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Ghosh Kanjaksha K Department of Haemostasis and Thrombosis, National Institute of Immunohaematology (ICMR), KEM Hospital, 13th floor, Parel, Mumbai, 400 012, - - 2014
We read with interest the report by Rodger et al [1] on thrombophilia associated with placenta-mediated pregnancy complications. The statistical rigor with which this multicentric study was carried out deserves critical acclaim. For the first time, the authors have tried to dissect different placental components of pregnancy related complications and associate ...
Zhang Y Y Department of Obstetrics and Gynecology, The first Affiliated Hospital, Sun Yat-sen University , Guangzhou , - - 2014
We investigated the pregnancy outcome of overweight and obese Chinese women with gestational diabetes mellitus (GDM). Patients diagnosed as GDM from January 2010 to December 2011 were categorised into three groups, as normal weight, overweight and obese, according to the maternal pre-pregnancy body mass index (BMI) (kg/m(2)), 18.5-24.9, 25-29.9 and ...
Meuli Martin M Department of Pediatric Surgery, University Children's Hospital Zurich, Steinwiesstrasse 75, 8032, Zurich, Switzerland, - - 2014
Formerly, the disastrous cluster of neurologic deficits and associated neurogenic problems in patients with myelomeningocele (MMC) was generally thought to solely result from the primary malformation, i.e., failure of neurulation. Today, however, there is no doubt that a dimensional additional pathogenic mechanism exists. Most likely, it contributes much more to ...
Tonni Gabriele G Prenatal Diagnostic Service, Department of Obstetrics and Gynecology, Guastalla Civil Hospital, AUSL Reggio Emilia, Via Amendola 1, Reggio Emilia, Italy, - - 2014
We describe a previously unreported case of immature teratoma originating from the tela chorioidea of the third ventricle diagnosed during labor at term of pregnancy. Postnatal MR imaging and pediatric neurosurgery with postnatal outcome at 6 months of age are reported.
Adanikin Abiodun I - - 2014
High maternal and perinatal mortalities occur from deliveries conducted in prayer houses in Nigeria. Although some regulatory efforts have been deployed to tackle this problem, less attention has been placed on the possible motivation for seeking prayer house intervention which could be hinged on the spiritual belief of patients about ...
Escobar-Diaz Maria C MC Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts. Electronic address: - - 2014
Patients with heterotaxy syndrome (HS) have a range of anomalies and outcomes. There are limited data on perinatal outcomes after prenatal diagnosis. To determine the factors influencing perinatal and infant outcomes, we analyzed prenatal and postnatal variables in fetuses with HS from 1995 to 2011. Of 154 fetuses with HS, ...
Hassan Noura N Department of Obstetrics and Gynecology, Jewish General Hospital, McGill University, Montreal, Quebec, - - 2014
Objective Marfan syndrome (MFS) is a rare connective tissue disease with significant risk for adverse cardiovascular outcomes. Our objective was to evaluate pregnancy and cardiovascular outcomes in pregnant women with MFS. Study Design We conducted a population-based retrospective cohort study using the Healthcare Cost and Utilization Project Nationwide Inpatient Sample (HCUP NIS) ...
Alarfaj Abdurhman Saud AS Division of Rheumatology, Department of Medicine, College of Medicine, King Saud University, P.O. Box 34471, Riyadh, 11468, Saudi Arabia, - - 2014
Intravenous cyclophosphamide (IV CYC) has been and still used for treatment of severe manifestations of systemic lupus erythematosus (SLE), a disease occurring predominantly in women. IV CYC has been shown to predispose patients to ovarian failure and adverse pregnancy outcomes. We studied the impact of prior IV CYC treatment on ...
Korenis Panagiota P Bronx Lebanon Hospital Center, Affiliated with Albert Einstein College of Medicine, Bronx, NY, USA, - - 2014
In psychiatry, pregnancy introduces an element into the treatment setting that is complex and may require exploration. Often, in the psychotherapeutic relationship, the psychiatrist may use therapeutic techniques and provide no self disclosure to the patient by Tinsley (Am J Psychiatry 160(1): 27-31, 2003). The patient reveals all of their ...
