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Results 201 - 250 of 3020
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Nielsen Stine Yde - - 2014
A high risk for obstetric complications has been reported among women infected with Coxiella burnetii, the causative agent of Q fever, but recent studies have failed to confirm these findings. We reviewed national data collected in Denmark during 2007-2011 and found 19 pregnancies in 12 women during which the mother ...
Levis Denise M DM Centers for Disease Control and Prevention, Division of Birth Defects and Developmental Disabilities, Atlanta, GA, USA. - - 2014
To explore women's knowledge, attitudes, and beliefs about adverse outcomes associated with smoking during pregnancy and which outcomes might motivate cessation; to explore reactions to graphic warnings depicting 2 adverse outcomes. Twelve focus groups were conducted with women of childbearing age who were current smokers. Participants had low to moderate ...
Mervic Liljana L Chamber of Dermatovenereology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia. Corresponding author: - - 2014
Psoriasis is not uncommon in the reproductive years and therefore in pregnant patients. There are limited data about the impact of psoriasis on the course and prognosis of pregnancy and about the impact of pregnancy on the course of psoriasis. Usually the disease improves during pregnancy and patients experience worsening ...
Leanza V V Department of Surgery Obstetrics and Gynecology, University of Catania, Catania, Italy - - - 2014
Among couples unable to conceive without any identifiable cause, 30% are defined as having unexplained infertility. Management depends on duration of infertility and age of female partner. In order to increase pregnancy rate, couples with infertility of unknown origin can undergo ovulation induction and intrauterine insemination. These techniques are able ...
Dias T T Faculty of Medicine, University of Kelaniya,Sri Lanka. - - 2014
Aims of this study were to compare the perinatal mortality rate and the prospective risk of stillbirth for each given gestational age and to ascertain whether it is safe to continue the pregnancy beyond 40 weeks of gestational age and induce labour at 41 weeks in low risk singleton pregnancies. ...
Mone F - - 2014
The aim of this retrospective observational study was to evaluate if performing fetal growth scans once or twice in the third trimester impacts on stillbirth rates in low risk pregnancies. The study was performed in a tertiary centre with 6,000 deliveries per annum. Data on all deliveries was collected via ...
Gencer Meryem M Çanakkale Onsekiz Mart Üniversitesi Tıp Fakültesi, Kadın Hastalıkları ve Doğum Bölümü, Çanakkale, Türkiye. - - 2014
In this study, we aimed to investigate Toxoplasma gondii seroprevalence and risk factors in pregnant women. A total of 196 patients, admitted to the clinic in the first trimester and with ongoing pregnancy follow-up of between May 2012 and January 2013, were included in the study. Toxoplasma IgG and IgM ...
Bolton Hl H Hinchingbrooke Hospital, Huntingdon, - - 2014
Rising caesarean section rates are frequently attributed to the medicalization of childbirth. Induction of labour (IOL) is a common obstetric intervention. NICE recommend IOL should be offered for post-dates pregnancy between 41(+0) and 42(+0) weeks gestation.(1) OBJECTIVES: To compare caesarean rates following IOL for post-dates pregnancy, with those delivering spontaneously ...
Hensch S S University of Leeds, Leeds, - - 2014
Primary immune thrombocytopenia (ITP) is a rare autoimmune condition that affects women of child bearing age and accounts for around 3% of thrombocytopenias at delivery.(1) It can lead to significant maternal and neonatal bleeding complications during labour and postpartum. The aim of this audit was to evaluate the management of ...
Kaler M M Barts Health, Whipps Cross University Hospital, London, - - 2014
: Multiple Endocrine Neoplasia Type 1 (MEN 1) is a rare inherited disorder caused by mutations in the tumour suppressor gene MEN 1. It is characterised by a predisposition towards the development of parathyroid, anterior pituitary and entero-pancreatic tumours. Clinically, MEN 1 is defined following development of two out of ...
