkable process are mediated in part through a fetal wound extracellular matrix rich in hyaluronic acid (HA). Polyvinylalcohol sponge (PVA) wound implants were placed pervertebrally at 24 days' gestation in ...
Strek P - - 1997
The vascular pattern of the injected with Mercox human fetal larynges, especially of the anterior commissure and surrounding it area, was analysed within the horizontal and frontal sections under a light microscope. The main result of our study was confirmation of existence of the avascular "plane zero" situated above the ...
Casey M L - - 1997
The tensile strength of human fetal membranes is attributable to interstitial collagens of the zona compacta of the avascular amnion. Collagen fiber strength and proteolytic resistance is provided by inter and intramolecular cross-links of collagen fibrils, which are formed in a series of reactions initiated by lysyl oxidase. Lysyl oxidase ...
Tsambaos D - - 1997
Using a new computerized methodological procedure a separate analysis and a quantitative determination of the viscous and elastic parameters of the scalp hair shaft were performed in 37 neonates of both sexes with a gestational age of 28-29 weeks (n = 16) and 39-40 weeks (n = 21), respectively. A ...
Shandley L - - 1997
The tensile strength of fetal membranes is largely due to their collagen content. In this study we have examined the changes in collagen in the amniotic and allantoic membranes of the sheep over a wide gestational range (27-142 days of gestation; term, 145-150 days). The results have been correlated with ...
West D C - - 1997
The lack of scarring and fibrosis in healing fetal skin wounds may relate to a prolonged presence of hyaluronan (HA). It has been suggested that fetal wounds may lack hyaluronidase, but the hyaluronidase levels in fetal wounds remain unknown. The size of HA influences its biological action, especially in relation ...
Fischer D C - - 1996
Profound changes occur in the uterine cervix during pregnancy. In particular, the extracellular matrix of the connective tissue is remodelled extensively. To elucidate the mechanisms involved in this process, we have analysed the proteoglycan pattern in the human cervix from pregnant and non-pregnant women. Proteoglycans of the cervix tissue specimen ...
Nakano T - - 1996
Comb and wattle tissues, which consist of layers of epidermis, dermis and central connective tissue, are known to contain sulphated glycosaminoglycans (GAGs) including dermatan sulphate and chondroitin sulphate-dermatan sulphate copolymers. Little is known about distribution of these CAGs in each tissue. The objective of this study was to localise sulphated ...
Ozeki H - - 1996
Mammalian melanins exist in two chemically distinct forms: the brown to black eumelanins and the yellow to reddish-brown pheomelanins. They can be quantified by HPLC analysis of pyrrole-2,3,5-tricarboxylic acid (PTCA) and aminohydroxyphenylalanine (AHP). We recently developed a spectrophotometric method for assaying the total amount of eu- and pheomelanins by dissolving ...
Hwang E H - - 1996
Epigastric heteropagus refers to unequal and asymmetric conjoined twins in which the dependent component (parasite) is smaller and usually attached to the epigastrium of the dominant component (autosite). Epigastric heteropagus is a very rare type of conjoined twins. It is generally assumed that conjoined twins represent a form of monozygotic ...
Srinathan S K - - 1996
Gastroschisis is a congenital anomaly in which the intestines are exposed to amniotic fluid throughout fetal life. Previous studies in animal models have demonstrated smooth muscle thickening and decreased contractility, epithelial dysfunction, and submucosal thickening. The present studies were done to further define the mechanism of submucosal changes by investigating ...
Iwahashi M - - 1996
To provide some insight into the etiology of spontaneous abortion, the expression of type IV collagen was investigated in human decidual tissues obtained after spontaneous abortion (n = 17) and normal pregnancy (n = 22). Indirect immunofluorescent staining was performed for type I, III, and IV collagen as well as ...
Schor S L - - 1996
Wound healing in the adult is commonly compromised by excessive scar formation. In contrast, fetal wound healing is a regenerative process characterised by the conspicuous absence of scarring. Available evidence suggests that phenotypic differences between fetal and adult fibroblasts are important determinants of these distinct modes of tissue repair. In ...
Bieńkiewicz A - - 1996
During late pregnancy, the influence of PGF2 alpha and PGE2 on the collagen concentration in a rat's uterus was analysed. In order to evaluate the influence of endogenous prostaglandins and leukotrienes on connective tissue metabolism, a cyclooxygenase inhibitor (Diclofenac) and a dual cyclo-and 5-lipoxygenase inhibitor (BW755C) were administered prior to ...
Simon M M - - 1996
Using a human skin/severe combined immunodeficient (SCID) chimeric mouse model, we examined the keratinocyte expression of the thrombospondin receptor (CD36) and its ligand thrombospondin-1 (TSP1) in acute uninflamed wounds. Positive suprabasal keratinocyte expression of CD36 was observed as early as 30 minutes after wounding in the adjacent, intact epidermis; it ...
