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Sales F A FA AgResearch, Grasslands Research Centre, Palmerston North, New Zealand Gravida: National Research Centre for Growth and Development, Auckland, New Zealand Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand Instituto de Investigaciones Agropecuarias, Centro Regional Kampenaike, Punta Arenas, - - 2014
The objective of this study was to determine the association between intracellular free AA (FAA) profiles in skeletal muscle with muscle growth in twin and singleton fetuses in late pregnancy and at weaning, under an ad libitum feeding regime of the dam. Plasma from singleton- (n = 9) and twin-bearing ...
Kampman M A M MA From the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands; The Netherlands Heart Institute (ICIN), Utrecht, The - - 2014
To investigate the existing evidence for a link between maternal cardiac function, abnormal utero-placental flow and poor perinatal outcome in women with and without known cardiac disease. The Pubmed and Embase databases were systematically searched for studies relating cardiac functional parameters, uteroplacental flows and pregnancy outcome in women with preexistent ...
Montufar-Rueda Carlos C *Complejo Hospitalario, Caja de Seguro Social, Panama City, Panama †Department of Obstetrics, Gynecology and Reproductive Medicine, Division of Maternal-Fetal Medicine, University of Texas Health Science Center, Houston, - - 2014
Cardiac arrest is a rare event during pregnancy. The pregnant population represents a unique subset of cardiac arrest victims. Not only are there unique causes of circulatory collapse during the pregnant state, but the physiological modifications to the maternal physiology during pregnancy require specific modifications to the standard management of ...
Cox Phillip M PM West Midlands Perinatal Pathology, Birmingham Womens NHSFT, Birmingham, - - 2014
Chronic twin-to-twin transfusion syndrome (cTTTS) complicates 4-35% of monochorionic diamniotic (MCDA) twin pregnancies and untreated carries a mortality of some 80%, with significant neurological disability in 30-35% of survivors. MCDA twin pregnancies are usually closely monitored for cTTTS, which is identified by discordant growth of the twins with polyhydramnios and ...
Coleman Alan A Cincinnati Fetal Center, Center for Fetal Cellular and Molecular Therapy, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United - - 2014
Abstract Objective To measure amniotic fluid leptin levels in fetuses with twin-twin transfusion syndrome (TTTS) with and without placental insufficiency (PI) and determine its usefulness as a biomarker of PI. Study Design A retrospective case control study of TTTS stage III patients from 2009-2011 was conducted. Cases were pregnancies with ...
Premru-Srsen Tanja T Department of Perinatology, Division of Gynecology, University Medical Center - - 2014
Abstract Objective: The aim of this study was to establish early pregnancy risk indicators for spontaneous twin very preterm birth. Methods: We conducted a retrospective observational population-based study. Twenty-one potential early pregnancy risk factors were analyzed using multivariable logistic regression to determine which of them was independently associated with spontaneous ...
Melamed Nir N Helen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, - - 2014
To assess the accuracy and to determine the optimal threshold of sonographic cervical length (CL) for the prediction of preterm delivery (PTD) in women with twin pregnancies presenting with threatened preterm labor (PTL). A retrospective study of women with twin pregnancies who presented with threatened PTL and underwent sonographic measurement ...
Segal Nancy L NL Department of Psychology,California State - - 2014
The International Society for Twin Studies has lost a valued friend and colleague. Dr Louis Keith, Emeritus Professor of Obstetrics and Gynecology at Northwestern University, in Chicago, passed away on Sunday, July 6, 2014. His life and work with twins will be acknowledged at the November 2014 International Twin Congress ...
- - 2014
THIS IS a true story of two siblings diagnosed with hypothyroidism that recalls the appearance and behaviour changes associated with this condition, treatment and follow up.
