OBJECTIVE: Assessment of anxiety levels in women and men before and after preconception counseling and during the first trimester of pregnancy. METHODS: Couples were recruited from the fertility clinic of the University Medical Center Nijmegen, the Netherlands. Anxiety was assessed using the 40-item Spielberger State-Trait Anxiety Inventory (STAI). RESULTS: 53 ...

Recent research suggests that stress, anxiety, and depression during pregnancy may have an impact on how the child develops. In this article, the central literature supporting this hypothesis is reviewed. Next, studies from our laboratory showing that differences in fetal heart rate patterns are associated with women's anxiety and depressive ...

The mother's brain is prepared by the hormones of pregnancy to show the strong maternal feelings that ensure the newborn is cared for. These hormones induce a cascade of changes in the brain, reducing stress reactions, evoking maternal behaviour and preparing the neuroendocrine circuits that drive the birth process and ...

BACKGROUND: The 'yips' is a psychoneuromuscular impediment affecting execution of the putting stroke in golf. Yips symptoms of jerks, tremors and freezing often occur during tournament golf and may cause performance problems. Yips-affected golfers add approximately 4.7 strokes to their scores for 18 holes of golf, and have more forearm ...

Fatigue is a common complaint among women throughout pregnancy and during the postpartum period. It is suggested that there are physical, psychological, and situational factors predisposing a woman to fatigue during pregnancy. Several studies have attempted to correlate levels of fatigue with other variables. While many of these studies have ...

BACKGROUND: Recent psychiatric literature, while indicating a high incidence of postpartum depression, contains a few clinical reports which support our observations that women with episodic bipolar disorder often remain well without treatment during pregnancy. Our retrospective study statistically examines the clinical course of 28 women with RDC typical bipolar disorder, ...

The Saccharomyces cerevisiae inositol polyphosphate 5-phosphatases (Inp51p, Inp52p, and Inp53p) each contain an N-terminal Sac1 domain, followed by a 5-phosphatase domain and a C-terminal proline-rich domain. Disruption of any two of these 5-phosphatases results in abnormal vacuolar and plasma membrane morphology. We have cloned and characterized the Sac1-containing 5-phosphatases Inp52p ...

BACKGROUND: Although pregnancy has frequently been described as a time of emotional well-being, some women experience significant antenatal depression that may require treatment with antidepressants. The purpose of this investigation was to examine the relative effects of early and late trimester exposure to fluoxetine and perinatal outcome. METHODS: Obstetric and ...

The objectives were to identify the stage/s of IVF treatment where a woman is most vulnerable to psychological stress, and to assess the Mean Affect Adjective Check List (MAACL) as a measure of psychological functioning during IVF treatment, which has hitherto not been reported. Thirty-seven women undergoing IVF treatment according ...

OBJECTIVE: The aims of this study were to establish prospectively the prevalence of objective bladder dysfunction before and after delivery by means of urodynamic investigations and to assess the effect of obstetric variables on bladder function. DESIGN: Prospective longitudinal study. Twin channel subtracted cystometry was performed in the standing and ...

Depression during pregnancy and after delivery is a problem for the mother and poses a threat to the health of the fetus, the infant, and the family members. Low birth-weight babies have an increased risk for impaired cognitive function, cardiac disease, vascular disease, and diabetes. The incidence of depression during ...

Metal working fluids (MWFs) are widely used in industry for metal cutting, drilling, shaping, lubricating, and milling. Potential for dermal exposure to MWFs exists for a large number of men and women via aerosols and splashing during the machining operations. It has been reported earlier that occupational exposure to MWFs ...

In vulnerable individuals, postpartum depression may be triggered by the disruption of neuropsychological processes during pregnancy and parturition. It is proposed that in Western societies pre- and postnatal psychological and instrumental needs are poorly met and this crisis may interact with neurophysiological factors in compromising maternal psychological functioning. The influence ...

Recent advances are beginning to shed light on the mechanisms whereby adverse psychosocial factors can influence pregnancy outcome. High levels of maternal stress have been linked to endocrine disturbances, which in turn increases the risk of preterm labor considerably. These observations have been supported by experimental animal models. Birth weight ...

BACKGROUND: The aim of the present study was to delineate the influence of maternal stress, social support and coping styles on depressed mood during pregnancy and the early postpartum period. METHODS: Beginning in the third month of pregnancy, data on numerous variables including daily stress (Hassles), state-anxiety (STAI-state), pregnancy-specific stress ...

Genuine stress incontinence is usually managed conservatively in women desirous of further childbearing. Tension-free vaginal taping is a relatively new method of surgical treatment of genuine stress incontinence. We report a case of pregnancy following the procedure. The patient was delivered by elective cesarean section. She remained continent throughout pregnancy ...

The internet and computers have already become an important part of the daily lives of many. Through the touch of a button we can now obtain almost any information we desire without even leaving our homes. Although pregnancy is a common physiological event, anxiety is one of its frequent accompaniments ...

