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Results 401 - 450 of 470
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Israel E J - - 1986
Prematurity and fetal death are common complications in patients with cholestasis of pregnancy. Both conditions appear to be associated with abnormal patterns of uterine activity. We studied the oxytocin-induced contractile activity in uterine strips taken from patients with cholestasis of pregnancy (n = 6) and from women with normal pregnancy ...
Weitman S D - - 1986
The mechanism of enhanced parathion/paraoxon toxicity during pregnancy was examined. Enhanced toxicity following exposure to paraoxon in the pregnant mouse as determined by cholinesterase suppression was observed at 0.10 and 0.58 mg/kg after ip administration on Day 19 of gestation. However, there were no significant differences in cholinesterase activity between ...
Durham S - - 1985
A crossover experimental design was used to examine the effects of saline (SAL) vs. taurocholate (TC) infusion on hepatic excretory function in isolated perfused livers from pregnant (19-21 days gestation) and nonpregnant female rats. Bile flow, bile acid concentration, bile acid secretory rate, dibromosulfophthalein (DBSP) concentration in bile, and DBSP ...
Noronha A - - 1985
This article focuses on epilepsies, autoimmune diseases such as multiple sclerosis and myasthenia, serious problems associated with stroke and pseudotumor cerebri, and some common problems such as headaches and the carpal tunnel syndrome, examining the effects of pregnancy and the puerperium on these disorders and the influence of these disorders ...
Yip D M - - 1985
Mild abnormalities of liver function tests are frequently seen in pregnancy but return to normal after delivery. A raised serum alkaline phosphatase is common, along with a decline in the serum albumin, but the aminotransferases remain within normal limits. The physician must interpret abnormal liver function tests in pregnancy with ...
Sasser L B - - 1985
The ability of Cd to induce the synthesis of fetal hepatic metallothionein (MT) was investigated in rat fetuses exposed to Cd throughout gestation via the mother's drinking water or injected directly with Cd through the uterine wall on Day 18 of gestation. On Day 21 all dams were killed and ...
Shukla V K - - 1985
A case of a 28 weeks primary hepatic pregnancy in a 25 year old female is reported. A live male fetus weighing 1300 g was delivered after laparotomy and the placenta was left intact. The uterus was of 8 weeks size with patent tubes. The patient made an uneventful recovery.
Mintz M C - - 1985
Real-time sonography was used to examine the biliary tracts of 103 pregnant women. Common hepatic duct size, degree of right hydronephrosis, and presence of gallstones were noted. There were three important observations: (1) The top normal size of the common hepatic duct was 5 mm; (2) no correlation was found ...
Loevinger E H - - 1985
Spontaneous rupture of the liver associated with pregnancy is a rare and very serious complication, usually occurring in association with eclampsia or preeclampsia. Survival has generally been dependent on early recognition of characteristic signs and symptoms and prompt surgical intervention. Even with surgery, maternal mortality approaches 40% and fetal mortality ...
Whitehouse L W - - 1985
Rifampin pretreatment in the rabbit caused a selective induction of hepatic parameters resembling in some respects phenobarbital induction. Concomitant with induction, a transient selective inhibition of hepatic parameters was also observed. This two-fold effect of rifampin offers an explanation for the discrepancy surrounding the dosage and species differences in hepatic ...
Kaufman S - - 1985
The hepatic phenylalanine hydroxylating system consists of three essential components, phenylalanine hydroxylase, dihydropteridine reductase and the non-protein coenzyme, tetrahydrobiopterin. The reductase and the pterin coenzyme are also essential components of the tyrosine and tryptophan hydroxylating systems. Recent studies have shown that there are three distinct forms of phenylketonuria or hyperphenylalaninaemia, ...
Nakamura T - - 1985
Skeletal surveys were performed on a 38-year-old Japanese mother, her son and daughter. The radiographs of both children showed characteristic features of osteopathia striata. However, in the mother, the skull, mandible, and lower extremities were homogeneously sclerotic with no evidence of a striated pattern of sclerosis in her skeleton. Additional ...
