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Watson Kendra D - - 2012
: Systemic mastocytosis is a rare medical disorder in which an increased number of mast cells can precipitate immediate hypersensitivity reactions, leading to hypotension, shock, and death. It is characterized by persistent elevated serum tryptase levels. The few published reports on pregnancy complicated by systemic mastocytosis indicate favorable maternal and ...
Ko Jennifer K Y - - 2012
: Molar pregnancy found in a cesarean scar is exceedingly rare. It can be challenging to manage and can have potentially catastrophic consequences. : A 34-year-old multigravid woman presented with persistent symptoms of pregnancy after a surgical termination of pregnancy. Cesarean scar molar pregnancy was suspected on ultrasonography, and suction ...
Raymond Elizabeth G - - 2012
To assess the safety of abortion compared with childbirth. We estimated mortality rates associated with live births and legal induced abortions in the United States in 1998-2005. We used data from the Centers for Disease Control and Prevention's Pregnancy Mortality Surveillance System, birth certificates, and Guttmacher Institute surveys. In addition, ...
Hess Camber M - - 2012
Maternal nutrition is an important determinant of birth outcome and infant health. In this study, we sought to identify the current knowledge of prenatal nutrition among women in Tucumán, Argentina, to examine the extent to which knowledge was implemented and to identify opportunities for improvement in prenatal care and education. ...
Rosenberger Laura H - - 2012
Fifty percent of aortic dissections in women younger than 40 years occur in association with pregnancy. Of these, half of type B dissections occur in the postpartum period. A 30-year-old woman was status post spontaneous vaginal delivery at 30 weeks of gestation for fetal death, complicated by an eclamptic seizure. ...
Rosa Renata Giardini - - 2012
During pregnancy, the mouse pubic symphysis undergoes expansion and remodeling resulting in formation of a flexible and elastic interpubic ligament allowing passage of a term fetus. In the current study, we sought to identify and characterize components of the extracellular matrix that likely play an important role in elongation and ...
Khankin Eliyahu V - - 2012
To investigate the role of FMS-like tyrosine kinase 1 (FLT1, also known as VEGFR1) signaling during pregnancy, mice were injected with anti-FLT1 neutralizing antibody (Ab) beginning on Gestational Day 8 or 12 and every other day thereafter until Day 18; vehicle-only injected mice served as controls. Uterine artery blood flow ...
Gao Haijun - - 2012
Both the systemic and the uteroplacental renin-angiotensin system (RAS) display dramatic changes during pregnancy. However, whether gestational protein insufficiency affects the expressions of RAS in the placenta remains unknown. In this study, we hypothesized that the expression of Ace2 in the placental labyrinth was reduced by maternal protein restriction. Pregnant ...
Zanotti-Fregonara Paolo - - 2012
The authors estimated the fetal radiation dose from [(18)F]-FDG in a rare case of a woman who underwent a PET/CT scan during the second trimester of pregnancy. The patient, a 27-y-old female with a paraganglioma, received 181.3 MBq [(18)F]-FDG. From the concentrations of radioactivity measured on the images, the time-integrated ...
Huang Hao - - 2012
To identify risk factors for pregnancy outcomes in couples treated with intracervical or intrauterine insemination, with or without superovulation for unexplained or male-factor infertility. Secondary analysis of data from a randomized superovulation and intrauterine insemination trial. Academic medical centers. Treatment continued for four cycles unless pregnancy was achieved. Out of ...
Calza Leonardo - - 2012
Objectives: An observational, open-label study was performed to assess changes of lopinavir/ritonavir plasma concentrations during pregnancy. Methods: Adult HIV-1-infected women during the third trimester of pregnancy and on stable antiretroviral treatment including zidovudine/lamivudine plus lopinavir/ritonavir tablets (400/100 mg twice daily) were asked to participate. This group was compared with a ...
Ocal Pelin - - 2012
To investigate the association between follicular fluid homocysteine levels and embryo quality and pregnancy rates in patients undergoing assisted reproduction. Fifty infertile women who were admitted to our clinic were enrolled in the study. Ovulation induction was performed by using GnRH agonist and gonadotropins. For each patient, homocysteine level in ...
Bozdag Kubra - - 2012
Impetigo herpetiformis is a rare pustular eruption with usual onset during the third trimester of pregnancy. The disease tends to remit after delivery, but may recur in subsequent pregnancies. Here we present a recurrent case of impetigo herpetiformis with earlier onset and poor response to corticosteroids in the subsequent pregnancy. ...
