Search Results
Results 551 - 600 of 1198
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Min G - - 1997
Recently, it was demonstrated that endogenous relaxin promotes growth of the vagina during the second half of pregnancy in rats and that administration of porcine relaxin promotes growth of the uterus in nonpregnant or early pregnant gilts. This study examined the effects of circulating relaxin on growth of both the ...
Lammers W J - - 1997
The propagation of individual action potentials during spontaneous bursts of activity in isolated pregnant rat myometrium in the final stage of pregnancy was analyzed. Simultaneous recordings from 240 extracellular recording sites (inter-electrode distance 1 mm) made it possible to reconstruct, in spatial and temporal details, the conduction of the electrical ...
Parry L J - - 1997
Mesotocin (MT), the oxytocin-like peptide of the tammar wallaby (Macropus eugenii) is important for delivery of live young. The tammar mesotocin receptor (MTR) was first characterized using the iodinated oxytocin receptor antagonist [125I]d(CH2)5 [Tyr(Me)2, Tyr4, Orn8, Tyr-NH(2)9]-vasotocin. MTR concentrations were then measured in matched samples of gravid and nongravid myometrium ...
Geisert R D - - 1997
Cathepsin L has been proposed to be involved with the endothelial-chorial type of placentation in the cat. Little information concerning the presence and secretion of cathepsin L is available for a species with noninvasive epitheliochorial placentation such as the pig. Cathepsin L activity in uterine flushings and endometrium from gilts ...
Günzel-Apel A R - - 1997
The blood coagulation status was studied in 31 bitches of different breeds during 33 oestrous cycles and during nine pregnancies. Two other bitches were ovariohysterectomized and received subcutaneous injections of oestradiol benzoate for 7 consecutive days. Blood samples were taken in early and late follicular phases, at ovulation, at day ...
Nakano R - - 1997
Although luteinizing hormone (LH) of the anterior pituitary is considered primarily responsible for the initiation of luteinization in most species, the mechanisms governing the subsequent life and death of the corpus luteum vary among species. In women and in nonhuman primate, the corpus luteum derives its support from LH that ...
Kida H - - 1997
Our aim was to examine the changes in spatiotemporal tenascin (TN) expression in mouse uterus during early pregnancy, when the uterine tissue undergoes a tremendous restructuring. Using immunohistochemistry and in situ hybridization, the changes in distribution of TN protein in mouse uterine tissues in pregnancy Day 0 through Day 5 ...
Forst J - - 1997
The etiology of inborn hip dysplasia is unknown. In general, a multifactorial genesis is assumed. The influence of hormones on the development of the fetal hip joint and its stability is discussed as well as mechanical influences. This study was carried out with the intention to examine the correlation between ...
Jablonka-Shariff A - - 1997
To determine the relationship between cellular proliferation and the presence of FGF-1 and FGF-2 in the ovine corpus luteum (CL) during early pregnancy, ewes received an intravenous injection of bromodeoxyuridine (BrdU) 1 h before slaughter (n = 3/day) on day 12 after estrus (nonpregnant) or on days 12, 18, 24 ...
Dalin A M - - 1997
Over a period of approx. 15 months, post-mortem (PM) examinations were made on genital organs (34 gilts and 81 sows) from a sow-pool with reproductive disturbances. Anamnestic data on the animals included information about parity number, date of farrowing, dates of weaning, oestrus and service, and cause of culling. At ...
Wanke M - - 1997
Dexamethasone was administered orally for 7.5 or 9.5 days to 80 pregnant bitches to terminate unwanted pregnancy at an outpatient clinic. Treatment was initiated at day 30-35 (n = 74) or day 45-50 (n = 6) of confirmed pregnancy using one of two dosages. In 62 bitches, dexamethasone was administered ...
Madej A - - 1997
Twenty Polish Landrace gilts were grouped immediately after mating as follows: Experiment I-- Group 1 (5 gilts), control animals and Group 2 (5 gilts), injected i.m. with dexamethasone (30 mg/kg) at 12-h intervals from day 13 to day 22 of pregnancy; Experiment II--Group 3 (5 gilts), injected i.m. with corn ...
Sutton D J - - 1997
A field investigation was undertaken in mated bitches to assess the efficacy and safety of a low dose of oestradiol benzoate (0.01 mg kg-1), given by subcutaneous or intramuscular injection, on days 3, 5 and sometimes day 7 after mating. Twenty-five veterinary practices in the UK collected data from 358 ...