Kirkinen P - - 1984
Ultrasonic measurement of the gallbladder volume was taken in 8 nonpregnant, healthy women, in 7 women with normal pregnancies and in 7 women whose pregnancies were complicated by intrahepatic cholestasis of pregnancy, in the fasting state and 30, 60, 120 and 180 min after a test meal. At the same ...
Korn-Lubetzki I - - 1984
The influence of pregnancy on multiple sclerosis was studied in 338 women by determining in each trimester of pregnancy and post partum the number of relapses and the corresponding relapse rate. Eighty-five relapses occurred in association with 199 pregnancies, most (65) in the postpartum period, and a low number of ...
Callen J P - - 1984
The skin almost always shows changes during pregnancy. Some of these alterations are so predictable as to be considered normal. Not nearly so common are a host of pruritic dermatoses, including pruritus gravidarum, herpes gestationis, pruritic urticarial papules and plaques of pregnancy, Spangler 's papular dermatitis of pregnancy, and impetigo ...
Niemi M L - - 1984
The clinical trial was primarily designed to determine to what extent the stiffness of toothbrush bristles and the abrasiveness of dentifrices influence the degree of gingival erosion. Further, the plaque removing effectiveness of the toothbrushes and dentifrices tested was evaluated. 24 dental hygienist students with clinically healthy gingivae volunteered for ...
Laatikainen T - - 1984
Cardiotocography (CTG) and serum total bile acid level were used in the perinatal surveillance of 117 pregnancies with intrahepatic cholestasis. Signs of fetal distress occurred more commonly in cholestasis pregnancies with high maternal bile acid levels. Despite careful monitoring one intrauterine fetal loss occurred without any warning signs in CTG. ...
Mitchell R W - - 1984
A case of primary hepatic pregnancy in which the presenting features were suggestive of ruptured ectopic pregnancy is described. The bleeding area on the liver was oversewn and the patient recovered uneventfully. Primary hepatic pregnancy is briefly discussed.
Gonzalez G D - - 1984
We have described a pregnant patient who had spontaneous hepatic rupture, an uncommon but devasting complication of pregnancy, with both maternal and fetal mortality of 60% reported. Prompt uterine evacuation and abdominal exploration with surgical control of the hepatic hemorrhage best assures maternal and fetal survival. Hepatic artery ligation may ...
Ekberg H - - 1984
Hepatic rupture during pregnancy is related to toxaemia and is most often fatal. Epigastric pain and signs of intra-abdominal bleeding are the most common presenting symptoms. In previous reports liver surgery has been considered the method of choice in all patients. However, we have successfully treated a patient with bilateral ...
Rajka G - - 1984
A 31-year-old woman developed typical clinical and laboratory signs of PCT at the end of her second pregnancy coincident with the summer season. She had elevated liver function values without history of alcoholism, hepatitis or chemical liver damage. She had taken oral contraceptive only before her first pregnancy which was ...
Feurle G E - - 1984
In order to study some of the molecular events during the hepatic passage of gastrin, we perfused sulfated natural porcine gastrin (G17 II) through isolated pig livers. The disappearance half time of G17 II was about 20-30 min when the starting gastrin concentrations were greater than 100 pM; lower concentrations ...
Stock B H - - 1984
The results of both isolated tissue and whole animal experimentation, whilst showing some unexplored inconsistencies, suggest that late pregnancy is associated with a reduced ability of the liver to metabolise foreign compounds. The mechanism of this reduced capacity and the physiological reason for it are unclear but such change does ...
Aziz S - - 1983
Spontaneous rupture of the liver during pregnancy seems to represent an extreme vascular complication of toxemia. The very high mortality rate has generally been attributable to uncontrolled hemorrhage. However, control of the hemorrhage may not be sufficient to achieve recovery. Hepatic dysfunction may proceed to necrosis associated with multiple organ ...
Caswell A M - - 1983
Prolongation of pregnancy for 1.5 days by the injection of progesterone leads to a decrease in maternal liver glycogen content and an increase in blood ketones without alteration in the activity of hepatic hydroxymethylglutaryl-CoA synthase, an enzyme of ketogenesis. Fetal hepatic mitochondrial hydroxymethylglutaryl-CoA synthase activity increases with increasing postmaturity in ...
