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Whisner Corrie M CM Division of Nutritional Sciences, Cornell University, Ithaca, - - 2014
Few studies have examined the effect of maternal calcium intake and vitamin D status on bone health across gestation in pregnant adolescents. This study aimed to characterize maternal bone quality and determinants of bone quality change across gestation in pregnant adolescents. Healthy pregnant adolescents (n = 156; aged 13-18 y) with singleton ...
Malti N N Laboratory of Physiology, Physiopathology and Biochemistry of Nutrition, Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe, University ABOU-BEKR BELKAÏD, Tlemcen 13000, - - 2014
To determine oxidative stress markers in maternal obesity during pregnancy and to evaluate feto-placental unit interaction, especially predictors of fetal metabolic alterations. 40 obese pregnant women (prepregnancy BMI > 30 kg/m²) were compared to 50 control pregnant women. Maternal, cord blood and placenta samples were collected at delivery. Biochemical parameters (total cholesterol and ...
Thayer Zaneta M ZM Department of Anthropology, University of Colorado Denver, Denver, Colorado, - - 2014
Maternal hypothalamic pituitary adrenal-axis function regulates production of the stress hormone cortisol, which during pregnancy can cross the placenta and have lasting impacts on fetal growth and development. This article provides a preliminary test of the hypothesis that a woman's socioeconomic status (SES) predicts her cortisol during pregnancy and her ...
Young Bridget E BE *Division of Nutritional Sciences, Cornell University, Ithaca, New York, - - 2014
The purpose of the study was to identify determinants of placental vitamin D receptor (VDR) expression and placental calcium (Ca) transfer among pregnant adolescents. Placental tissue was obtained in 94 adolescents (≤18 yr) at term. In 12 of these teens, stable Ca isotopes were given intravenously ((42)Ca) and orally ((44)Ca) ...
Mano Yukio Y Departments of Pathology and Biological Responses; Gynecology and - - 2014
Molecular hydrogen (H2) scavenges hydroxyl radicals. Recently, H2 has been reported to prevent a variety of diseases associated with oxidative stress in model systems and in humans. Here, we studied the effects of H2 on rat fetal hippocampal damage by ischemia and reperfusion (IR) on day 16 of pregnancy with ...
Vidal Zendy Evelyn Olivo ZE Instituto de Salud Pública, Universidad Veracruzana, Avenida Luís Castelazo Ayala S/N, Col. Industrial Ánimas, Xalapa, Veracruz, - - 2014
Iodine is an essential element trace for the synthesis of maternal thyroid hormones needed to support normal fetal development; it also acts as an antioxidant directly or induce antioxidant enzymes indirectly. Iodine deficiency and oxidative stress are associated with pregnancy complications. This study aimed to assess the urinary iodine concentration ...
Feola Andrew A Cluster Organ Systems, Department Development and Regeneration, Faculty of Medicine, KU Leuven, Leuven, - - 2014
The vagina and surrounding structures have been shown to remodel during pregnancy. Our objective was to characterize the biomechanical properties of the vagina in the rodent model in vivo utilizing three-dimensional (3D) ultrasound. The vagina was visualized by ultrasound after distention by increasing pressures throughout pregnancy (15 and 18 days) and ...
Cole-Lewis Heather J - - 2014
Objective: There is evidence that pregnancy-specific stress is associated with preterm birth. The purpose of this study is to examine the association between change in pregnancy-specific stress over the course of pregnancy and birth outcomes (i.e., preterm birth and gestational age) in an understudied but vulnerable group using a theoretically ...
Redman C W CW The John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom. Electronic address: - - 2014
Incomplete spiral artery remodelling is the first of two stages of pre-eclampsia, typically of early onset. The second stage comprises dysregulated uteroplacental perfusion and placental oxidative stress. Oxidatively stressed syncytiotrophoblast (STB) over-secretes proteins that perturb maternal angiogenic balance and are considered to be pre-eclampsia biomarkers. We propose that, in addition ...
Cotechini Tiziana T Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada K7L - - 2014
Fetal growth restriction (FGR) and preeclampsia (PE) are often associated with abnormal maternal inflammation, deficient spiral artery (SA) remodeling, and altered uteroplacental perfusion. Here, we provide evidence of a novel mechanistic link between abnormal maternal inflammation and the development of FGR with features of PE. Using a model in which ...
Yoshida Kyoko - - 2014
The remodeling of the cervix from a rigid barrier into a compliant structure, which dilates to allow for delivery, is a critical process for a successful pregnancy. Changes in the mechanical properties of cervical tissue during remodeling are hypothesized to be related to the types of collagen crosslinks within the ...