Negishi H - - 1997
The objective of the study was to clarify the potency and action of cabergoline, a dopamine agonist, in preventing and terminating pregnancy in rats. Cabergoline administered s.c. to female rats on days 1, 2 and 3 of pregnancy prevented implantation of the fertilized ova and development of the embryos. The ...
Harazono A - - 1996
The effect of tributyltin chloride (TBTCl) administered during early pregnancy on pregnancy maintenance was evaluated in rats. Inseminated females were orally administered TBTCl at a dose of 0, 8.1, 12.2 or 16.3 mg/kg on day 0 through day 7 of pregnancy. Females were sacrificed on day 20 of pregnancy and ...
Kojima H - - 1996
Pregnancy-dependent mammary tumors (PDMT) of GR/A mice and transplantable PDMT (TPDMT-4 line) in DDD mice, are exceptionally stable in hormone dependence, continue to grow until parturition and regress soon after delivery. In order to study the regression mechanism of PDMT and TPDMT-4, morphological and biochemical changes were examined in the ...
Burton P J - - 1996
Myometrial function in pregnancy is regulated by a range of hormonal stimuli, including glucocorticoids, particularly in the period leading up to parturition. Glucocorticoid hormone action is dependent not only on expression of glucocorticoid receptor (GR) within target cells, but also on local expression of the enzyme 11beta-hydroxysteroid dehydrogenase (11betaHSD). Therefore, ...
Wagner C K - - 1996
Pregnancy and parturition are accompanied by unique behavioral changes. Only some of the neural mechanisms behind the dramatic changes in behavior are understood. Estrogen's action within the medial preoptic nucleus (MPN) is necessary for the induction of maternal behavior around the time of parturition, and estrogen acts within the ventromedial ...
Kawarabayashi T - - 1996
OBJECTIVE: Our purpose was to compare the effects of peptidyl and nonpeptidyl oxytocin antagonists on the pregnant rat uterus in relation to the progress of gestation. STUDY DESIGN: Pregnant rats with gestational ages of 17 and 21 days were used. A saturation binding of tritiated oxytocin to myometrial membrane preparation ...
Vallet J L - - 1996
It has been hypothesized that conceptus estrogens influence endometrial protein secretion during pregnancy in swine. To test this hypothesis, the effect of estrone and estradiol treatment from d 30 to 60 of pregnancy or pseudopregnancy on endometrial protein secretion was investigated. Pregnant (P; n = 16) and pseudopregnant (PP) gilts ...
Wijayagunawardane M P - - 1996
Changes and local distribution of oviductal progesterone (P(4)) concentration during the estrous cycle and early pregnancy in cows were investigated. Intact reproductive tracts were collected from 16 Holstein cows at an abattoir. Samples were classified in to 4 stages (follicular, postovulatory, luteal and early pregnant,< 20 d) based on visual ...
Gastal M O - - 1996
The temporal relationships among day of conceptus fixation (cessation of mobility), conceptus diameter, uterine tone, uterine contractility, and myometrial and endometrial thickness of the middle and caudal segments of the uterine horns were assessed in 13 pony mares with fixation in the caudal segment of a uterine horn. The mean ...
Ginther O J - - 1996
Follicles were monitored daily by ultrasound and blood samples for FSH assay were collected daily from eight heifers from day 90 of pregnancy to the emergence of the first postpartum follicular wave. Follicles > or = 6 mm in diameter emerged in groups or waves in each heifer (P < ...
Unezaki S - - 1996
To clarify the regulation of prostaglandin F2 alpha (PGF2 alpha) production in vivo in mice during pregnancy and the estrous cycle, we injected [3H]PGF2 alpha i.v. into female mice and determined the structures of three urinary metabolites by gas chromatography-mass spectrometry. The compounds were 5,7,11-trihydroxy-tetranor-prosta-9-enoic acid (FUM-I), 5,7,11-trihydroxy-tetranor-prostanoic acid (FUM-II), ...
Kristiansson P - - 1996
In order to analyse the relationship between the ovarian response to stimulation in in-vitro fertilization (IVF) treatment cycles and relaxin concentrations during subsequent pregnancies, 31 healthy women pregnant after IVF treatment were studied prospectively. The maximum number of follicles observed from day -4 to day -2 in relation to ovum ...
