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Sawant Onkar B - - 2013
BACKGROUND: Heavy alcohol consumption during pregnancy negatively impacts the physical growth of the fetus. Although the deleterious effects of alcohol exposure during late gestation on fetal brain development are well documented, little is known about the effect on fetal bone mechanical properties or the underlying mechanisms. The purpose of this ...
Quaresma Cláudia - - 2013
Objective: To present the results of the first application of the new technology - Vertebral Metrics - the analysis of the 3D position of the vertex of each spinous process in pregnant women. Material and Methods: The Vertebral Metrics was applied to women without associated pathology in four stages of ...
Nast Irina - - 2013
A growing body of literature documents associations of maternal psychosocial stress during pregnancy with fetal, infant and child behaviour and development. However, findings across studies are often inconsistent, which may in part be due to differences in stress definitions and assessments. We systematically reviewed methods applied to assess maternal psychosocial ...
M-Hyodo Hiroe - - 2013
Changes in the length and consistency of the uterine cervix during pregnancy are known to precede pre-term labor. However, cervical consistency has not been studied in depth because its objective evaluation requires special equipment. Our aim was to define a new index to evaluate cervical consistency simply and easily using ...
Toblli Jorge E - - 2013
Although oral iron preparations are widely prescribed to prevent and to treat iron deficiency anemia in pregnancy, comparative data on their effects to the mother, fetus and placenta are limited. In this study, the effects of oral iron polymaltose complex (IPC), ferrous fumarate (FF) and ferrous sulfate (FS) were compared ...
Ahsan Touhida - - 2013
Preeclampsia and eclampsia are fatal medical complications of pregnancy accounting for 20-80 % of increased maternal death in developing countries. Their aetiologies are still under investigation. Serum trace elements have been suggested to be involved in the pathogenesis of preeclampsia. Aim of this study was to address the correlation of serum ...
Aye Irving L M H - - 2013
The human placenta, in addition to its roles as a nutrient transfer and endocrine organ, functions as a selective barrier to protect the fetus against the harmful effects of exogenous and endogenous toxins. Members of the ATP-binding cassette (ABC) family of transport proteins limit the entry of xenobiotics into the ...
Razurel Chantal - - 2013
This article presents the Antenatal Perceived Stress Inventory. The originality of this scale is to assess the impact of events experienced during pregnancy on the stress perceived by mothers. Scale validation was performed using data from 150 French-speaking nulliparous mothers and collected between 36 and 39 weeks of gestation (T1), ...
Barrett Emily S ES Department of Obstetrics and Gynecology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA. - - 2013
In animal models, prenatal stress programs reproductive development in the resulting offspring, however little is known about effects in humans. Anogenital distance (AGD) is a commonly used, sexually dimorphic biomarker of prenatal androgen exposure in many species. In rodents, prenatally stressed males have shorter AGD than controls (suggesting lower prenatal ...
Witt Whitney P - - 2013
Mounting evidence from clinic and convenience samples suggests that stress is an important predictor of adverse obstetric outcomes. Using a proposed theoretical framework, this review identified and synthesized the population-based literature on the measurement of stress prior to and during pregnancy in relation to obstetric outcomes. Population-based, peer-reviewed empirical articles ...
Bourke Chase H CH Laboratory of Neuropsychopharmacology, Department of Psychiatry and Behavioral Sciences, Emory University, 101 Woodruff Circle, Suite 4000, Atlanta, GA 30322, - - 2013
A rigorously investigated model of stress and antidepressant administration during pregnancy is needed to evaluate possible effects on the mother. The objective of this study was to develop a model of clinically relevant prenatal exposure to an antidepressant and stress during pregnancy to evaluate the effects on maternal care behavior. ...
Yilmaz S D - - 2013
OBJECTIVE: to evaluate how a history of pregnancy loss in the perinatal period (from 20 weeks of gestation to seven days post partum) affects women during subsequent pregnancies. DESIGN: cross-sectional, descriptive study. SETTING: Istanbul Medical School, Istanbul University between January and October 2009. PARTICIPANTS: 128 pregnant women with a history ...
