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Roellig Kathleen - - 2010
The European brown hare is one species in which reproduction appears to be particularly complex. Therefore, we studied the reproductive tract and prenatal development using high-resolution ultrasound of 159 pregnancies in 45 captive female hares. Consecutive examination of live hares was particularly useful in evaluating the very early stages of ...
Satué K - - 2010
In order to investigate the effect of pregnancy on equine hematological profile, venous blood samples were taken from 44 Carthusian broodmares every two weeks during pregnancy, divided into three periods: I (conception to 110 days), II (111-220 days) and III (222 days to delivery). Routine hematological analysis was performed. Packed ...
Skowronski Mariusz T - - 2010
Aquaporins (AQPs) are a family of membrane channel proteins that facilitate bulk water transport. To date, 11 isoforms of AQPs have been reported to be expressed in the female and male reproductive systems. The purpose of our study was to determine the localization and quantitative changes in the expression of ...
Li Lei - - 2010
Adrenomedullin (ADM), a novel vasorelaxant peptide, was found in human/rat ovaries and uteri. Plasma ADM level increases in pregnant women and pregnant rats. The gene expression levels of Adm and its receptor components - Crlr, Ramp1, Ramp2 and Ramp3, the ADM peptide concentration and localization in the rat female reproductive ...
Kandiel Mohamed M M - - 2010
The current study was performed to follow up the circulating hormonal changes and to correlate the findings with the physiological activity of the corpus luteum (CL) and placenta during pregnancy in goats. Blood samples were collected weekly from five goats during pregnancy for measuring steroid and protein hormones. A gradual ...
Blitek A - - 2010
This study was conducted to evaluate the effect of estrus induction with gonadotropins on endometrial and conceptus expression of HoxA10, transforming growth factor (TGF) beta1, leukemia inhibitory factor (LIF), and prostaglandin H synthase-2 (PGHS-2) during early pregnancy in pigs. Twenty-four prepubertal gilts received 750 IU of pregnant mare serum gonadotropin ...
Siawrys G - - 2009
In this study, we examined the levels of leptin and OB-Rb protein expression in the discrete areas of the porcine hypothalamus (mediobasal hypothalamus--MBH, pre-optic area--POA, stalk median eminence--SME) during mid- and late-luteal phases of the oestrous cycle (days 10-12 and 14-16) as well as two stages of pregnancy (days 14-16 ...
Knauf Sascha - - 2009
In the wild, Alpine marmots (Marmota marmota) spend most of their time in underground burrows. Thus the observation of reproduction biology during mating season, gestation, and the early juvenile development is extremely challenging. An ultrasonographic follow-up of pregnancies in captive alpine marmots illustrates the characteristic findings of different gestational phases. ...
Ypsilantis Petros - - 2009
The purpose of the present study was to describe the technique for and findings of ultrasonographic examination of the rat uterus for diagnosis of early and midterm pregnancy. The uterus of anesthetized Wistar rats was examined between days 9 and 16 post coitum by transabdominal real-time ultrasonography by using a ...
Simonoska Rusana - - 2009
CONCLUSION: ERalpha and ERbeta are present in the inner ear and are up- and down-regulated depending on the stage of maturation, development and pregnancy, suggesting that estrogen may have an effect on the cochlea during various stages of life. No estrogen receptors (ERs) were found in the cochlea of the ...
Salman Sam - - 2010
Azithromycin (AZI) is an azalide antibiotic with antimalarial activity that is considered safe in pregnancy. To assess its pharmacokinetic properties when administered as intermittent preventive treatment in pregnancy (IPTp), two 2-g doses were given 24 h apart to 31 pregnant and 29 age-matched nonpregnant Papua New Guinean women. All subjects ...
Niinimäki M - - 2009
OBJECTIVE: The antiprogestin mifepristone is widely used for medical termination of pregnancy (TOP). Previous studies have suggested that the mechanism of mifepristone is based on its action in the endometrium and myometrium. The aim of this study was to evaluate the possible effects of mifepristone on corpus luteum activity. METHODS: ...
Guo B - - 2009
Embryo implantation is critical for the successful establishment of pregnancy. Interleukin-11 (IL-11) is essential for adequate decidualization in the mouse and human via binding to the specific IL-11 receptor alpha (IL-11Ralpha). But the expression and regulation of IL-11 and IL-11Ralpha in the canine endometrium remain unknown. The aim of this ...