Pajand Peyman P Azad Islamic University-Damghan Branch, Damghan, - - 2014
Objective(s): Stress induces many homeostatic aberrations which are followed by lifelong allostatic responses. Epilepsy is developed or influenced by different environmental factors, i.e. prenatal stress which makes many contradictory developmental changes in seizure threshold and intensity. We investigated the potential seizure response of the rat offspring to prenatal stress; the ...
Leuner Benedetta B Departments of Psychology and Neuroscience, The Ohio State University, Columbus, Ohio, United States of - - 2014
Postpartum depression, which affects approximately 15% of new mothers, is associated with impaired mother-infant interactions and deficits in cognitive function. Exposure to stress during pregnancy is a major risk factor for postpartum depression. However, little is known about the neural consequences of gestational stress. The medial prefrontal cortex (mPFC) is ...
Singh Sarika S Department of Pathology, Lady Hardinge Medical College, New Delhi, DL 110001, - - 2014
Gestational trophoblastic diseases (GTD) are a heterogenous group of disorders that arise from trophoblastic epithelium. They can follow molar pregnancy (50%), abortions (25%), normal pregnancy (22.5%), and ectopic pregnancy (2.5%) [Robert JK, Lora HE, Brigitte MR (ed) Blaustein Pathology of the Female Genital Tract 6th edn (Springer) pp. 1101-7]. Occurrence ...
Daniel Nnadi N Department of Obstetrics & Gynaecology, Usmanu Dan-Fodio University Teaching Hospital (UDUTH), PMB 2370, Sokoto, - - 2014
This is a report on a 72-year-old postmenopausal woman who presented with passage of fetal bones through an umbilical fistula. She was diagnosed as a case of demised abdominal pregnancy, which had been retained for 26 years. She subsequently had exploratory laparotomy, evacuation of the abdominal pregnancy, hysterectomy, and bowel ...
Hildingsson Ingegerd I Mid Sweden University, Department of Nursing, Holmgatan 10, SE-85170 Sundsvall, Sweden; Uppsala University, Department of Women's and Children's Health, Uppsala, Sweden; Karolinska Institutet, Department of Women's and Children's Health, Sweden. Electronic address: - - 2013
to compare self-rated health and perceived difficulties during pregnancy as well as antenatal attendance, birth experience and parental stress in fathers with and without childbirth related fear. a longitudinal regional survey. Data were collected by three questionnaires. three hospitals in the middle-north part of Sweden. 1047 expectant fathers recruited in ...
Loy See-Ling SL a Nutrition Program, School of Health Sciences, Universiti Sains Malaysia , Kelantan , - - 2013
Abstract This study aimed to examine the associations among prenatal nicotine exposure, oxidative stress and postpartum visceral fat among women exposed to secondhand smoke (SHS). The study was conducted in Kelantan, Malaysia, from April 2010 to December 2012. Blood samples were collected in the second and third trimesters from 135 ...
Yiyenoğlu Ozgür Bilgin - - 2013
To determine the levels of oxidative stress markers in recurrent pregnancy loss using a novel automated method. 30 pregnant women in their first trimester with a history of recurrent pregnancy loss (RPL) and 30 healthy pregnant women were enrolled in this prospective controlled study. Total antioxidant capacity (TAC), total oxidant ...
Negi Reena - - 2013
Pre-eclampsia is a devastating multi system syndrome and a major cause of maternal, fetal, neonatal morbidity and mortality. Pre-eclampsia is associated with oxidative stress in the maternal circulation. To have an insight on the effect of pre-eclampsia/eclampsia on the neonates, the study was made to explore the oxidative status by ...
Liou Shwu-Ru SR School of Nursing, Chang Gung University of Science and Technology, Chiayi Campus, - - 2013
to understand the trends in, and relationships between, maternal stress, depressive symptoms and anxiety in pregnancy and post partum. a prospective longitudinal survey study was undertaken to explore maternal psychological distress throughout the perinatal period. The participants were recruited after 24 completed weeks of gestation, and were followed-up monthly until ...
Rudzik Alanna E F - - 2013
The purpose of the study was to examine the relationship between self-reported stress levels among new mothers in São Paulo, Brazil and two biomarkers of stressful experience, oxytocin (OT) and Epstein-Barr Virus antibody level (EBV-ab), with planned pregnancy hypothesized as a moderator of biological response to stressful conditions. Sixty-three first-time ...
Dorrington Sarah - - 2013
International studies indicate that the median prevalence of psychotic experiences in children is 7%. It has been proposed that environmental stress during pregnancy may affect the neurodevelopment of the foetus and lead to a vulnerability in the child to later stressors and psychopathology. In this study we explore the relationship ...
Korkmaz Vakkas - - 2013
Abstract Objective: Iron supplementation was found to be a cause of oxidative stress. The aim of this study was to compare oxidative stress in pregnancies with and without iron supplementation in the first trimester pregnancies. Methods: One hundred and eight women in the first trimester of normal pregnancies were randomly ...