Cussen L L Department of Obstetrics and Gynaecology, Cork University Maternity Hospital, Cork, - - 2014
Severe acute maternal morbidity (SAMM) describes life threatening obstetric complications, and is used as an adjunct to maternal death confidential enquiries. Admission to the Intensive Care Unit (ICU) is commonly used as a marker for SAMM. CUMH is the only maternity hospital of its size in Ireland co-located with a ...
White E E City Hospital, Birmingham, - - 2014
: Thromboembolism is associated with significant maternal morbidity and is a leading cause of death in pregnancy. We present a 26 year old, para 2 woman who attended the combined haematology/obstetric clinic. She was diagnosed with an extensive femoral DVT at 38 weeks gestation and was given therapeutic low molecular ...
Wood Sd S Nottingham University Hospitals, Nottingham, - - 2014
: Hypertensive disorders are one of the commonest disorders encountered during pregnancy and carry an increased risk for both mother and baby. A retrospective audit was carried out on the antenatal care of 30 women presenting to Nottingham City Hospital with pre-eclampsia or gestational hypertension from August 2013. Care was ...
Roberts Al A Nottingham University Hospitals NHS Trust/ University of Nottingham, Nottingham, - - 2014
: Abnormal proteinuria (a urinary protein creatinine ratio (PCR) >30 mg/mmol), combined with new onset hypertension in pregnancy, is the hallmark of pre-eclampsia. NICE guidelines(1) recommend that a urine dipstick test is performed at the 6-8 week postnatal check to ensure resolution but there is evidence to suggest that follow ...
Hodson K K Royal Victoria Infirmary, NUTH NHS Foundation Trust, Newcastle Upon Tyne, - - 2014
Haemophagoctic Lymphohistiocytosis (HLH) is a rare systemic haematological condition characterised by fever, cytopenia, liver dysfunction, hepatosplenomegaly and hyperferritinaemia. The very poor prognosis associated with HLH may be improved by early diagnosis and chemotherapy. There have been very few case reports of HLH in pregnancy. A 41-year-old woman was admitted at ...
Walter Sl S University Hospitals Bristol NHS Trust, Bristol, - - 2014
Chlamydia Psittaci infection is rare in pregnancy but can be associated with severe feto-maternal morbidity and mortality. Failure to identify at risk patients may delay diagnosis and appropriate treatment. A 30 year old nulliparous woman presented at 31 weeks gestation with pyrexia, vomiting and malaise. She had no significant past ...
Ridout Ae A Guys and St Thomas' NHS Foundation Trust, London, - - 2014
Sickle cell disease (SCD) and multiple pregnancies have both independently been associated with adverse pregnancy outcomes. Through our case series we observe the impact of multiple pregnancy on SCD morbidity, on which there is currently limited data. With multidisciplinary and protocol driven care, we identify a pathway, which could positively ...
Ng Kyb K Department of Obstetrics and Gynaecology, Ealing Hospital, London, - - 2014
: The prevalence of maternal obesity has increased to 16-19% in the early 2000s; it is one of the most common risk factors for maternal and fetal morbidity and mortality. About 50% of women who died were obese as reported by the last two 'Saving Mothers' Lives Reports' in 2007(1) ...
Robb Ao A The Simpson Centre for Reproductive Health, The Royal Infirmary of Edinburgh, Edinburgh, - - 2014
Current risk assessment guidelines for pre-eclampsia are unable to reliably predict adverse outcomes and thus inform management. This study investigated the association and predictive value of urinary albumin: creatinine ratio (ACR) in pregnancy for adverse outcomes. Demographic, clinical and biochemical data were collected, retrospectively, for 914 pregnant women who had ...
Lacey L L University Hospitals Coventry and Warwickshire, Coventry, - - 2014
Cardiac disease is now the leading cause of maternal death in the United Kingdom and the RCOG advises that all women with a history of cardiac disease should have a risk assessment in a joint multidisciplinary clinic with a clear plan for delivery being drawn up.(1) AIM: Does multidisciplinary team ...