Briana Despina D - - 2013
Abstract Objective: To investigate possible associations of the novel adipocytokines resistin, apelin and visfatin (implicated in the complex control of bone biology) with several biochemical determinants of bone turnover in maternal blood from normal pregnancies and pregnancies complicated by gestational hypertensive disorders (preeclampsia or pregnancy-induced hypertension). Methods: Circulating maternal concentrations ...
Entringer Sonja - - 2013
PURPOSE OF REVIEW: To summarize recent conceptual frameworks and empirical findings addressing the role of prenatal stress and stress biology in the context of fetal programming of metabolic function and obesity risk. RECENT FINDINGS: The link between stress exposure and adverse health outcomes is well established. Growing evidence from animal ...
Cardwell Michael S - - 2013
Stress-induced pregnancy complications represent a significant cause of maternal and perinatal morbidity and mortality due to preterm labor, low-birth-weight babies, pregnancy-induced hypertension, and neuropsychological developmental delays of affected offspring. Psychosocial factors such as socioeconomic status, work status, marital status, level of education, access to prenatal care, substance abuse, ethnicity, cultural ...
Hilali Nese - - 2013
To determine the oxidative status and serum prolidase activity in tubal ectopic pregnancy and to see if there was any association between them. MATHODS: The cross-sectional study was conducted during 2009 and 2010 at the Departments of Obstetrics and Gynaecology and Clinical Biochemistry under the Faculty of Medicine, Harran University, ...
Huang Yunxia - - 2013
Round ligament varicosities associated with uterine varicosities are rare during pregnancy. We report the case of a pregnant woman with a painful mass in her left groin at 32 weeks' gestation. Ultrasound revealed multiple distended veins within the left round ligament and over the uterus. The patient was treated by ...
Holloway Terrell - - 2013
It has been suggested that severe adverse life events during pregnancy increase the risk of schizophrenia in the offspring. The serotonin 5-HT(2A) and the metabotropic glutamate 2 (mGlu2) receptors both have been the target of considerable attention regarding schizophrenia and antipsychotic drug development. We tested the effects of maternal variable ...
Chen Yu-Chieh - - 2013
Compromised pregnancies such as those associated with gestational diabetes mellitus, intrauterine growth retardation, preeclampsia, maternal undernutrition, and maternal stress may negatively affect fetal development. Such pregnancies may induce oxidative stress to the fetus and alter fetal development through the epigenetic process that may affect development at a later stage. Melatonin ...
Golbidi Saeid - - 2013
Gestational diabetes mellitus (GDM) is defined as glucose intolerance first diagnosed during pregnancy. This condition shares same array of underlying abnormalities as occurs in diabetes outside of pregnancy, for example, genetic and environmental causes. However, the role of a sedentary lifestyle and/or excess energy intake is more prominent in GDM. ...
Huth-Bocks Alissa C - - 2013
Abstract Women experience remarkably high rates of relational trauma including childhood abuse and neglect and intimate partner violence (IPV) during adulthood, and the childbearing years are no exception. The meaning of past and current relational trauma perpetrated by primary caregivers and significant others may be unique during pregnancy, in particular, ...
Dey Madhusudan - - 2013
Pre-eclampsia is one of the leading causes of high rates of maternal and perinatal mortality and morbidity. Pathophysiology of pre-eclampsia is still obscure. Currently, there are no screening tests for pre-eclampsia that are reliable, valid, and economical. Parameters of oxidative stress could be early markers of endothelial dysfunction that predates ...
Wynne-Edwards Katherine E - - 2013
Fetal stress is relevant to newborn outcomes. Corticosterone is rarely quantified in human clinical endocrinology and is found at much lower concentrations than cortisol. However, fetal corticosterone is a candidate hormone as a fetal stress signal. Test the hypothesis that preferential fetal corticosterone synthesis occurs in response to fetal intra-partum ...
Qiu Chunfang - - 2013
Available evidence supports the role of reactive oxygen species in the pathogenesis of placental insufficiency, gestational diabetes mellitus (GDM), and other pregnancy complications. Abnormal placental mitochondrial function resulting from reactive oxygen species may also be an important precedent of adverse perinatal outcomes. We investigated the association of placental oxidative stress ...
Kaya S - - 2013
Background: The placenta is the major source of oxidative stress in normal human pregnancy. The placental tissue is typically functional in postterm pregnancies. We hypothesized that such pregnancies experience deteriorating oxidative balance and increasing oxidative stress. In this case-control study, our aim was to investigate the oxidative status in postterm ...