Romero R - - 1983
A 30-year-old woman developed pruritic urticarial papules and plaques of pregnancy (PUPPP). The eruption, characterized by generalized edematous, erythematous plaques and nonexcoriated papules, began in the third trimester of pregnancy and was responsive to oral corticosteroids. While the etiology of PUPPP is unknown and the clinical features (urticarial plaques) sometimes ...
Innis S M - - 1983
The effect of administration of cholestyramine on plasma cholesterol level and hepatic cholesterol and bile acid synthesis was investigated in pregnant and nonpregnant rats. Rates of cholesterol and bile acid synthesis were reduced by pregnancy in both control and cholestyramine-treated rats. Administration of cholestyramine throughout gestation and pregnancy failed either ...
Holmes R C - - 1983
The terminology of the specific dermatoses of pregnancy has become increasingly confusing, with several names in use for identical clinical disorders. On the basis of our own study of sixty-four patients and a review of the literature, we propose a simplified classification: (1) herpes gestationis (pemphigoid gestationis); (2) polymorphic eruption ...
Feingold K R - - 1983
Hypercholesterolemia occurs during pregnancy in rats and human beings, beginning in the second trimester and increasing progressively throughout the remainder of pregnancy. The present study quantified de novo cholesterol synthesis in vivo and in vitro in pregnant animals using 3H2O as the substrate for measuring cholesterogenesis. In the third trimester, ...
Nuzzo G - - 1983
A new case of Budd-Chiari syndrome following pregnancy is reported. The patient, shortly after her second normal delivery, showed clinical evidence of hepatic venous outflow impairment. The diagnosis of Budd-Chiari syndrome was supported by angiographic studies, computed tomography, liver scanning and histology. Because of the poor results reported in the ...
Michaud R M - - 1982
Papular dermatitis of pregnancy is a rare pruritic eruption of widespread urticarialike papules. The eruption developed in a 31-year-old woman during the third trimester of her second pregnancy. Urine chorionic gonadotropin (UCG) levels were elevated. A biopsy specimen of an involved papule showed spongiosis and a perivascular lymphocytic infiltrate in ...
Dubois R S - - 1982
The course and outcome of pregnancy in two adolescents with chronic active hepatitis is described. Pregnancy was uneventful in both patients apart from mild biochemical deterioration in one patient. Both infants are entirely normal. One mother died 4 1/2 months after delivery from primary pulmonary hypertension, an extrahepatic manifestation of ...
Sowa B - - 1982
Female Wistar rats received cadmium (Cd) in drinking water at a concentration of 100 ppm before and during pregnancy, prior to gestation only, and during gestation only. For the quantitative determination of metallothionein, the 203Hg-saturation method was used. Each of the 3 exposure treatments led to a decrease of the ...
Britton R C - - 1982
A review of the case histories of 53 patients with established cirrhosis who had 83 pregnancies and 38 noncirrhotic patients with varices who had 77 pregnancies suggests that conception may occur in patients with varying degrees of hepatic decompensation, that sustaining gestation to term and delivery is unlikely to overtax ...
Shalev E - - 1982
Epidemiological, clinical and laboratory data were obtained relating to 89 pregnant women who suffered from viral hepatitis during the period 1967-1977 in Israel. The obstetrical data, course of labor and details about the newborn, were all compared with the accepted obstetrical standards in Israel and abroad. A follow-up study was ...
Charles-Shannon V L - - 1981
The ontogeny of hepatic metallothioneins (Mt) in fetal tissue as related to dietary and hepatic Zn was investigated. Sixty 6-month-old female rats were divided into two groups and given either double-distilled water or water containing 700 mug of Zn per milliliter. Dams from each group were killed on 16, 19, ...
Reyes H - - 1981
To test the hypothesis that intrahepatic cholestasis of pregnancy represent an abnormal reaction to estrogens in genetically predisposed individuals, the sulfobromophthalein disappearance curve from blood was compared before and after ethinyl estradiol administration (0.1 mg/day, during 6 days) in multiparous women with or without a past history of intrahepatic cholestasis ...
Ahmed A R - - 1981
Pruritic urticarial papules and plaques of pregnancy is a self-limiting disease generally seen in the first pregnancy during the third trimester. Lesions are frequently present centrally and are intensely pruritic. Mucous membranes are usually not involved. Histology shows a normal epidermis with mild perivascular lymphohistiocytic infiltrate. Blood vessels, cutaneous appendages, ...