Fathulla B B Royal Free Hospital, London, - - 2014
Interventions, including commencement of antiretroviral therapy (ARV), have decreased the rate of MTCT to less than 1%. This study looks at women who commenced ARV therapy during pregnancy as this group may be at high risk of MTCT. A retrospective cohort study of HIV-positive women commencing ARV during pregnancy at ...
Nelson Mc M University of Nottingham, Nottingham, - - 2014
Epilepsy is a common neurological disease in pregnancy. There is an increased risk of teratogenesis in pregnant women taking antiepileptic drugs (AEDs). Stopping medication can result in seizures, potentially increasing maternal and fetal morbidity. Clearance of newer drugs (lamotrigine and levetiracetam) increases in pregnancy but routinely measuring drug serum concentrations ...
Pickering M M Surrey and Sussex Healthcare NHS Trust, Redhill, - - 2014
Posterior reversible encephalopathy syndrome (PRES) is a neurotoxic state associated with unique magnetic resonance imaging (MRI). In pregnancy PRES is associated with pre eclampsia and eclampsia. Pre eclampsia and eclampsia induced PRES is managed by treating the cause. It is essential to treat PRES promptly in order to prevent permanent ...
Selvarajah Sl S Barts and the London, School of Medicine and Dentistry, London, - - 2014
Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting seen in women during pregnancy and often results in hospital admission. A 33 year old Caucasian woman in her first pregnancy, presented at 13 weeks gestation with a 6 weeks history of significant vomiting and weight loss of 6 ...
Wong Sh Sh North Manchester General Hospital, Manchester, - - 2014
: Folate deficiency causes macrocytic anaemia and pancytopenia. In severe cases it may also be associated with neurological signs and symptoms such as memory loss and irritability. Poor nutrition, alcoholism or increased requirement state, such as in pregnancy and lactation are some of the causes for folate deficiency. Although folate ...
O'Kane M M Maidstone and Tunbridge Wells NHS Trust, Tunbridge Wells, - - 2014
: Echinococcosis, often referred to as hydatid disease, is caused by an infection with the tapeworm Echinococcus. Cystic hydatidosis is known to be a significant public health problem in certain regions, however the worldwide prevalence is underestimated and in the UK, hyadtidosis is uncommon. We present an unusual case of ...
Munyame Cr C Royal Bournemouth and Christchurch Hospitals, Bournemouth, - - 2014
Peptic ulcer disease is relatively uncommon in pregnancy and the perperium. Vomiting on the other hand is a common symptom. We present a case of an acute abdomen which was secondary to a perforated Gastric ulcer in Pregnancy. A 40 year old para 2 (2 previous caesarean sections) booked under ...
Bentham Gl G St Michael's Hospital, Bristol, - - 2014
We aim to establish which measure of obesity is most useful in predicting mode of delivery. Obesity is a major risk factor for adverse events in pregnancy. 'Body mass index' (BMI) has been the widely accepted measure of obesity. However, 'waist to hip ratio' (WHR) is thought to better reflect ...
Mone F F National Maternity Hospital, Dublin, Ireland Royal Maternity Hospital, Belfast, - - 2014
To determine if performing fetal growth scans once or twice in the third trimester of pregnancy has an impact on the stillbirth rate in low-risk pregnancies A retrospective observational study was performed in a tertiary centre. Data was collected using the computerised Northern Ireland Maternity System (NIMATs) on all births ...
Makhadiyeva D D Central Manchester University Hospitals, St Mary's Hospital, Manchester, - - 2014
To audit a specialist antenatal clinic at St Mary's hospital in managing obstetric patients with renal disease and evaluate pregnancy outcomes in those patients against set standards. Data from patients with pre-existing renal disease managed in the clinic from January 2007 to December 2011 was included in the study. CKD ...