Miettinen M E - - 2012
AIMS/HYPOTHESIS: Vitamin D deficiency during the fetal period or infancy is one of the suggested environmental factors for type 1 diabetes and for its increasing incidence. To test this hypothesis we compared serum 25-hydroxyvitamin D (25(OH)D) levels during early pregnancy in mothers of children who subsequently developed type 1 diabetes ...
Zavier A J Francis - - 2012
Abstract Many married women in India experience abortion in their second trimester of pregnancy. While there is an impression that second trimester abortions are now overwhelmingly used for sex selection, little is known about the extent to which second trimester abortions are indeed associated with son preference and sex selection ...
- - 2012
Approximately 400,000 teens aged 15-19 years give birth every year in the United States (1), and the teen birth rate remains the highest in the developed world. Teen childbearing is a public health concern because teen mothers are more likely to experience negative social outcomes, including school dropout. In addition, ...
Wong-Taylor Li-An - - 2012
PURPOSE: There is little published data on pregnancy outcomes in women who had conceived spontaneously after age 45 years. The aim of this review is to provide accurate information on the risks and probable outcomes of spontaneously conceived pregnancies in women over the age of 45 years, which will enable clinicians to ...
Azria E - - 2012
Please cite this paper as: Azria E, Anselem O, Schmitz T, Tsatsaris V, Senat M, Goffinet F. Comparison of perinatal outcome after pre-viable preterm prelabour rupture of membranes in two centres with different rates of termination of pregnancy. BJOG 2012; DOI: 10.1111/j.1471-0528.2011.03265.x. Objective  To assess perinatal outcomes after expectant management ...
Davis Elysia Poggi - - 2012
Experimental animal models have demonstrated that one of the primary consequences of prenatal stress is increased fear and anxiety in the offspring. Few prospective human studies have evaluated the consequences of prenatal stress on anxiety during preadolescence. The purpose of this investigation is to determine the consequences of prenatal exposure ...
Fang Hua H Department of Quantitative Health Sciences, University of Massachusetts Medical School, ACCES Bldg., 7th Floor, Office: AC7-043, 55 Lake Avenue North, Worcester, MA 01655, USA. - - 2012
The effects of tobacco exposure are typically examined by comparing groups based on a cut-score of self-reported number of cigarettes or bioassays collected in cross-sectional studies. This study introduces a new fuzzy clustering method that facilitates detection of subtle exposure effects by objectively deriving subgroups from modeling multidimensional exposure measures. ...
Xiang D J - - 2012
This was a retrospective study of the effectiveness of trichosanthin (TCS), an active component isolated from the Chinese herb root tuber of Trichosanthes kirilowii on 140 cases of ectopic pregnancy with higher levels of β-human chorionic gonadotropin (β-hCG) managed with a single dose of TCS treatment. Trichosanthin has been used ...
Ognibene Dayane T - - 2012
BackgroundThe purpose of this study was to investigate the contribution of renin-angiotensin system (RAS) and oxidative status on the maternal cardiovascular regulation at the end of pregnancy in normotensive and spontaneously hypertensive rats (SHR).MethodsBlood pressure (BP), mesenteric arterial bed (MAB) reactivity, mesenteric oxidative damage, protein expression, and antioxidant activities were ...
Alhusen Jeanne L - - 2012
Maternal-fetal attachment (MFA) has been associated with health practices during pregnancy, but less is known about this relationship in low-income women, and no identified studies have examined this relationship to neonatal outcomes. This longitudinal descriptive study was conducted to examine the relationships among MFA, health practices during pregnancy, and neonatal ...
Braun Joe M - - 2012
Gestational phthalate and bisphenol A (BPA) exposure may increase the risk of adverse maternal/child health outcomes, but there are few data on the variability of urinary biomarkers before and during pregnancy. We characterized the variability of urinary phthalate metabolite and BPA concentrations before and during pregnancy and the ability of ...
Hata Toshiyuki - - 2012
The objective of this study was to measure the fetal brain volume (FBV) and vascularization and blood flow using transvaginal 3-D power Doppler (3DPD) ultrasound late in the first trimester of pregnancy. 3DPD ultrasound examinations with the VOCAL imaging analysis program were performed on 36 normal fetuses from 10-13 weeks' gestation. ...
Egan N - - 2012
Please cite this paper as: Egan N, Bartels Ä, Khashan A, Broadhurst D, Joyce C, O'Mullane J, O'Donoghue K. Reference standard for serum bile acids in pregnancy. BJOG 2012;00:000-000. DOI: 10.1111/j.1471-0528.2011.03245.x. Objective  Obstetric cholestasis (OC) is a liver disorder characterised by pruritus and elevated serum bile acids (SBA) that affects ...