Hall Kelli Stidham KS Department of Obstetrics and Gynecology, School of Medicine, Institute for Social Research, Population Studies Center, University of Michigan, L4000 Women's Hospital, 1500 East Medical Center Dr., Ann Arbor, MI 48109, United States. Electronic address: - - 2014
Depression and stress have been linked with poor contraceptive behavior, but whether existing mental health symptoms influence women's subsequent risk of unintended pregnancy is unclear. We prospectively examined the effect of depression and stress symptoms on young women's pregnancy risk over one year. We used panel data from a longitudinal ...
Shapiro Gabriel D - - 2013
Abstract Aims: Psychosocial stress during pregnancy (PSP) is a risk factor of growing interest in the etiology of preterm birth (PTB). This literature review assesses the published evidence concerning the association between PSP and PTB, highlighting established and hypothesized physiological pathways mediating this association. Method: The PubMed and Web of ...
Lee Seok Hong SH Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, - - 2013
Pregnancy-induced osteoporosis is a rare disorder characterized by fragility fracture and low bone mineral density (BMD) during or shortly after pregnancy, and its etiology is still unclear. We experienced a case of a 39-year-old woman who suffered from lumbago 3 months after delivery. Biochemical evidence of increased bone resorption is ...
Coughlan Carol - - 2013
To determine whether women with recurrent implantation failure (RIF) after in vitro fertilization (IVF), similar to women with recurrent pregnancy loss, have significantly higher stress levels than women without reproductive failure, and to compare stress levels between women with RIF and women with recurrent pregnancy loss. In a questionnaire-based study ...
Mazza Edoardo - - 2013
Measuring the stiffness of the cervix might be useful in the prediction of preterm delivery or successful induction of labour. For that purpose a variety of methods for quantitative determination of physical properties of the pregnant cervix have been developed. Herein we review studies on the clinical application of these ...
Bolten Margarete - - 2013
Hypothalamic-pituitary-adrenal (HPA) activation during pregnancy is linked to dysfunctional behavioral outcomes in the offspring. According to Belsky's differential susceptibility hypothesis, individuals vary regarding their developmental plasticity. Translating the differential susceptibility hypothesis to the field of fetal programming, we hypothesize that infants' temperament, as the constitutionally based reactivity to stimulation, moderates ...
Spicer Julie - - 2013
Pregnant adolescents have high rates of poor birth outcomes, but the causes are unclear. We present a prospective, longitudinal study of pregnant adolescents assessing associations between maternal psychobiological stress indices and offspring gestational age at birth and birthweight. Healthy nulliparous pregnant adolescents were recruited (n=205) and followed during pregnancy. Ambulatory ...
Voellmin Annette - - 2013
The association between maternal psychological state during pregnancy and birth outcomes is well established. The focus of previous studies has been on the potentially detrimental consequences of maternal stress on pregnancy and birth outcomes, particularly shortened gestation and increased risk of preterm birth. Despite a growing literature linking positive affect ...
Bennett Greer A - - 2013
Background: Maternal psychosocial stress during pregnancy is associated with adverse neonatal outcomes. These outcomes result from changes in fetal brain development and lead to disrupted cognitive, behavioural and emotional development. The neurosteroid allopregnanolone has been shown to reduce neural excitability and aid in protecting the fetal brain from excitotoxic insults. ...
Zohsel Katrin - - 2013
Maternal distress during pregnancy has been linked to aggressive behavior in offspring. This effect has been interpreted in terms of 'fetal programming'. The 7-repeat (7r) allele of a VNTR polymorphism in exon III of the human dopamine receptor D4 (DRD4) has consistently been associated with externalizing behavior problems, especially in ...
Papadopoulou Elektra - - 2013
During pregnancy, important hemodynamic changes occur, consistent with an increase in preload and decrease in afterload and systemic vascular resistance. The aim of the present study was to investigate the changes in left ventricular (LV) strain and rotational properties during the 3 trimesters of normal pregnancy and to examine the ...
Brunton Paula J - - 2013
A successful pregnancy requires multiple adaptations in the mother's brain that serve to optimise fetal growth and development, protect the fetus from adverse prenatal programming and prevent premature delivery of the young. Pregnancy hormones induce, organise and maintain many of these adaptations. Steroid hormones play a critical role and of ...
Amugongo Sarah K SK Department of Integrative Biology, University of California, Berkeley, CA 94720, - - 2014
Unperturbed fetal development is essential for future health of an individual. Previous studies have linked diseases of aging to harmful alterations that happen during fetal development. Given the significant long-term impact that intrauterine environment has on an individual's life, it was hypothesized that maternal stress during pregnancy will have negative ...