Gaskins Audrey J AJ Departments of Nutrition, Epidemiology, Environmental Health, and Biostatistics, Harvard School of Public Health, the Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, and the Department of Obstetrics, Gynecology and Reproductive Biology, the Channing Division of Network Medicine, and the Connors Center for Women's Health and Gender Biology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, - - 2014
To evaluate prospectively the relationship between prepregnancy folate intake and risk of spontaneous abortion and stillbirth. Women in the Nurses' Health Study II who self-reported a pregnancy between 1992 and 2009 were included in this analysis. Dietary folate and supplement use was assessed every 4 years, starting in 1991, by ...
Williamson Catherine C Women's Health Academic Centre, King's College London, and Department of Obstetrics and Gynaecology, University College London, London, United - - 2014
Intrahepatic cholestasis of pregnancy is the most common pregnancy-specific liver disease that typically presents in the third trimester. The clinical features are maternal pruritus in the absence of a rash and deranged liver function tests, including raised serum bile acids. Intrahepatic cholestasis of pregnancy is associated with an increased risk ...
Onicescu Georgiana G Department of Public Health Sciences, Medical University of South Carolina, Carolina, SC, 29425, USA, - - 2014
In this paper, we propose a novel spatial importance parameter hierarchical logistic regression modeling approach that includes measurement error from misalignment. We apply this model to study the relationship between the estimated concentration of soil metals at the residence of mothers and the development of intellectual disability (ID) in their ...
Gorman Margaret C MC Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, OR. Electronic address: - - 2014
Methamphetamine use is widespread. Our goal was to examine the effects of methamphetamine use on various maternal and neonatal outcomes. We conducted a retrospective cohort study looking at all pregnancies between 2005 and 2008 in the state of California associated with a diagnosis of methamphetamine use. Outcomes examined included: gestational ...
Hamed Hossam O HO Department of Obstetrics and Gynecology, Qassim University, Burraidah, Saudi Arabia; Department of Obstetrics and Gynecology, Assiut University, Assiut city, Egypt. Electronic address: - - 2014
To compare outcomes between elective delivery at 37weeks of pregnancy and expectant management among pregnant women with mild to moderate chronic hypertension. In a two-center study, 76 women with mild to moderate chronic hypertension were randomly allocated to planned delivery at 37 completed weeks (group A) or expectant management for ...
Timor-Tritsch I E IE NYU School of Medicine, Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, New York, - - 2014
To provide futher sonographic, clinical and histologic evidence that cesarean scar pregnancy (CSP) is a precursor and an early form of second and third trimester morbidly adherent placenta (MAP). We identified 10 cases of CSP fulfilling published ultrasound criteria. Nine patients, had counseling and offered early termination, but decided to ...
Helmy S S Department of Gynaecology and Obstetrics, Medical University of Vienna, Vienna 1090, - - 2014
To determine the optimal serum β-hCG cut-off level to predict MTX treatment success in tubal ectopic pregnancy (EP). Data of 240 women, who presented between 2003 and 2011 at the Department of Gynecology and Obstetrics, Medical University of Vienna, with tubal EP and who received MTX as primary treatment, were ...
Sun Shuiya S Department of Endocrinology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Jiaxing Maternity and Child Health Care Hospital, Jiaxing, Zhejiang, - - 2014
We investigated thyroid function and the impact of gestational transient thyrotoxicosis (GTT) on pregnancy outcome in patients with hyperemesis gravidarum (HG; n = 143) who were hospitalized for rehydration. Serum thyroid-stimulating hormone (TSH), free T3 (FT3), free T4 (FT4), thyroid globulin antibody (TgAb), thyroid peroxidase antibody (TPOAb) and hCG were measured after ...
Iskender Cantekin C Department of Perinatology, Dr Zekai Tahir Burak Research and Training Hospital, Ankara, - - 2014
Behçet's disease (BD) is a rare, chronic, multisystemic disease of unknown cause. BD is characterized by mucocutaneous, ocular, vascular and central nervous system manifestations and is also associated with thrombogenicity. In this retrospective analysis we investigated the relation between gestation and BD. This retrospective study consisted of 49 pregnancies in ...