Ertl Rebecca - - 2012
Objectives: To determine if maternal serum levels of 25(OH)D at 11-13 weeks' gestation are altered in pregnancies that subsequently deliver small for gestational age (SGA) neonates and whether the levels are related to placental function reflected in serum concentration of pregnancy-associated plasma protein-A (PAPP-A). Methods: Serum 25(OH)D and PAPP-A were ...
Hawkins Tl-A - - 2012
Please cite this paper as: Hawkins T, Roberts J, Mangos G, Davis G, Roberts L, Brown M. Plasma uric acid remains a marker of poor outcome in hypertensive pregnancy: a retrospective cohort study. BJOG 2012; DOI: 10.1111/j.1471-0528.2011.03232.x. Objective  To examine the relationship between hyperuricaemia, haemoconcentration and maternal and fetal outcomes ...
Keenan Jeffrey A - - 2012
BACKGROUNDEmbryo donation, though less often performed than other assisted reproductive technology (ART), can represent an attractive option for couples who do not wish to discard their embryos remaining after IVF, and for those who cannot or should not conceive naturally. Clinicians and potential participants could benefit from information comparing outcomes ...
Petrikke Olsen Ingrid - - 2012
Objectives Normal anatomical and physiologic development of the anal canal during and after pregnancy is scarcely documented. Here we study the anal canal, its position and volumes during and after first time pregnancy. Methods Vaginal 3D ultrasound was used in a longitudinal study measuring anatomical structures in the anal canal ...
Westbrook Rachel H - - 2012
INTRODUCTION: Optimal management during pregnancy of patients with autoimmune hepatitis (AIH) remains undefined. We therefore reviewed all patients with AIH who reported pregnancy at our centre to identify any pre-conception factors that might predict adverse outcomes. RESULTS: There were 81 pregnancies in 53 women. Median age at conception was 26 ...
Sunman Hamza - - 2012
OBJECTIVE:To describe a successful pregnancy in a patient who used fenofibrate during the first trimester.CASE SUMMARY:A 30-year-old female with a history of polycystic ovarian syndrome was referred to our department for evaluation of hypertriglyceridemia, and fenofibrate treatment was initiated. After 1 year of therapy, a gynecologic visit for menstrual cycle ...
Bieri Regina Alessandri - - 2012
OBJECTIVES: The aim of this study was to assess gingival fluid (GCF) cytokine messenger RNA (mRNA) levels, subgingival bacteria, and clinical periodontal conditions during a normal pregnancy to postpartum. MATERIALS AND METHODS: Subgingival bacterial samples were analyzed with the checkerboard DNA-DNA hybridization method. GCF samples were assessed with real-time PCR ...
Zangeneh Maryam - - 2012
OBJECTIVE: To compare 2 different methods-multiple doses of misoprostol and a combination of misoprostol and oxytocin-for termination of pregnancy in the second trimester. METHODS: Between 2006 and 2008, 120 women undergoing termination of second-trimester pregnancy in 2 hospitals in Kermanshah, Iran, were enrolled in a randomized trial comparing 2 treatments. ...
Jin Hai-Xia - - 2012
The purpose of this study was to explore the effects of cumulus cells on vitreous cryopreservation of human mature oocytes and clinical pregnancy outcomes. The study was divided into group A (cumulus cells were removed from the oocytes before freezing) containing 24 participants and 193 oocytes and group B (cumulus ...
Kolialexi Aggeliki - - 2012
OBJECTIVE: Clinical indications for fetal sex determination include risk of X-linked disorders, a family history of conditions associated with ambiguous development of the external genitalia, and some fetal ultrasound findings. It is usually performed in the first trimester from fetal material obtained through CVS and is associated with an approximately ...
Ventura Walter - - 2012
OBJECTIVE: To assess the perinatal outcomes of a subsequent pregnancy among adolescent mothers living in Peru. METHODS: A large hospital-based retrospective cohort study was conducted to evaluate singleton births during a 9-year period (2001-2009). The study population was divided into 3 groups: adolescents aged 15-19years who had 1 previous parturition ...
Yin Yongxiang - - 2012
OBJECTIVES: The purpose of this study was to examine whether adoptive transfer with in vitro expanded CD4(+)CD25(+) regulatory T cells (Tregs) could prevent immune response-mediated spontaneous abortion in mice. STUDY DESIGN: Female CBA/J mice were mated with male Balb/c as the control with normal pregnancy or with DBA/2J mice as ...