Grieger Jessica A - - 2013
The complication of asthma during pregnancy is associated with a number of poor outcomes for the mother and fetus. This may be partially driven by increased oxidative stress induced by the combination of asthma and pregnancy. Asthma is a chronic inflammatory disease of the airways associated with systemic inflammation and ...
Claridge Amy M - - 2013
This study examined demographic characteristics, available resources, and mental health outcomes of women who did and did not consider abortion in pregnancy. Using data collected between 1998 and 2000 from 2,937 mothers recruited for the Fragile Families and Child Well-Being Study, this study examined whether women who did and did ...
D'Souza V - - 2013
During pregnancy, oxidative stress has been implicated in the pathophysiology of preeclampsia and preterm birth leading to poor birth outcome. Hyperhomocysteinemia caused as a consequence of altered micronutrients like folic acid and vitamin B12 is associated with increased production of reactive oxygen species that generate oxidative stress. These micronutrients are ...
Klaus Teresa - - 2012
Stress experienced during pregnancy can have persistent impact on the female's physiology and behaviour not only during but even beyond pregnancy. The present study aimed to evaluate such long-term effects of stress in terms of repeated strobe light exposure during early to mid gestation on behavioural aspects of mothering activities ...
Thomson Murray - - 2012
In response to stress, the hypothalamus releases cortiticotropin releasing hormone (CRH) that travels to the anterior pituitary, where it stimulates the release of adrenocorticotropic hormone (ACTH). ACTH travels to the adrenal cortex, where it stimulates the release of cortisol and other steroids that liberate energy stores to cope with the ...
Ernst Linda M - - 2012
Objective To estimate the association between biomarkers of chronic stress during pregnancy and chronic placental inflammation.Study Design African-American and Caucasian pregnant women were recruited between May 2008 and July 2009. Blood samples were collected between 14 and 226/7 weeks and between 28 and 326/7 weeks of gestation. Samples were analyzed for serum ...
Escobar Javier - - 2012
Background: In spite of improvement in obstetrical care, pregnancy in women with type 1 diabetes mellitus is associated with increased perinatal morbidity and mortality. Hyperglycemia during pregnancy causes excessive fetal growth and chronic fetal hypoxia as reflected in increased erythropoietin (EPO) levels in amniotic fluid (AF). Objectives: We hypothesized that ...
Mparmpakas D - - 2013
Pregnancy is associated with major physiological and future psychosocial changes, and maternal adaptation to these changes is crucial for normal foetal development. Psychological stress in pregnancy predicts an earlier birth and lower birth weight. Pregnancy-specific stress contributes directly to preterm delivery. The importance of nutrition and exercise during pregnancy with ...
Loy See-Ling - - 2012
OBJECTIVE: This study aimed to evaluate changes in maternal adiposity and lipid profile and to correlate these parameters with Deoxyribonucleic acid (DNA) damage and total antioxidant capacity (TAC) levels among pregnant women. METHOD: This was a longitudinal study which took place in Kelantan state, Malaysia. Fasting blood samples of 159 ...
Painter Rebecca C - - 2012
There is a growing body of evidence suggesting that events during prenatal life can have long-lasting effects on development and adult health. Stress during pregnancy is common and has been linked to increased incidence of a range of affective and behavioral outcomes in the offspring in later life and also ...
Entringer Sonja S Department of Pediatrics, University of California, Irvine, School of Medicine, Irvine, CA 92697, - - 2013
In adults, one of the major determinants of leukocyte telomere length (LTL), a predictor of age-related diseases and mortality, is cumulative psychosocial stress exposure. More recently we reported that exposure to maternal psychosocial stress during intrauterine life is associated with LTL in young adulthood. The objective of the present study ...
Seo Jin-Hee - - 2012
Post‑traumatic stress disorder (PTSD) is an anxiety disorder triggered by life‑threatening events that cause intense fear. Exercise is known to have protective effects on neuropsychiatric diseases. The present study investigated whether treadmill exercise during pregnancy reduced or alleviated symptoms of PTSD in maternal rats. To induce predator stress in pregnant ...