OBJECTIVE: To determine whether women who get pregnant as a result of IVF differ psychologically from pregnant women who conceived naturally. DESIGN: Prospective, longitudinal study. SETTING: Healthy volunteers from outpatient infertility and obstetrics practices. PATIENT(s): Seventy-four women who became pregnant via IVF and 40 women conceiving without medical intervention. INTERVENTION(s): ...

The objective of the study was to examine moods and adjustment through the transition to parenthood as an issue affecting the couple; to examine not only the postpartum but also the pregnancy experience and to explore how each partner's experiences interact with those of the other. A longitudinal repeated measures ...

Stress during pregnancy affects the morphogenesis of embryonal brain, its structural and functional characteristics, and behavior of the progeny. Genetic mechanisms of this process remain unclear. Cytogenetic characteristics of neuroblasts were analyzed in 17-18-day embryos of rats selected by threshold excitability of the nervous system in health and after emotional ...

Abdominal aortic aneurysm (AAA) rupture is believed to occur when the mechanical stress acting on the wall exceeds the strength of the wall tissue. Therefore, knowledge of the stress distribution in an intact AAA wall could be useful in assessing its risk of rupture. We developed a methodology to noninvasively ...

OBJECTIVE: This report describes associations between body mass index (BMI; kg/m2), eating attitudes, and affective symptoms across pregnancy and the postpartum period in a sample of 64 women. METHODS: As part of a larger study, women were recruited during pregnancy and followed prospectively to 14 months postpartum. Measures included self-reported ...

QUESTIONOne of my patients suffers from anxiety and was using lorazepam to treat it. When she became pregnant, she stopped the medication immediately, but now she is worried about the potential effect on the baby because she was using the drug just after conception. Is this class of drugs safe ...

The authors focus on infant mental health interventions during pregnancy in response to stressors, behaviors, and difficulties experienced by the mother-to-be (as well as by the father-to-be and surrounding family or support system) that are likely to have a negative impact on the growth, development, behavior, and psychological environment of ...

The dynamics of physiological stress and thermal balance were investigated in men subjected to endogenous and exogenous heat loads. The study was conducted using the thermometric method. Substantial differences in the dynamics of the tested parameters and their quantitative characteristics were observed in 1 out of 8 participants. In this ...

Perceived stress and depressive symptoms were examined as correlates and predictors of smoking cessation during pregnancy in a sample of 819 pregnant smokers (454 baseline smokers and 365 baseline quitters). Women who quit early in pregnancy had lower levels of stress and depressive symptoms than baseline smokers. Adjusting for level ...

The use of antidepressants during pregnancy has undergone considerable scrutiny with respect to safety issues, though limited data with respect to dose management and symptom resolution is available. Previous reports on tricyclic antidepressants (TCAs) have demonstrated the need to adjust maternal dose later in pregnancy to maintain therapeutic serum concentrations. ...

This article examines surrogacy arrangements in Israel. The Law of Surrogacy was legislated in March 1996. Surrogacy agreements are strictly limited by the criteria set forth in the law. An authorizations committee was set up by the Ministry of Health to examine each application for approval of a surrogacy agreement. ...

This study examined the effect of an acute maternal stress response and anxiety on fetal heart rate. Seventeen healthy, 3rd-trimester pregnant women (mean age = 26 +/- 6 years) were instrumented for continuous electrocardiography, blood pressure (BP), respiration, and fetal heart rate (HR). Subjects completed the state anxiety subscale of ...

BACKGROUND: Some women dread and avoid childbirth despite desperately wanting a baby. This is called tokophobia. AIMS: To classify tokophobia for the first time in the medical literature. METHOD: Twenty-six women noted to have an unreasoning dread of childbirth were interviewed by the same psychiatrist, who was not the treating ...

OBJECTIVE: Maternal antenatal emotional attachment (MAEA) to the fetus has been proposed as an important factor for the emergence of harm to the unborn child. The present study investigated whether MAEA was associated with self-reported intent to harm the fetus. METHOD: Forty pregnant women, referred for psychological evaluation, completed a ...

BACKGROUND: Physical and sexual abuse has been associated with adverse pregnancy outcome in some studies. One cause may be physical trauma; others may be indirect, such as stress, anxiety, smoking or drug use in pregnancy. The aim of the present study was to assess the relationships among anxiety, history of ...

Several environmental factors affect the fetus and thereby the outcome of pregnancy. Recent studies have confirmed a relation between stress and pregnancy outcome; furthermore they have indicated that biological measures of stress may predict risk of complications. Altered sex ratio may be an interesting way of measuring the effect of ...

This study works towards a theoretical model of the relational self derived from the intensive examination of a small number of case studies of women going through their first pregnancy. The study is idiographic, grounded in the women's own accounts of the experience, and it is primarily qualitative. It employs ...