De W - - 2009
The present experiment was conducted to evaluate the effects of feeding allowance level on embryonic survival, uterine development and reproductive hormone secretion in early gestation gilts. A total of 54 F1 crosses of Landrace x Large white gilts were randomly allocated to three treatment groups of high (H, 2 x ...
Kurusu Shiro - - 2009
The nature of the structural regression of the corpus luteum of pregnancy (PCL) was investigated in rats from day 19 of pregnancy (PRG19) through day 6 postpartum (PP6). A pre-partum decrease in tissue weight of the PCL during the last 4 days of pregnancy was apparent (nearly a 40% decrease) ...
Simmons Rebecca M - - 2010
Establishment of pregnancy in ruminants requires conceptus elongation and production of interferon tau (IFNT), the pregnancy recognition signal that maintains the corpus luteum and progesterone (P4) secretion. The enzymes hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1) and HSD11B2 catalyze the interconversion of inactive cortisone and active cortisol, which is a biologically active ...
Assis Neto A C - - 2009
The aim of this study was to perform a morphological characterization of the initial bovine placental development, between 20 and 70 days post-insemination (p.i.), with emphasis on the differentiation of the allantois and amnion. After collection, the conceptuses were dissected, macroscopically measured and photographically documented. The extraembryonic membranes were cut ...
Samangaya Rebekah A RA Maternal & Fetal Health Research Centre, St Mary's Hospital, Manchester, United Kingdom. - - 2009
To determine if the phosphodiesterase type 5 inhibitor sildenafil prolongs pregnancy in women with preeclampsia. Women with preeclampsia at gestational ages 24-34 weeks were recruited from nine hospitals in the UK, and randomly assigned to sildenafil citrate or placebo. Medication was increased every 3 days from 20 mg three times ...
Rozance Paul J - - 2009
Protein supplementation during human pregnancy does not improve fetal growth and may increase small-for-gestational-age birth rates and mortality. To define possible mechanisms, sheep with twin pregnancies were infused with amino acids (AA group, n = 7) or saline (C group, n = 4) for 4 days during late gestation. In ...
Kusuda Satoshi - - 2009
Studies on the reproductive endocrinology of koalas have been performed mainly by using blood samples; however, in practice it is difficult to collect blood periodically because koalas are easily stressed. The purposes of the present study were to establish a noninvasive endocrine monitoring technique and to investigate the reproductive physiology ...
Tsutsui T - - 2009
Plasma progesterone (P(4)) concentrations are maintained in pregnant cats until parturition, but become low in pseudopregnant cats 40-45 days after infertile mating. This difference in P(4) concentrations is considered to be due to P(4) secretion by the placenta of pregnant cats. Therefore, to clarify these points, we performed ovariectomy (OVX) ...
Bergfelt Don R - - 2010
The primary objectives of this study were to validate a canine relaxin RIA for use in otariids and phocids and consider practical applications. For 6 captive Northern fur seal females, serum samples were grouped and examined according to pregnancy (n=13), post-partum (n=8) and non-pregnancy (n=6), and, for 2 captive Northern ...
Ratnasooriya Wanigasekera D - - 2009
The aim of this study was to demonstrate the potential effects of black tea brew of Camellia sinensis using Sri Lankan high grown dust grade no. 1 tea on pregnancy outcome of rats when exposed during early (days 1-7), mid (days 8-14) and late (days 15-21) pregnancy of rats. Different ...
Corson A M - - 2009
Women who were themselves small-for-gestational age (SGA) are at a greater risk of adulthood diseases such as non-insulin-dependent diabetes mellitus (NIDDM), and twice at risk of having an SGA baby themselves. The aim of this study was to examine the intergenerational pig. Low (L) and normal (N) birth weight female ...
McGuane Jonathan T - - 2009
In this paper, the hemodynamic changes of normal pregnancy are reviewed and the underlying hormonal and molecular mechanisms are discussed. Among other findings related to these phenomena, our previous work has demonstrated the importance of relaxin in systemic and renal vascular as well as osmoregulatory changes during gestation. These findings ...
Fields Phillip - - 2009
On day 18 of pregnancy, conceptuses were surgically removed in order that rabbits would be left with seven, five, three, or one conceptus. During pregnancy, blood concentrations of relaxin were determined by radioimmunoassay. There was no difference between relaxin concentrations in rabbits carrying one versus seven conceptuses. The results indicate ...