Ferrazzani Sergio S Department of Obstetrics and Gynaecology, Catholic University of Sacred - - 2014
Massive post-partum hemorrhage (PPH) is an important cause of maternal death that occurs as a complication of delivery. We report a large case series to evaluate the efficacy of uterine balloon tamponade to treat PPH avoiding hysterectomy. This prospective study was conducted in two Italian hospitals (from December 2002 to ...
Nakasuji Takashi T Division of Reproductive Medicine, National Center for Child Health and - - 2014
The aim of this study was to assess the efficacy of assisted hatching (AH) in assisted reproductive technology (ART) treatment. In this retrospective observational study, the data of patients who were registered in the National ART Registry System of Japan between January and December 2010 were analyzed. The descriptive statistics ...
Son Jung Bin JB Department of Obstetrics and Gynecology, Pusan National University School of Medicine, - - 2014
An appropriate endometrial condition and vascular supply are usually considered essential for implantation of an embryo. This study was performed to assess the role of endometrial and uterine vascularity status measurement in predicting pregnancy outcome during frozen-thawed embryo transfer cycles. A total of 70 infertile women were recruited with controlled ...
Chishima Fumihisa F Departments of Obstetrics and - - 2014
A 34-year-old, gravida 0 para 0 Japanese woman visited a regional hospital complaining of dysmenorrhea, hematuria during menstruation, and right inguinal pain. She had a history of dysmenorrhea and three prior rounds of in vitro fertilization with embryo transfer, which were all with transfers of cryopreserved-thawed single embryos in natural ...
Tran Duong Thuy DT Centre for Health Research, University of Western Sydney, New South - - 2014
Objective: Birth records and hospital admission records are valuable for research on maternal smoking, but individually are known to under-estimate smokers. This study investigated the extent to which combining data from these records enhances the identification of pregnant smokers, and whether this affects research findings such as estimates of maternal ...
Cao Shasha S Department of Radiology, Peking University People's Hospital, Beijing 100044, - - 2014
Cesarean scar pregnancy (CSP) is a very rare but life-threatening entity and there is no optimal management strategy. Here we report a successfully conservative treatment of CSP. We retrospectively analyzed the clinical data of 54 women with CSP, who underwent uterine artery embolization between January 2007 and September 2012 at ...
Liu Xiaoli X Department of Obstetrics, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, - - 2014
In the last few decades, there has been a delay in first-time pregnancies, and the average age of women at the time of delivery has increased in many countries. Advanced maternal age is associated with adverse pregnancy outcomes. This study aimed to determine the present trends and pregnancy outcomes related ...
Nielsen Stine Yde - - 2014
A high risk for obstetric complications has been reported among women infected with Coxiella burnetii, the causative agent of Q fever, but recent studies have failed to confirm these findings. We reviewed national data collected in Denmark during 2007-2011 and found 19 pregnancies in 12 women during which the mother ...
Levis Denise M DM Centers for Disease Control and Prevention, Division of Birth Defects and Developmental Disabilities, Atlanta, GA, USA. - - 2014
To explore women's knowledge, attitudes, and beliefs about adverse outcomes associated with smoking during pregnancy and which outcomes might motivate cessation; to explore reactions to graphic warnings depicting 2 adverse outcomes. Twelve focus groups were conducted with women of childbearing age who were current smokers. Participants had low to moderate ...
Mervic Liljana L Chamber of Dermatovenereology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia. Corresponding author: - - 2014
Psoriasis is not uncommon in the reproductive years and therefore in pregnant patients. There are limited data about the impact of psoriasis on the course and prognosis of pregnancy and about the impact of pregnancy on the course of psoriasis. Usually the disease improves during pregnancy and patients experience worsening ...
Leanza V V Department of Surgery Obstetrics and Gynecology, University of Catania, Catania, Italy - - - 2014
Among couples unable to conceive without any identifiable cause, 30% are defined as having unexplained infertility. Management depends on duration of infertility and age of female partner. In order to increase pregnancy rate, couples with infertility of unknown origin can undergo ovulation induction and intrauterine insemination. These techniques are able ...