Allaf M Baraa MB Department of Obstetrics and Gynecology, Stony Brook Medicine, Stony Brook, New York USA (M.B.A., P.O., R.F.); Department of Obstetrics and Gynecology, Winthrop University Hospital, Mineola, New York USA (M.B.A., A.M.V., M.R.C.); Department of Obstetrics and Gynecology, University of Connecticut, Farmington, Connecticut USA (W.A.C., S.F.R., Al.A.S.); Department of Obstetrics and Gynecology, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas USA (S.H., P.J., R.R., H.S.-H., B.S., M.A.B., Al.A.S.); Department of Obstetrics and Gynecology, George Washington University, Washington, DC USA (Am.A.S.); Sidra Medical and Research Center, Doha, Qatar (P.O.); Hartford Hospital, Hartford, Connecticut USA (R.F., A.B.); Department of Obstetrics and Gynecology, Maine Medical Center, Portland, Maine USA (J.W., G.M.); Department of Obstetrics and Gynecology, Baystate Medical Center, Springfield, Massachusetts USA (S.F.R.); Department of Obstetrics and Gynecology, University of Illinois, Chicago, Illinois, USA (S.F.R.); Department of Obstetrics and Gynecology, University of Vermont, Burlington, Vermont USA (M.M., S.D.); Department of Obstetrics and Gynecology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire USA (J.J.); and Department of Preventive Medicine, University of Southern California, Los Angeles, California USA - - 2014
To determine whether intertwin discordant abdominal circumference, femur length, head circumference, and estimated fetal weight sonographic measurements in early second-trimester monochorionic diamniotic twins predict adverse obstetric and neonatal outcomes. We conducted a multicenter retrospective cohort study involving 9 regional perinatal centers in the United States. We examined the records of ...
Maisonneuve Emeline E Department of Obstetrics and Gynaecology and CHU Sainte-Justine, Université de Montréal and Research Centre, Montreal, Quebec, - - 2014
Abstract Objective: Intrauterine growth restriction (IUGR) and prenatal exposure to oxidative stress are thought to lead to increased risks of cardiovascular disease later in life. The objective of the present study was to document whether cord blood oxidative stress biomarkers vary with the severity of IUGR and of vascular disease ...
Pettit K E KE Department of Reproductive Medicine, University of California, San Diego Health System, San Diego, CA, - - 2014
Objective:To determine whether inadequate gestational weight gain in the second trimester in twin pregnancies is associated with an increased risk of preterm birth (PTB) at <32 weeks.Study Design:Retrospective cohort study including 489 twin pregnancies delivered between 2001 and 2013. Rates of weight gain at different gestational ages were compared with ...
Peyvandi Shabnam S Division of Cardiology, Department of Pediatrics; The Fetal Treatment Center, all at the University of California San Francisco Benioff Children's Hospital, San Francisco, Calif., USA, - - 2014
Twin reversed arterial perfusion (TRAP) sequence affects 1% of monochorionic (MC) pregnancies and is caused by abnormal vascular connections between a pump twin and an acardiac mass. The effects of abnormal vascular connections on cerebral vasculature in the pump twin are unknown. We hypothesize that abnormal cerebral vascular impedance, assessed ...
Ferguson Kelly K KK Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI, - - 2014
To investigate oxidative stress as a mechanism of preterm birth in human subjects, we examined associations between urinary biomarkers of oxidative stress measured at multiple time points during pregnancy and preterm birth. This nested case-control study included 130 mothers who delivered preterm and 352 who delivered term who were originally ...
Pierlot Caitlin M CM School of Biomedical Engineering, Dalhousie University, 5981 University Avenue, Halifax, NS, B3H 3J5, - - 2014
Pregnancy produces rapid, non-pathological volume-overload in the maternal circulation due to the demands of the growing fetus. Using a bovine model for human pregnancy, previous work in our laboratory has shown remarkable pregnancy-induced changes in leaflet size and mechanics of the mitral valve. The present study sought to relate these ...
Rossi A Cristina AC Department of Obstetrics and Gynecology, University of Bari, Bari, - - 2014
To analyze outcomes of monochorionic twins with twin anemia-polycythemia sequence (TAPS). PubMed, EMBASE, Medline, and reference list. We included reports of TAPS defined prenatally with abnormal Doppler studies of middle cerebral artery and normal amniotic fluid volume which reported data as proportional rates. Abstracted outcomes were postnatal hemoglobin levels, postnatal ...
Pereira Ana C AC Unit of Molecular Mechanisms of Disease (CISA) and Chemical and Biomolecular Sciences, School of Allied Health Sciences, Polytechnic Institute of Porto (ESTSP-IPP), Porto, - - 2014
Oxidative stress designates the state of imbalance between reactive oxygen species (ROS) production and antioxidant levels. In a healthy placenta, there is an increase in ROS production, due to formation of new tissues and inherent metabolism, but this is balanced by higher levels of antioxidants. However, this balance is lost ...
Kacerovsky Marian M Biomedical Research Center, University Hospital Hradec Kralove, Czech - - 2014
Abstract Objective: To determine the cervical and vaginal fluid soluble Toll-like receptor-2 (sTLR2) levels in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) and their correlation to microbial invasion of the amniotic cavity (MIAC) and/or histological chorioamnionitis (HCA). Methods: Sixty-eight women with singleton pregnancies complicated by PPROM were included ...