Le Ray C - - 2012
BACKGROUNDAlthough older maternal age is a risk factor for pregnancy complications, an increasing number of women delay conception until the age of 40, and some must resort to IVF with oocyte donation. Our objective was to study the association between IVF, both with and without oocyte donation, and maternal and ...
Huizink Anja C - - 2012
Background: Numerous studies have been conducted in which the most common forms of maternal substance use during pregnancy (smoking, drinking or using cannabis) and maternal stress during pregnancy and her offspring's developmental or behavioural outcome have been the focus of interest. These studies seem to suggest that any perturbation caused ...
Imbar Tal - - 2012
BACKGROUNDTriggering ovulation by GnRH agonist (GnRHa) in GnRH antagonist IVF protocols coupled with adequate luteal phase support has recently been suggested as a means to prevent ovarian hyperstimulation syndrome (OHSS). Our objective was to examine the outcome of fresh embryo transfer (f-ET) after triggering ovulation by GnRHa and providing intensive ...
Molvi Shaba N - - 2012
BACKGROUND: Pregnancy-induced hypertension (PIH) is associated with adverse fetal and maternal outcome. The role of medication to control blood pressure (BP) in mild to moderate PIH is controversial. AIMS: We conducted a prospective study to investigate whether pharmacological treatment of mild to moderate PIH is effective in improving maternal and ...
Hromadnikova Ilona - - 2012
Placental insufficiency-related complications are one of the leading causes of maternal and perinatal morbidity and mortality. This study investigated the quantification of placenta-specific microRNAs (miRNAs) in the maternal circulation during gestation in a cohort of women with normally progressing pregnancies, the differentiation between placental insufficiency-related complications and normally progressing pregnancies, ...
Devroey Paul - - 2012
To compare the efficacy and safety of highly purified menotropin (hphMG) and recombinant FSH (rFSH) for controlled ovarian stimulation in a GnRH antagonist cycle with compulsory single-blastocyst transfer. Randomized, open-label, assessor-blind, parallel groups, multicenter, noninferiority trial. Twenty-five infertility centers in seven countries. Seven hundred forty-nine women. Controlled ovarian stimulation with ...
Poon L C Y - - 2012
Objectives: To identify the best protocol for measurement of mean arterial pressure (MAP) in early pregnancy for the prediction of preeclampsia (PE). Methods: This was a prospective study in singleton pregnancies attending for a routine hospital visit at 11-13 weeks' gestation when a minimum of four recordings of MAP were ...
Sifakis Stavros - - 2012
OBJECTIVE: To investigate the possible value of maternal serum concentration of insulin-like growth factor-I (IGF-I), IGF binding protein-1 (IGFBP-1) and IGFBP-3 at 11-13 weeks' gestation in the prediction of small-for-gestational age (SGA) neonates. STUDY DESIGN: Maternal serum concentrations of IGF-I, IGFBP-1 and IGFBP-3 at 11-13 weeks were measured in 60 ...
Huang Jing - - 2012
1. To evaluate the role of placental apoptosis in mediating the reproductive and developmental toxicity of caffeine in rodents. 2. Female Kunming mice were treated with caffeine (60, 120 and 240 mg/kg per day) before and during pregnancy. The conception rate, maternal bodyweight gain, placental weight and indices of fetal developmental, including ...
Vestergaard Sonja - - 2012
BACKGROUNDPerfluorinated chemicals (PFCs) have been widely used and have emerged as important food contaminants. A recent study on pregnant women suggested that PFC exposure was associated with a longer time to pregnancy (TTP). We examined the association between serum concentrations of PFCs in females and TTP in 222 Danish first-time ...
Sekii Katsuyuki - - 2012
Few studies have investigated the relationship between myocardial tissue Doppler parameters and fetal size adjusted for gestational age and its trend has been controversial. To investigate fetal cardiac function before birth using tissue Doppler imaging (TDI: indicated by the prime symbol (')) in low-risk term pregnancies by comparing the TDI ...
Jacobs Brandiese E BE Department of Physiology, School of Medicine, University of Maryland, Baltimore, - - 2012
Endogenous cardiotonic steroids (CTS) raise blood pressure (BP) via vascular sodium calcium exchange (NCX1.3) and transient receptor-operated channels (TRPCs). Circulating CTS are superelevated in pregnancy-induced hypertension and preeclampsia. However, their significance in normal pregnancy, where BP is low, is paradoxical. Here we test the hypothesis that vascular resistance to endogenous ...
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