Crawley A C - - 1996
We report studies that suggest enzyme replacement therapy will result in a significant reduction in disease progression and tissue pathology in patients with Maroteaux-Lamy syndrome (Mucopolysaccharidosis type VI, MPS VI). A feline model for MPS VI was used to evaluate tissue distribution and clinical efficacy of three forms of recombinant ...
Ali A M - - 1996
The purpose of this study was to determine the effect of surgical induction of anterior disk displacement (ADD) on type-III, VI and IX collagens of the rabbit craniomandibular joint (CMJ) tissues using an immunohistochemical technique. The right joint was exposed surgically, all discal attachments were severed except for the posterior ...
Shibata S - - 1996
The first indication of cartilage formation was detected on day 14.5 of pregnancy in close connection to the ossifying mandible. A separated blastema was never observed. Thus the findings support the concept that the condylar cartilage develops from already differentiated cells, not from primary undifferentiated mesenchymal cells. Moreover, endochondral bone ...
Spencer R - - 1995
The myth of rachipagus twins is hereby exploded-the myth, not the rachipagus! In a review of over 1,200 cases of conjoined twins, one classic example of rachipagus was found-two complete infants with dorsal union of the entire head and trunk, with roentgenograms showing clearly visible bony union of the vertebral ...
Nanney L B - - 1995
Vibriolysin, a new agent for enzymatic debridement, was recently shown to rapidly and thoroughly hydrolyze burn wound eschar within full-thickness wounds. The safety of this agent and its subsequent effect on wound healing processes have yet to be established and are addressed in this study. Within the context of a ...
Karmody C S - - 1995
Malformations of the auricle are not uncommon and occur in 1 out of 12500 births. They can occur alone or can be associated with genetically determined syndromes. Most congenital malformations in the human occur during the third to twelfth weeks of embryonic life. During this period, the external ear is ...
Sullivan K M - - 1995
BACKGROUND: Fetal skin heals by regeneration rather than by adult-type scarring. Prior studies indicate that scarless healing is an intrinsic property of fetal tissue. METHODS: To answer the question of whether fetal tissue could influence the healing of adjacent adult tissue, adult sheepskin was transplanted on the backs of 60-days' ...
Fukuyama S - - 1995
To clarify the effect of mechanical stress on hypertrophy of the ligamentum flavum (LF), we compared the thicknesses, histological findings, and total collagen content of 161 lumbar LF in two groups defined by radiographic signs. LF with one or more signs of spondylolisthesis, disk degeneration, vacuum phenomenon, traction spur, or ...
Nakamura E - - 1995
We investigated the effects of tibial lengthening by callotasis on glycosaminoglycan (GAG) metabolism of the knee articular cartilage in 30 rabbits. The distraction rate was 1 mm per day. On the right side, the daily distraction was in 2 steps, while on the left it was in 120 steps. The ...
Cernichiari E - - 1995
The concentration of total mercury in maternal hair during pregnancy was used as a measure of fetal exposure to methylmercury in a study of a fish-eating population in the Seychelles islands. A segment of scalp hair approximately 10 centimeters in length, that grew during pregnancy, was selected for measurement. Total ...
Mylona P - - 1995
The pattern of type VI collagen deposition in human endometrium throughout the menstrual cycle and in decidua of the first trimester of pregnancy was studied. Immunohistochemical analysis demonstrated a dense microfibrillar network of collagen VI in the stroma of preimplantation endometrium which was reduced during the peri-implantation period and no ...
Kaidi R - - 1995
Uteri were collected at the slaughter of non-pregnant dairy cattle and cattle at various stages of gestation. The weight of the whole uterus increased about 12-fold during the 9 month gestation period. The greatest increase was in the weight of the pregnant horn. The increase in weight of the uterine ...
Dharap A S - - 1994
618 Malay subjects were selected randomly to find out the frequency and patterns of hair distribution on the phalanges of their hands. Hair on the proximal phalanx was absent in 2% of the males and in 3.3% of the females. The middle phalangeal hair (MPH) was absent in 78% of ...
Bieńkiewicz A - - 1994
In order to study the role of Platelet Activating Factor (PAF) in the mechanism of parturition and connective tissue metabolism in the pregnant rat uterus, we investigated the influence of the Platelet Activating Factor Receptor Antagonist (BN 52021) on gestation duration and collagen concentration in pregnant rat uterus and cervix ...
Raghunath M - - 1994
We have developed a method for early prenatal diagnosis of molecular disorders of collagens I and III. The method takes advantage of the fact that isolated chorionic villi contain significant amounts of collagens in their extracellular matrix (stroma) and that they synthesize collagens in vitro. After metabolic labeling of chorion ...
Robinson P D - - 1994
The timing of temporomandibular joint (TMJ) development in the cotton-eared marmoset was studied by histological examination of joints taken during embryogenesis and compared with TMJ development reported in man. Specimens were obtained via hysterotomy at intervals during pregnancies dated by estimation of uterine size or fetal head diameter. Elements of ...
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