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Chousawai Saruta - - 2012
To determine the efficacy of the rapid biophysical profile (rBPP), which includes sound-provoked fetal movement detected by ultrasonography, and amniotic fluid index for antepartum fetal well-being assessment in suspected intrauterine growth restriction (IUGR) fetuses. One hundred seven tests of rBPP were antenatally performed in 30 IUGR fetuses who attended the ...
Gorayeb Ricardo - - 2012
The study's objective was to assess the effect of a cognitive behavioral group intervention on the pregnancy rates of patients submitted to in vitro fertilization (IVF) techniques or to intracytoplasmic sperm injection (ICSI). The study was conducted on 188 patients, 93 who participated in a group of psychological intervention before ...
Black Amanda Y - - 2012
Adolescent pregnancy remains a public health issue with significant medical, emotional, and societal consequences for the adolescent mother, her child, and her family. Teenage pregnancies are at higher risk of many adverse outcomes, including preterm delivery, low birth weight, and neonatal and infant mortality. Teen pregnancy and motherhood may have ...
Simon Witold - - 2012
Abstract The New Experience for Survivors of Trauma (NEST) is a group psychotherapy intervention for clients traumatized by consequences of abuse, neglect, and pregnancy loss. This multiple site study is the first investigation of its effectiveness. Ninety outpatients from a naturalistic setting completed the Symptom Checklist and the Sense of ...
Coussons-Read Mary E - - 2012
There is mounting evidence that stress during pregnancy can have detrimental effects on gestation and birth. Existing studies indicate that prenatal stress may increase levels of circulating inflammatory markers that are associated with prematurity and pregnancy complications, suggesting that stress-related changes in the cytokine milieu may increase the risk of ...
Grasselli Giacomo - - 2012
We describe the case of a 25 year-old woman at 27 weeks of gestation who was admitted to our intensive care unit (ICU) for acute respiratory distress syndrome (ARDS) caused by pandemic 2009 H1N1 influenza A. She presented with septic shock and refractory hypoxemia unresponsive to rescue therapies such as ...
Patel Ashlesha - - 2012
A random sample (20%) of U.S. and territorial emergency departments were surveyed in 2004 and again in 2009 to obtain information about provision and counseling of emergency contraception (EC) to sexual assault victims. A representative sample of 20% of hospitals, stratified by state/ territory was prepared from the American Hospital ...
Oyelese Yinka - - 2012
The placenta and umbilical cord are crucial to the survival and well-being of the fetus. In fact, disorders of either of these may lead to fetal death or severe morbidity. Yet, they are often not accorded appropriate attention in the prenatal sonographic examination. Similarly, the amniotic fluid often reflects the ...
Sahmani Mehdi M Department of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, - - 2012
Peroxisome proliferative-activated receptors (PPARs) are nuclear receptors that involved in cellular lipid metabolism and differentiation. The subtype γ of the PPAR family (PPARγ) plays important roles in physiologic functions of ovaries. To determine correlation between PPARγ protein level in granulosa cells and pregnancy rate in women undergoing in-vitro fertilization (IVF) ...
Hui Choi W H - - 2012
hui choi w.h., lee g.l., chan c.h.y., cheung r.y.h., lee i.l.y. & chan c.l.w. (2012) The relationships of social support, uncertainty, self-efficacy, and commitment to prenatal psychosocial adaptation. Journal of Advanced Nursing00(0), 000-000. doi: 10.1111/j.1365-2648.2012.05962.x ABSTRACT: Aims.  To report a study of the relations of prenatal psychosocial adaptation, social support, demographic ...
Fung A M - - 2012
Obstructive sleep apnea (OSA) is characterized by repeated episodes of upper airway obstruction, resulting in hypoxemia, hypercapnia and sleep fragmentation. Pathophysiological sequelae include sympathetic activation, increased oxidative stress and a generalized inflammatory response, culminating in endothelial dysfunction. These are the proposed mechanisms that mediate the increased risk of hypertension and ...
East Patricia L - - 2012
The authors used cross-lagged analyses to examine the across-time influences on and consequences of adolescents' pregnancy intentions, wantedness, and regret. One hundred pregnant Latina adolescents were studied during pregnancy and at 6 and 12 months postpartum. The results revealed 4 main findings: (a) similar to what has been found in ...