Dias T T Faculty of Medicine, University of Kelaniya,Sri Lanka. - - 2014
Aims of this study were to compare the perinatal mortality rate and the prospective risk of stillbirth for each given gestational age and to ascertain whether it is safe to continue the pregnancy beyond 40 weeks of gestational age and induce labour at 41 weeks in low risk singleton pregnancies. ...
Mone F - - 2014
The aim of this retrospective observational study was to evaluate if performing fetal growth scans once or twice in the third trimester impacts on stillbirth rates in low risk pregnancies. The study was performed in a tertiary centre with 6,000 deliveries per annum. Data on all deliveries was collected via ...
Gencer Meryem M Çanakkale Onsekiz Mart Üniversitesi Tıp Fakültesi, Kadın Hastalıkları ve Doğum Bölümü, Çanakkale, Türkiye. - - 2014
In this study, we aimed to investigate Toxoplasma gondii seroprevalence and risk factors in pregnant women. A total of 196 patients, admitted to the clinic in the first trimester and with ongoing pregnancy follow-up of between May 2012 and January 2013, were included in the study. Toxoplasma IgG and IgM ...
Bolton Hl H Hinchingbrooke Hospital, Huntingdon, - - 2014
Rising caesarean section rates are frequently attributed to the medicalization of childbirth. Induction of labour (IOL) is a common obstetric intervention. NICE recommend IOL should be offered for post-dates pregnancy between 41(+0) and 42(+0) weeks gestation.(1) OBJECTIVES: To compare caesarean rates following IOL for post-dates pregnancy, with those delivering spontaneously ...
Hensch S S University of Leeds, Leeds, - - 2014
Primary immune thrombocytopenia (ITP) is a rare autoimmune condition that affects women of child bearing age and accounts for around 3% of thrombocytopenias at delivery.(1) It can lead to significant maternal and neonatal bleeding complications during labour and postpartum. The aim of this audit was to evaluate the management of ...
Kaler M M Barts Health, Whipps Cross University Hospital, London, - - 2014
: Multiple Endocrine Neoplasia Type 1 (MEN 1) is a rare inherited disorder caused by mutations in the tumour suppressor gene MEN 1. It is characterised by a predisposition towards the development of parathyroid, anterior pituitary and entero-pancreatic tumours. Clinically, MEN 1 is defined following development of two out of ...
Cussen L L Department of Obstetrics and Gynaecology, Cork University Maternity Hospital, Cork, - - 2014
Severe acute maternal morbidity (SAMM) describes life threatening obstetric complications, and is used as an adjunct to maternal death confidential enquiries. Admission to the Intensive Care Unit (ICU) is commonly used as a marker for SAMM. CUMH is the only maternity hospital of its size in Ireland co-located with a ...
White E E City Hospital, Birmingham, - - 2014
: Thromboembolism is associated with significant maternal morbidity and is a leading cause of death in pregnancy. We present a 26 year old, para 2 woman who attended the combined haematology/obstetric clinic. She was diagnosed with an extensive femoral DVT at 38 weeks gestation and was given therapeutic low molecular ...
Wood Sd S Nottingham University Hospitals, Nottingham, - - 2014
: Hypertensive disorders are one of the commonest disorders encountered during pregnancy and carry an increased risk for both mother and baby. A retrospective audit was carried out on the antenatal care of 30 women presenting to Nottingham City Hospital with pre-eclampsia or gestational hypertension from August 2013. Care was ...
Roberts Al A Nottingham University Hospitals NHS Trust/ University of Nottingham, Nottingham, - - 2014
: Abnormal proteinuria (a urinary protein creatinine ratio (PCR) >30 mg/mmol), combined with new onset hypertension in pregnancy, is the hallmark of pre-eclampsia. NICE guidelines(1) recommend that a urine dipstick test is performed at the 6-8 week postnatal check to ensure resolution but there is evidence to suggest that follow ...