Edgerton L A - - 1996
Thirty-one sows were used in an experiment designed to determine whether the ability of the porcine uterus to release prostaglandin (PG) F2 alpha in response to oxytocin was suppressed in pregnancy and pseudopregnancy. Sows were assigned to one of three treatment groups: nonbred (nonpregnant) controls (n = 8), pseudopregnant (5 ...
Yeko T R - - 1996
Investigators have shed new light on the precise manner by which human chorionic gonadotropin rescues and regulates corpus luteum function in normal and abnormal pregnancy states. It has also been shown using ultrasound that both an undetectable or shrinking corpus luteum volume are predictive of poor pregnancy outcomes. Ultrasound and ...
Novaro V - - 1996
Embryonic implantation is a complex process in which both maternal and embryonic signals are involved. In the present study, we evaluated changes in uterine prostaglandins production and nitric oxide synthase (NOS) activity during the course of early pregnancy and their interaction during implantation in rats. Uterine phospholipase A2 (PLA2) activity ...
Caba M - - 1996
Mother rabbits construct an elaborate maternal nest before parturition and display a single, brief, daily nursing bout throughout lactation. These features present a unique model for investigating the relevance of changes in neuroendocrine secretion associated with pregnancy and parturition for the regulation of maternal behavior. In the present study we ...
Skidmore J A - - 1996
The ovaries and uteri were removed from four pregnant camels on days 14, 25, 35 and 56 after ovulation. The day 14 and 25 uteri were perfuse-fixed with 3 per cent glutaraldehyde: 3 per cent paraformaldehyde whereas the day 35 and 56 specimens were opened dorsally for photography before biopsies ...
Milvae R A - - 1996
The function of the corpus luteum (CL) is a key element in many reproductive processes including ovulation, length of the estrous cycle, recognition of pregnancy and embryo survival in all mammalian species. The main function of the CL is to produce progesterone which acts on its tissues to prepare them ...
Cooper J R - - 1996
The Army has proposed using a liquid propellant (XM46) composed of hydroxylammonium nitrate (HAN) and triethanolammonium nitrate (TEAN) in its Advanced Field Artillery System. This study was undertaken to determine the potential threat to the unborn fetus should female Army personnel become exposed to this compound during pregnancy. Timed pregnant ...
Illingworth P J - - 1996
This study investigated the forms of inhibin released into the circulation 1) in very early pregnancy, 2) after stimulation of the corpus luteum by exogenous hCG, and 3) in abnormal and failing human pregnancy. Samples were assayed by enzyme-linked immunosorbent assays for inhibin A, inhibin B, and inhibin pro-alphaC-related immunoreactivity ...
Petersen L K - - 1996
Unmeasurable serum relaxin concentrations were found in repeated serum samples taken during two subsequent pregnancies in a woman pregnant after in vitro fertilization in artificial cycles. Despite the absence of relaxin both pregnancies were carried out normally until term except for symptoms of pelvic girdle relaxation. Labour induction was attempted ...
Strömstedt M - - 1996
Implantation is initiated on day 4 in the mouse and on day 13 in the pig. The preimplantation pig blastocyst synthesizes steroid hormones, but whether preimplantation rodent embryos also have this ability has remained unresolved for the last two decades. In this study, the mRNAs encoding NADPH-cytochrome P450 reductase (P450-reductase), ...
Bazer F W - - 1996
Trophectoderm of ruminant conceptuses (embryo and associated membranes) secrete tau interferons (IFN tau) as the pregnancy recognition signal. Secretion of IFN tau on gestational days 12-13 for sheep and gestation days 14-17 for cows and goats is critical for pregnancy recognition. IFN tau acts on uterine epithelium to suppress estrogen ...
Roberts R M - - 1996
A type I interferon known as IFN-tau is expressed massively by the outer epithelium (trophectoderm) of the preimplantation trophoblast of ruminant ungulate species, such as cattle and sheep, for a few days during early pregnancy. They signal to the mother that she is pregnant and indirectly prevent regression of the ...