This prospective study tracked hassles, pregnancy-specific stress, and state anxiety during pregnancy. A second objective was to identify predictors of each stress dimension. Pregnant women (n=161) completed the Hassles Scale, the Pregnancy-Specific Stress Questionnaire (PEQ), and the state-anxiety scale (STAI-state) monthly, beginning in the third month of pregnancy. Hassles were ...

The neuroactive steroid allopregnanolone (3a-hydroxy-5a-pregnan-20-one, 3alpha,5alpha-THP) has been shown to be involved in the central nervous system's response to stress. This experiment investigated whether response to the neuroactive steroid allopregnanolone, a positive modulator of the GABA(A) receptor, would be altered in neonatal or adult rats previously exposed to a chronic ...

Symptoms of normal pregnancy have received scant attention in the literature and what is reported is largely unsubstantiated. Yet this is an important aspect of antenatal counselling and care which deserves further investigation if symptoms are to be interpreted correctly. Accordingly, we conducted a prospective controlled study of symptoms during ...

The literature on lipid peroxide levels in uncomplicated pregnancy is limited, but some reasonable conclusions are possible. Despite the lack of precision in the predominant measure of lipid oxidation, there is agreement across a large number of studies that the level of lipid peroxides in blood is generally higher in ...

OBJECTIVE: To determine whether knowledge of the possible cause of miscarriage reduces women's long term psychological distress. DESIGN: Prospective longitudinal study. SETTING: Harris Birthright Research Centre for Fetal Medicine, King's College Hospital Medical School, London. METHODS: In 143 women where a routine ultrasound scan at 10-14 weeks of gestation showed ...

As compared with 580 randomly chosen pregnant women without malformed offspring. 161 women with malformed offspring at the index pregnancy had a more frequent history of previous multiple offspring deaths and somewhat increased maternal age but were not different on social class, marital or cohabitation status or parity. As compared ...

OBJECTIVES: This study examined the association between gestation length and heat exposure during the summer months of the Chicago heat wave of 1995. METHODS: Birth data from Illinois vital records containing 11,792 singleton vaginal births were analyzed to calculate mean gestational ages. RESULTS: No evidence was found to suggest an ...

To assess women's symptoms of depression and anxiety during pregnancy and the postpartum year in the pregnancy after stillbirth; to assess relevance of time since loss. Cohort study with four assessments: in third trimester and 6 weeks, 6 months, and 12 months after birth. Outpatient departments of three district general ...

This study investigated the association between psychosocial stress and outcome of in-vitro fertilization and gamete intra-Fallopian transfer treatment. Ninety women, enrolled for treatment at a private infertility clinic, completed two self-administered psychometric tests (Bi-polar Profile of Mood States, POMS; and State-Trait Anxiety Inventory, STAI) and a questionnaire to ascertain demographic ...

There is little known about the effect of pregnancy and the puerperium on the risk for, and course of anxiety disorders. Initial case reports concerning the relationship between panic disorder (PD) and pregnancy/puerperium suggested that pregnancy protected against PD, while the postpartum period seemed to increase the risk for onset ...

OBJECTIVE: To describe the experience of a pregnancy after perinatal loss. DESIGN: Descriptive, open-ended responses to a self-completed questionnaire. SETTING: Questionnaires were distributed at a prenatal visit and completed in the office or at home. PARTICIPANTS: Seventy-two women who were 17 to 28 weeks pregnant, with a history of one ...

OBJECTIVE: To examine the concurrent and longitudinal associations between corticotropin-releasing hormone (CRH) and cortisol concentrations and depression and antisocial behavior (conduct disorder symptoms) in pregnant adolescents. METHOD: Fifty-nine adolescents were evaluated in early pregnancy (9-21 weeks' gestation), late pregnancy (32-34 weeks' gestation), and the postpartum period (4-5 weeks postpartum). Symptoms ...

The association between coping and pregnancy-specific distress was examined in 167 pregnant women at high medical risk. A population-appropriate coping inventory and prenatal distress measure were administered in mid-pregnancy (mean of 24 weeks gestation). Subjects experienced moderately high levels of distress about preterm delivery, physical symptoms, labor and delivery, weight ...

Stress is thought to be one of the biopsychosocial factors that contribute to adverse pregnancy outcomes, such as preterm labor and low birthweight. Identification of these factors (as in total number), and measurement of their individually perceived importance (severity) could lead to opportunities for intervention, and improved pregnancy outcome. A ...

This study integrates quantitative and qualitative research methods to examine the psychologic repercussions of multifetal pregnancy reduction, a recently developed reproductive technology. Two theoretical vantage points, descriptive psychiatry and psychoanalytic theory, were used to understand the emotional impact of the medical intervention, which involves aborting some but not all of ...

BACKGROUND: Bulimia nervosa affects women at a peak age of reproductive functioning, but few studies have examined the impact of pregnancy on bulimia. AIM: To examine the impact of pregnancy on symptoms of bulimia nervosa and associated psychopathology. METHOD: Women actively suffering from bulimia nervosa during pregnancy (n = 94) ...