Uhlin S R - - 1981
A 19-year-old mother had pruritic urticarial papules and plaques of pregnancy. Similar eruptions were found on her newborn son. This recently recognized eruption of pregnancy, characterized by pruritic papules, papulovesicles, and urticarial plaques, has been seen previously only in mothers. The histologic findings are nonspecific and may include spongiosis, a ...
Khuroo M S - - 1981
A prospective field study was carried out during an epidemic of non-A non-B hepatitis for determining the incidence and severity of hepatitis in pregnant women, nonpregnant women of child bearing age and men (15 to 45 years old). In 36 (17.3 percent) of 208 pregnant women viral hepatitis developed, as ...
Cardozo L D - - 1980
Thirty women with detrusor instability (27 cases idiopathic, and three secondary to multiple sclerosis) completed a double-blind, cross-over trial of the prostaglandin synthetase inhibitor flurbiprofen and a placebo, results being evaluated by questionnaire and cystometry. Frequency, urgency, and urge incontinence were all significantly reduced with flurbiprofen (P less than 0.001, ...
Ylöstalo P - - 1980
The aim of the present study was to determine whether pregnancy complications themselves influence the conversion rate of dehydroepiandrosterone sulphate (DHAS) to oestrogens during pregnancy. 100 mg DHAS was given intravenously to seven women with intrahepatic cholestasis of pregnancy, nine women with preeclampsia, nine diabetics, ten with twins and eight ...
Samuelson K - - 1980
Radioimmunoassay has been used to quantitate the conjugates of cholic and chenodeoxycholic acid in venous blood from women in different stages of normal pregnancy and in patients with recurrent intrahepatic cholestasis of pregnancy (RCP). The levels of cholic and chenodeoxycholic acid were shown to be within normal limits throughout uncomplicated ...
Steven M M - - 1979
The outcome of pregnancy in chronic active hepatitis (CAH) was studied retrospectively, together with a survival analysis of patients and a comparison of fertility with that expected from controls drawn from the normal Australian population. Clinical records of 73 cases of CAH included 37 women who were potentially fertile (aged ...
Infeld D S - - 1979
The course and possible risks of pregnancy in 7 women between the ages of 20 and 30 yr with chronic-persistent hepatitis (CPH) were evaluated. Ten pregnancies occurred in these women during the follow-up period which ranged from 3 to 8 yr. Four of the fetuses were aborted electively for nonmedical ...
Giusti G - - 1979
Concentrations of numerous sulfate steroids were checked in the plasma of 10 women in normal pregnancy (NP), 21 women with intrahepatic cholestasis of pregnancy (ICP) and 10 pregnant women suffering from viral hepatitis with jaundice (VHP). A considerable increase in 5 alpha pregnane and 5 beta pregnane 3 alpha, 20 ...
Lawley T J - - 1979
We report an intensely pruritic cutaneous eruption that occurs in the third trimester of pregnancy. The clinical manifestations include erythematous urticarial papules and plaques that begin on the abdomen and spread to involve the thighs and occasionally the buttocks and arms. This dermatosis appears to be clinically distinct from previously ...
Johns A - - 1979
A case is presented in which pregnancy occurred after jejunoileal bypass for treatment of obesity. The pregnancy was complicated by coagulation defects apparently on the basis of liver damage secondary to the bypass. Pertinent literature is reviewed, and the conclusion is reached that although the majority of patients becoming pregnant ...
Shwer M - - 1978
A woman who developed hepatitis B during the 3rd trimester of pregnancy gave birth to a preterm, small-for-gestational-age infant whose blood also contained hepatitis B antigen. The effects of viral hepatitis on the fetus are reviewed and an approach to the management of such pregnancies is formulated.
Rahbari H - - 1978
Sixteen cases of pruritic papules of pregnancy were collected during a 32-month period. This dermatosis was introduced to the literature in 1962 but no histopathologic study of it has been published. Histopathologic presentation of pruritic papules of pregnancy is that of toxic dermatitis. This finding is not characteristic of this ...
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