Reynolds Lawrence P - - 2013
This review discusses the importance of placental vascular development, as reflected by placental angiogenesis and placental blood flow, to placental function in normal pregnancies. We then summarize our current understanding of how maternal stress, including inadequate maternal nutrition as well as the application of assisted reproductive technologies (ART), leads to ...
Takeda Jun - - 2013
Uterine artery embolization (UAE) is a common treatment for post-partum hemorrhage and uterine fibroids. However, the effects of UAE on subsequent pregnancies have not been established. Here, we present a case of spontaneous uterine rupture after previous UAE. A 31-year-old woman underwent UAE for a cervical ectopic pregnancy. Contrast-enhanced magnetic ...
Soberanes-Chávez Paulina - - 2013
Inhalant misuse starts at an early age and a large number of users are women in reproductive age. This study investigates whether exposure to toluene, a commonly misused solvent, alone or combined with restraint stress during pregnancy, produces adverse effects in pregnant mice and their offspring during lactation and adulthood. ...
Brunton Paula J - - 2013
A sub-optimal in utero environment, for example as a result of maternal stress can have detrimental effects on the pregnancy and long-term adverse 'programming' effects on the offspring. The focus here is on the effects of prenatal social stress on the mother, her pregnancy and the offspring, since these issues ...
Lieben L - - 2013
Pregnancy challenges maternal calcium handling because sufficient calcium has to be transferred to the fetus to ensure fetal bone mass acquisition. 1,25(OH)2vitaminD [1,25(OH)2D] is an important regulator of calcium homeostasis during adulthood, yet its role seems redundant for the maternal adaptations to pregnancy as well as during fetal development. However, ...
Christian Lisa M - - 2013
ObjectiveAfrican Americans experience preterm birth at nearly twice the rate of whites. Chronic stress associated with minority status is implicated in this disparity. Inflammation is a key biological pathway by which stress may affect birth outcomes. This study examined the effects of race and pregnancy on stress-induced inflammatory responses.MethodsThirty-nine women ...
Yu Yunxian - - 2013
This study aims to evaluate perceived lifetime stress, perceived stress during pregnancy, chronic hypertension, and their joint association with preeclampsia risk. This study includes 4314 women who delivered a singleton live birth at the Boston Medical Center from October 1998 through February 2008. Chronic hypertension was defined as hypertension diagnosed ...
Wakeel Fathima - - 2013
Stress during pregnancy is a salient risk factor for adverse obstetric outcomes. Personal capital during pregnancy, defined as internal and social resources that help women cope with or decrease their exposure to stress, may reduce the risk of poor obstetric outcomes. Using data from the 2007 Los Angeles Mommy and ...
Zhu Peng - - 2013
To investigate the time-specific effect of maternal exposure to prenatal stressful life events (SLEs) on gestational weight gain (GWG) and to determine whether pre-pregnancy body mass index (BMI) modifies the effect. Between March and November 2008, data were collected from 1800 pregnant women who received prenatal check-ups in Hefei, China, ...
Reynolds Rebecca M - - 2013
The developing foetus makes adaptations to an adverse in utero environment which may lead to permanent changes in structure and physiology, thus 'programming' the foetus to risk of ill health in later life. Epidemiological studies have shown associations between low birth weight, a surrogate marker of an adverse intrauterine environment, ...
Nelson Deborah B - - 2013
Abstract Background: Unintended pregnancy (UP) is common, particularly among women exposed to violence, and it is linked to adverse maternal and child outcomes. This study investigated the potential role of current depressive symptoms, social support, and psychosocial stress in moderating the association between violence exposure and UP. Methods: Pregnant women, ...
Banerjee Poulomi - - 2013
Metformin is not only a widely used oral antidiabetic drug, which acts as an insulin sensitizer and suppressor of hepatic gluconeogenesis, but it also exhibits antitumor properties. Besides, it has been utilised in the treatment of Polycystic Ovary Syndrome (PCOS) for infertile women with glucose intolerance and as a component ...
Anai Takanobu - - 2013
Transient osteoporosis of the hip (TOH) in pregnancy is characterized by severe pain in unilateral or bilateral hips and has been diagnosed as localized osteopenia. However, we evaluated a case of unilateral TOH with generalized profound osteoporosis involving both the hips and the lumbar vertebrae by dual-energy X-ray absorptiometry. The ...
Ghaemmaghami Pearl - - 2013
The underlying biological mechanism of prenatal stress in humans is poorly understood, but maternal cortisol (F) excess seems to play an important role. In pregnant rats, acute stress causes an up-regulation of placental 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2), an enzyme present throughout the body (e.g., placenta, salivary glands) that inactivates ...
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