Raicevic S S Clinic of Gynecology and Obstetrics, Clinical Centre of Montenegro, Podgorica, - - 2014
Fetal distress represents a pathophysiological condition in which oxygen is not available to the fetus in sufficient quantities. In cases of glucose 6-phosphate dehydrogenase (G6PD) deficiency, under conditions of oxidative stress, the residual G6PD and complimentary antioxidant mechanisms may become insufficient to neutralize the large amounts of ROS and to ...
Lee Chulhee C Department of Economics, Seoul National University, Seoul, South Korea. Electronic address: - - 2014
The evidence that demonstrates the negative effects of maternal psychological stress during pregnancy on a wide variety of offspring outcomes is growing. Animal studies suggest that negative influences of maternal stress during pregnancy persist across multiple generations, but the direct evidence to confirm that the effect is present among human ...
McDonald Sheila W SW Department of Paediatrics, University of Calgary, Calgary, AB, Canada, - - 2014
Preterm birth constitutes a significant international public health issue, with implications for child and family well-being. High levels of psychosocial stress and negative affect before and during pregnancy are contributing factors to shortened gestation and preterm birth. We developed a cumulative psychosocial stress variable and examined its association with early ...
Christian Lisa M LM Department of Psychiatry, The Ohio State University Wexner Medical Center, Columbus, Ohio, 43210, USA; The Institute for Behavioral Medicine Research, The Ohio State University Wexner Medical Center; Department of Psychology, The Ohio State University, Columbus, Ohio, 43210, USA; Department of Obstetrics and Gynecology, The Ohio State University Wexner Medical Center, Columbus, Ohio, 43210, USA. Electronic address: - - 2014
There is a substantial body of literature linking psychological stress to adverse pregnancy outcomes, particularly preterm birth. Comparatively few studies have examined potential biological mechanisms explaining these associations. Attention to inflammatory processes is warranted. The current paper describes emerging studies demonstrating that, as in nonpregnant humans and animals, psychological stress ...
Hux Vanessa J VJ Vanderbilt University School of Medicine, Nashville, TN, USA, - - 2014
Preeclampsia is a multisystemic disorder of pregnancy associated with maternal and fetal complications as well as later-life cardiovascular disease. Its exact cause is not known. We developed a pregnancy-specific multisystem index score of physiologic risk and chronic stress, allostatic load (AL), early in pregnancy. Our objective was to determine whether ...
Slimani Ouafae - - 2014
Pregnancy-related compressive myelopathy secondary to vertebral hemangioma is a rare occurrence and its treatment antepartum is rare. A 19-year-old North African woman in her 38th week of pregnancy presented with paraplegia that progressed within 2 days after a rapidly progressive weakness of her lower limbs. Magnetic resonance imaging studies showed ...
Silveira M L ML Division of Biostatistics & Epidemiology, Department of Public Health, School of Public Health & Health Sciences, University of Massachusetts, Amherst, MA, - - 2014
Prior literature suggests a positive association between psychosocial stress and the risk of diabetes in non-pregnant populations, but studies during pregnancy are sparse. We evaluated the relationship between stress and glucose intolerance among 1115 Hispanic (predominantly Puerto Rican) prenatal care patients in Proyecto Buena Salud, a prospective cohort study in Western ...
Xiao Songshu - - 2014
Intrauterine fetal bone retention is a rare complication and the bony fragments probably work like an intrauterine contraceptive device resulting in secondary infertility. Among the scarcely reported cases in the literature, there was no report described the retention of a large number of fetal bones with nearly intact morphology. The ...
Valdez Susana R SR Laboratorio de Reproducción y Lactancia, IMBECU-CONICET, Mendoza, Argentina; Instituto de Ciencias Básicas, Universidad Nacional de Cuyo, Mendoza, - - 2014
The opioid system modulates prolactin release during late pregnancy. Its role and the participation of ovarian hormones in this modulation are explored in ether stress-induced prolactin release. Estrous, 3-day and 19-day pregnant rats were used. We administered the antagonist mifepristone (Mp) and tamoxifen to evaluate progesterone and estradiol action in ...
Beijers Roseriet R Department of Developmental Psychology, Behavioral Science Institute, Radboud University Nijmegen, P.O. Box 9104, 6500 HE, Nijmegen, The Netherlands, - - 2014
Accumulating evidence from preclinical and clinical studies indicates that maternal psychosocial stress and anxiety during pregnancy adversely affect child outcomes. However, knowledge on the possible mechanisms underlying these relations is limited. In the present paper, we review the most often proposed mechanism, namely that involving the HPA axis and cortisol, ...