Steinetz B - - 2009
The human population explosion has pushed many mammalian wildlife species to the brink of extinction. Conservationists are increasingly turning to captive breeding as a means of preserving the gene pool. We previously reported that serum immunoactive relaxin provided a reliable means of distinguishing between true and pseudopregnancy in domestic dogs, ...
Goldsmith Laura T LT Department of Obstetrics, Gynecology and Women's Health, New Jersey Medical School of UMDNJ, Newark, New Jersey 07103, USA. - - 2009
Relaxin has beneficial effects upon the endometrium which are responsible for establishment of pregnancy. We have demonstrated that relaxin stimulates endometrial decidualization, the structural and biochemical changes in endometrial parenchymal cells, and the accompanying angiogenesis, modulation of matrix metalloproteinase activity, and increased concentrations in local immune cells which are required ...
Shaw Jordan - - 2009
Parabens, a class of preservatives routinely added to cosmetics, pharmaceuticals, and foods, have estrogenic properties. Given that intrauterine implantation of fertilized ova in inseminated females can be disrupted by minute levels of exogenous estrogens, we assessed the impact of parabens upon early gestation. In Experiment 1, butylparaben was administered subcutaneously ...
Aragão T P - - 2009
ETHNOPHARMACOLOGICAL RELEVANCE: Cassia occidentalis L. (Leguminosae) has long been used as natural medicine in rainforests and other tropical regions for the treatment of inflammation, fever, liver disorders, constipation, worms, fungal infections, ulcers, respiratory infections, snakebite and as a potent abortifacient. AIM OF THE STUDY: This study has investigated the effects ...
Gao Haijun - - 2009
Nitric oxide (NO) and polyamines are critical for implantation and development of conceptuses (embryo and extraembryonic membranes), but mechanisms regulating their biosynthesis in uteri and conceptuses are largely unknown. This study determined the effects of the estrous cycle, pregnancy, progesterone, and interferon tau (IFNT) on expression of NO synthases (NOS1, ...
Kaczmarek M M - - 2009
In view of the importance of vascular events observed during gestation, it was hypothesized that the VEGF-receptor system plays a critical role during early pregnancy and maternal recognition of pregnancy in pigs. This hypothesis was tested by examining the expression of the VEGF-receptor system in the porcine conceptus. Additionally, the ...
Simonoska Rusana - - 2009
Conclusion: ERalpha and ERbeta are present in the inner ear and are up- and down-regulated depending on the stage of maturation, development and pregnancy, suggesting that estrogen may have an effect on the cochlea during various stages of life. No estrogen receptors (ERs) were found in the cochlea of the ...
Xu S-Y - - 2010
Appropriate feed intake level would enhance embryo survival. This study investigated the relationship among feed intake level, embryo survival, hormone secretion and mRNA expression. Fifty-four Landrace x Yorkshire crossbred gilts were allotted to three treatment groups of high (H, 2 x maintenance), medium (M, 1.2 x maintenance) and low (L, ...
Ledgard A M - - 2009
The precise mechanism of placentation in the bovine species where a restricted trophoblast invasion occurs to form the synepitheliochorial placenta is not fully understood. This study initially investigated the conceptus-maternal interactions in the peri-attachment period by comparing the proteins present at Days 16 and 18 in uterine luminal fluid (ULF) ...
Hutton Lisa C - - 2009
Birth asphyxia is associated with disturbed development of the neonatal brain. In this study, we determined if low-dose melatonin (0.1 mg/kg/day), administered to the mother over 7 days at the end of pregnancy, could protect against the effects of birth asphyxia in a precocial species - the spiny mouse (Acomys ...
Waclawik A A Institute of Animal Reproduction and Food Research of Polish Academy of Sciences, Tuwima 10, 10-747 Olsztyn, Poland. - - 2009
Extended exposure of progesterone and conceptus estrogen influences the vascular compartment of the uterus and expression of many factors, such as prostaglandins (PGs), growth factors, extracellular matrix and adhesion molecules, cytokines and transcription factors. One of the supportive mechanisms by which the conceptus inhibits luteolysis is by changing PG synthesis ...
Johnson G A GA Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843-4458, USA. - - 2009
This review highlights information on conceptus-uterus interactions in the pig with respect to uterine gene expression in response to estrogens and interferons (IFNs) secreted from elongating conceptuses. Pig conceptuses release estrogens for pregnancy recognition, but also secrete IFNs that do not appear to be antiluteolytic. Estrogens and IFNs induce expression ...