Usman S S Imperial College Healthcare NHS Trust, London, - - 2014
In the UK, 2.2 per 1000 women giving birth have HIV.(1) Routine antenatal screening and BHIVA guidelines(1) recommending multidisciplinary input have reduced mother-to-child HIV transmission (MTCT). Antiretroviral therapy (ART) is recommended to prevent MTCT and for maternal welfare. In those with a low viral load, vaginal delivery is safe.(1) However, ...
McPherson Kc K NHS Greater Glasgow and Clyde, Glasgow, - - 2014
Preterm delivery is the leading cause for infant mortality and morbidity. Cervical incompetence is a recognised cause for both extreme prematurity and second trimester loss. Use of cervical sutures may reduce these risks. We present an assessment of cervical suture use in a busy regional centre. Women who had an ...
Carter J J Guy's and St Thomas' NHS Foundation Trust, London, - - 2014
: Preterm birth (PTB) or mid-trimester loss is rare following term pregnancy. Caesarean section carried out at full dilatation (FDCS) is associated with increased clinical challenges(1). The integrity of the cervix may be affected by the uterine incision performed late in labour(2), however, there are few reports of clinical outcome ...
Morris A A Anu Research Centre, Department of Obstetrics and Gynaecology, University College Cork, Cork, Ireland Cork University Maternity Hospital, Cork, - - 2014
: In the UK and Ireland, second-trimester miscarriage is defined as pregnancy loss after the 14th and before the 24th week of gestation.(1) Those who suffer a second-trimester loss represent a small cohort but experience significant morbidity associated with both their index loss and subsequent pregnancies.(1) The literature on this ...
Bonney Ea E The Leeds Teaching Hospitals NHS Trust, Leeds, UK University of Leeds, Leeds, - - 2014
Around 11,000 infants are born < 33 weeks gestation annually in the UK. Cervical weakness is associated with midtrimester birth, and placement of a reinforcing suture is a strategy used to preserve or restore both cervical strength and length. McDonald's approach encircles the vaginal portion of the cervix, the Shirodkar ...
Madipola N N Barking, Havering, Redbridge University Teaching Hospital, Romford, - - 2014
: Severe intra-uterine growth restriction (IUGR) is significantly associated with intra-uterine and perinatal morbidity and mortality. There are no reliable screening tools and currently, monitoring is with Doppler ultrasound after the diagnosis has been made. The vessels interrogated to decide optimal timing of delivery include the umbilical artery and middle ...
Kapoor D D Department of Maternal Medicine, Nottingham University Hospitals NHS Trust, Nottingham, - - 2014
We observed that some women with glomerular collagen disorders (Alport's syndrome (AS) or thin basement membrane (TBM) disease) had particularly pronounced increase in proteinuria during pregnancy. Disease-specific pregnancy outcomes for women with AS/TBM are not well reported. The aim of the analysis is to test the hypothesis that these conditions ...
Halabi Rs R Leeds Teaching Hospitals Trust, Leeds, - - 2014
: Bernard Soulier Syndrome is a rare disorder of platelets, inherited predominantly as an autosomal recessive trait presenting with severe thrombocytopaenia and prolonged bleeding time, with the presence of extremely large platelets; it is associated with a high risk of serious bleeding for the mother and the neonate. Its prevalence ...
Raykova T T St Helier Hospital, Carshalton, - - 2014
This is a case presentation aiming to draw attention to the clinical suspicious of pheochromocytoma as a differential of severe hypertension in labour. Pheochromocytoma in a pregnant woman is extremely rare (1:54,000 pregnancies)(1) but life threatening condition. The signs and symptoms are variable, with hypertension being one of the most ...
Palmer Ce C Wirral University Teaching Hospital NHS Foundation Trust, Liverpool, - - 2014
: Obstetricians need to be aware of known complications related to bariatric surgeries and the diagnostic difficulties in pregnancy. We report a rare case of G2P1 28 year old with previous laparoscopic Roux-en-Y gastric bypass surgery. She had an uncomplicated first pregnancy seven months post bariatric surgery following 44 kg ...