Hodson K K Royal Victoria Infirmary, NUTH NHS Foundation Trust, Newcastle Upon Tyne, - - 2014
Haemophagoctic Lymphohistiocytosis (HLH) is a rare systemic haematological condition characterised by fever, cytopenia, liver dysfunction, hepatosplenomegaly and hyperferritinaemia. The very poor prognosis associated with HLH may be improved by early diagnosis and chemotherapy. There have been very few case reports of HLH in pregnancy. A 41-year-old woman was admitted at ...
Walter Sl S University Hospitals Bristol NHS Trust, Bristol, - - 2014
Chlamydia Psittaci infection is rare in pregnancy but can be associated with severe feto-maternal morbidity and mortality. Failure to identify at risk patients may delay diagnosis and appropriate treatment. A 30 year old nulliparous woman presented at 31 weeks gestation with pyrexia, vomiting and malaise. She had no significant past ...
Ridout Ae A Guys and St Thomas' NHS Foundation Trust, London, - - 2014
Sickle cell disease (SCD) and multiple pregnancies have both independently been associated with adverse pregnancy outcomes. Through our case series we observe the impact of multiple pregnancy on SCD morbidity, on which there is currently limited data. With multidisciplinary and protocol driven care, we identify a pathway, which could positively ...
Ng Kyb K Department of Obstetrics and Gynaecology, Ealing Hospital, London, - - 2014
: The prevalence of maternal obesity has increased to 16-19% in the early 2000s; it is one of the most common risk factors for maternal and fetal morbidity and mortality. About 50% of women who died were obese as reported by the last two 'Saving Mothers' Lives Reports' in 2007(1) ...
Robb Ao A The Simpson Centre for Reproductive Health, The Royal Infirmary of Edinburgh, Edinburgh, - - 2014
Current risk assessment guidelines for pre-eclampsia are unable to reliably predict adverse outcomes and thus inform management. This study investigated the association and predictive value of urinary albumin: creatinine ratio (ACR) in pregnancy for adverse outcomes. Demographic, clinical and biochemical data were collected, retrospectively, for 914 pregnant women who had ...
Lacey L L University Hospitals Coventry and Warwickshire, Coventry, - - 2014
Cardiac disease is now the leading cause of maternal death in the United Kingdom and the RCOG advises that all women with a history of cardiac disease should have a risk assessment in a joint multidisciplinary clinic with a clear plan for delivery being drawn up.(1) AIM: Does multidisciplinary team ...
Fathulla B B Royal Free Hospital, London, - - 2014
Interventions, including commencement of antiretroviral therapy (ARV), have decreased the rate of MTCT to less than 1%. This study looks at women who commenced ARV therapy during pregnancy as this group may be at high risk of MTCT. A retrospective cohort study of HIV-positive women commencing ARV during pregnancy at ...
Nelson Mc M University of Nottingham, Nottingham, - - 2014
Epilepsy is a common neurological disease in pregnancy. There is an increased risk of teratogenesis in pregnant women taking antiepileptic drugs (AEDs). Stopping medication can result in seizures, potentially increasing maternal and fetal morbidity. Clearance of newer drugs (lamotrigine and levetiracetam) increases in pregnancy but routinely measuring drug serum concentrations ...
Pickering M M Surrey and Sussex Healthcare NHS Trust, Redhill, - - 2014
Posterior reversible encephalopathy syndrome (PRES) is a neurotoxic state associated with unique magnetic resonance imaging (MRI). In pregnancy PRES is associated with pre eclampsia and eclampsia. Pre eclampsia and eclampsia induced PRES is managed by treating the cause. It is essential to treat PRES promptly in order to prevent permanent ...
Selvarajah Sl S Barts and the London, School of Medicine and Dentistry, London, - - 2014
Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting seen in women during pregnancy and often results in hospital admission. A 33 year old Caucasian woman in her first pregnancy, presented at 13 weeks gestation with a 6 weeks history of significant vomiting and weight loss of 6 ...
Wong Sh Sh North Manchester General Hospital, Manchester, - - 2014
: Folate deficiency causes macrocytic anaemia and pancytopenia. In severe cases it may also be associated with neurological signs and symptoms such as memory loss and irritability. Poor nutrition, alcoholism or increased requirement state, such as in pregnancy and lactation are some of the causes for folate deficiency. Although folate ...
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