Pallares P - - 2009
Precocity and efficiency of ultrasonography for pregnancy diagnosis and determination of litter size in mice were assessed on a total of 46 adult mice of different lines (19 BALB/c, 15 C57BL/6 and 12 CD1) from Day 4.5 after vaginal plug. Different commercial ultrasound machines and probes (linear versus sectorial; 7.5 ...
Utt M D - - 2009
The objective of this experiment was to evaluate corpus luteum blood flow (CLBF) as an early indicator of pregnancy status in bovine embryo recipients. Fifty crossbred beef cows were submitted to embryo transfer on Day 7 after estrus. On Days 7, 11, 13, 15, 17, 19, 21, 26, 33, and ...
ChruĊ›ciel M - - 2009
Stable fetal-placental blood pressure and flow are extremely important in fetal growth and development. Uncontrolled and long-standing increased or decreased vascular blood pressure in the umbilical cord (UC) affects hyperaemia or ischaemia and consequently causes fetal death. Nitric oxide (NO) is one of the most active factors controlling blood flow ...
Andronowska Aneta - - 2008
The aim of the present study was to investigate the localization and expression of NADPH-diaphorase (NADPH-d) as well as endothelial (eNOS) and inducible (iNOS) nitric oxide synthase isoforms in the porcine uterus on Days 20, 30, 40, 60, 75 and 90 of gestation. The significant increase (p<0.001) in NADPH-d reaction ...
Yanagawa Yojiro - - 2008
Information on steroid hormone receptor distribution in the uterus is essential to understand the roles of their ligands in pregnancy. This study examined the spatio-temporal localization of estrogen receptor alpha (ERalpha) and progesterone receptor (PR) in the uterus of sika deer (Cervus nippon) to determine the estrogen and progesterone action ...
Franczak Anita A Department of Animal Physiology, University of Warmia and Mazury in Olsztyn, Oczapowski 1A, 10-718 Olsztyn, Poland. - - 2008
Previously, we found that in addition to embryos, the uterine tissues may be a source of estradiol-17beta (E(2)) during early pregnancy in the pig. The aim of the present study was to determine whether porcine endometrium and myometrium secrete androgens - androstenedione (A(4)), testosterone (T) and estrone (E(1)) during early ...
Amstislavsky S - - 2009
Despite efforts undertaken to conserve the endangered European mink, its reproduction is still poorly studied. The aim was to study its reproductive cyclicity, faecal progesterone concentration and ovarian changes during early pregnancy, with the emphasis on the pre-implantation period and implantation. During the 2004 breeding season, oestrous cycle was monitored ...
Ahn, Hyo Won, 1982-
During early pregnancy in ruminants, progesterone (P4) from the corpus luteum (CL) and interferon tau (IFNT) from the conceptus act on the endometrium to regulate genes including interferon stimulated genes (ISGs) that are hypothesized to be important for uterine receptivity and conceptus growth. Previous custom ovine cDNA array analyses identified ...
Woclawek-Potocka Izabela - - 2009
Lysophosphatidic acid (LPA) modulates prostaglandin (PG) synthesis via LPA receptor 3 (LPAR3) in the murine endometrium. The lack of functional LPAR3 in mice may lead to embryo mortality. In the present study, we examined the role of LPA in the bovine uterus. We confirmed that LPA is locally produced and ...
Ma Hai-Lan - - 2008
T-lymphoma invasion and metastasis inducing protein 1 (Tiam1) is involved in tumorigenesis processes, including cell migration, adhesion and invasion, proteolysis, cytoskeleton reorganization, cell morphological transformation and intracellular signaling. These processes are also critical for embryo implantation, although the role of Tiam1 during embryo implantation remains poorly understood. The aim of ...
Bauman Joan E - - 2008
Accurate detection of pregnancy is a useful tool in zoo management and husbandry, conservation breeding programs and research settings. Our study evaluated the ability of a commercial relaxin hormone assay used in domestic dogs (ReproCHEK(TM)) to accurately detect pregnancy through plasma analysis in two wolf and two fox species. The ...
Karaca F - - 2009
This trial was conducted to evaluate the effectiveness of multiple eCG injections in the induction of estrus and pregnancy in Colored Mohair goats during the anestrus season. It was also aimed to determine total dose of eCG required for induction of estrus. Ten multiparous and lactating goats were used. The ...
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