Facchinetti Fabio - - 2012
The pathogenesis of preterm birth (PTB) is largely unknown and the endocrine stress pathway is likely to participate in the mechanisms allowing onset of labor. However, the vast majority of the studies evaluating psychosocial distress denied an association with PTB. Uterine contractility rather than PTB seems associated with distress in ...
Forczek Wanda - - 2012
When a woman becomes pregnant her body undergoes tremendous changes hormonally and anatomically. Our survey revealed very little literature on biomechanics of gait in gravidas and lack of consensus among scientists in pregnancy-related mechanisms of body adaptation. That is why the authors felt encouraged to determine the effect of pregnancy ...
Kraft Rory E - - 2012
Abstract:Michigan's Appellate Court ruled in 2004 that a pregnancy that resulted from a rape should be considered a bodily injury for sentencing purposes. Interestingly, all three possible outcomes of a pregnancy-abortion, miscarriage, or childbirth-are considered to bring with them significant and substantial physical, psychological, and emotional changes. While the immediate ...
Hofmeyr G Justus - - 2012
Piracetam is thought to promote the metabolism of brain cells when they are hypoxic. It has been used to prevent adverse effects of fetal distress. The objective of this review was to assess the effects of piracetam for suspected fetal distress in labour on method of delivery and perinatal morbidity. ...
El-Hage Wissam - - 2012
The aim of the study was to characterize the maternal dimensions of anxiety, depression and prenatal attachment in women undergoing an amniocentesis. A prospective observational study was conducted. Women were referred to early amniocentesis for increased nuchal translucency, elevated biochemical markers or advanced maternal age. All participants had 3 prenatal ...
Lukasse Mirjam - - 2012
Few studies have investigated the impact of sexual violence on health during pregnancy. We examined the association between sexual violence and the reporting of physical symptoms during pregnancy. A population-based national cohort study conducted by The Norwegian Mother and Child Cohort study (MoBa) collected data from pregnant women through postal ...
Myers Dean A - - 2012
By late gestation, the maturing hypothalamo-pituitary-adrenal (HPA) axis aids the fetus in responding to stress. Hypoxia represents a significant threat to the fetus accompanying situations such as preeclampsia, smoking, high altitude, and preterm labor. We developed a model of high-altitude (3,820 m), long-term hypoxia (LTH) in pregnant sheep. We describe the ...
Vila-Vives José María JM Department of Obstetrics, La Fe University Hospital, Bulevar Sur s/n, 46026 Valencia, - - 2012
Arthrogryposis multiplex congenital is a rare condition defined as contractures in multiple joints at birth due to disorders starting in fetal life. Its etiology is associated with many different conditions and in many instances remains unknown. The final common pathway to all of them is decreased fetal movement (fetal akinesia) ...
Rezaee Zahra Z Obstetrics and Gynecology Department, Tehran University of Medical Sciences, Tehran, - - 2012
Polycystic ovarian syndrome (PCOS) is one of the most common causes of endocrine disorders and main reasons for infertility due to unovulation and recurrent abortions. There is no consensus on effect of serum progesterone level on the day of human chorionic gonadotropin (hCG) injection. This study aims to evaluate the ...
Lanik Aaron D - - 2012
The preconception counseling visit is an ideal time to evaluate the patient and her future expectations regarding pregnancy. In fact at every patient encounter, whether for acute or chronic care, consideration should be given to any woman who, although not pregnant, may become pregnant, and what effect each ordered procedure, ...
Fenwick Jennifer - - 2012
To explore and describe men's experiences of pregnancy and childbirth expectations. There remains limited work exploring expectant father's perspectives. Qualitative descriptive design. Twelve Australian expectant fathers participated in between 1 and 2 interviews during pregnancy and 1 after childbirth (32 in total). Six fathers also chose to submit a number ...
Clark Kit - - 2011
Pregnancy is not always an expected or happy event. When a woman is facing an unplanned pregnancy, it can be a very difficult emotional experience. As with any pregnancy, working in a prenatal setting can impact how a woman feels about and handles her pregnancy. Once again, one genetic counselor ...
Smith Debbie M - - 2011
Although the association between young pregnancy and the socio-economic environment is globally recognised, little is understood about either the processes behind it or how young parents construe this relationship. Twenty-one semi-structured interviews were conducted in four London areas; two 'less deprived' and two 'more deprived' in order to solicit young ...
Johnson Anita - - 2011
This is an interview with a young parent about her experience of being pregnant at 17. NICE released their guidelines in October 2010 to recommend a flexible model of tailored antenatal care for young parents. Prior to this Bath had set up a Young Parents' One Stop Shop offering antenatal ...