House Michael - - 2012
Preterm birth affects over 12% of all pregnancies in the United States for an annual healthcare cost of $26 billion. Preterm birth is a multifactorial disorder but cervical abnormalities are a prominent feature in many patients. Women with a short cervix are known to be at increased risk for preterm ...
Hernandez-Andrade Edgar - - 2012
Objective. To evaluate cervical stiffness during pregnancy using ultrasound-derived elastography, a method used to estimate the average tissue displacement (strain) on a defined region of interest when oscillatory compression is applied. Methods. Strain was calculated in two regions of interest, the endocervical canal and the entire cervix, from three anatomical ...
Saphier Oshra - - 2012
PURPOSE: The production of reactive oxygen substances plays an important regulatory role in many physiologic reproductive processes. Excessive production may lead to oxidative stress (OS), and bring about pregnancy disorders. Growing evidence indicates that OS plays a major role in the pathophysiology of complications such as early pregnancy loss, placental ...
Schuurmans Carol - - 2012
A simple internet search of "maternal stress and pregnancy" turns up hundreds of hits explaining that an adverse intrauterine environment can affect fetal development and potentially lead to various learning, behavioral, and mood disorders in childhood, as well as complex diseases such as obesity and cardiovascular conditions later in life. ...
Akhter Tansim - - 2012
The vascular effects of normal pregnancy were investigated by estimating the intima and media thicknesses of the common carotid artery separately using 22MHz ultrasound (Collagenoson, Meudt, Germany) in 57 healthy women with normal pregnancies and pregnancy outcomes, in all three trimesters and at one year postpartum. A thick intima, thin ...
Kirkham Mavis - - 2012
The interactions of the hormones of pregnancy, labour and birth are complex and subtle and their effects are far reaching. Within these complex interactions beta endorphin (beta-end) has a key balancing function, being a hormone of relationship and a stress hormone. As well as helping the mother cope with labour, ...
Kocaöz Semra - - 2012
Objective: The aim of this study was to determine the role of pelvic floor muscle exercises (PFME) in the prevention of stress urinary incontinence (SUI) during pregnancy and the postpartum period. Methods: A total of 102 women was included in the study. Data, collected through forms, included characteristics of the ...
Nakatsukasa Yoko - - 2013
This study examined the clinical and biological importance of thioredoxin-1, a redox-active defensive protein that controls multiple biological functions, in pregnant women. We measured serum concentrations of thioredoxin-1, total hydroperoxides, and redox potential in 60 pregnant women at the early third trimester: gestational age of 27-29 weeks. The thioredoxin-1 concentration ...
Zhu Peng P Department of Maternal and Child Health, Anhui Medical University, and Department of Gynecology and Obstetrics, Hefei Maternal and Child Health Hospital, Hefei, - - 2013
Many perinatal stressors, including high prepregnancy body mass index, preterm birth, and cesarean section, increase the risk for short breastfeeding duration. Few studies, however, have investigated the mechanism in the relationship between perinatal determinants and breastfeeding duration. This study aimed to test the hypothesis that delayed onset of lactation (OL) ...
Fink Nadine S - - 2012
Previous studies have reported associations between maternal stress during pregnancy and obstetric outcomes as well as fetal development and neonatal adaptation. These findings highlight the importance of identifying pregnant women who experience severe stress and the need for interventions that commence early in pregnancy. The aim of this study was ...
Deepa Damayanthi - - 2012
Oxidative stress can be a final common pathway for AED-induced teratogenesis. To compare the oxidative stress of women with epilepsy (WWE) and unfavorable pregnancy outcome (fetal malformation or spontaneous abortion - group EM) with that of WWE with normal pregnancy outcome (group ENM) and healthy women with normal pregnancy outcome ...
Chung Sung Suk - - 2012
The objective of this study was to propose the post-partum blues (PPB) model and to estimate the effects of self-esteem, social support, antenatal depression, and stressful events during pregnancy on PPB. Data were collected from 249 women post-partum during their stay in the maternity units of three hospitals in Korea ...
Yang Pei-Yin - - 2012
To evaluate the normal range of the fetal nasal bone length (NBL) in Taiwanese women using three-dimensional (3D) ultrasound, and compare the NBL of normal fetuses with Down syndrome to determine its significance in screening for trisomy 21. A total of 102 consecutive fetuses and another 7 fetuses with trisomy ...
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