Palagini Laura L Department of Clinical Experimental Medicine, Psychiatric Unit, University of Pisa, School of Medicine, Pisa, Italy. Electronic address: - - 2014
Short sleep duration, poor sleep quality, and insomnia frequently characterize sleep in pregnancy during all three trimesters. We aimed: (i) to review the clinical evidence of the association between conditions of sleep loss during pregnancy and adverse pregnancy outcomes; and (ii) to discuss the potential pathophysiological mechanisms that may be ...
Ferguson Kelly - - 2014
Phthalate exposure during pregnancy has been linked to adverse birth outcomes such as preterm birth, and inflammation and oxidative stress may mediate these relationships. In a prospective cohort study of pregnant women recruited early in gestation in Northern Puerto Rico, we investigated the associations between urinary phthalate metabolites and biomarkers ...
Lim Robert R Harvard School of Public - - 2014
We sought to test experimentally whether maternal stress can promote susceptibility to development of asthma-like allergic airways disease in offspring. Normal pregnant mice (day 15) were subjected to a single restraint stress exposure. We subsequently tested their offspring for the development of airway hyperreactivity (AHR) and allergic airway inflammation (AI), ...
Thomas Melanie M Department of Psychiatry, University of California, San Francisco, California. Electronic address: - - 2014
Prepregnancy body mass index and excessive gestational weight gain (GWG) are associated with adverse maternal and infant outcomes. Because stress contributes to obesity and eating behaviors, stress reduction interventions during pregnancy may be a novel way to influence GWG, positively affect maternal and infant outcomes, and address the obesity epidemic ...
Shishehgar Sara S Centre for Cardiovascular & Chronic Care, Faculty of Health, UTS, Tehran, Iran. - - 2014
Stress during pregnancy can result in critical negative outcomes on the mother, the fetus, the newborn, the child and even the adolescent. Quality of life has been recognized as a predictor of stress amongst pregnant women. The first aim of this study was to investigate the role of quality of ...
Shishehgar Sara S Centre for Cardiovascular & Chronic Care, Faculty of Health, UTS, Australia. - - 2014
Stress during pregnancy can have serious adverse outcomes on the mother, the fetus, newborn, children and even adolescents. Socioeconomic status has been recognized as a predictor of stress amongst pregnant women. The first aim of this study was to investigate the role of socioeconomic status in pregnancy stress rates. The ...
Graignic-Philippe R R Pôle Hospitalo-Universitaire de Psychiatrie de l'Enfant et de l'Adolescent de Rennes, Université de Rennes 1 et Centre Hospitalier Guillaume Régnier, Rennes, France. Electronic address: - - 2014
Many studies have examined effects of prenatal stress on pregnancy and fetal development, especially on prematurity and birthweight, and more recently long-term effects on child behavioral and emotional development. These studies are reviewed and their limitations are discussed with regard to definitions (including the concepts of stress and anxiety), stress ...
Amaliev Georgi I - - 2014
Twin-reversed arterial perfusion sequence is a rare complication of monochorionic twin pregnancy in which an anomalous acardiac fetus is hemodynamically dependent on its structurally normal "pump" twin. Early diagnosis is essential for improving perinatal prognosis for the normal twin. In this case report we present a case of TRAP sequence ...
Gervaso Francesca F Laboratory of Biological Structure Mechanics, Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milan, Italy. Electronic address: - - 2014
The umbilical cord is a conduit between the developing foetus and the placenta. In physiological conditions it contains two arteries and one vein immersed in a mucoid tissue called Wharton׳s jelly. Although the extreme importance of such a structure is fully recognized, the umbilical cord and its components have been ...
Whisner Corrie M CM Division of Nutritional Sciences, Cornell University, Ithaca, - - 2014
Few studies have examined the effect of maternal calcium intake and vitamin D status on bone health across gestation in pregnant adolescents. This study aimed to characterize maternal bone quality and determinants of bone quality change across gestation in pregnant adolescents. Healthy pregnant adolescents (n = 156; aged 13-18 y) with singleton ...
Malti N N Laboratory of Physiology, Physiopathology and Biochemistry of Nutrition, Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe, University ABOU-BEKR BELKAÏD, Tlemcen 13000, - - 2014
To determine oxidative stress markers in maternal obesity during pregnancy and to evaluate feto-placental unit interaction, especially predictors of fetal metabolic alterations. 40 obese pregnant women (prepregnancy BMI > 30 kg/m²) were compared to 50 control pregnant women. Maternal, cord blood and placenta samples were collected at delivery. Biochemical parameters (total cholesterol and ...