Lewis Christa M - - 2011
: Delivery mode following midurethral sling remains controversial. There are no formal guidelines as to the preferred mode of delivery following midurethral sling. : A 33-year-old gravida 2 para 2 underwent midurethral sling placement 16 months after the delivery of her first child for severe stress urinary incontinence (SUI). She ...
Incerti Maddalena - - 2011
Objective. To evaluate the relation between duration of placental exposure to recently passed meconium in vivo and histologic evidence of meconium uptake by macrophages. Design. Retrospective cohort. Setting. University Hospital. Population. A total of 44 term deliveries of singleton infants with moderate or thick meconium had placental examination and documented ...
Al Banna Rashed R Medical Department, Salmaniya Medical Complex, Manama, Bahrain. - - 2011
A 29-year-old lady G4P3A0 has been admitted in her last trimester with features of peripartum cardiomyopathy. She was treated accordingly with comprehensive antifailure therapy. She lost follow-up but reappeared 12 weeks later with further deterioration of her heart failure, severe depression and osteoporotic multiple lumbar fractures. She turned to be ...
Filippa Verónica - - 2010
The neuroendocrine hypothalamic-pituitary axis undergoes morphological and biochemical changes throughout gestation. In viscacha, pregnancy lasts approximately 154 days, and three stages can be described: early, mid- and late pregnancy. The aim of this work was to study the pituitary LH-gonadotrophs, FSH-gonadotrophs, somatotrophs, corticotrophs and thyrotrophs of non-pregnant and pregnant adult ...
Toth Bettina - - 2010
Cytokines play a fundamental role at the feto-maternal interface. A dysregulation of the cytokine profile could be linked with fetal rejection. This study investigated differences in the expression of the Th1 cytokine interleukin-15 (IL-15) of normal and disturbed pregnancy. Analysis of IL-15 expression by immunohistochemistry and real-time RT-PCR in placental ...
Bohács Anikó - - 2010
Asthma influences pregnancy outcome and pregnancy affects asthma severity, but the immunologic mechanisms of these interactions are not fully elucidated. The prevalence of lymphocyte subsets was identified by cell surface markers and intracellular FoxP3 staining, in healthy non-pregnant (HNP; N = 15), healthy pregnant (HP; N=33), asthmatic non-pregnant (ANP; N=62) and asthmatic ...
Chen Guofang - - 2011
There is a widespread interest in defining factors and mechanisms that stimulate proliferation of pancreatic islet β-cells. Pregnancy is a special periods when the pancreatic islet display a highly reproducible physiological proliferation. However, the molecular mechanism of β-cell proliferation during pregnancy is unclear. Here, we used cDNA expression array to ...
Tirado-González I - - 2010
Recent studies showed that some functions of decidual dendritic cells appear to be essential for pregnancy. In humans, decidual dendritic cells are identifiable by their expression of DC-SIGN. We compared the subpopulations of human decidual DC-SIGN+ cells from first-trimester normal pregnancies and spontaneous abortions by flow cytometry. In normal decidua, ...
Parham Peter - - 2010
During embryo implantation and initiation of pregnancy, uterine NK (uNK) cells engage invasive fetal trophoblasts to remodel vessels that conduct blood to the placenta. This partnership, involving uNK cell receptors that recognize HLA-C ligands on trophoblasts, varies the course of human pregnancy because the genes for both receptors and ligands ...
Hiby Susan E - - 2010
Many common disorders of pregnancy are attributed to insufficient invasion of the uterine lining by trophoblast, fetal cells that are the major cell type of the placenta. Interactions between fetal trophoblast and maternal uterine NK (uNK) cells--specifically interactions between HLA-C molecules expressed by the fetal trophoblast cells and killer Ig-like ...
Koh Kwi Hye - - 2011
Human pregnancy is known to influence hepatic drug metabolism in a cytochrome (P450)-specific manner. However, the underlying mechanisms remain unknown, in part due to a lack of experimental models to study altered drug metabolism during pregnancy. In this study, we examined how pregnancy influences expression of major P450 isoforms in ...
Wegienka Ganesa G Department of Biostatistics and Research Epidemiology, Henry Ford Hospital, Detroit, MI 48202, USA. - - 2011
Regulatory T cells (Treg cells) are an important area of investigation in human health and disease. In this study, the trajectory of percentage of Treg cells (defined as CD4+CD25+Foxp3+CD127--lymphocytes) was measured in the blood of 208 women during pregnancy and up to three additional times in the postpartum period (1, ...