Hansen A - - 1996
BACKGROUND: The pregnancy associated hormone relaxin induces loosening of the pelvic ligaments in several species. This study was undertaken to evaluate whether pregnant women with symptom-giving girdle relaxation had increased serum relaxin concentrations during pregnancy. METHOD: Serum relaxin concentrations were measured in 38 pregnant women with symptom-giving pelvic girdle relaxation ...
Townson D H - - 1996
The known accumulation of macrophages in corpora lutea (CL) at the time of luteal regression prompted us to investigate whether the chemoattractant protein monocyte chemoattractant protein-1 (MCP-1) is expressed in the rat CL. On the day of confirmed mating (Day 0 of pregnancy), regressing CL from the previous (nonfertile) estrous ...
Johnson J A - - 1996
To gain insights into 1,25-dihydroxyvitamin D3 receptor (VDR) function during fetal bone development, we examined fetal rat tissues from gestational days 13-21 for the presence and distribution of VDR using immunohistochemistry. Prior to ossification, VDR epitopes were observed in the mesenchyme condensing to form skeletal tissues, on day 13 in ...
Tsuma V T - - 1996
The effect of group housing sows during early pregnancy on maternal endocrine changes and on embryonic survival was studied. Twenty crossbred (Swedish Yorkshire x Swedish Landrace) primiparous sows were used. On day 11 +/- 1 of pregnancy 3 unacquainted sows were randomly assigned to a single pen measuring 3 m ...
Kita I - - 1995
Corpora lutea of the sika deer (Cervus nippon, Cervidae) were histologically examined in order to elucidate their retrograding processes after parturition. They showed a remarkable regression within one month as luteal cells decreased in number and, by nine months after parturition, turned into masses of blood vessels containing many arterioles ...
Liu H C - - 1995
Luteal-phase estrogen and progesterone concentrations were measured every other day and used to monitor the corpus luteum activity. The patterns of estrogen and progesterone concentrations were compared relative to the day of endogenous human chorionic gonadotropin (hCG) detection (defined as the day of implantation). The relationship between estrogen and progesterone ...
Kim S G - - 1995
Microsomal epoxide hydrolase (mEH) protein and messenger ribonucleic acid (mRNA) levels were assessed in maternal rats during pregnancy and mEH gene expression was compared with cytochrome P450 expression. Immunoblot analysis using goat anti-rat mEH antibody showed that hepatic mEH levels in adult rats at day 12 of gestation were comparable ...
Silversides D W - - 1995
To determine if and when short-term ablation of androgen action compromises the development of the male reproductive tract in mice, the androgen receptor antagonist hydroxyflutamide was administered orally to pregnant FVB/N mice and the reproductive tracts of the male offspring were examined when adult. Hydroxyflutamide (30 mg per day) for ...
Roth T L - - 1995
Pregnancy rates are low and litter sizes generally small when assisted reproduction techniques are used in gonadotropin-treated felid (cat) species. A prerequisite to determining whether or not abnormal morphological changes in the uterine lumen or corpus luteum (CL) are related to this reproductive failure is the documentation of normal histological ...
Glock J L - - 1995
Our purpose was to characterize the growth pattern of the corpus luteum of early normal human pregnancy and correlate this growth with the corpus luteum hormone products: relaxin, progesterone, estradiol and 17-hydroxyprogesterone. A prospective study of seven patients was initiated at a mean gestational age of 4 weeks and 2 ...
Christensen S - - 1995
The objective of this study was to investigate the localization and hormonal regulation of smooth muscle myosin II (SMM II) and alpha smooth muscle actin (alpha SMA) in the baboon uterus, since cytoskeletal proteins are involved in secretory function and morphological transformation. Uterine tissue was obtained from baboons 1) during ...
Goto Y - - 1995
The weights of pregnancy-dependent mammary tumors (PDMT) of GR/A mice continued to increase until parturition and decreased soon after delivery; however, mitotic indices in epithelial cells and stromal cells of PDMT reached a maximum plateau on Day 18-19 of pregnancy and decreased thereafter. Growth of PDMT in progesterone-treated mice on ...
Ozbilgin A - - 1995
Bone-marrow aspiration and biopsy material samples obtained from two patients, one diagnosed as visceral and other as cutaneous leishmaniasis, were inoculated in Novy, McNeal, Nicolle (NNN) medium and nutrient broth (NB), containing fetal calf serum (FCS), penicillin and streptomycine. Both media were incubated at 27 degrees C for 10 days ...
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