Thayer Zaneta M ZM Department of Anthropology, University of Colorado Denver, Denver, Colorado, - - 2014
Maternal hypothalamic pituitary adrenal-axis function regulates production of the stress hormone cortisol, which during pregnancy can cross the placenta and have lasting impacts on fetal growth and development. This article provides a preliminary test of the hypothesis that a woman's socioeconomic status (SES) predicts her cortisol during pregnancy and her ...
Young Bridget E BE *Division of Nutritional Sciences, Cornell University, Ithaca, New York, - - 2014
The purpose of the study was to identify determinants of placental vitamin D receptor (VDR) expression and placental calcium (Ca) transfer among pregnant adolescents. Placental tissue was obtained in 94 adolescents (≤18 yr) at term. In 12 of these teens, stable Ca isotopes were given intravenously ((42)Ca) and orally ((44)Ca) ...
Mano Yukio Y Departments of Pathology and Biological Responses; Gynecology and - - 2014
Molecular hydrogen (H2) scavenges hydroxyl radicals. Recently, H2 has been reported to prevent a variety of diseases associated with oxidative stress in model systems and in humans. Here, we studied the effects of H2 on rat fetal hippocampal damage by ischemia and reperfusion (IR) on day 16 of pregnancy with ...
Vidal Zendy Evelyn Olivo ZE Instituto de Salud Pública, Universidad Veracruzana, Avenida Luís Castelazo Ayala S/N, Col. Industrial Ánimas, Xalapa, Veracruz, - - 2014
Iodine is an essential element trace for the synthesis of maternal thyroid hormones needed to support normal fetal development; it also acts as an antioxidant directly or induce antioxidant enzymes indirectly. Iodine deficiency and oxidative stress are associated with pregnancy complications. This study aimed to assess the urinary iodine concentration ...
Feola Andrew A Cluster Organ Systems, Department Development and Regeneration, Faculty of Medicine, KU Leuven, Leuven, - - 2014
The vagina and surrounding structures have been shown to remodel during pregnancy. Our objective was to characterize the biomechanical properties of the vagina in the rodent model in vivo utilizing three-dimensional (3D) ultrasound. The vagina was visualized by ultrasound after distention by increasing pressures throughout pregnancy (15 and 18 days) and ...
Cole-Lewis Heather J - - 2014
Objective: There is evidence that pregnancy-specific stress is associated with preterm birth. The purpose of this study is to examine the association between change in pregnancy-specific stress over the course of pregnancy and birth outcomes (i.e., preterm birth and gestational age) in an understudied but vulnerable group using a theoretically ...
Redman C W CW The John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom. Electronic address: - - 2014
Incomplete spiral artery remodelling is the first of two stages of pre-eclampsia, typically of early onset. The second stage comprises dysregulated uteroplacental perfusion and placental oxidative stress. Oxidatively stressed syncytiotrophoblast (STB) over-secretes proteins that perturb maternal angiogenic balance and are considered to be pre-eclampsia biomarkers. We propose that, in addition ...
Cotechini Tiziana T Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada K7L - - 2014
Fetal growth restriction (FGR) and preeclampsia (PE) are often associated with abnormal maternal inflammation, deficient spiral artery (SA) remodeling, and altered uteroplacental perfusion. Here, we provide evidence of a novel mechanistic link between abnormal maternal inflammation and the development of FGR with features of PE. Using a model in which ...
Yoshida Kyoko - - 2014
The remodeling of the cervix from a rigid barrier into a compliant structure, which dilates to allow for delivery, is a critical process for a successful pregnancy. Changes in the mechanical properties of cervical tissue during remodeling are hypothesized to be related to the types of collagen crosslinks within the ...
Leuner Benedetta B Departments of Psychology and Neuroscience, The Ohio State University, Columbus, Ohio, United States of - - 2014
Postpartum depression, which affects approximately 15% of new mothers, is associated with impaired mother-infant interactions and deficits in cognitive function. Exposure to stress during pregnancy is a major risk factor for postpartum depression. However, little is known about the neural consequences of gestational stress. The medial prefrontal cortex (mPFC) is ...
Singh Sarika S Department of Pathology, Lady Hardinge Medical College, New Delhi, DL 110001, - - 2014
Gestational trophoblastic diseases (GTD) are a heterogenous group of disorders that arise from trophoblastic epithelium. They can follow molar pregnancy (50%), abortions (25%), normal pregnancy (22.5%), and ectopic pregnancy (2.5%) [Robert JK, Lora HE, Brigitte MR (ed) Blaustein Pathology of the Female Genital Tract 6th edn (Springer) pp. 1101-7]. Occurrence ...
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