Stoumpos Ss S Renal and Transplant Unit, Western Infirmary Glasgow, Glasgow, - - 2014
Fertility rapidly returns to women after successful kidney transplantation. The aim of this study was to collect information about pregnancy, delivery and renal outcomes among all kidney transplant recipients in our centre. Pregnant women with a kidney transplant were identified through our prospectively maintained electronic patient record and case-notes between ...
Pickering M M Surrey and Sussex Healthcare NHS Trust, Redhill, - - 2014
Takayasu's arteritis is a chronic idiopathic arteritis affecting the aorta and its primary branches. The symptoms of the disease are varied and patients can present asymptomatically with impalpable pulses. The incidence of Takayasu's is higher in females than that of males, and the disease most commonly presents between ages 15 ...
Neville G G National Maternity Hospital, Holles Street, Dublin, - - 2014
: Recent guidelines suggest intensive monitoring and consideration for delivery at 37 weeks for all small for gestational age (SGA) foetuses.(1) Adopting such an approach has considerable resource implications. This study aimed to retrospectively analyse trends in stillbirth in a major obstetric unit to ascertain if adhering to suggested guidelines ...
Ismail L L Buckinghamshire Healthcare NHS Trust, Aylesbury, - - 2014
Spontaneous adrenal haemorrhage is a very rare condition. To date there have been only 13 reported cases associated with pregnancy. A 29 year old para 2+5 presented at 38 weeks gestation with severe right loin pain. She had an otherwise uneventful pregnancy, and no significant medical history. Her observations were ...
Sadrudin F F University Hospitals Coventry and Warwickshire, Coventry, - - 2014
Maternal serum pregnancy associated plasma protein A (PAPP-A) is derived from the placenta and is a component of combined screening. When combined with maternal age, fetal nuchal translucency and maternal serum free β-hCG it has a detection rate of 85-90% for trisomy 21 (1). PAPP-A levels are influenced by other ...
Obeney-Williams J J Camden and Islington Mental Helath Trust, London, - - 2014
Studies have shownsubstance abuse among pregnant women can cause intra uterine growth retardation([4]) (IUGR) Pregnant women disclosing substance misuse before or during pregnancy were intensively monitored and this pilot represents the last six months of data. Women were asked about alcohol and drug use at booking both before and during ...
Walker L L Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, - - 2014
: Arthrogryposis is a complex diagnosis which may result in significant disability due to mobility problems or neonatal mortality due to pulmonary hypoplasia. Long term outcomes are difficult to predict. Antenatal information was collected retrospectively from a variety of regional validated databases. Follow up data was obtained from post mortem ...
Scarr C C University Hospital of Wales, Cardiff, - - 2014
: Haemophilia A and B are bleeding disorders inherited in an X linked recessive manner. Female carriers of these conditions have a 50% chance of delivering an affected infant when pregnant with a male fetus. Current British Society of Haematology guidelines for the care of carrier women recommends third trimester ...
Naughton M M University of Sheffield, Sheffield, - - 2014
Obstetric cholestasis (OC) is an incompletely understood hepatobiliary disease that typically affects women in the third trimester of pregnancy. It is associated with increased morbidity and mortality for the fetus, including intrauterine fetal death (IUFD). However, the diagnosis is complex and requires exclusion of other pregnancy-related complications and the serological ...
Goh Ay A NHS Tayside, Dundee, - - 2014
To investigate maternal and perinatal outcomes for women with singleton pregnancies with polyhydramnios in Tayside. All women diagnosed with polyhydramnios (AFI ≥ 25 cm/deepest pool ≥ 8 cm) between 01/01/13-31/10/13 were included. All women had an ultrasound scan (USS) assessment of fetal anatomy and a random blood sugar assessment as ...
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