Gatson Natosha N NN Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, 760 Biomedical Research Tower, 460 W 12th Avenue, Columbus, OH 43210-1239, United - - 2011
Multiple sclerosis (MS) is a demyelinating disease of the CNS involving T cell targeting of myelin antigens. During pregnancy, women with MS experience decreased relapses followed by a post partum disease flare. Using murine experimental autoimmune encephalomyelitis, we recapitulate pregnancy findings in both relapsing and progressive models. Pregnant mice produced ...
Schraenen A - - 2010
Upregulation of the functional beta cell mass is required to match the physiological demands of mother and fetus during pregnancy. This increase is dependent on placental lactogens (PLs) and prolactin receptors, but the mechanisms underlying these events are only partially understood. We studied the mRNA expression profile of mouse islets ...
Kaloglu Celal - - 2010
The endometrial extracellular matrix (ECM) remodelling has a crucial role in the establishment of a successful pregnancy. In addition to its basic function such as regulation of cell function, differentiation, migration, proliferation, the substantial alterations in the endometrial ECM may play a specific role in the trophoblast invasion, placentation, cell ...
Towers Craig V - - 2010
To evaluate the absolute CD4+, CD8+, and lymphocyte cell counts and percentages from the first trimester through 6-12 weeks post-delivery in normal human immunodeficiency virus (HIV)-negative pregnant patients. A longitudinal laboratory analysis was performed during pregnancy that involved 51 HIV-negative subjects with blood analysis obtained in all trimesters, at delivery, ...
Sambucci Manolo - - 2010
Abstract During embryogenesis, the development of tissues, organs and systems, including the immune system, is particularly susceptible to the effects of noxious agents. We examined the effects of prenatal (in utero) exposure to WiFi signals on pregnancy outcome and the immune B-cell compartment, including antibody production. Sixteen mated (plug-positive) female ...
Southcombe Jennifer - - 2010
Invariant natural killer T (iNKT) cells are implicated in the pathogenesis of several diseases. They influence both innate and adaptive immune responses through their capacity to rapidly produce large quantities of cytokines upon activation. During pregnancy maternal immunity is biased towards type 2 cytokine production to regulate type 1 cytokines ...
Mao Guanping - - 2010
Mechanisms maintaining the growth of a "semi-foreign" fetus within the maternal uterus via immune tolerance remain unclear. CD4(+)CD25(+) regulatory T (Treg) cells have been implicated in the maintenance of maternal-fetal immune tolerance. Additionally, 17β-estradiol (E2) is able to initiate immune suppression through CD4(+)CD25(+) Treg cells during early pregnancy. Little is ...
Cartwright Judith E - - 2010
In human pregnancy, successful placentation and remodelling of the uterine vasculature require the integration of a number of stages, which are crucial for a healthy pregnancy. As the demands of the developing fetus for nutrients and oxygen increase, the capacity of the maternal blood vessels to supply this must be ...
Sun Xiaofei X Division of Reproductive Sciences, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, - - 2010
In most mammals, placentation is critical for fetal development and pregnancy success. Exposure to marijuana during pregnancy has adverse effects, but whether the placenta is a target of cannabinoid/endocannabinoid signaling is not known. Using mice as a model system, we found that the endocannabinoid system is present in the ectoplacental ...
Lin Xing-guang - - 2010
Estrogen as well as CD4(+)Foxp3(+) regulatory T cells were shown to have a protective role not only in maintaining maternal-fetal tolerance but also against autoimmune diseases. We aimed to investigate whether the pregnancy levels of estrogen are enough to induce transplant tolerance as to maintain fetal-maternal tolerance. We established H-Y ...
Troeger Carolyn - - 2010
Transplacental traffic of fetal progenitor and differentiated cells is a well-known phenomenon in pregnancies. We hypothesize that intrauterine stem cell transplantation leads to microchimerism in the dams and that this is gestational age-dependent. EGFP+ fetal liver-derived mesenchymal stem cell (MSC) (10(5) per fetus) were injected intraperitoneally into congeneic and allogeneic ...
Jonsson Anna Maria - - 2010
During pregnancy small amounts of cells pass between the mother and the fetus, and this transfer may give rise to a chimeric state that persist for years in both individuals. Both fetal and maternal microchimerism (MMc) have been associated with different autoimmune disorders. Information about MMc in tissues of healthy ...
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